Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
HIV Vaccines (2017C9)
HIV Vaccines (2016X8)
HIV Vaccines (2015X5)
HIV Vaccines: Adaptive Immunity and Beyond (2014X3)
HIV Vaccines (2013X2)

Web Desc
HIV Vaccines joint with Viral Immunity and Host Gene Influence Organizer(s): Gunilla B. Karlsson Hedestam, Andrew McMichael and Christopher J. Miller Date: March 21 - 26, 2012 Location: Keystone Resort, Keystone, CO, USA Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation. Sponsored by Sangamo BioSciences, Inc. Summary of Meeting: The 2012 Keystone Symposia meeting on HIV Vaccines will focus on basic aspects of immunology and HIV-1 virology to highlight issues that challenge the field. The genetic diversity of circulating HIV-1 variants puts extreme demands on the quality of the response a prophylactic vaccine will need to elicit. Most likely, conserved viral determinants need to be targeted and the response must be sustained over time. To facilitate a broad and open discussion around these topics, the symposium will convene expert investigators from the HIV-1 vaccine field as well as a number of basic immunologists. Aspects of natural HIV-1 infection of direct relevance to the development of a vaccine, such as viral transmission and viral escape from immune responses, will be addressed in joint sessions with the parallel meeting on Viral Immunity and Host Gene Influence. Speakers will also be invited to present in the workshops and in the oral sessions based on submitted abstracts. Global Health Travel Award Deadline: October 18 2011 Scholarship Deadline: November 21 2011 Discounted Abstract Deadline: November 21 2011 Abstract Deadline: December 22 2011 Discounted Registration Deadline: January 20 2012 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Crucell Ahmed Seif Baus We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI098441-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

HIV Vaccines

joint with Viral Immunity and Host Gene Influence

Organizer(s): Gunilla B. Karlsson Hedestam, Andrew McMichael and Christopher J. Miller

Date: March 21 - 26, 2012
Location: Keystone Resort, Keystone, CO, USA

Part of the Keystone Symposia Global Health Series, Supported by the Bill & Melinda Gates Foundation. Sponsored by Sangamo BioSciences, Inc.

Summary of Meeting:

The 2012 Keystone Symposia meeting on HIV Vaccines will focus on basic aspects of immunology and HIV-1 virology to highlight issues that challenge the field. The genetic diversity of circulating HIV-1 variants puts extreme demands on the quality of the response a prophylactic vaccine will need to elicit. Most likely, conserved viral determinants need to be targeted and the response must be sustained over time. To facilitate a broad and open discussion around these topics, the symposium will convene expert investigators from the HIV-1 vaccine field as well as a number of basic immunologists. Aspects of natural HIV-1 infection of direct relevance to the development of a vaccine, such as viral transmission and viral escape from immune responses, will be addressed in joint sessions with the parallel meeting on Viral Immunity and Host Gene Influence. Speakers will also be invited to present in the workshops and in the oral sessions based on submitted abstracts.

