Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Epigenomics (2015Z2)
Cancer Epigenetics (2014Q1)
Epigenetic Programming and Inheritance (2014D2)
Nutrition, Epigenetics and Human Disease (2013B5)
Epigenomics (2012J3)

Web Desc
Environmental Epigenomics and Disease Susceptibility Organizer(s): Randy L. Jirtle, Moshe Szyf and Frederick L. Tyson Date: March 27 - April 01, 2011 Location: Grove Park Inn Resort & Spa, Asheville, NC, USA Supported by the Directors' Fund Summary of Meeting: There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs in cells are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this conference is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome. Epigenetic research promises to markedly improve our ability to diagnosis, prevent, and treat the pathological conditions of humans; however, it also introduces unique legal and ethical issues. These will also be discussed. Scholarship Deadline: November 30 2010 Discounted Abstract Deadline: November 30 2010 Abstract Deadline: December 31 2010 Discounted Registration Deadline: January 28 2011 We gratefully acknowledge additional support for this conference from: We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 5R13DK084688-02 National Institute of Environmental Health Sciences (NIEHS) Grant No. 1R13ES020113-01 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Environmental Epigenomics and Disease Susceptibility

Organizer(s): Randy L. Jirtle, Moshe Szyf and Frederick L. Tyson

Date: March 27 - April 01, 2011
Location: Grove Park Inn Resort & Spa, Asheville, NC, USA

Supported by the Directors' Fund

Summary of Meeting:

There are now compelling human epidemiological and animal experimental data that indicate the risk of developing adult-onset complex diseases and neurological disorders are influenced by persistent epigenetic adaptations in response to prenatal and early postnatal exposures to environmental factors. Epigenetics refers to heritable changes in gene function that occur without a change in the sequence of the DNA. The main components of the epigenetic code are DNA methylation, histone modifications, and non-coding RNAs. The epigenetic programs in cells are normally faithfully reproduced during mitosis. Moreover, they can also be maintained during meiosis, resulting in epigenetic transgenerational disease inheritance, and potentially introducing phenotypic variation that is selected for in the evolution of new species. The objective of this conference is to provide evidence that environmental exposures during early development can alter the risk of developing medical conditions, such as asthma, autism, cancer, cardiovascular disease, diabetes, obesity, and schizophrenia later in life by modifying the epigenome. Epigenetic research promises to markedly improve our ability to diagnosis, prevent, and treat the pathological conditions of humans; however, it also introduces unique legal and ethical issues. These will also be discussed.

Scholarship Deadline: November 30 2010

Discounted Abstract Deadline: November 30 2010

Abstract Deadline: December 31 2010

Discounted Registration Deadline: January 28 2011

We gratefully acknowledge additional support for this conference from:

Rete Mirabile Fund of Triangle Community Foundation

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-02

National Institute of Environmental Health Sciences (NIEHS)
Grant No. 1R13ES020113-01

