Web Desc
TGF-beta in Immune Responses: From Bench to Bedside
Organizer(s): Wanjun Chen, Howard L. Weiner and Richard A. Flavell
Date: January 07 - 12, 2011
Location: Snowbird Resort, Snowbird, UT, USA
Sponsored by Genzyme Corporation and ImClone Systems Corporation
For important information on the coronavirus, please click here
Summary of Meeting:
The recent discovery of TGF-beta as a key regulator in immune responses (particularly in regulatory T cell and Th17 cell differentiation) has put TGF-beta at the center stage of immunology, a position it deserves. Despite great progress in the field, key questions related to TGF-beta re-programming T cells are largely unknown. In this regard, it is imperative to understand the molecular mechanisms by which TGF-beta controls such diverse T cell programming. Elucidation of these pathways would allow us to apply the knowledge and information acquired from basic studies to understand the pathogenesis of human immune-associated diseases and develop therapeutic practices in experimental and ultimately clinical settings. In addition, roles for TGF-beta in innate immunity, the mucosal immune system, autoimmunity and inflammation, anti-tumor immunity, and HIV-mediated immune deficiency have been gradually disclosed and appreciated. Thus, it is necessary to gather experts in the field together to discuss new findings and update the pivotal role of TGF-beta in the immune system, with the aim to lay out the critical and key questions and point out possible directions. The Keystone Symposium is the ideal platform to reach this goal.
Scholarship Deadline: September 14 2010
Discounted Abstract Deadline: September 14 2010
Abstract Deadline: October 11 2010
Discounted Registration Deadline: November 8 2010
We gratefully acknowledge additional support for this conference from:

Anita Roberts Memorial Fund
Cell Signaling Technology, Inc.Genzyme CorporationImClone Systems CorporationJDRF
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genzyme Corporation
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI091030-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Friday, January 07 | 3:00PM - 7:30PM
Registration
Room: Ballroom Lobby


Friday, January 07 | 6:15PM - 7:15PM
Refreshments
Room: Superior/Superior Lobby


Friday, January 07 | 7:15PM - 7:45PM
Orientation and Overview
Room: Ballroom 2-3

Speaker 1 of 2
* Wanjun Chen, NIDCR, National Institutes of Health, USA

Friday, January 07 | 7:15PM - 7:45PM
Orientation and Overview
Room: Ballroom 2-3

Speaker 2 of 2
Michael B. Sporn, Dartmouth Medical School, USA
The Discovery of TGF-beta

Friday, January 07 | 7:45PM - 8:45PM
Opening Remarks and Keynote Address
Room: Ballroom 2-3

Speaker 1 of 1
Joan Massagué, Memorial Sloan Kettering Cancer Center, USA
TGF-beta Receptors, Mediators and Targets

Saturday, January 08 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Saturday, January 08 | 8:00AM - 11:00AM
Basic Mechanisms of TGF-beta Signal Transduction
Room: Ballroom 2-3

Speaker 1 of 5
* Rik Derynck, University of California, San Francisco, USA
TGF-beta-Induced Smad and Non-Smad Signaling Pathways

Saturday, January 08 | 8:00AM - 11:00AM
Basic Mechanisms of TGF-beta Signal Transduction
Room: Ballroom 2-3

Speaker 2 of 5
Daniel B. Rifkin, New York University, USA
TGF-beta Bioavailability: Latency and Activation

Saturday, January 08 | 8:00AM - 11:00AM
Basic Mechanisms of TGF-beta Signal Transduction
Room: Ballroom 2-3

Speaker 3 of 5
Xin-Hua Feng, Baylor College of Medicine, USA
Molecular Basis of Smad Signal Transduction and Termination

Saturday, January 08 | 8:00AM - 11:00AM
Basic Mechanisms of TGF-beta Signal Transduction
Room: Ballroom 2-3

Speaker 4 of 5
Caroline S. Hill, Francis Crick Institute, UK
Regulation of TGF-beta and BMP Signalling Pathways

Saturday, January 08 | 8:00AM - 11:00AM
Basic Mechanisms of TGF-beta Signal Transduction
Room: Ballroom 2-3

Speaker 5 of 5
Gerald J. Prud'homme, St. Michael's Hospital, Canada
Short Talk: Neuropilin-1 Exerts TGF-beta Activating and Coreceptor Functions

Saturday, January 08 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Lobby


Saturday, January 08 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Saturday, January 08 | 11:00AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby


Saturday, January 08 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby


Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 1 of 9
* Herman Waldmann, University of Oxford, UK

