Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
	Diabetes: Glucose Control and Beyond (2020J5)
Diabetes (2017J3)
Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies (2016T2)
Diabetes and Metabolic Dysfunction (2015J6)
Challenges and Opportunities in Diabetes Research and Treatment (2014J1)
Diabetes - New Insights into Mechanism of Disease and its Treatment (2013J6)

Web Desc
Pathogenesis of Diabetes: Emerging Insights into Molecular Mechanisms joint with Genetic and Molecular Basis of Obesity and Body Weight Regulation Organizer(s): Alan D. Attie, Christopher B. Newgard and Philipp E. Scherer Date: January 29 - February 03, 2012 Location: Santa Fe Community Convention Center, Santa Fe, NM, USA Sponsored by Pfizer Inc. and MedImmune Summary of Meeting: This meeting will focus on genetic, epigenetic and biochemical mechanisms underlying the pathogenesis of diabetes. New methods, particularly proteomics and the ability to interrogate protein modifications (phosphorylation, acetylation, methylation) on a large scale, are providing a new window into the pathological processes in type 2 diabetes. Other emerging themes are the CNS control of metabolism, the role of the microbiome in regulating metabolism, and transdifferentiation of cells in the endocrine pancreas in the adaptive response to obesity and insulin resistance. The strength of this meeting lies in the interdisciplinary nature of these topics. Pathogenesis of Diabetes: Emerging Insights into Molecular Mechanisms is held jointly with a the Keystone Symposia meeting on Genetic and Molecular Basis of Obesity and Body Weight Regulation, an obvious match with any conference devoted to type 2 diabetes; for example, adipose tissue function is dramatically changed in obesity, and adipocytes and adipose tissue immune cells produce proteins that modulate insulin signaling. Scholarship Deadline: September 29 2011 Discounted Abstract Deadline: September 29 2011 Abstract Deadline: November 1 2011 Discounted Registration Deadline: November 29 2011 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: Journal of Lipid Research We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Bristol-Myers Squibb Company Eli Lilly and Company Metabolic Solutions Development Company, LLC. Marc Prentki We gratefully acknowledge the generous grant for this conference provided by: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Grant No. 5R13DK084688-03 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Pathogenesis of Diabetes: Emerging Insights into Molecular Mechanisms

joint with Genetic and Molecular Basis of Obesity and Body Weight Regulation

Organizer(s): Alan D. Attie, Christopher B. Newgard and Philipp E. Scherer

Date: January 29 - February 03, 2012
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA

Program


Sunday, January 29 \| 3:00PM - 7:30PM Registration Room: Sweeney Ballroom Foyer
Sunday, January 29 \| 6:15PM - 7:15PM Refreshments Room: Sweeney F, Main Level Breakout Rooms
Sunday, January 29 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 4 * Alan D. Attie, University of Wisconsin-Madison, USA
Sunday, January 29 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 4 * Evan D. Rosen, Harvard University, USA
Sunday, January 29 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 4 Aldons J. Lusis, University of California, Los Angeles, USA Systems Genetics Analysis of Complex Interactions in Cardiometabolic Traits
Sunday, January 29 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 4 Daniel J. Rader, University of Pennsylvania, USA From GWAS to Gene Function: Genetics and Physiology of Lipid and Lipoprotein Metabolism
Monday, January 30 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakout Rooms
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 7 * Philipp E. Scherer, University of Texas Southwestern Medical Center, USA
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 7 C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA Novel Aspects of Insulin Action and their Role in Development of Insulin Resistance
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 7 Jeffrey M. Friedman, Rockefeller University, USA Leptin: From Production to Pathways
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 7 Gökhan S. Hotamisligil, Harvard School of Public Health, USA Inflammation and ER Stress in Obesity and Diabetes
