Web Desc
Molecular Cardiology: Disease Mechanisms and Experimental Therapeutics
joint with Mechanisms of Cardiac Growth, Death and Regeneration
Organizer(s): Joseph M. Metzger, Leslie A. Leinwand and Jeffery D. Molkentin
Date: February 22 - 27, 2011
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Bayer USA Foundation
Summary of Meeting:
Human health and wellness are advanced, both nationally and globally, by new mechanistic insights emanating from the field of molecular cardiology and its application to experimental cardiovascular therapeutics. This meeting is designed to attract leading laboratories, investigators, students and trainees in the field to address gaps in fundamental pathways in human heart functionality and how, when they become dysfunctional, they contribute to cardiac disease. The significance and impact of this meeting is further amplified by aligning in joint format with the parallel Keystone Symposia meeting on Mechanisms of Cardiac Growth, Death and Regeneration. Collectively, these meetings will address the fundamental mechanisms that regulate cardiac structure, function, and repair and how they relate to human heart disease. Another unique feature of this joint meeting stems from implementing and highlighting an Early Independent Career Research Competition and a dedicated Graduate Student and Postdoc Research Competition. Specific Objectives feature: 1) insights and controversies in the genetics, epigenetics and the biochemistry and physiology of cardiac cell growth; 2) emerging concepts in cardiac calcium handling and how new mechanistic insights are informing novel experimental therapeutics; and 3) mechanisms of inter- and intra-cellular cardiac communication in health and disease. The concurrent meeting format also aims to accomplish the following: 4) stimulate interactions among stem cell biologists and individuals studying cardiac growth, death and cardiac physiology; and 5) provide trainees with a significant learning experience through several mechanisms in addition to the usual lectures and poster presentations.
Scholarship Deadline: October 21 2010
Discounted Abstract Deadline: October 21 2010
Abstract Deadline: November 23 2010
Discounted Registration Deadline: December 22 2010
We gratefully acknowledge additional support for this conference from:
American Heart AssociationBayer USA Foundation
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1R13HL106856-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, February 22 | 3:00PM - 7:30PM
Registration
Room: Longs Peak Foyer


Tuesday, February 22 | 6:15PM - 7:15PM
Refreshments
Room: Longs Peak Foyer


Tuesday, February 22 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Longs/Grays Peak

Speaker 1 of 4
* Richard N. Kitsis, Albert Einstein College of Medicine, USA

Tuesday, February 22 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Longs/Grays Peak

Speaker 2 of 4
* Joseph M. Metzger, University of Minnesota Medical School, USA

Tuesday, February 22 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Longs/Grays Peak

Speaker 3 of 4
Joanna Wysocka, Stanford University, USA
Chromatin, Enhancers and Emergence of Epigenomes in Development

Tuesday, February 22 | 7:15PM - 9:30PM
Welcome and Keynote Session (Joint)
Room: Longs/Grays Peak

Speaker 4 of 4
Robert J. Lefkowitz, HHMI/Duke University Medical Center, USA
Pleiotropic Signaling from G Protein-Coupled Receptors

Wednesday, February 23 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Wednesday, February 23 | 8:00AM - 11:00AM
Genetic and Epigenetic Specification of Cardiac Structure an
d Function (Joint)

Room: Longs/Grays Peak

Speaker 1 of 6
* Jeffrey Robbins, Cincinnati Children's Hospital Medical Center, USA

Wednesday, February 23 | 8:00AM - 11:00AM
Genetic and Epigenetic Specification of Cardiac Structure an
d Function (Joint)

Room: Longs/Grays Peak

Speaker 2 of 6
Christine E. Seidman, Harvard Medical School, USA
Finding Missing Mutations in DCM

Wednesday, February 23 | 8:00AM - 11:00AM
Genetic and Epigenetic Specification of Cardiac Structure an
d Function (Joint)

Room: Longs/Grays Peak

Speaker 3 of 6
Elizabeth M. McNally, Northwestern University, USA
Genetic Modifiers for Heart and Muscle Disease

