Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Nuclear Receptors: Full Throttle (2016J1)
Nuclear Receptors: Biological Networks, Genome Dynamics and Disease (2014A3)
Nuclear Receptor Matrix: Reloaded (2012D3)

Web Desc
Nuclear Receptors: Development, Physiology and Disease joint with Nuclear Receptors: Signaling, Gene Regulation and Cancer Organizer(s): Carl S. Thummel, David D. Moore and Joyce J. Repa Date: March 21 - 26, 2010 Location: Keystone Resort, Keystone, CO, USA Supported by The Directors' Fund For important information on the coronavirus, please click here Summary of Meeting: Nuclear receptors represent a family of ligand-regulated transcription factors that play central roles in development, physiology, and metabolism. Upon binding small lipophilic hormones and metabolites, such as steroids, fatty acids, and bile acids, nuclear receptors switch their regulatory status, reprogramming gene expression in target tissues. Current research is aimed at defining roles for these receptors in normal development and metabolism as well as better understanding how nuclear receptor dysfunction contributes to diabetes, cancer, cardiovascular disease, obesity, and neuronal disorders. Nuclear receptors are also a major target for drug development, with many compounds on the market and several in ongoing human trials. This meeting will highlight recent breakthroughs in nuclear receptor research, promote interactions between scientists from industry and academia, and provide opportunities for senior scientists to interact with younger researchers and trainees. Scholarship Deadline: November 23 2009 Discounted Abstract Deadline: November 23 2009 Abstract Deadline: December 28 2009 Discounted Registration Deadline: January 22 2010 We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Merck & Co., Inc. We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 1R13DK084688-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Nuclear Receptors: Development, Physiology and Disease

joint with Nuclear Receptors: Signaling, Gene Regulation and Cancer

Organizer(s): Carl S. Thummel, David D. Moore and Joyce J. Repa

Date: March 21 - 26, 2010
Location: Keystone Resort, Keystone, CO, USA

Supported by The Directors' Fund

For important information on the coronavirus, please click here

Summary of Meeting:

Nuclear receptors represent a family of ligand-regulated transcription factors that play central roles in development, physiology, and metabolism. Upon binding small lipophilic hormones and metabolites, such as steroids, fatty acids, and bile acids, nuclear receptors switch their regulatory status, reprogramming gene expression in target tissues. Current research is aimed at defining roles for these receptors in normal development and metabolism as well as better understanding how nuclear receptor dysfunction contributes to diabetes, cancer, cardiovascular disease, obesity, and neuronal disorders. Nuclear receptors are also a major target for drug development, with many compounds on the market and several in ongoing human trials. This meeting will highlight recent breakthroughs in nuclear receptor research, promote interactions between scientists from industry and academia, and provide opportunities for senior scientists to interact with younger researchers and trainees.

