Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Phenotypic Drug Discovery: Recent Advances and Insights from Chemical and Systems Biology (2019C1)

Web Desc
Chemical Biology and Novel Tools in Pharmacology Organizer(s): Laura L. Kiessling, Kevan M. Shokat and Jason E. Gestwicki Date: February 12 - 16, 2012 Location: Hilton Santa Fe Historic Plaza Hotel, Santa Fe, NM, USA Sponsored by Infinity Pharmaceuticals, Novartis Institutes for BioMedical Research and Onyx Pharmaceuticals, Inc. For important information on the coronavirus, please click here Summary of Meeting: The best solutions to the most important problems in biomedical science have come from multi-disciplinary research. The discovery of new chemical probes and therapeutics requires cross-cutting expertise and the innovative application of new technologies. Scientific forums have become increasingly specialized and narrow in their scope. The specific purpose of the Keystone Symposia meeting on Chemical Biology and Novel Tools in Pharmacology is to initiate and foster active discussions between academic and industrial researchers in the broader area of pharmacological tools. Rather than focus on a specific disease, model system or technical method, this meeting will bring together a variety of experts whose primary, common trait is their innovative use of chemical and biological approaches to solve important problems in biology. From this organizing principle, the specific aims of this meeting are: (a) to assemble chemists and biologists who may not normally interact with each other; (b) to make new connections between chemists and biologists, academics and industrial scientists; and (c) to provide a forum for an open discourse of modern, cross-platform ideas. An unintended consequence of increasingly specialized forums for scientific discussion is the lack of mechanisms for dissemination of novel ideas, platforms and methodologies. The major innovation of this meeting is that it is designed to encourage and inspire researchers to explore and implement inter-disciplinary, emerging methods in chemical biology and pharmacology to their specific biological questions. Scholarship Deadline: October 12 2011 Discounted Abstract Deadline: October 12 2011 Abstract Deadline: November 11 2011 Discounted Registration Deadline: December 12 2011 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: ACS Chemical Biology Laura L. Kiessling, Ronald T. Raines We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of General Medical Sciences (NIGMS) Grant No. 1R13GM100628-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Chemical Biology and Novel Tools in Pharmacology

Organizer(s): Laura L. Kiessling, Kevan M. Shokat and Jason E. Gestwicki

Date: February 12 - 16, 2012
Location: Hilton Santa Fe Historic Plaza Hotel, Santa Fe, NM, USA

Sponsored by Infinity Pharmaceuticals, Novartis Institutes for BioMedical Research and Onyx Pharmaceuticals, Inc.

For important information on the coronavirus, please click here

Summary of Meeting:

The best solutions to the most important problems in biomedical science have come from multi-disciplinary research. The discovery of new chemical probes and therapeutics requires cross-cutting expertise and the innovative application of new technologies. Scientific forums have become increasingly specialized and narrow in their scope. The specific purpose of the Keystone Symposia meeting on Chemical Biology and Novel Tools in Pharmacology is to initiate and foster active discussions between academic and industrial researchers in the broader area of pharmacological tools. Rather than focus on a specific disease, model system or technical method, this meeting will bring together a variety of experts whose primary, common trait is their innovative use of chemical and biological approaches to solve important problems in biology. From this organizing principle, the specific aims of this meeting are: (a) to assemble chemists and biologists who may not normally interact with each other; (b) to make new connections between chemists and biologists, academics and industrial scientists; and (c) to provide a forum for an open discourse of modern, cross-platform ideas. An unintended consequence of increasingly specialized forums for scientific discussion is the lack of mechanisms for dissemination of novel ideas, platforms and methodologies. The major innovation of this meeting is that it is designed to encourage and inspire researchers to explore and implement inter-disciplinary, emerging methods in chemical biology and pharmacology to their specific biological questions.

