Web Desc
Immunity in the Respiratory Tract: Challenges of the Lung Environment
joint with Mucosal Biology: A Fine Balance between Tolerance and Immunity
Organizer(s): David L. Woodland, Liise-anne Pirofski and Allen G. Harmsen
Date: February 26 - March 03, 2011
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada
Sponsored by Hoffmann-La Roche, Inc.
Summary of Meeting:
Recently, there has been an explosion in information about the regulation of inflammation, immunity, and immunopathology in the lung. Despite these advances, we still have only a rudimentary understanding of how these responses relate to the lung environment or how and why they translate into beneficial or detrimental effects, health or disease. The goals of this meeting are to (i) bring together allergists, immunologists, microbiologists and vaccinologists to discuss pulmonary inflammation and immunity in the context of lung biology and (ii) to build on this understanding to develop improved vaccines and therapeutic interventions for inflammatory conditions and infectious diseases that affect the lungs. Expert talks in plenary sessions will present the latest research in the field. Workshops and additional talks will add late-breaking cutting-edge results. The meeting will considerably advance our understanding of respiratory immunity.
Scholarship Deadline: October 26 2010
Discounted Abstract Deadline: October 26 2010
Abstract Deadline: November 29 2010
Discounted Registration Deadline: December 27 2010
We gratefully acknowledge additional support for this conference from:
Burroughs Wellcome FundHoffmann-La Roche, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

GlaxoSmithKline Biologicals
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
S. Karger AG - Respiration
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI092849-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Saturday, February 26 | 3:00PM - 7:30PM
Registration
Room: BC Foyer


Saturday, February 26 | 6:15PM - 7:15PM
Refreshments
Room: BC Foyer


Saturday, February 26 | 7:15PM - 8:30PM
Welcome and Keynote Address (Joint)
Room: British Columbia Ballroom

Speaker 1 of 2
* Joanne L. Viney, Pandion Therapeutics, USA

Saturday, February 26 | 7:15PM - 8:30PM
Welcome and Keynote Address (Joint)
Room: British Columbia Ballroom

Speaker 2 of 2
Patrick G. Holt, University of Western Australia, Australia
Immunity and Inflammation in the Lung – Bridging Innate and Adaptive Immunity

Sunday, February 27 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Sunday, February 27 | 8:00AM - 11:00AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 1 of 6
Alice Prince, Columbia University, USA
Participation of Airway Epithelial Signalling in the Response to Bacterial Infection

Sunday, February 27 | 8:00AM - 11:00AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 2 of 6
Cedar J. Fowler, National Institutes of Infectious Diseases, USA
Short Talk: Exploring Pattern-Recognition Receptors and Ciliary Function Utilizing Primary Respiratory Epithelial Cell Cultures

Sunday, February 27 | 8:00AM - 11:00AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 3 of 6
* Marco Colonna, Washington University School of Medicine, USA
Functional Plasticity of Human NK-22 Cells

Sunday, February 27 | 8:00AM - 11:00AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 4 of 6
* Bana Jabri, University of Chicago, USA
IL-15, a Checkpoint in Tissue Immunity

Sunday, February 27 | 8:00AM - 11:00AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 5 of 6
Shipra Vaishnava, University of Texas Southwestern Medical Center, USA
Short Talk: The Antibacterial C-Type Lectin RegIIIgamma Maintains Spatial Segregation between Microbiota and Host in the Intestine

Sunday, February 27 | 8:00AM - 11:00AM
Innate Immunity at Mucosal Surfaces: The Players (Joint)
Room: British Columbia Ballroom

Speaker 6 of 6
Dana Philpott, University of Toronto, Canada
Nod1 and Nod2 in Mucosal Defence

Sunday, February 27 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Sunday, February 27 | 11:00AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Sunday, February 27 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Sunday, February 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 10
* Maria T. Abreu, University of Miami, Miller School of Medicine, USA


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 10
* Paul Garside, University of Glasgow, UK


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 10
Thomas A. Wynn, Pfizer, USA
The IL-13 Decoy Receptor Tightly Controls Pathogenic Th17 and Th2 Responses in the Mucosa


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 10
Tomohiro Yoshimoto, Hyogo College of Medicine, Japan
Role of IL-33 in Experimental Allergic Conjunctivitis


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 5 of 10
Donald N. Cook, NIEHS, National Institutes of Health, USA
LPS Promotes IL-35-Dependent Suppression of Allergen-Induced Airway Disease


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 6 of 10
Anthony Cao, University of Texas Medical Branch, USA
Th17 Cells Contribute to Intestinal Homeostasis by Inducing Intestinal IgA and pIgR Expression


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 7 of 10
Alexander F. Heiseke, Technical University Munich, Germany
CCL17 Drives Intestinal Inflammation and Counteracts Foxp3-Mediated Protection from Colitis


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 8 of 10
Pim J. Koelink, Utrecht University, Netherlands
Proline-Glycine-Proline, a Chemotactic Collagen Breakdown Product, is Involved in Inflammatory Bowel Diseases: Future Target?