Scholarship Deadline: November 23 2009

Discounted Abstract Deadline: November 23 2009

Abstract Deadline: December 28 2009

Discounted Registration Deadline: January 22 2010

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Merck & Co., Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK084688-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 21 \| 3:00PM - 7:30PM Registration Room: Longs Peak Foyer
Sunday, March 21 \| 6:30PM - 7:30PM Refreshments Room: Longs Peak Foyer
Sunday, March 21 \| 7:30PM - 8:30PM Keynote Address (Joint) Room: Grays/Longs Peaks Speaker 1 of 1 Gideon Dreyfuss, HHMI/University of Pennsylvania School of Medicine, USA RNA-Protein Complexes (RNPs): The Instruments of Post-Transcriptional Gene Regulation
Monday, March 22 \| 7:00AM - 8:00AM Breakfast Room: Shavano/Torreys
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 1 of 7 * Carl S. Thummel, University of Utah School of Medicine, USA
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 2 of 7 Peter Tontonoz, University of California, Los Angeles, USA Liver X Receptors in Metabolism, Inflammation and Disease
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 3 of 7 Carlie J. M. de Vries, University of Amsterdam, Netherlands NR4A Orphan Nuclear Receptors in Vascular Disease
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 4 of 7 Joe Thornton, University of Chicago, USA Evolution of Nuclear Receptors
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 5 of 7 Henry M. Krause, University of Toronto, Canada Coordination of Developmental Check Points and Metabolism
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 6 of 7 Jason M. Tennessen, Indiana University, USA Short Talk: The Drosophila Estrogen-Related Receptor Coordinates Carbohydrate Metabolism with Cell Growth
Monday, March 22 \| 8:00AM - 11:15AM Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 7 of 7 Marc R. Van Gilst, Fred Hutchinson Cancer Research Center, USA Short Talk: From the Nematode Nuclear Receptor Milieu, C. elegans NHR-49 Emerges as a Casanova
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 7 * Kathryn B. Horwitz, University of Colorado Health Sciences Center, USA
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 7 Carole R. Mendelson, University of Texas Southwestern Medical Center, USA Mechanisms in Progesterone Receptor Regulation of Inflammatory Signaling in Pregnancy and Labor
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 7 Sheue-Yann Cheng, NCI, National Institutes of Health, USA Novel Signaling of Mutant Thyroid Hormone Receptors in Carcinogenesis
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 7 John A. Cidlowski, NIEHS, National Institutes of Health, USA Talk Title to be Determined
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 7 Iris Z. Jaffe, Tufts-New England Medical Center, USA Mineralocorticoid Receptor Regulation of Vascular Gene Expression: Role in Vascular Function and Disease
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 7 Jennifer K. Richer, University of Colorado Anschutz Medical Campus, USA Short Talk: MicroRNAs Differentially Expressed in Luminal versus Triple Negative Breast Cancer Control Estrogen Receptor alpha and Growth Factor Receptor Expression and Aspects of Tumor Metabolism
Monday, March 22 \| 8:00AM - 11:00AM Signaling and Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 7 of 7 Mark G. Obukowicz, Pfizer Inc., USA Short Talk: Dissociated Agonist of the Glucocorticoid Receptor (DAGR): 60 Years in the Making (and of Waiting)
Monday, March 22 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Monday, March 22 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Monday, March 22 \| 11:15AM - 1:00PM Poster Setup Room: Shavano/Torreys
Monday, March 22 \| 1:00PM - 10:00PM Poster Viewing Room: Shavano/Torreys
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 1 of 5 Lilach Gilboa, Weizmann Institute of Science, Israel Hormonal Coordination of Niche Formation and Germ Line Stem Cell Establishment
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 2 of 5 Chris R. Gissendanner, University of Louisiana at Monroe, USA The C. elegans NR4A Nuclear Receptor: Conserved Functions in Cell Proliferation and Cell Differentiation during Organ Morphogenesis
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 3 of 5 Wen Xie, University of Pittsburgh, USA Unexpected Hepatotoxicity and Inflammatory Gene Activation in FXR Transgenic Mice
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 4 of 5 Wendong Huang, Beckman Research Institute of City of Hope, USA FXR, Liver Repair and Aging
