Web Desc
Adipose Tissue Biology
joint with Neuronal Control of Appetite, Metabolism and Weight
Organizer(s): Sheila Collins, Karsten Kristiansen and Silvia Corvera
Date: January 24 - 29, 2010
Location: Keystone Resort, Keystone, CO, USA
Supported by The Directors' Fund
Summary of Meeting:
The study of adipose tissue has evolved over the years from merely being a passing note in most physiology texts to now playing center stage in the etiology of most metabolic diseases. This shift was assisted by early studies exploring the molecular signals and gene expression changes that dictate the differentiated state of a cell, for which the adipocyte was a model. Such studies led to the discovery of PPARgamma as one of those key regulators of adipogenesis, and later the realization that it was the pharmacologic target of the glitazone class of anti-diabetic agents. Further seminal studies from The Jackson Laboratories on mouse genetics of obesity paved the way for the discovery of adipocyte-derived regulatory hormones (“adipokines”) such as leptin and its receptor. These in turn ushered in the current state of vigorous investigation dissecting the molecular pathways of satiety and other aspects of signaling cross-talk between adipose tissue and other organs. The updated view of adipose tissue as a bona fide endocrine organ has been further extended to include it as a potential reservoir of stem cells for tissue engineering and an integral player in inflammatory status and insulin resistance. This meeting will cover these and other topics of the adipose biology field, including the role of angiogenesis in adipose tissue expansion; the white fat-brown fat debate; the contribution of the circadian clock to the hormonal and neural signals that coordinate food intake and activity for metabolic balance; and the connections between central and peripheral signals involved in the unanticipated lipodystrophic disorders resulting from such therapeutic regimens as antipsychotics and anti-retrovirals. A series of hot-topic sessions and short talks from submitted abstracts are also planned.
Scholarship Deadline: September 23 2009
Discounted Abstract Deadline: September 23 2009
Abstract Deadline: October 23 2009
Discounted Registration Deadline: November 24 2009
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK084688-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 24 | 3:00PM - 7:30PM
Registration
Room: Longs Peak Foyer


Sunday, January 24 | 6:30PM - 7:30PM
Refreshments
Room: Longs Peak Foyer


Sunday, January 24 | 7:30PM - 8:30PM
Keynote Address (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 1
Jeffrey M. Friedman, Rockefeller University, USA
Leptin’s Loop: Dissecting the Physiologic Systems Regulating Food Intake and Metabolism

Monday, January 25 | 7:00AM - 8:00AM
Breakfast
Room: Torreys 1-3, Shavano, Red Cloud


Monday, January 25 | 8:00AM - 11:15AM
Circadian Control of Adiposity and Metabolism (Joint)
Room: Grays/Longs Peaks

Speaker 1 of 6
* Martin G. Myers, Jr., University of Michigan, USA

Monday, January 25 | 8:00AM - 11:15AM
Circadian Control of Adiposity and Metabolism (Joint)
Room: Grays/Longs Peaks

Speaker 2 of 6
Joseph T. Bass, Northwestern University, USA
Clock and Per: Gene Network Controls on Metabolism/Adiposity

Monday, January 25 | 8:00AM - 11:15AM
Circadian Control of Adiposity and Metabolism (Joint)
Room: Grays/Longs Peaks

Speaker 3 of 6
Julian Mercer, Rowett Research Institute, UK
Effect of Rhythms, Diet and Feeding Patterns on Hypothalamic Gene Expression

Monday, January 25 | 8:00AM - 11:15AM
Circadian Control of Adiposity and Metabolism (Joint)
Room: Grays/Longs Peaks

Speaker 4 of 6
Georgios Paschos, University of Pennsylvania, USA
Short Talk: Obesity in Mice with Adipose Tissue-Specific Deletion of Bmal1

Monday, January 25 | 8:00AM - 11:15AM
Circadian Control of Adiposity and Metabolism (Joint)
Room: Grays/Longs Peaks

