Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Mechanisms and Consequences of Invertebrate-Microbe Interactions (2014A7)

Web Desc
Fungal Pathogens: From Basic Biology to Drug Discovery joint with Drug Discovery for Protozoan Parasites Organizer(s): Joseph Heitman, John Taylor and Leah E. Cowen Date: January 15 - 20, 2012 Location: Santa Fe Community Convention Center, Santa Fe, NM, USA Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation. For important information on the coronavirus, please click here Summary of Meeting: The aim of this meeting is to bring together the academic, medical and pharmaceutical communities focused on fungal microbial pathogens of humans and other animals to illustrate common themes, and therapeutic, diagnostic and preventive opportunities. We seek to bridge both basic and physician-scientists working on the pathogenic microbe (via genetics, cell biology, genomics) and the host (immunology, including both innate and adaptive immunity). With respect to therapeutics, the emphasis is on developed as well as novel therapeutics, including both drugs and vaccines. A key aspect is to bridge the communities working on the diversity of fungi that infect humans and those working on the chytrid outbreak causing amphibian decline and extinctions. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Drug Discovery for Protozoan Parasites, which will share the keynote address and two plenary sessions with this meeting. Global Health Travel Award Deadline: August 16 2011 Scholarship Deadline: September 19 2011 Discounted Abstract Deadline: September 19 2011 Abstract Deadline: October 19 2011 Discounted Registration Deadline: November 15 2011 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: Department of Molecular Genetics and Microbiology, Duke University Medical Center We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Anacor Pharmaceuticals, Inc. Scynexis, Inc. Joseph Heitman Adriana Secatto Sarti We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI098158-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Fungal Pathogens: From Basic Biology to Drug Discovery

joint with Drug Discovery for Protozoan Parasites

Organizer(s): Joseph Heitman, John Taylor and Leah E. Cowen

Date: January 15 - 20, 2012
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation.

For important information on the coronavirus, please click here

Summary of Meeting:

The aim of this meeting is to bring together the academic, medical and pharmaceutical communities focused on fungal microbial pathogens of humans and other animals to illustrate common themes, and therapeutic, diagnostic and preventive opportunities. We seek to bridge both basic and physician-scientists working on the pathogenic microbe (via genetics, cell biology, genomics) and the host (immunology, including both innate and adaptive immunity). With respect to therapeutics, the emphasis is on developed as well as novel therapeutics, including both drugs and vaccines. A key aspect is to bridge the communities working on the diversity of fungi that infect humans and those working on the chytrid outbreak causing amphibian decline and extinctions. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Drug Discovery for Protozoan Parasites, which will share the keynote address and two plenary sessions with this meeting.

Global Health Travel Award Deadline: August 16 2011

Scholarship Deadline: September 19 2011

Discounted Abstract Deadline: September 19 2011

Abstract Deadline: October 19 2011

Discounted Registration Deadline: November 15 2011

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

Department of Molecular Genetics and Microbiology, Duke University Medical Center

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Anacor Pharmaceuticals, Inc.

Scynexis, Inc.

