Web Desc
DNA Replication and Recombination
Organizer(s): Peter M. Burgers, Lorraine S. Symington and Johannes Walter
Date: February 27 - March 04, 2011
Location: Keystone Resort, Keystone, CO, USA
Supported by the Directors' Fund
Summary of Meeting:
As the pathways that govern DNA replication and DNA recombination are better defined, there is exciting progress in our understanding of the basic mechanisms of these processes. There is also growing evidence that replication and recombination are intimately connected in order to resolve problems arising during DNA replication, and to define outcomes with respect to chromosome integrity. This meeting will integrate mechanistic insights from biochemical studies with cellular pathways that control DNA replication initiation and progression, DNA recombination, and responses to DNA damage. Specific plenary sessions will focus on DNA replication mechanisms in prokaryotes and eukaryotes. Recombination sessions will present progress in our understanding of the mechanisms underlying mitotic recombination, and on recombination-based responses to replication stress and DNA damage. Sessions will also address cell cycle checkpoint and chromatin structural responses to DNA damage. The plenary sessions will be conducted by invited speakers and speakers selected from submitted abstracts. In addition, four related workshops will be conducted, with short talks selected from submitted abstracts.
Scholarship Deadline: October 27 2010
Discounted Abstract Deadline: October 27 2010
Abstract Deadline: November 30 2010
Discounted Registration Deadline: December 29 2010
We gratefully acknowledge additional support for this conference from:
Integrated DNA Technologies


Francesca Storici
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, February 27 | 3:00PM - 7:30PM
Registration
Room: Longs Peak Foyer


Sunday, February 27 | 6:15PM - 7:15PM
Refreshments
Room: Longs Peak Foyer


Sunday, February 27 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Longs/Grays Peak

Speaker 1 of 1
Stephen C. Kowalczykowski, University of California, Davis, USA
Mechanics and Visualization of Recombinational DNA Repair

Monday, February 28 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Monday, February 28 | 8:00AM - 11:15AM
Replication Fidelity and Mutagenesis
Room: Longs/Grays Peak

Speaker 1 of 6
* Thomas A. Kunkel, NIEHS, National Institutes of Health, USA
Generating and Correcting Leading- and Lagging-Strand DNA Replication Errors

Monday, February 28 | 8:00AM - 11:15AM
Replication Fidelity and Mutagenesis
Room: Longs/Grays Peak

Speaker 2 of 6
Peggy Hsieh, NIDDK, National Institutes of Health, USA
DNA Mismatch Excision Repair and Damage Signaling

Monday, February 28 | 8:00AM - 11:15AM
Replication Fidelity and Mutagenesis
Room: Longs/Grays Peak

Speaker 3 of 6
Erik Johansson, Umeå University, Sweden
Short Talk: Mismatch Repair-Independent Increase in Spontaneous Mutagenesis in Yeast Lacking Non-Essential Subunits of Pol epsilon

Monday, February 28 | 8:00AM - 11:15AM
Replication Fidelity and Mutagenesis
Room: Longs/Grays Peak

Speaker 4 of 6
Karen M. Vasquez, University of Texas, Austin, USA
DNA Structure and Mutagenesis

Monday, February 28 | 8:00AM - 11:15AM
Replication Fidelity and Mutagenesis
Room: Longs/Grays Peak

Speaker 5 of 6
Susan T. Lovett, Brandeis University, USA
A Template-Switch Mechanism for Muational Hotspots

Monday, February 28 | 8:00AM - 11:15AM
Replication Fidelity and Mutagenesis
Room: Longs/Grays Peak

Speaker 6 of 6
Andrei Chabes, Umeå University, Sweden
Short Talk: Mechanisms of Mutagenesis in vivo Due to Imbalanced dNTP Pools

Monday, February 28 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Monday, February 28 | 11:15AM - 1:00PM
Poster Setup
Room: Quandary Peak


Monday, February 28 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Monday, February 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary Peak


Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 1 of 8
Roxana Georgescu, Rockefeller University, USA
Filling the Gaps … at the Replication Fork

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 2 of 8
Christopher D. Downey, University of Colorado, Boulder, USA
Chaperoning of a Replicative Polymerase by its Clamp Loader Plays an Integral Role in Initiation Complex Formation

