Web Desc
Mucosal Biology: A Fine Balance between Tolerance and Immunity
joint with Immunity in the Respiratory Tract: Challenges of the Lung Environment
Organizer(s): Joanne L. Viney, Paul Garside and Bana Jabri
Date: February 26 - March 03, 2011
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada
Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation
Summary of Meeting:
Experts from the basic science and clinical fields of mucosal biology will be brought together with leaders from other scientific disciplines for a stimulating discussion on the mechanisms regulating the maturation, development and maintenance of mucosal responses in health and disease. Attention will be given to gut, lung, skin, eye and genitourinary tract tissues. The latest information on novel cell types and receptors important for regulating immunity and enhancing mucosal protection will be presented. The influence of infection on driving altered host immunity will be interrogated. Modern approaches to vaccine development and imaging technology will be highlighted. And, the most up to date advances from the physical sciences and engineering will be discussed as we look to the medical needs and developments of the future.
Global Health Travel Award Deadline: September 21 2010
Scholarship Deadline: October 26 2010
Discounted Abstract Deadline: October 26 2010
Abstract Deadline: November 29 2010
Discounted Registration Deadline: December 27 2010
We gratefully acknowledge additional support for this conference from:
Bill & Melinda Gates FoundationCrohn
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Educational donation provided by Amgen
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI092847-01

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-02
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Saturday, February 26 | 3:00PM - 7:30PM
Registration
Room: BC Foyer


Saturday, February 26 | 6:15PM - 7:15PM
Refreshments
Room: BC Foyer


Saturday, February 26 | 7:15PM - 8:30PM
Welcome and Keynote Address (Joint)
Room: British Columbia Ballroom

Speaker 1 of 2
* Joanne L. Viney, Pandion Therapeutics, USA

Saturday, February 26 | 7:15PM - 8:30PM
Welcome and Keynote Address (Joint)
Room: British Columbia Ballroom

Speaker 2 of 2
Patrick G. Holt, University of Western Australia, Australia
Immunity and Inflammation in the Lung – Bridging Innate and Adaptive Immunity

Sunday, February 27 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Sunday, February 27 | 8:00AM - 11:15AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 1 of 6
Alice Prince, Columbia University, USA
Participation of Airway Epithelial Signalling in the Response to Bacterial Infection

Sunday, February 27 | 8:00AM - 11:15AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 2 of 6
Cedar J. Fowler, National Institutes of Infectious Diseases, USA
Short Talk: Exploring Pattern-Recognition Receptors and Ciliary Function Utilizing Primary Respiratory Epithelial Cell Cultures

Sunday, February 27 | 8:00AM - 11:15AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 3 of 6
* Marco Colonna, Washington University School of Medicine, USA
Functional Plasticity of Human NK-22 Cells

Sunday, February 27 | 8:00AM - 11:15AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 4 of 6
* Bana Jabri, University of Chicago, USA
IL-15, a Checkpoint in Tissue Immunity

Sunday, February 27 | 8:00AM - 11:15AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 5 of 6
Shipra Vaishnava, University of Texas Southwestern Medical Center, USA
Short Talk: The Antibacterial C-Type Lectin RegIIIgamma Maintains Spatial Segregation between Microbiota and Host in the Intestine

Sunday, February 27 | 8:00AM - 11:15AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 6 of 6
Dana Philpott, University of Toronto, Canada
Nod1 and Nod2 in Mucosal Defence

Sunday, February 27 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Sunday, February 27 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Sunday, February 27 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Sunday, February 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 1 of 10
* Maria T. Abreu, University of Miami, Miller School of Medicine, USA

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 2 of 10
* Paul Garside, University of Glasgow, UK

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 3 of 10
Thomas A. Wynn, Pfizer, USA
The IL-13 Decoy Receptor Tightly Controls Pathogenic Th17 and Th2 Responses in the Mucosa