Joseph Heitman

Adriana Secatto Sarti

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI098158-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, January 15 \| 3:00PM - 7:30PM Registration Room: Sweeney Ballroom Foyer
Sunday, January 15 \| 6:15PM - 7:15PM Refreshments Room: Sweeney Ballroom F
Sunday, January 15 \| 7:15PM - 7:30PM Welcoming Remarks (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 6 Norman C. Waters, United States Military Academy, USA
Sunday, January 15 \| 7:15PM - 7:30PM Welcoming Remarks (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 6 Frederick S. Buckner, University of Washington, USA
Sunday, January 15 \| 7:15PM - 7:30PM Welcoming Remarks (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 6 * Vicky M. Avery, Griffith University, Australia
Sunday, January 15 \| 7:15PM - 7:30PM Welcoming Remarks (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 6 Joseph Heitman, Duke University, USA
Sunday, January 15 \| 7:15PM - 7:30PM Welcoming Remarks (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 6 John Taylor, University of California, Berkeley, USA
Sunday, January 15 \| 7:15PM - 7:30PM Welcoming Remarks (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 6 Leah E. Cowen, University of Toronto, Canada
Sunday, January 15 \| 7:30PM - 9:00PM Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 4 * Norman C. Waters, United States Military Academy, USA
Sunday, January 15 \| 7:30PM - 9:00PM Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 4 Dennis E. Kyle, University of Georgia, USA Managing Risk and Exploiting Success in Antiprotozoan Drug Development
Sunday, January 15 \| 7:30PM - 9:00PM Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 4 * John Taylor, University of California, Berkeley, USA
Sunday, January 15 \| 7:30PM - 9:00PM Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 4 Arturo Casadevall, Albert Einstein College of Medicine, USA On Fungal Virulence
Monday, January 16 \| 7:00AM - 8:00AM Breakfast Room: Sweeney Ballroom F
Monday, January 16 \| 7:30AM - 8:00AM Poster Setup Room: Sweeney Ballroom F
Monday, January 16 \| 8:00AM - 5:00PM Poster Viewing Room: Sweeney Ballroom F
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 1 of 7 * Arturo Casadevall, Albert Einstein College of Medicine, USA
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 2 of 7 Robin C. May, University of Birmingham, UK Fungus-Phagocyte Interactions: Understanding Fungal Virulence in vitro, in vivo and in Fish-o
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 3 of 7 Kirsten Nielsen, University of Minnesota, USA Short Talk: Cryptococcal Titan Cell Formation Affects Interactions with the Host and Subsequent Pathogenesis
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 4 of 7 William E. Goldman, University of North Carolina at Chapel Hill, USA Intracellular Survival Strategies of Histoplasma capsulatum
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 5 of 7 Nuri Rodriguez Del Val, University of Puerto Rico, USA An RNAi and Yeast Two-Hybrid Study of Calcium/Calmodulin Kinase1 and its Relationship to Thermotolerance and HSP90 in Sporothrix schencki
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 6 of 7 Melanie T. Cushion, University of Cincinnati College of Medicine, USA Stealth and Opportunism: Strategies for Survival of Pneumocystis within the Mammalian Lung
Monday, January 16 \| 8:00AM - 11:15AM Mechanisms of Virulence Room: Sweeney Ballroom C-E Speaker 7 of 7 Robert A. Cramer, Montana State University, USA Short Talk: Defining the Hypoxia Response of Aspergillus fumigatus: Implications for Fungal Pathogenesis and Antifungal Drugs
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 1 of 7 * Pradipsinh K. Rathod, University of Washington, USA
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 2 of 7 Philip J. Rosenthal, University of California, San Francisco, USA Selection for Decreased Sensitivity to Artemisinin Partner Drugs
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 3 of 7 Qin Cheng, Australian Army Malaria Institute, Australia Artemisinin Induced Dormancy and Resistance in Plasmodium falciparum in vitro
