Web Desc
Advances in Molecular Mechanisms of Atherosclerosis
joint with The Macrophage: Intersection of Pathogenic and Protective Inflammation
Organizer(s): Russell A. DeBose-Boyd and Christopher K. Glass
Date: February 12 - 17, 2010
Location: Fairmont Banff Springs, Banff, AB, Canada
Supported by The Directors' Fund
Summary of Meeting:
Atherosclerosis, a disease that affects arterial blood vessels, is the major cause of death in developed countries and emerging economies worldwide. The disease is initiated when cholesterol-rich low-density lipoproteins adhere to the walls of arteries, triggering a complex set of reactions involving a variety of cell types including macrophages, endothelial cells, smooth muscle cells, and lymphocytes. This initial lesion progresses to a more complicated atherosclerotic plaque through subsequent cell-cell and cell-lipid interactions that cause chronic inflammation, extracellular alterations, and necrosis. These responses promote plaque disruption, which triggers acute thrombosis resulting in vascular occlusion and myocardial infarction. The goal of this meeting is to provide attendees with the latest advances in the understanding of cellular processes that contribute to atherosclerosis, with particular emphasis on cholesterol metabolism and foam cell formation, genetics, and the immune system. These goals will be significantly enhanced by holding the meeting concurrently with the meeting, The Macrophage: Intersection of Pathogenic and Protective Inflammation. In addition to four atherosclerosis-specific plenary sessions, four joint sessions are planned to highlight major developments in areas of mutual interest to investigators in the fields of atherosclerosis and macrophage biology. Elucidation of mechanisms underlying development of atherosclerosis may reveal new therapeutic strategies to combat the disease. This program will stimulate interactions that are likely to augment and accelerate this process.
Scholarship Deadline: October 12 2009
Discounted Abstract Deadline: October 12 2009
Abstract Deadline: November 13 2009
Discounted Registration Deadline: December 14 2009
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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Program

Friday, February 12 | 3:00PM - 7:30PM
Registration
Room: Van Horne Foyer


Friday, February 12 | 6:30PM - 7:30PM
Refreshments
Room: Van Horne Foyer


Friday, February 12 | 7:30PM - 8:30PM
Keynote Address (Joint)
Room: Van Horne Ballroom A-B

Speaker 1 of 1
Carl F. Nathan, Weill Cornell Medical College, USA
Non-Resolving Inflammation: Disease, Defense and Therapy

Saturday, February 13 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Saturday, February 13 | 8:00AM - 11:15AM
Genetics and Functional Genomics of Atherosclerosis
Room: Van Horne Ballroom C

Speaker 1 of 6
Sekar Kathiresan, Verve Therapeutics, USA
Mapping Genes for Plasma Lipids and Myocardial Infarction in Humans

Saturday, February 13 | 8:00AM - 11:15AM
Genetics and Functional Genomics of Atherosclerosis
Room: Van Horne Ballroom C

Speaker 2 of 6
Eric Schadt, Mount Sinai School of Medicine, USA
Moving Toward a Systems Biology Understanding of Complex Human Diseases

Saturday, February 13 | 8:00AM - 11:15AM
Genetics and Functional Genomics of Atherosclerosis
Room: Van Horne Ballroom C

Speaker 3 of 6
Karen Reue, University of California, Los Angeles, USA
Identification of Novel Lipid Metabolism Genes from Spontaneous Mouse Mutants

Saturday, February 13 | 8:00AM - 11:15AM
Genetics and Functional Genomics of Atherosclerosis
Room: Van Horne Ballroom C

Speaker 4 of 6
* Daniel J. Rader, University of Pennsylvania, USA
Functional Characterization of Novel Loci Associated with Plasma Lipids

Saturday, February 13 | 8:00AM - 11:15AM
Genetics and Functional Genomics of Atherosclerosis
Room: Van Horne Ballroom C

Speaker 5 of 6
Yajaira Suárez, New York University School of Medicine, USA
Short Talk: TNF-Induced microRNAs Regulate TNF-Induce Expression of E-Selectin and ICAM-1 in Human Endothelial Cells

Saturday, February 13 | 8:00AM - 11:15AM
Genetics and Functional Genomics of Atherosclerosis
Room: Van Horne Ballroom C

Speaker 6 of 6
Johan Lars Markus Björkegren, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Multi-Organ Expression Profiling to Uncover Gene Networks and Modules of Importance to Coronary Artery Disease