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 4 of 10
Tomohiro Yoshimoto, Hyogo College of Medicine, Japan
Role of IL-33 in Experimental Allergic Conjunctivitis

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 5 of 10
Donald N. Cook, NIEHS, National Institutes of Health, USA
LPS Promotes IL-35-Dependent Suppression of Allergen-Induced Airway Disease

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 6 of 10
Anthony Cao, University of Texas Medical Branch, USA
Th17 Cells Contribute to Intestinal Homeostasis by Inducing Intestinal IgA and pIgR Expression

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 7 of 10
Alexander F. Heiseke, Technical University Munich, Germany
CCL17 Drives Intestinal Inflammation and Counteracts Foxp3-Mediated Protection from Colitis

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 8 of 10
Pim J. Koelink, Utrecht University, Netherlands
Proline-Glycine-Proline, a Chemotactic Collagen Breakdown Product, is Involved in Inflammatory Bowel Diseases: Future Target?

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 9 of 10
Rose L. Szabady, Vedanta Biosciences, USA
A Novel Pathogenic Role for IL-22 in Chronic Intestinal Inflammation

Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
Room: British Ballroom

Speaker 10 of 10
Jennifer H. Cox, Chinook Therapeutics Inc, Canada
Dichotomous Consequences of IL-23 Signaling in Chemically Induced Colitis in Mice

Sunday, February 27 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
Room: British Ballroom

Speaker 1 of 4
* Hilde Cheroutre, La Jolla Institute for Allergy and Immunology, USA
Protecting the Border with a Fake ID: CD4 T Cells Stretch Beyond Plasticity

Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
Room: British Ballroom

Speaker 2 of 4
* Joanne L. Viney, Pandion Therapeutics, USA
Butyrophilins: Complexity in Costimulation at the Mucosal Surface

Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
Room: British Ballroom

Speaker 3 of 4
Vanessa Beatriz Freitas Alves, Federal University of Triângulo Mineiro, Brazil
Short Talk: Human Mesenchymal Stromal Cells (Msc) Modulate Gut Inflammation and Th17 Responses In Experimental Inflammatory Bowel Disease

Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
Room: British Ballroom

Speaker 4 of 4
Maria T. Abreu, University of Miami, Miller School of Medicine, USA
Recent Advances in IBD Therapy

Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 1 of 4
Adolfo García-Sastre, Mount Sinai School of Medicine, USA
Innate Immune Responses to Influenza Viruses


Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 2 of 4
* Shawn J. Skerrett, University of Washington, USA
Innate Immunity to Bacterial Pneumonia


Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 3 of 4
Uwe Koppe, Charité University Medicine Berlin, Germany
Short Talk: Streptococcus pneumoniae Activates a Type I Interferon Response Depending on Pneumolysin as Well as the Host Cell Molecules STING and IRF3


Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 4 of 4
* Patricia W. Finn, University of Illinois, USA
Innate Immune Responses in Asthma


Sunday, February 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Sunday, February 27 | 7:30PM - 10:00PM
Poster Session 1
Room: Pacific Ballroom


Monday, February 28 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
Room: British Ballroom

Speaker 1 of 6
* Thaddeus S. Stappenbeck, Cleveland Clinic, USA
Chronic Viral Infection, Autophagy and IBD

Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
Room: British Ballroom

Speaker 2 of 6
* Genoveffa Franchini, NCI, National Institutes of Health, USA
Is the Direct Targeting of the Mucosa Necessary for an HIV Vaccine?

Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
Room: British Ballroom

Speaker 3 of 6
Yongjun Sui, National Institutes of Health, USA
Short Talk: TLR Agonists and/or IL-15 Adjuvanted Mucosal SIV-Vaccine Prevented Gut CD4+ Memory T Cell Loss After SIVmac251-Challenge in Macaques

Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
Room: British Ballroom

Speaker 4 of 6
Jo-Ann S. Passmore, University of Cape Town, South Africa
An African Perspective on Inflammation and Activation in the Female Genital Tract during HIV Infection

Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
Room: British Ballroom

Speaker 5 of 6
Elisabeth Menu, Institut Pasteur, France
Short Talk: Mucosal Innate Immunity and Natural Control of HIV-1 Transmission during Human Pregnancy

Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
Room: British Ballroom

Speaker 6 of 6
Haina Shin, Washington University, USA
Prime and Pull: Protection against Genital HSV Infection

Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 1 of 5
Thomas J. Braciale, University of Virginia, USA
Regulating Inflammation during the Host Response to Respiratory Virus Infection: It's about Self Control


Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 2 of 5
* Andrew D. Luster, Massachusetts General Hospital, USA
Chemokine Control of Effector and Regulatory T Cell Trafficking into the Lung


Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 3 of 5
David L. Woodland, Keystone Symposia on Molecular and Cellular Biology, USA
Regulation of T Cell Immunity to Respiratory Virus Infections


Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 4 of 5
Emily E. Thornton, University of Oxford, UK
Short Talk: Lung Surveillance Revealed by Two-Photon Live Imaging


Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses
This session is from Immunity in Respir Tract

Room: Columbia Ballroom

Speaker 5 of 5
Berber Piet, Academic Medical Center, Netherlands
Short Talk: Lymphocytes in the Frontline; Human Lung CD8+ T Cells Recognizing Influenza Virus Reside in Airway Epithelium


Monday, February 28 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Monday, February 28 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Monday, February 28 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Monday, February 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 1 of 9
* Joanne L. Viney, Pandion Therapeutics, USA

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 2 of 9
* Cherié L. Butts, Biogen Inc, USA

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 3 of 9
Katherine Arias, McMaster University, Canada
Evolution of Immune-Suppressive and Immune-Responsive Capacities in the Lung during Development in Mice

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 4 of 9
Pejman Soroosh, Janssen R&D, USA
Essential Role of Lung Resident Macrophages in Regulating Airway Tolerance in Response to Innocuous Inhaled Antigen

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 5 of 9
Dorothée Duluc, Baylor Institute for Immunology Research, USA
Characterization of Dendritic Cell Subsets in Human Vaginal Mucosa

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 6 of 9
Barbara Cassani, Massachusetts General Hospital, USA
Gut-Specific Lymphocyte Homing as a Key Player in Oral Immunological Tolerance

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 7 of 9
Usriansyah Hadis, Hannover Medical School, Germany
Cooperation of Lymph Nodes and Intestinal Lamina Propria
in Foxp3+ Regulatory T Cell Mediated Intestinal Tolerance


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 8 of 9
Oscar Medina-Contreras, Georgia State University, USA
CX3CR1 Regulates Intestinal Macrophage Homeostasis, Bacterial Translocation and Colitis

Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
Room: British Ballroom

Speaker 9 of 9
Rajesh (Nair) Ravindran, Emory University, USA
Oral Delivery of TLR Ligands Programs Splenic Dendritic Cells to Induce T Regulatory Responses

Monday, February 28 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct

Room: British Ballroom

Speaker 1 of 4
* Shannon J. Turley, Genentech, Inc., USA
Regulation of Dendritic Cell and T Cell Function by Lymphoid Stroma

Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct

Room: British Ballroom

Speaker 2 of 4
* Rachel R. Caspi, NEI, National Institutes of Health, USA
Ocular Immune Privilege, T Regulatory Cells and Autoimmunity

Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct

Room: British Ballroom

Speaker 3 of 4
Thomas J. Hannan, Fimbrion Therapeutics, Inc., USA
Short Talk: Innate and Adaptive Mucosal Immune Checkpoints in Chronic and Recurrent Bacterial Cystitis

Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct

Room: British Ballroom

Speaker 4 of 4
Sarah Howie, University of Edinburgh, UK
Immunoregulation in the Female Reproductive Tract

Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 1 of 4
* Graham S. Le Gros, Malaghan Institute of Medical Research, New Zealand
Anti-Helminth Immunity in the Airways


Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 2 of 4
Yui-Hsi Wang, Cincinnati Childrens' Hospital, USA
Short Talk: A Novel Subset of TH2 Memory/Effector Cells that Produce Inflammatory IL-17 Cytokine and Promote the Exacerbation of Allergic Asthma


Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 3 of 4
Nicholas W. Lukacs, University of Michigan, USA
Chemokines and Respiratory Immune Responses


Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 4 of 4
Clifford V. Harding, Case Western Reserve University, USA
Toll-Like Receptor Regulation of Antigen-Presenting Cells and Responses to Mycobacterium tuberculosis


Monday, February 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Monday, February 28 | 7:30PM - 10:00PM
Poster Session 2
Room: Pacific Ballroom


Tuesday, March 01 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 1 of 7
* Dominique Kaiserlian, INSERM U851, France
Oral tolerance: Respective Roles of Liver, MLN and the Gut Flora

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 2 of 7
Eduardo J. Villablanca, Karolinska Institute, Sweden
Short Talk: MyD88-Dependent Signals Synergize with Retinoic Acid to Educate Gut-Associated Dendritic Cells

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 3 of 7
Kayla A. Weiss, University of Iowa, USA
Short Talk: Multiple CD4+ T Cell Subsets Produce Immunomodulatory IL-10 during Acute Respiratory Syncytial Virus Infection

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 4 of 7
* Yasmine Belkaid, NIAID, National Institutes of Health, USA
Roles of Retinoic Acid in Immunity

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 5 of 7
Cherié L. Butts, Biogen Inc, USA
Short Talk: Immunomodulatory Role of Progesterone on Immune Cell Function in Uterine and Other Tissues

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 6 of 7
De' Broski R. Herbert, University of Pennsylvania, USA
Short Talk: Epithelial Cells Promote Th2 Immunity Against Parasitic Helminths

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 7 of 7
Wenjun Ouyang, Amgen, Inc., USA
The Functions of IL-22 in Mucosal Immunity

Tuesday, March 01 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Tuesday, March 01 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Tuesday, March 01 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Tuesday, March 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 1 of 10
* Dana Philpott, University of Toronto, Canada

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 2 of 10
* Gérard Eberl, Institut Pasteur, France

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 3 of 10
Soumita Das, University of California, San Diego, USA
Recognition of Enteric Bacteria by a New Pattern Recognition Receptor BAI1 (Brain Angiogenesis Inhibitor 1)

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 4 of 10
R. William DePaolo, University of Washington, USA
Regulation of Anti-Microbial Peptides and IL-17 by TLR1 during Oral Yersinia Enterocolitica Infection

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 5 of 10
Akhilesh Singh, Seattle Children's Research Institute, USA
TLR5 Ligand Stimulates Colonic IL-22 Production by LTi-like Cells in an IL-23R Independent Fashion

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 6 of 10
Melissa A. Kinnebrew, Memorial Sloan-Kettering Cancer Center, USA
Mediators of Flagellin Induced IL-22 Expression at the Intestinal Mucosa

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 7 of 10
Irene Jarchum, Nature, USA
Toll-Like Receptor 5 Stimulation Protects Mice from Clostridium Difficile Colitis

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 8 of 10
Naohiro Inohara, University of Michigan Medical School, USA
Nod1 Prevents Systemic Inflammation by Recruiting Neutrophils to Clear Translocated Commensals after Clostridium Difficile Infection

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 9 of 10
Kaoru Geddes, University of Toronto, Canada
Nod Proteins Regulate Intestinal Inflammation

Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
Room: British Ballroom

Speaker 10 of 10
Jooeun Lee, University of Toronto, Canada
The Interplay between Nod1 and PGLYRP2 in Mucosal Immunity