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 4 of 7 David A. Fidock, Columbia University Medical Center, USA Balancing Drug Resistance and Fitness via Compensatory Mutations in the Plasmodium falciparum Chloroquine Resistance Transporter
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 5 of 7 Rentala Madhubala, Jawaharlal Nehru University, India A Comparative Proteomics Approach to Understand the Mode of Action and Mechanism of Drug Resistance in Leishmania donovani
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 6 of 7 Leann M. Tilley, University of Melbourne, Australia Short Talk: Potent Artemisinin Activity against Plasmodium falciparum Requires Hemoglobin Uptake and Digestion
Monday, January 16 \| 8:00AM - 11:15AM Drug Resistance I This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 7 of 7 Dylan R. Pillai, University of Calgary, Canada Short Talk: Reversing Antimalarial Resistance by Targeting Plasmodium falciparum Heat Shock Protein (PfHsp)90
Monday, January 16 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom F
Monday, January 16 \| 11:15AM - 12:00PM Lunch Room: Sweeney Ballroom F
Monday, January 16 \| 12:00PM - 2:30PM Poster Session 1 Room: Sweeney Ballroom F
Monday, January 16 \| 2:30PM - 4:30PM Workshop 1: NIH Funding Opportunities (Joint) Room: Sweeney Ballroom C-E
Monday, January 16 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom F
Monday, January 16 \| 5:00PM - 7:00PM Host Responses to Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 1 of 5 * Annika E. Scheynius, Karolinska Institutet, Sweden
Monday, January 16 \| 5:00PM - 7:00PM Host Responses to Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 2 of 5 Aimee K. Zaas, Duke University Medical Center, USA Host Gene Expression Response to Fungal Infection
Monday, January 16 \| 5:00PM - 7:00PM Host Responses to Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 3 of 5 Gordon D. Brown, University of Aberdeen, UK Immunity to Fungal Infections, Innate and Adaptive?
Monday, January 16 \| 5:00PM - 7:00PM Host Responses to Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 4 of 5 Paul L. Fidel, Jr., Louisiana State University Health Science Center, USA Host Defense Against Mucosal Candida Infections: Opportunities for New Immunotherapeutics
Monday, January 16 \| 5:00PM - 7:00PM Host Responses to Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 5 of 5 Kimberly Gerik, Washington University School of Medicine, USA Short Talk: Chitinases – Pathogen Signaling and Host Response to C. neoformans
Monday, January 16 \| 5:00PM - 7:15PM Drug Target Identification, Validation and Screening This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 1 of 6 * Don L. Gardiner, Queensland Institute of Medical Research, Australia
Monday, January 16 \| 5:00PM - 7:15PM Drug Target Identification, Validation and Screening This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 2 of 6 Geoffrey Ian McFadden, University of Melbourne, Australia Life Cycle Studies to Identify When and Where Malaria Parasites are Vulnerable
Monday, January 16 \| 5:00PM - 7:15PM Drug Target Identification, Validation and Screening This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 3 of 6 Emily Derbyshire, Duke University, USA Efforts to Target and Disrupt Liver Stage Development of the Malarial Parasite
Monday, January 16 \| 5:00PM - 7:15PM Drug Target Identification, Validation and Screening This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 4 of 6 William A. Petri, Jr., University of Virginia, USA Transmembrane Kinases of Entamoeba histolytica
Monday, January 16 \| 5:00PM - 7:15PM Drug Target Identification, Validation and Screening This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 5 of 6 Norman C. Waters, United States Military Academy, USA Short Talk: Targeting the Cell Cycle Machinery of Plasmodium falciparum
Monday, January 16 \| 5:00PM - 7:15PM Drug Target Identification, Validation and Screening This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 6 of 6 Audrey R. Odom, Washington University School of Medicine, USA Short Talk: Targeting Methylerythritol Cytidyltransferase (IspD) for Antimalarial Drug Discovery
Monday, January 16 \| 7:00PM - 7:00PM On Own for Dinner
Tuesday, January 17 \| 7:00AM - 8:00AM Breakfast Room: Sweeney Ballroom F