Global Health Travel Award Deadline: October 18 2011

Scholarship Deadline: November 21 2011

Discounted Abstract Deadline: November 21 2011

Abstract Deadline: December 22 2011

Discounted Registration Deadline: January 20 2012

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Crucell

Ahmed Seif Baus

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI098441-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Wednesday, March 21 \| 3:00PM - 7:30PM Registration Room: Longs Peak Foyer
Wednesday, March 21 \| 6:15PM - 7:15PM Refreshments Room: Longs Peak Foyer
Wednesday, March 21 \| 7:15PM - 7:30PM Welcome Address by the Organizers (Joint) Room: Columbine Ballroom Speaker 1 of 2 Gunilla B. Karlsson Hedestam, Karolinska Institutet, Sweden
Wednesday, March 21 \| 7:15PM - 7:30PM Welcome Address by the Organizers (Joint) Room: Columbine Ballroom Speaker 2 of 2 Laurence C. Eisenlohr, Children's Hospital of Philadelphia and University of Pennsylvania, USA
Wednesday, March 21 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Columbine Ballroom Speaker 1 of 4 * Naglaa Shoukry, University of Montreal Hospital Research Center, Canada
Wednesday, March 21 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Columbine Ballroom Speaker 2 of 4 * Andrew J. McMichael, Oxford University, UK
Wednesday, March 21 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Columbine Ballroom Speaker 3 of 4 Stanley M. Lemon, University of North Carolina at Chapel Hill, USA Divergent Infection Outcomes Marked by Similarities and Differences in Induction and Evasion of Interferon Responses by Hepatotropic RNA Viruses
Wednesday, March 21 \| 7:30PM - 9:30PM Keynote Session (Joint) Room: Columbine Ballroom Speaker 4 of 4 Joseph G. Sodroski, Dana-Farber Cancer Institute, USA Structure of the Membrane-Anchored HIV-1 Envelope Glycoprotein Trimer Complex by Cryoelectron Microscopy
Thursday, March 22 \| 7:00AM - 8:00AM Breakfast Room: Torreys Peak
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 1 of 7 * Daniel C. Douek, NIAID, National Institutes of Health, USA
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 2 of 7 * Barbara L. Shacklett, University of California, Davis, USA
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 3 of 7 Beatrice H. Hahn, University of Pennsylvania, USA Biology of Transmitted/Founder Viruses
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 4 of 7 Damien Tully, Ragon Institute of MGH, MIT and Harvard, USA A Deeper View of Transmitted/Founder Viruses during Acute HIV-1 Infection using 454 Whole Genome Deep Sequencing
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 5 of 7 Thomas J. Hope, Northwestern University, USA Defining the Mechanisms of Heterosexual HIV Transmission
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 6 of 7 Christopher J. Miller, University of California, Davis, USA Lessons Learned from Recapitulating the Step Trial in NHP
Thursday, March 22 \| 8:00AM - 11:00AM HIV-1/SIV Transmission Room: Longs/Grays Peaks Speaker 7 of 7 Kamini Gounder, Doris Duke Medical Research Institute, University of KwaZulu Natal, South Africa Short Talk: Viral Evolution and Immune Escape in Gag during Acute HIV-1 Subtype C Infection
Thursday, March 22 \| 8:00AM - 11:15AM Innate Immune Responses to Virus Infection This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 6 Jae U. Jung, Keck School of Medicine of University of Southern California, USA IFITM-Mediated Intracellular Anti-Viral Restriction
Thursday, March 22 \| 8:00AM - 11:15AM Innate Immune Responses to Virus Infection This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 6 * Mariapia A. Degli-Esposti, LEI, University of Western Australia, Australia NK Cell Immune Mechanisms in a Natural Host-Pathogen System
Thursday, March 22 \| 8:00AM - 11:15AM Innate Immune Responses to Virus Infection This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 6 Andrew G. Brooks, University of Melbourne, Australia Killer Immunoglobulin Receptor 3DL1-Mediated Recognition of HLA-A and –B Allotypes
Thursday, March 22 \| 8:00AM - 11:15AM Innate Immune Responses to Virus Infection This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 6 Luis J. Sigal, Fox Chase Cancer Center, USA Innate Immunity to Ectromelia Virus
Thursday, March 22 \| 8:00AM - 11:15AM Innate Immune Responses to Virus Infection This session is from Viral Immunity Room: Quandary Peak Speaker 5 of 6 Michael A. Schmid, Humabs – Vir Biotechnology, Switzerland Short Talk: Dendritic Cells and the Immune Response to Dengue Virus Infection in the Skin