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 2 of 9
Nathalie Schmitt, Baylor Institute for Immunology Research, USA
Activated Dendritic Cells Promote the Generation of Human T Follicular Helper Cells in Collaboration with TGF-beta

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 3 of 9
Shomyseh Sanjabi, Gladstone Institutes, University of California, San Francisco, USA
TGF-beta Signaling in CD8+ T Cell Biology

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 4 of 9
Mizuko Mamura, Gachon University of Medicine and Science, South Korea
Divergent Roles of Smad2 and Smad3 in Stat Activation in Arthritogenic T Helper 17 Cells

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 5 of 9
Erica L. Stone, Wistar Institute, USA
Foxo1 Controls T Regulatory Cell Development and Function

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 6 of 9
Julie Stockis, CRUK-CI, UK
Membrane Protein GARP is a Receptor for Latent TGF-beta on the Surface of Activated Human Treg

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 7 of 9
Frederico S. Regateiro, University of Oxford, UK
Anti-Inflammatory Adenosine Generation by Leukocytes is Tightly Regulated by TGF-beta and is Independent of Foxp3

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 8 of 9
William A. Faubion, Mayo Clinic, USA
Antigen Oxidation Converts the Established TGFbeta Suppressive Effect on Naïve T Cells to an Immunostimulatory Effect Leading to the Generation of Treg Cells

Saturday, January 08 | 2:30PM - 4:30PM
Workshop 1: TGF-beta and Other Cytokines in T Cell Developme
nt, Differentiation
Room: Ballroom 2-3

Speaker 9 of 9
Joanne E. Konkel, University of Manchester, UK
TGF-beta is Required for Foxp3 Induction in Thymocytes

Saturday, January 08 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Saturday, January 08 | 5:00PM - 7:15PM
TGF-beta Regulation of T and B Cell Function
Room: Ballroom 2-3

Speaker 1 of 4
* Richard A. Flavell, HHMI/Yale University School of Medicine, USA
TGF-beta in CD4 and CD8 T Cells

Saturday, January 08 | 5:00PM - 7:15PM
TGF-beta Regulation of T and B Cell Function
Room: Ballroom 2-3

Speaker 2 of 4
Tim R. Mosmann, University of Rochester Medical Center, USA
Long- and Short-Term Regulation of T Cell Cytokine Patterns

Saturday, January 08 | 5:00PM - 7:15PM
TGF-beta Regulation of T and B Cell Function
Room: Ballroom 2-3

Speaker 3 of 4
Alexander Y. Rudensky, HHMI/Memorial Sloan Kettering Cancer Center, USA
TGF-beta Regulation of T Cells: Treg-Dependent and -Independent Pathways

Saturday, January 08 | 5:00PM - 7:15PM
TGF-beta Regulation of T and B Cell Function
Room: Ballroom 2-3

Speaker 4 of 4
Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA
Role of TGF-beta in Inducing Novel T Cell Subsets

Saturday, January 08 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby


Saturday, January 08 | 7:30PM - 10:00PM
Poster Session 1
Room: Superior/Superior Lobby


Sunday, January 09 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Sunday, January 09 | 8:00AM - 11:00AM
TGF-beta and Regulatory T Cells
Room: Ballroom 2-3

Speaker 1 of 5
Wanjun Chen, NIDCR, National Institutes of Health, USA
The Molecular Mechanisms in TGF-beta Induction of Foxp3 Gene

Sunday, January 09 | 8:00AM - 11:00AM
TGF-beta and Regulatory T Cells
Room: Ballroom 2-3

Speaker 2 of 5
* Ethan M. Shevach, NIAID, National Institutes of Health, USA
Control of Immune Response by TGF-beta Induced Treg Cells

Sunday, January 09 | 8:00AM - 11:00AM
TGF-beta and Regulatory T Cells
Room: Ballroom 2-3

Speaker 3 of 5
Li Yang, NCI, National Institutes of Health, USA

Sunday, January 09 | 8:00AM - 11:00AM
TGF-beta and Regulatory T Cells
Room: Ballroom 2-3

Speaker 4 of 5
Julien C. Marie, INSERM/Cancer Research Center of Lyon, France
Short Talk: The Fate of Natural Regulatory T Cells is Dictated by Transforming Growth Factor Beta Signaling

Sunday, January 09 | 8:00AM - 11:00AM
TGF-beta and Regulatory T Cells
Room: Ballroom 2-3

Speaker 5 of 5
Hongbo Chi, St. Jude Children's Research Hospital, USA
Short Talk: S1P1-mTOR Axis Directs the Reciprocal Differentiation of TH1 and Regulatory T Cells by Antagonizing TGF-beta-Smad3 Signaling

