Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
The Ins and Outs of Viral Infection: Entry, Assembly, Exit and Spread (2014C6)

Web Desc
Cell Biology of Virus Entry, Replication and Pathogenesis joint with Frontiers in HIV Pathogenesis, Therapy and Eradication Organizer(s): Michael Farzan, Benhur Lee and Judith M. White Date: March 26 - 31, 2012 Location: Whistler Conference Centre, Whistler, BC, Canada Sponsored by Gilead Sciences, Inc. and MedImmune For important information on the coronavirus, please click here Summary of Meeting: This meeting will highlight recent advances in virus infection pathways, and in the cellular responses to viral infection. The meeting features multiple stages of the viral lifecycle analyzed using a broad array of techniques and levels of analysis. A novel feature of this meeting is that it will be held concurrently with the Keystone Symposia meeting on Frontiers in HIV Pathogenesis, Therapy and Eradication and will, therefore, focus on maximizing exchange between the HIV community and the broader community of virologists. An explicit goal is to bring together and promote potential synergies among researchers who might not otherwise interact in more specialized meetings. A classic, almost paradigmatic, example of the power of this cross-talk is the contribution of studies of influenza A virus hemagglutinin to our understanding of the HIV-1 entry process, and the subsequent contribution of both systems to our understanding of type I fusion, type II fusion and the entry processes of non-enveloped viruses. Accordingly, two common sessions will focus on the retroviral entry process and its inhibition, followed by talks featuring a broader survey of viral entry, replication, structural and systems approaches to virology, host immune evasion and therapeutics. Scholarship Deadline: November 29 2011 Discounted Abstract Deadline: November 29 2011 Abstract Deadline: January 4 2012 Discounted Registration Deadline: January 26 2012 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: MedImmune Merck Research Laboratories Wen Chang, in memory of Frank Fenner We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI098314-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Cell Biology of Virus Entry, Replication and Pathogenesis

joint with Frontiers in HIV Pathogenesis, Therapy and Eradication

Organizer(s): Michael Farzan, Benhur Lee and Judith M. White

Date: March 26 - 31, 2012
Location: Whistler Conference Centre, Whistler, BC, Canada

Sponsored by Gilead Sciences, Inc. and MedImmune

For important information on the coronavirus, please click here

Summary of Meeting:

This meeting will highlight recent advances in virus infection pathways, and in the cellular responses to viral infection. The meeting features multiple stages of the viral lifecycle analyzed using a broad array of techniques and levels of analysis. A novel feature of this meeting is that it will be held concurrently with the Keystone Symposia meeting on Frontiers in HIV Pathogenesis, Therapy and Eradication and will, therefore, focus on maximizing exchange between the HIV community and the broader community of virologists. An explicit goal is to bring together and promote potential synergies among researchers who might not otherwise interact in more specialized meetings. A classic, almost paradigmatic, example of the power of this cross-talk is the contribution of studies of influenza A virus hemagglutinin to our understanding of the HIV-1 entry process, and the subsequent contribution of both systems to our understanding of type I fusion, type II fusion and the entry processes of non-enveloped viruses. Accordingly, two common sessions will focus on the retroviral entry process and its inhibition, followed by talks featuring a broader survey of viral entry, replication, structural and systems approaches to virology, host immune evasion and therapeutics.