Thursday, March 22 \| 8:00AM - 11:15AM Innate Immune Responses to Virus Infection This session is from Viral Immunity Room: Quandary Peak Speaker 6 of 6 Béhazine Combadiere, Centre d'Immunologie et des Maladies Infectieuses, France Short Talk: Neutrophils Drag and Drop Antigen from the Dermis to the Bone Marrow Initiating an Alternative Source of Long-Lived Memory CD8+ T Cells
Thursday, March 22 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Thursday, March 22 \| 11:00AM - 1:00PM Poster Setup Room: Torreys Peak
Thursday, March 22 \| 11:00AM - 12:30PM Hands On Computer Workshop on Los Alamos SEQUENCE DATABASE a nd Tools Room: Castle Peaks Maximum attendance: 60. Interested participants must sign up at the meeting on a first-come, first-serve basis. Instructors: Brian Foley, Bette Korber and Carla Kuiken.
Thursday, March 22 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Thursday, March 22 \| 1:00PM - 10:00PM Poster Viewing Room: Torreys Peak
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 1 of 10 * Eric Hunter, Emory University, USA
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 2 of 10 * Christopher J. Miller, University of California, Davis, USA
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 3 of 10 Debby Basu, Emory University, USA Intra-Subtype C HIV-1 Superinfection Occurs Prior to Robust Neutralizing Antibody Responses in the Newly Infected Partner
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 4 of 10 Katja Pfafferott, Weatherall Institute of Molecular Medicine, UK Analysis of Two Clade A Transmission Pairs with Contrasting Clinical Outcomes Suggests Contributions of the Founder Virus and Host CD8 T Cell Response to Set-Point Viremia
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 5 of 10 Rama Rao Amara, Emory University, USA GM-CSF Expressed by DNA but Not MVA Enhances Prevention of Acquisition by a Heterologous Mucosal Challenge
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 6 of 10 Shari N. Gordon, NCI, National Institutes of Health, USA Human Papillomavirus Pseudovirion Vaccines Delivering SIV DNA Partially Protects from Mucosal SIVmac251 Infection
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 7 of 10 Brian Moldt, The Scripps Research Institute, USA Non-Fucosylated b12 has Enhanced FcyRIIIa-Mediated Antiviral Activity in vitro but Not Improved Protection against Mucosal SHIV Challenge in Macaques
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 8 of 10 Amarendra Pegu, NIAID, National Institutes of Health, USA VRC01 Provides Sterilizing Protection to Non Human Primates from Mucosal SHIV Challenges
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 9 of 10 Adrienne E. Swanstrom, University of Pennsylvania, USA In vitro and in vivo Characterization of a Novel Variant of SIVmac239 Lacking CD4 Tropism
Thursday, March 22 \| 2:30PM - 4:30PM Workshop 1: HIV-1/SIV Transmission and NHP Protection Studie s Room: Longs/Grays Peaks Speaker 10 of 10 Liang Shang, University of Minnesota, USA Natural Killer Cells Are Critical to Control Viral Infection in the Female Genital Tract of Rhesus Macaque after SIV Vaginal Challenge
Thursday, March 22 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Thursday, March 22 \| 5:00PM - 7:00PM B Cells and Neutralizing Antibodies Room: Longs/Grays Peaks Speaker 1 of 6 * Michel C. Nussenzweig, HHMI/Rockefeller University, USA
Thursday, March 22 \| 5:00PM - 7:00PM B Cells and Neutralizing Antibodies Room: Longs/Grays Peaks Speaker 2 of 6 * Michael B. Zwick, The Scripps Research Institute, USA
Thursday, March 22 \| 5:00PM - 7:00PM B Cells and Neutralizing Antibodies Room: Longs/Grays Peaks Speaker 3 of 6 David M. Tarlinton, Monash University, Australia Memory B Cell and Plasma Cell Development in Response to Vaccination
Thursday, March 22 \| 5:00PM - 7:00PM B Cells and Neutralizing Antibodies Room: Longs/Grays Peaks Speaker 4 of 6 Dennis R. Burton, The Scripps Research Institute, USA Neutralizing Antibody Targets on the HIV-1 Spike
Thursday, March 22 \| 5:00PM - 7:00PM B Cells and Neutralizing Antibodies Room: Longs/Grays Peaks Speaker 5 of 6 Gary J. Nabel, Sanofi, USA Generation of Broadly Neutralizing Antibodies in an AIDS Vaccine: The End of the Beginning
Thursday, March 22 \| 5:00PM - 7:00PM B Cells and Neutralizing Antibodies Room: Longs/Grays Peaks Speaker 6 of 6 Jinghe Huang, NIAID, National Institutes of Health, USA Short Talk: Isolation of a Broad, Potent, MPER-Specific Monoclonal Antibody with Novel Binding Characteristics
Thursday, March 22 \| 5:00PM - 7:00PM Systems Approaches to Virus-Host Interactions This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 4 Alan Aderem, Center for Infectious Disease Research, USA A Systems Approach to Dissecting Immunity
Thursday, March 22 \| 5:00PM - 7:00PM Systems Approaches to Virus-Host Interactions This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 4 * Ralph S. Baric, University of North Carolina at Chapel Hill, USA Systems Genetics and Respiratory Virus Pathogenomics