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 7 Bruce M. Spiegelman, Harvard Medical School, USA Irisin, a Novel Myokine that Browns Adipose Tissues and Ameliorates Metabolic Disease
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 7 Alexander Rauch, University of Southern Denmark, Denmark Short Talk: Glucocorticoids Dampen Insulin Sensitivity via the Dimerisation of the Glucocorticoid Receptor in Peripheral Organs
Monday, January 30 \| 8:00AM - 11:15AM Inflammation, ER Stress, Insulin Resistance (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 7 Susan J. Gray, University of Massachusetts Medical School, USA Short Talk: KLF15: A Critical Link between Insulin Resistance and ER Stress
Monday, January 30 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney F, Main Level Breakout Rooms
Monday, January 30 \| 11:15AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakout Rooms
Monday, January 30 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Monday, January 30 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakout Rooms
Monday, January 30 \| 2:30PM - 4:30PM Workshop 1: Health Disparities (Joint). Supported by Novart is Institutes for BioMedical Research Room: Sweeney Ballroom A-B Speaker 1 of 3 * William C. Hsu, Harvard Medical School, Joslin Diabetes Center, USA Biology and Clinical Implications of Diabetes in Asian Americans
Monday, January 30 \| 2:30PM - 4:30PM Workshop 1: Health Disparities (Joint). Supported by Novart is Institutes for BioMedical Research Room: Sweeney Ballroom A-B Speaker 2 of 3 Charles N. Rotimi, NHGRI, National Institutes of Health, USA Genetics, Environment and Health Disparities in Diabetes among African Americans
Monday, January 30 \| 2:30PM - 4:30PM Workshop 1: Health Disparities (Joint). Supported by Novart is Institutes for BioMedical Research Room: Sweeney Ballroom A-B Speaker 3 of 3 Struan F. A. Grant, Children’s Hospital of Philadelphia Research Institute, USA Genome Wide Studies of Pediatric Metabolic Traits in Multi-Ethnic Settings
Monday, January 30 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney F, Main Level Breakout Rooms
Monday, January 30 \| 5:00PM - 7:00PM Islet Biology Room: Sweeney Ballroom C-E Speaker 1 of 5 * Christopher B. Newgard, Duke University Medical Center, USA
Monday, January 30 \| 5:00PM - 7:00PM Islet Biology Room: Sweeney Ballroom C-E Speaker 2 of 5 Debbie C. Thurmond, Indiana University School of Medicine, USA Molecular Regulators of Insulin Exocytosis
Monday, January 30 \| 5:00PM - 7:00PM Islet Biology Room: Sweeney Ballroom C-E Speaker 3 of 5 Anil Bhushan, University of California, San Francisco, USA Epigenetics Control of Islet Formation and Regeneration
Monday, January 30 \| 5:00PM - 7:00PM Islet Biology Room: Sweeney Ballroom C-E Speaker 4 of 5 Rohit N. Kulkarni, Joslin Diabetes Center, Harvard Medical School, USA Growth Factor Signaling in the Regulation of Islet Function and Proliferation
Monday, January 30 \| 5:00PM - 7:00PM Islet Biology Room: Sweeney Ballroom C-E Speaker 5 of 5 Wook Kim, Ajou University, South Korea Short Talk: Cannabinoids Induce Pancreatic Beta-Cell Death by Directly Inhibiting Insulin Receptor Activation
Monday, January 30 \| 5:00PM - 7:00PM Lipid Droplets and Lipid Handling This session is from Obesity Room: Sweeney Ballroom A-B Speaker 1 of 5 * Deborah M. Muoio, Duke University Medical Center, USA
Monday, January 30 \| 5:00PM - 7:00PM Lipid Droplets and Lipid Handling This session is from Obesity Room: Sweeney Ballroom A-B Speaker 2 of 5 Dawn L. Brasaemle, Rutgers University, USA Control of Lipolysis by Perilipins
Monday, January 30 \| 5:00PM - 7:00PM Lipid Droplets and Lipid Handling This session is from Obesity Room: Sweeney Ballroom A-B Speaker 3 of 5 Rudolf Zechner, University of Graz, Austria Mouse Models of Altered Lipolysis
Monday, January 30 \| 5:00PM - 7:00PM Lipid Droplets and Lipid Handling This session is from Obesity Room: Sweeney Ballroom A-B Speaker 4 of 5 Tobias C. Walther, Harvard School of Public Health, USA Mechanisms of Lipid Droplet Growth
Monday, January 30 \| 5:00PM - 7:00PM Lipid Droplets and Lipid Handling This session is from Obesity Room: Sweeney Ballroom A-B Speaker 5 of 5 Sheila Collins, Vanderbilt University Medical Center, USA Short Talk: Cardiac Natriuretic Peptides Act via p38 MAPK to Induce the Brown Fat Thermogenic Program in Mouse and Human Adipocytes
