Web Desc
Advances in Islet Biology
Organizer(s): Lori Sussel, Jorge Ferrer and Andrew F. Stewart
Date: March 25 - 30, 2012
Location: Portola Hotel & Spa, Monterey, California, USA
Sponsored by Merck & Co., Inc. and Sanofi US
For important information on the coronavirus, please click here
Summary of Meeting:
During the past 10 to 15 years, there has been significant progress in our understanding of pancreatic islet development and islet biology. This knowledge has been complemented and accelerated by major advances in diverse fields including islet transplantation, stem cells, small molecule screening, high-throughput sequencing, epigenetics and human genetics. The integration of these divergent disciplines has allowed us to develop a clearer definition of a functional b cell and has elucidated many of the mechanisms underlying the differentiation, survival and death of the b cell. Furthermore, these studies have revealed the potential to generate new b cells through replication or neogenesis. Improvements in differentiation and transdifferentiation protocols have also illustrated the potential of using stem cells and some somatic cell types as sources of islet cells, but these studies have also revealed the challenges associated with generating functional b cells. The purpose of this Keystone Symposia meeting is to highlight the areas of islet biology that have seen the most remarkable advances and to address some of the controversies that still exist in the field, especially with regards to the generation and maintenance of functionally mature b cells for therapeutic purposes. In addition, where it is possible, comparative mouse and human studies will be discussed to illustrate if and when mouse studies can be applied to the human situation.
Scholarship Deadline: November 22 2011
Discounted Abstract Deadline: November 22 2011
Abstract Deadline: January 3 2012
Discounted Registration Deadline: January 25 2012
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Merck & Co., Inc.Sanofi US
We gratefully acknowledge additional support for this conference from:
ALPCO DiagnosticsJDRFMercodia, Inc.ViaCyte, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genomics Institute of the Novartis Research Foundation

ViaCyte, Inc.


Peter Strop
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK084688-03
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 25 | 3:00PM - 7:30PM
Registration
Room: De Anza Foyer


Sunday, March 25 | 6:15PM - 7:15PM
Refreshments
Room: De Anza Foyer


Sunday, March 25 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Steinbeck Forum

Speaker 1 of 2
* Jorge Ferrer, Imperial College London, UK

Sunday, March 25 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Steinbeck Forum

Speaker 2 of 2
Andrew Hattersley, University of Exeter Medical School, UK
The Genetics of Diabetes: Understanding Inherited Beta Cell Defects

Monday, March 26 | 7:30AM - 8:30AM
Breakfast
Room: De Anza 1-3


Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 1 of 7
* Matthias Hebrok, University of California, San Francisco, USA

Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 2 of 7
Ludovic Vallier, Wellcome Trust Sanger Institute, UK
Signaling Pathways Controlling Differentiation of Human Endoderm Cells

Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 3 of 7
Paul Gadue, Children's Hospital of Philadelphia, USA
Generation of Self-Renewing Endodermal Stem Cells with the Potential to Produce Functional Beta Cells in vitro

Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 4 of 7
M. Cristina Nostro, University Health Network, Canada
Short Talk: Human Embryonic Stem Cell-derived INSULIN-expressing Cells Generate alpha-like Cells in vivo

Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 5 of 7
Kevin A. D'Amour, ViaCyte, Inc., USA
Development of an Encapsulated Stem-Cell Therapy for Insulin-Dependent Diabetes

Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 6 of 7
Raphael Scharfmann, INSERM, France
Pancreatic Beta Cell Development: Experimental Models to Transfer Data from Rodent to Human

Monday, March 26 | 8:30AM - 11:45AM
Stem Cells as a Source of Islet Cells
Room: Steinbeck Forum

Speaker 7 of 7
Diego Balboa, Centre for Genomic Regulation, Spain
Short Talk: Directed Differentiation of Patient-Specific iPS Cells to Model Permanent Neonatal Diabetes Mellitus

Monday, March 26 | 9:40AM - 10:00AM
Coffee Break
Room: De Anza Foyer


Monday, March 26 | 11:45AM - 1:00PM
Poster Setup
Room: De Anza 1-3


Monday, March 26 | 11:45AM - 11:45AM
On Own for Lunch and Recreation


Monday, March 26 | 1:00PM - 10:00PM
Poster Viewing
Room: De Anza 1-3


Monday, March 26 | 4:30PM - 5:00PM
Coffee Available
Room: De Anza Foyer


Monday, March 26 | 5:00PM - 7:15PM
Mechanisms of Beta Cell Replication
Room: Steinbeck Forum