Scholarship Deadline: November 29 2011

Discounted Abstract Deadline: November 29 2011

Abstract Deadline: January 4 2012

Discounted Registration Deadline: January 26 2012

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

MedImmune

Merck Research Laboratories

Wen Chang, in memory of Frank Fenner

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI098314-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Monday, March 26 \| 3:00PM - 7:30PM Registration Room: Grand Foyer
Monday, March 26 \| 6:15PM - 7:15PM Refreshments Room: Grand Foyer
Monday, March 26 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sea to Sky B/C Speaker 1 of 4 * Alan N. Engelman, Dana-Farber Cancer Institute, USA
Monday, March 26 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sea to Sky B/C Speaker 2 of 4 * Michael Farzan, The Scripps Research Institute, USA
Monday, March 26 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sea to Sky B/C Speaker 3 of 4 Robert F. Siliciano, Johns Hopkins University School of Medicine, USA Understanding How Antiretroviral Therapy for HIV Infection Really Works
Monday, March 26 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Sea to Sky B/C Speaker 4 of 4 Stephen C. Harrison, Harvard Medical School, USA Mechanisms of Virus Entry
Tuesday, March 27 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A, Garibaldi B/C
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 1 of 7 * Peter D. Kwong, NIAID, National Institutes of Health, USA
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 2 of 7 Sriram Subramaniam, University of British Columbia, Canada Structure of HIV and SIV Envelope Glycoproteins and Mechanisms of Viral Entry
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 3 of 7 Kelly K. Lee, University of Washington, USA Short Talk: Solution Structure and Conformational Dynamics in Full-Length, Glycosylated HIV Gp120
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 4 of 7 Thomas J. Hope, Northwestern University, USA HIV in the Cytoplasm: How Can Early Events Influence Late Outcomes?
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 5 of 7 Michael J. Root, Thomas Jefferson University, USA HIV-1 gp41 Structural Changes Associated with Viral Membrane Fusion
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 6 of 7 Clare Jolly, University College London, UK Cell-Cell Transfer of HIV-1
Tuesday, March 27 \| 8:00AM - 11:15AM Retroviral Entry Mechanisms (Joint) Room: Sea to Sky B/C Speaker 7 of 7 Kelechi C. Chikere, University of California, Los Angeles, USA Short Talk: High Throughput Receptor Affinity Profiling Reveals Distinct Entry Efficiency Patterns amongst HIV-1 Isolates that Correlate with Pathogenic and Biological Phenotypes
Tuesday, March 27 \| 9:20AM - 9:40AM Coffee Break Room: Grand Foyer
Tuesday, March 27 \| 11:15AM - 1:00PM Poster Setup Room: Sea to Sky A
Tuesday, March 27 \| 11:15AM - 11:15AM On Own for Lunch and Recreation
Tuesday, March 27 \| 1:00PM - 10:00PM Poster Viewing Room: Sea to Sky A
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 1 of 9 * Benhur Lee, University of California, Los Angeles, USA
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 2 of 9 Aaron J. Arvey, Gilead, USA Profiling the Genome-Wide Regulatory Network of a Tumor Virus and Its Human Host
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 3 of 9 Benjamin K. Chen, Mount Sinai School of Medicine, USA Coupled HIV-1 Endocytosis and Maturation-Induced Viral Fusion during Cell-Cell Infection
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 4 of 9 Daniel C. DiMaio, Yale University School of Medicine, USA Artificial Transmembrane Proteins that Inhibit CCR5 Expression and HIV Co-Receptor Activity
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 5 of 9 J. Nicholas Francis, University of Utah, USA Membrane Localization of D-Peptide HIV Entry Inhibitors
