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This meeting took place in the past. Here is a list of meetings that are related:
Mechanisms of Pro-Inflammatory Diseases (2015Z4)
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Web Desc
Rheumatoid Arthritis: Molecular and Clinical Insights
Organizer(s): David M. Lee, Gary S. Firestein and Ellen M. Gravallese
Date: January 19 - 24, 2012
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Organized with the support of the American College of Rheumatology Research and Education Foundation
Summary of Meeting:
Recent advances in genetic, cellular and molecular methodologies provide both new insights into disease pathogenesis and opportunities for therapeutic advances. Despite broad interest in rheumatoid arthritis (RA) within the immunology and clinical communities, there exists no focused venue for investigators with an interest in this disease to interact with each other, sharing ideas and developing productive collaborations. The Keystone Symposia format will fill this burgeoning need. This meeting will provide a venue for discussion of cutting-edge research topics in basic science and clinical science areas relevant to RA research. By fostering interactions between basic, translational and clinical investigators, we anticipate that this meeting will lead to new studies – as well as new approaches to studying – the pathogenesis and treatment of RA. The meeting will also serve to promote scientific development of early-career investigators, including those in training; their work will be among the selected presentations, creating an opportunity for interaction between junior investigators and outstanding senior scientists and mentors.
Scholarship Deadline: September 21 2011
Discounted Abstract Deadline: September 21 2011
Abstract Deadline: October 24 2011
Discounted Registration Deadline: November 21 2011
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
We gratefully acknowledge additional support for this conference from:
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:
Genentech, Inc.
Novartis Pharma AG
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
We gratefully acknowledge the generous grant for this conference provided by:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Grant No. 1R13AR061874-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:
Click here to view more of these organizations
Program
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Thursday, January 19
| 3:00PM - 7:30PM
Registration
Room: Zia Concourse
Thursday, January 19
| 6:15PM - 7:15PM
Refreshments
Room: Zia Concourse
Thursday, January 19
| 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Anasazi Ballroom
Speaker 1 of 4
David M. Lee
, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Introductory Remarks
Thursday, January 19
| 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Anasazi Ballroom
Speaker 2 of 4
Gary S. Firestein
, University of California, San Diego, USA
Moving the Field Forward: RA Research and Impact on Disease
Thursday, January 19
| 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Anasazi Ballroom
Speaker 3 of 4
* Ellen M. Gravallese
, University of Massachusetts Medical School, USA
Introduction of Keynote Speaker
Thursday, January 19
| 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Anasazi Ballroom
Speaker 4 of 4
William P. Arend
, University of Colorado School of Medicine, USA
Disease Mechanisms and Treatments: A Historic Benchtop to Bedside Perspective
Friday, January 20
| 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court
Friday, January 20
| 8:00AM - 11:00AM
Integrated Biology of the Joint in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 1 of 6
* Alisa Koch
, University of Michigan, USA
Friday, January 20
| 8:00AM - 11:00AM
Integrated Biology of the Joint in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 2 of 6
* William F. Rigby
, Dartmouth Medical School, USA
Friday, January 20
| 8:00AM - 11:00AM
Integrated Biology of the Joint in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 3 of 6
Michael B. Brenner
, Harvard Medical School, USA
Cadherin-11 Modulates Synovial Fibroblast Inflammation and Degradation
Friday, January 20
| 8:00AM - 11:00AM
Integrated Biology of the Joint in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 4 of 6
Gary S. Firestein
, University of California, San Diego, USA
Signaling Mechanisms in Synovial Inflammation
Friday, January 20
| 8:00AM - 11:00AM
Integrated Biology of the Joint in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 5 of 6
Ellen M. Gravallese
, University of Massachusetts Medical School, USA
Osteoclasts and Osteoblasts in Rheumatoid Arthritis
Friday, January 20
| 8:00AM - 11:00AM
Integrated Biology of the Joint in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 6 of 6
Georg Schett
, University of Erlangen-Nuremberg, Germany
Osteoimmunology: Cells and Factors that Impact Bone
Friday, January 20
| 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse
Friday, January 20
| 11:00AM - 1:00PM
Poster Setup
Room: Sunset Room
Friday, January 20
| 11:00AM - 11:00AM
On Own for Lunch and Recreation
Friday, January 20
| 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room
Friday, January 20
| 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse
Friday, January 20
| 5:00PM - 7:15PM
Innate Immunity in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 1 of 5
* Maripat P. Corr
, University of California, San Diego, USA
Friday, January 20
| 5:00PM - 7:15PM
Innate Immunity in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 2 of 5
Nina Bhardwaj
, Icahn School of Medicine at Mount Sinai, USA
Dendritic Cell-Mediated Modulation of Treg Function
Friday, January 20
| 5:00PM - 7:15PM
Innate Immunity in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 3 of 5
Peter A. Nigrovic
, Brigham and Women's Hospital, USA
Mast Cells in Arthritis: If, When and How
Friday, January 20
| 5:00PM - 7:15PM
Innate Immunity in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 4 of 5
David M. Lee
, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Platelets, Microvesicles and Inflammatory Synovitis
Friday, January 20
| 5:00PM - 7:15PM
Innate Immunity in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 5 of 5
Steffen Gay
, University Hospital Zürich, Switzerland
Epigenetics, microRNA and Innate Immunity
Friday, January 20
| 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room
Friday, January 20
| 7:30PM - 10:00PM
Poster Session 1
Room: Sunset Room
Saturday, January 21
| 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 1 of 8
* S. Louis Bridges, Jr.