Tuesday, March 01 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
Room: British Ballroom

Speaker 1 of 4
* Jo Spencer, King's College London, UK
Generation and Diversification of Human IgA Responses in Gut-Associated Lymphoid Tissue

Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
Room: British Ballroom

Speaker 2 of 4
Duane R. Wesemann, Harvard Medical School, USA
Short Talk: Extramedullary V(D)J Recombination in Gut Lamina Propria B Lineage Cells

Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
Room: British Ballroom

Speaker 3 of 4
* Andrea Cerutti, Mount Sinai School of Medicine, USA
Regulation of Splenic Marginal Zone B Cell Responses by Mucosal Signals

Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
Room: British Ballroom

Speaker 4 of 4
Gérard Eberl, Institut Pasteur, France
Symbiotic Bacteria and Proinflammatory Immunity

Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 1 of 5
* Liise-anne Pirofski, Albert Einstein College of Medicine and Montefiore Medical Center, USA
Antibody-Mediated Damage Control


Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 2 of 5
Marianne L. Boes, University Medical Centre, Netherlands
Short Talk: Defective BCR Internalization and Calcium Mobilization in Common Variable Immunodeficiency (CVID)


Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 3 of 5
* Joseph P. Mizgerd, Boston University School of Medicine, USA
Signaling Hubs Balancing Host Defense and Lung Injury during Pneumonia


Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 4 of 5
Cheri Sirois, Cell Press, USA
Short Talk: RAGE Promotes Inflammatory Responses to DNA in the Lung


Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 5 of 5
Catherine J. Sanders, St. Jude Children's Research Hospital, USA
Short Talk: IL-1 Signaling in Lung Recovery from Influenza-Induced Damage


Tuesday, March 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Tuesday, March 01 | 7:30PM - 10:00PM
Poster Session 3
Room: Pacific Ballroom


Wednesday, March 02 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment

Room: British Ballroom

Speaker 1 of 5
* Paul Garside, University of Glasgow, UK
Visualizing Tolerance vs. Priming in vivo Using Novel Imaging, Labeling and Tracking Technologies

Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment

Room: British Ballroom

Speaker 2 of 5
* Ramnik Xavier, Massachusetts General Hospital, USA
Protein Domains, Signaling Networks, and Immunity

Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment

Room: British Ballroom

Speaker 3 of 5
Xiaoxiao Li, University of California, Los Angeles, USA
Short Talk: Detecting Disease-Related Biologic Neighborhoods by Metaproteomic Analysis at Mucosal-Luminal Interface

Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment

Room: British Ballroom

Speaker 4 of 5
Andrew J. Yates, Columbia University, USA
Cytotoxic T Lymphocytes, Virus Strategies and Sterilizing Immunity

Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment

Room: British Ballroom

Speaker 5 of 5
Robert M. Hershberg, VentiRx Pharmaceuticals, USA
Novel TLR Therapies for Treating Allergic Rhinitis and Asthma

Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 1 of 6
* Allen G. Harmsen, Montana State University, USA
Nonspecific Enhancement of Resistance to Lung Viruses by Nanoparticle-Induction of BALT


Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 2 of 6
Troy D. Randall, University of Alabama at Birmingham, USA
Lung Lymphoid Tissue and Regulation of Local Immune Responses


Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 3 of 6
* Arturo Casadevall, Albert Einstein College of Medicine, USA
Antibody-Based Therapies: Promise and Complexity


Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 4 of 6
Scott E. Evans, University of Texas MD Anderson Cancer Center, USA
Short Talk: Epithelial Resistance to Pneumonia Induced by TLR Synergy


Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 5 of 6
Jory R. Baldridge, GlaxoSmithKline, USA
TLR4 Agonists Facilitate “Rapid Acting Vaccine” Against the Respiratory Tract Pathogen, Influenza A


Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 6 of 6
François Coulombe, Laval University, Canada
Short Talk: Muramyl Dipeptide Induces NOD2-Dependent Modulation of Protective Host Response Against Influenza Virus


