Web Desc
Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics
Organizer(s): Paul W. Noble, Shelia M. Violette and Scott L. Friedman
Date: March 30 - April 04, 2012
Location: Big Sky Resort, Big Sky, MT, USA
Sponsored by Bayer USA Foundation, Celgene Corporation, GlaxoSmithKline UK, Hoffmann-La Roche, Inc. and Regulus Therapeutics Inc.
Summary of Meeting:
Fibrosis is a pathological process in which diseased tissue is replaced with excess extracellular matrix ultimately leading to organ scarring and failure, a final common pathway in many forms of chronic disease affecting multiple tissues. Currently, there are minimal and inadequate treatment options for fibrotic disease. There is an urgent need to understand the cellular, molecular and genetic basis of fibrosis in humans and develop animal models that replicate and illuminate this pathological process. There is also a need to identify prognostic markers of disease susceptibility, biomarkers of disease progression and improved technologies to monitor the effectiveness of new therapies. The goal of the Keystone Symposia meeting on Fibrosis: Translation of Basic Research to Human Disease and Novel Therapeutics is to bring together researchers and clinicians in academia and industry to provide an integrated perspective of basic disease mechanisms, and to address the more pragmatic challenges associated with executing clinical trials and refining approaches to accelerate the clinical development of anti-fibrotic drugs.
Scholarship Deadline: November 30 2011
Discounted Abstract Deadline: November 30 2011
Abstract Deadline: January 5 2012
Discounted Registration Deadline: January 30 2012
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bayer USA FoundationCelgene CorporationGlaxoSmithKline UKHoffmann-La Roche, Inc.Regulus Therapeutics Inc.
We gratefully acknowledge additional support for this conference from:

Celera
InterMune, Inc.Promedior, Inc.Stromedix, Inc.
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Bristol-Myers Squibb Company

Stromedix, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1R13HL112456-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Friday, March 30 | 3:00PM - 7:30PM
Registration
Room: Lower Atrium


Friday, March 30 | 6:15PM - 7:15PM
Refreshments
Room: Lower Atrium


Friday, March 30 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Jefferson/Madison

Speaker 1 of 2
* Paul W. Noble, Cedars-Sinai Medical Center, USA

Friday, March 30 | 7:15PM - 8:30PM
Welcome and Keynote Address
Room: Jefferson/Madison

Speaker 2 of 2
Eric N. Olson, University of Texas Southwestern Medical Center, USA
MicroRNAs in Tissue Remodeling and Disease

Saturday, March 31 | 7:00AM - 8:00AM
Breakfast
Room: Upper Atrium/Lower Atrium


Saturday, March 31 | 8:00AM - 11:15AM
Epithelial Injury, Tissue Remodeling and Repair
Room: Jefferson/Madison

Speaker 1 of 6
Rachel C. Chambers, University College London, UK
Coagulation Cascade, Tissue Injury and Repair in the Lung

Saturday, March 31 | 8:00AM - 11:15AM
Epithelial Injury, Tissue Remodeling and Repair
Room: Jefferson/Madison

Speaker 2 of 6
Victor J. Thannickal, University of Alabama at Birmingham, USA
Targeting the Myofibroblast in Fibrotic Lung Disease

Saturday, March 31 | 8:00AM - 11:15AM
Epithelial Injury, Tissue Remodeling and Repair
Room: Jefferson/Madison

Speaker 3 of 6
Harold A. Chapman, University of California, San Francisco, USA
Epithelial Responses to Lung Injury: Role of the Extracellular Matrix

Saturday, March 31 | 8:00AM - 11:15AM
Epithelial Injury, Tissue Remodeling and Repair
Room: Jefferson/Madison

Speaker 4 of 6
* Dean Sheppard, University of California, San Francisco, USA
Roles for alphav Integrins on Epithelial Cells and Myofibroblasts in Regulating Tissue Fibrosis


Saturday, March 31 | 8:00AM - 11:15AM
Epithelial Injury, Tissue Remodeling and Repair
Room: Jefferson/Madison