Thursday, March 22 \| 5:00PM - 7:00PM Systems Approaches to Virus-Host Interactions This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 4 Alison Simmons, Weatherall Institute of Molecular Medicine, UK Early Host Responses to HIV Infection
Thursday, March 22 \| 5:00PM - 7:00PM Systems Approaches to Virus-Host Interactions This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 4 Nathan P. Croft, University of Melbourne, Australia Short Talk: Quantitative Kinetics of Antigen Presentation during Viral Infection
Thursday, March 22 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys Peak
Thursday, March 22 \| 7:30PM - 10:00PM Poster Session 1 Room: Torreys Peak
Friday, March 23 \| 7:00AM - 8:00AM Breakfast Room: Torreys Peak
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 1 of 8 * Mark Connors, NIAID, National Institutes of Health, USA
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 2 of 8 * Kevin L. Legge, University of Iowa Carver College of Medicine, USA
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 3 of 8 Laurence C. Eisenlohr, Children's Hospital of Philadelphia and University of Pennsylvania, USA MHC Class II-Restricted Processing Pathways for Viral Antigens
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 4 of 8 Chris C. Norbury, Pennsylvania State University Medical School, USA Short Talk: Assessing the Role of APC Phenotype and Maturation Status upon the Contribution of Direct and Cross Antigen Presentation during a Natural Virus Infection
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 5 of 8 Gunilla B. Karlsson Hedestam, Karolinska Institutet, Sweden Properties of B Cell Responses Elicited By Soluble HIV-1 Env Trimers
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 6 of 8 Laura E. McCoy, University College London, UK Short Talk: Potent Multi-Clade Neutralization of HIV-1 by a Llama VHH Antibody Induced by Immunization
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 7 of 8 Marc K. Jenkins, University of Minnesota Medical School, USA Maintenance of Protective CD4+ “Memory” T Cells during Persistent Phagosomal Infection
Friday, March 23 \| 8:00AM - 11:15AM Stimulation of Adaptive Immune Responses (Joint) Room: Columbine Ballroom Speaker 8 of 8 David Price, Cardiff University School of Medicine, UK The Clonotypic Basis of Adaptive T Cell Immunity
Friday, March 23 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Friday, March 23 \| 11:15AM - 1:00PM Poster Setup Room: Torreys Peak
Friday, March 23 \| 11:15AM - 12:45PM Hands On Computer Workshop on Los Alamos IMMUNOLOGY DATABASE and Tools Room: Castle Peaks Maximum attendance: 60. Interested participants must sign up at the meeting on a first-come, first-serve basis. Instructors: Brian Foley, Bette Korber and Carla Kuiken.
Friday, March 23 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Friday, March 23 \| 1:00PM - 10:00PM Poster Viewing Room: Torreys Peak
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 1 of 10 * Nicole A. Doria-Rose, NIAID, National Institutes of Health, USA
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 2 of 10 * James A. Hoxie, University of Pennsylvania, USA
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 3 of 10 Torben Schiffner, The Scripps Research Institute, USA Modulating Immunogenicity by Chemical Modification of gp140
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 4 of 10 Mattias Forsell, Umeå University, Sweden Targeted Immunosilencing Reveals Independent Regulation of Epitope Specific B Cell Responses to HIV-1 Env
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 5 of 10 Elise Landais, International AIDS Vaccine Initiative, USA Development of Broadly Neutralizing Antibody Responses in a Large Sub-Saharan HIV Primary Infection Cohorts
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 6 of 10 Jason S. McLellan, University of Texas at Austin, USA Structural and Biophysical Studies of Antibodies Isolated from RV144 Vaccinees
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 7 of 10 Lawrence S. Shapiro, Columbia University, USA Deep Sequencing with Longitudinal Sampling of a VRC01-Like-Antibody Response in a Chronically Infected Individual
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 8 of 10 Jordan R. Willis, Vanderbilt University, USA Structure Analysis of Healthy Donor Repertoire Confers Sequences that Match Long Complementary Determining Regions of Broadly Neutralizing Antibodies
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 9 of 10 Samantha J. Hoot, Seattle Biomedical Research Institute, USA Interaction of Germline Precursors to Broadly Neutralizing Anti-CD4 Binding Site Antibodies with HIV-1 Envelope Glycoproteins