Speaker 1 of 6
* Anil Bhushan, University of California, San Francisco, USA

Monday, March 26 | 5:00PM - 7:15PM
Mechanisms of Beta Cell Replication
Room: Steinbeck Forum

Speaker 2 of 6
Andrew F. Stewart, Mount Sinai School of Medicine, USA
Induction of Proliferation in Human beta Cells for Diabetes

Monday, March 26 | 5:00PM - 7:15PM
Mechanisms of Beta Cell Replication
Room: Steinbeck Forum

Speaker 3 of 6
Seung K. Kim, Stanford University, USA
Regulation of Pancreatic Beta Cell Growth and Maturation

Monday, March 26 | 5:00PM - 7:15PM
Mechanisms of Beta Cell Replication
Room: Steinbeck Forum

Speaker 4 of 6
Jean-Sébastien Annicotte, EGID CNRS UMR 8199, France
Short Talk: An E2F1-CDK4-CDKN2A Pathway Controlling beta-Cell Proliferation and Function

Monday, March 26 | 5:00PM - 7:15PM
Mechanisms of Beta Cell Replication
Room: Steinbeck Forum

Speaker 5 of 6
Ernesto Bernal-Mizrachi, University of Miami Miller School of Medicine, USA
Integration of PI3K, mTor and GSK3beta Signaling with Pancreatic Beta Cell Replication

Monday, March 26 | 5:00PM - 7:15PM
Mechanisms of Beta Cell Replication
Room: Steinbeck Forum

Speaker 6 of 6
Jeffery S. Tessem, Brigham Young University, USA
Short Talk: Nkx6.1 Mediated beta Cell Proliferation Pathways

Monday, March 26 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: De Anza 1-3


Monday, March 26 | 7:30PM - 10:00PM
Poster Session 1
Room: De Anza 1-3


Tuesday, March 27 | 7:30AM - 8:30AM
Breakfast
Room: De Anza 1-3


Tuesday, March 27 | 7:30AM - 8:30PM
Poster Setup
Room: De Anza 1-3


Tuesday, March 27 | 8:30AM - 5:00PM
Poster Viewing
Room: De Anza 1-3


Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 1 of 7
* Lori Sussel, University of Colorado Anschutz Medical Campus, USA

Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 2 of 7
Domenico Accili, Columbia University, USA
Generation of Functional Insulin-Producing Cells in the Gut by Foxo1 Ablation

Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 3 of 7
Matthias Hebrok, University of California, San Francisco, USA
Cellular Plasticity in the Pancreas

Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 4 of 7
Chris Wright, Vanderbilt University Medical Center, USA
Lineage Interconversion between Pancreas Cell Types in Combined Injury and Pdx1 Overexpression Models

Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 5 of 7
Judsen D. Schneider, Vanderbilt University Medical Center, USA
Short Talk: Ngn3 Reprograms Acinar Cells into Endocrine Cells

Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 6 of 7
Christine A. Beamish, Houston Methodist Research Institute, USA
Short Talk: Rare Transition of Mouse beta-Cells to Duct-Like Cells in vitro: beta-Cell Differentiation or Activation of Insulin+ Precursors?

Tuesday, March 27 | 8:30AM - 11:45AM
Reprogramming
Room: Steinbeck Forum

Speaker 7 of 7
Luc Baeyens, Free University Brussels, Belgium
Cytokines that Protect and Regenerate Functional Beta Cells to Normalize Hyperglycemia in Mice

Tuesday, March 27 | 9:40AM - 10:00AM
Coffee Break
Room: De Anza Foyer


Tuesday, March 27 | 10:00AM - 10:00AM
On Own for Dinner


Tuesday, March 27 | 11:45AM - 12:30PM
Lunch
Room: De Anza 1-3


Tuesday, March 27 | 12:00PM - 2:30PM
Poster Session 2
Room: De Anza 1-3


Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 1 of 9
* George K. Gittes, Children's Hospital of Pittsburgh of UPMC, USA

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 2 of 9
Zhiguang Guo, Sanford Research/USD, USA
Targeting GPR119 to Stimulate beta-Cell Regeneration