, University of Alabama, Birmingham, USA
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 2 of 8
* Robert H. Carter
, NIAMS, National Institutes of Health, USA
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 3 of 8
Jennifer H. Anolik
, University of Rochester, USA
Autoantibody Dependent vs. Independent Roles for B Cells in RA
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 4 of 8
Gregg J. Silverman
, New York University Langone Medical Center, USA
Pathogenic and Protective Autoantibodies in Inflammatory Synovitis
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 5 of 8
Andrew C. Chan
, Genentech, Inc., USA
Redefining Human Disease to Meet the Challenges of Drug Discovery and Clinical Practice
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 6 of 8
David G. Winkler
, Infinity Pharmaceuticals, Inc., USA
Taking PI3Kdelta and PI3Kgamma for the Treatment of Immune-Mediated Inflammatory Diseases
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 7 of 8
Narendiran Rajasekaran
, Stanford University, USA
Short Talk: Host-Derived CD4+ T Cells Protect Lethally Irradiated B6.g7 Mice from Stem Cell Mediated Transfer of Autoimmunity
Saturday, January 21
| 8:00AM - 11:15AM
Autoimmunity I
Room: Anasazi Ballroom
Speaker 8 of 8
Safiehkhatoon Moshkani
, University of Rochester, USA
Short Talk: CD23+CD21High B Cells in Inflamed Lymph Nodes of TNF-Transgenic Mice Are a Locally Differentiated Population with Increased Antigen Capture and Activation Potential
Saturday, January 21
| 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse
Saturday, January 21
| 11:15AM - 1:00PM
Poster Setup
Room: Sunset Room
Saturday, January 21
| 11:15AM - 11:15AM
On Own for Lunch and Recreation
Saturday, January 21
| 1:00PM - 10:00PM
Poster Viewing
Room: Sunset Room
Saturday, January 21
| 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse
Saturday, January 21
| 5:00PM - 7:00PM
Systemic Disease in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 1 of 4
* William P. Arend
, University of Colorado School of Medicine, USA
Saturday, January 21
| 5:00PM - 7:00PM
Systemic Disease in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 2 of 4
Camilla I. Svensson
, Karolinska Institutet, Sweden
How Inflammatory Synovitis Produces Persistent Pain
Saturday, January 21
| 5:00PM - 7:00PM
Systemic Disease in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 3 of 4
Kevin L. Winthrop
, Oregon Health & Science University, USA
Anti-TNF Therapy and Beyond: Serious Infections and Mechanisms of Suppressed Host Defense in RA
Saturday, January 21
| 5:00PM - 7:00PM
Systemic Disease in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 4 of 4
Joan M. Bathon
, Columbia University, USA
Accelerated Atherosclerosis and Cardiovascular Disease
Saturday, January 21
| 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room
Saturday, January 21
| 7:30PM - 10:00PM
Poster Session 2
Room: Sunset Room
Sunday, January 22
| 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 1 of 8
* Hani El-Gabalawy
, University of Manitoba, Canada
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 2 of 8
*
Soumya Raychaudhuri
, Brigham and Women's Hospital, Harvard Medical School, USA
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 3 of 8
Dhavalkumar D. Patel
, UCB S.A., Belgium
Role of IL-17A in Rheumatoid Arthritis and Other Autoimmune Diseases.
