Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Why So Many Ways to Die? Apoptosis, Necroptosis, Pyroptosis and Beyond (2020T3)
Cell Death, Inflammation and Adaptation to Tissue Stress (2018A6)
Cell Death and Inflammation (2017K2)
Cell Death Signaling in Cancer and the Immune System (2015S2)
The Chemistry and Biology of Cell Death (2014Q6)

Web Desc
Cell Death Pathways: Beyond Apoptosis joint with Mitochondrial Dynamics and Function Organizer(s): Serge Przedborski and Richard J. Youle Date: March 19 - 24, 2012 Location: Fairmont Banff Springs, Banff, AB, Canada Sponsored by Abbott Laboratories, Astellas Pharma Inc. and Genentech, Inc. Summary of Meeting: Mounting evidence indicates that cell death in diseases results from complex interactions between molecular mechanisms taking place within the degenerating cells (cell-autonomous) and outside the degenerating cells (non-cell autonomous). At the cross roads of these diverse signaling pathways are found the mitochondria which, through proper mitochondrial dynamics and regulated mitochondrial elimination by autophagy (i.e., mitophagy), play a crucial role in maintaining the well-being of the cells. This meeting will focus on the general mechanisms of cell death including the Bcl-2 family and caspase proteases, the role of mitochondrial dynamics and mitophagy, the usefulness of bioinformatics to unravel death-pathways, the contribution of non-cell autonomous mechanisms to cell death and the therapeutic strategies to protect against cell death. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Mitochondrial Dynamics and Function, which will share a keynote address and two plenary sessions with this meeting. Scholarship Deadline: November 17 2011 Discounted Abstract Deadline: November 17 2011 Abstract Deadline: December 21 2011 Discounted Registration Deadline: January 19 2012 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Neurological Disorders and Stroke (NINDS) Grant No. 1R13NS077708-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Cell Death Pathways: Beyond Apoptosis

joint with Mitochondrial Dynamics and Function

Organizer(s): Serge Przedborski and Richard J. Youle

Date: March 19 - 24, 2012
Location: Fairmont Banff Springs, Banff, AB, Canada

Sponsored by Abbott Laboratories, Astellas Pharma Inc. and Genentech, Inc.

Summary of Meeting:

Mounting evidence indicates that cell death in diseases results from complex interactions between molecular mechanisms taking place within the degenerating cells (cell-autonomous) and outside the degenerating cells (non-cell autonomous). At the cross roads of these diverse signaling pathways are found the mitochondria which, through proper mitochondrial dynamics and regulated mitochondrial elimination by autophagy (i.e., mitophagy), play a crucial role in maintaining the well-being of the cells. This meeting will focus on the general mechanisms of cell death including the Bcl-2 family and caspase proteases, the role of mitochondrial dynamics and mitophagy, the usefulness of bioinformatics to unravel death-pathways, the contribution of non-cell autonomous mechanisms to cell death and the therapeutic strategies to protect against cell death. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Mitochondrial Dynamics and Function, which will share a keynote address and two plenary sessions with this meeting.

