Web Desc
Obesity
joint with Type 2 Diabetes, Insulin Resistance and Metabolic Dysfunction
Organizer(s): Steven R. Smith and Jacqueline M. Stephens
Date: January 12 - 17, 2011
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Takeda Pharmaceutical Company Limited
For important information on the coronavirus, please click here
Summary of Meeting:
An obesity epidemic is sweeping across the Westernized world. More than ever, there is an acknowledgement that the regulation of body weight regulation is more complicated than ever imagined. The last decade has seen rapid progress in our understanding of how body weight is regulated; multiple organs are involved adding to the complexity. These exciting discoveries are leading us in new directions in therapeutics and helping us to better understand of mechanisms underlying the successes of obesity surgery. The goal of this meeting is to bring to light recent advances in the molecular and cellular aspects of these inter-related systems controlling body weight. It is becoming increasingly clear that there are multiple interlocking and redundant systems controlling energy intake, energy expenditure, substrate selection and ultimately body weight. This meeting will assemble international leaders from each of these thematic areas. The program highlights recent advances in the molecular etiology in the major peripheral organs that orchestrate energy balance: adipose tissue, the brain and the gut. Emphasis will be placed on the role of the gut in the regulation of energy metabolism, how the peripheral tissues signal to the brain, and adipose tissue as an orchestrator of metabolism. A major goal of the meeting is to provide a forum that encourages interactions between basic and translational scientists at all career levels to critically evaluate new developments and current controversies. Opportunities for interdisciplinary interactions will be further enhanced by the concurrent meeting on “Diabetes”, which will share two Keynote Speakers and three joint plenary sessions with this meeting. The joint sessions will cover mitochondrial energetics, how adipose tissue causes insulin resistance and the epigenetic control of metabolism concluding with a workshop / panel discussion on mechanisms of insulin resistance in obesity.
Scholarship Deadline: September 17 2010
Discounted Abstract Deadline: September 17 2010
Abstract Deadline: October 15 2010
Discounted Registration Deadline: November 12 2010
We gratefully acknowledge additional support for this conference from:
AdipoGen InternationalTakeda Pharmaceutical Company Limited
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-02
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Wednesday, January 12 | 3:00PM - 7:30PM
Registration
Room: Longs Peak Foyer


Wednesday, January 12 | 6:15PM - 7:15PM
Refreshments
Room: Longs Peak Foyer


Wednesday, January 12 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Columbine Ballroom

Speaker 1 of 4
* Deborah M. Muoio, Duke University Medical Center, USA

Wednesday, January 12 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Columbine Ballroom

Speaker 2 of 4
* Steven R. Smith, AdventHealth, USA

Wednesday, January 12 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Columbine Ballroom

Speaker 3 of 4
Stephen O'Rahilly, University of Cambridge, UK
Common Metabolic Disorders: Lessons from Human Genetics

Wednesday, January 12 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Columbine Ballroom

Speaker 4 of 4
David A. Sinclair, Harvard Medical School, USA
Genetic and Pharmacological Interventions to Treat Age-Related Diseases

Thursday, January 13 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Thursday, January 13 | 8:00AM - 11:00AM
Mitochondrial Bioenergetics in Health and Disease (Joint)
Room: Columbine Ballroom

Speaker 1 of 6
* P. Darrell Neufer, East Carolina University, USA

Thursday, January 13 | 8:00AM - 11:00AM
Mitochondrial Bioenergetics in Health and Disease (Joint)
Room: Columbine Ballroom

Speaker 2 of 6
Daniel P. Kelly, University of Pennsylvania, USA
Networks Controlling Muscle Mitochondrial Function

Thursday, January 13 | 8:00AM - 11:00AM
Mitochondrial Bioenergetics in Health and Disease (Joint)
Room: Columbine Ballroom

Speaker 3 of 6
Mary-Ellen Harper, University of Ottawa, Canada
Mitochondrial Uncoupling: Energy Costs and ROS Control Benefits

Thursday, January 13 | 8:00AM - 11:00AM
Mitochondrial Bioenergetics in Health and Disease (Joint)
Room: Columbine Ballroom

Speaker 4 of 6
Xianwen Yi, University of North Carolina, USA
Short Talk: Does Alpha-Lipoic Acid Retain Body Energy by Regulating Nitric Oxide and Reversing Mitochondrial Dysfunction?