Friday, March 23 \| 2:30PM - 4:30PM Workshop 2: B Cells and Neutralizing Antibodies Speaker 10 of 10 M. Gordon Joyce, US Military HIV Research Program, USA Structures of Reverted Germline VRC01-Like Antibodies Guide HIV-1 Immunogen Design
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 8 Sophie Hambleton, Newcastle University, UK A Defect in Type I Interferon Signaling Causes Severe Susceptibility to Some, but Not All, Viral Infections in Humans
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 8 Tao Peng, University of Washington, USA System Biology Approaches to Dissect Immune-Surveillance Roles of CD8+ Cells at Mucosal Surface during HSV-2 Reactivation
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 8 Daniela Weiskopf, La Jolla Institute for Immunology, USA Proteome Wide Mapping of Dengue Virus-Specific T Cell Responses in Human Donors Reveals Antigenic Hot Spots and a Dominance of HLA B Restricted Responses
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 8 * Michelle L. Baker, CSIRO Livestock Industries, Australia Immunology of an Important Viral Reservoir, the Australian Black Flying Fox
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 5 of 8 * Andrew J. Yates, Columbia University, USA The Race for the Prize – Surveillance Strategies for the Efficient Induction of T Cell Responses
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 6 of 8 Allison M. W. Malloy, Uniformed Services University of the Health Sciences, USA CD8+ T Cell Epitope Hierarchy is Established during the Neonatal Period in Respiratory Syncytial Virus-Infected Mice
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 7 of 8 Christopher Lupfer, St. Jude Children's Research Hospital, USA T Cell Intrinsic Role of Nod2 in Cellular Immunity to Virus Infection
Friday, March 23 \| 2:30PM - 4:30PM Workshop 1 This session is from Viral Immunity Room: Quandary Peak Speaker 8 of 8 Shiki Takamura, Kinki University Faculty of Medicine, Japan CD69 Controls a Balance between S1P- and CXCL16-Induced Chemotaxes during the Process of Memory CD8+ T Cell Recruitment to the Lung Airways
Friday, March 23 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Friday, March 23 \| 5:00PM - 7:00PM Cellular Immunity against HIV/SIV - Messages for Vaccines Room: Longs/Grays Peaks Speaker 1 of 6 * Nilu Goonetilleke, University of North Carolina at Chapel Hill, USA
Friday, March 23 \| 5:00PM - 7:00PM Cellular Immunity against HIV/SIV - Messages for Vaccines Room: Longs/Grays Peaks Speaker 2 of 6 * Guido Ferrari, Duke University Medical Center, USA
Friday, March 23 \| 5:00PM - 7:00PM Cellular Immunity against HIV/SIV - Messages for Vaccines Room: Longs/Grays Peaks Speaker 3 of 6 Marcus Altfeld, Heinrich-Pette-Institute, Germany NK Cell Mediated Immune Pressure in HIV-1 Infection
Friday, March 23 \| 5:00PM - 7:00PM Cellular Immunity against HIV/SIV - Messages for Vaccines Room: Longs/Grays Peaks Speaker 4 of 6 Stephen J. Kent, University of Melbourne, Australia ADCC Activity against HIV
Friday, March 23 \| 5:00PM - 7:00PM Cellular Immunity against HIV/SIV - Messages for Vaccines Room: Longs/Grays Peaks Speaker 5 of 6 David I. Watkins, University of Miami, USA SIV-Specific T Cell Responses
Friday, March 23 \| 5:00PM - 7:00PM Cellular Immunity against HIV/SIV - Messages for Vaccines Room: Longs/Grays Peaks Speaker 6 of 6 Alessandra Noto, Lausanne University Hospital, Switzerland Short Talk: Loss of Id2 during Chronic HIV Infection is Mediated by PD-1 Triggering and is Responsible for HIV-Specific CD8+ T Cell Exhaustion
Friday, March 23 \| 5:00PM - 7:00PM Adaptive Immunity: Regulating T Cell Function at the Levels of Epigenetics and TCR Activation This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 4 Pedro R. Lowenstein, University of Michigan School of Medicine, USA CD8 TcR Synapses in vitro and in vivo
Friday, March 23 \| 5:00PM - 7:00PM Adaptive Immunity: Regulating T Cell Function at the Levels of Epigenetics and TCR Activation This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 4 Heather D. Hickman, NIAID, National Institutes of Health, USA Intravital Imaging of CD8+ T Cell Activation after Viral Infection
Friday, March 23 \| 5:00PM - 7:00PM Adaptive Immunity: Regulating T Cell Function at the Levels of Epigenetics and TCR Activation This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 4 * Stephen J. Turner, Monash University, Australia Epigenetic Regulation of Virus-Specific CD8+ T Cell Responses
Friday, March 23 \| 5:00PM - 7:00PM Adaptive Immunity: Regulating T Cell Function at the Levels of Epigenetics and TCR Activation This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 4 J. Scott Hale, University of Utah, USA Short Talk: Distinct Memory CD4 T Cells with Commitment to the T Follicular Helper and Th1 Lineages
