Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
	Diabetes: Glucose Control and Beyond (2020J5)
Diabetes (2017J3)
Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies (2016T2)
Diabetes and Metabolic Dysfunction (2015J6)
Challenges and Opportunities in Diabetes Research and Treatment (2014J1)
Diabetes - New Insights into Mechanism of Disease and its Treatment (2013J6)
Pathogenesis of Diabetes: Emerging Insights into Molecular Mechanisms (2012J8)
Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction (2011J1)

Web Desc
Diabetes joint with Islet Biology Organizer(s): Juleen R. Zierath, Philippe Froguel, Nancy A. Thornberry and Michael P. Czech Date: April 12 - 17, 2010 Location: Whistler Conference Centre, Whistler, BC, Canada Sponsored by Eli Lilly and Company and Hoffmann-La Roche, Inc. Summary of Meeting: The increased incidence of Type 2 diabetes mellitus is a growing threat to global health. This chronic and progressive metabolic disease is characterized by insulin resistance and beta cell defects, arising from environmental and genetic factors. Multi-disciplinary approaches that capitalize on genetic, genomic and physiological disciplines are required to gain insight into Type 2 diabetes pathogenesis through an increased understanding of the complicated biology that contributes to the development of insulin resistance and beta cell failure. The meeting will focus on latest advancements in our understanding of the molecular pathogenesis of Type 2 diabetes to accelerate the translation of experimental and clinical discoveries to link phenotype to genotype. Particular emphasis will be placed on 1) epigenetics, genetics and pharmacogenomics of metabolic responses, 2) links between pathways linking obesity, inflammation, and insulin resistance and 3) Type 2 diabetes in children and adolescents. A key goal for the meeting will be to facilitate collaborative interactions between basic and clinical scientists focused on prediction, prevention, and treatment of insulin resistance and diabetes. Scholarship Deadline: December 14 2009 Discounted Abstract Deadline: December 14 2009 Abstract Deadline: January 15 2010 Discounted Registration Deadline: February 12 2010 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Merck & Co., Inc. Merck Research Laboratories We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 1R13DK084688-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Diabetes

joint with Islet Biology

Organizer(s): Juleen R. Zierath, Philippe Froguel, Nancy A. Thornberry and Michael P. Czech

Date: April 12 - 17, 2010
Location: Whistler Conference Centre, Whistler, BC, Canada

Sponsored by Eli Lilly and Company and Hoffmann-La Roche, Inc.

Summary of Meeting:

The increased incidence of Type 2 diabetes mellitus is a growing threat to global health. This chronic and progressive metabolic disease is characterized by insulin resistance and beta cell defects, arising from environmental and genetic factors. Multi-disciplinary approaches that capitalize on genetic, genomic and physiological disciplines are required to gain insight into Type 2 diabetes pathogenesis through an increased understanding of the complicated biology that contributes to the development of insulin resistance and beta cell failure. The meeting will focus on latest advancements in our understanding of the molecular pathogenesis of Type 2 diabetes to accelerate the translation of experimental and clinical discoveries to link phenotype to genotype. Particular emphasis will be placed on 1) epigenetics, genetics and pharmacogenomics of metabolic responses, 2) links between pathways linking obesity, inflammation, and insulin resistance and 3) Type 2 diabetes in children and adolescents. A key goal for the meeting will be to facilitate collaborative interactions between basic and clinical scientists focused on prediction, prevention, and treatment of insulin resistance and diabetes.

Scholarship Deadline: December 14 2009

Discounted Abstract Deadline: December 14 2009

Abstract Deadline: January 15 2010

Discounted Registration Deadline: February 12 2010

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Merck & Co., Inc.

