Web Desc
Stem Cells in Development, Tissue Homeostasis and Disease
Organizer(s): Ronald D. McKay, Elaine Fuchs and Thea D. Tlsty
Date: January 30 - February 04, 2011
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Sponsored by Novartis Institutes for BioMedical Research, Pfizer Inc. and Sangamo BioSciences, Inc.
Summary of Meeting:
This meeting is focussed on the mechanisms controlling stem cells throughout life. The presentations will define the different pluripotent cells in the early embryo and the signals that lead them into the many distinct cell types that co-operate to form an adult organism. An exciting aspect of the field is that as we define the shared mechanisms controlling different tissues, we will generate an integrated view of human development. This symposium is designed to present key advances that are leading to a systematic understanding of the biology of human tissues throughout life. In this program, we strive to balance recognized problems in the stem cell field and new ideas that will functionalize human genetic and cellular diversity providing a new understanding of developmental decisions and tissue repair. The presentations will form a strong platform for all the participants to discuss new technologies that identify the central regulators of development and treat disease.
Scholarship Deadline: September 30 2010
Discounted Abstract Deadline: September 30 2010
Abstract Deadline: November 2 2010
Discounted Registration Deadline: November 30 2010
We gratefully acknowledge additional support for this conference from:
Aastrom Biosciences, Inc.Biospherix, Ltd.Cell Signaling Technology, Inc.March of Dimes FoundationNovartis Institutes for BioMedical ResearchPfizer Inc.Sangamo BioSciences, Inc.STEMCELL Technologies, Inc.StemgentThe Company of Biologists LtdThe Rockefeller University Press - The Journal of Cell BiologyThe Rockefeller University Press - The Journal of Experimental Medicine
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

EMBO Young Investigator Programme


Atsushi Kitani

Hiroshi Nishimune
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
S. Karger AG - Cells Tissues Organs
We gratefully acknowledge the generous grant for this conference provided by:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Grant No. 1R13HD068073-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 30 | 3:00PM - 7:30PM
Registration
Room: Zia Concourse


Sunday, January 30 | 6:15PM - 7:15PM
Refreshments
Room: Zia Concourse


Sunday, January 30 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Anasazi Ballroom

Speaker 1 of 2
* Gordon M. Keller, University Health Network, MaRS Centre, Canada

Sunday, January 30 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Anasazi Ballroom

Speaker 2 of 2
Elizabeth J. Robertson, University of Oxford, UK
Pathways Regulating Specification of Progenitor Populations during Gastrulation

Monday, January 31 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Monday, January 31 | 8:00AM - 11:00AM
Pluripotent Cells and the Primitive Streak
Room: Anasazi Ballroom

Speaker 1 of 5
Austin Smith, University of Cambridge, UK
Maintaining the Pluripotent State

Monday, January 31 | 8:00AM - 11:00AM
Pluripotent Cells and the Primitive Streak
Room: Anasazi Ballroom

Speaker 2 of 5
Azim Surani, University of Cambridge, UK
Genetic and Epigenetic Regulators of the Germline and Pluripotency

Monday, January 31 | 8:00AM - 11:00AM
Pluripotent Cells and the Primitive Streak
Room: Anasazi Ballroom

Speaker 3 of 5
Kathryn V. Anderson, Memorial Sloan-Kettering Cancer Center, USA
Genetic Control of Cell Fate and Behavior in the Mouse Primitive Streak

Monday, January 31 | 8:00AM - 11:00AM
Pluripotent Cells and the Primitive Streak
Room: Anasazi Ballroom

Speaker 4 of 5
* Peter W. Reddien, Whitehead Institute, USA
An Adult Pluripotent Stem Cell Drives Planarian Regeneration

Monday, January 31 | 8:00AM - 11:00AM
Pluripotent Cells and the Primitive Streak
Room: Anasazi Ballroom

Speaker 5 of 5
Masayo Sakaki-Yumoto, University of California San Francisco, USA
Short Talk: Differential Roles of Smad2 and Smad3 in Human Embryonic Stem Cell Pluripotency