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 3 of 9
Elina Hakonen, University of Helsinki, Finland
Conditional Expression of a Constitutively Active EGF-R in beta Cells Protects Against Streptozotocin-Induced Diabetes

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 4 of 9
Tatsuyoshi M. Kono, Indiana University School of Medicine, USA
Rescue of SERCA2B Expression Improves Pancreatic beta Cell Proliferation and Survival in Type 2 Diabetes Mellitus

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 5 of 9
Mette V. Jensen, Duke University Medical Center, USA
Pyruvate-Isocitrate Cycling Regulates Expression of Kv2.2 and Glucose-Stimulated Insulin Secretion

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 6 of 9
Alan Schneyer, University of Massachusetts, Amherst, USA
Role of Activin and FSTL3 in alpha- and beta-Cell Expansion/TransDifferentiation

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 7 of 9
Yousef El-Gohary, Children's Hospital of Pittsburgh, USA
Smad Signaling Plays a Key Role in Regulating Islet Cell Proliferation and Development


Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 8 of 9
Jens Høiriis Nielsen, University of Copenhagen, Denmark
Identification of Circulating Factors that may be Involved in Beta Cell Adaptation to Pregnancy

Tuesday, March 27 | 2:30PM - 4:30PM
Workshop 1: Signaling Pathways Influencing the Adult Islet
Room: Steinbeck Forum

Speaker 9 of 9
Patricia Ducy, Columbia University, USA
Regulation of Perinatal beta-Cell Proliferation by Osteocalcin Signaling

Tuesday, March 27 | 4:30PM - 5:00PM
Coffee Available
Room: De Anza Foyer


Tuesday, March 27 | 5:00PM - 7:15PM
Epigenetics of the Islet Cell
Room: Steinbeck Forum

Speaker 1 of 6
* Yuval Dor, Hebrew University-Hadassah Medical School, Israel

Tuesday, March 27 | 5:00PM - 7:15PM
Epigenetics of the Islet Cell
Room: Steinbeck Forum

Speaker 2 of 6
Jorge Ferrer, Imperial College London, UK
Long Non-Coding Transcripts in Human Islet Cells

Tuesday, March 27 | 5:00PM - 7:15PM
Epigenetics of the Islet Cell
Room: Steinbeck Forum

Speaker 3 of 6
Klaus H. Kaestner, University of Pennsylvania School of Medicine, USA
Global Epigenetic Analysis of Pancreatic Islet Cells

Tuesday, March 27 | 5:00PM - 7:15PM
Epigenetics of the Islet Cell
Room: Steinbeck Forum

Speaker 4 of 6
Anil Bhushan, University of California, San Francisco, USA
Epigenetic Mechanisms that Regulate Pancreatic beta Cell Identity

Tuesday, March 27 | 5:00PM - 7:15PM
Epigenetics of the Islet Cell
Room: Steinbeck Forum

Speaker 5 of 6
Michael L. Stitzel, The Jackson Laboratory for Genomic Medicine, USA
Short Talk: Cis-Regulatory Variation in Islet Dysfunction and Diabetes

Tuesday, March 27 | 5:00PM - 7:15PM
Epigenetics of the Islet Cell
Room: Steinbeck Forum

Speaker 6 of 6
Philippe Ravassard, Institut du Cerveau et de la Moelle, France
Short Talk: A Long-Range Cell Type-Specific Enhancer of Neurog3 Acts as a Polycomb Response Element in vivo

Wednesday, March 28 | 7:30AM - 8:30AM
Breakfast
Room: De Anza 1-3


Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 1 of 7
* Fred Levine, Sanford-Burnham Medical Research Institute, USA

Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 2 of 7
Matthias G. von Herrath, Novo Nordisk and La Jolla Institute for Allergy and Immunology, USA
Novel Insights into the Immunopathogenesis of Human Type 1 Diabetes

Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 3 of 7
Gerald T. Nepom, Benaroya Research Institute, USA
Therapeutic Options in Type 1 Diabetic Patients

Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 4 of 7
Dale L. Greiner, University of Massachusetts Medical School, USA
Humanized Mice for the Study of Diabetes

Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 5 of 7
Pere Santamaria, University of Calgary, Canada
The beta-Cell Regenerative Capacity of the Diabetic NOD Pancreas Upon Reversal of Autoimmunity

Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 6 of 7
Midhat H. Abdulreda, Diabetes Research Institute, USA
Short Talk: In vivo Non-Invasive Imaging of the Immunopathology of Type 1 Diabetes in NOD Mice

Wednesday, March 28 | 8:30AM - 11:45AM
Immunopathology of Type 1 Diabetes
Room: Steinbeck Forum

Speaker 7 of 7
Scott A. Soleimanpour, University of Michigan Medical School, USA
Short Talk: Clec16a, a T1DM Susceptibility Gene and Novel Pdx1 Target, Regulates Endosomal and Mitochondrial Function in Min6 beta-Cells

Wednesday, March 28 | 9:40AM - 10:00AM
Coffee Break
Room: De Anza Foyer


Wednesday, March 28 | 11:45AM - 1:00PM
Poster Setup
Room: De Anza 1-3


Wednesday, March 28 | 11:45AM - 11:45AM
On Own for Lunch and Recreation


Wednesday, March 28 | 1:00PM - 10:00PM
Poster Viewing
Room: De Anza 1-3


Wednesday, March 28 | 4:30PM - 5:00PM
Coffee Available
Room: De Anza Foyer


Wednesday, March 28 | 5:00PM - 7:15PM
Cell-Cell Communications Influencing the Endocrine Pancreas
Room: Steinbeck Forum

Speaker 1 of 5
Ondine Cleaver, University of Texas Southwestern Medical Center, USA
The Role of Vasculature in Regulation of Islet Cell Differentiation

Wednesday, March 28 | 5:00PM - 7:15PM
Cell-Cell Communications Influencing the Endocrine Pancreas
Room: Steinbeck Forum

Speaker 2 of 5
Vincenzo Cirulli, University of Washington, USA
Cell-Cell and Cell-Matrix Interactions as Instructive Cues for Developing Islet Progenitors

Wednesday, March 28 | 5:00PM - 7:15PM
Cell-Cell Communications Influencing the Endocrine Pancreas
Room: Steinbeck Forum

Speaker 3 of 5
Peter W. Zandstra, University of British Columbia, Canada
Synthetic Stem Cell Niche Engineering to Control Endoderm Development and Pancreatic Maturation

Wednesday, March 28 | 5:00PM - 7:15PM
Cell-Cell Communications Influencing the Endocrine Pancreas
Room: Steinbeck Forum

Speaker 4 of 5
Rachel B. Reinert, Vanderbilt University Medical Center, USA
Short Talk: VEGF-A Directs Autonomic Innervation of the Pancreatic Islet

Wednesday, March 28 | 5:00PM - 7:15PM
Cell-Cell Communications Influencing the Endocrine Pancreas
Room: Steinbeck Forum

Speaker 5 of 5
David A. Cano, Institute of Biomedicine of Seville, Spain
Short Talk: Role of Glial Cell Line-Derived Neurotrophic Factor in Embryonic Pancreas Colonization by Neural Precursors

Wednesday, March 28 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: De Anza 1-3


Wednesday, March 28 | 7:30PM - 10:00PM
Poster Session 3
Room: De Anza 1-3


Thursday, March 29 | 7:30AM - 8:30AM
Breakfast
Room: De Anza 1-3


Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 1 of 7
* Andrew F. Stewart, Mount Sinai School of Medicine, USA

Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 2 of 7
Bridget Wagner, Broad Institute, USA
High-Throughput Screening for Small Molecules to Increase Beta-Cell Mass

Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 3 of 7
Bryan A. Laffitte, Genomics Institute of the Novartis Research Foundation, USA
Approaches to Beta Cell Regeneration and Survival in Type-1 Diabetes

Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 4 of 7
Yuval Dor, Hebrew University-Hadassah Medical School, Israel
Mechanisms of Pancreatic Beta Cell Regeneration

Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 5 of 7
David J. Hill, St. Joseph's Hospital, Canada
Pathways to Regeneration: Statins, Augurin and Immunization with Myobacterial Adjuvant

Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 6 of 7
Fred Levine, Sanford-Burnham Medical Research Institute, USA
Short Talk: Induction of beta-Cell Replication by an HNF4a Antagonist

Thursday, March 29 | 8:30AM - 11:45AM
Novel Therapeutic Targets
Room: Steinbeck Forum