Friday, March 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys Peak
Friday, March 23 \| 7:30PM - 10:00PM Poster Session 2 Room: Torreys Peak
Saturday, March 24 \| 7:00AM - 8:00AM Breakfast Room: Torreys Peak
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 1 of 8 * Todd M. Allen, Ragon Institute of MGH, MIT and Harvard, USA
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 2 of 8 Ted C. Pierson, NIAID, National Institutes of Health, USA A Dynamic Landscape for Antibody-Mediated Neutralization and Enhancement of Flavivirus Infection
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 3 of 8 * Klaus Früh, Oregon Health & Science University, USA Evasion of T Cell Responses by Cytomegalovirus
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 4 of 8 Hanneke Schuitemaker, Janssen Vaccines & Prevention B.V., Netherlands HIV-1 Dynamics in Relation to Cross-Reactive Neutralizing Humoral Immunity
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 5 of 8 Nilu Goonetilleke, University of North Carolina at Chapel Hill, USA Short Talk: T Cell Immunodominance, Breadth and Epitope Entropy are the Major Determinants of Virus Escape in Acute HIV-1 Infection
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 6 of 8 Andrew J. McMichael, Oxford University, UK HIV-1 Escape from CD8+ T Cell Recognition
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 7 of 8 Timothy E. Dudek, Ragon Institute of MGH, MIT and Harvard, USA Short Talk: Accurate Recapitulation of Human Acute-Phase HIV-Specific CD8+ T-Cell Responses and Viral Evolution in Humanized BLT Mice
Saturday, March 24 \| 8:00AM - 11:15AM Immune Evasion and Subversion (Joint) Room: Columbine Ballroom Speaker 8 of 8 Kia Katchar, Ragon Institute of MGH, MIT and Harvard, USA Short Talk: Adaptation of Hepatitis C Virus (HCV) to KIR-Associated Immune Pressures
Saturday, March 24 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Saturday, March 24 \| 11:15AM - 11:45AM The Grant Submission Process at NIH/NIAID (Joint) Room: Columbine Ballroom The presentation will introduce the NIH/NIAID grant submission process and describe some grants available to new investigators. Speaker 1 of 1 Cheryl Lapham, NIAID, National Institutes of Health, USA
Saturday, March 24 \| 11:15AM - 1:00PM Poster Setup Room: Torreys Peak
Saturday, March 24 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Saturday, March 24 \| 1:00PM - 10:00PM Poster Viewing Room: Torreys Peak
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 1 of 9 * Richard A. Koup, NIAID, National Institutes of Health, USA
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 2 of 9 * Bette Tina Marie Korber, Los Alamos National Laboratory, USA A Comparison of Conserved Region versus Full-Length Protein T Cell Vaccines in Rhesus Monkeys Reveals No Evidence for Immunofocusing
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 3 of 9 Karthik Shekhar, Massachusetts Institute of Technology, USA Collective Evolution in HIV Proteins Reveals Strategies for Rational HIV Vaccine Design
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 4 of 9 Tomas Hanke, University of Oxford, UK Immunogenicity of a Universal HIV-1 Vaccine Vectored by DNA, MVA and ChAdV-63 in a Phase I/IIa Clinical Trial
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 5 of 9 Daniel Claiborne, Ragon Institute of MGH, MIT, and Harvard, USA Rare HLA-Associated Gag Polymorphisms Dramatically Reduce Replicative Capacity of Transmitted Founder Viruses and Modulate Set Point Viral Load
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 6 of 9 Sylvie Le Gall, Massachusetts General Hospital, Harvard Medical School, USA Sequence Signatures Define HIV Antigen Processing Mutations Leading to Immune Escape at the Population Level
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 7 of 9 Lydie Trautmann, US Military HIV Research Program, USA Dissecting Function, Memory Generation, and TCR Repertoire of Effector CD8 T cells in Primary HIV Infection and other Acute Viral Infections
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 8 of 9 Srinika R. F. Ranasinghe, Ragon Institute of MGH, MIT and Harvard, USA Promiscuity in Peptide-HLA Class II Interactions Impact HIV Immune Control
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 3: Cellular Immunity against SIV/HIV Room: Longs/Grays Peaks Speaker 9 of 9 LaTonya D. Williams, Duke University Medical Center, USA CD4-Like Immunologic Function by IL-21-Producing CD8 T Cells in HIV-Infected Individuals
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 8 Christopher Brooke, NIAID, National Institutes of Health, USA Nine Out of Ten Influenza A Virions Can Be Wrong: The Cost of Segmentation