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 1 of 9 * Meg Phillips, University of Texas Southwestern Medical Center, USA
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 2 of 9 * Audrey R. Odom, Washington University School of Medicine, USA
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 3 of 9 Leah E. Cowen, University of Toronto, Canada New Therapeutic Strategies for Fungal Disease Based on Combinatorial Control
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 4 of 9 Dickon Alley, Anacor Pharmaceuticals, Inc., USA Boron-based Agents for Fungal and Protozoan Infections
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 5 of 9 Xuewen Pan, Baylor College of Medicine, USA Short Talk: Novel Functional Genomics Approaches for Drug Target Identification and Validation
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 6 of 9 Frederick S. Buckner, University of Washington, USA Sterol 14-Demethylase Inhibitors for Chagas Disease
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 7 of 9 Andrew P. Waters, University of Glasgow, UK Commitment to sexual development – towards an understanding of a molecular mechanism.
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 8 of 9 Dominic Hoepfner, Novartis Institutes for BioMedical Research, Switzerland Short Talk: Cladosporin, a Natural Product with Antifungal and Antimalarial Activity Targets lysyl-tRNA Synthetase
Tuesday, January 17 \| 8:00AM - 11:30AM Drug Discovery for Eukaryotic Pathogens and Parasites (Joint ) Room: Sweeney Ballroom A-E Speaker 9 of 9 Doron C. Greenbaum, University of Pennsylvania, USA Short Talk: Small Molecule Mimics of Antimicrobial Peptides as Antimalarials
Tuesday, January 17 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom F
Tuesday, January 17 \| 11:30AM - 1:00PM Poster Setup Room: Sweeney Ballroom F
Tuesday, January 17 \| 11:30AM - 11:30AM On Own for Lunch and Recreation
Tuesday, January 17 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney Ballroom F
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 11 Lakshmi Goyal, Cell Press, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 11 Arturo Casadevall, Albert Einstein College of Medicine, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 11 Aaron P. Mitchell, Carnegie Mellon University, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 11 Meg Phillips, University of Texas Southwestern Medical Center, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 11 Kevin J. Saliba, Australian National University, Australia
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 11 Joseph Heitman, Duke University, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 11 Alexander D. Johnson, University of California, San Francisco, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 8 of 11 Tamara L. Doering, Washington University Medical School, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 9 of 11 Judith G. Berman, University of Minnesota, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 10 of 11 Tom Edlind, Drexel University College of Medicine, USA
Tuesday, January 17 \| 2:30PM - 4:30PM Workshop 2: Publishing (Joint) Room: Sweeney Ballroom A-E Speaker 11 of 11 Leah E. Cowen, University of Toronto, Canada
Tuesday, January 17 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom F
Tuesday, January 17 \| 5:00PM - 7:00PM Evolution and Comparative Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 1 of 5 * Charles W. Saunders, USA
Tuesday, January 17 \| 5:00PM - 7:00PM Evolution and Comparative Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 2 of 5 Jim Kronstad, University of British Columbia, Canada Pathogenic Basidiomycetes: Metabolic Adaptation and Virulence Factor Expression
Tuesday, January 17 \| 5:00PM - 7:00PM Evolution and Comparative Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 3 of 5 Emily Troemel, University of California, San Diego, USA Non-lytic Escape of Microsporidia from C. elegans Intestinal Cells
Tuesday, January 17 \| 5:00PM - 7:00PM Evolution and Comparative Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 4 of 5 Axel A. Brakhage, Friedrich Schiller University, Germany Dermatophyte Genomics and Secondary Metabolites Involved in Fungal Pathogenicity