Monday, January 31 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Monday, January 31 | 11:00AM - 1:00PM
Poster Setup
Room: Sunset Room/Eldorado Court


Monday, January 31 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Monday, January 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room/Eldorado Court


Monday, January 31 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Monday, January 31 | 5:00PM - 7:00PM
Cell Lineages and Disease
Room: Anasazi Ballroom

Speaker 1 of 6
* Elaine V. Fuchs, Rockefeller University, USA

Monday, January 31 | 5:00PM - 7:00PM
Cell Lineages and Disease
Room: Anasazi Ballroom

Speaker 2 of 6
* Valentina Greco, Yale School of Medicine, USA

Monday, January 31 | 5:00PM - 7:00PM
Cell Lineages and Disease
Room: Anasazi Ballroom

Speaker 3 of 6
Lorenz Studer, Memorial Sloan Kettering Cancer Center, USA
Modeling Human Neural Development and Disease in Pluripotent Stem Cells

Monday, January 31 | 5:00PM - 7:00PM
Cell Lineages and Disease
Room: Anasazi Ballroom

Speaker 4 of 6
Elly M. Tanaka, IMP - Research Institute of Molecular Pathology, Austria
Applying Regenerative Concepts for the CNS from the Salamander to Mammalian Neural Stem Cells

Monday, January 31 | 5:00PM - 7:00PM
Cell Lineages and Disease
Room: Anasazi Ballroom

Speaker 5 of 6
Richard A. Young, Whitehead Institute for Biomedical Research, USA
Transcriptional Control, Chromosome Structure and Disease

Monday, January 31 | 5:00PM - 7:00PM
Cell Lineages and Disease
Room: Anasazi Ballroom

Speaker 6 of 6
Fredrik Lanner, Karolinska Institutet, Sweden
Short Talk: Cell Surface Proteomics of Blastocyst-Derived Cells Enables Flow-Cytometric Isolation of Blastocyst Lineages

Monday, January 31 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Monday, January 31 | 7:30PM - 10:00PM
Poster Session 1
Room: Sunset Room/Eldorado Court


Tuesday, February 01 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Tuesday, February 01 | 8:00AM - 11:00AM
Self-Renewal through the Life-Span
Room: Anasazi Ballroom

Speaker 1 of 6
* Margaret A. Goodell, Baylor College of Medicine, USA

Tuesday, February 01 | 8:00AM - 11:00AM
Self-Renewal through the Life-Span
Room: Anasazi Ballroom

Speaker 2 of 6
Sean J. Morrison, University of Texas Southwestern Medical Center, USA
Developmental Changes in the Regulation of PI3 Kinase Signaling Lead to Developmental Changes in HSC Self-Renewal and Leukemogenesis mechanisms

Tuesday, February 01 | 8:00AM - 11:00AM
Self-Renewal through the Life-Span
Room: Anasazi Ballroom

Speaker 3 of 6
Amy J. Wagers, Harvard University, USA
Skeletal Muscle Regeneration

Tuesday, February 01 | 8:00AM - 11:00AM
Self-Renewal through the Life-Span
Room: Anasazi Ballroom

Speaker 4 of 6
Peter M. Lansdorp, BC Cancer Research Center, Canada
Telomeres, Stem Cells and Bone Marrow Failure

Tuesday, February 01 | 8:00AM - 11:00AM
Self-Renewal through the Life-Span
Room: Anasazi Ballroom

Speaker 5 of 6
Ronald A. DePinho, University of Texas MD Anderson Cancer Center, USA
Telomeres in Cancer and Aging

Tuesday, February 01 | 8:00AM - 11:00AM
Self-Renewal through the Life-Span
Room: Anasazi Ballroom

Speaker 6 of 6
Tudorita (Doina) Tumbar, Cornell University, USA
Short Talk: Runx1 is a Master Regulator of Adult Hair Follicle Stem Cells Activation, Emergence, and Maintenance, and Promotes Skin Tumorigenesis

Tuesday, February 01 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Tuesday, February 01 | 11:00AM - 1:00PM
Poster Setup
Room: Sunset Room/Eldorado Court