Speaker 5 of 6
Etienne Challet, CNRS, France
Synchronization of Multiple Circadian Clocks by Feeding

Monday, January 25 | 8:00AM - 11:15AM
Circadian Control of Adiposity and Metabolism (Joint)
Room: Grays/Longs Peaks

Speaker 6 of 6
Clifford J. Rosen, Maine Medical Center, USA
Short Talk: Nocturnin, a Circadian Clock Gene, Stimulates Adipogenesis by Promoting Nuclear Transport of PPARgamma

Monday, January 25 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Monday, January 25 | 11:15AM - 11:30AM
NIDDK Discussion of Funding Issues
Room: Grays/Longs Peak

Speaker 1 of 1
Philip F. Smith, NIDDK, National Institutes of Health, USA

Monday, January 25 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Monday, January 25 | 11:15AM - 1:00PM
Poster Setup
Room: Torreys 1-3, Shavano, Red Cloud


Monday, January 25 | 1:00PM - 10:00PM
Poster Viewing
Room: Torreys 1-3, Shavano, Red Cloud


Monday, January 25 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, January 25 | 5:00PM - 7:15PM
Angiogenesis and Adipose Mass: Factors and Regulation
Room: Longs Peak

Speaker 1 of 6
* Anna Krook, Karolinska Institutet, Sweden

Monday, January 25 | 5:00PM - 7:15PM
Angiogenesis and Adipose Mass: Factors and Regulation
Room: Longs Peak

Speaker 2 of 6
Silvia Corvera, University of Massachusetts Medical School, USA
Adipose Tissue Angiogenesis and the Development of Insulin Resistant in Human

Monday, January 25 | 5:00PM - 7:15PM
Angiogenesis and Adipose Mass: Factors and Regulation
Room: Longs Peak

Speaker 3 of 6
H. Roger Lijnen, University of Leuven, Belgium
Roles of MMPs in Development of Adipose Tissue

Monday, January 25 | 5:00PM - 7:15PM
Angiogenesis and Adipose Mass: Factors and Regulation
Room: Longs Peak

Speaker 4 of 6
Zofia Zukowska, University of Minnesota, USA
Neurogenic Regulation of Angiogenesis and adipogenesis – Role of Neuropeptid Y

Monday, January 25 | 5:00PM - 7:15PM
Angiogenesis and Adipose Mass: Factors and Regulation
Room: Longs Peak

Speaker 5 of 6
Dong-Hoon Kim, University of Cincinnati, USA
Short Talk: Differential Adipose Tissue Remodeling Related to Angiogenesis and Inflammation in Young Obesity-Prone C57Bl/6 Mice and Obesity-Resistant FVB/N Mice

Monday, January 25 | 5:00PM - 7:15PM
Angiogenesis and Adipose Mass: Factors and Regulation
Room: Longs Peak

Speaker 6 of 6
James E. Minchin, Duke University, USA
Short Talk: Real-Time Imaging of Adipose Depot Morphogenesis in Zebrafish

Monday, January 25 | 5:00PM - 7:00PM
Molecular Programming of Hypothalamic Circuitry
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 1 of 5
* Kevin L. Grove, Novo Nordisk, USA


Monday, January 25 | 5:00PM - 7:00PM
Molecular Programming of Hypothalamic Circuitry
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 2 of 5
Joel K. Elmquist, University of Texas Southwestern Medical Center, USA
Cellular and Molecular Mechanisms Regulating Energy Balance and Glucose Homeostasis


Monday, January 25 | 5:00PM - 7:00PM
Molecular Programming of Hypothalamic Circuitry
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 3 of 5
Richard B. Simerly, Vanderbilt University, USA
Hormonal Specification of Hypothalamic Connectivity


Monday, January 25 | 5:00PM - 7:00PM
Molecular Programming of Hypothalamic Circuitry
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 4 of 5
Sadaf Farooqi, University of Cambridge, UK
Mutations of Hypothalamic Circuits in Humans