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Nuclear Receptors in Development and Disease Room: Longs Peak Speaker 5 of 5 * Li Wang, University of Connecticut, USA Nuclear Receptor SHP-dependent Mitochondrial Targeting in Apoptosis Signaling and Tumor Growth
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 6 * Carolyn L. Smith, Baylor College of Medicine, USA
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 6 Michihisa Umetani, University of Houston, USA LXRbeta Promotes Vascular Reendothelialization via a Novel Mechanism Involving non-Nuclear Signaling in Endothelium
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 6 Terry D. Hinds, University of Toledo, USA Discovery of Glucocorticoid Receptor beta in Mice and its Role in Insulin Signaling and Metabolism
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 6 Ronni Nielsen, University of Southern Denmark, Denmark
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 6 Brian Sandri, University of Minnesota, USA Evidence for a Global Role of the Estrogen- Regulated ZEB1 Transcription Factor in Modulating Adiposity through Regulation of FGF-21
Monday, March 22 \| 2:30PM - 4:30PM Workshop 1: Hot Topics: Physiology This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 6 Jens Tiefenbach, University of Toronto, Canada A live Zebrafish-based Screening System for Human Nuclear Receptors Allows for Tissue Selective Drug Discovery
Monday, March 22 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Monday, March 22 \| 5:00PM - 7:00PM Mechanisms of Nuclear Receptor Signaling (Joint) Room: Grays/Longs Peaks Speaker 1 of 5 * Donald P. McDonnell, Duke University School of Medicine, USA
Monday, March 22 \| 5:00PM - 7:00PM Mechanisms of Nuclear Receptor Signaling (Joint) Room: Grays/Longs Peaks Speaker 2 of 5 Christopher K. Glass, University of California, San Diego, USA Lineage-Determining Transcription Factors Prime Cis-regulatory Elements Required for Ligand-dependent Gene Expression
Monday, March 22 \| 5:00PM - 7:00PM Mechanisms of Nuclear Receptor Signaling (Joint) Room: Grays/Longs Peaks Speaker 3 of 5 Keith R. Yamamoto, University of California, San Francisco, USA Cell and Gene Selectivity of Glucocorticoid Action: DNA Sequences as Specific GR Ligands
Monday, March 22 \| 5:00PM - 7:00PM Mechanisms of Nuclear Receptor Signaling (Joint) Room: Grays/Longs Peaks Speaker 4 of 5 Gordon L. Hager, NCI, National Institutes of Health, USA Global Regulation of Chromatin Structure and Gene Expression by Glucocorticoid Receptors
Monday, March 22 \| 5:00PM - 7:00PM Mechanisms of Nuclear Receptor Signaling (Joint) Room: Grays/Longs Peaks Speaker 5 of 5 Jason S. Carroll, Cancer Research UK, University of Cambridge, UK Short Talk: FoxA1 is the Critical Determinant of ER Binding and Activity in Breast Cancer Cells
Monday, March 22 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Shavano/Torreys
Monday, March 22 \| 7:30PM - 10:00PM Poster Session 1 Room: Shavano/Torreys
Tuesday, March 23 \| 7:00AM - 8:00AM Breakfast Room: Shavano/Torreys
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 1 of 7 * Susanne Mandrup, University of Southern Denmark, Denmark
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 2 of 7 Urs Albrecht, University of Fribourg, Switzerland The Clock Component Per2 Coordinates Circadian Output by Interaction with Nuclear Receptors
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 3 of 7 Ueli Schibler, University of Geneva, Switzerland The Regulation of Circadian Gene Expression in Peripheral Cell Types
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 4 of 7 David D. Moore, Baylor College of Medicine, USA Gut Feelings
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 5 of 7 Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland Integrating Metabolic Control by NAD+ Sensors
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 6 of 7 Pavlos Pissios, NGM Bio, USA Short Talk: Regulation of Glucose and Lipid Metabolism by Nicotinamide N-Methyltransferase
Tuesday, March 23 \| 8:00AM - 11:15AM Metabolic Control and Circadian Rhythms Room: Longs Peak Speaker 7 of 7 Thomas P. Burris, Washington University School of Medicine, USA Short Talk: Characterization of Synthetic REV-ERB ligands
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 7 * Kenneth S. Korach, NIEHS, National Institutes of Health, USA