Tuesday, February 01 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Tuesday, February 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room/Eldorado Court


Tuesday, February 01 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Tuesday, February 01 | 5:00PM - 7:00PM
Global Genetic and Epigenetic Data Sets
Room: Anasazi Ballroom

Speaker 1 of 4
* Peter M. Lansdorp, BC Cancer Research Center, Canada

Tuesday, February 01 | 5:00PM - 7:00PM
Global Genetic and Epigenetic Data Sets
Room: Anasazi Ballroom

Speaker 2 of 4
Ronald D. McKay, Lieber Institute for Brain Development, USA
Controlling Mouse and Human Stem Cells

Tuesday, February 01 | 5:00PM - 7:00PM
Global Genetic and Epigenetic Data Sets
Room: Anasazi Ballroom

Speaker 3 of 4
Hugo Snippert, Hubrecht Institute, Netherlands
Short Talk : Intestinal Stem Cell Self-Renewal

Tuesday, February 01 | 5:00PM - 7:00PM
Global Genetic and Epigenetic Data Sets
Room: Anasazi Ballroom

Speaker 4 of 4
Angie Rizzino, University of Nebraska Medical Center, USA
Short Talk: SOX2 Protein Levels Regulate the Fate of Embryonic Stem (ES) Cells

Tuesday, February 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Tuesday, February 01 | 7:30PM - 10:00PM
Poster Session 2
Room: Sunset Room/Eldorado Court


Wednesday, February 02 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Wednesday, February 02 | 8:00AM - 11:00AM
Stem Cells Interactions in the Niche
Room: Anasazi Ballroom

Speaker 1 of 6
* Elly M. Tanaka, IMP - Research Institute of Molecular Pathology, Austria

Wednesday, February 02 | 8:00AM - 11:00AM
Stem Cells Interactions in the Niche
Room: Anasazi Ballroom

Speaker 2 of 6
Tannishtha Reya, University of California, San Diego, USA
Control of Cell Fate by Developmental Signals

Wednesday, February 02 | 8:00AM - 11:00AM
Stem Cells Interactions in the Niche
Room: Anasazi Ballroom

Speaker 3 of 6
Leonard I. Zon, HHMI/Boston Children's Hospital, USA
Signaling Pathways and Transcriptional Control of Hematopoiesis

Wednesday, February 02 | 8:00AM - 11:00AM
Stem Cells Interactions in the Niche
Room: Anasazi Ballroom

Speaker 4 of 6
Elaine V. Fuchs, Rockefeller University, USA
Skin Stem Cells in Silence and Action

Wednesday, February 02 | 8:00AM - 11:00AM
Stem Cells Interactions in the Niche
Room: Anasazi Ballroom

Speaker 5 of 6
Sergei Y. Sokol, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Canonical Wnt Signaling

Wednesday, February 02 | 8:00AM - 11:00AM
Stem Cells Interactions in the Niche
Room: Anasazi Ballroom

Speaker 6 of 6
Thea D. Tlsty, University of California, San Francisco, USA
Human Cells with Extensive Plasticity

Wednesday, February 02 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Wednesday, February 02 | 11:00AM - 1:00PM
Poster Setup
Room: Sunset Room/Eldorado Court


Wednesday, February 02 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Wednesday, February 02 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room/Eldorado Court


Wednesday, February 02 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Wednesday, February 02 | 5:00PM - 7:00PM
Systems Approaches to Stem Cell Fate Choice
Room: Anasazi Ballroom

Speaker 1 of 5
* Elizabeth J. Robertson, University of Oxford, UK

Wednesday, February 02 | 5:00PM - 7:00PM
Systems Approaches to Stem Cell Fate Choice
Room: Anasazi Ballroom

Speaker 2 of 5
Jürgen A. Knoblich, Institute of Molecular Biotechnology, Austria
Asymmetric Cell Division and Tumorigenesis in Neural Stem Cell Lineages

Wednesday, February 02 | 5:00PM - 7:00PM
Systems Approaches to Stem Cell Fate Choice
Room: Anasazi Ballroom

