Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
DNA Replication and Genome Instability: From Mechanism to Disease (2019A1)
DNA Replication and Recombination (2017Z2)
DNA Replication and Recombination (2015X3)
DNA Replication and Recombination (2013X5)

Web Desc
DNA Replication and Recombination Organizer(s): Peter M. Burgers, Lorraine S. Symington and Johannes Walter Date: February 27 - March 04, 2011 Location: Keystone Resort, Keystone, CO, USA Supported by the Directors' Fund Summary of Meeting: As the pathways that govern DNA replication and DNA recombination are better defined, there is exciting progress in our understanding of the basic mechanisms of these processes. There is also growing evidence that replication and recombination are intimately connected in order to resolve problems arising during DNA replication, and to define outcomes with respect to chromosome integrity. This meeting will integrate mechanistic insights from biochemical studies with cellular pathways that control DNA replication initiation and progression, DNA recombination, and responses to DNA damage. Specific plenary sessions will focus on DNA replication mechanisms in prokaryotes and eukaryotes. Recombination sessions will present progress in our understanding of the mechanisms underlying mitotic recombination, and on recombination-based responses to replication stress and DNA damage. Sessions will also address cell cycle checkpoint and chromatin structural responses to DNA damage. The plenary sessions will be conducted by invited speakers and speakers selected from submitted abstracts. In addition, four related workshops will be conducted, with short talks selected from submitted abstracts. Scholarship Deadline: October 27 2010 Discounted Abstract Deadline: October 27 2010 Abstract Deadline: November 30 2010 Discounted Registration Deadline: December 29 2010 We gratefully acknowledge additional support for this conference from: Francesca Storici We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

DNA Replication and Recombination

Organizer(s): Peter M. Burgers, Lorraine S. Symington and Johannes Walter

Date: February 27 - March 04, 2011
Location: Keystone Resort, Keystone, CO, USA

Supported by the Directors' Fund

Summary of Meeting:

As the pathways that govern DNA replication and DNA recombination are better defined, there is exciting progress in our understanding of the basic mechanisms of these processes. There is also growing evidence that replication and recombination are intimately connected in order to resolve problems arising during DNA replication, and to define outcomes with respect to chromosome integrity. This meeting will integrate mechanistic insights from biochemical studies with cellular pathways that control DNA replication initiation and progression, DNA recombination, and responses to DNA damage. Specific plenary sessions will focus on DNA replication mechanisms in prokaryotes and eukaryotes. Recombination sessions will present progress in our understanding of the mechanisms underlying mitotic recombination, and on recombination-based responses to replication stress and DNA damage. Sessions will also address cell cycle checkpoint and chromatin structural responses to DNA damage. The plenary sessions will be conducted by invited speakers and speakers selected from submitted abstracts. In addition, four related workshops will be conducted, with short talks selected from submitted abstracts.

Scholarship Deadline: October 27 2010

Discounted Abstract Deadline: October 27 2010

Abstract Deadline: November 30 2010

Discounted Registration Deadline: December 29 2010

We gratefully acknowledge additional support for this conference from:

Francesca Storici

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, February 27 \| 3:00PM - 7:30PM Registration Room: Longs Peak Foyer
Sunday, February 27 \| 6:15PM - 7:15PM Refreshments Room: Longs Peak Foyer
Sunday, February 27 \| 7:15PM - 8:30PM Welcome and Keynote Address Room: Longs/Grays Peak Speaker 1 of 1 Stephen C. Kowalczykowski, University of California, Davis, USA Mechanics and Visualization of Recombinational DNA Repair
Monday, February 28 \| 7:00AM - 8:00AM Breakfast Room: Quandary Peak
Monday, February 28 \| 8:00AM - 11:15AM Replication Fidelity and Mutagenesis Room: Longs/Grays Peak Speaker 1 of 6 * Thomas A. Kunkel, NIEHS, National Institutes of Health, USA Generating and Correcting Leading- and Lagging-Strand DNA Replication Errors
Monday, February 28 \| 8:00AM - 11:15AM Replication Fidelity and Mutagenesis Room: Longs/Grays Peak Speaker 2 of 6 Peggy Hsieh, NIDDK, National Institutes of Health, USA DNA Mismatch Excision Repair and Damage Signaling
Monday, February 28 \| 8:00AM - 11:15AM Replication Fidelity and Mutagenesis Room: Longs/Grays Peak Speaker 3 of 6 Erik Johansson, Umeå University, Sweden Short Talk: Mismatch Repair-Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of Pol epsilon
Monday, February 28 \| 8:00AM - 11:15AM Replication Fidelity and Mutagenesis Room: Longs/Grays Peak Speaker 4 of 6 Karen M. Vasquez, University of Texas, Austin, USA DNA Structure and Mutagenesis
Monday, February 28 \| 8:00AM - 11:15AM Replication Fidelity and Mutagenesis Room: Longs/Grays Peak Speaker 5 of 6 Susan T. Lovett, Brandeis University, USA A Template-Switch Mechanism for Muational Hotspots
Monday, February 28 \| 8:00AM - 11:15AM Replication Fidelity and Mutagenesis Room: Longs/Grays Peak Speaker 6 of 6 Andrei Chabes, Umeå University, Sweden Short Talk: Mechanisms of Mutagenesis in vivo Due to Imbalanced dNTP Pools
Monday, February 28 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Monday, February 28 \| 11:15AM - 1:00PM Poster Setup Room: Quandary Peak
Monday, February 28 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Monday, February 28 \| 1:00PM - 10:00PM Poster Viewing Room: Quandary Peak
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 1 of 8 Roxana Georgescu, Rockefeller University, USA Filling the Gaps … at the Replication Fork
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 2 of 8 Christopher D. Downey, University of Colorado, Boulder, USA Chaperoning of a Replicative Polymerase by its Clamp Loader Plays an Integral Role in Initiation Complex Formation
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 3 of 8 Aimee H. Marceau, University of Wisconsin-Madison, USA Structural Identification of the E. coli SSB Binding Site on the Chi/Psi Subassembly of the Clamp-Loader Complex
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 4 of 8 * Sergey Korolev, St. Louis University Medical School, USA RecOR Alter Conformation of SSB-Bound ssDNA
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 5 of 8 Jeehae Park, University of Illinois at Urbana Champaign, USA Reeling in DNA One Nucleotide at a Time: Repetitive Looping Coupled with PcrA Translocation Dismantles RecA Filaments
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 6 of 8 Richard U. Rymer, University of California Berkeley, USA The Structural Basis for Nucleotide Binding by Bacterial Primase
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 7 of 8 Susan E. Tsutakawa, Lawrence Berkeley National Laboratory, USA Recognition of 5’ Flaps by Flap Endonuclease, hFEN1
Monday, February 28 \| 2:30PM - 4:30PM Workshop 1: Nucleic Acid Enzymes Room: Longs/Grays Peak Speaker 8 of 8 Lorena S. Beese, Duke University Medical Center, USA Human Exonuclease I Complexes with DNA: Implications for the Nucleolytic Step in DNA Repair
Monday, February 28 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Monday, February 28 \| 5:00PM - 7:00PM Homologous Recombination Mechanisms Room: Longs/Grays Peak Speaker 1 of 4 * Wolf-Dietrich Heyer, University of California, Davis, USA Formation and Disassembly of the Rad51-ssDNA Filament is Controlled by a Balance of the Rad51 Paralogs Rad55-Rad57 and the Anti-Recombinase Srs2
Monday, February 28 \| 5:00PM - 7:00PM Homologous Recombination Mechanisms Room: Longs/Grays Peak Speaker 2 of 4 Lorraine S. Symington, Columbia University, USA The Mus81-Mms4 and Yen1 Nucleases Promote Reciprocal Exchange during Mitotic Recombination
Monday, February 28 \| 5:00PM - 7:00PM Homologous Recombination Mechanisms Room: Longs/Grays Peak Speaker 3 of 4 Cees Dekker, Delft University of Technology, Netherlands Single Molecule Studies of Recombinase Proteins