Speaker 5 of 6
Lynn M. Schnapp, University of Wisconsin-Madison, USA
Short Talk: Role of Urokinase Plasminogen Activator Receptor Associated Protein (uPARAP) in Lung Injury and Repair

Saturday, March 31 | 8:00AM - 11:15AM
Epithelial Injury, Tissue Remodeling and Repair
Room: Jefferson/Madison

Speaker 6 of 6
Vladimir V. Kalinichenko, Cincinnati Children's Hospital Medical Center, USA
Short Talk: Foxm1 Transcription Factor Increases Epithelial-to-Mesenchymal Transition and is Required for Radiation-Induced Pulmonary Fibrosis

Saturday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Saturday, March 31 | 11:15AM - 1:00PM
Poster Setup
Room: Gallatin


Saturday, March 31 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Saturday, March 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Gallatin


Saturday, March 31 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Saturday, March 31 | 5:00PM - 7:00PM
Unfolded Protein Response and Endoplasmic Reticulum-Stress-I
nduced Injury

Room: Jefferson/Madison

Speaker 1 of 5
* Gisli Jenkins, University of Nottingham, UK

Saturday, March 31 | 5:00PM - 7:00PM
Unfolded Protein Response and Endoplasmic Reticulum-Stress-I
nduced Injury

Room: Jefferson/Madison

Speaker 2 of 5
David Ron, University of Cambridge, UK
Unfolded Protein Stress in the Endoplasmic Reticulum and the Extracellular Matrix

Saturday, March 31 | 5:00PM - 7:00PM
Unfolded Protein Response and Endoplasmic Reticulum-Stress-I
nduced Injury

Room: Jefferson/Madison

Speaker 3 of 5
Timothy S. Blackwell, Vanderbilt University School of Medicine, USA
Dysfunctional Alveolar Epithelial Cells as a Result of Mutant Surfactant Protein C Expression: A Potential Link to Pathogenesis of IPF

Saturday, March 31 | 5:00PM - 7:00PM
Unfolded Protein Response and Endoplasmic Reticulum-Stress-I
nduced Injury

Room: Jefferson/Madison

Speaker 4 of 5
Gökhan S. Hotamisligil, Harvard School of Public Health, USA
ER Stress, Chronic Inflammation, and Metabolic Disease

Saturday, March 31 | 5:00PM - 7:00PM
Unfolded Protein Response and Endoplasmic Reticulum-Stress-I
nduced Injury

Room: Jefferson/Madison

Speaker 5 of 5
Natalie J. Torok, University of California, Davis, USA
Short Talk: TIMP3/TACE Controls Inflammatory and Fibrogenic Activity in Non Alcoholic Steatohepatitis via NADPH Oxidase-Derived Reactive Oxidative Species

Saturday, March 31 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Upper Atrium/Lower Atrium


Saturday, March 31 | 7:30PM - 10:00PM
Poster Session 1
Room: Gallatin


Sunday, April 01 | 7:00AM - 8:00AM
Breakfast
Room: Upper Atrium/Lower Atrium


Sunday, April 01 | 8:00AM - 11:15AM
Progenitor Cells and Cellular Plasticity in Fibrosis
Room: Jefferson/Madison

Speaker 1 of 6
Raghu Kalluri, University of Texas MD Anderson Cancer Center, USA
Organ Fibrosis: Mechanism and Molecular Connection to Cancer

Sunday, April 01 | 8:00AM - 11:15AM
Progenitor Cells and Cellular Plasticity in Fibrosis
Room: Jefferson/Madison

Speaker 2 of 6
Jeremy S. Duffield, Vertex Pharmaceuticals, USA
Cell Fate Mapping and Pericytes in Kidney Injury and Fibrosis

Sunday, April 01 | 8:00AM - 11:15AM
Progenitor Cells and Cellular Plasticity in Fibrosis
Room: Jefferson/Madison

Speaker 3 of 6
* Anna Mae Diehl, Duke University, USA
Hedgehog, Progenitors and Epithelial Progenitors

Sunday, April 01 | 8:00AM - 11:15AM
Progenitor Cells and Cellular Plasticity in Fibrosis
Room: Jefferson/Madison

Speaker 4 of 6
David A. Brenner, University of California, San Diego, USA
Fibrosis from EMT and Non-Resident Mesenchymal Cells - Fact or Fiction?