Thursday, January 13 | 8:00AM - 11:00AM
Mitochondrial Bioenergetics in Health and Disease (Joint)
Room: Columbine Ballroom

Speaker 5 of 6
Iain Scott, University of Pittsburgh, USA
Short Talk: A Prokaryote-Derived Mitochondrial Acetyltransferase Counteracts the Respiratory Effects of SIRT3

Thursday, January 13 | 8:00AM - 11:00AM
Mitochondrial Bioenergetics in Health and Disease (Joint)
Room: Columbine Ballroom

Speaker 6 of 6
Bruce M. Spiegelman, Harvard Medical School, USA
Transcriptional Regulation of Adipogenesis and Energy Homeostasis

Thursday, January 13 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, January 13 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Thursday, January 13 | 11:15AM - 12:00PM
NIH Sponsored Workshop: NIH Loan-Repayment Program (Joint)
Room: Columbine Ballroom

Speaker 1 of 1
Milton Hernandez, NIAID, National Institutes of Health, USA

Thursday, January 13 | 11:15AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Thursday, January 13 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 1 of 7
* Antonio J. Vidal-Puig, University of Cambridge, UK

Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 2 of 7
Parth Patwari, Brigham and Women's Hospital, USA
The Alpha-Arrestin ARRDC3 Regulates Obesity in Mice and Humans

Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 3 of 7
Shwetha Ramachandrappa, Cambridge University, UK
Single Minded 1 (SIM1) in Severe Early Onset Obesity

Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 4 of 7
Peter K. Jackson, Stanford University, USA
Ciliopathies and Monogenic Obesity Disorders: Bardet-Biedl Syndrome (BBS) and Tubby Family Proteins Direct GPCR Traffic to the Primary Cilium

Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 5 of 7
Clemence Blouet, University of Cambridge, UK
Nutrient Sensing Hypothalamic TXNIP Links Nutrient Excess to Energy Imbalance in Mice

Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 6 of 7
Nicole Ehrhardt, Cedars-Sinai Medical Center, USA
Lmf1 Deficiency Causes Lipodystrophy

Thursday, January 13 | 2:30PM - 4:30PM
Workshop 1: Hot Topics in Obesity Mechanisms
Room: Quandry Peak

Speaker 7 of 7
Rebecca E. Mercer, University of Alberta, Canada
Leptin Resistance in the Magel2-null Mouse Model of Prader-Willi Syndrome Precedes the Development of Obesity and is Associated with Increased Melanocortin Responsiveness

Thursday, January 13 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, January 13 | 5:00PM - 7:00PM
The Adipose-Brain Axis
Room: Quandary Peak

Speaker 1 of 3
* Karine Clément, INSERM / Sorbonne Universite, France

Thursday, January 13 | 5:00PM - 7:00PM
The Adipose-Brain Axis
Room: Quandary Peak

Speaker 2 of 3
Randy J. Seeley, University of Michigan, USA
A Role for CNS PPARgamma in the Regulation of Energy Balance

Thursday, January 13 | 5:00PM - 7:00PM
The Adipose-Brain Axis
Room: Quandary Peak

Speaker 3 of 3
Steven R. Smith, AdventHealth, USA
Adipose Tissue Hypoxia in Obesity

Thursday, January 13 | 5:00PM - 7:00PM
Sirtuins, NAD Biology and Circadian Control of Metabolism
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 1 of 5
* David A. Sinclair, Harvard Medical School, USA


Thursday, January 13 | 5:00PM - 7:00PM
Sirtuins, NAD Biology and Circadian Control of Metabolism
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 2 of 5
Shin-ichiro Imai, Washington University School of Medicine, USA
SIRT1 and NAMPT-Mediated NAD Biosynthesis: Systemic Control of Metabolism and Aging in Mammals


Thursday, January 13 | 5:00PM - 7:00PM
Sirtuins, NAD Biology and Circadian Control of Metabolism
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 3 of 5
Matthew D. Hirschey, Duke University, USA
Short Talk: SIRT3 Deficiency Accelerates the Development of the Metabolic Syndrome


