Web Desc
Autophagy
Organizer(s): Ana Maria Cuervo, David C. Rubinsztein and Thomas P. Neufeld
Date: March 27 - April 01, 2011
Location: Whistler Conference Centre, Whistler, BC, Canada
Supported by the Directors' Fund
Summary of Meeting:
Autophagy is an essential cellular process that mediates continuous recycling of intracellular components and becomes an alternative source of energy when nutrients are scarce. Novel roles of autophagy in embryogenesis, development, cellular defense and cell death have emerged from recent studies, along with growing evidence of associations between autophagic dysfunction and disease. However, a deeper understanding of the molecular effectors and regulators of autophagy is still required if we are to effectively repair, restore or modulate autophagy in whole organisms for therapeutic purposes. This meeting will bring together experts in different areas of cell biology, genetics, cellular pathophysiology and metabolism to foster multidisciplinary discussions intended to advance our knowledge about the different autophagic mechanisms, their regulation and their contribution to normal cell functioning and to disease.
Scholarship Deadline: November 29 2010
Discounted Abstract Deadline: November 29 2010
Abstract Deadline: December 30 2010
Discounted Registration Deadline: January 27 2011
We gratefully acknowledge additional support for this conference from:
BioMarin Pharmaceutical Inc.Biosensis Pty LtdBoston Biochem, an R&D Systems CompanyCell Signaling Technology, Inc.Educational grant from Millennium Pharmaceuticals, Inc., The Takeda Oncology CompanyLandes BioscienceNovus Biologicals, Inc.
Pfizer Oncology
Seahorse Bioscience, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Pfizer Biopharmaceuticals
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Cell Therapy News
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA159718-01

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-02
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 27 | 3:00PM - 7:30PM
Registration
Room: Coat Check Area


Sunday, March 27 | 6:15PM - 7:15PM
Refreshments
Room: Grand Foyer/Mountainview


Sunday, March 27 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Sea to Sky C

Speaker 1 of 5
* Ana Maria Cuervo, Albert Einstein College of Medicine, USA

Sunday, March 27 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Sea to Sky C

Speaker 2 of 5
* David C. Rubinsztein, Cambridge Institute for Medical Research, UK

Sunday, March 27 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Sea to Sky C

Speaker 3 of 5
* Thomas P. Neufeld, University of Minnesota, USA

Sunday, March 27 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Sea to Sky C

Speaker 4 of 5
Aaron J. Ciechanover, Technion-Israel Institute of Technology, Israel
Proteolysis: From the Lysosome to Ubiquitin and the Proteasome

Sunday, March 27 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Sea to Sky C

Speaker 5 of 5
Yoshinori Ohsumi, Tokyo Institute of Technology, Japan
Autophagy in Yeast: Looking Back on the Past Two Decades and Future Perspective

Monday, March 28 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 1 of 7
* Thomas P. Neufeld, University of Minnesota, USA

Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 2 of 7
Daniel J. Klionsky, University of Michigan, USA
The Regulation of Macroautophagy

Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 3 of 7
Noboru Mizushima, University of Tokyo, Japan
(Part I) Hierarchical Relationships among Mammalian Atg Proteins
(PartII) Parkin-Dependent Selective Degradation of Mitochondria (Mitophagy)


Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 4 of 7
Roland L. Knorr, Max Planck Institute of Colloids and Interfaces, Germany
Short Talk: How Phagophores Bend into Autophagic Vesicles

Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 5 of 7
Jeannette S. Messer, University of Chicago, USA
Short Talk: ATG16L1 Mediates Lipidation of the mATG8 Family Members GABARAP, GATE-16, and LC3

Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 6 of 7
Sharon A. Tooze, Francis Crick Institute, UK
Exploring the Role of the Autophagy Specific PI3P Binding Protein, WIPI2

Monday, March 28 | 8:00AM - 11:15AM
Genetics of Autophagy: Novel Players
Room: Sea to Sky C

Speaker 7 of 7
Zvulun Elazar, Weizmann Institute of Science, Israel
Atg8s and Autophagosome Biogenesis