Scholarship Deadline: November 17 2011

Discounted Abstract Deadline: November 17 2011

Abstract Deadline: December 21 2011

Discounted Registration Deadline: January 19 2012

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Neurological Disorders and Stroke (NINDS)
Grant No. 1R13NS077708-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Monday, March 19 \| 3:00PM - 7:30PM Registration Room: Van Horne Foyer
Monday, March 19 \| 6:15PM - 7:15PM Refreshments Room: Van Horne Foyer
Monday, March 19 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Van Horne A-B Speaker 1 of 4 * Luca Scorrano, University of Padova, Italy
Monday, March 19 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Van Horne A-B Speaker 2 of 4 Heidi M. McBride, McGill University, Canada Mitochondrial Dynamics and Quality Control
Monday, March 19 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Van Horne A-B Speaker 3 of 4 Junying Yuan, Harvard Medical School, USA Programmed Cell Death: From Apoptosis to Necroptosis
Monday, March 19 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Van Horne A-B Speaker 4 of 4 * Serge Przedborski, Columbia University, USA
Tuesday, March 20 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 1 of 7 * Richard J. Youle, NINDS, National Institutes of Health, USA
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 2 of 7 Kim McCall, Boston University, USA Mitochondrial Dynamics and Cell Death in Drosophila Oogenesis
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 3 of 7 Luca Scorrano, University of Padova, Italy Integrating Mitochondrial Morphology and Ultrastructure in the Control of Apoptosis: Lessons from Cellular and Mouse Models
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 4 of 7 Seamus J. Martin, Trinity College Dublin, Ireland Mitochondrial Quality Control and the Bcl-2 Family
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 5 of 7 Joseph T. Opferman, St. Jude Children's Research Hospital, USA Anti-Apoptotic MCL-1 Localizes to the Mitochondrial Matrix and Regulates Mitochondrial Function
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 6 of 7 Michelangelo Campanella, RVC and UCL Consortium for Mitochondrial Research, UK Short Talk: The F1FO-ATPsynthase Inhibitor IF1 Controls Apoptosis by Regulating Mitochondrial Dynamics
Tuesday, March 20 \| 8:00AM - 11:15AM Mitochondrial Dynamics in Cell Death (Joint) Room: Van Horne A-B Speaker 7 of 7 Nuno Raimundo, University Medical Center Goettingen, Germany Short Talk: Mitochondrial Stress Triggers E2F1 Apoptotic Signaling to Cause Deafness – Insights into Tissue-Specific Mechanisms
Tuesday, March 20 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Tuesday, March 20 \| 11:15AM - 1:00PM Poster Setup Room: Mezzanine 2
Tuesday, March 20 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, March 20 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 1 of 7 * Carol M. Troy, Columbia University Medical Center, USA
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 2 of 7 Patrick A. Lewis, University of Reading, UK The ROC Domain of DAPK1 as a Controller of DAPK1 Function and Cell Death
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 3 of 7 Meera Nanjundan, University of South Florida, USA Role of SnoN/SkiL in Modulating Cell Death Pathways in the Pathogenesis of Ovarian Cancer
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 4 of 7 Sho Morioka, North Carolina State University, USA TAK1 Regulates Mitochondrial Integrity, Which Is Important for Preventing TNF-Induced Endothelial Cell Death and Vascular Development
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 5 of 7 Yuxing Zhao, St. Vincent's Institute, Australia Apoptotic and Non-Apoptotic Pathways Lead to Pancreatic beta Cell Destruction in Type 1 Diabetes
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 6 of 7 Susan E. Brockerhoff, University of Washington, USA Mechanisms of Photoreceptor Degeneration
Tuesday, March 20 \| 2:30PM - 4:30PM Workshop 1: Non-Apoptotic Death Pathways: Mechanisms and Con sequences Room: Van Horne C Speaker 7 of 7 Jason Karch, Cincinnati Children's Hospital Medical Center, USA Bax and Bak Are Required For Mitochondrial Permeability Transition Pore-Dependent Programmed Cellular Necrosis