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 3 of 8
Aimee H. Marceau, University of Wisconsin-Madison, USA
Structural Identification of the E. coli SSB Binding Site on the Chi/Psi Subassembly of the Clamp-Loader Complex

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 4 of 8
* Sergey Korolev, St. Louis University Medical School, USA
RecOR Alter Conformation of SSB-Bound ssDNA

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 5 of 8
Jeehae Park, University of Illinois at Urbana Champaign, USA
Reeling in DNA One Nucleotide at a Time: Repetitive Looping Coupled with PcrA Translocation Dismantles RecA Filaments

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 6 of 8
Richard U. Rymer, University of California Berkeley, USA
The Structural Basis for Nucleotide Binding by Bacterial Primase

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 7 of 8
Susan E. Tsutakawa, Lawrence Berkeley National Laboratory, USA
Recognition of 5’ Flaps by Flap Endonuclease, hFEN1

Monday, February 28 | 2:30PM - 4:30PM
Workshop 1: Nucleic Acid Enzymes
Room: Longs/Grays Peak

Speaker 8 of 8
Lorena S. Beese, Duke University Medical Center, USA
Human Exonuclease I Complexes with DNA: Implications for the Nucleolytic Step in DNA Repair

Monday, February 28 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, February 28 | 5:00PM - 7:00PM
Homologous Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 1 of 4
* Wolf-Dietrich Heyer, University of California, Davis, USA
Formation and Disassembly of the Rad51-ssDNA Filament is Controlled by a Balance of the Rad51 Paralogs Rad55-Rad57 and the Anti-Recombinase Srs2

Monday, February 28 | 5:00PM - 7:00PM
Homologous Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 2 of 4
Lorraine S. Symington, Columbia University, USA
The Mus81-Mms4 and Yen1 Nucleases Promote Reciprocal Exchange during Mitotic Recombination

Monday, February 28 | 5:00PM - 7:00PM
Homologous Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 3 of 4
Cees Dekker, Delft University of Technology, Netherlands
Single Molecule Studies of Recombinase Proteins

Monday, February 28 | 5:00PM - 7:00PM
Homologous Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 4 of 4
Ilya J. Finkelstein, University of Texas at Austin, USA
Short Talk: Single-Molecule Imaging Reveals Mechanisms of how RecBCD Strips DNA-Bound Obstacles

Monday, February 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Monday, February 28 | 7:30PM - 10:00PM
Poster Session 1
Room: Quandary Peak


Tuesday, March 01 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 1 of 7
* John F.X. Diffley, Francis Crick Institute, UK
Early Events in Eukaryotic DNA Replication

Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 2 of 7
Johannes C. Walter, Harvard Medical School, USA
Mechanism of the MCM2-7 DNA Helicase

Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 3 of 7
Stephen P. Bell, Massachusetts Institute of Technology, USA
Short Talk: S. Cerevisiae Origin-Dependent Replication Initiation in vitro: Insights into Kinase Function and Polymerase Loading

Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 4 of 7
Michael Botchan, University of California, Berkeley, USA
Regulation and Activation of the MCM Helicase

Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 5 of 7
Bruce W. Stillman, Cold Spring Harbor Laboratory, USA
Multiple Activities For The Origin Recognition Complex (ORC) During The Chromosome Duplication And Segregation Cycle

Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 6 of 7
Jean J. Gautier, Columbia University, College of Physicians and Surgeons, USA
Short Talk: Regulation of DNA Replication by Myc

Tuesday, March 01 | 8:00AM - 11:15AM
Replication Origins and Replisome Assembly
Room: Longs/Grays Peak

Speaker 7 of 7
Andrew Jackson, University of Edinburgh, UK
Short Talk:

Tuesday, March 01 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 01 | 11:15AM - 1:00PM
Poster Setup
Room: Quandary Peak


Tuesday, March 01 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Tuesday, March 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary Peak


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 1 of 8
* Anja Groth, University of Copenhagen, Denmark
New Histone Supply Controls Replication Fork Speed in Human Cells

