Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
There are no records.

Web Desc
New Frontiers at the Interface of Immunity and Glycobiology Organizer(s): Brian A. Cobb, Gabriel A. Rabinovich and Yvette van Kooyk Date: March 06 - 11, 2011 Location: Fairmont Chateau Lake Louise, Lake Louise, AB, Canada Supported by the Directors' Fund Summary of Meeting: Carbohydrates are often overlooked in the study of the immune system, yet mounting data show that glycans, whether microbial or host in origin, play central roles in essentially all immune response pathways. Changes in glycosylation of host proteins can lead to autoimmunity, indicate oncogenic transformation, or even promote metastasis. Inflammation can be strongly influenced by carbohydrate binding proteins on immune cells. Selectins play critical roles in cell homing to the site of infection, while glycosylation directly influences cellular development and differentiation. Recent advances also highlight how glycan-mediated antigen recognition by dendritic cells impacts our understanding of the innate immune response, while other findings reveal that glycolipids and bacterial polysaccharides can lead to NKT and T cell activation. The goal of this meeting is to bring together the international “glycoimmunology” community to foster interactions and promote the latest insights into the role of glycans in the immune system. Scholarship Deadline: November 15 2010 Discounted Abstract Deadline: November 15 2010 Abstract Deadline: December 9 2010 Discounted Registration Deadline: January 6 2011 We gratefully acknowledge additional support for this conference from: Genentech, Inc. We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Genentech, Inc. We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI094888-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

New Frontiers at the Interface of Immunity and Glycobiology

Organizer(s): Brian A. Cobb, Gabriel A. Rabinovich and Yvette van Kooyk

Date: March 06 - 11, 2011
Location: Fairmont Chateau Lake Louise, Lake Louise, AB, Canada

Supported by the Directors' Fund

Summary of Meeting:

Carbohydrates are often overlooked in the study of the immune system, yet mounting data show that glycans, whether microbial or host in origin, play central roles in essentially all immune response pathways. Changes in glycosylation of host proteins can lead to autoimmunity, indicate oncogenic transformation, or even promote metastasis. Inflammation can be strongly influenced by carbohydrate binding proteins on immune cells. Selectins play critical roles in cell homing to the site of infection, while glycosylation directly influences cellular development and differentiation. Recent advances also highlight how glycan-mediated antigen recognition by dendritic cells impacts our understanding of the innate immune response, while other findings reveal that glycolipids and bacterial polysaccharides can lead to NKT and T cell activation. The goal of this meeting is to bring together the international “glycoimmunology” community to foster interactions and promote the latest insights into the role of glycans in the immune system.

Scholarship Deadline: November 15 2010

Discounted Abstract Deadline: November 15 2010

Abstract Deadline: December 9 2010

Discounted Registration Deadline: January 6 2011

We gratefully acknowledge additional support for this conference from:

Genentech, Inc.