Tuesday, March 20 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Tuesday, March 20 \| 5:00PM - 7:15PM Atypical Caspase-Dependent Cell Death Mechanisms Room: Van Horne C Speaker 1 of 6 * Junying Yuan, Harvard Medical School, USA
Tuesday, March 20 \| 5:00PM - 7:15PM Atypical Caspase-Dependent Cell Death Mechanisms Room: Van Horne C Speaker 2 of 6 Andreas Villunger, Medical University Innsbruck, Austria The PIDDosome in Cell Death and Cell Cycle Regulation
Tuesday, March 20 \| 5:00PM - 7:15PM Atypical Caspase-Dependent Cell Death Mechanisms Room: Van Horne C Speaker 3 of 6 David Wallach, Weizmann Institute of Science, Israel The ‘Apoptotic’ Caspases as Regulators of Inflammation: New Lessons about Caspase-8 Function
Tuesday, March 20 \| 5:00PM - 7:15PM Atypical Caspase-Dependent Cell Death Mechanisms Room: Van Horne C Speaker 4 of 6 Douglas R. Green, St. Jude Children's Research Hospital, USA Cutting Both Ways: Why FADD, FLIP, and Caspase-8 are Required for Embryonic Development
Tuesday, March 20 \| 5:00PM - 7:15PM Atypical Caspase-Dependent Cell Death Mechanisms Room: Van Horne C Speaker 5 of 6 Kenta Moriwaki, University of Massachusetts Medical School, USA Short Talk: Molecular Mechanism and Pathophysiological Roles of RIP3-Dependent Necrosis
Tuesday, March 20 \| 5:00PM - 7:15PM Atypical Caspase-Dependent Cell Death Mechanisms Room: Van Horne C Speaker 6 of 6 Liming Sun, Institute of Biochemistry and Cell Biology, SIBS, CAS, China Short Talk: MLKL Mediates Necrosis Signaling Downstream of RIP3
Tuesday, March 20 \| 5:00PM - 7:00PM Building the Organelle: The Import of Protein and Lipids This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 5 * Mike Ryan, Monash University, Australia
Tuesday, March 20 \| 5:00PM - 7:00PM Building the Organelle: The Import of Protein and Lipids This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 5 Jodi Nunnari, University of California, Davis, USA The Behavior of Mitochondria
Tuesday, March 20 \| 5:00PM - 7:00PM Building the Organelle: The Import of Protein and Lipids This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 5 Hiromi Sesaki, Johns Hopkins University School of Medicine, USA Mitochondrial Division Prevents Neurodegeneration
Tuesday, March 20 \| 5:00PM - 7:00PM Building the Organelle: The Import of Protein and Lipids This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 5 Thomas Langer, CECAD Research Center, Germany Proteolytic Control of Mitochondrial Membrane Dynamics
Tuesday, March 20 \| 5:00PM - 7:00PM Building the Organelle: The Import of Protein and Lipids This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 5 Nils-Goran Larsson, Karolinska Institutet, Sweden Short Talk: Posttranscriptional Regulation of mtDNA Expression in Animals
Tuesday, March 20 \| 7:15PM - 8:00PM Social Hour with Lite Bites Room: Mezzanine 2
Tuesday, March 20 \| 7:30PM - 10:00PM Poster Session 1 Room: Mezzanine 2
Wednesday, March 21 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 1 of 7 * Maya Saleh, McGill University, Canada
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 2 of 7 Andrea Califano, Columbia University, USA Interrogating Gene Regulatory Networks to Discover Oncogene and Non-Oncogene Addictions in Cancer
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 3 of 7 Al L. Burlingame, University of California, San Francisco, USA Cell Death Pathways: Beyond Apoptosis
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 4 of 7 Paul J. Muchowski, University of California, San Francisco, USA Using Yeast to Identify Pathways that Modify Neurodegeneration
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 5 of 7 Cole M. Haynes, University of Massachusetts Medical School, USA Retrograde Signaling a Mitochondrial Unfolded Protein Response
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 6 of 7 Burcin Ikiz, Trustees of Columbia University in the City of New York, USA Short Talk: Unraveling the Molecular Mechanism Underlying ALS-Linked Astrocyte Toxicity to Motor Neurons