Wednesday, February 23 | 8:00AM - 11:00AM
Genetic and Epigenetic Specification of Cardiac Structure an
d Function (Joint)

Room: Longs/Grays Peak

Speaker 4 of 6
Stuart Cook, Duke-NUS, Singapore
Systems Genetics Studies of Heart Disease

Wednesday, February 23 | 8:00AM - 11:00AM
Genetic and Epigenetic Specification of Cardiac Structure an
d Function (Joint)

Room: Longs/Grays Peak

Speaker 5 of 6
Jean E. Schaffer, Joslin Diabetes Center, Harvard Medical School, USA
Unexpected Regulators of Metabolic Stress

Wednesday, February 23 | 8:00AM - 11:00AM
Genetic and Epigenetic Specification of Cardiac Structure an
d Function (Joint)

Room: Longs/Grays Peak

Speaker 6 of 6
Roger Foo, Genome Institute of Singapore, Singapore
Short Talk: Distinct Epigenomic Features of Human Heart Failure

Wednesday, February 23 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, February 23 | 11:00AM - 1:00PM
Poster Setup
Room: Quandary Peak


Wednesday, February 23 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Wednesday, February 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary Peak


Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 1 of 9
* Ivor J. Benjamin, University of Utah, USA

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 2 of 9
* Leslie A. Leinwand, University of Colorado Boulder, USA

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 3 of 9
* Richard N. Kitsis, Albert Einstein College of Medicine, USA

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 4 of 9
* Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 5 of 9
* Charles E. Murry, University of Washington, USA

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 6 of 9
Ching-Pin Chang, Indiana University, USA
Chromatin Remodeling by Brg1 Regulates Cardiac Growth, Differentiation and Hypertrophy

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 7 of 9
Maria I. Kontaridis, Beth Israel Deaconess Medical Center, USA
Rapamycin Normalizes Hypertrophic Cardiomyopathy in a Mouse Model of LEOPARD Syndrome-Associated PTPN11 Mutation

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 8 of 9
Sharlene M. Day, University of Pennsylvania, USA
Disrupted Sarcomere Stoichiometry and Heterogeneous Expression of Mutant Sarcomere Proteins in Human Hypertrophic Cardiomyopathy

Wednesday, February 23 | 3:30PM - 4:30PM
Workshop 1: Early Independent Career Research Competition (J
oint)
Room: Longs/Grays Peak
The Early Independent Career Research Competition will be for independent faculty (Independent Junior Research Faculty/Assistant Professors (not tenured)). There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions. The referees will select a winner from the presenters. The winners from the two competitions will be announced on the final night of the meeting.
Speaker 9 of 9
Zoltan P. Arany, University of Pennsylvania, USA
PGC-1alpha Regulates Cardiac Vascularity and Protects from Post-Partum Cardiomyopathy

Wednesday, February 23 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, February 23 | 5:00PM - 7:00PM
Regulation of Cardiac Function
Room: Longs Peak

Speaker 1 of 5
* Eric N. Olson, University of Texas Southwestern Medical Center, USA

Wednesday, February 23 | 5:00PM - 7:00PM
Regulation of Cardiac Function
Room: Longs Peak

Speaker 2 of 5
Howard A. Rockman, Duke University Medical Center, USA
Beta-Arrestin Signaling and Cardiac Function

Wednesday, February 23 | 5:00PM - 7:00PM
Regulation of Cardiac Function
Room: Longs Peak

Speaker 3 of 5
Walter J. Koch, Temple University School of Medicine, USA
Novel Roles of GRKs in Cardiac Injury and Repair

Wednesday, February 23 | 5:00PM - 7:00PM
Regulation of Cardiac Function
Room: Longs Peak

Speaker 4 of 5
David A. Kass, Johns Hopkins Hospital, USA
Cyclic GMP/PKG Modulation of Heart Disease

Wednesday, February 23 | 5:00PM - 7:00PM
Regulation of Cardiac Function
Room: Longs Peak

Speaker 5 of 5
Ralph Knöll, AstraZeneca and Karolinska Institutet, Sweden
Short Talk: Novel MLP-Interacting Proteins and Their Potential Role in Cardiomyopathy

Wednesday, February 23 | 5:00PM - 7:00PM
Cardiac Stress Responses
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 1 of 5
* Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA


Wednesday, February 23 | 5:00PM - 7:00PM
Cardiac Stress Responses
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 2 of 5
Jeffrey Robbins, Cincinnati Children's Hospital Medical Center, USA
Choices of a Stressed Cardiomyocyte: Necrosis, Apoptosis or Autophagy?