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI094888-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 06 \| 3:00PM - 7:30PM Registration Room: Alpine Gallery
Sunday, March 06 \| 6:15PM - 7:15PM Refreshments Room: Heritage Hall
Sunday, March 06 \| 7:15PM - 8:30PM Welcome and Keynote Address Room: Mt Temple A/B Speaker 1 of 1 James C. Paulson, The Scripps Research Institute, USA Modulating Innate and Adaptive Immune Responses with Glycan Ligands of Siglecs
Monday, March 07 \| 7:00AM - 8:00AM Breakfast Room: Tom Wilson Dining Room
Monday, March 07 \| 8:00AM - 11:15AM B and T Cell Responses and Recognition Room: Mt Temple A/B Speaker 1 of 6 * Brian A. Cobb, Case Western Reserve University School of Medicine, USA MHCII-Mediated T cell Activation by Bacterial Carbohydrate Antigens
Monday, March 07 \| 8:00AM - 11:15AM B and T Cell Responses and Recognition Room: Mt Temple A/B Speaker 2 of 6 Michael B. Brenner, Harvard Medical School, USA Glycan-Driven Innate Mechanisms Activate CD1d Restricted iNKT Cell Responses to Fungi and Other Microbes
Monday, March 07 \| 8:00AM - 11:15AM B and T Cell Responses and Recognition Room: Mt Temple A/B Speaker 3 of 6 Mitchell Kronenberg, La Jolla Institute for Allergy and Immunology, USA Recognition of Glycolipids from Pathogenic Microbes by Natural Killer T Cells
Monday, March 07 \| 8:00AM - 11:15AM B and T Cell Responses and Recognition Room: Mt Temple A/B Speaker 4 of 6 Linda G. Baum, University of California, Los Angeles, USA CD45 and CD43 Glycosylation during T Cell Maturation, Activation and Survival
Monday, March 07 \| 8:00AM - 11:15AM B and T Cell Responses and Recognition Room: Mt Temple A/B Speaker 5 of 6 María Belén Prados, Universidad Nacional de Río Negro, Argentina Short Talk: Progesterone Induces a Switch in Oligosaccharyltransferase Isoform Expression: Consequences on IgG N-Glycosylation
Monday, March 07 \| 8:00AM - 11:15AM B and T Cell Responses and Recognition Room: Mt Temple A/B Speaker 6 of 6 Nina Salinger, Emory University School of Medicine, USA Short Talk: Anti-Glycan Responses in Mice to Glycan Antigens from the Parasitic Trematode Schistosoma mansoni
Monday, March 07 \| 9:20AM - 9:40AM Coffee Break Room: Heritage Hall
Monday, March 07 \| 11:15AM - 1:00PM Poster Setup Room: Mt Temple C
Monday, March 07 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Monday, March 07 \| 1:00PM - 10:00PM Poster Viewing Room: Mt Temple C
Monday, March 07 \| 4:30PM - 5:00PM Coffee Available Room: Heritage Hall
Monday, March 07 \| 5:00PM - 7:00PM Innate Immune Responses and Recognition Room: Mt Temple A/B Speaker 1 of 4 * Paul R. Crocker, University of Dundee, UK CD33-Related Siglecs in Modulation of Inflammatory Responses
Monday, March 07 \| 5:00PM - 7:00PM Innate Immune Responses and Recognition Room: Mt Temple A/B Speaker 2 of 4 Jamey D. Marth, Sanford-Burnham Medical Research Institute, USA Exposure and Sensing of Dangerous Glycans in the Prevention and Pathogenesis of Disease
Monday, March 07 \| 5:00PM - 7:00PM Innate Immune Responses and Recognition Room: Mt Temple A/B Speaker 3 of 4 Caetano Reis e Sousa, Francis Crick Institute, UK Syk-Coupled C-Type Lectins at the Crossroads of Innate and Adaptive Immunity
Monday, March 07 \| 5:00PM - 7:00PM Innate Immune Responses and Recognition Room: Mt Temple A/B Speaker 4 of 4 Smanla Tundup, University of Georgia, USA Short Talk: Immune Regulation in Response to Schistosoma Antigen
Monday, March 07 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Mt Temple C
Monday, March 07 \| 7:30PM - 10:00PM Poster Session 1 Room: Mt Temple C