Wednesday, March 21 \| 8:00AM - 11:15AM Bioinformatics at the Service of the Death-omes Room: Van Horne C Speaker 7 of 7 Lars Brichta, Rockefeller University, USA Short Talk: Comparative Translational Profiling of Dopaminergic Neurons in Mouse Models for Parkinson’s Disease
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 7 * Nils-Goran Larsson, Karolinska Institutet, Sweden
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 7 Paolo Bernardi, University of Padova Medical School, Italy Pathophysiology of the Mitochondrial Permeability Transition
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 7 Rosario Rizzuto, University of Padua, Italy Identification of the Mitochondrial Calcium Uniporter
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 7 David C. Chan, California Institute of Technology, USA Analysis of Mitochondrial Dynamics in Mouse Tissues
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 7 Anu Suomalainen Wartiovaara, University of Helsinki, Finland Global and Tissue-Specific Consequences of Mitochondrial Dysfunction
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 6 of 7 Pénélope Andreux, Amazentis, Switzerland Short Talk: A Multi-Level Screen in Mammals and the Worm C. elegans for the Identification of Compounds Improving Mitochondrial Function
Wednesday, March 21 \| 8:00AM - 11:15AM Making the Organelle to Work: From Genetics to (Dys)function This session is from Mitochondria Room: Van Horne A-B Speaker 7 of 7 Vanessa A. Morais, Katholieke Universiteit Leuven & VIB, Belgium Short Talk: Parkinson’s Disease: PINK1 Regulates Complex I Activity
Wednesday, March 21 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Wednesday, March 21 \| 11:15AM - 1:00PM Poster Setup Room: Mezzanine 2
Wednesday, March 21 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Wednesday, March 21 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 9 * David C. Chan, California Institute of Technology, USA
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 9 Maria Bohnert, Weizmann Institute of Science, Israel MINOS, a Novel Mitochondrial Inner Membrane Organizing System
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 9 Uma Sankar, University of Louisville, USA Regulation of the Mitochondrial Fission GTPase Drp1 by the Sulfhydryl Oxidase GFER
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 9 Axel Niemann, ETH Zürich, Switzerland GDAP1-Induced Fission Allows Protection during ROS Stress Conditions
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 9 Julio C. B. Ferreira, Institute of Biomedical Sciences, Brazil Disruption of Mitochondria Fusion Contributes to Heart Failure; A Role for betaIIPKC
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 6 of 9 Adam L. Hughes, University of Utah, USA A Yeast PINK1/Parkin-Like Mitophagy Pathway
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 7 of 9 Jonathon L. Burman, University of Washington, USA Selective Vulnerability of Mitochondria in Parkin Mutant Dopaminergic Neurons
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 8 of 9 Lindsay DeVorkin, Deeley Research Centre, Canada A Drosophila Effector Caspase Mediates Mitochondrial Dynamics and Autophagy
Wednesday, March 21 \| 2:30PM - 4:30PM Workshop 1: Extending Mitochondrial Fusion and Fission: Mech anisms and Consequences This session is from Mitochondria Room: Van Horne A-B Speaker 9 of 9 John J. Lemasters, Medical University of South Carolina, USA Different Initiators of Mitochondrial Autophagy in Types 1 and 2 Mitophagy
Wednesday, March 21 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Wednesday, March 21 \| 5:00PM - 7:15PM Bcl-2 Protein Family Room: Van Horne C Speaker 1 of 6 * Rajiv R. Ratan, Burke-Cornell Medical Research Institute, USA
Wednesday, March 21 \| 5:00PM - 7:15PM Bcl-2 Protein Family Room: Van Horne C Speaker 2 of 6 Atan J. Gross, Weizmann Institute of Science, Israel A Novel Mitochondrial Pathway that Regulates Cell Fate and Function