Merck Research Laboratories

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK084688-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Monday, April 12 \| 3:00PM - 7:30PM Registration Room: Foyer
Monday, April 12 \| 6:30PM - 7:30PM Refreshments Room: Foyer
Monday, April 12 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sea to Sky Ballroom B,C Speaker 1 of 4 * Juleen R. Zierath, Karolinska Institutet, Sweden
Monday, April 12 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sea to Sky Ballroom B,C Speaker 2 of 4 Victor R. Ambros, University of Massachusetts, USA MicroRNAs in Model Systems and Human Disease
Monday, April 12 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sea to Sky Ballroom B,C Speaker 3 of 4 * Markus Stoffel, ETH Zürich, Switzerland
Monday, April 12 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Sea to Sky Ballroom B,C Speaker 4 of 4 Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA Mitochondrial Role in Cell Cycle Control and Autophagy
Tuesday, April 13 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky Ballroom A, Lower Level
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 1 of 7 * Simeon Taylor, University of Maryland School of Medicine, USA
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 2 of 7 Philippe Froguel, Imperial College of London, UK Genome Structure and Point DNA Variation: The Power of the Extreme in Diabesity
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 3 of 7 Mark I. McCarthy, University of Oxford, UK Type 2 Diabetes: Susceptibility Variants across the Allele Frequency Spectrum
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 4 of 7 Jose C. Florez, Massachusetts General Hospital, USA Genetic Epidemiology of Type 2 Diabetes and Related Traits in General Populations
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 5 of 7 Eric Schadt, Mount Sinai School of Medicine, USA Multi-Tissue Networks Elucidate Type 2 Diabetes Circuits
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 6 of 7 Jussi A. Pihlajamäki, Kuopio University Hospital, Finland Short Talk: Alternative Splicing is Regulated by Weight Loss and Differs between Fat Depots in Humans
Tuesday, April 13 \| 8:00AM - 11:15AM Genetics of Diabetes Room: Sea to Sky Ballroom C Speaker 7 of 7 Jeremy B.M. Jowett, Baker IDI Heart and Diabetes Institute, Australia Short Talk: Expression Profiling Identifies Biomarkers for Progression to Type 2 Diabetes
Tuesday, April 13 \| 8:00AM - 11:00AM From Stem Cell Development to Transplantation This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 1 of 6 * Catherine Lee May, University of Pennsylvania, USA
Tuesday, April 13 \| 8:00AM - 11:00AM From Stem Cell Development to Transplantation This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 2 of 6 Bernhard J. Hering, University of Minnesota, USA Islet Transplantation: Today and Tomorrow
Tuesday, April 13 \| 8:00AM - 11:00AM From Stem Cell Development to Transplantation This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 3 of 6 Anne Grapin-Botton, University of Copenhagen, Denmark Role of Pancreas 3D Architecture in Endocrine Cell Development
Tuesday, April 13 \| 8:00AM - 11:00AM From Stem Cell Development to Transplantation This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 4 of 6 Lori Sussel, University of Colorado Anschutz Medical Campus, USA Regulation of Pancreatic Islet Cell Fates
Tuesday, April 13 \| 8:00AM - 11:00AM From Stem Cell Development to Transplantation This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 5 of 6 Maike Sander, University of California, San Diego, USA Control of Cell Fate Choice in the Pancreas
Tuesday, April 13 \| 8:00AM - 11:00AM From Stem Cell Development to Transplantation This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 6 of 6 Dina Fomina-Yadlin, Harvard University, USA Short Talk: Altering Pancreatic Cell State with Small Molecules
Tuesday, April 13 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Tuesday, April 13 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, April 13 \| 11:15AM - 1:00PM Poster Setup Room: Foyer/Mountain View/Sea to Sky Ballroom A
Tuesday, April 13 \| 1:00PM - 10:00PM Poster Viewing Room: Foyer/Mountain View/Sea to Sky Ballroom A