Monday, January 30 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakout Rooms
Monday, January 30 \| 7:30PM - 10:00PM Poster Session 1 Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 7 * Aldons J. Lusis, University of California, Los Angeles, USA
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 7 Alan D. Attie, University of Wisconsin-Madison, USA Genes for Type 2 Diabetes from Genetics and Genomics
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 7 Joseph H. Nadeau, Maine Medical Center Research Institute, USA Epistasis, Fractal Genetics and Systems Properties of Metabolic Traits
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 7 Sadaf Farooqi, University of Cambridge, UK Genetics of Human Obesity-Monogenic Disorders
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 7 Joel N. Hirschhorn, Children's Hospital, Boston, USA Genome-Wide Association Studies and Genetics of Human Obesity
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 7 Nuno Rocha, Institute of Metabolic Science, University of Cambridge, UK Short Talk: ARL15: A Novel Player in Metabolic Disease
Tuesday, January 31 \| 8:00AM - 11:15AM Genetics (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 7 Carl S. Thummel, University of Utah School of Medicine, USA Short Talk: MPC1 Plays an Essential Role in Pyruvate Metabolism in Yeast, Drosophila, and Human Disease
Tuesday, January 31 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 11:15AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, January 31 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Regulatory Pathways in Metabolism Room: Sweeney Ballroom C-E Speaker 1 of 5 * Steven A. Kliewer, University of Texas Southwestern Medical Center, USA
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Regulatory Pathways in Metabolism Room: Sweeney Ballroom C-E Speaker 2 of 5 Rana K. Gupta, University of Texas Southwestern Medical Center, USA Developmental Origin and Molecular Control of Adipose Progenitors
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Regulatory Pathways in Metabolism Room: Sweeney Ballroom C-E Speaker 3 of 5 Matthias Hebrok, University of California, San Francisco, USA Hypoxia and Beta-Cell Dysfunction
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Regulatory Pathways in Metabolism Room: Sweeney Ballroom C-E Speaker 4 of 5 Ajay Chawla, Merck Research Labs, USA Innate Immune Cells Regulate Adipose Tissue Metabolism
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Regulatory Pathways in Metabolism Room: Sweeney Ballroom C-E Speaker 5 of 5 Ron F. Morrison, University of North Carolina, Greensboro, USA Short Talk: Novel Mechanism of Golgi-Mediated TNFalpha-Induced Inflammatory Gene Expression in Adipocytes
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Aspects of Adipocyte Biology This session is from Obesity Room: Sweeney Ballroom A-B Speaker 1 of 5 * Sheila Collins, Vanderbilt University Medical Center, USA
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Aspects of Adipocyte Biology This session is from Obesity Room: Sweeney Ballroom A-B Speaker 2 of 5 Juleen R. Zierath, Karolinska Institutet, Sweden Genetic and Environmental Modulators of Insulin Sensitivity
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Aspects of Adipocyte Biology This session is from Obesity Room: Sweeney Ballroom A-B Speaker 3 of 5 Barbara Cannon, Stockholm University, Sweden Brown and Brite Adipose Tissues: Characteristics and Significance
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Aspects of Adipocyte Biology This session is from Obesity Room: Sweeney Ballroom A-B Speaker 4 of 5 Bart Staels, Institut Pasteur de Lille, Université Lille, France Macrophage Polarization in Obesity and Atherosclerosis
Tuesday, January 31 \| 5:00PM - 7:00PM Novel Aspects of Adipocyte Biology This session is from Obesity Room: Sweeney Ballroom A-B Speaker 5 of 5 J. Andrew Pospisilik, Van Andel Institute, USA Short Talk: Rapid Rewiring of Adipocyte Metabolism by a Novel Hedgehog-Ampk Axis
Tuesday, January 31 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakout Rooms
Tuesday, January 31 \| 7:30PM - 10:00PM Poster Session 2 Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 7 * C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 7 Christopher B. Newgard, Duke University Medical Center, USA Metabolomics and Metabolic Disease