Sunday, January 09 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Lobby


Sunday, January 09 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Sunday, January 09 | 11:15AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby


Sunday, January 09 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby


Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 1 of 8
* Lucienne Chatenoud, INSERM U1151, Hôpital Necker-Enfants Malades, France

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 2 of 8
Sylvain Perruche, Etablissement Français du Sang BFC, France
TGF-beta-Exposed Plasmacytoid Dendritic Cells Participate to Th17 Commitment

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 3 of 8
Tom Simones, University of Montana, USA
Aryl Hydrocarbon Receptor-Activated Dendritic Cells Generate CD4+ CD25+ FoxP3+ Regulatory T Cells

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 4 of 8
Junda M. Kel, Erasmus Medical Center, Netherlands
TGF-beta Controls Dendritic Cell Function to Maintain Self Tolerance

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 5 of 8
Aleh Bobr, University of Minnesota, USA
Autocrine TGF-beta is Required to Maintain Langerhans Cell Immaturity

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 6 of 8
Andrew C. Melton, BioMarin, USA
Activation of TGF-beta by Integrin alpha(v)beta8 on Dendritic Cells is Required for Th17 Development in Mice

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 7 of 8
Rajalakshmy Ramalingam, University of Arizona, USA
Lack of TGF-beta Signaling in Dendritic Cells Leads to Multiorgan Autoimmune Inflammatory Disease

Sunday, January 09 | 2:30PM - 4:30PM
Workshop 2: TGF-beta Effects on Antigen-Presenting Cells
Room: Ballroom 2-3

Speaker 8 of 8
Dominika G. Lukas, Institut für Molekulare Medizin, Germany
Conditional Deletion of the TGFbeta Inhibitor Smad7 in T Cells or Dendritic Cells Limits Autoimmune CNS Inflammation by Induction of Regulatory T Cells

Sunday, January 09 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Sunday, January 09 | 5:00PM - 7:15PM
TGF-beta in Innate Immunity
Room: Ballroom 2-3

Speaker 1 of 5
Steven M. Albelda, University of Pennsylvania, USA
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-beta: Implications for Anti-Tumor Immunity



Sunday, January 09 | 5:00PM - 7:15PM
TGF-beta in Innate Immunity
Room: Ballroom 2-3

Speaker 2 of 5
* Yasmine Belkaid, NIAID, National Institutes of Health, USA
Mucosal DCs and TGF-beta in Infection

Sunday, January 09 | 5:00PM - 7:15PM
TGF-beta in Innate Immunity
Room: Ballroom 2-3

Speaker 3 of 5
Peter M. Henson, National Jewish Health Center and University of Colorado Denver, USA
TGF-beta as a Mediator of Responses to Apoptotic Cells

Sunday, January 09 | 5:00PM - 7:15PM
TGF-beta in Innate Immunity
Room: Ballroom 2-3

Speaker 4 of 5
Herbert Strobl, Medical University Graz, Austria
Short Talk: Transcriptional Mechanism Underlying TGF-beta1- Dependent Langerhans Dendritic Cell Differentiation: A Key Role of KLF4

Sunday, January 09 | 5:00PM - 7:15PM
TGF-beta in Innate Immunity
Room: Ballroom 2-3

Speaker 5 of 5
Alexei Gratchev, University Medical Center Mannheim, University of Heidelberg, Germany
Short Talk: TGF-beta Signaling in Macrophages

Sunday, January 09 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby


Sunday, January 09 | 7:30PM - 10:00PM
Poster Session 2
Room: Superior/Superior Lobby


Monday, January 10 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Monday, January 10 | 8:00AM - 11:15AM
TGF-beta and Th17 and Th9 Cells
Room: Ballroom 2-3

Speaker 1 of 6
* Dan R. Littman, HHMI/New York University School of Medicine, USA
TGF-beta and RORgammaT in Murine and Human T Cells

Monday, January 10 | 8:00AM - 11:15AM
TGF-beta and Th17 and Th9 Cells
Room: Ballroom 2-3

Speaker 2 of 6
Matthias G. von Herrath, Novo Nordisk and La Jolla Institute for Allergy and Immunology, USA
TGF-beta and Ox40 Modulation Enhance Virus-Specific T Cell Responses in a Chronic Virus Infection Model

Monday, January 10 | 8:00AM - 11:15AM
TGF-beta and Th17 and Th9 Cells
Room: Ballroom 2-3

Speaker 3 of 6
Tobias Bopp, University Medical Center of the Johannes Gutenberg-University, Germany
TGF-beta Promotes IRF4-Dependent Development of IL-9-Producing Th9 Cells