Wednesday, February 23 | 5:00PM - 7:00PM
Cardiac Stress Responses
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 3 of 5
Ivor J. Benjamin, University of Utah, USA
Mammalian HSP-HSF Regulatory Network For Pretein Quality Control


Wednesday, February 23 | 5:00PM - 7:00PM
Cardiac Stress Responses
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 4 of 5
Issei Komuro, Tokyo University Graduate School, Japan
p53 as a Mediator of Cardiovascular Diseases


Wednesday, February 23 | 5:00PM - 7:00PM
Cardiac Stress Responses
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 5 of 5
Jill Rafael-Fortney, Ohio State University College of Medicine, USA
Short Talk: Claudin-5 Prevents Functional and Histological Indicators of Cardiomyopathy, and Represents a Novel Treatment Strategy for Heart Failure


Wednesday, February 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Wednesday, February 23 | 7:30PM - 10:00PM
Poster Session 1
Room: Quandary Peak


Thursday, February 24 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Thursday, February 24 | 8:00AM - 11:00AM
New Insights into Cardiac Hypertrophy
Room: Longs Peak

Speaker 1 of 6
* Howard A. Rockman, Duke University Medical Center, USA

Thursday, February 24 | 8:00AM - 11:00AM
New Insights into Cardiac Hypertrophy
Room: Longs Peak

Speaker 2 of 6
Anthony Rosenzweig, Massachusetts General Hospital, USA
SGK1 in Pathological Cardiac Hypertrophy, Failure, and Arrhythmias

Thursday, February 24 | 8:00AM - 11:00AM
New Insights into Cardiac Hypertrophy
Room: Longs Peak

Speaker 3 of 6
Meredith Bond, University of Maryland School of Medicine, USA
AKAPs in Healthy and Failing Heart

Thursday, February 24 | 8:00AM - 11:00AM
New Insights into Cardiac Hypertrophy
Room: Longs Peak

Speaker 4 of 6
Eric N. Olson, University of Texas Southwestern Medical Center, USA
MicroRNA Control of Cardiovascular Development and Disease

Thursday, February 24 | 8:00AM - 11:00AM
New Insights into Cardiac Hypertrophy
Room: Longs Peak

Speaker 5 of 6
Joan Heller Heller Brown, University of California, San Diego, USA
Ca++/calmodulin-Dependent Protein Kinase II in Heart Failure Development

Thursday, February 24 | 8:00AM - 11:00AM
New Insights into Cardiac Hypertrophy
Room: Longs Peak

Speaker 6 of 6
Zhi-Ping Liu, University of Texas Southwestern Medical Center, USA
Short Talk: The Histone Trimethyl Demethylase, JMJD2A, Promotes Pressure Overload-Induced Cardiac Hypertrophy

Thursday, February 24 | 8:00AM - 11:00AM
Directed Differentiation of Cardiac Progenitors
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 1 of 6
* Gordon M. Keller, University Health Network, MaRS Centre, Canada


Thursday, February 24 | 8:00AM - 11:00AM
Directed Differentiation of Cardiac Progenitors
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 2 of 6
Deepak Srivastava, Gladstone Institutes, USA
Reprogramming Approaches to Cardiac Disease


Thursday, February 24 | 8:00AM - 11:00AM
Directed Differentiation of Cardiac Progenitors
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 3 of 6
Michael D. Schneider, Imperial College London, UK
Cardiopoiesis: Genetic Circuits for Cardiac Myocyte Creation by Stem Cells