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 8 Michael E. Wortzman, University of Toronto, Canada Role of CD8 T Cell Intrinsic TNF in Enhancing the Contraction of Short-Lived Effector Cells during Respiratory Influenza Virus Infection
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 8 Matthieu Daugan, INRS-Institut Armand-Frappier, Canada Mechanisms Implicated in the Late Appearance of Neutralizing Antibodies against Lymphocytic Choriomeningitis Virus
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 8 * Mario L. Santiago, University of Colorado Denver, USA A Single Nucleotide Polymorphism in Tetherin Promotes Retrovirus Restriction in vivo
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 5 of 8 Deepak Mittal, University of Queensland Diamantina Institute, Australia Mechanisms of Local Immune Suppression in HPV E7 Expressing Skin
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 6 of 8 * Pinghui Feng, University of Southern California, USA A Herpesvirus Selectively Hijacks an Innate Immune Signal Pathway to Enable Viral Transcriptional Activation and Disable Host Antiviral Cytokine Production
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 7 of 8 Amy Haseley, Ohio State University, USA Secreted ECM Protein CCN1 Limits Oncolytic HSV-1 Efficacy for Glioma
Saturday, March 24 \| 2:30PM - 4:30PM Workshop 2 This session is from Viral Immunity Room: Quandary Peak Speaker 8 of 8 Patrick C. Rämer, University of Zürich, Switzerland Identification of Viral Tumor-Suppressor Using a Humanized Mouse Model of EBV Infection
Saturday, March 24 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Saturday, March 24 \| 5:00PM - 7:00PM Update from Clinical Trials of HIV-1 Vaccines Room: Longs/Grays Peaks Speaker 1 of 6 * Lawrence Corey, Fred Hutchinson Cancer Research Center, USA
Saturday, March 24 \| 5:00PM - 7:00PM Update from Clinical Trials of HIV-1 Vaccines Room: Longs/Grays Peaks Speaker 2 of 6 * Amapola Manrique, Global HIV Vaccine Enterprise, USA
Saturday, March 24 \| 5:00PM - 7:00PM Update from Clinical Trials of HIV-1 Vaccines Room: Longs/Grays Peaks Speaker 3 of 6 Nicole Frahm, Bill & Melinda Gates Medical Research Institute, USA The HIV Vaccine Landscape after Step and RV144
Saturday, March 24 \| 5:00PM - 7:00PM Update from Clinical Trials of HIV-1 Vaccines Room: Longs/Grays Peaks Speaker 4 of 6 Nelson L. Michael, Walter Reed Army Institute of Research, USA Thai Phase III Update. RV144 Follow-up: Antigenicity, Correlates, and Sieve Analysis
Saturday, March 24 \| 5:00PM - 7:00PM Update from Clinical Trials of HIV-1 Vaccines Room: Longs/Grays Peaks Speaker 5 of 6 Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA Antibodies, Variable Regions, and the RV144 Vaccine Trial Results
Saturday, March 24 \| 5:00PM - 7:00PM Update from Clinical Trials of HIV-1 Vaccines Room: Longs/Grays Peaks Speaker 6 of 6 Amy W. Chung, Ragon Institute of MGH, MIT & Harvard, USA Short Talk: RV144 Vaccine Induces a Differential Antibody Effector Function Profile in Comparison to VAX003
Saturday, March 24 \| 5:00PM - 7:00PM Immunity to Chronic and Persistent Viral Infections This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 4 Mehrdad Matloubian, University of California, San Francisco, USA Role of Innate Sensing Pathways in Chronic Viral Infections
Saturday, March 24 \| 5:00PM - 7:00PM Immunity to Chronic and Persistent Viral Infections This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 4 Barbara Rehermann, NIDDK, National Institutes of Health, USA Natural Killer Cell Function in Hepatitis C Virus Infection
Saturday, March 24 \| 5:00PM - 7:00PM Immunity to Chronic and Persistent Viral Infections This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 4 Christopher M. Snyder, Thomas Jefferson University, USA Short Talk: Small Populations of Memory-Like CD8+ T Cells Undergo Memory Inflation during MCMV Infection
Saturday, March 24 \| 5:00PM - 7:00PM Immunity to Chronic and Persistent Viral Infections This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 4 * Andrea Lynn Cox, Johns Hopkins University, USA The Missing Link between Inflammasome Complex Activation and Adaptive Immune Responses in the Transition from Acute to Chronic HCV Infection
Saturday, March 24 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys Peak
Saturday, March 24 \| 7:30PM - 10:00PM Poster Session 3 Room: Torreys Peak
Sunday, March 25 \| 7:00AM - 8:00AM Breakfast Room: Torreys Peak
Sunday, March 25 \| 8:00AM - 11:00AM Effective Immune Responses in Animal Models Room: Longs/Grays Peaks Speaker 1 of 6 * James E. Robinson, Tulane University Health Sciences Center, USA