Tuesday, January 17 \| 5:00PM - 7:00PM Evolution and Comparative Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 5 of 5 Annika E. Scheynius, Karolinska Institutet, Sweden Short Talk: The Basidiomycete Malassezia Species Complex – A Genomic Platform to Elucidate Host-Fungal Interactions Involved in Common Skin Disorders
Tuesday, January 17 \| 5:00PM - 7:15PM Hit to Lead Identification This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 1 of 6 * Paul G. Wyatt, University of Dundee, UK
Tuesday, January 17 \| 5:00PM - 7:15PM Hit to Lead Identification This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 2 of 6 Michael Riscoe, Oregon Health & Science University, USA Revisiting Historical Leads for Clues to the Design of Future Antimalarial Drugs.
Tuesday, January 17 \| 5:00PM - 7:15PM Hit to Lead Identification This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 3 of 6 Bakela Nare, SCYNEXIS, Inc., USA Development of Oxaborole Compounds for Human African Trypanosomiasis
Tuesday, January 17 \| 5:00PM - 7:15PM Hit to Lead Identification This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 4 of 6 Richard Glynne, Genomics Institute of the Novartis Research Foundation, USA High-Throughput Whole-Cell Screening against Trypanosomatids
Tuesday, January 17 \| 5:00PM - 7:15PM Hit to Lead Identification This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 5 of 6 Richard W. Heidebrecht, Jr., Broad Institute, USA Short Talk: Identification of a Novel Lead for the Treatment of Malaria via Diversity Oriented Synthesis
Tuesday, January 17 \| 5:00PM - 7:15PM Hit to Lead Identification This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 6 of 6 Mark E. Drew, Ohio State University College of Medicine, USA Short Talk: Potent Antiprotozoal Activity of a Novel Semi-Synthetic Berberine Derivative
Tuesday, January 17 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney Ballroom F
Tuesday, January 17 \| 7:30PM - 10:00PM Poster Session 2 Room: Sweeney Ballroom F
Wednesday, January 18 \| 7:00AM - 8:00AM Breakfast Room: Sweeney Ballroom F
Wednesday, January 18 \| 8:00AM - 11:15AM Cell Circuitry and Adaptive Responses Room: Sweeney Ballroom C-E Speaker 1 of 6 Alexander D. Johnson, University of California, San Francisco, USA Evolution of Gene Regulation in Fungi
Wednesday, January 18 \| 8:00AM - 11:15AM Cell Circuitry and Adaptive Responses Room: Sweeney Ballroom C-E Speaker 2 of 6 Aaron P. Mitchell, Carnegie Mellon University, USA Portrait of Candida albicans Adherence Regulators
Wednesday, January 18 \| 8:00AM - 11:15AM Cell Circuitry and Adaptive Responses Room: Sweeney Ballroom C-E Speaker 3 of 6 Hiten D. Madhani, University of California, San Francisco, USA Using a Gene Deletion Collection to Understand how Cryptococcus neoformans Causes Disease and Responds to Chemicals
Wednesday, January 18 \| 8:00AM - 11:15AM Cell Circuitry and Adaptive Responses Room: Sweeney Ballroom C-E Speaker 4 of 6 Maurizio Del Poeta, Medical University of South Carolina, USA Short Talk: Identification of New Compounds Targeting the Fungal Sphingolipid Pathway
Wednesday, January 18 \| 8:00AM - 11:15AM Cell Circuitry and Adaptive Responses Room: Sweeney Ballroom C-E Speaker 5 of 6 * Tamara L. Doering, Washington University Medical School, USA Short Talk: Toward an Integrated Model of Capsule Regulation in Cryptococcus neoformans
Wednesday, January 18 \| 8:00AM - 11:15AM Cell Circuitry and Adaptive Responses Room: Sweeney Ballroom C-E Speaker 6 of 6 Anita Sil, University of California, San Francisco, USA Regulation of Histoplasma Cell Shape and Virulence by Temperature
Wednesday, January 18 \| 8:00AM - 11:00AM Pre-Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 1 of 6 * Thierry T. Diagana, Novartis Institute for Tropical Diseases, USA
Wednesday, January 18 \| 8:00AM - 11:00AM Pre-Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 2 of 6 Susan A. Charman, Monash University, Australia Genesis of OZ439: From Preclinical Studies to Clinical Trials
Wednesday, January 18 \| 8:00AM - 11:00AM Pre-Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 3 of 6 Julio A. Urbina, Venezuelan Institute for Science Research, USA Ergosterol Biosynthesis Inhibitors for the Specific Treatment of Chagas Disease: From Basic Science to Clinical Trials