Tuesday, March 08 \| 7:00AM - 8:00AM Breakfast Room: Tom Wilson Dining Room
Tuesday, March 08 \| 8:00AM - 11:15AM Cell Communication, Homing and Inflammation Room: Mt Temple A/B Speaker 1 of 6 * Yvette van Kooyk, Vrije University Medical Center, Netherlands Carbohydrate Recognition by Dendritic Cells and Cell Communication
Tuesday, March 08 \| 8:00AM - 11:15AM Cell Communication, Homing and Inflammation Room: Mt Temple A/B Speaker 2 of 6 Rodger P. McEver, Oklahoma Medical Research Foundation, USA Selectin-Glycoconjugate Interactions in Cell Communication
Tuesday, March 08 \| 8:00AM - 11:15AM Cell Communication, Homing and Inflammation Room: Mt Temple A/B Speaker 3 of 6 Sachiko Sato, Laval University, Canada Cytosolic Lectin, Galectin-3 and Innate Immune Response during Infections
Tuesday, March 08 \| 8:00AM - 11:15AM Cell Communication, Homing and Inflammation Room: Mt Temple A/B Speaker 4 of 6 Fu-Tong Liu, Academia Sinica, Taiwan Galectins in Allergic Inflammation
Tuesday, March 08 \| 8:00AM - 11:15AM Cell Communication, Homing and Inflammation Room: Mt Temple A/B Speaker 5 of 6 Hiroto Kawashima, University of Shizuoka, Japan Short Talk: Essential Role of Peripheral Node Addressin in Lymphocyte Homing to Nasal-Associated Lymphoid Tissues and Allergic Immune Responses
Tuesday, March 08 \| 8:00AM - 11:15AM Cell Communication, Homing and Inflammation Room: Mt Temple A/B Speaker 6 of 6 Jeffrey C. Nolz, University of Iowa, USA Short Talk: Memory CD8 Tcell Recruitment through Regulation of Selectin Ligand
Tuesday, March 08 \| 9:20AM - 9:40AM Coffee Break Room: Heritage Hall
Tuesday, March 08 \| 11:15AM - 1:00PM Poster Setup Room: Mt Temple C
Tuesday, March 08 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, March 08 \| 1:00PM - 10:00PM Poster Viewing Room: Mt Temple C
Tuesday, March 08 \| 4:30PM - 5:00PM Coffee Available Room: Heritage Hall
Tuesday, March 08 \| 5:00PM - 7:00PM Workshop and Panel: High-Throughput Screening in Glycomics o f the Immune Response Room: Mt Temple A/B This workshop and panel will discuss new technologies and techniques to study glycobiology at the 'glycomic' scale. After the invited talks, the audience will join in a roundtable interactive session designed to promote glycomics to understand the immune response and to foster potential collaborations. Speaker 1 of 3 * Anne Dell, Imperial College London, UK High Sensitivity Mass Spectrometric Analysis of Glycosylation Patterns
Tuesday, March 08 \| 5:00PM - 7:00PM Workshop and Panel: High-Throughput Screening in Glycomics o f the Immune Response Room: Mt Temple A/B This workshop and panel will discuss new technologies and techniques to study glycobiology at the 'glycomic' scale. After the invited talks, the audience will join in a roundtable interactive session designed to promote glycomics to understand the immune response and to foster potential collaborations. Speaker 2 of 3 Michael Pierce, CCRC, USA Application of Glycomic Technologies to Identify Potential Cellular Markers and Investigate Glycan Function
Tuesday, March 08 \| 5:00PM - 7:00PM Workshop and Panel: High-Throughput Screening in Glycomics o f the Immune Response Room: Mt Temple A/B This workshop and panel will discuss new technologies and techniques to study glycobiology at the 'glycomic' scale. After the invited talks, the audience will join in a roundtable interactive session designed to promote glycomics to understand the immune response and to foster potential collaborations. Speaker 3 of 3 Ten Feizi, Imperial College London, UK Ligand Discovery for Carbohydrate Recognition Systems