Monday, March 28 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer/Mountainview


Monday, March 28 | 11:15AM - 1:00PM
Poster Setup
Room: Sea to Sky A


Monday, March 28 | 11:15AM - 11:15AM
On Own for Lunch


Monday, March 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Sea to Sky A


Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 1 of 7
* Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA

Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 2 of 7
* Sharon A. Tooze, Francis Crick Institute, UK

Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 3 of 7
Ana Joaquina Jimenez, Institut Curie, France
Selective Recruitment of Autophagic Machineries upon Targeted Damage of Trafficking Organelles

Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 4 of 7
Jason S. King, Beatson Institute for Cancer Research, UK
Autophagy and Cellular Adaptation to Mechanical Stress in Dictyostelium and Mammalian Cells

Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 5 of 7
Anders Overbye, Institute for Cancer Research, Norway
Autophagic-Lysosomal Processing of Betaine:Homocysteine Methyltransferase (BHMT): Role of Asparaginyl Endopeptidase (Legumain)

Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 6 of 7
Steven V. Rødkær, University of Southern Denmark, Denmark
Mapping out Starvation Responses in Yeast by Proteomics

Monday, March 28 | 1:30PM - 2:45PM
Workshop 1: Novel Techniques to Track Autophagy
Room: Sea to Sky C

Speaker 7 of 7
Sebastian Schuck, HHMI/University of California, San Francisco, USA
Selective Autophagy of the Endoplasmic Reticulum by a Novel Microautophagic Mechanism

Monday, March 28 | 2:45PM - 3:15PM
Discussion: Novel Techniques to Track Autophagy
Discussants: Leon Murphy, Tamotsu Yoshimori, Zvulun Elazar

Monday, March 28 | 3:15PM - 4:00PM
Workshop 2: Autophagy and Disease: A Clinical Point of View
Room: Sea to Sky C

Speaker 1 of 5
* Beth Levine, University of Texas Southwestern Medical Center, USA

Monday, March 28 | 3:15PM - 4:00PM
Workshop 2: Autophagy and Disease: A Clinical Point of View
Room: Sea to Sky C

Speaker 2 of 5
* Ramnik Xavier, Massachusetts General Hospital, USA

Monday, March 28 | 3:15PM - 4:00PM
Workshop 2: Autophagy and Disease: A Clinical Point of View
Room: Sea to Sky C

Speaker 3 of 5
Andrey A. Parkhitko, Brigham and Women's Hospital Harvard Medical School, USA
Role of Autophagy in the Pathogenesis of Tuberous Sclerosis Complex

Monday, March 28 | 3:15PM - 4:00PM
Workshop 2: Autophagy and Disease: A Clinical Point of View
Room: Sea to Sky C

Speaker 4 of 5
Anna Katharina Simon, University of Oxford, UK
The Autophagy Protein Atg7 is Essential for Hematopoietic Stem Cell Maintenance and Leukemia Prevention

Monday, March 28 | 3:15PM - 4:00PM
Workshop 2: Autophagy and Disease: A Clinical Point of View
Room: Sea to Sky C

Speaker 5 of 5
Louis R. Lapierre, Brown University, USA
Autophagy Links Lipid Metabolism to Longevity in C. elegans

Monday, March 28 | 4:00PM - 4:30PM
Discussion: Autophagy and Disease: A Clinical Point of View
Discussants: Vojo Deretic, Noboru Mizushima, David Rubinsztein, Ana Maria Cuervo

Monday, March 28 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer/Mountainview


Monday, March 28 | 5:00PM - 7:00PM
Genetics of Autophagy: Novel Regulators
Room: Sea to Sky C

Speaker 1 of 5
* Daniel J. Klionsky, University of Michigan, USA

Monday, March 28 | 5:00PM - 7:00PM
Genetics of Autophagy: Novel Regulators
Room: Sea to Sky C

Speaker 2 of 5
Leon O. Murphy, Casma Therapeutics, USA
mTOR and Autophagy

Monday, March 28 | 5:00PM - 7:00PM
Genetics of Autophagy: Novel Regulators
Room: Sea to Sky C