Wednesday, March 21 \| 5:00PM - 7:15PM Bcl-2 Protein Family Room: Van Horne C Speaker 3 of 6 Ruth M. Kluck, Walter and Eliza Hall Institute of Medical Research, Australia How Bak and Bax Permeabilize Mitochondria during Cell Death
Wednesday, March 21 \| 5:00PM - 7:15PM Bcl-2 Protein Family Room: Van Horne C Speaker 4 of 6 Maya Saleh, McGill University, Canada The Pro-Apoptotic Protein BID is Required for NOD-Mediated Inflammation and Innate Immunity
Wednesday, March 21 \| 5:00PM - 7:15PM Bcl-2 Protein Family Room: Van Horne C Speaker 5 of 6 Tomomi Kuwana, La Jolla Institute for Allergy and Immunology, USA Short Talk: Bax Forms Two Types of Pores in the Mitochondrial Outer Membrane: Slow- and Fast-Release
Wednesday, March 21 \| 5:00PM - 7:15PM Bcl-2 Protein Family Room: Van Horne C Speaker 6 of 6 Levi J. Beverly, University of Louisville, USA Short Talk: Combining Mouse Models, Biochemistry and Drug Screens to Understand the Role BCL2-Proteins in Human Cancer Initiation and Therapeutic Interventions
Wednesday, March 21 \| 5:00PM - 7:00PM The Interface between Mitochondria and the Endoplasmic Retic ulum This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 5 * Jodi Nunnari, University of California, Davis, USA
Wednesday, March 21 \| 5:00PM - 7:00PM The Interface between Mitochondria and the Endoplasmic Retic ulum This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 5 Gia K. Voeltz, University of Colorado Boulder, USA ER Tubules Mark Sites of Mitochondrial Division
Wednesday, March 21 \| 5:00PM - 7:00PM The Interface between Mitochondria and the Endoplasmic Retic ulum This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 5 György Hajnóczky, Thomas Jefferson University, USA Mechanisms of ER-Mitochondrial Local Communication
Wednesday, March 21 \| 5:00PM - 7:00PM The Interface between Mitochondria and the Endoplasmic Retic ulum This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 5 Francesco Cecconi, University of Rome Tor Vergata, Italy ER-Mitochondria Cross-Talk and the Clash between Autophagy and Cell Cycle Progression
Wednesday, March 21 \| 5:00PM - 7:00PM The Interface between Mitochondria and the Endoplasmic Retic ulum This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 5 Brendan J. Battersby, University of Helsinki, Finland Short Talk: Gimap3 Modifying mtDNA Segregation through Autophagy
Wednesday, March 21 \| 7:15PM - 8:00PM Social Hour with Lite Bites Room: Mezzanine 2
Wednesday, March 21 \| 7:30PM - 10:00PM Poster Session 2 Room: Mezzanine 2
Thursday, March 22 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Thursday, March 22 \| 8:00AM - 11:00AM Non-Cell Autonomous Mechanisms of Death Room: Van Horne C Speaker 1 of 6 * Kim McCall, Boston University, USA
Thursday, March 22 \| 8:00AM - 11:00AM Non-Cell Autonomous Mechanisms of Death Room: Van Horne C Speaker 2 of 6 Serge Przedborski, Columbia University, USA Astrocytes and Motor Neuron Degeneration
Thursday, March 22 \| 8:00AM - 11:00AM Non-Cell Autonomous Mechanisms of Death Room: Van Horne C Speaker 3 of 6 Gwenn A. Garden, University of Washington, USA Microglia Mediated Neurotoxicity is Downstream of Reactive Oxygen Species, p53 and microRNAs
Thursday, March 22 \| 8:00AM - 11:00AM Non-Cell Autonomous Mechanisms of Death Room: Van Horne C Speaker 4 of 6 Christian Münch, Harvard Medical School, The Harper Lab, USA Prion-Like Propagation of Mutant Superoxide Dismutase-1 Misfolding
Thursday, March 22 \| 8:00AM - 11:00AM Non-Cell Autonomous Mechanisms of Death Room: Van Horne C Speaker 5 of 6 Beata Jablonska, Children's National Medical Center, USA FoxO-Dependent Regulation of p27Kip1 Controls Oligodendrocyte Differentiation after Perinatal Hypoxia
Thursday, March 22 \| 8:00AM - 11:00AM Non-Cell Autonomous Mechanisms of Death Room: Van Horne C Speaker 6 of 6 Takeshi Watanabe, University of Tokyo, Japan Short Talk: Regulation of NR4A Nuclear Receptors by the ASK-p38 MAP Kinase Pathway-Dependent Phosphorylation
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 7 * Thomas Langer, CECAD Research Center, Germany
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 7 Janet M. Shaw, University of Utah, USA Identification of the Minimal Mitochondrial Fission Machinery in Yeast and Humans