Wednesday, January 18 \| 8:00AM - 11:00AM Pre-Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 4 of 6 Michael Zhuo Wang, University of Kansas, USA Evaluation of Novel Anti-Trypanosomal Benzofuran Derivatives: Pharmacokinetics, Toxicity, and Efficacy
Wednesday, January 18 \| 8:00AM - 11:00AM Pre-Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 5 of 6 Rosa M. Andrade, University of California, San Diego, USA Short Talk: A Reprofiled Drug, Auranofin, Targets the Thioredoxin Reductase of Entamoeba histolytica and is Cysticidal
Wednesday, January 18 \| 8:00AM - 11:00AM Pre-Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 6 of 6 Maria Jose Lafuente, GlaxoSmithKline, Spain Short Talk: Open Source to Drug Discovery for Malaria: Sharing TCAMS
Wednesday, January 18 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom F
Wednesday, January 18 \| 11:15AM - 12:15PM Workshop 3: Fungal Genome Databases Room: Sweeney Ballroom C-E Speaker 1 of 1 * Jason E. Stajich, University of California, Riverside, USA
Wednesday, January 18 \| 11:15AM - 1:00PM Poster Setup Room: Sweeney Ballroom F
Wednesday, January 18 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Wednesday, January 18 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney Ballroom F
Wednesday, January 18 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom F
Wednesday, January 18 \| 5:00PM - 7:00PM Population Genetics and Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 1 of 5 * Fred S. Dietrich, Duke University, USA
Wednesday, January 18 \| 5:00PM - 7:00PM Population Genetics and Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 2 of 5 Matthew C. Fisher, Imperial College, London, UK Why Fungi Cause Species Extinctions: Evolutionary Insights from Population Genetics and Genomics
Wednesday, January 18 \| 5:00PM - 7:00PM Population Genetics and Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 3 of 5 Timothy Y. James, University of Michigan, USA Pathogen Recombination during the Amphibian Chytridiomycosis Pandemic - Why Change What's Working?
Wednesday, January 18 \| 5:00PM - 7:00PM Population Genetics and Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 4 of 5 Geraldine Butler, University College Dublin, Ireland Beyond the Candida albicans Paradigm: Evolution of the Hypoxic Response in Fungal Species
Wednesday, January 18 \| 5:00PM - 7:00PM Population Genetics and Genomics of Fungal Pathogens Room: Sweeney Ballroom C-E Speaker 5 of 5 Guilhem Janbon, Institut Pasteur, France Short Talk: Regulation of Gene Expression by Intron in Cryptococcus Neoformans
Wednesday, January 18 \| 5:00PM - 7:00PM Lead Optimization This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 1 of 5 * Susan A. Charman, Monash University, Australia
Wednesday, January 18 \| 5:00PM - 7:00PM Lead Optimization This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 2 of 5 Meg Phillips, University of Texas Southwestern Medical Center, USA Targeting Malaria Dihydroorotate Dehydrogenase
Wednesday, January 18 \| 5:00PM - 7:00PM Lead Optimization This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 3 of 5 Geoffrey S. Dow, United States Army Medical & Material Development Activity, USA Lead Optimization and Development of Next Generation Quinoline Methanols for Malaria Treatment and Prevention
Wednesday, January 18 \| 5:00PM - 7:00PM Lead Optimization This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 4 of 5 Paul G. Wyatt, University of Dundee, UK Validation of N-Myristoyltransferase as a Drug Target
Wednesday, January 18 \| 5:00PM - 7:00PM Lead Optimization This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 5 of 5 Michael P. Pollastri, Northeastern University, USA Short Talk: Optimization of a Human Aurora Kinase Inhibitor Chemotype for Selective Anti-Trypanosomal Activity
Wednesday, January 18 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney Ballroom F
Wednesday, January 18 \| 7:30PM - 10:00PM Poster Session 3 Room: Sweeney Ballroom F
Thursday, January 19 \| 7:00AM - 8:00AM Breakfast Room: Sweeney Ballroom F
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 8 * Michael T. Ferdig, University of Notre Dame, USA