Thursday, February 24 | 8:00AM - 11:00AM
Directed Differentiation of Cardiac Progenitors
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 4 of 6
Christine L. Mummery, Leiden University Medical Center, Netherlands
Cardiomyocytes from Pleuripotent Stem Cells in Drug Discovery and Disease


Thursday, February 24 | 8:00AM - 11:00AM
Directed Differentiation of Cardiac Progenitors
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 5 of 6
Benoit G. Bruneau, Gladstone Institutes, USA
Epigenetic Regulation of Heart Development


Thursday, February 24 | 8:00AM - 11:00AM
Directed Differentiation of Cardiac Progenitors
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 6 of 6
Robert J. Schwartz, Texas A&M University, USA
Short Talk: Trans-differentiation of Noncardiogenic Fibroblast into Cardiac Progenitors


Thursday, February 24 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, February 24 | 11:00AM - 1:00PM
Poster Setup
Room: Quandary Peak


Thursday, February 24 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Thursday, February 24 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary Peak


Thursday, February 24 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, February 24 | 5:00PM - 7:00PM
Ca++ Dynamics and Heart Failure
Room: Longs Peak

Speaker 1 of 4
* Roger J. Hajjar, Mount Sinai School of Medicine, USA

Thursday, February 24 | 5:00PM - 7:00PM
Ca++ Dynamics and Heart Failure
Room: Longs Peak

Speaker 2 of 4
W. Jonathan Lederer, University of Maryland Baltimore, USA
Stretch-dependent Ca2+ signaling in rat and mouse cardiac ventricular myocytes

Thursday, February 24 | 5:00PM - 7:00PM
Ca++ Dynamics and Heart Failure
Room: Longs Peak

Speaker 3 of 4
Joseph M. Metzger, University of Minnesota Medical School, USA
New Delayed Ca2+ Buffer for the Failing Heart

Thursday, February 24 | 5:00PM - 7:00PM
Ca++ Dynamics and Heart Failure
Room: Longs Peak

Speaker 4 of 4
Evangelia G. Kranias, University of Cincinnati College of Medicine, USA
Ca-Cycling Circuits in Heart Failure

Thursday, February 24 | 5:00PM - 7:00PM
Cardiac Death Programs
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 1 of 4
* Richard N. Kitsis, Albert Einstein College of Medicine, USA


Thursday, February 24 | 5:00PM - 7:00PM
Cardiac Death Programs
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 2 of 4
Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
Thrombosponin-4 as a Platform for the Adaptive ER Stress Response


Thursday, February 24 | 5:00PM - 7:00PM
Cardiac Death Programs
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 3 of 4
Lorrie A. Kirshenbaum, University of Manitoba, Canada
Novel Alternative Splicing of Death Gene Bnip3 Promotes Cell Survival of Post-Natal Ventricular Myocytes


Thursday, February 24 | 5:00PM - 7:00PM
Cardiac Death Programs
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 4 of 4
Junichi Sadoshima, Rutgers New Jersey Medical School, USA
Signaling Mechanism of Autophagy in the Heart


Thursday, February 24 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Thursday, February 24 | 7:30PM - 10:00PM
Poster Session 2
Room: Quandary Peak


Friday, February 25 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Friday, February 25 | 8:00AM - 11:00AM
'Wntch' Signaling in Cardiogenesis and Repair (Joint)
Room: Longs/Grays Peak

Speaker 1 of 5
* Charles E. Murry, University of Washington, USA

Friday, February 25 | 8:00AM - 11:00AM
'Wntch' Signaling in Cardiogenesis and Repair (Joint)
Room: Longs/Grays Peak

Speaker 2 of 5
Gordon M. Keller, University Health Network, MaRS Centre, Canada
Induction and Specification of Cardiac Mesoderm from Human Pluripotent Stem Cells

Friday, February 25 | 8:00AM - 11:00AM
'Wntch' Signaling in Cardiogenesis and Repair (Joint)
Room: Longs/Grays Peak