Tuesday, April 13 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Tuesday, April 13 \| 5:00PM - 7:00PM Cell and Tissue Signaling Mechanisms in Diabetes Room: Sea to Sky Ballroom C Speaker 1 of 5 * Adria Giacca, University of Toronto, Canada
Tuesday, April 13 \| 5:00PM - 7:00PM Cell and Tissue Signaling Mechanisms in Diabetes Room: Sea to Sky Ballroom C Speaker 2 of 5 Claire C. Bastie, Albert Einstein College of Medicine, USA Fyn Kinase and LKB1: A Novel Pathway Regulating Lipid Utilization and Energy Expenditure
Tuesday, April 13 \| 5:00PM - 7:00PM Cell and Tissue Signaling Mechanisms in Diabetes Room: Sea to Sky Ballroom C Speaker 3 of 5 Robert E. Lewis, University of Nebraska Medical Center, USA Molecular Scaffolds as Energy Sensors
Tuesday, April 13 \| 5:00PM - 7:00PM Cell and Tissue Signaling Mechanisms in Diabetes Room: Sea to Sky Ballroom C Speaker 4 of 5 Bei B. Zhang, Pfizer Inc., USA Modulation of Glucose, Amino Acid and Lipid Metabolism Pathways with Pharmacological Agents
Tuesday, April 13 \| 5:00PM - 7:00PM Cell and Tissue Signaling Mechanisms in Diabetes Room: Sea to Sky Ballroom C Speaker 5 of 5 Philipp Gut, Nestlé Institute of Health Sciences, Switzerland Short Talk: In vivo Drug Discovery of New Regulators of Glucose Metabolism using Transgenic “Gluconeogenesis Reporter” Zebrafish
Tuesday, April 13 \| 5:00PM - 7:00PM Signaling in Pancreatic B-Cells This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 1 of 5 * Rohit N. Kulkarni, Joslin Diabetes Center, Harvard Medical School, USA
Tuesday, April 13 \| 5:00PM - 7:00PM Signaling in Pancreatic B-Cells This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 2 of 5 Eckhard Lammert, Heinrich-Heine-University / German Diabetes Center, Germany Role of Blood Vessels in Pancreatic Islet Development and Function
Tuesday, April 13 \| 5:00PM - 7:00PM Signaling in Pancreatic B-Cells This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 3 of 5 Marc Prentki, Montreal Diabetes Research Center, Canada Beta Cell Metabolic Signaling and Dysfunction in Type 2 Diabetes
Tuesday, April 13 \| 5:00PM - 7:00PM Signaling in Pancreatic B-Cells This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 4 of 5 Ingo B. Leibiger, Karolinska Institutet, Sweden Insulin Signaling in the Pancreatic Beta Cell
Tuesday, April 13 \| 5:00PM - 7:00PM Signaling in Pancreatic B-Cells This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 5 of 5 Jocelyn E. Manning Fox, University of Alberta, Canada Short Talk: Small Ubiquitin-Like Modifier 1 (SUMO1) Directly and Acutely Regulates Insulin Exocytosis from Human beta-Cells
Tuesday, April 13 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Foyer/Mountain View/Sea to Sky Ballroom A
Tuesday, April 13 \| 7:30PM - 10:00PM Poster Session 1 Room: Foyer/Mountain View/Sea to Sky Ballroom A
Wednesday, April 14 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky Ballroom A, Lower Level
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 1 of 7 * Jeffrey S. Elmendorf, Indiana University School of Medicine, USA
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 2 of 7 Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA A Novel Pathway in Adipose Tissue and Liver that Regulates Adiposity
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 3 of 7 Kenneth Walsh, University of Virginia School of Medicine, USA Discovery of Novel Myokines
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 4 of 7 Philipp E. Scherer, University of Texas Southwestern Medical Center, USA Discovery of Novel Adipokines
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 5 of 7 Fatima Bosch, Universitat Autonoma Barcelona, Spain Gene Therapy and Diabetes
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 6 of 7 Tsu-Shuen Tsao, University of Arizona, USA Short Talk: Inhibition of Adiponectin Oligomerization under Oxidizing Conditions and Induction of an Oxidizing Redox Environment in Endoplasmic Reticulum of 3T3-L1 Adipocytes Exposed to High Concentrations of Palmitate
Wednesday, April 14 \| 8:00AM - 11:15AM Intertissue Communication Room: Sea to Sky Ballroom C Speaker 7 of 7 Marianna Sadagurski, Wayne State University, USA Short Talk: Inactivation of Foxo1 in Leptin Receptor (LepRb)-Expressing Neurons Reverses Obesity and Diabetes, Caused by Deletion of Insulin Receptor Substrate 2 (Irs2)
Wednesday, April 14 \| 8:00AM - 11:00AM Transcriptional Networks Signaling This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 1 of 6 * Maike Sander, University of California, San Diego, USA
