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Web Desc
Metabolic Responses to Extreme Conditions Organizer(s): John R. Speakman, Jan Nedergaard and Sandra L. Martin Date: April 01 - 05, 2011 Location: Big Sky Resort, Big Sky, MT, USA Supported by the Directors' Fund Summary of Meeting: Animals face a number of extreme stressors to which they must respond. Generally researchers have focused on responses to particular stressful situations, and hence research communities have grown up around these specialized areas. The aim of this meeting is to draw together several of these research communities in a unique interdisciplinary meeting. The aim of bringing such communities together is to allow researchers to explore parallel responses of animals to rather different ‘extremes’. We anticipate this will allow the emergence of common themes and provide an opportunity for researchers to interact with others outside their main areas of interest. Scholarship Deadline: December 1 2010 Discounted Abstract Deadline: December 1 2010 Abstract Deadline: January 31 2011 Discounted Registration Deadline: February 18 2011 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 5R13DK084688-02 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Metabolic Responses to Extreme Conditions

Organizer(s): John R. Speakman, Jan Nedergaard and Sandra L. Martin

Date: April 01 - 05, 2011
Location: Big Sky Resort, Big Sky, MT, USA

Supported by the Directors' Fund

Summary of Meeting:

Animals face a number of extreme stressors to which they must respond. Generally researchers have focused on responses to particular stressful situations, and hence research communities have grown up around these specialized areas. The aim of this meeting is to draw together several of these research communities in a unique interdisciplinary meeting. The aim of bringing such communities together is to allow researchers to explore parallel responses of animals to rather different ‘extremes’. We anticipate this will allow the emergence of common themes and provide an opportunity for researchers to interact with others outside their main areas of interest.