Speaker 3 of 5
Jonathan A. Epstein, University of Pennsylvania, USA
Notch…and other Stories

Friday, February 25 | 8:00AM - 11:00AM
'Wntch' Signaling in Cardiogenesis and Repair (Joint)
Room: Longs/Grays Peak

Speaker 4 of 5
Kenneth R. Chien, Karolinska Institutet, Sweden
Engineering Ventriculogenesis: Epigenetic and Modified RNA Pathway and Technology

Friday, February 25 | 8:00AM - 11:00AM
'Wntch' Signaling in Cardiogenesis and Repair (Joint)
Room: Longs/Grays Peak

Speaker 5 of 5
Edward E. Morrisey, University of Pennsylvania, USA
Wnt Signaling, Cardiac Development and iPSCs

Friday, February 25 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Friday, February 25 | 11:00AM - 1:00PM
Poster Setup
Room: Quandary Peak


Friday, February 25 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Friday, February 25 | 1:00PM - 10:00PM
Poster Viewing
Room: Quandary Peak


Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 1 of 8
* Ivor J. Benjamin, University of Utah, USA

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 2 of 8
* Richard N. Kitsis, Albert Einstein College of Medicine, USA

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 3 of 8
* Leslie A. Leinwand, University of Colorado Boulder, USA

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 4 of 8
* Charles E. Murry, University of Washington, USA

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 5 of 8
Pontus Boström, Dana Farber Cancer Institute, Harvard Medical School, USA
C/EBPbeta Controls Exercise-Induced Cardiac Growth and Protects Against Pathological Cardiac Remodeling

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 6 of 8
Oscar Abilez, Stanford University, USA
In Vitro and In Silico Optogenetic Control of Differentiated Human Pluripotent Stem Cell-Derived Cardiomyocytes

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 7 of 8
Stacey L. Rentschler, Washington University School of Medicine, USA
Notch Signaling Regulates Murine Atrioventricular Conduction and Formation of Accessory Pathways

Friday, February 25 | 3:30PM - 4:30PM
Workshop 2: Graduate Student and Postdoc Research Competitio
n (Joint)
Room: Longs/Grays Peak
The postdoc/graduate student competition is open to all postdocs/graduate students. There will be no reference to age. Abstracts submitted to this competition will be rated by the organizers. The top submissions will be selected for oral presentation in these sessions in addition to poster sessions.
Speaker 8 of 8
Jennifer M. Davis, Cincinnati Children's Hospital Medical Center, USA
TRPC6 Promotes the Fibroblast to Myofibroblast Transition in Cardiac Fibroblasts

Friday, February 25 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Friday, February 25 | 5:00PM - 7:00PM
Nutrition, Energetics, and Signaling
Room: Longs Peak

Speaker 1 of 5
* Evangelia G. Kranias, University of Cincinnati College of Medicine, USA

Friday, February 25 | 5:00PM - 7:00PM
Nutrition, Energetics, and Signaling
Room: Longs Peak

Speaker 2 of 5
Leslie A. Leinwand, University of Colorado Boulder, USA
Gender, Diet, and Cardiac Function

Friday, February 25 | 5:00PM - 7:00PM
Nutrition, Energetics, and Signaling
Room: Longs Peak

Speaker 3 of 5
David D. Thomas, University of Minnesota Medical School, USA
Biophysical Assault on Heart Failure

Friday, February 25 | 5:00PM - 7:00PM
Nutrition, Energetics, and Signaling
Room: Longs Peak

Speaker 4 of 5
Daniel P. Kelly, University of Pennsylvania, USA
Transcriptional Regulation of Cardiac Energetics

Friday, February 25 | 5:00PM - 7:00PM
Nutrition, Energetics, and Signaling
Room: Longs Peak

Speaker 5 of 5
DeWayne Townsend, University of Minnesota Medical School, USA
Short Talk: Loss of Dystrobrevin Markedly Weakens the Interaction between Dystrophin and beta-Dystroglycan, but Cardiac Function is Maintained