Speaker 7 of 7
Olov Andersson, Karolinska Institutet, Sweden
Short Talk: A Chemical Screen in Zebrafish Identifies Adenosine Signaling as a Promoter of Pancreatic Beta-Cell Regeneration

Thursday, March 29 | 9:40AM - 10:00AM
Coffee Break
Room: De Anza Foyer


Thursday, March 29 | 11:45AM - 11:45AM
On Own for Lunch and Recreation


Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 1 of 9
* Catherine Lee May, University of Pennsylvania, USA

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 2 of 9
Brandon L. Taylor, Genomics Institute of the Novartis Research Foundation, USA
Nkx6.1 is Required for Maintenance of beta Cells and beta Cell Function

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 3 of 9
Ja Young Kim-Muller, Pfizer Inc, USA
Triple FoxO Knockout (1, 3a, and 4) in beta-Cells Impairs Glucose-Induced Insulin Secretion and Causes Hyperglycemia

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 4 of 9
Arun Sharma, MedImmune, USA
MafA Expression is Sufficient to Overcome beta-Cell Dysfunction in Pdx1 Haplo-Insufficient Mice

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 5 of 9
Bryan O'Sullivan-Murphy, Fumi Urano/LRB-522 - University of Massachusetts Medical School, USA
WFS1 Allelic Variants Enhance beta Cell Viability and Function

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 6 of 9
Lukas Adrian Berchtold, University of Copenhagen, Denmark
An Integrative Network-Based Approach Identifies Pannexin2 as an Anti-Apoptotic Protein in Pancreatic beta Cells

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 7 of 9
Young-mi Song, Yonsei University, South Korea
Inhibition of Autophagy by Increase of ER Stress through Glycated Albumin(GA)-Induced ROS Increases Apoptosis

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 8 of 9
Mark O. Huising, University of California, Davis, USA
Urocortins Promote beta Cell Survival and can Prevent Streptozotocin-Induced Hyperglycaemia

Thursday, March 29 | 2:30PM - 4:30PM
Workshop 2: Survival and Functional Maintenance of the beta
Cell
Room: Steinbeck Forum

Speaker 9 of 9
Hye Seung Jung, Seoul National University Hospital, South Korea
Suppression of Perk Improved Insulin Secretion and Hyperglycemia in beta Cell-Specific Atg7 Knockout Mice

Thursday, March 29 | 4:30PM - 5:00PM
Coffee Available
Room: De Anza Foyer


Thursday, March 29 | 5:00PM - 7:00PM
Maturation and Maintenance of Beta Cell Function
Room: Steinbeck Forum

Speaker 1 of 5
* Chris Wright, Vanderbilt University Medical Center, USA

Thursday, March 29 | 5:00PM - 7:00PM
Maturation and Maintenance of Beta Cell Function
Room: Steinbeck Forum

Speaker 2 of 5
Lori Sussel, University of Colorado Anschutz Medical Campus, USA
Specification and Maintenance of Beta Cell Fate, Identity and Function

Thursday, March 29 | 5:00PM - 7:00PM
Maturation and Maintenance of Beta Cell Function
Room: Steinbeck Forum

Speaker 3 of 5
Roland W. Stein, Vanderbilt University Medical Center, USA
The Effect of Oxidative Stress on Islet beta-Cell-Enriched Transcription Factors

Thursday, March 29 | 5:00PM - 7:00PM
Maturation and Maintenance of Beta Cell Function
Room: Steinbeck Forum

Speaker 4 of 5
Susan Bonner-Weir, Joslin Diabetes Center, USA
Physiological Factors Influence beta Cell Maturation during Early Postnatal Period

Thursday, March 29 | 5:00PM - 7:00PM
Maturation and Maintenance of Beta Cell Function
Room: Steinbeck Forum

Speaker 5 of 5
Barak Blum, University of Wisconsin, USA
Short Talk: Functional Maturation of beta-Cells is Marked by Expression of Urocortin 3

Thursday, March 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: De Anza 1-3


Thursday, March 29 | 8:00PM - 11:00PM
Entertainment
Room: De Anza 1-3


Thursday, March 29 | 8:00PM - 11:00PM
Cash Bar
Room: De Anza 1-3


Friday, March 30 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.