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 7 Mike Ryan, Monash University, Australia Novel Mediators of Mitochondrial Morphology
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 7 Robert A. Screaton, Sunnybrook Research Institute, Canada Short Talk: Genome-Wide RNAi Screening Identifies Novel Regulators of Mitochondrial Morphology
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 7 Antonio Zorzano, Institute for Research in Biomedicine, Spain Mfn2 Links Mitochondrial and ER Function with Insulin Signaling
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 6 of 7 Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA Cell-Cycle Regulation of Mitochondrial Fusion and Fission
Thursday, March 22 \| 8:00AM - 11:30AM Mitochondrial Fusion and Fission: Mechanisms and Regulation This session is from Mitochondria Room: Van Horne A-B Speaker 7 of 7 Xiaodong Wang, BeiGene, China Mitochondrial Phosphatase PGAM5 Participates in Necrosis Execution
Thursday, March 22 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Thursday, March 22 \| 11:00AM - 1:00PM Poster Setup Room: Mezzanine 2
Thursday, March 22 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Thursday, March 22 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Thursday, March 22 \| 2:30PM - 3:30PM Workshop 2: Mitochondria on the Move This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 5 * György Hajnóczky, Thomas Jefferson University, USA
Thursday, March 22 \| 2:30PM - 3:30PM Workshop 2: Mitochondria on the Move This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 5 Konrad E. Zinsmaier, University of Arizona, USA Miro Controls Mitochondrial Transport, Structure, and Health in Axons through its GTPase or EF-Hand Domains
Thursday, March 22 \| 2:30PM - 3:30PM Workshop 2: Mitochondria on the Move This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 5 Richard A. Kahn, Emory University School of Medicine, USA Roles of the ARL2 GTPase at Mitochondria
Thursday, March 22 \| 2:30PM - 3:30PM Workshop 2: Mitochondria on the Move This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 5 Ghazaleh Ashrafi, Harvard University, USA Damage to Neuronal Mitochondria Arrests their Motility Prior to Mitophagy
Thursday, March 22 \| 2:30PM - 3:30PM Workshop 2: Mitochondria on the Move This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 5 Romain Cartoni, Children's Hospital Boston, Harvard Medical School, USA Co-Deletion of PTEN and SOCS3 Enhance Mitochondrial Transport after Axonal Injury
Thursday, March 22 \| 3:30PM - 4:30PM Workshop 3: Mitochondria and Endoplasmic Reticulum: Structur al and Functional Interplay This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 5 * Gia K. Voeltz, University of Colorado Boulder, USA
Thursday, March 22 \| 3:30PM - 4:30PM Workshop 3: Mitochondria and Endoplasmic Reticulum: Structur al and Functional Interplay This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 5 Laura L. Lackner, Northwestern University, USA An ER-Associated Mitochondria-Cortex Tether Functions in the Distribution and Inheritance of Mitochondria
Thursday, March 22 \| 3:30PM - 4:30PM Workshop 3: Mitochondria and Endoplasmic Reticulum: Structur al and Functional Interplay This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 5 Valentina Debattisti, Thomas Jefferson University, USA Marf, the Single Mitofusin of D. Melanogaster, is Selectively Complemented by Mitofusin 2
Thursday, March 22 \| 3:30PM - 4:30PM Workshop 3: Mitochondria and Endoplasmic Reticulum: Structur al and Functional Interplay This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 5 Heather M. Lamb, Johns Hopkins Bloomberg School of Public Health, USA Coexpression of Bax and Bcl-xL in the Secretory Pathway Alters ER Structure
Thursday, March 22 \| 3:30PM - 4:30PM Workshop 3: Mitochondria and Endoplasmic Reticulum: Structur al and Functional Interplay This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 5 Clement A. Gautier, Institut du Cerveau et de la moelle Epiniere, France Novel Role for Parkin in the Regulation of the Physical and Functional Interactions between Mitochondria and the Endoplasmic Reticulum