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 4 of 8
V. Michael Holers
, University of Colorado Denver, USA
When Does RA Begin: Inflammatory and Autoimmune Signatures Precede Clinical Onset
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 5 of 8
David A. Fox
, University of Michigan Medical School, USA
Pathogenic and Protective T Cell Subsets in Rheumatoid Arthritis
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 6 of 8
William H. Robinson
, Stanford University School of Medicine, USA
Citrullination of Fibrinogen: Generation of Neoepitopes and Enhancement of Immunostimulatory Properties
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 7 of 8
Eric Boilard
, CRCHUQ, Universite Laval, Canada
Short Talk: Novel Platelet Function during Inflammatory Arthritis
Sunday, January 22
| 8:00AM - 11:15AM
Autoimmunity II
Room: Anasazi Ballroom
Speaker 8 of 8
Khaled Amara
, Karolinska Institutet, Sweden
Short Talk: Generation and Characterization of Monoclonal Antibodies from Single RA Synovial B Cells
Sunday, January 22
| 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse
Sunday, January 22
| 11:15AM - 11:15AM
On Own for Lunch and Recreation
Sunday, January 22
| 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse
Sunday, January 22
| 5:00PM - 7:00PM
Imaging and Biomarkers
Room: Anasazi Ballroom
Speaker 1 of 4
* Ingrid E. Lundberg
, Karolinska Institutet, Sweden
Sunday, January 22
| 5:00PM - 7:00PM
Imaging and Biomarkers
Room: Anasazi Ballroom
Speaker 2 of 4
Dennis McGonagle
, University of Leeds, St. James’s University Hospital, UK
From Pathogenesis to Disease Remission-How MRI and Ultrasound Have Transformed the Understanding of RA
Sunday, January 22
| 5:00PM - 7:00PM
Imaging and Biomarkers
Room: Anasazi Ballroom
Speaker 3 of 4
Michael L. Dustin
, University of Oxford, UK
In vivo Tracking of Regulatory T Cell Dynamics in Models of Autoimmune Disease
Sunday, January 22
| 5:00PM - 7:00PM
Imaging and Biomarkers
Room: Anasazi Ballroom
Speaker 4 of 4
Michael Centola
, Oklahoma Medical Research Foundation, USA
Utilizing Biomarkers of RA Disease Activity to Identify Patients at Risk of Joint Damage
Sunday, January 22
| 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room
Monday, January 23
| 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 1 of 7
* David R. Karp
, University of Texas Southwestern Medical Center, USA
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 2 of 7
* Erik J. Peterson
, University of Minnesota, USA
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 3 of 7
Iain B. McInnes
, University of Glasgow, UK
Therapeutic Opportunities in Innate Immunity in Inflammatory Arthritis
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 4 of 7
Soumya Raychaudhuri
, Brigham and Women's Hospital, Harvard Medical School, USA
Translating Rheumatoid Arthritis Genetic Loci into Pathogenic Processes
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 5 of 7
Lars Klareskog
, Karolinska Institutet, Sweden
Susceptibility Is More Than Our Genes: Roles of Environment and Genes in Triggering Disease-Related Autoimmunity
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 6 of 7
Robert M. Plenge
, Celgene, USA
'The Cycle' of Discovery Research in Rheumatoid Arthritis: Integrating Next-Generation Genomics with Next-Generation Clinical Data from Electronic Health Records
Monday, January 23
| 8:00AM - 11:15AM
Omics and Informatics
Room: Anasazi Ballroom
Speaker 7 of 7
Ronald N. Germain
, NIAID, National Institutes of Health, USA
A New Omics: System-Wide Analysis of the Human Immune System in Health and Disease
Monday, January 23
| 9:00AM - 9:20AM
Coffee Break
Room: Zia Concourse
Monday, January 23
| 10:00AM - 10:00AM
On Own for Lunch and Recreation
Monday, January 23
| 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse
Monday, January 23
| 5:00PM - 7:00PM
Clinical Developments in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 1 of 4
Michael J. Townsend
, Genentech, Inc, USA
Short Talk: Rheumatoid Arthritis Patients Possess Distinct Molecular and Cellular Synovial Phenotypes that Impact Clinical Outcome
Monday, January 23
| 5:00PM - 7:00PM
Clinical Developments in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 2 of 4
Cécile T. J. Holweg
, Genentech, Inc., USA
Short Talk: Pretreatment Synovial Transcriptional Profile Correlates with Early and Late Clinical Response in Rheumatoid Arthritis Patients Treated with Rituximab
Monday, January 23
| 5:00PM - 7:00PM
Clinical Developments in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 3 of 4
Eric M. Ruderman
, Northwestern University, USA
Placebos, Active Comparators and Creative Trial Design in RA
Monday, January 23
| 5:00PM - 7:00PM
Clinical Developments in Rheumatoid Arthritis
Room: Anasazi Ballroom
Speaker 4 of 4
* E. William St. Clair
, Duke University Medical Center, USA
Therapeutic Targeting of Adaptive Immunity in Rheumatoid Arthritis: Successes and Limitations
Monday, January 23
| 7:00PM - 7:05PM
Closing Remarks
Room: Anasazi Ballroom
Speaker 1 of 3
David M. Lee
, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Monday, January 23
| 7:00PM - 7:05PM
Closing Remarks
Room: Anasazi Ballroom
Speaker 2 of 3
Gary S. Firestein
, University of California, San Diego, USA
Monday, January 23
| 7:00PM - 7:05PM
Closing Remarks
Room: Anasazi Ballroom
Speaker 3 of 3
Ellen M. Gravallese
, University of Massachusetts Medical School, USA
Monday, January 23
| 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Eldorado Court/Sunset Room
Monday, January 23
| 8:00PM - 11:00PM
Entertainment
Room: Eldorado Court/Sunset Room
Monday, January 23
| 8:00PM - 11:00PM
Cash Bar
Room: Eldorado Court/Sunset Room
Tuesday, January 24
| 10:25AM - 10:25AM
Departure
*Session Chair.
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