Friday, February 25 | 5:00PM - 7:00PM
Translating the (Pluri)Potential into Therapy
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 1 of 5
* Doris A. Taylor, Texas Heart Institute, USA


Friday, February 25 | 5:00PM - 7:00PM
Translating the (Pluri)Potential into Therapy
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 2 of 5
Bernd K. Fleischmann, Bonn University, Germany
The Physiological Basis for Cardiac Repair by Stem Cells


Friday, February 25 | 5:00PM - 7:00PM
Translating the (Pluri)Potential into Therapy
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 3 of 5
Gordana V. Vunjak-Novakovic, Columbia University, USA
Tissue Engineered Cardiac patch


Friday, February 25 | 5:00PM - 7:00PM
Translating the (Pluri)Potential into Therapy
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 4 of 5
Joseph Gold, Beckman Research Institute, City of Hope, USA
Development Human Embryonic Stem Cell-Derived Therapies for the Treatment of Human Disease: Applications in Spinal Cord Injury and Heart Failure


Friday, February 25 | 5:00PM - 7:00PM
Translating the (Pluri)Potential into Therapy
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 5 of 5
Joseph A. Hill, University of Texas Southwestern Medical Center, USA
Short Talk: Mending the Broken Heart: Better Living Through Chemistry


Friday, February 25 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Friday, February 25 | 7:30PM - 10:00PM
Poster Session 3
Room: Quandary Peak


Saturday, February 26 | 7:00AM - 8:00AM
Breakfast
Room: Quandary Peak


Saturday, February 26 | 8:00AM - 11:00AM
Intercellular and Intracellular Communication
Room: Longs Peak

Speaker 1 of 6
* Joseph M. Metzger, University of Minnesota Medical School, USA

Saturday, February 26 | 8:00AM - 11:00AM
Intercellular and Intracellular Communication
Room: Longs Peak

Speaker 2 of 6
Kenneth Walsh, University of Virginia School of Medicine, USA
Signaling between Cardiac Myocytes and Endothelial Cells

Saturday, February 26 | 8:00AM - 11:00AM
Intercellular and Intracellular Communication
Room: Longs Peak

Speaker 3 of 6
Richard T. Lee, Harvard University, USA
Paracrine Signaling Between Fibroblasts and Myocytes

Saturday, February 26 | 8:00AM - 11:00AM
Intercellular and Intracellular Communication
Room: Longs Peak

Speaker 4 of 6
Gerald W. Dorn, II, Washington University School of Medicine, USA
Cross-Talk between ER and Mitochondria

Saturday, February 26 | 8:00AM - 11:00AM
Intercellular and Intracellular Communication
Room: Longs Peak

Speaker 5 of 6
Yibin Wang, University of California, Los Angeles, David Geffen School of Medicine, USA
A Mitochondrial Protein Phosphatase in Cardiac Regulation

Saturday, February 26 | 8:00AM - 11:00AM
Intercellular and Intracellular Communication
Room: Longs Peak

Speaker 6 of 6
Daniela C. Tirziu, Yale University School of Medicine, USA
Short Talk: Role of Nitric Oxide-G Protein Axis in Endothelium to Cardiomyocyte Crosstalk

Saturday, February 26 | 8:00AM - 11:00AM
Identification and Manipulation of Progenitor Cells
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 1 of 6
* Benoit G. Bruneau, Gladstone Institutes, USA


Saturday, February 26 | 8:00AM - 11:00AM
Identification and Manipulation of Progenitor Cells
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 2 of 6
Charles E. Murry, University of Washington, USA
Human Cardiogenesis: Lessons on Growing Cardiomyocytes and Myocardium from Pluripotent Cells


Saturday, February 26 | 8:00AM - 11:00AM
Identification and Manipulation of Progenitor Cells
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 3 of 6
Daniel J. Garry, University of Minnesota, USA
Nkx2-5 Transcriptional Networks and Cardiogenesis