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 8 * Mitchell Mutz, Roche Venture Fund, USA
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 8 Judith G. Berman, University of Minnesota, USA Aneuploidy and Drug Resistance in Pathogenic Fungi
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 8 Pradipsinh K. Rathod, University of Washington, USA Accelerated Acquisition of Drug Resistance in Malaria: The Problem and a Possible New Solution
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 8 Thomas E. Wellems, NIAID, National Institutes of Health, USA Drug-Resistant Malaria: Determinants of Treatment Outcome and Prospects for Control
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 8 Geoffrey H. Siwo, University of Notre Dame, USA Short Talk: Rewired Gene Networks Predict Differential Chemosensitivities of Multi-Drug Resistant Malaria Parasites
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 8 Damian Krysan, University of Rochester, USA Short Talk: Protein Kinase Inhibitors as Antifungal Molecules: HTS Identification, Evaluation and Mechanism of Action
Thursday, January 19 \| 8:00AM - 11:15AM Drug Resistance II/Antifungal Strategies and Resistance Mech anisms (Joint) Room: Sweeney Ballroom A-E Speaker 8 of 8 Bruce Klein, University of Wisconsin-Madison, USA Fungi Subvert Vaccine T-Cell Priming at the Respiratory Mucosa by Inducing MMP2 and Retarding CCL7-Mediated Influx of Inflammatory Monocytes
Thursday, January 19 \| 9:00AM - 9:20AM Coffee Break Room: Sweeney Ballroom F
Thursday, January 19 \| 11:15AM - 12:15PM Workshop 4: Career Development Room: Sweeney Ballroom A-E
Thursday, January 19 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Thursday, January 19 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom F
Thursday, January 19 \| 5:00PM - 7:00PM Sex, Cell Identity and Virulence Room: Sweeney Ballroom C-E Speaker 1 of 5 * Haoping Liu, University of California, Irvine, USA
Thursday, January 19 \| 5:00PM - 7:00PM Sex, Cell Identity and Virulence Room: Sweeney Ballroom C-E Speaker 2 of 5 Richard Bennett, Brown University, USA Phenotypic Switching and Sexual Reproduction in Candida Species
Thursday, January 19 \| 5:00PM - 7:00PM Sex, Cell Identity and Virulence Room: Sweeney Ballroom C-E Speaker 3 of 5 Paul Dyer, University of Nottingham, UK Cryptic Sex in Aspergillus
Thursday, January 19 \| 5:00PM - 7:00PM Sex, Cell Identity and Virulence Room: Sweeney Ballroom C-E Speaker 4 of 5 Christina M. Hull, University of Wisconsin, Madison, USA When Sex is Hazardous to Your Health: Pathogenesis of Cryptococcus Spores
Thursday, January 19 \| 5:00PM - 7:00PM Sex, Cell Identity and Virulence Room: Sweeney Ballroom C-E Speaker 5 of 5 Xiaorong Lin, Texas A&M University, USA Short Talk: A Link in Disguise: Sex-Independent Fungal Morphogenesis and Virulence
Thursday, January 19 \| 5:00PM - 7:00PM Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 1 of 5 * Vicky M. Avery, Griffith University, Australia
Thursday, January 19 \| 5:00PM - 7:00PM Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 2 of 5 J. Kevin Baird, Eijkman Institute for Molecular Biology, Indonesia Severe Morbidity and Mortality in Vivax Malaria and Chemotherapeutics Challenges in Coping with that Threat
Thursday, January 19 \| 5:00PM - 7:00PM Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 3 of 5 Anjan Debnath, University of California, San Francisco, USA Short Talk: Drug Discovery for Naegleria
Thursday, January 19 \| 5:00PM - 7:00PM Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 4 of 5 Alison Webster, GlaxoSmithKline, UK Tafenoquine: Lessons Learned
Thursday, January 19 \| 5:00PM - 7:00PM Clinical Development This session is from Protozoan Parasites Room: Sweeney Ballroom A-B Speaker 5 of 5 Thierry T. Diagana, Novartis Institute for Tropical Diseases, USA Discovery and Development of Novel Antimalarial Drugs for the Treatment of P. falciparum and P. vivax Malaria
Thursday, January 19 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney Ballroom F
Thursday, January 19 \| 8:00PM - 11:00PM Entertainment Room: Sweeney Ballroom F
Thursday, January 19 \| 8:00PM - 11:00PM Cash Bar Room: Sweeney Ballroom F
Friday, January 20 \| 10:23AM - 10:23AM Departure *Session Chair †Invited, not yet responded.