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 27 \| 3:00PM - 7:30PM Registration Room: Vanderbilt
Sunday, March 27 \| 6:15PM - 7:15PM Refreshments Room: Grand Ballroom B-C
Sunday, March 27 \| 7:15PM - 8:30PM Welcome and Keynote Address Room: Grand Ballroom A Speaker 1 of 1 Eva Jablonka, Tel Aviv University, Israel Being Fit in Four Dimensions
Monday, March 28 \| 7:30AM - 8:30AM Breakfast Room: Grand Ballroom B-C
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 1 of 7 * Cathrine Hoyo, Duke University, USA
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 2 of 7 Ezra S. Susser, Columbia University and New York State Psychiatric Institute, USA Prenatal Famine, Epigenetics, and Schizophrenia
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 3 of 7 Marcus Pembrey, University College London, UK Nature of Human Transgenerational Responses
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 4 of 7 Gudrun E. Moore, Institute of Child Health, UK Epigenetic Dysregulation of Imprinting Influences Birth Weight and Disease Susceptibility in Humans
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 5 of 7 Claudine Junien, INRA, France Nutritional and Metabolic Programming: Sexual Dimorphism Epigenetics
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 6 of 7 Martha Susiarjo, University of Pennsylvania, USA Short Talk: Effects of Bisphenol A Exposure on Genomic Imprinting in the Mouse
Monday, March 28 \| 8:30AM - 11:45AM Fetal Origins of Adult Disease Susceptibility Room: Grand Ballroom A Speaker 7 of 7 Ruijun Han, University of Minnesota, USA Short Talk: Prenatal Stress Up-Regulates NPY Expression and Leads to Gender-Specific Abdominal Obesity and Glucose Intolerance: Possible Role of Epigenetics
Monday, March 28 \| 9:50AM - 10:10AM Coffee Break Room: Grand Ballroom B-C
Monday, March 28 \| 11:45AM - 1:00PM Poster Setup Room: Grand Ballroom B-C
Monday, March 28 \| 11:45AM - 11:45AM On Own for Lunch and Recreation
Monday, March 28 \| 1:00PM - 10:00PM Poster Viewing Room: Grand Ballroom B-C
Monday, March 28 \| 4:30PM - 5:00PM Coffee Available Room: Grand Ballroom Foyer
Monday, March 28 \| 5:00PM - 7:00PM Epigenetic Mechanisms of Gene Regulation Room: Grand Ballroom A Speaker 1 of 5 * Douglas A. Bell, NIEHS, National Institutes of Health, USA
Monday, March 28 \| 5:00PM - 7:00PM Epigenetic Mechanisms of Gene Regulation Room: Grand Ballroom A Speaker 2 of 5 Ian C. Wood, University of Leeds, UK Chromatin Crosstalk in Development and Disease
Monday, March 28 \| 5:00PM - 7:00PM Epigenetic Mechanisms of Gene Regulation Room: Grand Ballroom A Speaker 3 of 5 Joseph R. Ecker, The Salk Institute for Biological Studies, USA Sequencing the Epigenomes of Plants and People
Monday, March 28 \| 5:00PM - 7:00PM Epigenetic Mechanisms of Gene Regulation Room: Grand Ballroom A Speaker 4 of 5 Victor V. Lobanenkov, NIAID, National Institutes of Health, USA CTCF Dysfunction, Epigenetic Deregulation, and Cancer Susceptibility
Monday, March 28 \| 5:00PM - 7:00PM Epigenetic Mechanisms of Gene Regulation Room: Grand Ballroom A Speaker 5 of 5 Sonja J. Prohaska, University of Leipzig, Germany Short Talk: Analytical Analysis and Modeling of the Dynamic Epigenome
Monday, March 28 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Grand Ballroom B-C
Monday, March 28 \| 7:30PM - 10:00PM Poster Session 1 Room: Grand Ballroom B-C
Tuesday, March 29 \| 7:30AM - 8:30AM Breakfast Room: Grand Ballroom B-C
Tuesday, March 29 \| 8:30AM - 11:45AM In vitro Fertilization, Cloning and Stem Cells Room: Grand Ballroom A Speaker 1 of 6 * J. Richard Chaillet, University of Pittsburgh, USA
Tuesday, March 29 \| 8:30AM - 11:45AM In vitro Fertilization, Cloning and Stem Cells Room: Grand Ballroom A Speaker 2 of 6 James A. Thomson, Morgridge Institute for Research, University of Wisconsin, USA Epigenetic State and Genetic Stability of Human iPS Cells
Tuesday, March 29 \| 8:30AM - 11:45AM In vitro Fertilization, Cloning and Stem Cells Room: Grand Ballroom A Speaker 3 of 6 Louise Laurent, University of California, San Diego, USA The Epigenomics of Human Pluripotent Stem Cells
Tuesday, March 29 \| 8:30AM - 11:45AM In vitro Fertilization, Cloning and Stem Cells Room: Grand Ballroom A Speaker 4 of 6 Wolf Reik, Babraham Institute, UK Mechanisms and Functions of Epigenetic Reprogramming in Mammalian Development
Tuesday, March 29 \| 8:30AM - 11:45AM In vitro Fertilization, Cloning and Stem Cells Room: Grand Ballroom A Speaker 5 of 6 Rosanna Weksberg, Hospital for Sick Children, Canada Short Talk: Increased Frequency of Multilocus Loss of Methylation in Beckwith Wiedemann Syndrome Cases Conceived using Assisted Reproductive Technologies