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 2 of 8
Giuseppe Lia, Centre National de la Recherche Scientifique, France
Probing Lagging-Strand Synthesis in Real Time. An in vivo Single Bacteria Study

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 3 of 8
Houra Merrikh, Vanderbilt University, USA
Co-Directional Conflicts between Replication and Transcription at rRNA Genes Lead to Replication Fork Stalling and Restart in vivo

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 4 of 8
Nick Rhind, University of Massachusetts Medical School, USA
Replication Timing is Regulated by the Number of MCMs Loaded at Origins

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 5 of 8
Christian Speck, MRC-CSC London, UK
Stepwise Assembly of a Double-Hexameric MCM2-7 Complex during Licensing of Eukaryotic DNA Replication

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 6 of 8
Philipp Kaldis, Institute of Molecular and Cell Biology, Singapore
Cdk1 is Not Required for S Phase Progression but is Essential for Repression of DNA Re-Replication

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 7 of 8
Paulina Hannele Wanrooij, University of Gothenburg, Sweden
G-Quadruplex RNA Structures Stimulate Transcription Termination and Priming of Mitochondrial DNA Replication

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 2: DNA Replication Mechanisms
Room: Longs/Grays Peak

Speaker 8 of 8
Nicholas E. Dixon, University of Wollongong, Australia
A Structural Model of the E. coli Pol III Replicase Complex in the Polymerization Mode

Tuesday, March 01 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 01 | 5:00PM - 7:00PM
Telomeres and Mitochondria
Room: Longs/Grays Peak

Speaker 1 of 4
* Titia de Lange, Rockefeller University, USA
How Telomeres Solve the End-Protection Problem

Tuesday, March 01 | 5:00PM - 7:00PM
Telomeres and Mitochondria
Room: Longs/Grays Peak

Speaker 2 of 4
Maria Falkenberg, University of Gothenburg, Sweden
Mechanisms of Initiation of DNA Replication in Human Mitochondria

Tuesday, March 01 | 5:00PM - 7:00PM
Telomeres and Mitochondria
Room: Longs/Grays Peak

Speaker 3 of 4
Bruce Demple, Stony Brook University Medical School, USA
Oxidative DNA Damage and Mitochondrial DNA Repair in Cellular Maintenance

Tuesday, March 01 | 5:00PM - 7:00PM
Telomeres and Mitochondria
Room: Longs/Grays Peak

Speaker 4 of 4
Lisa Hang, Weill Cornell / Memorial Sloan-Kettering Cancer Center, USA
Short Talk: SUMO's Influence at the Ends of Chromosomes

Tuesday, March 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Tuesday, March 01 | 7:30PM - 10:00PM
Poster Session 2
Room: Quandary Peak


Wednesday, March 02 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Wednesday, March 02 | 8:00AM - 11:15AM
Replication Fork Structure
Room: Longs/Grays Peak

Speaker 1 of 6
* Stephen D. Bell, Indiana University, USA
Mechanisms of Archaeal DNA Replication

Wednesday, March 02 | 8:00AM - 11:15AM
Replication Fork Structure
Room: Longs/Grays Peak

Speaker 2 of 6
Michael E. O'Donnell, Rockefeller University, USA
The E. coli Replisome and Use of Clamps to Bypass Replication Barriers

Wednesday, March 02 | 8:00AM - 11:15AM
Replication Fork Structure
Room: Longs/Grays Peak

Speaker 3 of 6
Hiroyuki Araki, National Institute of Genetics, Japan
Short Talk: Essential Function of Pol Epsilon at the Initiation Step of Chromosomal DNA Replication in Budding Yeast

Wednesday, March 02 | 8:00AM - 11:15AM
Replication Fork Structure
Room: Longs/Grays Peak

Speaker 4 of 6
James M. Berger, Johns Hopkins University School of Medicine, USA
Molecular Mechanisms for Initiating DNA Replication

Wednesday, March 02 | 8:00AM - 11:15AM
Replication Fork Structure
Room: Longs/Grays Peak

Speaker 5 of 6
Antoine M. van Oijen, University of Wollongong, Australia
Single-Molecule Studies of the Replisome

Wednesday, March 02 | 8:00AM - 11:15AM
Replication Fork Structure
Room: Longs/Grays Peak