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 7 Christopher K. Glass, University of California, San Diego, USA Genomics and Lipidomics of Macrophage Activation
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 7 Markus Stoffel, ETH Zürich, Switzerland Exploring the beta Cell Surface Proteome and Secretome
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 7 Elaine Holmes, Imperial College London, UK Systems Biology of the Gut Microbiome and Mammalian Metabolism
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 7 Cole Trapnell, University of Washington, USA Short Talk: Long Noncoding RNAs Regulate Adipogenesis
Wednesday, February 01 \| 8:00AM - 11:15AM Integration of -Omics Data in Diabetes Research (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 7 Ryan Berry, Yale University, USA Short Talk: Analysis of Gene Networks in White Adipose Tissue Development Reveals a Role for ETS2 in Adipogenesis
Wednesday, February 01 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 11:15AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Wednesday, February 01 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 1 of 10 * David E. Moller, Eli Lilly and Company, USA
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 2 of 10 Richard D. DiMarchi, Indiana University and Novo Nordisk, USA Keynote Address: Multi-Functional Peptides Targeting Metabolic Disease
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 3 of 10 Simeon Taylor, University of Maryland School of Medicine, USA SGLT2 Inhibition - Target to Clinical Proof-of-Concept - Lessons Learned
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 4 of 10 Dominic P. Behan, Sentia Medical Sciences, Inc., USA GPR 119 Agonists for the Treatment of Diabetes
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 5 of 10 Thomas Kjeldsen, Novo Nordisk, Denmark Engineering of Next Generation Insulin Analogues
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 6 of 10 David E. Kelley, Merck & Co., Inc., USA Glucokinase Activators - Target Validation to In-Depth Clinical Testing
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 7 of 10 Paul Emmerson, Eli Lilly and Company, USA Short talk: Metabolic Actions through Modulation of FGF Receptor 1c Signaling
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 8 of 10 Yang Li, Amgen Inc., USA Short Talk: Novel Approaches to Targeting the FGF21 Pathway
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 9 of 10 Patrick R. Griffin, The Scripps Research Institute, USA Short Talk: PPARG Non-Agonists
Wednesday, February 01 \| 1:00PM - 4:30PM Workshop 2: New Therapeutic Targets and Challenges (Joint) Room: Sweeney Ballroom A-E Speaker 10 of 10 Rolf F. Kletzien, Metabolic Solutions Development, Inc., USA Short Talk: Insulin Sensitization Through a Mitochondrial Metabolic Switch that Modulates Wnt Signaling
Wednesday, February 01 \| 2:40PM - 3:00PM Coffee Break Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 5:00PM - 7:00PM New Concepts in Glucose Metabolism Room: Sweeney Ballroom C-E Speaker 1 of 5 * Morris F. White, Boston Children's Hospital, Harvard Medical School, USA
Wednesday, February 01 \| 5:00PM - 7:00PM New Concepts in Glucose Metabolism Room: Sweeney Ballroom C-E Speaker 2 of 5 Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA Regulation of Metabolic Pathways to Support Cell Proliferation
Wednesday, February 01 \| 5:00PM - 7:00PM New Concepts in Glucose Metabolism Room: Sweeney Ballroom C-E Speaker 3 of 5 Donald A. McClain, University of Utah School of Medicine, USA O-Glycosylation and Diabetes
Wednesday, February 01 \| 5:00PM - 7:00PM New Concepts in Glucose Metabolism Room: Sweeney Ballroom C-E Speaker 4 of 5 Domenico Accili, Columbia University, USA Identification of New Drug Targets to Treat Insulin Resistance in the CNS, Liver, and Pancreatic Beta-Cells
Wednesday, February 01 \| 5:00PM - 7:00PM New Concepts in Glucose Metabolism Room: Sweeney Ballroom C-E Speaker 5 of 5 Nigel Beaton, Institute of Food, Nutrition and Health, Switzerland Short Talk: Tusc5 Controls Insulin Mediated Glucose Uptake by Facilitating Glut4 Membrane Fusion
Wednesday, February 01 \| 5:00PM - 7:00PM Epigenetics This session is from Obesity Room: Sweeney Ballroom A-B Speaker 1 of 5 * Juleen R. Zierath, Karolinska Institutet, Sweden