Monday, January 25 | 5:00PM - 7:00PM
Molecular Programming of Hypothalamic Circuitry
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 5 of 5
Yi-Chun Loraine Tung, University of Cambridge Metabolic Research Laboratories, UK
Short Talk: Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats


Monday, January 25 | 7:15PM - 8:00PM
Social Hour with Lite Bites
Room: Torreys 1-3, Shavano, Red Cloud


Monday, January 25 | 7:30PM - 10:00PM
Poster Session 1
Room: Torreys 1-3, Shavano, Red Cloud


Tuesday, January 26 | 7:00AM - 8:00AM
Breakfast
Room: Torreys 1-3, Shavano, Red Cloud


Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 1 of 7
* Sheila Collins, Vanderbilt University Medical Center, USA

Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 2 of 7
Jan Nedergaard, Stockholm University, Sweden
Human Brown Adipose Tissue presence and consequence

Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 3 of 7
Saverio Cinti, University of Ancona, Italy
The Adipose Organ

Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 4 of 7
Bruce M. Spiegelman, Harvard Medical School, USA
Obesity-Linked Phosphorylation of PPARgamma by cdk5 Causes Fat Cell Gene Dysregulation and Is a Direct Target of the Anti-Diabetic PPARgamma Ligand

Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 5 of 7
Karsten Kristiansen, University of Copenhagen, Denmark
Single Gene Mutations that Promote Brown Adipocyte Differentiation

Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 6 of 7
Marika Charalambous, Queen Mary University of London, UK
Short Talk: Impaired Thermogenesis and Persistent Hypothyroidism caused by Altered Dosage of Imprinted Genes

Tuesday, January 26 | 8:00AM - 11:15AM
Fat (R)evolution - The Brown vs. White Fat Debate
Room: Longs Peak

Speaker 7 of 7
Yu-Hua Tseng, Joslin Diabetes Center/Harvard Medical School, USA
Short Talk: Identification of Brown Fat Progenitors in Mouse Skeletal Muscle

Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 1 of 7
* Roger D. Cone, University of Michigan, USA


Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 2 of 7
Martin G. Myers, Jr., University of Michigan, USA
Neuromodulators of Leptin Action


Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 3 of 7
Michael A. Cowley, Monash University, Australia
Melanocortins and Glucose Homeostasis


Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 4 of 7
Michael Rosenbaum, Columbia University Medical College, USA
Leptin and Energy Homeostasis in Humans


Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 5 of 7
Tamas L. Horvath, Yale School of Medicine, USA
Fuel Utilization by Neurons: A Determinant of “Nutrient Sensing'


Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 6 of 7
Dong Kong, Tufts University School of Medicine, USA
Short Talk: Glucose Sensing by MCH Neurons Regulates Glucose Homeostasis and is Inhibited by UCP2


Tuesday, January 26 | 8:00AM - 11:15AM
Nutrient Sensing in the Brain
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 7 of 7
Hong Wang, University of Colorado Health Science Center, USA
Short Talk: Neuron-Specific Lipoprotein Lipase Deficiency Perturbs the Regulation of Energy Balance and Leads to Obesity by Modifying the Expression of the Orexigenic Neuropeptides AgRP and NPY


Tuesday, January 26 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, January 26 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Tuesday, January 26 | 11:15AM - 1:00PM
Poster Setup
Room: Torreys 1-3, Shavano, Red Cloud


Tuesday, January 26 | 1:00PM - 10:00PM
Poster Viewing
Room: Torreys 1-3, Shavano, Red Cloud


Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 1 of 9
* Sheila Collins, Vanderbilt University Medical Center, USA

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 2 of 9
Cristina M. Rondinone, Cellarity Inc., USA
Introductory 'In Memoriam' for Dean Londos

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 3 of 9
Chris E. Lowe, Horizon Discovery Ltd, UK
The ATF6alpha Pathway of the Unfolded Protein Response is Required for Adipogenesis