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 9 of 10
Rose L. Szabady, Vedanta Biosciences, USA
A Novel Pathogenic Role for IL-22 in Chronic Intestinal Inflammation


Sunday, February 27 | 2:30PM - 4:30PM
Workshop 1: Cytokines, Chemokines and Mucosal Immunoregulati
on
This session is from Mucosal Biology
Room: British Ballroom

Speaker 10 of 10
Jennifer H. Cox, Chinook Therapeutics Inc, Canada
Dichotomous Consequences of IL-23 Signaling in Chemically Induced Colitis in Mice


Sunday, February 27 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease

Room: Columbia Ballroom

Speaker 1 of 4
Adolfo García-Sastre, Mount Sinai School of Medicine, USA
Innate Immune Responses to Influenza Viruses

Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease

Room: Columbia Ballroom

Speaker 2 of 4
* Shawn J. Skerrett, University of Washington, USA
Innate Immunity to Bacterial Pneumonia

Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease

Room: Columbia Ballroom

Speaker 3 of 4
Uwe Koppe, Charité University Medicine Berlin, Germany
Short Talk: Streptococcus pneumoniae Activates a Type I Interferon Response Depending on Pneumolysin as Well as the Host Cell Molecules STING and IRF3

Sunday, February 27 | 5:00PM - 7:00PM
Lung Innate Immunity and Disease: First Line of Defense to D
isease

Room: Columbia Ballroom

Speaker 4 of 4
* Patricia W. Finn, University of Illinois, USA
Innate Immune Responses in Asthma

Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 4
* Hilde Cheroutre, La Jolla Institute for Allergy and Immunology, USA
Protecting the Border with a Fake ID: CD4 T Cells Stretch Beyond Plasticity


Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 4
* Joanne L. Viney, Pandion Therapeutics, USA
Butyrophilins: Complexity in Costimulation at the Mucosal Surface


Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 4
Vanessa Beatriz Freitas Alves, Federal University of Triângulo Mineiro, Brazil
Short Talk: Human Mesenchymal Stromal Cells (Msc) Modulate Gut Inflammation and Th17 Responses In Experimental Inflammatory Bowel Disease


Sunday, February 27 | 5:00PM - 7:00PM
Mechanisms for Protection from Intestinal Inflammation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 4
Maria T. Abreu, University of Miami, Miller School of Medicine, USA
Recent Advances in IBD Therapy


Sunday, February 27 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Sunday, February 27 | 7:30PM - 10:00PM
Poster Session 1
Room: Pacific Ballroom


Monday, February 28 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses

Room: Columbia Ballroom

Speaker 1 of 5
Thomas J. Braciale, University of Virginia, USA
Regulating Inflammation during the Host Response to Respiratory Virus Infection: It's about Self Control

Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses

Room: Columbia Ballroom

Speaker 2 of 5
* Andrew D. Luster, Massachusetts General Hospital, USA
Chemokine Control of Effector and Regulatory T Cell Trafficking into the Lung

Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses

Room: Columbia Ballroom

Speaker 3 of 5
David L. Woodland, Keystone Symposia on Molecular and Cellular Biology, USA
Regulation of T Cell Immunity to Respiratory Virus Infections

Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses

Room: Columbia Ballroom

Speaker 4 of 5
Emily E. Thornton, University of Oxford, UK
Short Talk: Lung Surveillance Revealed by Two-Photon Live Imaging

Monday, February 28 | 8:00AM - 11:00AM
Navigating the Lung - The Ins and Outs of Adaptive Immune Re
sponses

Room: Columbia Ballroom

Speaker 5 of 5
Berber Piet, Academic Medical Center, Netherlands
Short Talk: Lymphocytes in the Frontline; Human Lung CD8+ T Cells Recognizing Influenza Virus Reside in Airway Epithelium

Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 6
* Thaddeus S. Stappenbeck, Cleveland Clinic, USA
Chronic Viral Infection, Autophagy and IBD


Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 6
* Genoveffa Franchini, NCI, National Institutes of Health, USA
Is the Direct Targeting of the Mucosa Necessary for an HIV Vaccine?


Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 6
Yongjun Sui, National Institutes of Health, USA
Short Talk: TLR Agonists and/or IL-15 Adjuvanted Mucosal SIV-Vaccine Prevented Gut CD4+ Memory T Cell Loss After SIVmac251-Challenge in Macaques


Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 6
Jo-Ann S. Passmore, University of Cape Town, South Africa
An African Perspective on Inflammation and Activation in the Female Genital Tract during HIV Infection


Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
This session is from Mucosal Biology
Room: British Ballroom

Speaker 5 of 6
Elisabeth Menu, Institut Pasteur, France
Short Talk: Mucosal Innate Immunity and Natural Control of HIV-1 Transmission during Human Pregnancy


Monday, February 28 | 8:00AM - 11:15AM
Viruses in Health and Disease
This session is from Mucosal Biology
Room: British Ballroom

Speaker 6 of 6
Haina Shin, Washington University, USA
Prime and Pull: Protection against Genital HSV Infection


Monday, February 28 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Monday, February 28 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Monday, February 28 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Monday, February 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 9
* Joanne L. Viney, Pandion Therapeutics, USA


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 9
* Cherié L. Butts, Biogen Inc, USA


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 9
Katherine Arias, McMaster University, Canada
Evolution of Immune-Suppressive and Immune-Responsive Capacities in the Lung during Development in Mice


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 9
Pejman Soroosh, Janssen R&D, USA
Essential Role of Lung Resident Macrophages in Regulating Airway Tolerance in Response to Innocuous Inhaled Antigen


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 5 of 9
Dorothée Duluc, Baylor Institute for Immunology Research, USA
Characterization of Dendritic Cell Subsets in Human Vaginal Mucosa


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 6 of 9
Barbara Cassani, Massachusetts General Hospital, USA
Gut-Specific Lymphocyte Homing as a Key Player in Oral Immunological Tolerance


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 7 of 9
Usriansyah Hadis, Hannover Medical School, Germany
Cooperation of Lymph Nodes and Intestinal Lamina Propria
in Foxp3+ Regulatory T Cell Mediated Intestinal Tolerance


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 8 of 9
Oscar Medina-Contreras, Georgia State University, USA
CX3CR1 Regulates Intestinal Macrophage Homeostasis, Bacterial Translocation and Colitis


Monday, February 28 | 2:30PM - 4:30PM
Workshop 2: Dendritic Cells, Macrophages and Mucosal Immunor
egulation
This session is from Mucosal Biology
Room: British Ballroom

Speaker 9 of 9
Rajesh (Nair) Ravindran, Emory University, USA
Oral Delivery of TLR Ligands Programs Splenic Dendritic Cells to Induce T Regulatory Responses


Monday, February 28 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
Room: Columbia Ballroom

Speaker 1 of 4
* Graham S. Le Gros, Malaghan Institute of Medical Research, New Zealand
Anti-Helminth Immunity in the Airways

Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
Room: Columbia Ballroom

Speaker 2 of 4
Yui-Hsi Wang, Cincinnati Childrens' Hospital, USA
Short Talk: A Novel Subset of TH2 Memory/Effector Cells that Produce Inflammatory IL-17 Cytokine and Promote the Exacerbation of Allergic Asthma

Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
Room: Columbia Ballroom

Speaker 3 of 4
Nicholas W. Lukacs, University of Michigan, USA
Chemokines and Respiratory Immune Responses

Monday, February 28 | 5:00PM - 7:00PM
Inflammatory Aspects of Adaptive Immunity
Room: Columbia Ballroom

Speaker 4 of 4
Clifford V. Harding, Case Western Reserve University, USA
Toll-Like Receptor Regulation of Antigen-Presenting Cells and Responses to Mycobacterium tuberculosis

Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct
This session is from Mucosal Biology

Room: British Ballroom

Speaker 1 of 4
* Shannon J. Turley, Genentech, Inc., USA
Regulation of Dendritic Cell and T Cell Function by Lymphoid Stroma


Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct
This session is from Mucosal Biology

Room: British Ballroom

Speaker 2 of 4
* Rachel R. Caspi, NEI, National Institutes of Health, USA
Ocular Immune Privilege, T Regulatory Cells and Autoimmunity


Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct
This session is from Mucosal Biology