Speaker 6 of 6
Brian A. Kelch, University of California Berkeley, USA
Short Talk: Crystal Structures Provide Snapshots of the Clamp Loading Mechanism

Wednesday, March 02 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, March 02 | 11:15AM - 1:00PM
Poster Setup
Room: Quandary Peak


Wednesday, March 02 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Wednesday, March 02 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary Peak


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 1 of 8
* Anna Malkova, University of Iowa, USA
Break-Induced Replication Is Highly Mutagenic

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 2 of 8
Angela J. Gruber, University of Wisconsin-Madison, USA
Role of Escherichia coli RecA in Activation of DNA Polymerase V

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 3 of 8
Gurushankar Chandramouly, Beth Israel Deaconess Medical Center, USA
A BRCA1/CtIP-Independent Long Tract Gene Conversion Pathway of Homologous Recombination

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 4 of 8
Kevin Brick, NIDDK, National Institutes of Health, USA
Genome-Wide Analysis Reveals Novel Molecular Features of Mouse Recombination Hotspots

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 5 of 8
Ravindra Amunugama, Harvard Medical School, USA
RAD51 Turnover is Regulated by the ATP Cap during Homologous Recombinational Repair

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 6 of 8
Thomas Wechsler, Stanford School of Medicine, USA
Alternative Pathways of Holliday-Junction Resolution

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 7 of 8
Barnabas Szakal, Istituto FIRC di Oncologia Molecolare, Italy
Alternate Pathways Promoting the Resolution of Template Switch Derivatives throughout Cell Cycle

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 3: DNA Recombination Mechanisms
Room: Longs/Grays Peak

Speaker 8 of 8
Sandeep Burma, University of Texas Southwestern Medical Center, USA
DNA Resection by Exo1 Dictates Critical DNA Repair and Damage Signaling Decisions in Response to DNA Double-Strand Breaks

Wednesday, March 02 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, March 02 | 5:00PM - 7:00PM
Recombination and DNA Repair
Room: Longs/Grays Peak

Speaker 1 of 4
* James E. Haber, Brandeis University, USA
Control of Gene Conversion and Break-Induced Replication

Wednesday, March 02 | 5:00PM - 7:00PM
Recombination and DNA Repair
Room: Longs/Grays Peak

Speaker 2 of 4
Akira Shinohara, Osaka University, Japan
The Psy3-Csm2-Shu1-Shu2 (PCSS) Complex, a New Rad51 Mediator, in Homologous Recombination

Wednesday, March 02 | 5:00PM - 7:00PM
Recombination and DNA Repair
Room: Longs/Grays Peak

Speaker 3 of 4
Catherine H. Freudenreich, Tufts University, USA
Trinucleotide Repeat Instability: Links to Replication and Recombination

Wednesday, March 02 | 5:00PM - 7:00PM
Recombination and DNA Repair
Room: Longs/Grays Peak

Speaker 4 of 4
Katharina Schlacher, MD Anderson Cancer Center, USA
Short Talk: Homologous Recombination Independent Role For BRCA2 In Blocking Stalled Replication Fork Degradation By MRE11

Wednesday, March 02 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Wednesday, March 02 | 7:30PM - 10:00PM
Poster Session 3
Room: Quandary Peak


Thursday, March 03 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Thursday, March 03 | 8:00AM - 11:15AM
Alterations in DNA and Chromatin
Room: Longs/Grays Peak

Speaker 1 of 6
* Patrick M. Sung, University of Texas Health Science Center at San Antonio, USA
Mechanism and Regulation of the Helicase-Driven Path of DNA End Resection in Saccharomyces cerevisiae


Thursday, March 03 | 8:00AM - 11:15AM
Alterations in DNA and Chromatin
Room: Longs/Grays Peak

Speaker 2 of 6
Geneviève Almouzni, Centre National de la Recherche Scientifique, France
Variation on the Theme of Chromatin Assembly

Thursday, March 03 | 8:00AM - 11:15AM
Alterations in DNA and Chromatin
Room: Longs/Grays Peak