Scholarship Deadline: December 1 2010

Discounted Abstract Deadline: December 1 2010

Abstract Deadline: January 31 2011

Discounted Registration Deadline: February 18 2011

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-02

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Friday, April 01 \| 3:00PM - 7:30PM Registration Room: Lower Atrium
Friday, April 01 \| 6:15PM - 7:15PM Refreshments Room: Lower Atrium
Friday, April 01 \| 7:15PM - 8:30PM Welcome and Keynote Address Room: Jefferson Speaker 1 of 1 Yvon Le Maho, Université de Strasbourg and Centre National de la Recherche Scientifique, France How Antarctic Penguins Cope with Extreme Conditions and How They May Fail Due to Climate Change
Saturday, April 02 \| 7:00AM - 8:00AM Breakfast Room: Madison
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 7 of 7 Jennifer H. Stern, University of Arizona Cancer Center, USA Short Talk: The Impact of Calorie Restriction on Whole Body Energy Metabolism in p66Shc(-/-) Mice
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 6 of 7 Kevork Hagopian, University of California, Davis, USA Short Talk: The Influence of Calorie Restriction on H2O2 Production in Mitochondrial Subpopulations from Mouse Liver
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 5 of 7 Deborah M. Kristan, California State University San Marcos, USA Calorie Restriction Produces a Strong Immune Response but does not Protect against Parasite Infection
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 4 of 7 John Speakman, Institute of Genetics and Developmental Biology, CAS, China The Effects of Graded Caloric Restriction on Metabolomic Profiles in Mice
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 3 of 7 Carlos M. Isales, Georgia Regents University, USA Bone Turnover Under Conditions of Caloric Restriction or Selective Nutrient Deprivation
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 2 of 7 Susan B. Racette, Washington University School of Medicine, USA Human Responses to CR: The 'CALERIE' Project
Saturday, April 02 \| 8:00AM - 11:15AM Caloric Restriction and Starvation Room: Jefferson Responses of animals and humans to profound restriction over chronic time scales. Speaker 1 of 7 * Sandra L. Martin, University of Colorado Denver, Anschutz Medical Campus, USA
Saturday, April 02 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Saturday, April 02 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Saturday, April 02 \| 11:15AM - 1:00PM Poster Setup Room: Madison
Saturday, April 02 \| 1:00PM - 10:00PM Poster Viewing Room: Madison
Saturday, April 02 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Saturday, April 02 \| 5:00PM - 7:00PM Over-Nutrition Room: Jefferson Responses of animals and humans to prolonged excess calorie intake. Speaker 5 of 5 Banumathi K. Cole, Eastern Virginia Medical School, USA Short Talk: Nutritional Status Regulates Expression of the Pro-Inflammatory 12/15-Lipoxygenase in Mouse Adipose Tissue
Saturday, April 02 \| 5:00PM - 7:00PM Over-Nutrition Room: Jefferson Responses of animals and humans to prolonged excess calorie intake. Speaker 4 of 5 Donald A. McClain, University of Utah School of Medicine, USA Short Talk: Metabolic Consequences of Genetic Adaptation to High Altitude in Tibetans
Saturday, April 02 \| 5:00PM - 7:00PM Over-Nutrition Room: Jefferson Responses of animals and humans to prolonged excess calorie intake. Speaker 3 of 5 Hongwei Gao, Brigham and Women's Hospital and Harvard Medical School, USA Obesity, Bone Metabolism and Inflammation
Saturday, April 02 \| 5:00PM - 7:00PM Over-Nutrition Room: Jefferson Responses of animals and humans to prolonged excess calorie intake. Speaker 2 of 5 Jan Nedergaard, Stockholm University, Sweden Are we Protected Against Overnutrition?
Saturday, April 02 \| 5:00PM - 7:00PM Over-Nutrition Room: Jefferson Responses of animals and humans to prolonged excess calorie intake. Speaker 1 of 5 * Susan B. Racette, Washington University School of Medicine, USA
Saturday, April 02 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Madison
Saturday, April 02 \| 7:30PM - 10:00PM Poster Session 1 Room: Madison
Sunday, April 03 \| 7:00AM - 8:00AM Breakfast Room: Madison
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 2 of 7 Sandra L. Martin, University of Colorado Denver, Anschutz Medical Campus, USA Poly-Omics of Mammalian Hibernation
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 1 of 7 * John Speakman, Institute of Genetics and Developmental Biology, CAS, China
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 3 of 7 Seth W. Donahue, Michigan Technological University, USA Effects of Hibernation on Bone
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 4 of 7 Kelly L. Drew, University of Alaska, Fairbanks, USA Seasonal Sensitization in Purinergic Signaling Permits Adenosine A1 Receptor Activation to Induce Torpor in Hibernating Arctic Ground Squirrels