Saturday, February 13 | 8:00AM - 11:00AM
Macrophages and Pathogens I
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 1 of 5
* De' Broski R. Herbert, University of Pennsylvania, USA


Saturday, February 13 | 8:00AM - 11:00AM
Macrophages and Pathogens I
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 2 of 5
Lalita Ramakrishnan, University of Cambridge, UK
An Eicosanoid Pathway Rheostat Controls Susceptibility to Mycobacteria in Zebrafish and Humans


Saturday, February 13 | 8:00AM - 11:00AM
Macrophages and Pathogens I
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Nod-like receptors: Role in immunity and inflammatory diseases


Saturday, February 13 | 8:00AM - 11:00AM
Macrophages and Pathogens I
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 4 of 5
Sabine Ehrt, Weill Cornell Medical College, USA
Mycobacterial Survival Strategies in the Macrophage Phagosome


Saturday, February 13 | 8:00AM - 11:00AM
Macrophages and Pathogens I
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 5 of 5
Alan Sher, NIAID, National Institutes of Health, USA
Poly-IC Treatment Exacerbates Tuberculosis by the Pulmonary Recruitment of a Pathogen-permissive Monocyte/macrophage Population


Saturday, February 13 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Saturday, February 13 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Saturday, February 13 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Saturday, February 13 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Saturday, February 13 | 2:30PM - 4:30PM
Workshop 1
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 1 of 6
* Lalita Ramakrishnan, University of Cambridge, UK


Saturday, February 13 | 2:30PM - 4:30PM
Workshop 1
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 2 of 6
Jennifer Philips, Washington University School of Medicine, USA
Functional Genomics of the Host: Defining Macrophage Susceptibility to Mycobacterial Infection


Saturday, February 13 | 2:30PM - 4:30PM
Workshop 1
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 3 of 6
Dennis Montoya, University of California, Los Angeles, USA
Plasticity of Macrophage Phagocytic and Antimicrobial Programs in Leprosy


Saturday, February 13 | 2:30PM - 4:30PM
Workshop 1
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 4 of 6
Hanne Gunda Schoenen, Institute for Clinical Microbiology and Hygiene, Germany
Mincle is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analogue Trehalose-Dibehenate1


Saturday, February 13 | 2:30PM - 4:30PM
Workshop 1
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 5 of 6
Antoine Tinel, Harvard Medical School, USA
A Crucial Role for SIRT1 in Host-Defense Mechanisms


Saturday, February 13 | 2:30PM - 4:30PM
Workshop 1
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 6 of 6
Sandra E. Nicholson, Walter and Eliza Hall Institute of Medical Research, Australia
The SPRY Domain-containing SOCS Box Protein SPSB2 Targets iNOS for Ubiquitination and Proteasomal Degradation


Saturday, February 13 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Saturday, February 13 | 5:00PM - 7:15PM
Signaling and Gene Expression (Joint)
Room: Van Horne Ballroom A-B

Speaker 1 of 5
* Linda K. Curtiss, The Scripps Research Institute, USA
Atherosclerosis: An Unfortunate Mix of Lipids and Inflammation Whipped Up by Toll-Like Receptors

Saturday, February 13 | 5:00PM - 7:15PM
Signaling and Gene Expression (Joint)
Room: Van Horne Ballroom A-B

Speaker 2 of 5
Joachim Herz, University of Texas Southwestern Medical Center, USA
Importance of Cholesterol Homeostasis in Vascular Smooth Muscle Cells

Saturday, February 13 | 5:00PM - 7:15PM
Signaling and Gene Expression (Joint)
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Petra Keul, University of Duisburg, Essen, Germany
Short Talk: Deletion of the S1P Receptor S1P3 Attenuates Macrophage-Driven Inflammation in Atherosclerotic Lesions of S1P3-/-/ApoE -/- Double Knockout Mice

Saturday, February 13 | 5:00PM - 7:15PM
Signaling and Gene Expression (Joint)
Room: Van Horne Ballroom A-B

Speaker 4 of 5
Jay W. Heinecke, University of Washington School of Medicine, USA
Short Talk: Defining the Proteome of the Macrophage Foam Cell

Saturday, February 13 | 5:00PM - 7:15PM
Signaling and Gene Expression (Joint)
Room: Van Horne Ballroom A-B

Speaker 5 of 5
Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA
Regulation of Inflammatory Gene Expression in Macrophages

Saturday, February 13 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Mezzanine 2