Tuesday, March 08 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Mt Temple C
Tuesday, March 08 \| 7:30PM - 10:00PM Poster Session 2 Room: Mt Temple C
Wednesday, March 09 \| 7:00AM - 8:00AM Breakfast Room: Tom Wilson Dining Room
Wednesday, March 09 \| 8:00AM - 11:15AM Host-Pathogen Interactions Room: Mt Temple A/B Speaker 1 of 6 * Richard Cummings, Emory University, USA O- and N-Glycosylation Pathways in Host-Pathogen Interactions
Wednesday, March 09 \| 8:00AM - 11:15AM Host-Pathogen Interactions Room: Mt Temple A/B Speaker 2 of 6 Stephen M. Beverley, Washington University School of Medicine, USA The Role of Glycoconjugates in Infectivity and Immune Reponses Against the Protozoan Parasite Leishmania major
Wednesday, March 09 \| 8:00AM - 11:15AM Host-Pathogen Interactions Room: Mt Temple A/B Speaker 3 of 6 Gerardo R. Vasta, University of Maryland School of Medicine, USA C- and F-Type Lectins, and Galectins in Host-Pathogen Interactions
Wednesday, March 09 \| 8:00AM - 11:15AM Host-Pathogen Interactions Room: Mt Temple A/B Speaker 4 of 6 Teunis B.H. Geijtenbeek, University of Amsterdam, Netherlands C-type lectin signaling in immunity and infection
Wednesday, March 09 \| 8:00AM - 11:15AM Host-Pathogen Interactions Room: Mt Temple A/B Speaker 5 of 6 Bronwyn M. Gunn, Massachusetts General Hospital, USA Short Talk: Alphavirus N-Linked Glycan Activation of the Host Complement System Contributes to Virus-Induced Inflammatory Disease
Wednesday, March 09 \| 8:00AM - 11:15AM Host-Pathogen Interactions Room: Mt Temple A/B Speaker 6 of 6 Hans Chun-Hung Lin, Academia Sinica, Taiwan Short Talk: Role for alpha-L-Fucosidase in the Control of Helicobacter pylori-Infected Gastric Cancer Cells
Wednesday, March 09 \| 9:20AM - 9:40AM Coffee Break Room: Heritage Hall
Wednesday, March 09 \| 11:15AM - 12:00PM Lunch
Wednesday, March 09 \| 12:00PM - 2:00PM Workshop: Glycobiology and Its Implications for HIV-1 Vaccin e Design Room: Mt Temple A/B Speaker 1 of 4 James Arthos, NIAID, National Institutes of Health, USA N-Linked Glycosylation Patterns in the gp120 Envelope Protein Impact HIV-1 Transmission
Wednesday, March 09 \| 12:00PM - 2:00PM Workshop: Glycobiology and Its Implications for HIV-1 Vaccin e Design Room: Mt Temple A/B Speaker 2 of 4 Heather Desaire, University of Kansas, USA Comparative Analysis of Recombinant gp140's, using a Glycosylation Site Specific Approach
Wednesday, March 09 \| 12:00PM - 2:00PM Workshop: Glycobiology and Its Implications for HIV-1 Vaccin e Design Room: Mt Temple A/B Speaker 3 of 4 Chris N. Scanlan, University of Oxford, UK Antibody Recognition of HIV Carbohydrates as a Template for Vaccine Design
Wednesday, March 09 \| 12:00PM - 2:00PM Workshop: Glycobiology and Its Implications for HIV-1 Vaccin e Design Room: Mt Temple A/B Speaker 4 of 4 Galit Alter, MIT and Harvard University, USA Differential Antibody Glycosylation as a Mechanism for Longterm Control of HIV
Wednesday, March 09 \| 2:00PM - 2:30PM Coffee Available Room: Heritage Hall
Wednesday, March 09 \| 3:00PM - 5:00PM Hematopoiesis and Lymphocyte Development Room: Mt Temple A/B Speaker 1 of 4 * Pamela Stanley, Albert Einstein College of Medicine, USA O-Fucose Glycans in Notch Signaling and T Cell Development
Wednesday, March 09 \| 3:00PM - 5:00PM Hematopoiesis and Lymphocyte Development Room: Mt Temple A/B Speaker 2 of 4 John B. Lowe, Genentech, Inc., USA Fucosylation-Dependent Control of Leukocyte Biology