Speaker 3 of 5
Xuejun Jiang, Memorial Sloan Kettering Cancer Center, USA
From ULK1 Complex-Mediated Autophagy Induction to Distinct Mechanism Governing Autophagosomal-Lysosomal Fusion

Monday, March 28 | 5:00PM - 7:00PM
Genetics of Autophagy: Novel Regulators
Room: Sea to Sky C

Speaker 4 of 5
Elaine Dunlop, Cardiff University, UK
Short Talk: ULK1 Inhibits mTORC1 through Multisite Raptor Phosphorylation and Hindrance of Substrate Binding

Monday, March 28 | 5:00PM - 7:00PM
Genetics of Autophagy: Novel Regulators
Room: Sea to Sky C

Speaker 5 of 5
Tamotsu Yoshimori, Osaka University, Japan
Mechanistic Insight into Membrane Dynamics in Mammalian Autophagy

Monday, March 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Grand Foyer/Mountainview


Monday, March 28 | 7:30PM - 10:00PM
Poster Session 1
Room: Sea to Sky A/Grand Foyer


Tuesday, March 29 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Tuesday, March 29 | 8:00AM - 11:00AM
Autophagy in Cell Biology and Cell Function
Room: Sea to Sky C

Speaker 1 of 6
* Patrice Codogno, INSERM, France

Tuesday, March 29 | 8:00AM - 11:00AM
Autophagy in Cell Biology and Cell Function
Room: Sea to Sky C

Speaker 2 of 6
Thomas P. Neufeld, University of Minnesota, USA
Intersections between Autophagy and the Cell Growth Machinery

Tuesday, March 29 | 8:00AM - 11:00AM
Autophagy in Cell Biology and Cell Function
Room: Sea to Sky C

Speaker 3 of 6
Richard J. Youle, NINDS, National Institutes of Health, USA
Damage control: How the Pink-1/Parkin Pathway can Regulate the Removal of Damaged Mitochondria by Autophagy

Tuesday, March 29 | 8:00AM - 11:00AM
Autophagy in Cell Biology and Cell Function
Room: Sea to Sky C

Speaker 4 of 6
Ana Maria Cuervo, Albert Einstein College of Medicine, USA
Selective Autophagy in Aging Pathophysiology

Tuesday, March 29 | 8:00AM - 11:00AM
Autophagy in Cell Biology and Cell Function
Room: Sea to Sky C

Speaker 5 of 6
Marc D. Meneghini, University of Toronto, Canada
Short Talk: Sporophagy: Developmentally Programmed Autophagic Destruction of Whole Nuclei during Yeast Gametogenesis

Tuesday, March 29 | 8:00AM - 11:00AM
Autophagy in Cell Biology and Cell Function
Room: Sea to Sky C

Speaker 6 of 6
Ivan Dikic, Goethe University Medical School, Germany
Regulation of Selective Autophagy by Receptor Phosphorylation

Tuesday, March 29 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer/Mountainview


Tuesday, March 29 | 11:00AM - 1:00PM
Poster Setup
Room: Sea to Sky A


Tuesday, March 29 | 11:00AM - 11:00AM
On Own for Lunch


Tuesday, March 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Sea to Sky A


Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 1 of 7
* Daniel J. Klionsky, University of Michigan, USA

Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 2 of 7
* Thomas P. Neufeld, University of Minnesota, USA

Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 3 of 7
Takahiko Akematsu, York University, Canada
Gigantic Macroautophagy in Programmed Nuclear Death of Tetrahymena Thermophila

Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 4 of 7
Diane C. Bassham, Iowa State University, USA
Degradation of the Endoplasmic Reticulum by Autophagy during ER Stress in Plants

Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 5 of 7
Guang-Chao Chen, Academia Sinica, Taiwan
Atg1-Mediated Myosin-II Activation Regulates Autophagy in Drosophila and Mammalian Cells

Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 6 of 7
Amy Kiger, University of California, San Diego, USA
Class II PI3-Kinase and Regulators of Membrane Trafficking Coordinately Regulate Autophagy

Tuesday, March 29 | 1:30PM - 2:45PM
Workshop 3: Non-Mammalian Autophagy: Advantages/Limitations
Room: Sea to Sky C

Speaker 7 of 7
Dennis Pultz, University of Southern Denmark, Denmark
Investigating Temporal Changes in the Yeast Phosphoproteome upon Fatty Acid Starvation

Tuesday, March 29 | 2:45PM - 3:00PM
Discussion: Non-Mammalian Autophagy: Advantages/Limitations
Discussants: Malene Hansen, Sharon Gorski, Daniel Klionsky

Tuesday, March 29 | 3:00PM - 4:00PM
Workshop 4: Large Screening and Omics in Autophagy
Room: Sea to Sky C

Speaker 1 of 5
* David C. Rubinsztein, Cambridge Institute for Medical Research, UK

Tuesday, March 29 | 3:00PM - 4:00PM
Workshop 4: Large Screening and Omics in Autophagy
Room: Sea to Sky C

Speaker 2 of 5
Benoît Pasquier, Sanofi Aventis, France
High throughput Screening for Autophagy Inhibitors

Tuesday, March 29 | 3:00PM - 4:00PM
Workshop 4: Large Screening and Omics in Autophagy
Room: Sea to Sky C

Speaker 3 of 5
Chih-Wen Shu, Kaohsiung Veterans General Hospital, Taiwan
High-Throughput Screening for Small Molecule Inhibitors of Autophagins/Atg4

Tuesday, March 29 | 3:00PM - 4:00PM
Workshop 4: Large Screening and Omics in Autophagy
Room: Sea to Sky C

Speaker 4 of 5
Rhea M. Sumpter, Jr., University of Texas Southwestern Medical Center, USA
Image-Based Genome-Wide siRNA Screen Identifies Host Factors Involved in Selective Autophagy

Tuesday, March 29 | 3:00PM - 4:00PM
Workshop 4: Large Screening and Omics in Autophagy
Room: Sea to Sky C

Speaker 5 of 5
* Eileen P. White, Rutgers Cancer Institute of New Jersey, USA
PROS and CONS of the Major Metabolomics Technics

Tuesday, March 29 | 4:00PM - 4:30PM
Discussion: Large Screening and Omics in Autophagy
Discussants: Eileen P. White, Robert Abraham

Tuesday, March 29 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer/Mountainview


Tuesday, March 29 | 5:00PM - 7:00PM
Autophagy in Response to Stress and Injury
Room: Sea to Sky C

Speaker 1 of 6
* Noboru Mizushima, University of Tokyo, Japan

Tuesday, March 29 | 5:00PM - 7:00PM
Autophagy in Response to Stress and Injury
Room: Sea to Sky C

Speaker 2 of 6
Beth Levine, University of Texas Southwestern Medical Center, USA
Bcl-2 Regulated Autophagy in Exercise and Resistance

Tuesday, March 29 | 5:00PM - 7:00PM
Autophagy in Response to Stress and Injury
Room: Sea to Sky C

Speaker 3 of 6
Patricia Boya, Centro de Investigaciones Biológicas, CSIC, Spain
Short Talk: Autophagy Promotes Survival of Retinal Ganglion Cells after Optic Nerve Axotomy in Mice

Tuesday, March 29 | 5:00PM - 7:00PM
Autophagy in Response to Stress and Injury
Room: Sea to Sky C

Speaker 4 of 6
Claudio A. Hetz, University of Chile, Chile
Homeostatic Connection between the Unfolded Protein Response (UPR) and Autophagy in Neurodegeneration

Tuesday, March 29 | 5:00PM - 7:00PM
Autophagy in Response to Stress and Injury
Room: Sea to Sky C

Speaker 5 of 6
N. Tony Eissa, Baylor College of Medicine, USA
Short Talk: p62 Mediates a Novel Cytosolic Response to Unfolded Proteins Linking Inflammation, ER Stress and Metabolic Syndrome