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 6 of 9 Tijana Ivanovic, Harvard Medical School, USA Dissecting Conformational Rearrangements in Influenza-Virus Hemagglutinin through a Single-Virion Membrane-Fusion Assay
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 7 of 9 Jason Kindrachuk, National Institutes of Health, USA Temporal Systems Kinomics Analysis of Host Cell Responses to Ebola
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 8 of 9 Emma-Kate Loveday, University of British Columbia, Canada Temporal and Strain-Specific Host MicroRNA Molecular Signatures Associated with Swine-Origin H1N1 and Avian-Origin H7N7 Influenza A Virus Infection
Tuesday, March 27 \| 2:30PM - 4:30PM Workshop 1: New Approaches to the Study of Treatment of Vira l Infections Room: Sea to Sky C Speaker 9 of 9 Jason A. Wojcechowskyj, University of Pennsylvania, USA How HIV Reprograms Cells - Quantitative Phosphoproteomics during HIV Entry
Tuesday, March 27 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Tuesday, March 27 \| 5:00PM - 7:00PM Inhibition of Virus Entry (Joint) Room: Sea to Sky B/C Speaker 1 of 5 * Amy Jacobs, State University of New York at Buffalo, USA
Tuesday, March 27 \| 5:00PM - 7:00PM Inhibition of Virus Entry (Joint) Room: Sea to Sky B/C Speaker 2 of 5 Peter D. Kwong, NIAID, National Institutes of Health, USA Effective Antibody-Mediated Inhibition of HIV-1 Entry
Tuesday, March 27 \| 5:00PM - 7:00PM Inhibition of Virus Entry (Joint) Room: Sea to Sky B/C Speaker 3 of 5 Peter S. Kim, Stanford University, USA Vaccine Candidates that Mimic the HIV-1 gp41 Pre-Hairpin Intermediate
Tuesday, March 27 \| 5:00PM - 7:00PM Inhibition of Virus Entry (Joint) Room: Sea to Sky B/C Speaker 4 of 5 Michael Farzan, The Scripps Research Institute, USA The Sulfotyrosine-Binding Pockets of gp120 as a Therapeutic Target
Tuesday, March 27 \| 5:00PM - 7:00PM Inhibition of Virus Entry (Joint) Room: Sea to Sky B/C Speaker 5 of 5 Jie Xue, Stanford University, USA Short Talk: Biochemical Investigation of the Mechanism of Griffithsin: Dimer Structure Plays an Essential Role in Griffithsin Function
Tuesday, March 27 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Tuesday, March 27 \| 7:30PM - 10:00PM Poster Session 1 Room: Sea to Sky A
Wednesday, March 28 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A, Garibaldi B/C
Wednesday, March 28 \| 8:00AM - 11:00AM Anti-Viral Therapeutics: New and Old Paradigms Room: Sea to Sky C Speaker 1 of 5 * Kartik Chandran, Albert Einstein College of Medicine, USA
Wednesday, March 28 \| 8:00AM - 11:00AM Anti-Viral Therapeutics: New and Old Paradigms Room: Sea to Sky C Speaker 2 of 5 Benhur Lee, University of California, Los Angeles, USA Mechanistic Basis of Broad Spectrum Antivirals that Target Virus-Cell Fusion
Wednesday, March 28 \| 8:00AM - 11:00AM Anti-Viral Therapeutics: New and Old Paradigms Room: Sea to Sky C Speaker 3 of 5 Benjamin R. TenOever, Icahn School of Medicine at Mount Sinai, USA miRNA-Mediated Control of Virus Infection
Wednesday, March 28 \| 8:00AM - 11:00AM Anti-Viral Therapeutics: New and Old Paradigms Room: Sea to Sky C Speaker 4 of 5 JoAnn A. Suzich, AstraZeneca, USA Treating Respiratory Syncytial Virus Infections
Wednesday, March 28 \| 8:00AM - 11:00AM Anti-Viral Therapeutics: New and Old Paradigms Room: Sea to Sky C Speaker 5 of 5 Phoebe L. Stewart, Case Western Reserve University, USA Defensin Neutralization of Adenovirus
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 7 * David M. Margolis, University of North Carolina at Chapel Hill, USA
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 7 Eric M. Verdin, Buck Institute for Research on Aging, USA Roles of Proviral Integration Sites
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 7 Melanie M. Ott, Gladstone Institutes, USA Regulation of HIV-1 Transcription by Tat Posttranslational Modifications
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 7 Matthew J. Pace, University of Oxford, UK Short Talk: Direct Infection of Resting CD4+ T Cells with HIV Leads to Not Only Integration but also Expression of Gag Proteins without Efficient Viral Spread in a Model of HIV Latency