Tuesday, March 29 \| 8:30AM - 11:45AM In vitro Fertilization, Cloning and Stem Cells Room: Grand Ballroom A Speaker 6 of 6 Toshi Shioda, Massachusetts General Hospital, USA Short Talk: Specific Erasure of the Abnormal Biallelic Hypermethylation at the Gtl2/Meg3 Intragenic DMR in Mouse Induced Pluripotent Stem Cells (iPSCs) during In Vitro Derivation of Germline Cells
Tuesday, March 29 \| 9:50AM - 10:10AM Coffee Break Room: Grand Ballroom B-C
Tuesday, March 29 \| 11:45AM - 1:00PM Poster Setup Room: Grand Ballroom B-C
Tuesday, March 29 \| 11:45AM - 11:45AM On Own for Lunch and Recreation
Tuesday, March 29 \| 1:00PM - 10:00PM Poster Viewing Room: Grand Ballroom B-C
Tuesday, March 29 \| 4:30PM - 5:00PM Coffee Available Room: Grand Ballroom Foyer
Tuesday, March 29 \| 5:00PM - 7:15PM Postnatal Epigenetic Programming of the Brain Room: Grand Ballroom A Speaker 1 of 6 * Ian C.G. Weaver, Centre for Addiction and Mental Health, Canada
Tuesday, March 29 \| 5:00PM - 7:15PM Postnatal Epigenetic Programming of the Brain Room: Grand Ballroom A Speaker 2 of 6 Moshe Szyf, McGill University, Canada Early Life Environment and the Epigenome
Tuesday, March 29 \| 5:00PM - 7:15PM Postnatal Epigenetic Programming of the Brain Room: Grand Ballroom A Speaker 3 of 6 Barry Keverne, University of Cambridge, UK Epigenetics, Maternal Brain Evolution and Behavior
Tuesday, March 29 \| 5:00PM - 7:15PM Postnatal Epigenetic Programming of the Brain Room: Grand Ballroom A Speaker 4 of 6 J. David Sweatt, University of Alabama at Birmingham, USA Epigenetic Mechanisms in Memory Formation
Tuesday, March 29 \| 5:00PM - 7:15PM Postnatal Epigenetic Programming of the Brain Room: Grand Ballroom A Speaker 5 of 6 Syed Wasem Bihaqi, University of Rhode Island, USA Short Talk: Alzheimer’s Disease: Epigenetic Intermediates and Exposure to Pb in an in-vitro Model
Tuesday, March 29 \| 5:00PM - 7:15PM Postnatal Epigenetic Programming of the Brain Room: Grand Ballroom A Speaker 6 of 6 Eunah Kim, University of Texas MD Anderson Cancer Center, USA Short Talk: Altered Chromatin Structure Induced by Hyperexpanded GAA Repeats in Friedreich’s Ataxia
Tuesday, March 29 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Grand Ballroom B-C
Tuesday, March 29 \| 7:30PM - 10:00PM Poster Session 2 Room: Grand Ballroom B-C
Wednesday, March 30 \| 7:30AM - 8:30AM Breakfast Room: Grand Ballroom B-C
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 1 of 7 * Janos Zempleni, University of Nebraska, Lincoln, USA
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 2 of 7 Maria Berdasco, IDIBELL, Spain Human Cancer Epigenetics
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 3 of 7 Frederica P. Perera, Columbia University, USA Prenatal Environmental Exposures to Common Hydrocarbons PAH and BPA
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 4 of 7 Dana C. Dolinoy, University of Michigan School of Public Health, USA Complex Diseases: Epigenetic Manifestation of Environmental Exposures
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 5 of 7 Cheryl L. Walker, Baylor College of Medicine, USA Fetal and Early Postnatal Environmental Exposures and Female Reproductive Health Effects
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 6 of 7 Robert Lyle, Oslo University Hospital, Norway Short Talk: DNA Methylation and Gene Expression in Monozygotic Twins Discordant for Psoriasis
Wednesday, March 30 \| 8:30AM - 11:15AM Epigenetics and Complex Diseases Room: Grand Ballroom A Speaker 7 of 7 Carrie V. Breton, University of Southern California, USA Short Talk: Air Pollution is Associated with DNA Methylation in Inducible Nitric Oxide Synthase
Wednesday, March 30 \| 9:50AM - 10:10AM Coffee Break Room: Grand Ballroom B-C
Wednesday, March 30 \| 11:45AM - 1:00PM Poster Setup Room: Grand Ballroom B-C
Wednesday, March 30 \| 11:45AM - 11:45AM On Own for Lunch and Recreation
Wednesday, March 30 \| 1:00PM - 10:00PM Poster Viewing Room: Grand Ballroom B-C
Wednesday, March 30 \| 4:30PM - 5:00PM Coffee Available Room: Grand Ballroom Foyer
Wednesday, March 30 \| 5:00PM - 7:15PM Epigenetic Transgenerational Inheritance Room: Grand Ballroom A Speaker 1 of 6 * Patrick O. McGowan, University of Toronto, Canada
Wednesday, March 30 \| 5:00PM - 7:15PM Epigenetic Transgenerational Inheritance Room: Grand Ballroom A Speaker 2 of 6 Emma Whitelaw, Queensland Institute of Medical Research, Australia Transgenerational Epigenetic Inheritance