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 7 Donald P. McDonnell, Duke University School of Medicine, USA The ERRalpha/PGC-1 Complex Links HER2/IGF1 Initiated Signaling Events to the Expression of Target Genes that Impact Breast Cancer Pathogenesis
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 7 Michael G. Rosenfeld, University of California, San Diego, USA Epigenetics: Life, Death, and Tumor Translocations
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 7 Carol A. Lange, University of Minnesota, USA Mechanisms of PR Coupling to MAP Kinases
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 7 Geoffrey L. Greene, University of Chicago, USA Structural Basis of ER Ligand Selectivity
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 7 Kendall W. Nettles, The Scripps Research Institute, USA Short Talk: Coupling of Estrogen Receptor Conformation and Ligand Orientation Determine Graded Signaling Activity
Tuesday, March 23 \| 8:00AM - 11:15AM Ligands, Cofactors, and Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 7 of 7 Wei Xu, University of Wisconsin-Madison, USA Short Talk: “Yin-Yang” Principle for Estrogen Receptor Heterodimers in Breast Cancer: A Targeted Molecular Approach for Therapeutic Development
Tuesday, March 23 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Tuesday, March 23 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, March 23 \| 11:15AM - 1:00PM Poster Setup Room: Shavano/Torreys
Tuesday, March 23 \| 1:00PM - 10:00PM Poster Viewing Room: Shavano/Torreys
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Co-Regulators and Post-Transcription al Control Room: Longs Peak Speaker 1 of 6 Inna I. Astapova, Beth Israel Deaconess Medical Center, USA The Nuclear Corepressor, NCoR, Controls the Set Point of the Thyroid Axis In vivo
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Co-Regulators and Post-Transcription al Control Room: Longs Peak Speaker 2 of 6 Karine C. Gauthier, Université de Lyon, France The Thyroid Hormone Receptor TRalpha Protects Against Atherosclerosis Development
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Co-Regulators and Post-Transcription al Control Room: Longs Peak Speaker 3 of 6 Atul Chopra, Case Western Reserve University, USA Hepatic SRC-2 Regulates Energy Balance by Coordinating Bile Secretion and Dietary Fat Absorption
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Co-Regulators and Post-Transcription al Control Room: Longs Peak Speaker 4 of 6 Nan Wu, University of Pennsylvania, USA Arf-bp1 and Pam are Novel Regulators of Circadian Rhythm that Target Rev-erbalpha for Degradation
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Co-Regulators and Post-Transcription al Control Room: Longs Peak Speaker 5 of 6 William Bourguet, Centre de Biochimie Structurale, France A Unique Secondary Structure Switch Controls Constitutive Gene Silencing by Retinoic Acid Receptor
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Co-Regulators and Post-Transcription al Control Room: Longs Peak Speaker 6 of 6 * Patrick R. Griffin, The Scripps Research Institute, USA HDX of Intact VDR/RXR Heterodimer Reveals Agonist and DNA-Induced Conformational Changes Important for Coactivator Interaction
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 7 * Steven K. Nordeen, University of Colorado Health Sciences Center, USA
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 7 Katherine Anne Burns, University of Cincinnati College of Medicine, USA Selective Mutations in the D-domain of Mouse ERalpha Alters Nuclear Translocation and ERalpha’s Non-ERE Gene Regulatory Mechanism
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 7 Nasun Hah, The Salk Institute for Biological Studies, USA Exploring the Direct Estrogen-Regulated Transcriptome in Breast Cancer Cells Using GRO-Seq
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 7 Moray J. Campbell, Roswell Park Cancer Institute, USA VDR Regulation of Histone Modifications and miRNA Combine to Fine-Tune Transcriptional Cycling of Target Genes
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 7 Robert H. Oakley, NIEHS, National Institutes of Health, USA Crosstalk between Glucocorticoid and G Protein-Coupled Receptor Signaling Pathways Mediated by Arrestins
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 7 Joshua D. Stender, University of California, San Diego, USA Control of Pro-Inflammatory Gene Programs by Active Histone Methylation and Demethylation
Tuesday, March 23 \| 2:30PM - 4:30PM Workshop 2: Hot Topics: Gene Regulation This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 7 of 7 Daniel G. Gioeli, University of Virginia, USA CDK9 Regulates AR Activity and Cell Growth through Serine 81 Phosphorylation