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 7 Jonathan Karn, Case Western Reserve University, USA Control of HIV Latency by Epigenetic and Non-Epigenetic Silencing
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 6 of 7 Mario Stevenson, University of Miami, Leonard M. Miller School of Medicine, USA Tissue Analysis of Viral Reservoirs in Patients on ART
Wednesday, March 28 \| 8:00AM - 11:15AM Mechanisms of HIV Latency This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 7 of 7 Sharon Schlesinger, Columbia University, College of Physicians and Surgeons, USA Short Talk: Proviral Silencing in Embryonic Cells: Why YY1?
Wednesday, March 28 \| 9:20AM - 9:40AM Coffee Break Room: Grand Foyer
Wednesday, March 28 \| 11:00AM - 1:00PM Poster Setup Room: Sea to Sky A
Wednesday, March 28 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Wednesday, March 28 \| 1:00PM - 10:00PM Poster Viewing Room: Sea to Sky A
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 7 * Andrew J. Henderson, Boston University School of Medicine, USA
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 7 Ramesh K. Akkina, Colorado State University, USA Topical Gel Formulation of Broadly Neutralizing Anti-HIV-1 Monoclonal Antibody VRC01 Protects against HIV-1 Vaginal Challenge in a Humanized Mouse Model
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 7 Li Liu, NIAID, National Institutes of Health, USA Neutralization Epitope Masking within the Native HIV-1 Env Trimer: Intraprotomer Rather than Interprotomer Masking of V3 Epitopes by V1V2
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 7 Eugenio Montini, Fondazione Telethon, Italy Assessing the Impact of Lentiviral Vector Integration on Splicing of Cellular Genes at the Genome-Wide Level
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 7 Webster L. Santos, Virginia Tech, USA Inhibiting RNA-Protein Interactions: Cell Permeable Branched Peptide Boronic Acids Inhibit Tat-TAR and Rev-RRE Interactions
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 6 of 7 Kayoko Waki, NCI, National Institutes of Health, USA A Tale of Two HIV-1 Maturation Inhibitors – Bevirimat (BVM) and PF-46396: Insights into Gag Assembly and Virion Maturation
Wednesday, March 28 \| 2:30PM - 4:30PM Workshop 1: New Pharmacologies/Intervention This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 7 of 7 Keith R. Jerome, Fred Hutchinson Cancer Research Center, USA Pharmacodynamic Considerations in Targeted Endonuclease Therapy for HIV
Wednesday, March 28 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Wednesday, March 28 \| 5:00PM - 7:00PM Viral Entry Processes Room: Sea to Sky C Speaker 1 of 5 * Sean P. Whelan, Harvard Medical School, USA
Wednesday, March 28 \| 5:00PM - 7:00PM Viral Entry Processes Room: Sea to Sky C Speaker 2 of 5 Judith M. White, University of Virginia Health Sciences Center, USA Roles for Cathepsin Priming of the Ebola Virus Glycoprotein for Cellular Entry
Wednesday, March 28 \| 5:00PM - 7:00PM Viral Entry Processes Room: Sea to Sky C Speaker 3 of 5 Lucas Pelkmans, University of Zürich, Switzerland Cell-to-Cell Variability Modeling of Virus Infection Reveals Complex Population-Determined RNAi Phenotypes
Wednesday, March 28 \| 5:00PM - 7:00PM Viral Entry Processes Room: Sea to Sky C Speaker 4 of 5 Roselyn J. Eisenberg, University of Pennsylvania, USA Herpes Virus Fusion and Entry: A Story with Many Characters
Wednesday, March 28 \| 5:00PM - 7:00PM Viral Entry Processes Room: Sea to Sky C Speaker 5 of 5 Mathieu Mateo, Mayo Clinic, USA Short Talk: Nectin-4 is the Measles Virus Host Exit Receptor
Wednesday, March 28 \| 5:00PM - 7:00PM HIV Therapy: State of the Art This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 5 * Celia A. Schiffer, University of Massachusetts Medical School, USA