Wednesday, April 14 \| 8:00AM - 11:00AM Transcriptional Networks Signaling This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 2 of 6 Catherine Lee May, University of Pennsylvania, USA Islet-1 and its Cofactor Ldb1 in the Endocrine Pancreas
Wednesday, April 14 \| 8:00AM - 11:00AM Transcriptional Networks Signaling This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 3 of 6 Markus Stoffel, ETH Zürich, Switzerland MicroRNA Networks
Wednesday, April 14 \| 8:00AM - 11:00AM Transcriptional Networks Signaling This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 4 of 6 Roland W. Stein, Vanderbilt University Medical Center, USA
Wednesday, April 14 \| 8:00AM - 11:00AM Transcriptional Networks Signaling This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 5 of 6 Alan D. Attie, University of Wisconsin-Madison, USA Networks of QTLs, mRNAs, and microRNAs in Beta Cell Growth and Function
Wednesday, April 14 \| 8:00AM - 11:00AM Transcriptional Networks Signaling This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 6 of 6 Melissa K. Thomas, Massachusetts General Hospital, USA Short Talk: TCF7L2 Deficiency Alters Mouse Metabolic and Islet Cell Functions with Aging
Wednesday, April 14 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Wednesday, April 14 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Wednesday, April 14 \| 11:15AM - 1:00PM Poster Setup Room: Foyer/Mountain View/Sea to Sky Ballroom A
Wednesday, April 14 \| 1:00PM - 10:00PM Poster Viewing Room: Foyer/Mountain View/Sea to Sky Ballroom A
Wednesday, April 14 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Wednesday, April 14 \| 5:00PM - 7:15PM Molecular Mechanisms in Insulin Secretion and Action (Joint) Room: Sea to Sky Ballroom B,C Speaker 1 of 6 * Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Wednesday, April 14 \| 5:00PM - 7:15PM Molecular Mechanisms in Insulin Secretion and Action (Joint) Room: Sea to Sky Ballroom B,C Speaker 2 of 6 C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA Insulin Signaling and Insulin Resistance: The Ultimate Systems Biology Problem
Wednesday, April 14 \| 5:00PM - 7:15PM Molecular Mechanisms in Insulin Secretion and Action (Joint) Room: Sea to Sky Ballroom B,C Speaker 3 of 6 Per-Olof Berggren, Karolinska Institutet, Sweden Systems Biology Approach to Study Beta Cell Function and Survival
Wednesday, April 14 \| 5:00PM - 7:15PM Molecular Mechanisms in Insulin Secretion and Action (Joint) Room: Sea to Sky Ballroom B,C Speaker 4 of 6 Morris J. Birnbaum, Pfizer Inc., USA The Role of Akt in the Regulation of Hepatic Metabolism by Insulin
Wednesday, April 14 \| 5:00PM - 7:15PM Molecular Mechanisms in Insulin Secretion and Action (Joint) Room: Sea to Sky Ballroom B,C Speaker 5 of 6 Weiping Han, Singapore Bioimaging Consortium, Singapore Short Talk: Molecular Regulation of Calcium-Dependent Insulin Secretion
Wednesday, April 14 \| 5:00PM - 7:15PM Molecular Mechanisms in Insulin Secretion and Action (Joint) Room: Sea to Sky Ballroom B,C Speaker 6 of 6 Jennifer L. Estall, Institut de Recherches Cliniques de Montréal, Canada Short Talk: PGC-1alpha Negatively Regulates Hepatic FGF21 Expression by Modulating the Heme/Rev-Erbalpha Axis
Wednesday, April 14 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Foyer/Mountain View/Sea to Sky Ballroom A
Wednesday, April 14 \| 7:30PM - 10:00PM Poster Session 2 Room: Foyer/Mountain View/Sea to Sky Ballroom A
Thursday, April 15 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky Ballroom A, Lower Level
Thursday, April 15 \| 7:00AM - 11:00AM Poster Setup Room: Foyer/Mountain View/Sea to Sky Ballroom A
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 1 of 7 * Nancy A. Thornberry, Kallyope, Inc., USA
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 2 of 7 Diane Mathis, Harvard Medical School, USA Lymphocyte Regulation of Adipose Tissue Inflammation
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 3 of 7 Roger J. Davis, HHMI/University of Massachusetts Medical School, USA Pathogenesis Mechanisms of the JNK Pathway
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 4 of 7 Rémy G. Burcelin, Institute of Molecular Medicine, France Intestinal Microflora, Inflammation, and Metabolic Diseases