Wednesday, March 02 | 9:00AM - 9:20AM
Coffee Break
Room: BC Foyer


Wednesday, March 02 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Wednesday, March 02 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Wednesday, March 02 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 1 of 9
* Bana Jabri, University of Chicago, USA

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 2 of 9
* De' Broski R. Herbert, University of Pennsylvania, USA

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 3 of 9
Paria Mirmonsef, Rush University Medical Center, USA
Activation of Mucosal Innate Immune Responses by Short Chain Fatty Acids and Toll-Like Receptor Ligands

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 4 of 9
Yuko Akiyama, University of Tokyo, Japan
Dual Role of Epithelial Fucosylation in the Small Intestine: Co-Habitation and Defense Niches for Commensal and Pathogenic Bacteria

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 5 of 9
Sin-Hyeog Im, POSTECH, South Korea
IRT5 Probiotics as an Immune Modulator for Diverse Immune Disorders

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 6 of 9
Gwo-Tzer Ho, University of Edinburgh, UK
Epithelial Multidrug Resistance-1 (MDR1) Gene Modulates Specific NF-kappaB-Response to Bacterial Flagellin and Promotes a Pro-Inflammatory Response in the Intestinal Epithelium

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 7 of 9
Mahima Swamy, London Research Institute, Cancer Research UK, UK
Understanding IEL Epithelium Interactions in the Gut

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 8 of 9
Lionel Le Bourhis, Institut Curie, France
Mucosal Associated Invariant T Cells Function in the Intestine

Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
Room: British Ballroom

Speaker 9 of 9
Bjoern Ole Schroeder, Sahlgrenska Academy at University of Gothenburg, Sweden
Reduced to Action: Human beta defensin-1 in the Intestine

Wednesday, March 02 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy

Room: British Ballroom

Speaker 1 of 4
* John D. Rioux, Montreal Heart Institute and Université de Montréal, Canada
What Genetic Studies Are Teaching Us about Mucosal Biology and Intestinal Inflammation

Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy

Room: British Ballroom

Speaker 2 of 4
* Ludvig M. Sollid, University of Oslo, Norway
Autoimmune Dysregulation in Celiac Disease

Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy

Room: British Ballroom

Speaker 3 of 4
Valerie Abadie, University of Chicago, USA
Short Talk: Co-Adjuvant Effects of Retinoic Acid and IL-15
Induce Inflammatory Immunity to Dietary Antigens


Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy

Room: British Ballroom

Speaker 4 of 4
Hugh A. Sampson, Icahn School of Medicine at Mount Sinai, USA
Treating Food Allergy

Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 1 of 4
* Kanta Subbarao, WHO Collaborating Centre for Reference and Research on Influenza, Australia
Local Immunity Induced by Live Attenuated Pandemic Influenza Vaccines


Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 2 of 4
Maytal Bivas-Benita, Beth Israel Deaconess Medical Center/Harvard Medical school, USA
Short Talk: Pulmonary DNA Immunization Generates Antigen-Specific CD8+T Cells in the Lung Airways that Protect Against Respiratory Lethal Viral Challenge


Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 3 of 4
Catharine M. Bosio, NIAID, National Institutes of Health, USA
Requirements for Immunity Against Pneumonic Tularemia


Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
This session is from Immunity in Respir Tract
Room: Columbia Ballroom

Speaker 4 of 4
* Jay K. Kolls, Tulane School of Medicine, USA
Balancing Mucosal Immunity in a Vaccine Context


Wednesday, March 02 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Wednesday, March 02 | 8:00PM - 11:00PM
Entertainment
Room: Pacific Ballroom


Wednesday, March 02 | 8:00PM - 11:00PM
Cash Bar
Room: Pacific Ballroom


Thursday, March 03 | 10:25AM - 10:25AM
Departure


*Session Chair.