Scholarship Deadline: October 12 2011

Discounted Abstract Deadline: October 12 2011

Abstract Deadline: November 11 2011

Discounted Registration Deadline: December 12 2011

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

ACS Chemical Biology

Laura L. Kiessling, Ronald T. Raines

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of General Medical Sciences (NIGMS)
Grant No. 1R13GM100628-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, February 12 \| 3:00PM - 7:30PM Registration Room: Promenade
Sunday, February 12 \| 6:15PM - 7:15PM Refreshments Room: Promenade
Sunday, February 12 \| 7:15PM - 8:30PM Welcome and Keynote Address Room: Mesa A-B Speaker 1 of 1 Christopher T. Walsh, Harvard Medical School, USA Biosynthetic Morphing of Peptide Backbones and Side Chains into Heterocyclic Scaffolds
Monday, February 13 \| 7:00AM - 8:00AM Breakfast Room: Chamisa/Ortiz
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 1 of 7 * Ronald W. Woodard, University of Michigan, USA
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 2 of 7 Nathan A. Magarvey, McMaster University, Canada Mining Microbiomes for Genetically Encoded Bioactive Natural Products
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 3 of 7 Stephen B. del Cardayre, LS9, Inc., USA Engineering Microbial Fatty Acid Metabolism for Sustainable Fuel and Chemical Production
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 4 of 7 Suzanne Walker, Harvard Medical School, USA Cell Biology and Enzymology of Cell Wall Biosynthesis
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 5 of 7 Laura L. Kiessling, Massachusetts Institute of Technology, USA The Chemistry and Biology of Mycobacterial Polysaccharide Assembly
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 6 of 7 Douglas B. Weibel, Amazon.com, Inc., USA Short Talk: Bacteria Control Intracellular Organization by Straining Their Cytoplasmic Membrane
Monday, February 13 \| 8:00AM - 11:15AM Chemical Microbiology Room: Mesa A-B Speaker 7 of 7 Howard C. Hang, Rockefeller University, USA Short Talk: Chemical Reporters for Dissecting Host-Pathogen Interactions
Monday, February 13 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Monday, February 13 \| 11:15AM - 1:00PM Poster Setup Room: Mesa C
Monday, February 13 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Monday, February 13 \| 1:00PM - 10:00PM Poster Viewing Room: Mesa C
Monday, February 13 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Monday, February 13 \| 5:00PM - 6:25PM Chemical Communication I Room: Mesa A-B Speaker 1 of 4 * Susan L. Clugston, Cubist Pharmaceuticals, USA
Monday, February 13 \| 5:00PM - 6:25PM Chemical Communication I Room: Mesa A-B Speaker 2 of 4 Sean Cutler, University of California, Riverside, USA Sidestepping Genetic Redundancy with Small Molecules
Monday, February 13 \| 5:00PM - 6:25PM Chemical Communication I Room: Mesa A-B Speaker 3 of 4 Cameron R. Currie, University of Wisconsin-Madison, USA Drugs from Bugs of Bugs
Monday, February 13 \| 5:00PM - 6:25PM Chemical Communication I Room: Mesa A-B Speaker 4 of 4 Erin E. Carlson, Indiana University, USA Short Talk: Chemical Probes to Explore Histidine Kinase Signaling
Monday, February 13 \| 6:25PM - 7:00PM Probing and Perturbing Cell Signaling I Room: Mesa A-B Speaker 1 of 1 Timothy J. Mitchison, Harvard Medical School, USA How Does Taxol Work as a Medicine?
Monday, February 13 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Chamisa/Ortiz
Monday, February 13 \| 7:30PM - 10:00PM Poster Session 1 Room: Mesa C
Tuesday, February 14 \| 7:00AM - 8:00AM Breakfast Room: Chamisa/Ortiz
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 1 of 7 * Sharon Xiaoning Zhao, Amgen Inc, USA
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 2 of 7 Carsten Schultz, European Molecular Biology Laboratory Heidelberg, Germany Tools for Visualizing Cell Biology
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 3 of 7 Jing Huang, University of California, Los Angeles, USA Small Molecule Regulators of Aging
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 4 of 7 Tom W. Muir, Princeton University, USA Protein Ligation: An Enabling Technology for Studying Protein Post-Translational Modifications
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 5 of 7 Kevan M. Shokat, University of California, San Francisco, USA Chemical-Genetic Investigations of Protein and Lipid Kinase Signaling
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 6 of 7 Matthew R. Pratt, University of Southern California, USA Short Talk: O-GlcNAc as a Link Between Metabolism and Survival in Cancer
Tuesday, February 14 \| 8:00AM - 11:15AM Probing and Perturbing Cell Signaling II Room: Mesa A-B Speaker 7 of 7 Morgan Huse, Memorial Sloan Kettering Cancer Center, USA Short Talk: A Photochemical Approach to Lymphocyte Signaling Dynamics
Tuesday, February 14 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Tuesday, February 14 \| 11:15AM - 1:00PM Poster Setup Room: Mesa C