Tuesday, March 23 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Tuesday, March 23 \| 5:00PM - 7:00PM Physiology and Metabolism (Joint) Room: Grays/Longs Peaks Speaker 1 of 5 * David J. Mangelsdorf, University of Texas Southwestern Medical Center, USA
Tuesday, March 23 \| 5:00PM - 7:00PM Physiology and Metabolism (Joint) Room: Grays/Longs Peaks Speaker 2 of 5 Bruce M. Spiegelman, Harvard Medical School, USA Transcriptional Regulation of Adipogenesis and Energy Homeostasis
Tuesday, March 23 \| 5:00PM - 7:00PM Physiology and Metabolism (Joint) Room: Grays/Longs Peaks Speaker 3 of 5 Deborah Clegg, Cedars-Sinai Medical Center, USA Estrogen, Adipose Tissue, and The Metabolic Syndrome
Tuesday, March 23 \| 5:00PM - 7:00PM Physiology and Metabolism (Joint) Room: Grays/Longs Peaks Speaker 4 of 5 Ronald M. Evans, HHMI/The Salk Institute, USA PPARs in Metabolism and Disease
Tuesday, March 23 \| 5:00PM - 7:00PM Physiology and Metabolism (Joint) Room: Grays/Longs Peaks Speaker 5 of 5 Austin J. Cooney, Baylor College of Medicine, USA Short Talk: Regulation of ES Cells and iPS by Nuclear Receptors
Tuesday, March 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Shavano/Torreys
Tuesday, March 23 \| 7:30PM - 10:00PM Poster Session 2 Room: Shavano/Torreys
Wednesday, March 24 \| 7:00AM - 8:00AM Breakfast Room: Shavano/Torreys
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 1 of 7 * Joyce J. Repa, University of Texas Southwestern Medical Center, USA
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 2 of 7 Thomas Perlmann, Karolinska Institutet, Ludwig Institute for Cancer Research, Sweden NR4A Orphan Nuclear Receptors Trigger a Neuroprotective Pathway Induced by Elevated Cyclic AMP
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 3 of 7 Gary D. Hammer, University of Michigan, USA SF-1/DAX: Adrenocortical Stem/Progenitor Cell Fate and Multipotency
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 4 of 7 Frances M. Sladek, University of California, Riverside, USA HNF4alpha Function and Regulation -- New Insights into an Old Receptor
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 5 of 7 Erin G. Schuetz, St. Jude Children's Research Hospital, USA Cis and Trans Genetic Variation Affecting Hepatic Nuclear Hormone Receptor Expression
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 6 of 7 Jae W. Lee, Oregon Health and Science University, USA Short Talk: Histone H3-lysine 4 Methyltransferases Specialized for Nuclear Receptor-Mediated Metabolic Homeostasis
Wednesday, March 24 \| 8:00AM - 11:15AM Cell Fate and Tissue Homeostasis Room: Longs Peak Speaker 7 of 7 Kai Ge, NIDDK, National Institutes of Health, USA Short Talk: Epigenetic Regulation of PPARgamma and Adipogenesis
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 7 * Dean P. Edwards, Baylor College of Medicine, USA
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 7 Roland Schüle, Universitaetsklinikum Freiburg, Germany Androgen Receptor Function is Regulated by Histone Demethylases: Implication for Prostate Cancer
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 7 W. Lee Kraus, University of Texas Southwestern Medical Center, USA Genomic Analyses of Estrogen-Regulated Transcription Reveal New Facets of the Estrogen Signaling Pathway
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 7 Raphael Metivier, Université de Rennes I, France Estrogen Receptor Transcriptional Activity: A Dynamic Integration of Multi-Leveled Information
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 7 Shigeaki Kato, University of Tokyo, Japan Epigenetic Regulators Supporting Nuclear Receptor Function
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 7 Inez Rogatsky, Weill Medical College of Cornell University, USA Short Talk: The Role of GRIP1 in Type I Interferon Signaling and Glucocorticoid-Induced Immunosuppression
Wednesday, March 24 \| 8:00AM - 11:15AM Chromatin and Transcription This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 7 of 7 Catharine L. Smith, University of Arizona, USA Short Talk: Histone Deacetylases Function as Glucocorticoid Receptor Coactivators
Wednesday, March 24 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Wednesday, March 24 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Wednesday, March 24 \| 11:15AM - 1:00PM Poster Setup Room: Shavano/Torreys
Wednesday, March 24 \| 1:00PM - 10:00PM Poster Viewing Room: Shavano/Torreys