Thursday, January 13 | 5:00PM - 7:00PM
Sirtuins, NAD Biology and Circadian Control of Metabolism
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 4 of 5
Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA
Epigenomic Regulation of Circadian Rhythm and Metabolism by Nuclear Receptors


Thursday, January 13 | 5:00PM - 7:00PM
Sirtuins, NAD Biology and Circadian Control of Metabolism
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 5 of 5
Ueli Schibler, University of Geneva, Switzerland
The Synchronization of Peripheral Circadian Clocks


Thursday, January 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom


Thursday, January 13 | 7:30PM - 10:00PM
Poster Session 1
Room: Colorado Rockies Ballroom


Friday, January 14 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Friday, January 14 | 8:00AM - 11:00AM
Gut Nutrient Sensing in the Regulation of Body Weight
Room: Quandary Peak

Speaker 1 of 6
* Randy J. Seeley, University of Michigan, USA

Friday, January 14 | 8:00AM - 11:00AM
Gut Nutrient Sensing in the Regulation of Body Weight
Room: Quandary Peak

Speaker 2 of 6
Elaine Holmes, Imperial College London, UK
The Gut Microbiome in Obesity

Friday, January 14 | 8:00AM - 11:00AM
Gut Nutrient Sensing in the Regulation of Body Weight
Room: Quandary Peak

Speaker 3 of 6
Philip Schauer, Cleveland Clinic Foundation, USA
Obesity Surgery: State-of-the-Art?

Friday, January 14 | 8:00AM - 11:00AM
Gut Nutrient Sensing in the Regulation of Body Weight
Room: Quandary Peak

Speaker 4 of 6
Robert F. Margolskee, Monell Chemical Senses Center, USA
Taste Receptors in Gut Regulate Endocrine Function

Friday, January 14 | 8:00AM - 11:00AM
Gut Nutrient Sensing in the Regulation of Body Weight
Room: Quandary Peak

Speaker 5 of 6
Vincent Aguirre, University of Texas, Southwestern Medical Center, USA
Short Talk: MC4Rs in Autonomic Neurons of the Brainstem Mediate Effects of Gastric Bypass on Diabetes but not Energy Expenditure or Body Weight

Friday, January 14 | 8:00AM - 11:00AM
Gut Nutrient Sensing in the Regulation of Body Weight
Room: Quandary Peak

Speaker 6 of 6
Hua V. Lin, Forkhead BioTherapeutics Inc, USA
Short Talk: Short-Chain Fatty Acids Regulate Incretin Secretion & Energy Metabolism and Protect Against Diet Induced Obesity

Friday, January 14 | 8:00AM - 11:15AM
Insulin Resistance, Mitochondrial Dysfunction and Lipotoxici
ty in Humans
This session is from Diabetes

Room: Longs/Grays Peak

Speaker 1 of 6
* Mary-Elizabeth Patti, Joslin Diabetes Center, USA


Friday, January 14 | 8:00AM - 11:15AM
Insulin Resistance, Mitochondrial Dysfunction and Lipotoxici
ty in Humans
This session is from Diabetes

Room: Longs/Grays Peak

Speaker 2 of 6
Christoph Handschin, University of Basel, Switzerland
Coordination of Anabolic and Catabolic Pathways in Skeletal Muscle by PGC1Ą


Friday, January 14 | 8:00AM - 11:15AM
Insulin Resistance, Mitochondrial Dysfunction and Lipotoxici
ty in Humans
This session is from Diabetes

Room: Longs/Grays Peak

Speaker 3 of 6
K. Sreekumaran Nair, Mayo Clinic, USA
Muscle Mitochondrial Dysfunction and Muscle Insulin Resistance in Diabetes


Friday, January 14 | 8:00AM - 11:15AM
Insulin Resistance, Mitochondrial Dysfunction and Lipotoxici
ty in Humans
This session is from Diabetes

Room: Longs/Grays Peak

Speaker 4 of 6
P. Darrell Neufer, East Carolina University, USA
Mitochondrial Bioenergetics, Redox Imbalance and Insulin Resistance


Friday, January 14 | 8:00AM - 11:15AM
Insulin Resistance, Mitochondrial Dysfunction and Lipotoxici
ty in Humans
This session is from Diabetes