Saturday, February 13 | 7:30PM - 10:00PM
Poster Session 1
Room: Mezzanine 2


Sunday, February 14 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Sunday, February 14 | 8:00AM - 11:15AM
Immune Mechanisms and Atherosclerosis
Room: Van Horne Ballroom C

Speaker 1 of 6
Göran K. Hansson, Karolinska University Hospital, Sweden
Interplay of Innate and Adaptive Immune Mechanisms in Atherosclerosis

Sunday, February 14 | 8:00AM - 11:15AM
Immune Mechanisms and Atherosclerosis
Room: Van Horne Ballroom C

Speaker 2 of 6
* Joseph L. Witztum, University of California, San Diego, USA
Oxidation-Specific Epitopes are a Major Target of Innate Immunity

Sunday, February 14 | 8:00AM - 11:15AM
Immune Mechanisms and Atherosclerosis
Room: Van Horne Ballroom C

Speaker 3 of 6
Ziad Mallat, University of Cambridge, UK
Regulatory T Cell Immunity in Atherosclerosis

Sunday, February 14 | 8:00AM - 11:15AM
Immune Mechanisms and Atherosclerosis
Room: Van Horne Ballroom C

Speaker 4 of 6
Gwendalyn J. Randolph, Washington University, USA
Fate of Monocyte-Derived Cells in Atherosclerotic Plaques versus Sites of Resolving Inflammation

Sunday, February 14 | 8:00AM - 11:15AM
Immune Mechanisms and Atherosclerosis
Room: Van Horne Ballroom C

Speaker 5 of 6
David Weismann, Center for Molecular Medicine of the Austrian Academy of Sciences, Austria
Short Talk: Discovery of a novel malondialdehyde (MDA) binding protein

Sunday, February 14 | 8:00AM - 11:15AM
Immune Mechanisms and Atherosclerosis
Room: Van Horne Ballroom C

Speaker 6 of 6
Yue Zhao, Vanderbilt University, USA
Short Talk: The NR4A Orphan Nuclear Receptor NOR1 Mediates Monocyte Adhesion and Atherosclerosis Formation in Mice

Sunday, February 14 | 8:00AM - 11:00AM
Understanding Human Macrophages
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 1 of 6
* Peter J. Murray, Max-Planck-Institut für Biochemie, Germany


Sunday, February 14 | 8:00AM - 11:00AM
Understanding Human Macrophages
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 2 of 6
Lionel B. Ivashkiv, Hospital for Special Surgery, New York, USA
Signal Integration during Macrophage Activation and Cytokine Production


Sunday, February 14 | 8:00AM - 11:00AM
Understanding Human Macrophages
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 3 of 6
David A. Hume, University of Edinburgh, UK
Transcriptional Networks in Macrophage Differentiation and Activation


Sunday, February 14 | 8:00AM - 11:00AM
Understanding Human Macrophages
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 4 of 6
Menno Van Lookeren Campagne, Genentech, Inc., USA
A Central Role for Complement and Liver Kupffer Cells in Host Defense


Sunday, February 14 | 8:00AM - 11:00AM
Understanding Human Macrophages
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 5 of 6
Christopher L. Karp, Bill & Melinda Gates Foundation, USA
Pathogen Contact with Human Macrophages


Sunday, February 14 | 8:00AM - 11:00AM
Understanding Human Macrophages
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 6 of 6
Molly Ingersoll, Institut Pasteur, France
Short Talk: Comparison of Gene Expression Profiles between Human and Mouse Monocyte Subsets


Sunday, February 14 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Sunday, February 14 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Sunday, February 14 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Sunday, February 14 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Sunday, February 14 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Sunday, February 14 | 5:00PM - 7:00PM
Macrophage Movement (Joint)
Room: Van Horne Ballroom A-B

Speaker 1 of 5
* Gerald Krystal, British Columbia Cancer Research Centre, Canada

Sunday, February 14 | 5:00PM - 7:00PM
Macrophage Movement (Joint)
Room: Van Horne Ballroom A-B

Speaker 2 of 5
Israel F. Charo, ChemoCentryx, Inc., USA
CCR2 in atherosclerosis, insulin resistance, and hematopoietic stem cell trafficking

Sunday, February 14 | 5:00PM - 7:00PM
Macrophage Movement (Joint)
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Frederic Geissmann, Memorial Sloan Kettering Cancer Center, USA
Function of the mononuclear phagocyte system: In vivo in human and model organisms

Sunday, February 14 | 5:00PM - 7:00PM
Macrophage Movement (Joint)
Room: Van Horne Ballroom A-B