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Nuclear Receptors in Metabolism Room: Longs Peak Speaker 1 of 6 * Carolyn L. Cummins, University of Toronto, Canada
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Nuclear Receptors in Metabolism Room: Longs Peak Speaker 2 of 6 Kari T. Chambers, Washington University School of Medicine, USA PGC-1beta Regulates Hepatic Energy Metabolism Under ad Libitum Fed Conditions
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Nuclear Receptors in Metabolism Room: Longs Peak Speaker 3 of 6 Philipp M. Kulozik, German Cancer Research Center, Germany Lack of Hepatic TBL1/TBLR1 Transcriptional Co-Activator Function Promotes Obesity-Related Dyslipidemia
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Nuclear Receptors in Metabolism Room: Longs Peak Speaker 4 of 6 Hong Soon Kang, NIEHS, National Institutes of Health, USA Retinoid-Related Orphan Receptor alpha (RORalpha) Positively Regulates Obesity, Hepatic Steatosis, and Inflammation
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Nuclear Receptors in Metabolism Room: Longs Peak Speaker 5 of 6 Yanqiao Zhang, Northeastern Ohio Universities College of Medicine, USA Identification of Novel Pathways that Control FXR-mediated Hypocholesterolemia
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Nuclear Receptors in Metabolism Room: Longs Peak Speaker 6 of 6 Katja A. Lamia, The Scripps Research Institute, USA AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 7 * † Jonna Frasor, University of Illinois, Chicago, USA
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 7 Shannon T. Bailey, WuXi NextCODE, USA Loss of ER-Regulated microRNAs is Fundamental to Hormone-Independent Breast Cancer Cells
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 7 Ruby Dhar, University of Chicago, USA Genome Wide RNAi Screen to Identify Novel Targets for Estrogen Signaling in Breast Cancer
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 7 Zeynep Madak-Erdogan, University of Illinois at Urbana-Champaign, USA Critical Role of ERK2 in Estrogen Receptor alpha (ERalpha)-mediated Regulation of Gene Expression and Proliferation of Breast Cancer Cells
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 7 Lillian J. Eichner, The Salk Institute, USA miR-378 Induces Metabolic Shift in Breast Cancer Cells via the ERRgamma Transcriptional Pathway
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 7 Jun Qin, Baylor College of Medicine, USA COUP-TFII Regulates Angiogenesis to Promote Tumor Growth and Metastasis
Wednesday, March 24 \| 2:30PM - 4:30PM Workshop 3: Hot Topics: Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 7 of 7 Matthew J. Schiewer, Thomas Jefferson University, USA Impact of PARP1 on AR Signaling and Therapeutic Response in Prostate Cancer
Wednesday, March 24 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Wednesday, March 24 \| 5:00PM - 7:15PM Coregulators and Gene Expression (Joint) Room: Grays/Longs Peaks Speaker 1 of 6 * Carole R. Mendelson, University of Texas Southwestern Medical Center, USA
Wednesday, March 24 \| 5:00PM - 7:15PM Coregulators and Gene Expression (Joint) Room: Grays/Longs Peaks Speaker 2 of 6 Bert W. O'Malley, Baylor College of Medicine, USA NR Coactivators: Physiology and Disease
Wednesday, March 24 \| 5:00PM - 7:15PM Coregulators and Gene Expression (Joint) Room: Grays/Longs Peaks Speaker 3 of 6 Catherine C. Thompson, Pfizer, USA LXR is a Therapeutic Target for Skin Aging and Dermal Inflammatory Indications
Wednesday, March 24 \| 5:00PM - 7:15PM Coregulators and Gene Expression (Joint) Room: Grays/Longs Peaks Speaker 4 of 6 Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA Epigenetic Regulation of Nuclear Receptor Expression, Cistromes, and Function
Wednesday, March 24 \| 5:00PM - 7:15PM Coregulators and Gene Expression (Joint) Room: Grays/Longs Peaks Speaker 5 of 6 Ralf Kittler, University of Texas Southwestern Medical Center, USA Short Talk: A cis-Regulatory Map for Nuclear Receptors in Breast Cancer
Wednesday, March 24 \| 5:00PM - 7:15PM Coregulators and Gene Expression (Joint) Room: Grays/Longs Peaks Speaker 6 of 6 Ronald N. Margolis, NIDDK, National Institutes of Health, USA Short Talk: dkCOIN: A BIG Solution to Data Integration
Wednesday, March 24 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Shavano/Torreys
Wednesday, March 24 \| 7:30PM - 10:00PM Poster Session 3 Room: Shavano/Torreys
Thursday, March 25 \| 7:00AM - 8:00AM Breakfast Room: Shavano/Torreys