Saturday, February 26 | 8:00AM - 11:00AM
Identification and Manipulation of Progenitor Cells
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 4 of 6
Bernhard Kühn, Children's Hospital of Pittsburgh, USA
Inducing Myocardial Regeneration to Hreat Heart Disease


Saturday, February 26 | 8:00AM - 11:00AM
Identification and Manipulation of Progenitor Cells
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 5 of 6
William T. Pu, Children's Hospital, Harvard Medical School, USA
More than a Cover: Epicardial Function in Heart Development and Disease


Saturday, February 26 | 8:00AM - 11:00AM
Identification and Manipulation of Progenitor Cells
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 6 of 6
Paul H. Goldspink, Medical College of Wisconsin, USA
Short Talk: The E-Domain of MGF Preserves Cardiac Function and Mobilizes Cardiac Progenitor Cell Populations following Myocardial Infarction


Saturday, February 26 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Saturday, February 26 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Saturday, February 26 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Saturday, February 26 | 5:00PM - 7:00PM
Bench to Bedside: Experimental Therapeutics
Room: Longs Peak

Speaker 1 of 5
* Anthony Rosenzweig, Massachusetts General Hospital, USA

Saturday, February 26 | 5:00PM - 7:00PM
Bench to Bedside: Experimental Therapeutics
Room: Longs Peak

Speaker 2 of 5
Eva van Rooij, Hubrecht Institute, Netherlands
Oligo-Based Modulation of miRNAs to Control Cardiovascular Disease

Saturday, February 26 | 5:00PM - 7:00PM
Bench to Bedside: Experimental Therapeutics
Room: Longs Peak

Speaker 3 of 5
Roger J. Hajjar, Mount Sinai School of Medicine, USA
Manipulating SERCA2a in Heart Failure: Basic Mechanisms to Clinical Applications

Saturday, February 26 | 5:00PM - 7:00PM
Bench to Bedside: Experimental Therapeutics
Room: Longs Peak

Speaker 4 of 5
Bruce E. Markham, Phrixus Pharmaceuticals, USA
Membrane Repair, Triblock Co-Polymers and Heart Failure

Saturday, February 26 | 5:00PM - 7:00PM
Bench to Bedside: Experimental Therapeutics
Room: Longs Peak

Speaker 5 of 5
Yang Xiang, University of California, Davis, USA
Short Talk: Spatiotemporal Regulation of beta Adrenergic Receptor Signaling in Cardiac Myocytes

Saturday, February 26 | 5:00PM - 7:00PM
Cardiac Rebirth and Renewal
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 1 of 5
* Jonathan A. Epstein, University of Pennsylvania, USA


Saturday, February 26 | 5:00PM - 7:00PM
Cardiac Rebirth and Renewal
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 2 of 5
Loren J. Field, Indiana University, School of Medicine, USA
Cell Cycle Induction and Stem Cell Mobilization for Cardiomyocyte Repopulation


Saturday, February 26 | 5:00PM - 7:00PM
Cardiac Rebirth and Renewal
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 3 of 5
Michael A. Laflamme, University Health Network, Canada
Human Embryonic Stem Cell-Derived Cardiomyocytes and the Risk of Graft-Related Arrhythmias


Saturday, February 26 | 5:00PM - 7:00PM
Cardiac Rebirth and Renewal
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 4 of 5
Doris A. Taylor, Texas Heart Institute, USA
Cells, Molecules and Matrix: New Tools for Regeneration


Saturday, February 26 | 5:00PM - 7:00PM
Cardiac Rebirth and Renewal
This session is from Cardiac Growth / Regeneration
Room: Grays Peak

Speaker 5 of 5
Hesham A. Sadek, University of Texas Southwestern Medical Center, USA
Short Talk: Heart Regeneration in Neonatal Mice


Saturday, February 26 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Quandary Peak


Saturday, February 26 | 8:00PM - 11:00PM
Entertainment
Room: Quandary Peak


Saturday, February 26 | 8:00PM - 11:00PM
Cash Bar
Room: Quandary Peak


Sunday, February 27 | 10:25AM - 10:25AM
Departure


*Session Chair.