Wednesday, March 28 \| 5:00PM - 7:00PM HIV Therapy: State of the Art This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 5 Douglas D. Richman, University of California, San Diego, USA Measuring the Latent Reservoir
Wednesday, March 28 \| 5:00PM - 7:00PM HIV Therapy: State of the Art This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 5 Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA TCR Clonotypes Modulate the Protective Effect of HLA Class I Alleles in HIV-1 Infection
Wednesday, March 28 \| 5:00PM - 7:00PM HIV Therapy: State of the Art This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 5 Tae-Wook Chun, NIAID, National Institutes of Health, USA Cellular Reservoirs of HIV: Perspectives for Eradication and Development of Therapeutic Strategies
Wednesday, March 28 \| 5:00PM - 7:00PM HIV Therapy: State of the Art This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 5 Mathias Lichterfeld, Brigham and Women's Hospital, USA Short Talk: Treatment of Early HIV-1 Infection Reduces Viral Reservoirs in CD4 T Cells to Levels Found in Elite Controllers
Wednesday, March 28 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Wednesday, March 28 \| 7:30PM - 10:00PM Poster Session 2 Room: Sea to Sky A
Thursday, March 29 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A, Garibaldi B/C
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 1 of 7 * Stephen C. Harrison, Harvard Medical School, USA
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 2 of 7 Z. Hong Zhou, University of California, Los Angeles, USA Atomic Structures by cryoEM Suggest Divergent Mechanisms of Entry by dsRNA Viruses
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 3 of 7 Glen R. Nemerow, The Scripps Research Institute, USA Adenovirus Structure
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 4 of 7 Félix Rey, Institut Pasteur, France The First Snapshot of a Cell-Cell Fusion Protein Reveals Unanticipated Links with Viruses
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 5 of 7 Timothy F. Booth, Public Health Agency of Canada, Canada Short Talk: Three-Dimensional Structure of Ebola Virus Determined by Cryo-Electron Microscopy and Cryo-Electron Tomography
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 6 of 7 Kai Xu, National Institutes of Health, USA Short Talk: Crystal Structure of the Nipah Virus Fusion Glycoprotein Reveals a Functionally Essential Hexameric Assembly
Thursday, March 29 \| 8:00AM - 11:00AM Structural Approaches to Virology Room: Sea to Sky C Speaker 7 of 7 Robin Löving, Karolinska Institutet, Sweden Short Talk: Maturation Cleavage of the Retrovirus Mo-MLV Spike Precursor Splays the Transmembrane Subunits to Prime it for Receptor Triggering
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 7 * Carol D. Weiss, US Food and Drug Administration, USA
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 7 David M. Margolis, University of North Carolina at Chapel Hill, USA Targeting Latency for Eradication: State of the Art
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 7 Daria J. Hazuda, Merck Research Laboratories, USA The HIV-1 Eradication Pipeline: Challenges and Opportunities
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 7 Jan Chemnitz, Heinrich Pette Institute, Germany Short Talk: Excision of Proviral DNA by Tre-Recombinase in HIV-Infected Humanized Mice
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 7 John W. Mellors, University of Pittsburgh School of Medicine, USA Clinical Trials of Strategies to Cure HIV-1 Infection
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 6 of 7 Sharon R. Lewin, University of Melbourne, Australia Understanding Infection of Resting T-Cells and Maintenance of Latency: The Role of Myeloid Dendritic Cells
Thursday, March 29 \| 8:00AM - 11:15AM Targeting Latency for Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 7 of 7 Kathryn Miller-Jensen, Yale University, USA Short Talk: Chromatin Accessibility at the HIV-1 LTR Promoter Sets a Threshold for NF-kappaB-Mediated Viral Gene Expression