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 5 of 7 Michael P. Czech, University of Massachusetts Medical School, USA RNAi-Based Strategies to Address Metabolic Dysfunction
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 6 of 7 Birgitte Lindegaard, Rigshospitalet, Denmark Short Talk: IL-18 Increases Intramuscular Fat Oxidation by Activating AMPK
Thursday, April 15 \| 8:00AM - 11:15AM Inflammatory Mechanisms and Insulin Resistance Room: Sea to Sky Ballroom C Speaker 7 of 7 Heather C. Denroche, University of British Columbia, Canada Short Talk: Leptin Therapy Reverses Fasting Hyperglycemia and Enhances Insulin Sensitivity in Diabetic Mice, Independent of Hepatic Leptin Signaling
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 1 of 7 * Per-Olof Berggren, Karolinska Institutet, Sweden
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 2 of 7 Patrik Rorsman, Oxford Centre for Diabetes, Endocrinology and Metabolism, UK Calcium Channels and Insulin Exocytosis
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 3 of 7 Michele Solimena, Dresden University of Technology, Germany Signaling from the Insulin Granule to the Nucleus
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 4 of 7 Gerard Karsenty, Columbia University Medical Center, USA Regulation of Glucose Homeostasis by Osteocalcin
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 5 of 7 Herbert Y. Gaisano, University of Toronto, Canada Molecular Mechanism of Insulin Granule-Granule Fusion Contributing to Biphasic Insulin Secretion
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 6 of 7 Ja Young Kim-Muller, Pfizer Inc, USA Short Talk: Abnormal Regulation of Basal Insulin Secretion in Mice Homozygous for a Constitutively Deacetylated FoxO1 Allele
Thursday, April 15 \| 8:00AM - 11:15AM Control of Insulin Secretory Machinery in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 7 of 7 Hail Kim, Korea Advanced Institute of Science and Technology, South Korea Short Talk: Serotonin Regulates Pancreatic beta-Cell Mass during Pregnancy
Thursday, April 15 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Thursday, April 15 \| 11:00AM - 5:00PM Poster Viewing Room: Foyer/Mountain View/Sea to Sky Ballroom A
Thursday, April 15 \| 11:30AM - 12:30PM Lunch Room: Foyer/Mountain View/Sea to Sky Ballroom A
Thursday, April 15 \| 12:30PM - 2:30PM Poster Session 3 Room: Foyer/Mountain View/Sea to Sky Ballroom A
Thursday, April 15 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Thursday, April 15 \| 5:00PM - 7:15PM Emerging Targets for Improving Insulin Action and Secretion (Joint) Room: Sea to Sky Ballroom B,C Speaker 1 of 6 * C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Thursday, April 15 \| 5:00PM - 7:15PM Emerging Targets for Improving Insulin Action and Secretion (Joint) Room: Sea to Sky Ballroom B,C Speaker 2 of 6 Richard D. DiMarchi, Indiana University and Novo Nordisk, USA Novel Glucagon-Like Chimera Peptides – Virtues of Combinatorial Pharmacology
Thursday, April 15 \| 5:00PM - 7:15PM Emerging Targets for Improving Insulin Action and Secretion (Joint) Room: Sea to Sky Ballroom B,C Speaker 3 of 6 David E. Moller, Eli Lilly and Company, USA Challenges and Opportunities for Diabetes Drug Discovery
Thursday, April 15 \| 5:00PM - 7:15PM Emerging Targets for Improving Insulin Action and Secretion (Joint) Room: Sea to Sky Ballroom B,C Speaker 4 of 6 Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland Integrating Metabolic Control by NAD+ Sensors
Thursday, April 15 \| 5:00PM - 7:15PM Emerging Targets for Improving Insulin Action and Secretion (Joint) Room: Sea to Sky Ballroom B,C Speaker 5 of 6 Tian-Qiang Sun, Rigel Pharmaceuticals, Inc., USA Short Talk: Small Molecule Adiponectin Mimetics Improve Hepatic Steatosis and Insulin Sensitivity in Diabetic Mouse Models
Thursday, April 15 \| 5:00PM - 7:15PM Emerging Targets for Improving Insulin Action and Secretion (Joint) Room: Sea to Sky Ballroom B,C Speaker 6 of 6 Christine Esau, Arcturus Therapeutics, USA Short Talk: Inhibition of Let-7 with Anti-miR Oligonucleotides Improves Insulin Resistance in DIO Mice
Thursday, April 15 \| 7:15PM - 7:15PM On Own for Dinner
Friday, April 16 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky Ballroom A, Lower Level
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 1 of 7 * Michael P. Czech, University of Massachusetts Medical School, USA