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 4 of 9
Ana G. Cristancho, University of Pennsylvania School of Medicine, USA
Transcription Factor 7-like 1 (TCF7L1) is required for PPARgamma2 Expression during Adipogenesis

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 5 of 9
Kai Ge, NIDDK, National Institutes of Health, USA
Epigenetic Regulation of Adipogenesis

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 6 of 9
Susanne Mandrup, University of Southern Denmark, Denmark
MED14 Tethers the Mediator to the N-Terminal Domain of PPARgamma and is Required for Full Transcriptional Activity and Adipogenesis

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 7 of 9
Charles Harris, Gladstone Institute for Cardiovascular Disease, USA
DGAT Enzymes Are Required for Triglyceride Synthesis and Lipid Droplet Formation But Not for Other Aspects of Adipogenesis

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 8 of 9
Cynthia Smas, University of Toledo, USA
Functional Analysis of FSP27 Protein Regions for Lipid Droplet Localization, Caspase-Dependent Apoptosis and Dimerization with CIDEA

Tuesday, January 26 | 2:30PM - 4:30PM
Workshop 1: New Aspects of Adipogenesis, Lipid Droplets and
Triglyceride Metabolism
Room: Grays/Longs Peaks

Speaker 9 of 9
† Lise Madsen, University of Copenhagen, Denmark
Transdifferentiation of White into Brown Adipose Tissue Requires Cyclooxygenases

Tuesday, January 26 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, January 26 | 5:00PM - 7:15PM
Insights from Model Organisms (Joint)
Room: Grays/Longs Peak

Speaker 1 of 6
* Karsten Kristiansen, University of Copenhagen, Denmark

Tuesday, January 26 | 5:00PM - 7:15PM
Insights from Model Organisms (Joint)
Room: Grays/Longs Peak

Speaker 2 of 6
Roger D. Cone, University of Michigan, USA
Biological Functions of AgRP and AgRP2 in Zebrafish

Tuesday, January 26 | 5:00PM - 7:15PM
Insights from Model Organisms (Joint)
Room: Grays/Longs Peak

Speaker 3 of 6
Sri Devi Narasimhan, Cell Press, USA
Identifying Phosphatases that Modulate the Insulin/IGF-1 Signaling Pathway

Tuesday, January 26 | 5:00PM - 7:15PM
Insights from Model Organisms (Joint)
Room: Grays/Longs Peak

Speaker 4 of 6
Sean M. Oldham, Takeda Pharmaceuticals International Co., USA
Role of Nutrient Sensing TOR Pathway in High Fat Diet-induced Signaling Pathway and aging

Tuesday, January 26 | 5:00PM - 7:15PM
Insights from Model Organisms (Joint)
Room: Grays/Longs Peak

Speaker 5 of 6
Biao Wang, The Salk Institute, USA
Short Talk: Drosophila Salt Inducible Kinase (SIK) in Fat Metabolism

Tuesday, January 26 | 5:00PM - 7:15PM
Insights from Model Organisms (Joint)
Room: Grays/Longs Peak

Speaker 6 of 6
Christine Hausen, Institute for Genetics, University of Cologne, Germany
Short Talk: Conserved Role for Insulin Receptor Signaling in Catecholaminergic Cells in Control of Energy Homeostasis

Tuesday, January 26 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Torreys 1-3, Shavano, Red Cloud


Tuesday, January 26 | 7:30PM - 10:00PM
Poster Session 2
Room: Torreys 1-3, Shavano, Red Cloud


Wednesday, January 27 | 7:00AM - 8:00AM
Breakfast
Room: Torreys 1-3, Shavano, Red Cloud


Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 1 of 7
* Randy J. Seeley, University of Michigan, USA

Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 2 of 7
Steven E. Shoelson, Harvard Medical School, Joslin Diabetes Center, USA
Obesity, Inflammation and Insulin Resistance (Basic and Clinical Issues)

Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 3 of 7
Ajay Chawla, Merck Research Labs, USA
Immune Regulation of Nutrient Metabolism and Aging

Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 4 of 7
Carey N. Lumeng, University of Michigan, USA
Short Talk: MGL1 Promotes Adipose Tissue Inflammation and Insulin Resistance by Regulating 7/4hi Monocytes in Obesity

Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 5 of 7
Umut Ozcan, Harvard Medical School, USA
The ER Stress and Leptin Resistance

Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 6 of 7
Daniel L. Marks, Oregon Health & Science University, USA
The Role of Central Melanocortin’s in Cachexia

Wednesday, January 27 | 8:00AM - 11:15AM
Immune Signals and Energy Homeostasis/Body Composition (Join
t)

Room: Grays/Longs Peak

Speaker 7 of 7
Jose M. Garcia, Baylor College of Medicine, USA
Short Talk: The Effects of Peripheral Ghrelin Administration on the Lipid Metabolism are Primarily Mediated through Changes in Food Intake in a Model of Cachexia

Wednesday, January 27 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, January 27 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Wednesday, January 27 | 11:15AM - 1:00PM
Poster Setup
Room: Torreys 1-3, Shavano, Red Cloud


Wednesday, January 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Torreys 1-3, Shavano, Red Cloud


Wednesday, January 27 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 1 of 7
John W. Newcomer, Washington University School of Medicine, USA

Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 2 of 7
* Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA

Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 3 of 7
Francesco Rubino, King's College London, UK
Resolution of Diabetes and Bariatric Surgery

Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 4 of 7
Paul O'Brien, Monash University, Australia
Appetite Control and Bariatric Surgery

Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 5 of 7
Randy J. Seeley, University of Michigan, USA
Bariatric Surgery: Beyond Restriction and Malabsorption

Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 6 of 7
Thomas Alexander Lutz, University of Zürich, Switzerland
Short Talk: Roux-en-Y Gastric Bypass Increases Energy Expenditure Affects Taste Preference and Impairs Bone Structure Rats

Wednesday, January 27 | 5:00PM - 7:00PM
Bariatric Surgery and the Treatment of Metabolic Disease
Room: Longs Peak

Speaker 7 of 7
Jocelyne Magré, INSERM, France
Genetics of Congenital Generalized Lipodystrophy

Wednesday, January 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Torreys 1-3, Shavano, Red Cloud


Wednesday, January 27 | 7:30PM - 10:00PM
Poster Session 3
Room: Torreys 1-3, Shavano, Red Cloud


Thursday, January 28 | 7:00AM - 8:00AM
Breakfast
Room: Torreys 1-3, Shavano, Red Cloud


Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 1 of 7
* Barbara Cannon, Stockholm University, Sweden

Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 2 of 7
Hei Sook Sul, University of California, Berkeley, USA
Pref-1: Role in Adipogenesis and Mesenchymal Cell Fate

Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 3 of 7
Rei Ogawa, Nippon Medical School, Japan
Application of Adipose Stem Cells for Plastic Surgery - In Particular about Cartilage Regeneration


Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 4 of 7
Ormond A. MacDougald, University of Michigan, USA
Role of Wnt Signaling in the Regulation of Adipocyte Differentiation

Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 5 of 7
Zoubir E. Amri, INSERM U470, France
Short Talk: Human Multipotent Adipose-Derived Stem Cells Differentiate into Functional Brown Adipocytes

Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 6 of 7
Daniel R. Zeve, University of Texas Southwestern Medical Center at Dallas, USA
Short Talk: Defining Developmentally Important Genes within the White Adipose Progenitor Cells

Thursday, January 28 | 8:00AM - 11:15AM
Adipose Stem Cells: Biology and Application (Bone Marrow vs.
Adipose Tissue; Characteristics/Signaling that Promote their Differentiation; Plastics/Reconstructive, Tissue Engineering Aspects)

Room: Longs Peak

Speaker 7 of 7
Maryam Ahmadian, The Salk Institute, USA
Short Talk: Adipose-Specific Phospholipase A2 (AdPLA) Ablation Prevents Diet-Induced and Genetic Obesity: A Novel Lipodystrophy Model

Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 1 of 7
* Daniel L. Marks, Oregon Health & Science University, USA


Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 2 of 7
Marta Korbonits, Barts and The London, Queen Mary's School of Medicine and Dentistry, UK
Cross-Talk of Endocannabinoids and Ghrelin


Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 3 of 7
Darren Opland, University of Michigan, USA
Short Talk: VTA Leptin Receptor Neurons Specifically Project to and Regulate CART Neurons of the Extended Central Amygdala


Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 4 of 7
Alastair V. Ferguson, Queen's University, Canada
Sensory Circumventricular Organs: Integrative Control Centers Regulating Energy Balance?


Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 5 of 7
Hans Rudolf Berthoud, Pennington Biomedical Research Center, USA
Hedonic, Emotional, Cognitive, and Metabolic Controls of Appetite and Energy Balance: Who is The Boss?


Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 6 of 7
Lora K. Heisler, Rowett Institute, University of Aberdeen, UK
Serotonin Influences Melanocortin Pathways to Affect Energy Balance


Thursday, January 28 | 8:00AM - 11:15AM
Thinking Outside of the Hypothalamus
This session is from Neuronal Control of Appetite
Room: Grays Peak

Speaker 7 of 7
Matthew R. Hayes, University of Pennsylvania, USA
Short Talk: Endogenous Leptin Signaling in the NTS is Required for Energy Balance Regulation


Thursday, January 28 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, January 28 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Thursday, January 28 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, January 28 | 5:00PM - 7:15PM
Drug Development: Treating the Brain and Beyond (Joint)
Room: Grays/Longs Peaks

Speaker 1 of 6
* Michael A. Cowley, Monash University, Australia

Thursday, January 28 | 5:00PM - 7:15PM
Drug Development: Treating the Brain and Beyond (Joint)
Room: Grays/Longs Peaks

Speaker 2 of 6
Eduardo Dunayevich, Amgen, USA
The Combination of Bupropion and Naltrexone in the Treatment of Obesity: From Bench to Pivotal Trials

Thursday, January 28 | 5:00PM - 7:15PM
Drug Development: Treating the Brain and Beyond (Joint)
Room: Grays/Longs Peaks

Speaker 3 of 6
Donald J. Marsh, Merck Research Laboratories, USA
New Neuropeptide Target Systems: Neuromedin U

Thursday, January 28 | 5:00PM - 7:15PM
Drug Development: Treating the Brain and Beyond (Joint)
Room: Grays/Longs Peaks

Speaker 4 of 6
Michael Culler, Ipsen/Biomeasure, USA
Novel Peptide Ligands of the Melanocortin Type 4 Receptor for the Treatment of Obesity and Metabolic Disease

Thursday, January 28 | 5:00PM - 7:15PM
Drug Development: Treating the Brain and Beyond (Joint)
Room: Grays/Longs Peaks

Speaker 5 of 6
Lee M. Kaplan, Massachusetts General Hospital, USA
Short Talk: Roux-en-Y Bypass Stimulates BAT Activity and Central Control Thermogenesis in Mice

Thursday, January 28 | 5:00PM - 7:15PM
Drug Development: Treating the Brain and Beyond (Joint)
Room: Grays/Longs Peaks

Speaker 6 of 6
Alan Koncarevic, Acceleron Pharma, USA
Short Talk: Induction of a Thermogenic Program in White Adipose Tissue of HFD-Fed Mice Treated with a Soluble ActRIIB

Thursday, January 28 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Torreys 1-3, Shavano, Red Cloud


Thursday, January 28 | 8:00PM - 11:00PM
Entertainment
Room: Torreys 1-3, Shavano, Red Cloud


Thursday, January 28 | 8:00PM - 11:00PM
Cash Bar
Room: Torreys 1-3, Shavano, Red Cloud


Friday, January 29 | 10:25AM - 10:25AM
Departure


*Session Chair.