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 5 of 7 Matthew T. Andrews, University of Minnesota, USA Molecules Regulating Hibernation in Mammals
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 6 of 7 Hannah V. Carey, University of Wisconsin-Madison, USA Short Talk: Immune Function in Mammalian Hibernation
Sunday, April 03 \| 8:00AM - 11:15AM Hibernation Room: Jefferson Responses of animals to winter that include prolonged torpor and/or body freezing. Speaker 7 of 7 Marshall Hampton, University of Minnesota, Duluth, USA Short Talk: Deep Sequencing the Transcriptome of the 13-Lined Ground Squirrel: An Emerging Model Organism for Mammalian Hibernation
Sunday, April 03 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Sunday, April 03 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Sunday, April 03 \| 1:00PM - 10:00PM Poster Viewing Room: Madison
Sunday, April 03 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Sunday, April 03 \| 5:00PM - 7:00PM Molecular Mediators of Extreme Metabolic States Room: Jefferson Speaker 1 of 5 * Jan Nedergaard, Stockholm University, Sweden
Sunday, April 03 \| 5:00PM - 7:00PM Molecular Mediators of Extreme Metabolic States Room: Jefferson Speaker 2 of 5 Thomas S. Scanlan, Oregon Health & Science University, USA 3-Iodothyronamine: A Novel Bioactive Metabolite of Thyroid Hormone
Sunday, April 03 \| 5:00PM - 7:00PM Molecular Mediators of Extreme Metabolic States Room: Jefferson Speaker 3 of 5 Steven J. Swoap, Williams College, USA AMP vs. Adenosine as a Mediator of Fasting Induced Torpor
Sunday, April 03 \| 5:00PM - 7:00PM Molecular Mediators of Extreme Metabolic States Room: Jefferson Speaker 4 of 5 Mark B. Roth, Fred Hutchinson Cancer Research Center, USA Physiologic Response to Hydrogen Sulfide
Sunday, April 03 \| 5:00PM - 7:00PM Molecular Mediators of Extreme Metabolic States Room: Jefferson Speaker 5 of 5 Kevin J. Phillips, Methodist Hospital Research Institute, USA Short Talk: The Thyroid Hormone Analogue GC-1 Restores Cold Tolerance in Obese (ob/ob) Mice by Rescuing Defects in Adaptive Thermogenesis
Sunday, April 03 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Madison
Sunday, April 03 \| 7:30PM - 10:00PM Poster Session 2 Room: Madison
Monday, April 04 \| 7:00AM - 8:00AM Breakfast Room: Madison
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 1 of 7 * Seth W. Donahue, Michigan Technological University, USA
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 2 of 7 Michael J. Pecaut, Loma Linda University, USA Impact of the Spaceflight Environment on the Immune System
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 3 of 7 Maria-Teresa Giardi, National Council of Research-CNR, Italy Radiation Pressure on D1 Protein Evolution: Space Research and in silico Studies on Chlamydomonas reinhardtii
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 4 of 7 Adrian LeBlanc, USA The Effects of Microgravity on Bone
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 5 of 7 Marco V. Narici, Manchester Metropolitan University, UK Muscle Loss in Space
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 6 of 7 Tulasi R. Jinka, University of Alaska Fairbanks, USA Short Talk: Inhibition of NMDA Type Glutamate Receptors Induces Arousal from Torpor in Hibernating Arctic Ground Squirrels
Monday, April 04 \| 8:00AM - 11:15AM Space Room: Jefferson Responses to space flight and microgravity simulation. Speaker 7 of 7 Scott T. Cooper, University of Wisconsin, La Crosse, USA Short Talk: Effects of Hibernation on Hemostasis and Fibrinolysis in 13-Lined Ground Squirrels Why Blood Clotting in Hibernators is Cool
Monday, April 04 \| 9:20AM - 9:40AM Coffee Break Room: Lower Atrium
Monday, April 04 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Monday, April 04 \| 4:30PM - 5:00PM Coffee Available Room: Lower Atrium
Monday, April 04 \| 5:00PM - 7:00PM Hypoxia Room: Jefferson Speaker 1 of 5 * Kelly L. Drew, University of Alaska, Fairbanks, USA
Monday, April 04 \| 5:00PM - 7:00PM Hypoxia Room: Jefferson Speaker 2 of 5 Vincent Pialoux, Université Claude Bernard Lyon 1, France Hypoxia and Oxidative Stress in Humans: From Physiology to Pathology
Monday, April 04 \| 5:00PM - 7:00PM Hypoxia Room: Jefferson Speaker 3 of 5 Robert S. Mazzeo, University of Colorado, USA Altitude and Immune Function
Monday, April 04 \| 5:00PM - 7:00PM Hypoxia Room: Jefferson Speaker 4 of 5 Zachary A. Cheviron, University of Nebraska, USA Ecological Genomics of High-Altitude Adaptation
Monday, April 04 \| 5:00PM - 7:00PM Hypoxia Room: Jefferson Speaker 5 of 5 Dana L. Miller, University of Washington, USA Short Talk: Hydrogen Sulfide Protects Against Hypoxia in C. elegans
Monday, April 04 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Madison
Monday, April 04 \| 8:00PM - 11:00PM Entertainment Room: Madison
Monday, April 04 \| 8:00PM - 11:00PM Cash Bar Room: Madison
Tuesday, April 05 \| 10:25AM - 10:25AM Departure *Session Chair.