Speaker 4 of 5
Steven L. Kunkel, University of Michigan Medical School, USA
Writers, Readers, and Erasers: Dynamic Epigenetic Regulation of the Macrophage Phenotype

Sunday, February 14 | 5:00PM - 7:00PM
Macrophage Movement (Joint)
Room: Van Horne Ballroom A-B

Speaker 5 of 5
Andrea L. Hevener, University of California, Los Angeles, USA
Short Talk: Myeloid-specific Deletion of Estrogen Receptor-alpha (ERalpha) Promotes Obesity and Insulin Resistance in Mice

Sunday, February 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2


Sunday, February 14 | 7:30PM - 10:00PM
Poster Session 2
Room: Mezzanine 2


Monday, February 15 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Monday, February 15 | 8:00AM - 11:15AM
The Vulnerable Plaque
Room: Van Horne Ballroom C

Speaker 1 of 6
Philippe Boucher, University of Strasbourg, France
PPAR-gamma Inhibits Vascular Calcification by Controlling an LRP1/beta-Catenin Signaling Pathway

Monday, February 15 | 8:00AM - 11:15AM
The Vulnerable Plaque
Room: Van Horne Ballroom C

Speaker 2 of 6
Peter Libby, Brigham and Women's Hospital, USA
Extracellular Matrix Metabolism and Determinants of Plaque Stability

Monday, February 15 | 8:00AM - 11:15AM
The Vulnerable Plaque
Room: Van Horne Ballroom C

Speaker 3 of 6
Garret A. FitzGerald, University of Pennsylvania, USA
Cardiovascular Complexity in the Prostanoid System

Monday, February 15 | 8:00AM - 11:15AM
The Vulnerable Plaque
Room: Van Horne Ballroom C

Speaker 4 of 6
* Ira Tabas, Columbia University, USA
Mechanisms and Consequences of Macrophage Apoptosis in Atherosclerosis

Monday, February 15 | 8:00AM - 11:15AM
The Vulnerable Plaque
Room: Van Horne Ballroom C

Speaker 5 of 6
Kristiina Satu Susanna Rajamäki, Wihuri Research Institute, Finland
Short Talk: Cholesterol Crystals Activate Inflammasome Signaling in Human Macrophages

Monday, February 15 | 8:00AM - 11:15AM
The Vulnerable Plaque
Room: Van Horne Ballroom C

Speaker 6 of 6
Walter S. Speidl, Medical University of Vienna, Austria
Short Talk: The Complement Component C5a Induces the Expression of MMP-1 and MMP-9 in Human Macrophages

Monday, February 15 | 8:00AM - 11:00AM
Sterile Inflammation and Cancer Inflammation
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 1 of 6
* Christopher L. Karp, Bill & Melinda Gates Foundation, USA


Monday, February 15 | 8:00AM - 11:00AM
Sterile Inflammation and Cancer Inflammation
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 2 of 6
Kenneth L. Rock, University of Massachusetts Medical School, USA
The Sterile Inflammatory Response


Monday, February 15 | 8:00AM - 11:00AM
Sterile Inflammation and Cancer Inflammation
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 3 of 6
Vincenzo Bronte, University of Verona, Italy
Myeloid-Derived Suppressor Cells


Monday, February 15 | 8:00AM - 11:00AM
Sterile Inflammation and Cancer Inflammation
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 4 of 6
Thorsten Hagemann, Barts and The London Queen Mary's Medical School, UK
Cancer-Related Inflammation


Monday, February 15 | 8:00AM - 11:00AM
Sterile Inflammation and Cancer Inflammation
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 5 of 6
Shigekazu Nagata, IFReC, Osaka University, Japan
Engulfment and degradation of apoptotic cells


Monday, February 15 | 8:00AM - 11:00AM
Sterile Inflammation and Cancer Inflammation
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 6 of 6
Antonio Castrillo, Instituto Investigaciones Biomedicas CSIC, Spain
Short Talk: LXR Nuclear Receptors Regulate Apoptotic Cell Clearance and Immune Tolerance


Monday, February 15 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Monday, February 15 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Monday, February 15 | 11:15AM - 1:00PM
Poster Setup
Room: Mezzanine 2


Monday, February 15 | 1:00PM - 10:00PM
Poster Viewing
Room: Mezzanine 2


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 1 of 9
* Steven L. Kunkel, University of Michigan Medical School, USA