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 2 of 7 Andrew Hattersley, University of Exeter Medical School, UK Learning from Genetic Beta Cell Defects in Man
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 3 of 7 Anna Moore, Michigan State University, USA Imaging Pancreatic Islets in vivo: Current Status
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 4 of 7 Juleen R. Zierath, Karolinska Institutet, Sweden Gene/Environment Influence on Skeletal Muscle Insulin Sensitivity in Type 2 Diabetic Patients
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 5 of 7 Peter Arner, Karolinska Institutet, Sweden Dysfunction in Human Adipose Tissue and Insulin Resistance
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 6 of 7 Michael Ristow, Swiss Federal Institute of Technology Zurich - ETH, Switzerland Short Talk: Impaired Insulin Signaling Extends Life Span by Increasing Oxidative Stress
Friday, April 16 \| 8:00AM - 11:15AM Insulin Secretion and Action in Humans (Joint) Room: Sea to Sky Ballroom B,C Speaker 7 of 7 Mary Armanios, Johns Hopkins University School of Medicine, USA Short Talk: Short Telomeres Lead to beta-cell Dysfunction and Impair Glucose Tolerance
Friday, April 16 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Friday, April 16 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Friday, April 16 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Friday, April 16 \| 5:00PM - 7:00PM Type 2 Diabetes in Children and Adolescents Room: Sea to Sky Ballroom C Speaker 1 of 5 * Philippe Froguel, Imperial College of London, UK
Friday, April 16 \| 5:00PM - 7:00PM Type 2 Diabetes in Children and Adolescents Room: Sea to Sky Ballroom C Speaker 2 of 5 Rebecca Anne Simmons, University of Pennsylvania School of Medicine, USA Epigenetic Mechanisms in the Development of Type 2 Diabetes
Friday, April 16 \| 5:00PM - 7:00PM Type 2 Diabetes in Children and Adolescents Room: Sea to Sky Ballroom C Speaker 3 of 5 Susan Ozanne, University of Cambridge, UK Early Life Programming of Type 2 Diabetes
Friday, April 16 \| 5:00PM - 7:00PM Type 2 Diabetes in Children and Adolescents Room: Sea to Sky Ballroom C Speaker 4 of 5 Phil Zeitler, University of Colorado, Denver, USA Type 2 Diabetes in Children and Adolescents: Epidemiology, Pathophysiology, and Comorbidities
Friday, April 16 \| 5:00PM - 7:00PM Type 2 Diabetes in Children and Adolescents Room: Sea to Sky Ballroom C Speaker 5 of 5 Kasper Rud, University of Copenhagen, Denmark Short Talk: Effects of Gestational Low Protein Diet Followed by Postnatal High Fat or High Sucrose Diet on the Interplay between Fat and Carbohydrate Metabolism in Rat Mitochondria
Friday, April 16 \| 5:00PM - 7:00PM Beta Cell Stress in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 1 of 5 * Marc Prentki, Montreal Diabetes Research Center, Canada
Friday, April 16 \| 5:00PM - 7:00PM Beta Cell Stress in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 2 of 5 Marc Y. Donath, University Hospital Basel, Switzerland Islet Inflammation in Type 2 Diabetes: Novel Mechanisms and Treatment
Friday, April 16 \| 5:00PM - 7:00PM Beta Cell Stress in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 3 of 5 Thomas Mandrup-Poulsen, Hagedorn Research Institute, Denmark Cytokine Signaling in Inflammatory beta-Cell Destruction
Friday, April 16 \| 5:00PM - 7:00PM Beta Cell Stress in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 4 of 5 Rohit N. Kulkarni, Joslin Diabetes Center, Harvard Medical School, USA Insulin/IGF-I Signaling, Mitochondrial Function and Endoplasmic Stress in Pancreatic beta-Cells
Friday, April 16 \| 5:00PM - 7:00PM Beta Cell Stress in Diabetes This session is from Islet Biology Room: Sea to Sky Ballroom B Speaker 5 of 5 Raghavendra G. Mirmira, Indiana University School of Medicine, USA Short Talk: The Unique Hypusine Modification of eIF5A Promotes Islet Inflammation and Dysfunction during the Development of Diabetes
Friday, April 16 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Foyer/Mountain View/Sea to Sky Ballroom A
Friday, April 16 \| 8:00PM - 11:00PM Entertainment Room: Foyer/Mountain View/Sea to Sky Ballroom A
Friday, April 16 \| 8:00PM - 11:00PM Cash Bar Room: Foyer/Mountain View/Sea to Sky Ballroom A
Saturday, April 17 \| 10:25AM - 10:25AM Departure *Session Chair.