Room: Longs/Grays Peak

Speaker 5 of 6
Elizabeth J. Parks, University of Missouri, USA
Alterations in Fatty Acid Partitioning during Feeding


Friday, January 14 | 8:00AM - 11:15AM
Insulin Resistance, Mitochondrial Dysfunction and Lipotoxici
ty in Humans
This session is from Diabetes

Room: Longs/Grays Peak

Speaker 6 of 6
C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Novel Actions of Insulin in Control of Brain and Body Metabolism


Friday, January 14 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Friday, January 14 | 11:00AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Friday, January 14 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Friday, January 14 | 1:00PM - 1:00PM
On Own for Lunch and Recreation


Friday, January 14 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Friday, January 14 | 5:00PM - 7:00PM
How Adipose Tissue Causes Insulin Resistance (Joint)
Room: Columbine Ballroom

Speaker 1 of 4
Anthony W. Ferrante, Columbia University, USA
Immunology and Metabolism in Adipose Tissue

Friday, January 14 | 5:00PM - 7:00PM
How Adipose Tissue Causes Insulin Resistance (Joint)
Room: Columbine Ballroom

Speaker 2 of 4
Karine Clément, INSERM / Sorbonne Universite, France
Human Adipose Tissue Remodelling and Metabolic Complications

Friday, January 14 | 5:00PM - 7:00PM
How Adipose Tissue Causes Insulin Resistance (Joint)
Room: Columbine Ballroom

Speaker 3 of 4
Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Adipose Tissue Factors: Modulators of Insulin Sensitivity, Inflammation and Apoptosis

Friday, January 14 | 5:00PM - 7:00PM
How Adipose Tissue Causes Insulin Resistance (Joint)
Room: Columbine Ballroom

Speaker 4 of 4
Timo D. Müller, Institute for Diabetes and Obesity, Germany
Short Talk: Sequestosome 1 (P62) Deficiency in Adipose Tissue Leads to Obesity and Glucose Intolerance by Impairing BAT Function in Mice

Friday, January 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom


Friday, January 14 | 7:30PM - 10:00PM
Poster Session 2
Room: Colorado Rockies Ballroom


Saturday, January 15 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Saturday, January 15 | 8:00AM - 11:15AM
Adipose Tissue Architecture
Room: Quandary Peak

Speaker 1 of 6
* Jacqueline M. Stephens, Louisiana State University, USA

Saturday, January 15 | 8:00AM - 11:15AM
Adipose Tissue Architecture
Room: Quandary Peak

Speaker 2 of 6
James G. Granneman, Wayne State University School of Medicine, USA
Imaging the Organization and Trafficking of Lipolytic Proteins

Saturday, January 15 | 8:00AM - 11:15AM
Adipose Tissue Architecture
Room: Quandary Peak

Speaker 3 of 6
David E. James, University of Sydney, Australia
Mapping the Insulin Signalling Network in Adipocytes

Saturday, January 15 | 8:00AM - 11:15AM
Adipose Tissue Architecture
Room: Quandary Peak

Speaker 4 of 6
Matthew J. Brady, University of Chicago, USA
Stranger in a Strange Land: Glycogen Metabolism in Adipose Tissue

Saturday, January 15 | 8:00AM - 11:15AM
Adipose Tissue Architecture
Room: Quandary Peak

Speaker 5 of 6
Justin J. Rochford, University of Aberdeen, UK
Short Talk: The Human Lipodystrophy Protein BSCL2/Seipin Binds the Key Lipogenic Enzyme Lipin 1

Saturday, January 15 | 8:00AM - 11:15AM
Adipose Tissue Architecture
Room: Quandary Peak

Speaker 6 of 6
Xunshan Ding, University of Texas Southwestern Medical Center, USA
Short Talk: beta-Klotho in Adipose Tissue Is Required for the Anti-Obesity Effect of Fibroblast Growth Factor 21 in Mice

Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 1 of 7
* Rosalind A. Coleman, University of North Carolina at Chapel Hill, USA


Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 2 of 7
David A. Bernlohr, University of Minnesota, USA
Oxidative Stress and Adipocyte Mitochondrial Dysfunction


Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 3 of 7
Seung-Hoi Koo, Korea University, South Korea
Regulation of Hepatic Glucose Output by TORC2/CRTC2


Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 4 of 7
Roberta Leonardi, West Virginia University, USA
Short Talk: Gluconeogenesis is Controlled by CoA Levels and PanK1


Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 5 of 7
Reuben J. Shaw, The Salk Institute for Biological Studies, USA
Class IIa Histone Deacetylases are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis


Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 6 of 7
Deborah M. Muoio, Duke University Medical Center, USA
Mitochondrial Stress and Metabolic Dysfunction in Skeletal Muscle


Saturday, January 15 | 8:00AM - 11:00AM
Mechanisms of Metabolic Failure
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 7 of 7
Romain Barres, NNF Center for Basic Metabolic Research, Denmark
Short Talk: Exercise Induces Transient DNA Hypomethylation in Human Skeletal Muscle


Saturday, January 15 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Saturday, January 15 | 11:15AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Saturday, January 15 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Saturday, January 15 | 1:00PM - 1:00PM
On Own for Lunch and Recreation


Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 1 of 8
Chenguang Ouyang, Indiana University, USA
Discovery of Peptides Balanced In Glucagon Receptor Antagonism and GLP-1 Agonism. A Search for the Molecular Basis in the Inversion of Activity at Homologous Receptors

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 2 of 8
* Thomas E. Hughes, Zafgen, Inc, USA
Methionine Aminopeptidase 2 (MetAP2) Inhibition Improves Metabolic Control and Causes Loss of Excess Body Weight in Mice, Dogs, and Humans

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 3 of 8
Shirly Pinto, Kallyope, USA
Pharmacological Inhibition of Diacylglycerol Acyltransferase 1 Leads to Weight Loss and Prolongation of GLP-1 Release

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 4 of 8
* Claire M. Steppan, Pfizer, USA
Pharmacological Inhibition to Examine the Role of DGAT1 in Dietary Lipid Absorption in Mice and Man

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 5 of 8
Jennifer L. Lachey, Ember Therapeutics, USA
Characterization of the Thermogenic Program Induced in White Adipose Tissue of HFD-Fed Mice Treated with a Soluble ActRIIB

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 6 of 8
Yong Qi, Sirtris, A GlaxoSmithKline Company, USA
Activation of Sirtuin1 (SIRT1) by the Novel Small Molecule SRT2104 Protects against Diet-Induced Obesity and Improves Glucose Homeostasis by Increasing Fatty Acid and Carbohydrate Oxidation in Mice

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 7 of 8
Andrea R. Nawrocki, Janssen Pharmaceutical, USA
The Metabotropic Glutamate Receptor mGluR8 Modulates Energy Metabolism and Amphetamine Induced Hyperactivity in Mice

Saturday, January 15 | 2:30PM - 4:30PM
Workshop 2: Hot Topics in Obesity Therapy
Room: Quandary Peak

Speaker 8 of 8
Matthias H. Tschöp, Helmholtz Zentrum München and Technische Universität München, Germany
Enhanced Metabolic Benefits of Single Peptides with Nuclear Hormone Pharmacology

Saturday, January 15 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Saturday, January 15 | 5:00PM - 7:00PM
JAK-STAT Signaling in Obesity
Room: Quandary Peak

Speaker 1 of 5
* Stephen R. Farmer, Boston University School of Medicine, USA

Saturday, January 15 | 5:00PM - 7:00PM
JAK-STAT Signaling in Obesity
Room: Quandary Peak

Speaker 2 of 5
Jacqueline M. Stephens, Louisiana State University, USA
STATs in Adipocyte Development and Function

Saturday, January 15 | 5:00PM - 7:00PM
JAK-STAT Signaling in Obesity
Room: Quandary Peak

Speaker 3 of 5
Martin G. Myers, Jr., University of Michigan, USA
Molecular and Neural Mechanisms of Leptin Action

Saturday, January 15 | 5:00PM - 7:00PM
JAK-STAT Signaling in Obesity
Room: Quandary Peak

Speaker 4 of 5
Allison W. Xu, University of California, San Francisco, USA
Regulation of Energy Balance and Hepatic Lipid Metabolism by Central Stat3 and PI3K Signaling