Tuesday, March 29 | 5:00PM - 7:00PM
Autophagy in Response to Stress and Injury
Room: Sea to Sky C

Speaker 6 of 6
Conrad C. Weihl, Washington University School of Medicine, USA
Short Talk: VCP Coordinates the Degradation of Ubiquitinated Substrates via Multiple Pathways

Tuesday, March 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Grand Foyer/Mountainview


Tuesday, March 29 | 7:30PM - 10:00PM
Poster Session 2
Room: Sea to Sky A/Grand Foyer


Wednesday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 1 of 7
* Ana Maria Cuervo, Albert Einstein College of Medicine, USA

Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 2 of 7
Francesco Cecconi, University of Rome Tor Vergata, Italy
Physiological and Pathological Regulation of the Pro-Autophagic Factor Ambra1



Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 3 of 7
Daniela Laura Papademetrio, University of Buenos Aires, Argentina
Short Talk: Autophagy Prevents Apoptotic Death in Pancreatic Tumor

Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 4 of 7
Andrea Ballabio, Telethon Institute of Genetics and Medicine, Italy
TFEB Links Autophagy to Lysosomal Biogenesis


Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 5 of 7
Nivetha Ramachandran, SickKids, Canada
X-Linked Myopathy with Excessive Autophagy

Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 6 of 7
Ralph A. Nixon, New York University, Langone Medical Center, USA
Autophagy in the Alzheimer's Brain

Wednesday, March 30 | 8:00AM - 11:15AM
Autophagy in Disease I
Room: Sea to Sky C

Speaker 7 of 7
Victor Shengkan Jin, Rutgers University, USA
Short Talk: Autophagy in Differentiation and Mitochondrial Homeostasis Control of White Adipose Tissue: Implications in Obesity and Type II Diabetes

Wednesday, March 30 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer/Mountainview


Wednesday, March 30 | 11:15AM - 1:00PM
Poster Setup
Room: Sea to Sky A


Wednesday, March 30 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Wednesday, March 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Sea to Sky A


Wednesday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer/Mountainview


Wednesday, March 30 | 5:00PM - 7:00PM
Autophagy in Disease II
Room: Sea to Sky C

Speaker 1 of 6
* † Herbert (Skip) W. Virgin, Vir Biotechnology, USA

Wednesday, March 30 | 5:00PM - 7:00PM
Autophagy in Disease II
Room: Sea to Sky C

Speaker 2 of 6
Vojo Deretic, University of New Mexico Health Sciences Center, USA
Autophagy: An Emerging Immunological Paradigm

Wednesday, March 30 | 5:00PM - 7:00PM
Autophagy in Disease II
Room: Sea to Sky C

Speaker 3 of 6
Marija Cemma, Hospital for Sick Children, Canada
Short Talk: The Ubiquitin-Binding Adaptor Proteins p62/SQSTM1 and NDP52 are Recruited Independently to Bacteria-Associated Microdomains to Target Salmonella to the Autophagy Pathway

Wednesday, March 30 | 5:00PM - 7:00PM
Autophagy in Disease II
Room: Sea to Sky C

Speaker 4 of 6
Iryna Monastyrska, Utrecht University, Netherlands
Short Talk: LC3-I is Abused by Positive-Stranded RNA Viruses for Replication on ER-Derived Vesicles

Wednesday, March 30 | 5:00PM - 7:00PM
Autophagy in Disease II
Room: Sea to Sky C

Speaker 5 of 6
Seungmin (Sam) Hwang, University of Chicago, USA
Short Talk: ATG5 is Required for Interferon-gamma to Control Murine Norovirus Replication

Wednesday, March 30 | 5:00PM - 7:00PM
Autophagy in Disease II
Room: Sea to Sky C

Speaker 6 of 6
Ramnik Xavier, Massachusetts General Hospital, USA
Integrative Genomics Approaches to Gene Discovery in Autophagy and Disease

Wednesday, March 30 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Grand Foyer/Mountainview