Thursday, March 25 \| 8:00AM - 11:15AM Nuclear Receptors in Metabolism Room: Longs Peak Speaker 1 of 6 Joyce J. Repa, University of Texas Southwestern Medical Center, USA Nuclear Receptors in Pancreatic Beta Cells
Thursday, March 25 \| 8:00AM - 11:15AM Nuclear Receptors in Metabolism Room: Longs Peak Speaker 2 of 6 Steven A. Kliewer, University of Texas Southwestern Medical Center, USA Regulation of Metabolism by Nuclear Receptor-FGF Pathways
Thursday, March 25 \| 8:00AM - 11:15AM Nuclear Receptors in Metabolism Room: Longs Peak Speaker 3 of 6 Anastasia Kralli, Johns Hopkins Medical School, USA ERR Function in Energy Metabolism and Cancer
Thursday, March 25 \| 8:00AM - 11:15AM Nuclear Receptors in Metabolism Room: Longs Peak Speaker 4 of 6 * Vincent Giguère, McGill University, Canada Metabolic Gene Networks in Normal and Cancer Cells: One Nuclear Receptor Subfamily to Rule them All
Thursday, March 25 \| 8:00AM - 11:15AM Nuclear Receptors in Metabolism Room: Longs Peak Speaker 5 of 6 Carolyn L. Cummins, University of Toronto, Canada Short Talk: LXRbeta is Required for Glucocorticoid-Induced Hyperglycemia and Hepatosteatosis
Thursday, March 25 \| 8:00AM - 11:15AM Nuclear Receptors in Metabolism Room: Longs Peak Speaker 6 of 6 Yihong Wan, University of Texas Southwestern Medical Center, USA Short Talk: PGC1beta Mediates PPARgamma Activation of Osteoclastogenesis and Rosiglitazone-Induced Bone Loss
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 1 of 7 * John A. Cidlowski, NIEHS, National Institutes of Health, USA
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 2 of 7 Kathryn B. Horwitz, University of Colorado Health Sciences Center, USA Women’s Hormones, Breast Cancer Metastasis and Cancer Stem Cells
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 3 of 7 Jan-Åke Gustafsson, University of Houston, USA Novel Biological Roles of LXRs
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 4 of 7 Karen E. Knudsen, Thomas Jefferson University, Kimmel Cancer Center, USA New Paradigms in Tumor Suppression: The RB-E2F Axis and Nuclear Receptor Regulation in Cancer
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 5 of 7 Charles L. Sawyers, Memorial Sloan-Kettering Cancer Center, USA Overcoming Resistance to Anti-Androgen Therapy in Prostate Cancer
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 6 of 7 Yun Qiu, University of Maryland School of Medicine, USA Short Talk: Androgen Receptor Splicing Variants and Castration Resistance in Prostate Cancer
Thursday, March 25 \| 8:00AM - 11:15AM Steroid Receptors, Signaling and Cancer This session is from Nuclear Receptors: Signaling Room: Grays Peak Speaker 7 of 7 Suzanne D. Conzen, University of Chicago, USA Short Talk: Identification of a Glucocorticoid Receptor Signature in Primary Human Breast Cancers
Thursday, March 25 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Thursday, March 25 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Thursday, March 25 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Thursday, March 25 \| 5:00PM - 7:00PM Nuclear Receptors, Signaling, and Gene Regulation (Joint) Room: Grays/Longs Peaks Speaker 1 of 5 * Ronald M. Evans, HHMI/The Salk Institute, USA
Thursday, March 25 \| 5:00PM - 7:00PM Nuclear Receptors, Signaling, and Gene Regulation (Joint) Room: Grays/Longs Peaks Speaker 2 of 5 David J. Mangelsdorf, University of Texas Southwestern Medical Center, USA Nutrient-Sensing and Metabolic Control by Nuclear Receptors
Thursday, March 25 \| 5:00PM - 7:00PM Nuclear Receptors, Signaling, and Gene Regulation (Joint) Room: Grays/Longs Peaks Speaker 3 of 5 Benita S. Katzenellenbogen, University of Illinois, USA Genomics of Estrogen Receptor Signaling in Breast Cancer and Endocrine Resistance
Thursday, March 25 \| 5:00PM - 7:00PM Nuclear Receptors, Signaling, and Gene Regulation (Joint) Room: Grays/Longs Peaks Speaker 4 of 5 Myles Brown, Dana-Farber Cancer Institute, USA Nuclear Receptor Cistromes and Epigenomes
Thursday, March 25 \| 5:00PM - 7:00PM Nuclear Receptors, Signaling, and Gene Regulation (Joint) Room: Grays/Longs Peaks Speaker 5 of 5 Edwin Cheung, University of Macau, Macau Short Talk: Global and Funcational Analyses of ER-Mediated Long-Range Chromatin Interactions
Thursday, March 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Shavano/Torreys
Thursday, March 25 \| 8:00PM - 11:00PM Entertainment Room: Shavano/Torreys
Thursday, March 25 \| 8:00PM - 11:00PM Cash Bar Room: Shavano/Torreys
Friday, March 26 \| 10:22AM - 10:22AM Departure *Session Chair †Invited, not yet responded.