Monday, February 28 \| 5:00PM - 7:00PM Homologous Recombination Mechanisms Room: Longs/Grays Peak Speaker 4 of 4 Ilya J. Finkelstein, University of Texas at Austin, USA Short Talk: Single-Molecule Imaging Reveals Mechanisms of how RecBCD Strips DNA-Bound Obstacles
Monday, February 28 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Quandary Peak
Monday, February 28 \| 7:30PM - 10:00PM Poster Session 1 Room: Quandary Peak
Tuesday, March 01 \| 7:00AM - 8:00AM Breakfast Room: Quandary Peak
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 1 of 7 * John F.X. Diffley, Francis Crick Institute, UK Early Events in Eukaryotic DNA Replication
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 2 of 7 Johannes C. Walter, Harvard Medical School, USA Mechanism of the MCM2-7 DNA Helicase
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 3 of 7 Stephen P. Bell, Massachusetts Institute of Technology, USA Short Talk: S. Cerevisiae Origin-Dependent Replication Initiation in vitro: Insights into Kinase Function and Polymerase Loading
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 4 of 7 Michael Botchan, University of California, Berkeley, USA Regulation and Activation of the MCM Helicase
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 5 of 7 Bruce W. Stillman, Cold Spring Harbor Laboratory, USA Multiple Activities For The Origin Recognition Complex (ORC) During The Chromosome Duplication And Segregation Cycle
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 6 of 7 Jean J. Gautier, Columbia University, College of Physicians and Surgeons, USA Short Talk: Regulation of DNA Replication by Myc
Tuesday, March 01 \| 8:00AM - 11:15AM Replication Origins and Replisome Assembly Room: Longs/Grays Peak Speaker 7 of 7 Andrew Jackson, University of Edinburgh, UK Short Talk:
Tuesday, March 01 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Tuesday, March 01 \| 11:15AM - 1:00PM Poster Setup Room: Quandary Peak
Tuesday, March 01 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, March 01 \| 1:00PM - 10:00PM Poster Viewing Room: Quandary Peak
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 1 of 8 * Anja Groth, University of Copenhagen, Denmark New Histone Supply Controls Replication Fork Speed in Human Cells
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 2 of 8 Giuseppe Lia, Centre National de la Recherche Scientifique, France Probing Lagging-Strand Synthesis in Real Time. An in vivo Single Bacteria Study
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 3 of 8 Houra Merrikh, Vanderbilt University, USA Co-Directional Conflicts between Replication and Transcription at rRNA Genes Lead to Replication Fork Stalling and Restart in vivo
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 4 of 8 Nick Rhind, University of Massachusetts Medical School, USA Replication Timing is Regulated by the Number of MCMs Loaded at Origins
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 5 of 8 Christian Speck, MRC-CSC London, UK Stepwise Assembly of a Double-Hexameric MCM2-7 Complex during Licensing of Eukaryotic DNA Replication
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 6 of 8 Philipp Kaldis, Institute of Molecular and Cell Biology, Singapore Cdk1 is Not Required for S Phase Progression but is Essential for Repression of DNA Re-Replication
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 7 of 8 Paulina Hannele Wanrooij, University of Gothenburg, Sweden G-Quadruplex RNA Structures Stimulate Transcription Termination and Priming of Mitochondrial DNA Replication
Tuesday, March 01 \| 2:30PM - 4:30PM Workshop 2: DNA Replication Mechanisms Room: Longs/Grays Peak Speaker 8 of 8 Nicholas E. Dixon, University of Wollongong, Australia A Structural Model of the E. coli Pol III Replicase Complex in the Polymerization Mode
Tuesday, March 01 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Tuesday, March 01 \| 5:00PM - 7:00PM Telomeres and Mitochondria Room: Longs/Grays Peak Speaker 1 of 4 * Titia de Lange, Rockefeller University, USA How Telomeres Solve the End-Protection Problem
Tuesday, March 01 \| 5:00PM - 7:00PM Telomeres and Mitochondria Room: Longs/Grays Peak Speaker 2 of 4 Maria Falkenberg, University of Gothenburg, Sweden Mechanisms of Initiation of DNA Replication in Human Mitochondria
Tuesday, March 01 \| 5:00PM - 7:00PM Telomeres and Mitochondria Room: Longs/Grays Peak Speaker 3 of 4 Bruce Demple, Stony Brook University Medical School, USA Oxidative DNA Damage and Mitochondrial DNA Repair in Cellular Maintenance
Tuesday, March 01 \| 5:00PM - 7:00PM Telomeres and Mitochondria Room: Longs/Grays Peak Speaker 4 of 4 Lisa Hang, Weill Cornell / Memorial Sloan-Kettering Cancer Center, USA Short Talk: SUMO's Influence at the Ends of Chromosomes