Monday, January 10 | 8:00AM - 11:15AM
TGF-beta and Th17 and Th9 Cells
Room: Ballroom 2-3

Speaker 4 of 6
David A. Hafler, Yale University School of Medicine, USA
A Role for TGF-beta in Human IL-9 Producing TH17 Cells

Monday, January 10 | 8:00AM - 11:15AM
TGF-beta and Th17 and Th9 Cells
Room: Ballroom 2-3

Speaker 5 of 6
Ming O. Li, Memorial Sloan Kettering Cancer Center, USA
Short Talk: Autocrine TGF-beta1 Promotes in vivo Th17 Cell Differentiation

Monday, January 10 | 8:00AM - 11:15AM
TGF-beta and Th17 and Th9 Cells
Room: Ballroom 2-3

Speaker 6 of 6
Akihiko Yoshimura, Keio University, Japan
Short Talk: Role of TGF-beta-Smad2/3 Dependent and Independent Signaling in Helper T Cell Function and Differentiation

Monday, January 10 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Lobby


Monday, January 10 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Monday, January 10 | 11:15AM - 1:00PM
Poster Setup
Room: Superior/Superior Lobby


Monday, January 10 | 1:00PM - 10:00PM
Poster Viewing
Room: Superior/Superior Lobby


Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 1 of 9
* Wanjun Chen, NIDCR, National Institutes of Health, USA

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 2 of 9
Song Guo Zheng, University of Southern California, USA
Therapeutic Effects of TGF-beta-Induced Regulatory T Cells on the Established Autoimmune Diseases

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 3 of 9
Kristian P. Doyle, University of Arizona, USA
TGFbeta Signaling Increases in Aging and Signals to Innate Immune Cells in the Weeks after Stroke

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 4 of 9
Daniel A. Kahn, David Geffen School of Medicine, University of California Los Angeles, USA
Pregnancy Dramatically Enhances T Regulatory Cell Function

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 5 of 9
Troy D. Cline, St. Jude Children's Research Hospital, USA
Activation of TGF-beta by Influenza Virus Neuraminidase and its Role in Influenza Virus Pathogenesis

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 6 of 9
Hong-Hua Mu, University of Utah School of Medicine, USA
Blockade of Plasminogen-Activator Inhibitor Type-1 Results in TGF-beta-Mediated Suppression of Lethal Toxicity by Mycoplasma Arthritidis

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 7 of 9
Petr Nachtigal, Charles University in Prague, Czech Republic
Endoglin (Type III TGF-beta Receptor) Expression is Related to Decreased Atherogenesis in ApoE/LDLR Double Knockout Mice

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 8 of 9
Erica B. Wilson, Leeds Institute of Molecular Medicine, UK
Ovarian Tumor Microenvironment Associated Modulation of Natural Killer Cells

Monday, January 10 | 2:30PM - 4:30PM
Workshop 3: TGF-beta in Autoimmune Diseases, Infection and C
ancer
Room: Ballroom 2-3

Speaker 9 of 9
Stephen H. Bartelmez, BetaStem Therapeutics, USA
Transient Inhibition of Transforming Growth Factor-Beta-1 in Human Blood-Derived CD34+ Cells Enhances Vascular Reparative Functions In Vivo

Monday, January 10 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Monday, January 10 | 5:00PM - 7:15PM
TGF-beta in Mucosal Immunity and Tolerance
Room: Ballroom 2-3

Speaker 1 of 4
* Howard L. Weiner, Brigham and Women’s Hospital, Harvard Medical School, USA
Induction of Tregs by Mucosal Administration of Aryl Hydrocarbon Receptor Ligands and Anti-CD3 Monoclonal Antibody in Animals and Humans

Monday, January 10 | 5:00PM - 7:15PM
TGF-beta in Mucosal Immunity and Tolerance
Room: Ballroom 2-3

Speaker 2 of 4
Fiona M. Powrie, University of Oxford, UK
Regulation of IBD by TGF-beta

Monday, January 10 | 5:00PM - 7:15PM
TGF-beta in Mucosal Immunity and Tolerance
Room: Ballroom 2-3

Speaker 3 of 4
Warren Strober, National Institutes of Health, USA
Molecular Regulation of TGF-beta/Retinoic Acid Induction of Foxp3 Expression

Monday, January 10 | 5:00PM - 7:15PM
TGF-beta in Mucosal Immunity and Tolerance
Room: Ballroom 2-3