Thursday, March 29 \| 9:20AM - 9:40AM Coffee Break Room: Grand Foyer
Thursday, March 29 \| 11:00AM - 1:00PM Poster Setup Room: Sea to Sky A
Thursday, March 29 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Thursday, March 29 \| 1:00PM - 10:00PM Poster Viewing Room: Sea to Sky A
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 1 of 7 * Judith M. White, University of Virginia Health Sciences Center, USA
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 2 of 7 Susanna Ruth Bidgood, MRC Laboratory of Molecular Biology, UK Mechanism of Antibody-Dependent Intracellular Neutralization Mediated by TRIM21
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 3 of 7 Chengyu Liang, University of Southern California, USA Autophagic Tumor Suppressor UVRAG Controls Viral Endosomal Transport and Release
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 4 of 7 Emily Happy Miller, Albert Einstein College of Medicine, USA Host-Programmed Recognition of an Intracellular Entry Receptor by Ebola Virus
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 5 of 7 Frank Neipel, Universitaet Erlangen, Germany The Ephrin Receptor Tyrosine Kinase A2 is a Cellular Receptor for Kaposi’s Sarcoma-Associated Herpesvirus
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 6 of 7 Ryan S. Noyce, Dalhousie University, Canada Tumor Cell Marker PVRL4 (NECTIN 4) is an Epithelial Cell Receptor for Measles Virus
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Virus Host Interactions Room: Sea to Sky C Speaker 7 of 7 Christopher M. Robinson, Indiana University, USA Virus-Microbiota Interactions in the Gut: The Role of Bacterial Polysaccharides
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 9 * Thomas J. Hope, Northwestern University, USA
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 9 Lars-Anders Carlson, NIDDK, National Institutes of Health, USA Towards an in vitro Reconstitution of HIV-1 Assembly and Release
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 9 Tonya Kueck, King's College London, UK A Trafficking Determinant in HIV-1 VPU is Essential to Counteract Type 1 Interferon-Induced Levels of Tetherin in CD4+ T Cells
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 9 Kyeongeun Lee, NCI, National Institutes of Health, USA CPSF6 and TNPO3 Interactions Regulate HIV-1 Infection
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 9 Quentin J. Sattentau, Sir William Dunn School of Pathology, UK Efficient Macrophage Infection by Uptake of Dying HIV-1-Infected T Cells
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 6 of 9 Nicholas Francella, University of Pennsylvania, USA Emergence of CD4-Independent SIV Variants during in vivo SIV Adaptation to a Lack of CD4
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 7 of 9 Anna Christina Kajaste-Rudnitski, San Raffaele Scientific Institute, Italy Molecular Insights Into TRIM22-Mediated HIV-1 Transcriptional Repression
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 8 of 9 Felipe DiazGriffero, Einstein, USA RING Domain Mutations Uncouple TRIM5alpha Restriction of HIV-1 from Inhibition of Reverse Transcription and Acceleration of Uncoating
Thursday, March 29 \| 2:30PM - 4:30PM Workshop 2: Cell Biology of HIV Infection This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 9 of 9 Angela M. Gronenborn, University of Pittsburgh, USA Structures of Vpr and Vpx in DDB1-DCAF1 Complexes - Unique Surfaces for Substrate Recruitment
Thursday, March 29 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Thursday, March 29 \| 5:00PM - 7:00PM Systems Approaches to Virology Room: Sea to Sky C Speaker 1 of 5 * Nir Hacohen, Massachusetts General Hospital, USA
Thursday, March 29 \| 5:00PM - 7:00PM Systems Approaches to Virology Room: Sea to Sky C Speaker 2 of 5 Andrew Fire, Stanford University, USA Evolution of Effector Repertoire in Response to Viral Infection