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 2 of 9
Jan Van den Bossche, Amsterdam UMC VUmc, Netherlands
Alternatively Activated Macrophages Engage in Homotypic and Heterotypic Interactions through IL-4 and Polyamine-Induced E Cadherin/Catenin Complexes


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 3 of 9
Mark Gilchrist, Seattle BioMed, USA
Sumo 1 Modification and Regulation of the Transcription Factor ATF3 in Macrophages


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 4 of 9
Karin Reif, Genentech, Inc., USA
A Novel Highly Specific Small Molecule Inhibitor for BTK Suppresses Fc Receptor Function in Macrophages and Prevents Inflammatory Arthritis


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 5 of 9
Jacob Rachmilewitz, Goldyn Savad Institute for Gene Therapy, Israel
Cells Exposed to Sub-Lethal Oxidative-Stress Attract Monocytes via a MYD88-Linked Receptor but do not Provoke the Release of Pro-Inflammatory Cytokines


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 6 of 9
Jessica A. Hamerman, Benaroya Research Institute, USA
ITAM Signaling Adapters Regulate Macrophage and Dendritic Cell Function and Homeostasis


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 7 of 9
Amrom Obstfeld, Columbia University, USA
Obesity Induced Hepatic Myeloid Cells Modulate Liver Steatosis


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 8 of 9
Suneil K. Koliwad, University of California, San Francisco, USA
Macrophage Triacylglycerol Storage as a Modulator of the Inflammatory and Metabolic Response to Dietary Fats


Monday, February 15 | 2:30PM - 4:30PM
Workshop 2
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 9 of 9
Pavel Kovarik, University of Vienna, Austria
Qualitative and Temporal Control of mRNA Decay during Inflammatory Response of Macrophages


Monday, February 15 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Monday, February 15 | 5:00PM - 7:00PM
Deactivating Macrophage Activity (Joint)
Room: Van Horne Ballroom A-B

Speaker 1 of 4
Peter J. Murray, Max-Planck-Institut für Biochemie, Germany
Cytokine-Mediated Deactivation of the Activated Macrophage

Monday, February 15 | 5:00PM - 7:00PM
Deactivating Macrophage Activity (Joint)
Room: Van Horne Ballroom A-B

Speaker 2 of 4
Gerald Krystal, British Columbia Cancer Research Centre, Canada
The Role of SHIP in Macrophage Skewing and Activation

Monday, February 15 | 5:00PM - 7:00PM
Deactivating Macrophage Activity (Joint)
Room: Van Horne Ballroom A-B

Speaker 3 of 4
* Christopher K. Glass, University of California, San Diego, USA
Nuclear Receptor Repression Pathways that Regulate Inflammation

Monday, February 15 | 5:00PM - 7:00PM
Deactivating Macrophage Activity (Joint)
Room: Van Horne Ballroom A-B

Speaker 4 of 4
Tim Ian Smallie, Kennedy Institute of Rheumatology Division, UK
Short Talk: IL-10 Negatively Regulates Macrophage Activation by Inhibiting Transcription Elongation

Monday, February 15 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2


Monday, February 15 | 7:30PM - 10:00PM
Poster Session 3
Room: Mezzanine 2


Tuesday, February 16 | 7:00AM - 8:00AM
Breakfast
Room: Mezzanine 2


Tuesday, February 16 | 8:00AM - 11:15AM
Cholesterol Homeostasis/Foam Cell Formation
Room: Van Horne Ballroom C

Speaker 1 of 6
* Russell A. DeBose-Boyd, University of Texas Southwestern Medical Center, USA
Cholesterol Homeostasis and Sterol-Accelerated Degradation of HMG CoA Reductase

Tuesday, February 16 | 8:00AM - 11:15AM
Cholesterol Homeostasis/Foam Cell Formation
Room: Van Horne Ballroom C

Speaker 2 of 6
Alan R. Tall, Columbia University, USA
HDL, ABC Transporters and Atherosclerosis

Tuesday, February 16 | 8:00AM - 11:15AM
Cholesterol Homeostasis/Foam Cell Formation
Room: Van Horne Ballroom C

Speaker 3 of 6
Kathryn J. Moore, New York University Medical Center, USA
Micro-Managing Macrophage Cholesterol Metabolism

Tuesday, February 16 | 8:00AM - 11:15AM
Cholesterol Homeostasis/Foam Cell Formation
Room: Van Horne Ballroom C

Speaker 4 of 6
Edward A. Fisher, New York University School of Medicine, USA
HDL and Atherosclerosis Regression: Effects on the Quantity and Quality of Monocyte-Derived Cells in Plaques