Wednesday, March 30 \| 5:00PM - 7:15PM Epigenetic Transgenerational Inheritance Room: Grand Ballroom A Speaker 3 of 6 Michael K. Skinner, Washington State University, USA Epigenetic Transgenerational Inheritance Following Exposure to Endocrine Disruptors
Wednesday, March 30 \| 5:00PM - 7:15PM Epigenetic Transgenerational Inheritance Room: Grand Ballroom A Speaker 4 of 6 Douglas Ruden, Wayne State University, USA Transgenerational Epigenetic Inheritance in Drosophila
Wednesday, March 30 \| 5:00PM - 7:15PM Epigenetic Transgenerational Inheritance Room: Grand Ballroom A Speaker 5 of 6 Yoav Soen, Weizmann Institute of Science, Israel Short Talk: Heritable Epigenesis is beyond the Developmental Program
Wednesday, March 30 \| 5:00PM - 7:15PM Epigenetic Transgenerational Inheritance Room: Grand Ballroom A Speaker 6 of 6 Jennifer T. Wolstenholme, University of Virginia, USA Short Talk: Bisphenol A Alters the Epigenome and Social Behavior over Multiple Generations
Wednesday, March 30 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Grand Ballroom B-C
Wednesday, March 30 \| 7:30PM - 10:00PM Poster Session 3 Room: Grand Ballroom B-C
Thursday, March 31 \| 7:30AM - 8:30AM Breakfast Room: Grand Ballroom B-C
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 1 of 7 * Simon G. Gregory, Duke University, USA
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 2 of 7 Art Petronis, University of Toronto, Canada Epigenomics and Complex Psychiatric Disease
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 3 of 7 Janine M. LaSalle, University of California, Davis, USA Epigenetics at the Interface of Genetic and Environmental Risk Factors for Autism Spectrum Disorders
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 4 of 7 Farah D. Lubin, University of Alabama at Birmingham, USA Histone Methylation in Memory Formation and Aging
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 5 of 7 Lorraine Young, University of Nottingham, UK Modelling Nutritional Programming of the Human Preimplantation Embryo using Embryonic Stem Cells
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 6 of 7 Fatemeh G. Haghighi, Columbia University, USA Short Talk: Role of DNA Methylation in Brain Aging and Depression
Thursday, March 31 \| 8:30AM - 11:30AM Epigenetics and Neurological Disorders Room: Grand Ballroom A Speaker 7 of 7 Nagamohan Kommu, BITS Pilani Hyderabad Campus, India Short Talk: Identification of Candidate Epimutations in One Autism and One Schizophrenia Brain Sample
Thursday, March 31 \| 9:50AM - 10:10AM Coffee Break Room: Grand Ballroom B-C
Thursday, March 31 \| 11:30AM - 11:30AM On Own for Lunch and Recreation
Thursday, March 31 \| 4:30PM - 5:00PM Coffee Available Room: Grand Ballroom Foyer
Thursday, March 31 \| 5:00PM - 7:00PM Mammalian Evolution and Disease Susceptibility Room: Grand Ballroom A Speaker 1 of 5 * Catherine (Kay) M. Nolan, University College Dublin, Ireland
Thursday, March 31 \| 5:00PM - 7:00PM Mammalian Evolution and Disease Susceptibility Room: Grand Ballroom A Speaker 2 of 5 David Haig, Harvard University, USA Transfers and Transitions: The Evolution of Human Life History
Thursday, March 31 \| 5:00PM - 7:00PM Mammalian Evolution and Disease Susceptibility Room: Grand Ballroom A Speaker 3 of 5 Christopher Badcock, London School of Economics and Political Science, UK The Imprinted Brain Theory: How Genes Set the Balance between Autism and Psychosis
Thursday, March 31 \| 5:00PM - 7:00PM Mammalian Evolution and Disease Susceptibility Room: Grand Ballroom A Speaker 4 of 5 Randy L. Jirtle, University of Wisconsin-Madison, USA Biological Consequences of the Divergent Evolution of IGF2R Imprinting
Thursday, March 31 \| 5:00PM - 7:00PM Mammalian Evolution and Disease Susceptibility Room: Grand Ballroom A Speaker 5 of 5 Jan Engelhardt, University of Leipzig, Germany Short Talk: Evolution of the HOTAIR ncRNA in Vertebrates: Structural and Functional Flexibility of a Scaffold
Thursday, March 31 \| 7:00PM - 7:55PM Closing Remarks Room: Grand Ballroom A Speaker 1 of 1 Mark Rothstein, University of Louisville School of Medicine, USA Legal and Ethical Implications of Epigenetics
Thursday, March 31 \| 7:30PM - 8:30PM Social Hour with Lite Bites Room: Grand Ballroom B-C
Thursday, March 31 \| 8:30PM - 11:30PM Entertainment Room: Grand Ballroom B-C
Thursday, March 31 \| 8:30PM - 11:30PM Cash Bar Room: Grand Ballroom B-C
Friday, April 01 \| 10:25AM - 10:25AM Departure *Session Chair.