Thursday, March 29 \| 5:00PM - 7:00PM Systems Approaches to Virology Room: Sea to Sky C Speaker 3 of 5 Abraham L. Brass, University of Massachusetts Medical School, USA Genetic Strategies to Investigate Host-Virus Interactions
Thursday, March 29 \| 5:00PM - 7:00PM Systems Approaches to Virology Room: Sea to Sky C Speaker 4 of 5 Bruce M. McManus, University of British Columbia, Canada Host Signaling Response to Coxsackievirus B3
Thursday, March 29 \| 5:00PM - 7:00PM Systems Approaches to Virology Room: Sea to Sky C Speaker 5 of 5 Gilad Sivan, NIAID, National Institutes of Health, USA Short Talk: Human Genome-Wide siRNA Screen Reveals the Importance of the Nuclear Pores for the Cytoplasmic Life Cycle of Vaccinia Virus
Thursday, March 29 \| 5:00PM - 7:00PM New Approaches to Antiviral Treatment This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 5 * Douglas D. Richman, University of California, San Diego, USA
Thursday, March 29 \| 5:00PM - 7:00PM New Approaches to Antiviral Treatment This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 5 Zeger Debyser, KU Leuven, Belgium LEDGINs Potently Inhibit HIV Replication and Block Multiple Functions during Integration
Thursday, March 29 \| 5:00PM - 7:00PM New Approaches to Antiviral Treatment This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 5 Paula M. Cannon, University of Southern California, Keck School of Medicine, USA Engineering Cells to Resist HIV Infection by CCR5 Knockout
Thursday, March 29 \| 5:00PM - 7:00PM New Approaches to Antiviral Treatment This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 5 Sarah E. Palmer, University of Sydney, Australia Characterizing and Targeting Latent HIV Reservoirs
Thursday, March 29 \| 5:00PM - 7:00PM New Approaches to Antiviral Treatment This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 5 Patrick M. Younan, Fred Hutchinson Cancer Research Center, USA Short Talk: Immune Response Promotes Recovery of Unmodified CD4+ T-Cells in the SHIV-Macaque Model after Hematopoietic Stem Cell Gene Therapy
Thursday, March 29 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Thursday, March 29 \| 7:30PM - 10:00PM Poster Session 3 Room: Sea to Sky A
Friday, March 30 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A, Garibaldi B/C
Friday, March 30 \| 8:00AM - 11:00AM Immunity and Viral Evasion Room: Sea to Sky C Speaker 1 of 5 * Michael Farzan, The Scripps Research Institute, USA
Friday, March 30 \| 8:00AM - 11:00AM Immunity and Viral Evasion Room: Sea to Sky C Speaker 2 of 5 Dan R. Littman, HHMI/New York University School of Medicine, USA Dendritic Cell Sensing
Friday, March 30 \| 8:00AM - 11:00AM Immunity and Viral Evasion Room: Sea to Sky C Speaker 3 of 5 Jonathan C. Kagan, Boston Children's Hospital, USA Peroxisomes, MAVS and Innate Immunity
Friday, March 30 \| 8:00AM - 11:00AM Immunity and Viral Evasion Room: Sea to Sky C Speaker 4 of 5 Diane E. Griffin, Johns Hopkins Bloomberg School of Public Health, USA Measles: Determinants of Virus Clearance and Protective Immunity
Friday, March 30 \| 8:00AM - 11:00AM Immunity and Viral Evasion Room: Sea to Sky C Speaker 5 of 5 Nir Hacohen, Massachusetts General Hospital, USA Innate Responses to Influenza A Virus
Friday, March 30 \| 8:00AM - 11:00AM Models for Therapy and Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 6 * Melanie M. Ott, Gladstone Institutes, USA
Friday, March 30 \| 8:00AM - 11:00AM Models for Therapy and Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 6 J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill, USA The Humanized BLT Mouse Model
Friday, March 30 \| 8:00AM - 11:00AM Models for Therapy and Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 6 Zandrea Ambrose, University of Pittsburgh, USA Using Macaque Models to Study HIV Persistence and Eradication Strategies