Saturday, January 15 | 5:00PM - 7:00PM
JAK-STAT Signaling in Obesity
Room: Quandary Peak

Speaker 5 of 5
Tamara L. Allen, Baker IDI Heart and Diabetes Institute, Australia
Short Talk: Modified IC7, a Designer gp130 Receptor Ligand that improves obesity, Improves High Fat Diet-Induced Insulin Resistance

Saturday, January 15 | 5:00PM - 7:00PM
Lipid Trafficking and Signaling
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 1 of 5
* David A. Bernlohr, University of Minnesota, USA


Saturday, January 15 | 5:00PM - 7:00PM
Lipid Trafficking and Signaling
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 2 of 5
Rosalind A. Coleman, University of North Carolina at Chapel Hill, USA
ACSL1 and Lipid Partitioning


Saturday, January 15 | 5:00PM - 7:00PM
Lipid Trafficking and Signaling
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 3 of 5
Rudolf Zechner, University of Graz, Austria
Lipolysis and the Lipid Droplet Signaling to the PPARs/PGC1á


Saturday, January 15 | 5:00PM - 7:00PM
Lipid Trafficking and Signaling
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 4 of 5
Hei Sook Sul, University of California, Berkeley, USA
Regulation of Adipocyte Lipolysis


Saturday, January 15 | 5:00PM - 7:00PM
Lipid Trafficking and Signaling
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 5 of 5
Saswata Talukdar, Merck Sharp & Dohme, USA
Short Talk: GPR120 is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-Inflammatory and Insulin Sensitizing Effects


Saturday, January 15 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom


Saturday, January 15 | 7:30PM - 10:00PM
Poster Session 3
Room: Colorado Rockies Ballroom


Sunday, January 16 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Sunday, January 16 | 7:30AM - 8:00AM
Poster Setup
Room: Colorado Rockies Ballroom


Sunday, January 16 | 8:00AM - 5:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 1 of 7
* Matthew J. Brady, University of Chicago, USA

Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 2 of 7
Antonio J. Vidal-Puig, University of Cambridge, UK
Allostatic Load and Over-Load in the Context of PPARgamma Ablation

Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 3 of 7
Evan D. Rosen, Harvard University, USA
Comparative Epigenomic Analysis of Human and Murine Adipogenesis

Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 4 of 7
Stephen R. Farmer, Boston University School of Medicine, USA
Repression of Gene Programs during the Conversion of Mesenchymal Stem Cells to Adipocytes

Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 5 of 7
Merlin Crossley, University of New South Wales, Australia
The Transcriptional Regulators: KLF3, C-Terminal Binding Protein Co-Repressor (Ctbp), and Friend of Gata in the Regulation of Adipogenesis

Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 6 of 7
Kai Ge, NIDDK, National Institutes of Health, USA
Short Talk: Epigenetic Regulation of Adipogenesis by Histone Methylation

Sunday, January 16 | 8:00AM - 11:15AM
New Players in the Old Game - Adipogenesis
Room: Quandary Peak

Speaker 7 of 7
Juliane G. Bogner-Strauss, Graz University of Technology, Austria
Short Talk: Adipocyte Plasma Membrane-Associated Protein (APMAP): A Transmembrane Protein Required for Adipogenesis and Targeted by PPARgamma

Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 1 of 8
* Elizabeth J. Parks, University of Missouri, USA


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 2 of 8
Laurie J. Goodyear, Joslin Diabetes Center, Harvard Medical School, USA
Exercise-Induced Enhancement of Insulin Action


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 3 of 8
Jorge L. Ruas, Karolinska Institutet, Sweden
Short Talk: Hypertrophic Effects of the PGC1a4 Isoform on Skeletal Muscle


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 4 of 8
* Christopher B. Newgard, Duke University Medical Center, USA
In Search of Targets for Restoring beta-Cell Function in Diabetes


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 5 of 8
Angela M. Hall, Washington University School of Medicine, USA
Short Talk: Suppression of Monoacylglycerol Acyltransferase-1 (Mogat1) Improves Glucose Tolerance in Diet-Induced Obese Mice