Room: British Ballroom

Speaker 3 of 4
Thomas J. Hannan, Fimbrion Therapeutics, Inc., USA
Short Talk: Innate and Adaptive Mucosal Immune Checkpoints in Chronic and Recurrent Bacterial Cystitis


Monday, February 28 | 5:00PM - 7:00PM
Control of Immune Responses in the Skin, Eye and Genital Tra
ct
This session is from Mucosal Biology

Room: British Ballroom

Speaker 4 of 4
Sarah Howie, University of Edinburgh, UK
Immunoregulation in the Female Reproductive Tract


Monday, February 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Monday, February 28 | 7:30PM - 10:00PM
Poster Session 2
Room: Pacific Ballroom


Tuesday, March 01 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 1 of 7
* Dominique Kaiserlian, INSERM U851, France
Oral tolerance: Respective Roles of Liver, MLN and the Gut Flora

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 2 of 7
Eduardo J. Villablanca, Karolinska Institute, Sweden
Short Talk: MyD88-Dependent Signals Synergize with Retinoic Acid to Educate Gut-Associated Dendritic Cells

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 3 of 7
Kayla A. Weiss, University of Iowa, USA
Short Talk: Multiple CD4+ T Cell Subsets Produce Immunomodulatory IL-10 during Acute Respiratory Syncytial Virus Infection

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 4 of 7
* Yasmine Belkaid, NIAID, National Institutes of Health, USA
Roles of Retinoic Acid in Immunity

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 5 of 7
Cherié L. Butts, Biogen Inc, USA
Short Talk: Immunomodulatory Role of Progesterone on Immune Cell Function in Uterine and Other Tissues

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 6 of 7
De' Broski R. Herbert, University of Pennsylvania, USA
Short Talk: Epithelial Cells Promote Th2 Immunity Against Parasitic Helminths

Tuesday, March 01 | 8:00AM - 11:15AM
Immunoregulatory Mechanisms (Joint)
Room: British Columbia Ballroom

Speaker 7 of 7
Wenjun Ouyang, Amgen, Inc., USA
The Functions of IL-22 in Mucosal Immunity

Tuesday, March 01 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Tuesday, March 01 | 11:00AM - 11:00AM
On Own for Lunch and Recreation


Tuesday, March 01 | 11:15AM - 1:00PM
Poster Setup
Room: Pacific Ballroom


Tuesday, March 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Pacific Ballroom


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 10
* Dana Philpott, University of Toronto, Canada


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 10
* Gérard Eberl, Institut Pasteur, France


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 10
Soumita Das, University of California, San Diego, USA
Recognition of Enteric Bacteria by a New Pattern Recognition Receptor BAI1 (Brain Angiogenesis Inhibitor 1)


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 10
R. William DePaolo, University of Washington, USA
Regulation of Anti-Microbial Peptides and IL-17 by TLR1 during Oral Yersinia Enterocolitica Infection


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 5 of 10
Akhilesh Singh, Seattle Children's Research Institute, USA
TLR5 Ligand Stimulates Colonic IL-22 Production by LTi-like Cells in an IL-23R Independent Fashion


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 6 of 10
Melissa A. Kinnebrew, Memorial Sloan-Kettering Cancer Center, USA
Mediators of Flagellin Induced IL-22 Expression at the Intestinal Mucosa


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 7 of 10
Irene Jarchum, Nature, USA
Toll-Like Receptor 5 Stimulation Protects Mice from Clostridium Difficile Colitis


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 8 of 10
Naohiro Inohara, University of Michigan Medical School, USA
Nod1 Prevents Systemic Inflammation by Recruiting Neutrophils to Clear Translocated Commensals after Clostridium Difficile Infection


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 9 of 10
Kaoru Geddes, University of Toronto, Canada
Nod Proteins Regulate Intestinal Inflammation


Tuesday, March 01 | 2:30PM - 4:30PM
Workshop 3: NODS/TLRs and Innate Immunity
This session is from Mucosal Biology
Room: British Ballroom

Speaker 10 of 10
Jooeun Lee, University of Toronto, Canada
The Interplay between Nod1 and PGLYRP2 in Mucosal Immunity


Tuesday, March 01 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
Room: Columbia Ballroom

Speaker 1 of 5
* Liise-anne Pirofski, Albert Einstein College of Medicine and Montefiore Medical Center, USA
Antibody-Mediated Damage Control

Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
Room: Columbia Ballroom

Speaker 2 of 5
Marianne L. Boes, University Medical Centre, Netherlands
Short Talk: Defective BCR Internalization and Calcium Mobilization in Common Variable Immunodeficiency (CVID)

Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
Room: Columbia Ballroom

Speaker 3 of 5
* Joseph P. Mizgerd, Boston University School of Medicine, USA
Signaling Hubs Balancing Host Defense and Lung Injury during Pneumonia

Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
Room: Columbia Ballroom

Speaker 4 of 5
Cheri Sirois, Cell Press, USA
Short Talk: RAGE Promotes Inflammatory Responses to DNA in the Lung

Tuesday, March 01 | 5:00PM - 7:00PM
Damage Control
Room: Columbia Ballroom

Speaker 5 of 5
Catherine J. Sanders, St. Jude Children's Research Hospital, USA
Short Talk: IL-1 Signaling in Lung Recovery from Influenza-Induced Damage

Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 4
* Jo Spencer, King's College London, UK
Generation and Diversification of Human IgA Responses in Gut-Associated Lymphoid Tissue


Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 4
Duane R. Wesemann, Harvard Medical School, USA
Short Talk: Extramedullary V(D)J Recombination in Gut Lamina Propria B Lineage Cells


Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 4
* Andrea Cerutti, Mount Sinai School of Medicine, USA
Regulation of Splenic Marginal Zone B Cell Responses by Mucosal Signals


Tuesday, March 01 | 5:00PM - 7:00PM
Mucosal B Cells and Lymphoid Organogenesis
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 4
Gérard Eberl, Institut Pasteur, France
Symbiotic Bacteria and Proinflammatory Immunity


Tuesday, March 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Tuesday, March 01 | 7:30PM - 10:00PM
Poster Session 3
Room: Pacific Ballroom


Wednesday, March 02 | 7:00AM - 8:00AM
Breakfast
Room: Pacific Ballroom


Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
Room: Columbia Ballroom

Speaker 1 of 6
* Allen G. Harmsen, Montana State University, USA
Nonspecific Enhancement of Resistance to Lung Viruses by Nanoparticle-Induction of BALT

Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
Room: Columbia Ballroom

Speaker 2 of 6
Troy D. Randall, University of Alabama at Birmingham, USA
Lung Lymphoid Tissue and Regulation of Local Immune Responses

Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
Room: Columbia Ballroom

Speaker 3 of 6
* Arturo Casadevall, Albert Einstein College of Medicine, USA
Antibody-Based Therapies: Promise and Complexity

Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
Room: Columbia Ballroom

Speaker 4 of 6
Scott E. Evans, University of Texas MD Anderson Cancer Center, USA
Short Talk: Epithelial Resistance to Pneumonia Induced by TLR Synergy

Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
Room: Columbia Ballroom

Speaker 5 of 6
Jory R. Baldridge, GlaxoSmithKline, USA
TLR4 Agonists Facilitate “Rapid Acting Vaccine” Against the Respiratory Tract Pathogen, Influenza A

Wednesday, March 02 | 8:00AM - 11:15AM
Immunotherapy: Helping the Host
Room: Columbia Ballroom

Speaker 6 of 6
François Coulombe, Laval University, Canada
Short Talk: Muramyl Dipeptide Induces NOD2-Dependent Modulation of Protective Host Response Against Influenza Virus

Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment
This session is from Mucosal Biology

Room: British Ballroom

Speaker 1 of 5
* Paul Garside, University of Glasgow, UK
Visualizing Tolerance vs. Priming in vivo Using Novel Imaging, Labeling and Tracking Technologies


Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment
This session is from Mucosal Biology

Room: British Ballroom

Speaker 2 of 5
* Ramnik Xavier, Massachusetts General Hospital, USA
Protein Domains, Signaling Networks, and Immunity


Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment
This session is from Mucosal Biology

Room: British Ballroom

Speaker 3 of 5
Xiaoxiao Li, University of California, Los Angeles, USA
Short Talk: Detecting Disease-Related Biologic Neighborhoods by Metaproteomic Analysis at Mucosal-Luminal Interface


Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment
This session is from Mucosal Biology

Room: British Ballroom

Speaker 4 of 5
Andrew J. Yates, Columbia University, USA
Cytotoxic T Lymphocytes, Virus Strategies and Sterilizing Immunity


Wednesday, March 02 | 8:00AM - 11:15AM
Innovative Approaches in Modern Medicine and Vaccine Develop
ment
This session is from Mucosal Biology

Room: British Ballroom

Speaker 5 of 5
Robert M. Hershberg, VentiRx Pharmaceuticals, USA
Novel TLR Therapies for Treating Allergic Rhinitis and Asthma