Thursday, March 22 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Thursday, March 22 \| 5:00PM - 7:15PM Cell Death Therapeutics Room: Van Horne C Speaker 1 of 6 * Douglas R. Green, St. Jude Children's Research Hospital, USA
Thursday, March 22 \| 5:00PM - 7:15PM Cell Death Therapeutics Room: Van Horne C Speaker 2 of 6 Carol M. Troy, Columbia University Medical Center, USA Intranasal Cell Permeant Caspase Inhibitors – Therapeutics for Cerebral Ischemia and other Neurologic Disorders
Thursday, March 22 \| 5:00PM - 7:15PM Cell Death Therapeutics Room: Van Horne C Speaker 3 of 6 Loren D. Walensky, Dana-Farber Cancer Institute, USA Mining the Repertoire of BH3 Interaction Sites for Next Generation Pro-Apoptotic Therapies
Thursday, March 22 \| 5:00PM - 7:15PM Cell Death Therapeutics Room: Van Horne C Speaker 4 of 6 Rajiv R. Ratan, Burke-Cornell Medical Research Institute, USA Epigenetic Modifiers Prevent Neurodegeneration: HDACs and Beyond
Thursday, March 22 \| 5:00PM - 7:15PM Cell Death Therapeutics Room: Van Horne C Speaker 5 of 6 Liane Wagner, University Medical Center Ulm, Germany Short Talk: Smac Mimetic Sensitizes Glioblastoma Cells to Temozolomide-Induced Apoptosis via Ripoptosome Formation
Thursday, March 22 \| 5:00PM - 7:15PM Cell Death Therapeutics Room: Van Horne C Speaker 6 of 6 Johannes Noack, DKFZ - German Cancer Research Center, Germany Short Talk: Combination of a Sphingosine Kinase Inhibitor and Temozolomide Results in a Strong Synergistic Cytotoxic Effect which Displays Features of Various Cell Death Pathways
Thursday, March 22 \| 5:00PM - 7:00PM The Interface between Mitochondria, Metabolism and Cell Deat h This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 5 * Paolo Bernardi, University of Padova Medical School, Italy
Thursday, March 22 \| 5:00PM - 7:00PM The Interface between Mitochondria, Metabolism and Cell Deat h This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 5 Vamsi K. Mootha, Massachusetts General Hospital, USA Discovery of the Mitochondrial Calcium Uniporter via Genomics
Thursday, March 22 \| 5:00PM - 7:00PM The Interface between Mitochondria, Metabolism and Cell Deat h This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 5 Eileen P. White, Rutgers Cancer Institute of New Jersey, USA Mitochondrial Control of Autophagy
Thursday, March 22 \| 5:00PM - 7:00PM The Interface between Mitochondria, Metabolism and Cell Deat h This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 5 Nika N. Danial, Dana-Farber Cancer Institute, USA Programming the Mitochondrial Carbon Substrate Utilization: A Role for BAD
Thursday, March 22 \| 5:00PM - 7:00PM The Interface between Mitochondria, Metabolism and Cell Deat h This session is from Mitochondria Room: Van Horne A-B Speaker 5 of 5 Christian Frezza, Hutchison/MRC Research Centre, UK Short Talk: Haem Oxygenase is Synthetically Lethal with the Tumor Suppressor Fumarate Hydratase
Thursday, March 22 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Mezzanine 2
Thursday, March 22 \| 7:30PM - 10:00PM Poster Session 3 Room: Mezzanine 2
Friday, March 23 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 1 of 7 * Heidi M. McBride, McGill University, Canada
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 2 of 7 Mondira Kundu, St. Jude Children's Hospital, USA ULK1: Linking Mitophagy with the Cellular Response to Stress
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 3 of 7 Koji Okamoto, Osaka University, Japan Molecular Mechanism of Mitochondria-specific Autophagy in Yeast
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 4 of 7 Paul A. Ney, New York Blood Center, USA A Single Amino in NIX is Essential for Mitochondrial Clearance in Reticulocytes
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 5 of 7 Richard J. Youle, NINDS, National Institutes of Health, USA Damage Control - How the Pink1/Parkin pathway can regulate removal of impaired mitochondria by autophagy
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 6 of 7 Rudolf J. Wiesner, University of Cologne, Germany Short Talk: Not the Assembly, the Stability of Respiratory Chain Complexes is Impaired by Nonsense Mutations in mtDNA Encoded Respiratory Chain Subunits