Speaker 4 of 4
Xiao-Jing Wang, University of Colorado Denver, USA
Short Talk: Role of TGFbeta1 in Inflammation in Skin and Oral Mucosa

Monday, January 10 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Superior/Superior Lobby


Monday, January 10 | 7:30PM - 10:00PM
Poster Session 3
Room: Superior/Superior Lobby


Tuesday, January 11 | 7:00AM - 8:00AM
Breakfast
Room: Golden Cliff/Eagles


Tuesday, January 11 | 8:00AM - 11:15AM
TGF-beta in Autoimmunity, Inflammation and Transplantation
Room: Ballroom 2-3

Speaker 1 of 6
Dean Sheppard, University of California, San Francisco, USA
Regulation of T Cell Differentiation by the alphavbeta8 Integrin on Dendritic Cells

Tuesday, January 11 | 8:00AM - 11:15AM
TGF-beta in Autoimmunity, Inflammation and Transplantation
Room: Ballroom 2-3

Speaker 2 of 6
Herman Waldmann, University of Oxford, UK
TGF-beta Signaling to T Cells in Long-Term Acceptance of Allografts

Tuesday, January 11 | 8:00AM - 11:15AM
TGF-beta in Autoimmunity, Inflammation and Transplantation
Room: Ballroom 2-3

Speaker 3 of 6
Lucienne Chatenoud, INSERM U1151, Hôpital Necker-Enfants Malades, France
CD3-Antibody, TGF-beta and Tregs in Type I Diabetes

Tuesday, January 11 | 8:00AM - 11:15AM
TGF-beta in Autoimmunity, Inflammation and Transplantation
Room: Ballroom 2-3

Speaker 4 of 6
* John J. O'Shea, NIAMS, National Institutes of Health, USA
TGF-beta and Furin in T Cells

Tuesday, January 11 | 8:00AM - 11:15AM
TGF-beta in Autoimmunity, Inflammation and Transplantation
Room: Ballroom 2-3

Speaker 5 of 6
Mark A. Travis, University of Manchester, UK
Short Talk: Lack of Integrin-Mediated TGF-beta Activation by Dendritic Cells Results in Protection from Chronic Gastrointestinal Parasite Infection

Tuesday, January 11 | 8:00AM - 11:15AM
TGF-beta in Autoimmunity, Inflammation and Transplantation
Room: Ballroom 2-3

Speaker 6 of 6
Bapi Pahar, Tulane National Primate Research Center, USA
Short Talk: TGF-beta and IL-10 Produced by Regulatory B Cells are TLR2 Dependent and are Capable in Suppressing Th1 Responses

Tuesday, January 11 | 9:20AM - 9:40AM
Coffee Break
Room: Ballroom Lobby


Tuesday, January 11 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Tuesday, January 11 | 4:30PM - 5:00PM
Coffee Available
Room: Ballroom Lobby


Tuesday, January 11 | 5:00PM - 7:00PM
TGF-beta in Human Immune Cells and Diseases
Room: Ballroom 2-3

Speaker 1 of 4
Dario A. A. Vignali, University of Pittsburgh School of Medicine, USA
Induced Regulatory T Cells: Novel Populations and Clinical Implications

Tuesday, January 11 | 5:00PM - 7:00PM
TGF-beta in Human Immune Cells and Diseases
Room: Ballroom 2-3

Speaker 2 of 4
Michael B. Sporn, Dartmouth Medical School, USA
Synthetic Triterpenoids and Inflammatory Diseases: Interactions with Immune Cells and TGF-beta

Tuesday, January 11 | 5:00PM - 7:00PM
TGF-beta in Human Immune Cells and Diseases
Room: Ballroom 2-3

Speaker 3 of 4
* John M. McPherson, Genzyme Corporation, USA
Safety Considerations for the Clinical Use of Anti-TGF-beta Antibodies for Treatment of Fibrotic Diseases and Cancer

Tuesday, January 11 | 5:00PM - 7:00PM
TGF-beta in Human Immune Cells and Diseases
Room: Ballroom 2-3

Speaker 4 of 4
Hideki Ueno, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Subsets of Human Blood CXCR5+ CD4+ T Cells and their Alteration in Autoimmune Disease

Tuesday, January 11 | 7:00PM - 8:15PM
Social Hour with Lite Bites
Room: Ballroom 2-3


Tuesday, January 11 | 8:00PM - 11:00PM
Entertainment
Room: Ballroom 2-3


Tuesday, January 11 | 8:00PM - 11:00PM
Cash Bar
Room: Ballroom 2-3


Wednesday, January 12 | 10:22AM - 10:22AM
Departure


*Session Chair
†Invited, not yet responded.