Friday, March 30 \| 8:00AM - 11:00AM Models for Therapy and Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 6 Binhua Ling, Tulane National Primate Research Center, USA Short Talk: The Effect of Antiretroviral Therapy on SIV Gut Mucosal Reservoirs in Chinese Rhesus macaques of SIV Infection – New Non-Human Primate Model for Identification and Eradication of HIV Tissue Reservoirs
Friday, March 30 \| 8:00AM - 11:00AM Models for Therapy and Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 6 Kathleen L. Collins, University of Michigan Medical Center, USA HIV-1 Infection of Hematopoietic Progenitor Cells
Friday, March 30 \| 8:00AM - 11:00AM Models for Therapy and Eradication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 6 of 6 Jeffrey D. Lifson, Leidos Biomedical Research, Inc., USA Short Talk: Strategies for Evaluation of Residual Virus and Viral Eradication Approaches in Antiretroviral Drug Suppressed, SIV-Infected Rhesus macaques
Friday, March 30 \| 9:20AM - 9:40AM Coffee Break Room: Grand Foyer
Friday, March 30 \| 11:00AM - 1:00PM Poster Setup Room: Sea to Sky A
Friday, March 30 \| 11:00AM - 11:00AM On Own for Lunch and Recreation
Friday, March 30 \| 1:00PM - 10:00PM Poster Viewing Room: Sea to Sky A
Friday, March 30 \| 4:30PM - 5:00PM Coffee Available Room: Grand Foyer
Friday, March 30 \| 5:00PM - 7:00PM Viral Assembly and Replication Room: Sea to Sky C Speaker 1 of 6 * Andrew Mehle, University of Wisconsin, Madison, USA
Friday, March 30 \| 5:00PM - 7:00PM Viral Assembly and Replication Room: Sea to Sky C Speaker 2 of 6 Sean P. Whelan, Harvard Medical School, USA Control of Polymerase Activity during Replication and Assembly of Negative-Sense RNA Viruses
Friday, March 30 \| 5:00PM - 7:00PM Viral Assembly and Replication Room: Sea to Sky C Speaker 3 of 6 Barbara Müller, Heidelberg University Hospital, Germany HIV Assembly and Maturation
Friday, March 30 \| 5:00PM - 7:00PM Viral Assembly and Replication Room: Sea to Sky C Speaker 4 of 6 Emily Bruce, University of Cambridge, UK Short Talk: Rab11 and its Effector Myosin Vb are Involved in Late Stages of Influenza Virus Assembly and Budding
Friday, March 30 \| 5:00PM - 7:00PM Viral Assembly and Replication Room: Sea to Sky C Speaker 5 of 6 Mickey J. Pentecost, David Geffen School of Medicine at University of California, Los Angeles, USA Short Talk: SUMO and Ubiquitin Modifications in the Subnuclear Trafficking and Function of Nipah Virus Matrix
Friday, March 30 \| 5:00PM - 7:00PM Viral Assembly and Replication Room: Sea to Sky C Speaker 6 of 6 Roland Schwarzer, Humboldt University, Germany Short Talk: The Role of Lipid Rafts in Virus Assembly
Friday, March 30 \| 5:00PM - 7:00PM Host Factors and HIV Replication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 1 of 5 * Angela M. Gronenborn, University of Pittsburgh, USA
Friday, March 30 \| 5:00PM - 7:00PM Host Factors and HIV Replication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 2 of 5 Alan N. Engelman, Dana-Farber Cancer Institute, USA HIV-Host Interactions in Nuclear Import and Integration
Friday, March 30 \| 5:00PM - 7:00PM Host Factors and HIV Replication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 3 of 5 Eric O. Freed, NCI, National Institutes of Health, USA Host Cell Factors in Retrovirus Assembly and Release
Friday, March 30 \| 5:00PM - 7:00PM Host Factors and HIV Replication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 4 of 5 Jonathan P. Stoye, Francis Crick Institute, UK SAMHD1 and HIV-1 Replication
Friday, March 30 \| 5:00PM - 7:00PM Host Factors and HIV Replication This session is from HIV Pathogenesis Room: Sea to Sky B Speaker 5 of 5 Schuyler Van Engelenburg, NICHD, National Institutes of Health, USA Short Talk: Characterization of HIV-1 Gag Assembly and Particle Production
Friday, March 30 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Friday, March 30 \| 8:00PM - 11:00PM Entertainment Room: Sea to Sky A
Friday, March 30 \| 8:00PM - 11:00PM Cash Bar Room: Sea to Sky A
Saturday, March 31 \| 10:23AM - 10:23AM Departure *Session Chair †Invited, not yet responded.