Friday, March 23 \| 8:00AM - 11:15AM Mitophagy/Quality Control (Joint) Room: Van Horne A-B Speaker 7 of 7 Matthew J. LaVoie, Brigham and Women's Hospital and Harvard Medical School, USA Short Talk: Parkin Ubiquitinates Bax to Regulate the Apoptotic Response of Mitochondria
Friday, March 23 \| 9:00AM - 9:20AM Coffee Break Room: Van Horne Foyer
Friday, March 23 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 1 of 8 * John J. Lemasters, Medical University of South Carolina, USA
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 2 of 8 Su-Jeong Kim, University of Southern California, USA Nuclear Translocation of DJ-1 during Oxidative Stress-Induced Neuronal Cell Death
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 3 of 8 Devrim Gozuacik, Sabanci University, Turkey MicroRNA Control of Autophagy
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 4 of 8 Charles A. O'Brien, University of Arkansas for Medical Sciences, USA Osteocyte Autophagy Declines with Age in Mice and Suppression of Osteocyte Autophagy Decreases Bone Mass and Mimics Skeletal Aging
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 5 of 8 Jennifer Martinez, NIEHS, National Institutes of Health, USA LC3-Associated Phagocytosis is Required for Efficient Clearance of Dead Cells
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 6 of 8 Babul Moni Ram, National Cancer Institute, USA Calcineurin Inhibitor Cyclosporine A Induces Endoplasmic Reticulum Stress Mediated Non Apoptotic Cell Death Response
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 7 of 8 Melanie J. Scott, University of Pittsburgh, USA Caspase-1-Dependent Mitophagy Regulates Liver Damage and Cell Death after Hemorrhagic Shock in Mice
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: Autophagy in Pathological Conditions Room: Van Horne C Speaker 8 of 8 Melissa Vos, University of Lübeck, Germany Vitamin K2 is a Mitochondrial Electron Carrier that Rescues Pink1 Deficiency
Friday, March 23 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Friday, March 23 \| 5:00PM - 7:00PM Use and Interpretation of Assays for Monitoring Mitophagy Room: Van Horne C Speaker 1 of 3 * Paul A. Ney, New York Blood Center, USA
Friday, March 23 \| 5:00PM - 7:00PM Use and Interpretation of Assays for Monitoring Mitophagy Room: Van Horne C Speaker 2 of 3 Orian S. Shirihai, University of California, Los Angeles, USA Live Imaging of Mitophagy in Mammalian Cells
Friday, March 23 \| 5:00PM - 7:00PM Use and Interpretation of Assays for Monitoring Mitophagy Room: Van Horne C Speaker 3 of 3 Hagai Abeliovich, Hebrew University of Jerusalem, Israel Mitophagy as a Quality Control Mechanism in Saccharomyces cerevisiae
Friday, March 23 \| 5:00PM - 7:00PM Mitochondrial Dynamics and Disease This session is from Mitochondria Room: Van Horne A-B Speaker 1 of 4 * Anu Suomalainen Wartiovaara, University of Helsinki, Finland
Friday, March 23 \| 5:00PM - 7:00PM Mitochondrial Dynamics and Disease This session is from Mitochondria Room: Van Horne A-B Speaker 2 of 4 Gerald W. Dorn, II, Washington University School of Medicine, USA The Varied Roles of Mitofusins in the Heart
Friday, March 23 \| 5:00PM - 7:00PM Mitochondrial Dynamics and Disease This session is from Mitochondria Room: Van Horne A-B Speaker 3 of 4 Vojo Deretic, University of New Mexico Health Sciences Center, USA Autophagy: An Immunity Paradigm with Mitochondria as a Centerpiece
Friday, March 23 \| 5:00PM - 7:00PM Mitochondrial Dynamics and Disease This session is from Mitochondria Room: Van Horne A-B Speaker 4 of 4 Michelle L. Boland, Medimmune, USA Short Talk: Bnip3 is Required to Prevent Hepatic Steatosis and Deficiencies in Gluconeogensis through Effects at the Mitochondria
Friday, March 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Mezzanine 2
Friday, March 23 \| 8:00PM - 11:00PM Entertainment Room: Mezzanine 2
Friday, March 23 \| 8:00PM - 11:00PM Cash Bar Room: Mezzanine 2
Saturday, March 24 \| 10:25AM - 10:25AM Departure *Session Chair.