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 6 of 8
Andrew Butler, St. Louis University, USA
Short Talk: Adropin-Deficient Mice Exhibit a Pre-Diabetic Condition and Increased Metabolic Distress with Diet-Induced Obesity


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 7 of 8
Vijay K. Yechoor, University of Pittsburgh, USA
Short Talk: Bmal1 and beta-Cell Clock are Required for Mitochondrial Function and GSIS


Sunday, January 16 | 8:00AM - 11:15AM
Insulin Signaling, Action and Secretion
This session is from Diabetes
Room: Longs/Grays Peak

Speaker 8 of 8
Markus Stoffel, ETH Zürich, Switzerland
MicroRNAs and Regulation of Glucose and Lipid Metabolism


Sunday, January 16 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Sunday, January 16 | 11:15AM - 12:15PM
Lunch


Sunday, January 16 | 12:00PM - 2:30PM
Poster Session 4
Room: Colorado Rockies Ballroom


Sunday, January 16 | 2:30PM - 4:30PM
Workshop: Mechanisms of Insulin Resistance: Recent Advances
and Current Controversies (Joint)
Room: Columbine Ballroom

Speaker 1 of 6
* Christopher B. Newgard, Duke University Medical Center, USA

Sunday, January 16 | 2:30PM - 4:30PM
Workshop: Mechanisms of Insulin Resistance: Recent Advances
and Current Controversies (Joint)
Room: Columbine Ballroom

Speaker 2 of 6
Deborah M. Muoio, Duke University Medical Center, USA

Sunday, January 16 | 2:30PM - 4:30PM
Workshop: Mechanisms of Insulin Resistance: Recent Advances
and Current Controversies (Joint)
Room: Columbine Ballroom

Speaker 3 of 6
Philipp E. Scherer, University of Texas Southwestern Medical Center, USA

Sunday, January 16 | 2:30PM - 4:30PM
Workshop: Mechanisms of Insulin Resistance: Recent Advances
and Current Controversies (Joint)
Room: Columbine Ballroom

Speaker 4 of 6
Laurie J. Goodyear, Joslin Diabetes Center, Harvard Medical School, USA

Sunday, January 16 | 2:30PM - 4:30PM
Workshop: Mechanisms of Insulin Resistance: Recent Advances
and Current Controversies (Joint)
Room: Columbine Ballroom

Speaker 5 of 6
Rosalind A. Coleman, University of North Carolina at Chapel Hill, USA

Sunday, January 16 | 2:30PM - 4:30PM
Workshop: Mechanisms of Insulin Resistance: Recent Advances
and Current Controversies (Joint)
Room: Columbine Ballroom

Speaker 6 of 6
P. Darrell Neufer, East Carolina University, USA

Sunday, January 16 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Sunday, January 16 | 5:00PM - 7:00PM
Epigenetic Control of Metabolism (Joint)
Room: Columbine Ballroom

Speaker 1 of 4
* Steven R. Smith, AdventHealth, USA

Sunday, January 16 | 5:00PM - 7:00PM
Epigenetic Control of Metabolism (Joint)
Room: Columbine Ballroom

Speaker 2 of 4
Mary-Elizabeth Patti, Joslin Diabetes Center, USA
Developmental Origins of Obesity and Type 2 Diabetes

Sunday, January 16 | 5:00PM - 7:00PM
Epigenetic Control of Metabolism (Joint)
Room: Columbine Ballroom

Speaker 3 of 4
Kevin L. Grove, Novo Nordisk, USA
Programming Metabolic Disease: Effects of Maternal Obesity and Diet

Sunday, January 16 | 5:00PM - 7:00PM
Epigenetic Control of Metabolism (Joint)
Room: Columbine Ballroom

Speaker 4 of 4
Andrew P. Feinberg, Johns Hopkins University School of Medicine, USA
The Epigenetic Basis of Common Human Disease

Sunday, January 16 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom


Sunday, January 16 | 8:00PM - 11:00PM
Entertainment
Room: Colorado Rockies Ballroom


Sunday, January 16 | 8:00PM - 11:00PM
Cash Bar
Room: Colorado Rockies Ballroom


Monday, January 17 | 10:22AM - 10:22AM
Departure


*Session Chair
†Invited, not yet responded.