Sunday, April 01 | 8:00AM - 11:15AM
Progenitor Cells and Cellular Plasticity in Fibrosis
Room: Jefferson/Madison

Speaker 5 of 6
Jelena Mann, Newcastle University, UK
Short Talk: Protective Adaptation to Liver Fibrosis in a Single Generation by Heritable Epigenetic Modifications

Sunday, April 01 | 8:00AM - 11:15AM
Progenitor Cells and Cellular Plasticity in Fibrosis
Room: Jefferson/Madison

Speaker 6 of 6
Ivan Bertoncello, University of Melbourne, Australia
Short Talk: Regulation of Endogenous Lung Epithelial Stem/Progenitor Cells by Lung Mesenchymal Cells and Cytokines

Sunday, April 01 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Sunday, April 01 | 11:15AM - 1:00PM
Poster Setup
Room: Gallatin


Sunday, April 01 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Sunday, April 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Gallatin


Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 1 of 7
* Shelia M. Violette, Q32 Bio, USA

Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 2 of 7
Steven R. Ledbetter, Genzyme Corporation, USA
Neutralizing TGF-beta: A Promising Approach for the Treatment of Chronic Diseases

Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 3 of 7
Eva van Rooij, Hubrecht Institute, Netherlands
Novel Therapeutics in Cardiovascular Disease and Tissue Remodeling

Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 4 of 7
Mark L. Lupher, Jr., Muregen, LLC, USA
PRM-151, Recombinant Human Pentraxin-2: Preclinical and Clinical Progress

Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 5 of 7
James S. Swaney, Inception Sciences, USA
LPA1 Receptor Antagonism in Fibrotic Disease

Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 6 of 7
Victoria Smith, Gilead Sciences, USA
Targeting Loxl2 in Fibrotic Disease

Sunday, April 01 | 2:00PM - 4:30PM
Workshop 1: Development of Novel Therapeutics in Fibrotic Di
sease
Room: Jefferson/Madison

Speaker 7 of 7
Anne Minnich, Sanofi Phamaceuticals, USA
SAR156597: An Innovative Bi-Specific IL-4/IL-13 Antibody as a Potential Treatment for Idiopathic Pulmonary Fibrosis

Sunday, April 01 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Sunday, April 01 | 5:00PM - 7:00PM
Tissue Remodeling in the Tumor Microenvironment
Room: Jefferson/Madison

Speaker 1 of 4
* Sandra S. McAllister, Brigham & Women's Hospital/Harvard Medical School, USA
The Systemic Environment as a Powerful Determinant of Stromal Desmoplasia and Tumor Malignancy

Sunday, April 01 | 5:00PM - 7:00PM
Tissue Remodeling in the Tumor Microenvironment
Room: Jefferson/Madison

Speaker 2 of 4
Jeffrey W. Pollard, Queen's Medical Research Institute, UK
Role of Macrophages and Tissue Remodeling in the Tumor Microenvironment

Sunday, April 01 | 5:00PM - 7:00PM
Tissue Remodeling in the Tumor Microenvironment
Room: Jefferson/Madison

Speaker 3 of 4
Robert F. Schwabe, Columbia University, USA
Promotion of Hepatocarcinogenesis by Activated Hepatic Stellate Cells

Sunday, April 01 | 5:00PM - 7:00PM
Tissue Remodeling in the Tumor Microenvironment
Room: Jefferson/Madison

Speaker 4 of 4
Janusz Franco-Barraza, Fox Chase Cancer Center, USA
Short Talk: alphavbeta5/alpha5beta1-Integrin Crosstalk is Necessary to Maintain a Tumor-ECM Induced Myofibroblastic Phenotype

Sunday, April 01 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Upper Atrium/Lower Atrium


Sunday, April 01 | 7:30PM - 10:00PM
Poster Session 2
Room: Gallatin


Monday, April 02 | 7:00AM - 8:00AM
Breakfast
Room: Upper Atrium/Lower Atrium


Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 1 of 7
* Scott L. Friedman, Icahn School of Medicine at Mount Sinai, USA

Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 2 of 7
Thomas A. Wynn, Pfizer, USA
Regulation of Fibrosis by IL-13, IL-17, and Macrophages

Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 3 of 7
Paul W. Noble, Cedars-Sinai Medical Center, USA
Innate Immune Regulation of Lung Fibrosis

Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 4 of 7
Andrew P. Fontenot, University of Colorado Denver, USA
Immune Mechanisms of Lung Fibrosis in Granulomatous Inflammation

Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 5 of 7
Tamiko R. Katsumoto, Stanford University, USA
Short Talk: The Receptor-Type Protein Tyrosine Phosphatase CD148 Positively Regulates Pro-Fibrotic Signaling Pathways in Bleomycin-Induced Lung Fibrosis

Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 6 of 7
William C. Parks, University of Washington, USA
MMPs Shape Fibrosis via Controlling Macrophage Activation

Monday, April 02 | 8:00AM - 11:15AM
Innate and Adaptive Mechanisms of Fibrosis
Room: Jefferson/Madison

Speaker 7 of 7
Christian Stockmann, University of Zurich, Switzerland
Short Talk: Aberrant Remodeling of the Lymphatic Vasculature during Pulmonary Fibrosis – The Lymphatic Drainage Capacity as a Determinating Factor of Fibroproliferative Changes in the Lung

Monday, April 02 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Monday, April 02 | 11:15AM - 1:00PM
Poster Setup
Room: Gallatin


Monday, April 02 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Monday, April 02 | 1:00PM - 10:00PM
Poster Viewing
Room: Gallatin


Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 1 of 7
* Martin R. J. Kolb, McMaster University, Canada

Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 2 of 7
Pär Gerwins, Uppsala University, Sweden
An in vivo Neovascularization Assay for Screening Regulators of Angiogenesis and Assessing their Effects on Pre-Existing Vessels

Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 3 of 7
Emily Hamburg, Case Western Reserve University, USA
Stabilized beta-Catenin Activity in Dermal Fibroblasts Leads to Skin Fibrosis

Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 4 of 7
Lukasz Stawski, Boston University, USA
Angiotensin II Induces Skin Fibrosis: A Novel Mouse Model of Dermal Fibrosis

Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 5 of 7
Tomoko Hayashida, Northwestern University, USA
Distinct and Sequential Roles for PI3Ks and TGF-beta Mediating Glomerular Sclerosis in Mouse Adriamycin Nephropathy

Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 6 of 7
Matthew Frieman, University of Maryland, USA
Contribution of Alternatively Activated Macrophages to a Pro-Fibrotic Response during SARS Coronavirus Infection

Monday, April 02 | 2:00PM - 4:30PM
Workshop 2: Modeling Injury and Fibrosis
Room: Jefferson/Madison

Speaker 7 of 7
Reinout Stoop, TNO, Netherlands
Combination of Deuterated Water Labeling and Transcriptomics Analysis Identifies Processes Contributing to Collagen Deposition during Pulmonary Fibrosis

Monday, April 02 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Monday, April 02 | 5:00PM - 7:00PM
Fibroblasts and Myofibroblasts
Room: Jefferson/Madison

Speaker 1 of 4
Sem H. Phan, University of Michigan Medical School, USA
Regulation of Myofibroblast Differentiation

Monday, April 02 | 5:00PM - 7:00PM
Fibroblasts and Myofibroblasts
Room: Jefferson/Madison

Speaker 2 of 4
* Rebecca G. Wells, University of Pennsylvania, USA
Myofibroblasts in Liver Fibrosis

Monday, April 02 | 5:00PM - 7:00PM
Fibroblasts and Myofibroblasts
Room: Jefferson/Madison

Speaker 3 of 4
John Varga, Feinberg School of Medicine, USA
Impaired PPAR-gamma Signaling in Scleroderma: Therapeutic Target

Monday, April 02 | 5:00PM - 7:00PM
Fibroblasts and Myofibroblasts
Room: Jefferson/Madison

Speaker 4 of 4
Claire Dugast-Darzacq, Institut de Biologie de l' École Normale Supérieure (IBENS), France
Short Talk: Identification of Key Transcription Factors in the Regulation of Fibroblast to Myofibroblast Differentiation in an ex vivo Model of Chronic Wound