Tuesday, February 14 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, February 14 \| 1:00PM - 10:00PM Poster Viewing Room: Mesa C
Tuesday, February 14 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Tuesday, February 14 \| 5:00PM - 7:00PM Protein Quality Control Room: Mesa A-B Speaker 1 of 6 * Susan Wiedner, Pacific Northwest National Laboratory, USA
Tuesday, February 14 \| 5:00PM - 7:00PM Protein Quality Control Room: Mesa A-B Speaker 2 of 6 Jason E. Gestwicki, University of California, San Francisco, USA Molecular Chaperones and Protein Folding: Chemical Tools for Probing Quality Control
Tuesday, February 14 \| 5:00PM - 7:00PM Protein Quality Control Room: Mesa A-B Speaker 3 of 6 Julian Adams, Vedantra Pharmaceuticals, Inc., USA Natural Product-Derived Inhibitor of the Hedgehog Pathway and Clinical Development to Treat Cancer
Tuesday, February 14 \| 5:00PM - 7:00PM Protein Quality Control Room: Mesa A-B Speaker 4 of 6 Raquel L. Lieberman, Georgia Institute of Technology, USA Short Talk: Pharmacological Chaperone Development for the Glaucoma-Associated Olfactomedin Domain of Myocilin
Tuesday, February 14 \| 5:00PM - 7:00PM Protein Quality Control Room: Mesa A-B Speaker 5 of 6 Eric R. Strieter, University of Wisconsin, USA Short Talk: Non-Enzymatic Synthesis of Polyubiquitin Chains
Tuesday, February 14 \| 5:00PM - 7:00PM Protein Quality Control Room: Mesa A-B Speaker 6 of 6 Kurt Dwaine Deshayes, Genentech, Inc., USA Short Talk: Peptide Sensors of Angiogenesis
Tuesday, February 14 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Chamisa/Ortiz
Tuesday, February 14 \| 8:00PM - 10:00PM Poster Session 2 Room: Mesa C
Wednesday, February 15 \| 7:00AM - 8:00AM Breakfast Room: Chamisa/Ortiz
Wednesday, February 15 \| 8:00AM - 10:25AM Probing and Perturbing Cell Signaling III Room: Mesa A-B Speaker 1 of 5 * Alison N. Hulme, University of Edinburgh, UK
Wednesday, February 15 \| 8:00AM - 10:25AM Probing and Perturbing Cell Signaling III Room: Mesa A-B Speaker 2 of 5 Ulrike S. Eggert, King's College London, UK A Chemical Approach to Understanding Cell Division
Wednesday, February 15 \| 8:00AM - 10:25AM Probing and Perturbing Cell Signaling III Room: Mesa A-B Speaker 3 of 5 Rebecca W. Heald, University of California, Berkeley, USA Importazole, a Small Molecule Inhibitor of the Transport Receptor Importin-beta
Wednesday, February 15 \| 8:00AM - 10:25AM Probing and Perturbing Cell Signaling III Room: Mesa A-B Speaker 4 of 5 Luke D. Lavis, HHMI/Janelia Farm Research Campus, USA Short Talk: Targeting Small Molecules with Cellular Specificity using Enzyme–Substrate Pairs
Wednesday, February 15 \| 8:00AM - 10:25AM Probing and Perturbing Cell Signaling III Room: Mesa A-B Speaker 5 of 5 E. James Petersson, University of Pennsylvania, USA Short Talk: Thioamides: Minimalist Chromophores for Monitoring Protein Dynamics In Vitro and In Vivo
Wednesday, February 15 \| 9:20AM - 9:40AM Coffee Break Room: Promenade
Wednesday, February 15 \| 10:25AM - 11:00AM Chemical Communication II Speaker 1 of 1 John W. Kozarich, ActivX Biosciences, Inc., USA Toward a Functional, Chemoproteomic Interrogation of Kinome and Nucleotide Binding Space
Wednesday, February 15 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Wednesday, February 15 \| 4:30PM - 5:00PM Coffee Available Room: Promenade
Wednesday, February 15 \| 5:00PM - 7:15PM Chemical Biology in Model Organisms Room: Mesa A-B Speaker 1 of 5 * Jeffrey P. Henderson, Center for Women's Infectious Diseases Research, Washington University, USA
Wednesday, February 15 \| 5:00PM - 7:15PM Chemical Biology in Model Organisms Room: Mesa A-B Speaker 2 of 5 Charlie M. Boone, University of Toronto, Canada Linking Bioactive Compounds to Cellular Targets by High-Throughput Chemical-Genetic Profiling in Yeast
Wednesday, February 15 \| 5:00PM - 7:15PM Chemical Biology in Model Organisms Room: Mesa A-B Speaker 3 of 5 Frank C. Schroeder, Boyce Thompson Institute at Cornell University, USA C. elegans Ascarosides, a Modular Library of Small Molecule Signals
Wednesday, February 15 \| 5:00PM - 7:15PM Chemical Biology in Model Organisms Room: Mesa A-B Speaker 4 of 5 Carolyn R. Bertozzi, Stanford University, USA Bioorthogonal Chemistry for Glycoprofiling and Beyond
Wednesday, February 15 \| 5:00PM - 7:15PM Chemical Biology in Model Organisms Room: Mesa A-B Speaker 5 of 5 Jeffery W. Kelly, The Scripps Research Institute, USA Adapting Proteostasis to Ameliorate Aggregation-Associated Gain-of-Toxic Function Diseases and Developing Folding and Aggregation Sensors of these Maladies
Wednesday, February 15 \| 8:15PM - 9:15PM Social Hour with Lite Bites Room: Mesa Ballroom
Wednesday, February 15 \| 8:15PM - 11:00PM Entertainment Room: Mesa Ballroom
Wednesday, February 15 \| 9:15PM - 11:00PM Cash Bar Room: Mesa Ballroom
Thursday, February 16 \| 10:23AM - 10:23AM Departure *Session Chair †Invited, not yet responded.