Tuesday, March 01 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Quandary Peak
Tuesday, March 01 \| 7:30PM - 10:00PM Poster Session 2 Room: Quandary Peak
Wednesday, March 02 \| 7:00AM - 8:00AM Breakfast Room: Quandary Peak
Wednesday, March 02 \| 8:00AM - 11:15AM Replication Fork Structure Room: Longs/Grays Peak Speaker 1 of 6 * Stephen D. Bell, Indiana University, USA Mechanisms of Archaeal DNA Replication
Wednesday, March 02 \| 8:00AM - 11:15AM Replication Fork Structure Room: Longs/Grays Peak Speaker 2 of 6 Michael E. O'Donnell, Rockefeller University, USA The E. coli Replisome and Use of Clamps to Bypass Replication Barriers
Wednesday, March 02 \| 8:00AM - 11:15AM Replication Fork Structure Room: Longs/Grays Peak Speaker 3 of 6 Hiroyuki Araki, National Institute of Genetics, Japan Short Talk: Essential Function of Pol Epsilon at the Initiation Step of Chromosomal DNA Replication in Budding Yeast
Wednesday, March 02 \| 8:00AM - 11:15AM Replication Fork Structure Room: Longs/Grays Peak Speaker 4 of 6 James M. Berger, Johns Hopkins University School of Medicine, USA Molecular Mechanisms for Initiating DNA Replication
Wednesday, March 02 \| 8:00AM - 11:15AM Replication Fork Structure Room: Longs/Grays Peak Speaker 5 of 6 Antoine M. van Oijen, University of Wollongong, Australia Single-Molecule Studies of the Replisome
Wednesday, March 02 \| 8:00AM - 11:15AM Replication Fork Structure Room: Longs/Grays Peak Speaker 6 of 6 Brian A. Kelch, University of California Berkeley, USA Short Talk: Crystal Structures Provide Snapshots of the Clamp Loading Mechanism
Wednesday, March 02 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Wednesday, March 02 \| 11:15AM - 1:00PM Poster Setup Room: Quandary Peak
Wednesday, March 02 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Wednesday, March 02 \| 1:00PM - 10:00PM Poster Viewing Room: Quandary Peak
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 1 of 8 * Anna Malkova, University of Iowa, USA Break-Induced Replication Is Highly Mutagenic
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 2 of 8 Angela J. Gruber, University of Wisconsin-Madison, USA Role of Escherichia coli RecA in Activation of DNA Polymerase V
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 3 of 8 Gurushankar Chandramouly, Beth Israel Deaconess Medical Center, USA A BRCA1/CtIP-Independent Long Tract Gene Conversion Pathway of Homologous Recombination
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 4 of 8 Kevin Brick, NIDDK, National Institutes of Health, USA Genome-Wide Analysis Reveals Novel Molecular Features of Mouse Recombination Hotspots
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 5 of 8 Ravindra Amunugama, Harvard Medical School, USA RAD51 Turnover is Regulated by the ATP Cap during Homologous Recombinational Repair
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 6 of 8 Thomas Wechsler, Stanford School of Medicine, USA Alternative Pathways of Holliday-Junction Resolution
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 7 of 8 Barnabas Szakal, Istituto FIRC di Oncologia Molecolare, Italy Alternate Pathways Promoting the Resolution of Template Switch Derivatives throughout Cell Cycle
Wednesday, March 02 \| 2:30PM - 4:30PM Workshop 3: DNA Recombination Mechanisms Room: Longs/Grays Peak Speaker 8 of 8 Sandeep Burma, University of Texas Southwestern Medical Center, USA DNA Resection by Exo1 Dictates Critical DNA Repair and Damage Signaling Decisions in Response to DNA Double-Strand Breaks
Wednesday, March 02 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Wednesday, March 02 \| 5:00PM - 7:00PM Recombination and DNA Repair Room: Longs/Grays Peak Speaker 1 of 4 * James E. Haber, Brandeis University, USA Control of Gene Conversion and Break-Induced Replication
Wednesday, March 02 \| 5:00PM - 7:00PM Recombination and DNA Repair Room: Longs/Grays Peak Speaker 2 of 4 Akira Shinohara, Osaka University, Japan The Psy3-Csm2-Shu1-Shu2 (PCSS) Complex, a New Rad51 Mediator, in Homologous Recombination
Wednesday, March 02 \| 5:00PM - 7:00PM Recombination and DNA Repair Room: Longs/Grays Peak Speaker 3 of 4 Catherine H. Freudenreich, Tufts University, USA Trinucleotide Repeat Instability: Links to Replication and Recombination
Wednesday, March 02 \| 5:00PM - 7:00PM Recombination and DNA Repair Room: Longs/Grays Peak Speaker 4 of 4 Katharina Schlacher, MD Anderson Cancer Center, USA Short Talk: Homologous Recombination Independent Role For BRCA2 In Blocking Stalled Replication Fork Degradation By MRE11
Wednesday, March 02 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Quandary Peak