Speaker 3 of 6
Michael M. Cox, University of Wisconsin-Madison, USA
Short Talk: Oligonucleotide-Directed DNA Cleavage with a Novel RecA-Dependent Nuclease

Thursday, March 03 | 8:00AM - 11:15AM
Alterations in DNA and Chromatin
Room: Longs/Grays Peak

Speaker 4 of 6
Taekjip Ha, Johns Hopkins University, USA
Single Molecule Fluorescence-Force Analysis of Protein Dynamics on Single Stranded DNA

Thursday, March 03 | 8:00AM - 11:15AM
Alterations in DNA and Chromatin
Room: Longs/Grays Peak

Speaker 5 of 6
Ian D. Hickson, University of Copenhagen, Denmark
Roles of BLM in Recombination and Replication

Thursday, March 03 | 8:00AM - 11:15AM
Alterations in DNA and Chromatin
Room: Longs/Grays Peak

Speaker 6 of 6
Mara G. Prentiss, Harvard University, USA
Short Talk: Mechanical Stress is a Stringency Factor for RecA-Mediated Homology Searching

Thursday, March 03 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, March 03 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 1 of 8
* Francesca Storici, Georgia Institute of Technology, USA
Resolution of RNA/DNA Mispairs Results from Interplay between Mismatch Repair and RNase H Functions

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 2 of 8
David Thomas Long, Medical University of South Carolina, USA
Homology-Directed DNA Interstrand Cross-Link Repair in S Phase

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 3 of 8
Arnab Ray Chaudhuri, Erasmus University Medical Center, Netherlands
Replication Fork Regression Precedes Double Strand Break Formation Upon Topoisomerase I Inhibition

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 4 of 8
Mitch McVey, Tufts University, USA
The Bloom Syndrome Helicase Prevents Spontaneous Genome Rearrangements and Tumorigenesis during Aging in Drosophila

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 5 of 8
Grant W. Brown, University of Toronto, Canada
Genomic Instability Results in an Unscheduled Expansion of dNTP Pools

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 6 of 8
Vincent Dion, University of Lausanne, Switzerland
Live Imaging of Chromatin Mobility during DNA Repair

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 7 of 8
M. Todd Washington, University of Iowa, USA
Crystal Structures of Ubiquitin-Modified and SUMO-Modified PCNA

Thursday, March 03 | 2:30PM - 4:30PM
Workshop 4: DNA Damage Response Mechanisms
Room: Longs/Grays Peak

Speaker 8 of 8
Kirill S. Lobachev, Georgia Institute of Technology, USA
The Role of Structure-Specific Nucleases and Helicases in Cell Cycle Regulated Palindrome Fragility in Yeast

Thursday, March 03 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, March 03 | 5:00PM - 7:00PM
DNA Damage Response
Room: Longs/Grays Peak

Speaker 1 of 4
* Helle D. Ulrich, Institute of Molecular Biology, Germany
Timing and Spacing of Ubiquitin-Dependent DNA Damage Bypass

Thursday, March 03 | 5:00PM - 7:00PM
DNA Damage Response
Room: Longs/Grays Peak

Speaker 2 of 4
Peter M. Burgers, Washington University School of Medicine, USA
Metal Binding Clusters in Eukaryotic B-Family DNA Polymerases Mediate Subunit Interactions and Replication Processivity

Thursday, March 03 | 5:00PM - 7:00PM
DNA Damage Response
Room: Longs/Grays Peak

Speaker 3 of 4
Lee Zou, Harvard Medical School, USA
New Insights into the Mechanisms of ATR Activation in Human Cells

Thursday, March 03 | 5:00PM - 7:00PM
DNA Damage Response
Room: Longs/Grays Peak

Speaker 4 of 4
Anindya Dutta, University of Virginia, USA
Short Talk: The Effect of the Intra-S-Phase Checkpoint on Origins of Replication in Human Cells

Thursday, March 03 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Thursday, March 03 | 8:00PM - 11:00PM
Entertainment
Room: Quandary Peak


Thursday, March 03 | 8:00PM - 11:00PM
Cash Bar
Room: Quandary Peak


Friday, March 04 | 10:25AM - 10:25AM
Departure


*Session Chair.