Tuesday, February 16 | 8:00AM - 11:15AM
Cholesterol Homeostasis/Foam Cell Formation
Room: Van Horne Ballroom C

Speaker 5 of 6
Prakash Gopaldas Chandak, Institute of Molecular Biology and Biochemistry, Austria
Short Talk: Adipose Triglyceride Lipase Deficiency Affects Macrophage Morphology and Function and Significantly Reduces Atherosclerosis in LDLR -/- Mice

Tuesday, February 16 | 8:00AM - 11:15AM
Cholesterol Homeostasis/Foam Cell Formation
Room: Van Horne Ballroom C

Speaker 6 of 6
Shunxing Rong, Wake Forest University School of Medicine, USA
Short Talk: High Polyunsaturated fatty acid (PUFA) diet unmasks role of 12/15 lipoxygenase in lipid metabolism

Tuesday, February 16 | 8:00AM - 11:00AM
Macrophage and Pathogens II
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 1 of 5
* Sabine Ehrt, Weill Cornell Medical College, USA


Tuesday, February 16 | 8:00AM - 11:00AM
Macrophage and Pathogens II
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 2 of 5
De' Broski R. Herbert, University of Pennsylvania, USA
Alternatively Activated Macrophages Control Helminth-Driven Immunopathology


Tuesday, February 16 | 8:00AM - 11:00AM
Macrophage and Pathogens II
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 3 of 5
Thomas A. Wynn, Pfizer, USA
The Role of IL-4/IL-13 Activated Macrophages in Fibrosis


Tuesday, February 16 | 8:00AM - 11:00AM
Macrophage and Pathogens II
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 4 of 5
Judith E. Allen, University of Manchester, UK
The Macrophage and the Worm


Tuesday, February 16 | 8:00AM - 11:00AM
Macrophage and Pathogens II
This session is from Macrophages
Room: Van Horne Ballroom A-B

Speaker 5 of 5
Sara R. Cherry, University of Pennsylvania, USA
Using high-throughput screening to identify cell-intrinsic innate immune pathways


Tuesday, February 16 | 9:20AM - 9:40AM
Coffee Break
Room: Van Horne Foyer


Tuesday, February 16 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Tuesday, February 16 | 4:30PM - 5:00PM
Coffee Available
Room: Van Horne Foyer


Tuesday, February 16 | 5:00PM - 7:00PM
Metabolism and Macrophages at the Intersection of Metabolic
Control (Joint)

Room: Van Horne Ballroom A-B

Speaker 1 of 5
* Russell A. DeBose-Boyd, University of Texas Southwestern Medical Center, USA

Tuesday, February 16 | 5:00PM - 7:00PM
Metabolism and Macrophages at the Intersection of Metabolic
Control (Joint)

Room: Van Horne Ballroom A-B

Speaker 2 of 5
* Ajay Chawla, Merck Research Labs, USA
Immune regulation of nutrient metabolism and aging

Tuesday, February 16 | 5:00PM - 7:00PM
Metabolism and Macrophages at the Intersection of Metabolic
Control (Joint)

Room: Van Horne Ballroom A-B

Speaker 3 of 5
William A. Muller, Northwestern University, USA
All Roads Lead to the LBRC: A common mechanism for leukocyte transendothelial migration

Tuesday, February 16 | 5:00PM - 7:00PM
Metabolism and Macrophages at the Intersection of Metabolic
Control (Joint)

Room: Van Horne Ballroom A-B

Speaker 4 of 5
Ebru Erbay, Bilkent University, Turkey
The Role of Endoplasmic Reticulum Stress in Atherosclerosis and its Regulation by Lipids

Tuesday, February 16 | 5:00PM - 7:00PM
Metabolism and Macrophages at the Intersection of Metabolic
Control (Joint)

Room: Van Horne Ballroom A-B

Speaker 5 of 5
Hwee Ying Lim, National University of Singapore, Singapore
Short Talk: Ezetimibe Restores lymphatic vessel function and dendritic cell migration, in hypercholesterolemic apoE deficient mice

Tuesday, February 16 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Mezzanine 2


Tuesday, February 16 | 8:00PM - 11:00PM
Entertainment
Room: Mezzanine 2


Tuesday, February 16 | 8:00PM - 11:00PM
Cash Bar
Room: Mezzanine 2


Wednesday, February 17 | 10:25AM - 10:25AM
Departure


*Session Chair.