Wednesday, February 01 \| 5:00PM - 7:00PM Epigenetics This session is from Obesity Room: Sweeney Ballroom A-B Speaker 2 of 5 Evan D. Rosen, Harvard University, USA Epigenomics of Metabolic Dysfunction
Wednesday, February 01 \| 5:00PM - 7:00PM Epigenetics This session is from Obesity Room: Sweeney Ballroom A-B Speaker 3 of 5 Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA Cistromes and the Tissue-Specific Physiology of HDAC3
Wednesday, February 01 \| 5:00PM - 7:00PM Epigenetics This session is from Obesity Room: Sweeney Ballroom A-B Speaker 4 of 5 Susanne Mandrup, University of Southern Denmark, Denmark Hotspots Orchestrating Adipocyte Differentiation
Wednesday, February 01 \| 5:00PM - 7:00PM Epigenetics This session is from Obesity Room: Sweeney Ballroom A-B Speaker 5 of 5 Hironori Waki, University of Tokyo, Japan Short Talk: Global Mapping of Cell-Type-Specific Open Chromatin by FAIRE-seq Reveals the Regulatory Role of the NFI Family in Adipocyte Differentiation
Wednesday, February 01 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakout Rooms
Wednesday, February 01 \| 7:30PM - 10:00PM Poster Session 3 Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 7:30AM - 8:00AM Poster Setup Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 1 of 7 * Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 2 of 7 Eleftheria Maratos-Flier, Beth Israel Deaconess Medical Center, USA FGF21: A New Player in Metabolic Homeostasis and Disease
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 3 of 7 Steven A. Kliewer, University of Texas Southwestern Medical Center, USA FGF21: From Feast to Famine
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 4 of 7 Philipp E. Scherer, University of Texas Southwestern Medical Center, USA Mechanistic Insights into Adipose Tissue and Hepatic Insulin Sensitivity
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 5 of 7 Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA Novel Mechanisms by which Adipocytes Regulate Systemic Insulin Sensitivity
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 6 of 7 Lei Cao, Ohio State University, USA Short Talk: White to Brown Fat Phenotypic Switch Induced by Genetic and Environmental Activation of a Hypothalamic-Sympathoneural-Adipocyte Axis
Thursday, February 02 \| 8:00AM - 11:15AM Hormones that Modulate Metabolism and Insulin Sensitivity (J oint) Room: Sweeney Ballroom A-E Speaker 7 of 7 Stephanie E. Simonds, Monash University, Australia Short Talk: Hypertension in Obesity, is Leptin the Culprit?
Thursday, February 02 \| 8:00AM - 7:00PM Poster Viewing Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 9:00AM - 9:20AM Coffee Break Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 11:15AM - 12:00PM Lunch Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 12:00PM - 2:30PM Poster Session 4 Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 1 of 8 * Rohit N. Kulkarni, Joslin Diabetes Center, Harvard Medical School, USA
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 2 of 8 Ahmed Kablan, National Institutes of Health, USA Gs-alpha Deficiency in POMC Neurons Leads to Hyperglycemia with Reduced Serum Insulin Levels and Impaired Counterregulation to Hypoglycemia
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 3 of 8 Craig Hammond, Eli Lilly and Company, USA A Novel Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor Increases Plasma GLP-1 Levels and Reduces Body Weight Gain
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 4 of 8 Shirly Pinto, Kallyope, USA Mechanisms Underlying Diacylglycerol Acyltransferase 1 Inhibition – Potential insight into Modulation of Gut Peptides Release
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 5 of 8 Sharon M. Blättler, Genomics Institute of the Novartis Research Foundation, USA Yin Yang 1 Deficiency in Skeletal Muscle Protects Against Rapamycin-induced Diabetic-like Symptoms through Activation of Insulin/IGF Signaling
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 6 of 8 Zheng Sun, Baylor College of Medicine, USA Dissociation of Fatty Liver and Insulin Resistance in Mice Lacking Hepatic HDAC3
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 7 of 8 Lale Ozcan, Columbia University, USA Inhibition of Hepatic Calcium/Calmodulin-Dependent Protein Kinase II Protects against Obesity-Induced Insulin Resistance and Fatty Liver Formation