Wednesday, March 02 \| 7:30PM - 10:00PM Poster Session 3 Room: Quandary Peak
Thursday, March 03 \| 7:00AM - 8:00AM Breakfast Room: Quandary Peak
Thursday, March 03 \| 8:00AM - 11:15AM Alterations in DNA and Chromatin Room: Longs/Grays Peak Speaker 1 of 6 * Patrick M. Sung, University of Texas Health Science Center at San Antonio, USA Mechanism and Regulation of the Helicase-Driven Path of DNA End Resection in Saccharomyces cerevisiae
Thursday, March 03 \| 8:00AM - 11:15AM Alterations in DNA and Chromatin Room: Longs/Grays Peak Speaker 2 of 6 Geneviève Almouzni, Centre National de la Recherche Scientifique, France Variation on the Theme of Chromatin Assembly
Thursday, March 03 \| 8:00AM - 11:15AM Alterations in DNA and Chromatin Room: Longs/Grays Peak Speaker 3 of 6 Michael M. Cox, University of Wisconsin-Madison, USA Short Talk: Oligonucleotide-Directed DNA Cleavage with a Novel RecA-Dependent Nuclease
Thursday, March 03 \| 8:00AM - 11:15AM Alterations in DNA and Chromatin Room: Longs/Grays Peak Speaker 4 of 6 Taekjip Ha, Johns Hopkins University, USA Single Molecule Fluorescence-Force Analysis of Protein Dynamics on Single Stranded DNA
Thursday, March 03 \| 8:00AM - 11:15AM Alterations in DNA and Chromatin Room: Longs/Grays Peak Speaker 5 of 6 Ian D. Hickson, University of Copenhagen, Denmark Roles of BLM in Recombination and Replication
Thursday, March 03 \| 8:00AM - 11:15AM Alterations in DNA and Chromatin Room: Longs/Grays Peak Speaker 6 of 6 Mara G. Prentiss, Harvard University, USA Short Talk: Mechanical Stress is a Stringency Factor for RecA-Mediated Homology Searching
Thursday, March 03 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Thursday, March 03 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 1 of 8 * Francesca Storici, Georgia Institute of Technology, USA Resolution of RNA/DNA Mispairs Results from Interplay between Mismatch Repair and RNase H Functions
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 2 of 8 David Thomas Long, Medical University of South Carolina, USA Homology-Directed DNA Interstrand Cross-Link Repair in S Phase
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 3 of 8 Arnab Ray Chaudhuri, Erasmus University Medical Center, Netherlands Replication Fork Regression Precedes Double Strand Break Formation Upon Topoisomerase I Inhibition
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 4 of 8 Mitch McVey, Tufts University, USA The Bloom Syndrome Helicase Prevents Spontaneous Genome Rearrangements and Tumorigenesis during Aging in Drosophila
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 5 of 8 Grant W. Brown, University of Toronto, Canada Genomic Instability Results in an Unscheduled Expansion of dNTP Pools
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 6 of 8 Vincent Dion, University of Lausanne, Switzerland Live Imaging of Chromatin Mobility during DNA Repair
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 7 of 8 M. Todd Washington, University of Iowa, USA Crystal Structures of Ubiquitin-Modified and SUMO-Modified PCNA
Thursday, March 03 \| 2:30PM - 4:30PM Workshop 4: DNA Damage Response Mechanisms Room: Longs/Grays Peak Speaker 8 of 8 Kirill S. Lobachev, Georgia Institute of Technology, USA The Role of Structure-Specific Nucleases and Helicases in Cell Cycle Regulated Palindrome Fragility in Yeast
Thursday, March 03 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Thursday, March 03 \| 5:00PM - 7:00PM DNA Damage Response Room: Longs/Grays Peak Speaker 1 of 4 * Helle D. Ulrich, Institute of Molecular Biology, Germany Timing and Spacing of Ubiquitin-Dependent DNA Damage Bypass
Thursday, March 03 \| 5:00PM - 7:00PM DNA Damage Response Room: Longs/Grays Peak Speaker 2 of 4 Peter M. Burgers, Washington University School of Medicine, USA Metal Binding Clusters in Eukaryotic B-Family DNA Polymerases Mediate Subunit Interactions and Replication Processivity
Thursday, March 03 \| 5:00PM - 7:00PM DNA Damage Response Room: Longs/Grays Peak Speaker 3 of 4 Lee Zou, Harvard Medical School, USA New Insights into the Mechanisms of ATR Activation in Human Cells
Thursday, March 03 \| 5:00PM - 7:00PM DNA Damage Response Room: Longs/Grays Peak Speaker 4 of 4 Anindya Dutta, University of Virginia, USA Short Talk: The Effect of the Intra-S-Phase Checkpoint on Origins of Replication in Human Cells
Thursday, March 03 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Quandary Peak
Thursday, March 03 \| 8:00PM - 11:00PM Entertainment Room: Quandary Peak
Thursday, March 03 \| 8:00PM - 11:00PM Cash Bar Room: Quandary Peak
Friday, March 04 \| 10:25AM - 10:25AM Departure *Session Chair.