Wednesday, March 30 | 7:30PM - 10:00PM
Poster Session 3
Room: Sea to Sky A/Grand Foyer


Thursday, March 31 | 7:00AM - 8:00AM
Breakfast
Room: Sea to Sky A


Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 1 of 7
* Beth Levine, University of Texas Southwestern Medical Center, USA

Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 2 of 7
Kevin M. Ryan, Beatson Institute for Cancer Research, UK
Autophagy in Cancer Development and Tumor Cell Death

Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 3 of 7
Guido Kroemer, Cordeliers Research Center, France
Autophagy: A Cytoprotective Mechanism that Shapes Anticancer Immune Responses

Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 4 of 7
Robert T. Abraham, Vividion Therapeutics, USA
mTOR at the Crossroads of Cancer Metabolism and Cancer Therapy



Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 5 of 7
Maryam Mehrpour, INSERM, France
Short Talk: Self Renewal of Breast Cancer Stem Cells is Dependent on Beclin 1

Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 6 of 7
Alec Kimmelman, New York University Langone Medical Center, USA
Short Talk: Pancreatic Cancers are Addicted to Autophagy for Tumor Maintenance

Thursday, March 31 | 8:00AM - 11:15AM
Autophagy, Cell Death and Cancer
Room: Sea to Sky C

Speaker 7 of 7
Eileen P. White, Rutgers Cancer Institute of New Jersey, USA
Targeting Autophagy in Cancer

Thursday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Grand Foyer/Mountainview


Thursday, March 31 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Thursday, March 31 | 4:30PM - 5:00PM
Coffee Available
Room: Grand Foyer/Mountainview


Thursday, March 31 | 5:00PM - 6:15PM
Autophagy: Hot and Controversial Topics
Room: Sea to Sky C

Speaker 1 of 4
* Sharon A. Tooze, Francis Crick Institute, UK

Thursday, March 31 | 5:00PM - 6:15PM
Autophagy: Hot and Controversial Topics
Room: Sea to Sky C

Speaker 2 of 4
* Vojo Deretic, University of New Mexico Health Sciences Center, USA

Thursday, March 31 | 5:00PM - 6:15PM
Autophagy: Hot and Controversial Topics
Room: Sea to Sky C

Speaker 3 of 4
Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA
Autophagy Regulation by Mitochondria after Starvation

Thursday, March 31 | 5:00PM - 6:15PM
Autophagy: Hot and Controversial Topics
Room: Sea to Sky C

Speaker 4 of 4
David C. Rubinsztein, Cambridge Institute for Medical Research, UK
The Plasma Membrane Contributes to Pre-Autophagosomal Structures

Thursday, March 31 | 6:15PM - 7:00PM
Round Table Discussion: Mitophagy

Speaker 1 of 4
* Richard J. Youle, NINDS, National Institutes of Health, USA

Thursday, March 31 | 6:15PM - 7:00PM
Round Table Discussion: Mitophagy

Speaker 2 of 4
Sih-han Wang, University of Texas MD Anderson Cancer Center, USA
Short Talk: A Tale of Two Mitophagies: Parkin-Dependent and -Independent Pathways

Thursday, March 31 | 6:15PM - 7:00PM
Round Table Discussion: Mitophagy

Speaker 3 of 4
Kristi Lynn Norris, Duke University Medical Center, USA
Short Talk: Parkin Maintains Mitochondrial Quality by Promoting Stress-Induced Mitochondrial Fusion and Mitophagy

Thursday, March 31 | 6:15PM - 7:00PM
Round Table Discussion: Mitophagy

Speaker 4 of 4
Wim Vandenberghe, University Hospitals Leuven, Belgium
Short Talk: Parkin Interacts with Ambra1 to Induce Mitophagy

Thursday, March 31 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Grand Foyer/Mountainview


Thursday, March 31 | 8:00PM - 11:00PM
Entertainment
Room: Sea to Sky A


Thursday, March 31 | 8:00PM - 11:00PM
Cash Bar
Room: Sea to Sky A


Friday, April 01 | 10:25AM - 10:25AM
Departure


*Session Chair.