Monday, April 02 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Upper Atrium/Lower Atrium


Monday, April 02 | 7:30PM - 10:00PM
Poster Session 3
Room: Gallatin


Tuesday, April 03 | 7:00AM - 8:00AM
Breakfast
Room: Upper Atrium/Lower Atrium


Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 1 of 7
* Michael Gilman, Arrakis Therapeutics, USA

Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 2 of 7
Naftali Kaminski, Yale University School of Medicine, USA
RNA, microRNA and Protein Biomarkers in Interstitial Lung Disease

Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 3 of 7
Shelia M. Violette, Q32 Bio, USA
Developing a Biomarker Strategy to Support the Clinical Development of STX-100, an alphavbeta6 Antibody, in Fibrotic Disease

Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 4 of 7
Robert Lafyatis, University of Pittsburgh Medical Center, USA
Biomarkers as Predictors of Disease in Scleroderma

Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 5 of 7
Gabe Kwong, Georgia Institute of Technology, USA
Nanoparticle-Based Urinary Biomarkers in Liver Disease

Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 6 of 7
Kenn Holmbeck, NIDCR, National Institutes of Health, USA
Short Talk: Connective Tissue Homeostasis is Dependent on Membrane-Type Matrix Metalloproteinase (MT-MMP) Activity for Resolution of Fibrosis

Tuesday, April 03 | 8:00AM - 11:15AM
Biomarkers in Fibrotic Disease: Facilitating Clinical Develo
pment

Room: Jefferson/Madison

Speaker 7 of 7
Peter Caravan, Harvard Medical School, Massachusetts General Hospital, USA
Short Talk: Collagen-Targeted Molecular MR Imaging of Liver Fibrosis

Tuesday, April 03 | 9:20AM - 9:40AM
Coffee Break
Room: Lower Atrium


Tuesday, April 03 | 11:15AM - 11:15AM
On Own for Lunch and Recreation


Tuesday, April 03 | 4:30PM - 5:00PM
Coffee Available
Room: Lower Atrium


Tuesday, April 03 | 5:00PM - 7:00PM
What's New in the Field: Clinical Developments in Fibrosis
Room: Jefferson/Madison

Speaker 1 of 5
* Richard P. Marshall, GlaxoSmithKline, UK

Tuesday, April 03 | 5:00PM - 7:00PM
What's New in the Field: Clinical Developments in Fibrosis
Room: Jefferson/Madison

Speaker 2 of 5
Williamson Z. Bradford, Intermune, Inc., USA
IPF Drug Development: Trials, Tribulations, and New Opportunities

Tuesday, April 03 | 5:00PM - 7:00PM
What's New in the Field: Clinical Developments in Fibrosis
Room: Jefferson/Madison

Speaker 3 of 5
Scott L. Friedman, Icahn School of Medicine at Mount Sinai, USA
Prospects for Antifibrotics in Liver Disease

Tuesday, April 03 | 5:00PM - 7:00PM
What's New in the Field: Clinical Developments in Fibrosis
Room: Jefferson/Madison

Speaker 4 of 5
Timothy W. Schacker, University of Minnesota, USA
Short Talk: Antifibrotic Therapy in SIV Infection Preserves CD4 T Cell Populations and Improves Immune Reconstitution With Antiretroviral Therapy

Tuesday, April 03 | 5:00PM - 7:00PM
What's New in the Field: Clinical Developments in Fibrosis
Room: Jefferson/Madison

Speaker 5 of 5
Christopher L. Leptak, Food and Drug Administration, USA
Biomarker Utility in Drug Development and Clinical Trials: An FDA Regulatory Perspective

Tuesday, April 03 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Upper Atrium/Lower Atrium


Tuesday, April 03 | 8:00PM - 11:00PM
Entertainment
Room: Madison/Gallatin


Tuesday, April 03 | 8:00PM - 11:00PM
Cash Bar
Room: Madison/Gallatin


Wednesday, April 04 | 10:25AM - 10:25AM
Departure


*Session Chair.