Speaker 3 of 5
Gordon M. Keller, University Health Network, MaRS Centre, Canada
Potential of Pluripotent Stem Cells

Wednesday, February 02 | 5:00PM - 7:00PM
Systems Approaches to Stem Cell Fate Choice
Room: Anasazi Ballroom

Speaker 4 of 5
Simon Fortier, Institute for Research in Immunology and Cancer (IRIC), Canada
Short Talk: Identification of Embryonic Stem Cell Fate Determinants

Wednesday, February 02 | 5:00PM - 7:00PM
Systems Approaches to Stem Cell Fate Choice
Room: Anasazi Ballroom

Speaker 5 of 5
Ian Chambers, University of Edinburgh, UK
Short Talk: The Developmental Dismantling of Pluripotency and its Reversal

Wednesday, February 02 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Wednesday, February 02 | 7:30PM - 10:00PM
Poster Session 3
Room: Sunset Room/Eldorado Court


Thursday, February 03 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Thursday, February 03 | 8:00AM - 11:00AM
The Lineage Origin of Cancer
Room: Anasazi Ballroom

Speaker 1 of 6
* Thea D. Tlsty, University of California, San Francisco, USA

Thursday, February 03 | 8:00AM - 11:00AM
The Lineage Origin of Cancer
Room: Anasazi Ballroom

Speaker 2 of 6
Cédric Blanpain, Universite Libre de Bruxelles, Belgium
EMBO Young Investigator Lecture: Uncovering the Cell Lineages at the Origin of Skin Cancers

Thursday, February 03 | 8:00AM - 11:00AM
The Lineage Origin of Cancer
Room: Anasazi Ballroom

Speaker 3 of 6
Margaret A. Goodell, Baylor College of Medicine, USA
Regulation of Hematopoietic Stem Cells

Thursday, February 03 | 8:00AM - 11:00AM
The Lineage Origin of Cancer
Room: Anasazi Ballroom

Speaker 4 of 6
Irving L. Weissman, Stanford University, USA
Normal and Neoplastic Stem Cells

Thursday, February 03 | 8:00AM - 11:00AM
The Lineage Origin of Cancer
Room: Anasazi Ballroom

Speaker 5 of 6
Irina M. Conboy, University of California, Berkeley, USA
Signal Transduction in Adult Stem Cells or how to Reverse Stem Cell Aging

Thursday, February 03 | 8:00AM - 11:00AM
The Lineage Origin of Cancer
Room: Anasazi Ballroom

Speaker 6 of 6
Patricia K. Donahoe, Massachusetts General Hospital, USA
Short Talk: Müllerian Inhibiting Substance and its Anthrapyrazolone Mimetic Preferentially Inhibit a Stem/Progenitor Cell Enriched Population in Human Ovarian Cancer Cell Lines Compared to Chemotherapeutic Agents

Thursday, February 03 | 9:00AM - 9:20AM
Coffee Break
Room: Zia Concourse


Thursday, February 03 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Thursday, February 03 | 5:30PM - 6:00PM
Coffee Available
Room: Zia Concourse


Thursday, February 03 | 6:00PM - 6:45PM
Using Stem Cell Biology to Model and Treat Disease
Room: Anasazi Ballroom

Speaker 1 of 2
* Ronald D. McKay, Lieber Institute for Brain Development, USA

Thursday, February 03 | 6:00PM - 6:45PM
Using Stem Cell Biology to Model and Treat Disease
Room: Anasazi Ballroom

Speaker 2 of 2
Shahin Rafii, Weill Cornell Medical College, USA
Instructive Endothelial-Derived Angiocrine Signals in Stem Cell Self-Renewal and Organ Regeneration

Thursday, February 03 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room


Thursday, February 03 | 8:00PM - 11:00PM
Entertainment
Room: Eldorado Court/Sunset Room


Thursday, February 03 | 8:00PM - 11:00PM
Cash Bar
Room: Eldorado Court/Sunset Room


Friday, February 04 | 10:25AM - 10:25AM
Departure


*Session Chair.