Sunday, March 25 \| 8:00AM - 11:00AM Effective Immune Responses in Animal Models Room: Longs/Grays Peaks Speaker 2 of 6 * Nancy R. Miller, NIAID, National Institutes of Health, USA
Sunday, March 25 \| 8:00AM - 11:00AM Effective Immune Responses in Animal Models Room: Longs/Grays Peaks Speaker 3 of 6 Jason M. Brenchley, NIAID, National Institutes of Health, USA Microbial Translocation, Immune Activation, and Disease Progression
Sunday, March 25 \| 8:00AM - 11:00AM Effective Immune Responses in Animal Models Room: Longs/Grays Peaks Speaker 4 of 6 Poonam Pegu, NCI, National Institutes of Health, USA Short Talk: Mucosal Transmission of a Limited Number of SIVmac251 Variants in Macaques Recapitulates HIV Vaccine Efficacy in Humans
Sunday, March 25 \| 8:00AM - 11:00AM Effective Immune Responses in Animal Models Room: Longs/Grays Peaks Speaker 5 of 6 Richard T. Wyatt, IAVI Neutralizing Antibody Center, The Scripps Research Institute, USA Analysis of HIV-1 Env and Elicited Antibody Responses for Improved Immunogen Design
Sunday, March 25 \| 8:00AM - 11:00AM Effective Immune Responses in Animal Models Room: Longs/Grays Peaks Speaker 6 of 6 Nancy L. Haigwood, Oregon Health & Science University, USA Clues to Understanding the Role and Impact of Eliciting Neutralizing Antibodies
Sunday, March 25 \| 8:00AM - 11:15AM Immune Tailoring in Non-Lymphoid Tissues This session is from Viral Immunity Room: Quandary Peak Speaker 1 of 6 Mark T. Heise, University of North Carolina at Chapel Hill, USA Systems Genetics and Regulation of Virus-Induced Inflammatory Responses
Sunday, March 25 \| 8:00AM - 11:15AM Immune Tailoring in Non-Lymphoid Tissues This session is from Viral Immunity Room: Quandary Peak Speaker 2 of 6 David L. Woodland, Keystone Symposia on Molecular and Cellular Biology, USA Lung Specific Recruitment of Virus-Specific T Cells during Acute Respiratory Infection
Sunday, March 25 \| 8:00AM - 11:15AM Immune Tailoring in Non-Lymphoid Tissues This session is from Viral Immunity Room: Quandary Peak Speaker 3 of 6 Yoshimasa Takahashi, National Institute of Infectious Diseases, Japan Short Talk: Memory B Cells in the Lung Participate in Protective Humoral Immune Responses to Pulmonary Influenza Virus Reinfection
Sunday, March 25 \| 8:00AM - 11:15AM Immune Tailoring in Non-Lymphoid Tissues This session is from Viral Immunity Room: Quandary Peak Speaker 4 of 6 * Cornelia C. Bergmann, Cleveland Clinic Foundation, USA Cell Type-Specific Immune Regulation during Viral Encephalomyelitis
Sunday, March 25 \| 8:00AM - 11:15AM Immune Tailoring in Non-Lymphoid Tissues This session is from Viral Immunity Room: Quandary Peak Speaker 5 of 6 Jasmin Herz, University of Virginia, USA Short Talk: Dynamics of Memory T Cells Clearing a Persistent Infection in the Absence of Severe Tissue Injury
Sunday, March 25 \| 8:00AM - 11:15AM Immune Tailoring in Non-Lymphoid Tissues This session is from Viral Immunity Room: Quandary Peak Speaker 6 of 6 Robert L. Hendricks, University of Pittsburgh, USA Manipulating HSV-Specific CD8+ T Cell Function to Control Latent Infections in Sensory Gangli
Sunday, March 25 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Sunday, March 25 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Sunday, March 25 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Sunday, March 25 \| 5:00PM - 7:00PM New Concepts Guiding Vaccine Development (Joint) Room: Columbine Ballroom Speaker 1 of 5 * Gunilla B. Karlsson Hedestam, Karolinska Institutet, Sweden
Sunday, March 25 \| 5:00PM - 7:00PM New Concepts Guiding Vaccine Development (Joint) Room: Columbine Ballroom Speaker 2 of 5 * Laurence C. Eisenlohr, Children's Hospital of Philadelphia and University of Pennsylvania, USA
Sunday, March 25 \| 5:00PM - 7:00PM New Concepts Guiding Vaccine Development (Joint) Room: Columbine Ballroom Speaker 3 of 5 Shane Crotty, La Jolla Institute for Immunology, USA Designing Vaccines: Follicular Helper CD4 T Cells and their Roles in Generating Neutralizing Antibody Responses
Sunday, March 25 \| 5:00PM - 7:00PM New Concepts Guiding Vaccine Development (Joint) Room: Columbine Ballroom Speaker 4 of 5 Robert A. Seder, NIAID, National Institutes of Health, USA Impact of Adjuvants on HIV-Specific Immune Responses
Sunday, March 25 \| 5:00PM - 7:00PM New Concepts Guiding Vaccine Development (Joint) Room: Columbine Ballroom Speaker 5 of 5 Michel C. Nussenzweig, HHMI/Rockefeller University, USA Human Antibodies to HIV
Sunday, March 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Torreys Peak
Sunday, March 25 \| 8:00PM - 11:00PM Entertainment Room: Torreys Peak
Sunday, March 25 \| 8:00PM - 11:00PM Cash Bar Room: Torreys Peak
Monday, March 26 \| 10:25AM - 10:25AM Departure *Session Chair.