Wednesday, March 09 \| 3:00PM - 5:00PM Hematopoiesis and Lymphocyte Development Room: Mt Temple A/B Speaker 3 of 4 Siew Cheng Wong, Singapore Immunology Network, Singapore Short Talk: Gene Expression Profiling Reveals Differential Expression of Carbohydrate Binding Receptor Proteins by the Three Human Monocyte Subsets
Wednesday, March 09 \| 3:00PM - 5:00PM Hematopoiesis and Lymphocyte Development Room: Mt Temple A/B Speaker 4 of 4 Martin K. Wild, Max Planck Institute of Molecular Biomedicine, Germany Short Talk: A Human Defect in alpha2,3-Sialylation Causing Thrombocytopenia and Reduced Selectin Binding
Wednesday, March 09 \| 5:00PM - 5:00PM On Own for Dinner
Wednesday, March 09 \| 5:30PM - 5:30PM Evening Out in Banff Optional bus trip for those interested in dining and shopping in the town of Banff. Approximate departure time from Banff is 9:00 PM.
Thursday, March 10 \| 7:00AM - 8:00AM Breakfast Room: Tom Wilson Dining Room
Thursday, March 10 \| 8:00AM - 11:00AM Autoimmunity and Chronic Inflammation Room: Mt Temple A/B Speaker 1 of 5 * Gabriel A. Rabinovich, Instituto de Biologia y Medicina Experimental, Argentina Tolerogenic Circuits Mediated by Galectin-Glycan Interactions in the Resolution of Autoimmune Inflammation
Thursday, March 10 \| 8:00AM - 11:00AM Autoimmunity and Chronic Inflammation Room: Mt Temple A/B Speaker 2 of 5 Rikard Holmdahl, Karolinska Institutet, Sweden Glycosylation Alterations of Autoantigens in Arthritis
Thursday, March 10 \| 8:00AM - 11:00AM Autoimmunity and Chronic Inflammation Room: Mt Temple A/B Speaker 3 of 5 Michael Demetriou, University of California, Irvine, USA N-Glycan Branching, T Cells and Autoimmunity
Thursday, March 10 \| 8:00AM - 11:00AM Autoimmunity and Chronic Inflammation Room: Mt Temple A/B Speaker 4 of 5 Hugh J. Willison, University of Glasgow, UK Antibody-Glycan Interactions in Neuronal Autoimmunity
Thursday, March 10 \| 8:00AM - 11:00AM Autoimmunity and Chronic Inflammation Room: Mt Temple A/B Speaker 5 of 5 George Buchlis, University of Pennsylvania and Children's Hospital of Philadelphia, USA Short Talk: Intrinsically Hyperactive and Hyperproliferative T Cells in Cmah-/- Mice
Thursday, March 10 \| 9:20AM - 9:40AM Coffee Break Room: Heritage Hall
Thursday, March 10 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Thursday, March 10 \| 4:30PM - 5:00PM Coffee Available Room: Heritage Hall
Thursday, March 10 \| 5:00PM - 7:00PM Tumor Immunity Room: Mt Temple A/B Speaker 1 of 4 * Minoru Fukuda, Sanford-Burnham Medical Research Institute, USA Endothelial Heparan Sulfate Controls Chemokine Presentation in the Recruitment of Lymphocytes and Dendritic Cells to Lymph Nodes and Inflammatory Tissues
Thursday, March 10 \| 5:00PM - 7:00PM Tumor Immunity Room: Mt Temple A/B Speaker 2 of 4 Olivera J. Finn, University of Pittsburgh School of Medicine, USA Differential Glycosylation of Self and Abnormal Self Antigens for Immunosurveillance of Premalignant and Malignant Lesions
Thursday, March 10 \| 5:00PM - 7:00PM Tumor Immunity Room: Mt Temple A/B Speaker 3 of 4 James W. Dennis, Mount Sinai Hospital, Canada N-glycan, Metabolism and Tumor Progression
Thursday, March 10 \| 5:00PM - 7:00PM Tumor Immunity Room: Mt Temple A/B Speaker 4 of 4 Pierre van der Bruggen, Ludwig Institute for Cancer Research, Belgium Short Talk: Is it Possible to Correct the Impaired Function of Human Infiltrating Lymphocytes?
Thursday, March 10 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Victoria
Thursday, March 10 \| 8:00PM - 11:00PM Entertainment Room: Victoria
Thursday, March 10 \| 8:00PM - 11:00PM Cash Bar Room: Victoria
Friday, March 11 \| 10:25AM - 10:25AM Departure *Session Chair.