Wednesday, March 02 | 9:20AM - 9:40AM
Coffee Break
Room: BC Foyer


Wednesday, March 02 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 1 of 9
* Bana Jabri, University of Chicago, USA


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 2 of 9
* De' Broski R. Herbert, University of Pennsylvania, USA


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 3 of 9
Paria Mirmonsef, Rush University Medical Center, USA
Activation of Mucosal Innate Immune Responses by Short Chain Fatty Acids and Toll-Like Receptor Ligands


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 4 of 9
Yuko Akiyama, University of Tokyo, Japan
Dual Role of Epithelial Fucosylation in the Small Intestine: Co-Habitation and Defense Niches for Commensal and Pathogenic Bacteria


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 5 of 9
Sin-Hyeog Im, POSTECH, South Korea
IRT5 Probiotics as an Immune Modulator for Diverse Immune Disorders


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 6 of 9
Gwo-Tzer Ho, University of Edinburgh, UK
Epithelial Multidrug Resistance-1 (MDR1) Gene Modulates Specific NF-kappaB-Response to Bacterial Flagellin and Promotes a Pro-Inflammatory Response in the Intestinal Epithelium


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 7 of 9
Mahima Swamy, London Research Institute, Cancer Research UK, UK
Understanding IEL Epithelium Interactions in the Gut


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 8 of 9
Lionel Le Bourhis, Institut Curie, France
Mucosal Associated Invariant T Cells Function in the Intestine


Wednesday, March 02 | 2:30PM - 4:30PM
Workshop 4: Epithelial Barrier Function and Bugs
This session is from Mucosal Biology
Room: British Ballroom

Speaker 9 of 9
Bjoern Ole Schroeder, Sahlgrenska Academy at University of Gothenburg, Sweden
Reduced to Action: Human beta defensin-1 in the Intestine


Wednesday, March 02 | 4:30PM - 5:00PM
Coffee Available
Room: BC Foyer


Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
Room: Columbia Ballroom

Speaker 1 of 4
* Kanta Subbarao, WHO Collaborating Centre for Reference and Research on Influenza, Australia
Local Immunity Induced by Live Attenuated Pandemic Influenza Vaccines

Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
Room: Columbia Ballroom

Speaker 2 of 4
Maytal Bivas-Benita, Beth Israel Deaconess Medical Center/Harvard Medical school, USA
Short Talk: Pulmonary DNA Immunization Generates Antigen-Specific CD8+T Cells in the Lung Airways that Protect Against Respiratory Lethal Viral Challenge

Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
Room: Columbia Ballroom

Speaker 3 of 4
Catharine M. Bosio, NIAID, National Institutes of Health, USA
Requirements for Immunity Against Pneumonic Tularemia

Wednesday, March 02 | 5:00PM - 7:00PM
Vaccines Inducing Pathogen-Specific Lung Immunity
Room: Columbia Ballroom

Speaker 4 of 4
* Jay K. Kolls, Tulane School of Medicine, USA
Balancing Mucosal Immunity in a Vaccine Context

Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy
This session is from Mucosal Biology

Room: British Ballroom

Speaker 1 of 4
* John D. Rioux, Montreal Heart Institute and Université de Montréal, Canada
What Genetic Studies Are Teaching Us about Mucosal Biology and Intestinal Inflammation


Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy
This session is from Mucosal Biology

Room: British Ballroom

Speaker 2 of 4
* Ludvig M. Sollid, University of Oslo, Norway
Autoimmune Dysregulation in Celiac Disease


Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy
This session is from Mucosal Biology

Room: British Ballroom

Speaker 3 of 4
Valerie Abadie, University of Chicago, USA
Short Talk: Co-Adjuvant Effects of Retinoic Acid and IL-15
Induce Inflammatory Immunity to Dietary Antigens


Wednesday, March 02 | 5:00PM - 7:00PM
Genetic and Molecular Basis of Intestinal Inflammation and A
llergy
This session is from Mucosal Biology

Room: British Ballroom

Speaker 4 of 4
Hugh A. Sampson, Icahn School of Medicine at Mount Sinai, USA
Treating Food Allergy


Wednesday, March 02 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pacific Ballroom


Wednesday, March 02 | 8:00PM - 11:00PM
Entertainment
Room: Pacific Ballroom


Wednesday, March 02 | 8:00PM - 11:00PM
Cash Bar
Room: Pacific Ballroom


Thursday, March 03 | 10:25AM - 10:25AM
Departure


*Session Chair.