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments Room: Sweeney Ballroom C-E Speaker 8 of 8 Jose M. Irimia-Dominguez, Indiana University, USA Inability to Synthesize Glycogen in Liver Leads to Enhanced Lipid Synthesis and Liver Insulin Resistance
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 1 of 8 * Mary-Elizabeth Patti, Joslin Diabetes Center, USA
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 2 of 8 Marin Gantner, Lowy Medical Research Institute, USA Identification of a Novel Energy Expenditure Regulatory Pathway in Brown Adipose Tissue
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 3 of 8 Wen Kong, Joslin Diabetes Center, USA STARS Regulates AMPK Phosphorylation and Oxidative Capacity
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 4 of 8 Susana Rodriguez, Johns Hopkins University School of Medicine, USA Targeted Chemical-Genetic Metabolic Regulation in vivo
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 5 of 8 Michael Lutter, University of Texas Southwestern Medical Center, USA Melanocortin 4 Receptor Signaling in Habit/Procedural Memory Learning
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 6 of 8 Kristy L. Townsend, University of Maine, USA Deletion of Bone Morphogenetic Protein Receptor 1a (BMPR1a) in POMC Neurons Results in Hyperphagia and Increased Sympathetic Outflow to Brown and White Adipose Tissues
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 7 of 8 Florian W. Kiefer, Brigham and Women's Hospital, Harvard Medical School, USA Retinaldehyde Dehydrogenase 1 Determines a Thermogenic Program in White Adipose Tissue
Thursday, February 02 \| 2:30PM - 4:30PM Workshop 3: Late Breaking Developments This session is from Obesity Room: Sweeney Ballroom A-B Speaker 8 of 8 James E. Minchin, Duke University, USA Longitudinal in vivo Imaging in Zebrafish Reveals Oscillatory Hyperplastic and Hypertrophic Adipose Tissue Growth is Regulated by a Pre-Patterned Vascular Network
Thursday, February 02 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 5:00PM - 7:00PM Insulin Action Room: Sweeney Ballroom C-E Speaker 1 of 5 * Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Thursday, February 02 \| 5:00PM - 7:00PM Insulin Action Room: Sweeney Ballroom C-E Speaker 2 of 5 Michael P. Czech, University of Massachusetts Medical School, USA New Insights into the Insulin Signaling Pathway
Thursday, February 02 \| 5:00PM - 7:00PM Insulin Action Room: Sweeney Ballroom C-E Speaker 3 of 5 Morris F. White, Boston Children's Hospital, Harvard Medical School, USA The Regulation of Insulin Signaling by Serine/Threonine Phosphorylation of Irs1
Thursday, February 02 \| 5:00PM - 7:00PM Insulin Action Room: Sweeney Ballroom C-E Speaker 4 of 5 Deborah M. Muoio, Duke University Medical Center, USA Journal of Lipid Research Lectureship: Mechanisms of Fatty Acid-Induced Insulin Resistance
Thursday, February 02 \| 5:00PM - 7:00PM Insulin Action Room: Sweeney Ballroom C-E Speaker 5 of 5 Min Lu, Merck Research Laboroatory, USA Short Talk: Neuronal SIRT1 Deficiency Causes Central and Whole-Body Insulin Sensitivity
Thursday, February 02 \| 5:00PM - 7:00PM CNS Control of Metabolism This session is from Obesity Room: Sweeney Ballroom A-B Speaker 1 of 4 * Martin G. Myers, Jr., University of Michigan, USA Leptin Signaling in the Brain
Thursday, February 02 \| 5:00PM - 7:00PM CNS Control of Metabolism This session is from Obesity Room: Sweeney Ballroom A-B Speaker 2 of 4 Allison W. Xu, University of California, San Francisco, USA Adaptive Regulation of Energy Balance by Central Melanocortinergic Neurons
Thursday, February 02 \| 5:00PM - 7:00PM CNS Control of Metabolism This session is from Obesity Room: Sweeney Ballroom A-B Speaker 3 of 4 Jens C. Brüning, Max Planck Institute for Metabolism Research, Germany CNS Control of Metabolism
Thursday, February 02 \| 5:00PM - 7:00PM CNS Control of Metabolism This session is from Obesity Room: Sweeney Ballroom A-B Speaker 4 of 4 Yong Xu, Baylor College of Medicine, USA Short Talk: CNS Circuitry Mediating Estrogenic Effects on Energy Homeostasis
Thursday, February 02 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 8:00PM - 11:00PM Entertainment Room: Sweeney F, Main Level Breakout Rooms
Thursday, February 02 \| 8:00PM - 11:00PM Cash Bar Room: Sweeney F, Main Level Breakout Rooms
Friday, February 03 \| 10:25AM - 10:25AM Departure *Session Chair.