Web Desc
Understanding Dendritic Cell Biology to Advance Disease Therapies
Organizer(s): Miriam Merad and Bart N. Lambrecht
Date: March 03 - 08, 2013
Location: Keystone Resort, Keystone, CO, USA
Supported by the Directors' Fund
For important information on the coronavirus, please click here
Summary of Meeting:
Tissue macrophages and dendritic cells (DC) are tissue hematopoietic cells that share the ability to sample the environment but have distinct function in tissue immunity. Controversies remain on the best way to distinguish macrophages from DC in vivo. Results in recent months have established that DC derive from a specific hematopoietic lineage in the bone marrow controlled by a unique molecular program distinct from other myeloid programs. Recent results have also established that DC are heterogeneous in origin and function and that dysregulated biology of DC subsets contribute to the pathogenesis of immune disease. The main goal of this Keystone Symposia meeting is to review recent developments in our understanding of basic DC biology and to discuss the relevance of these findings to the pathogenesis of human immune disease. Specifically, we will discuss the mechanisms that control DC differentiation in lymphoid and non-lymphoid tissues during the steady state and diseased state, both at the cellular and transcriptional levels. We will discuss recent developments in our understanding of the molecular control of three unique DC functions that include migration to of the lymph nodes, presentation antigens, and polarization of T cell immune responses. We will debate the role of DC in immune disease – including auto-immunity, inflammation and allergic disease – and address the recent controversy on the role of DC versus basophils in the induction of Th2 response. Specifically, we will discuss the recent discovery of the molecular signature of Langerhans cell histiocytosis, a poorly understood disease that results from the accumulation/proliferation of langerin+ DC. Finally, we will review the relevance of DC in therapy and the basic mechanisms of action of the cell vaccine “Provenge” that has recently been approved by the FDA for the treatment of prostate cancer. The Keystone Symposia meeting on Understanding Dendritic Cell Biology to Improve Human Disease will bring together physicians experts in autoimmune disease, allergy and cancer, immunologists, geneticists, cancer biologists and vaccinologists. We will also invite scientists from the pharmaceutical industry as well as Journal Editors to maximize the interactions between different members of our community and thereby improve our understanding of the key role that DC play in the modulation of human disease and in medicine.
Scholarship Deadline: November 6 2012
Discounted Abstract Deadline: November 6 2012
Abstract Deadline: December 3 2012
Discounted Registration Deadline: December 20 2012
Abstacts when book is in proofing process


We gratefully acknowledge additional support for this conference from:
Chroma Technology Corporation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.

Tokyo Medical and Dental University
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI104118-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 03 | 4:00PM - 8:00PM
Arrival and Registration
Room: Keystone Lodge Foyer


Monday, March 04 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Monday, March 04 | 8:00AM - 9:00AM
Welcome and Keynote Address

Speaker 1 of 3
Miriam Merad, Mount Sinai School of Medicine, USA
Welcome Remarks

Monday, March 04 | 8:00AM - 9:00AM
Welcome and Keynote Address

Speaker 2 of 3
* Bart N. Lambrecht, VIB, Ghent University, Belgium

Monday, March 04 | 8:00AM - 9:00AM
Welcome and Keynote Address

Speaker 3 of 3
Michel C. Nussenzweig, HHMI/Rockefeller University, USA
Ralph Steinman and the Dendritic Cell Discovery

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 1 of 6
* Miriam Merad, Mount Sinai School of Medicine, USA
Nature versus Nurture Control of the Dendritic Cells Lineage

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 2 of 6
Boris Reizis, New York University Langone Medical Center, USA
Regulation of Plasmacytoid Dendritic Cell Development and Function

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 3 of 6
Bernard Malissen, Centre d'Immunologie de Marseille-Luminy, France
Fine-Grained Analysis of the Macrophages and Dendritic Cells Present in the Mouse Skin

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 4 of 6
* Kenneth M. Murphy, HHMI/Washington University School of Medicine, USA
Transcriptional Control of DC Development

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 5 of 6
Florent Ginhoux, Singapore Immunology Network, Singapore
Short Talk: Revisiting the Ontogeny of the Mononuclear Phagocyte System: Embryonic and Adult Hematopoietic Contributions

Monday, March 04 | 9:00AM - 12:15PM
Development of Tissue-Resident and Inflammatory DC
Room: Grays Peak

Speaker 6 of 6
Richard A. Kroczek, Robert Koch-Institute, Germany
Short Talk: The Chemokine Receptor XCR1 Is a Lineage Marker for Cross-Presenting DCs

Monday, March 04 | 9:40AM - 10:00AM
Coffee Break
Room: Longs Peak Foyer


Monday, March 04 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Monday, March 04 | 12:15PM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Monday, March 04 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 1 of 10
* Bernard Malissen, Centre d'Immunologie de Marseille-Luminy, France

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 2 of 10
* Nir Hacohen, Massachusetts General Hospital, USA

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 3 of 10
Venetia Bigley, Newcastle University, UK
Dendritic Cells in Human Primary Immunodeficiencies: Insights into DC Biology

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 4 of 10
Herbert Strobl, Medical University Graz, Austria
Identification of the Receptor Tyrosine Kinase Axl as a Downstream Effector of TGF-beta1 during Langerhans Cell Differentiation and Epidermal Homeostasis

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 5 of 10
Romain F. Banchereau, Baylor Institute for Immunology Research, USA
A Modular Transcriptional Framework Characterizes Human Dendritic Cell Responses to Pathogens and Vaccines

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 6 of 10
Gaëlle Breton, Rockefeller University, USA
Gene Profiling of Dendritic Cell Subsets after in vivo Administration of TLR3 Agonist in Healthy Human Volunteers

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 7 of 10
Charlotte L. Scott, University of Ghent & VIB, Belgium
Conventional Dendritic Cell Precursors Give Rise to Four Distinct Subsets of Dendritic Cells in the Steady State Intestine

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 8 of 10
Laura Gutiérrez, Sanquin Research and Landsteiner Laboratory, Netherlands
What Does Gata1 Do to Dendritic Cells?

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 9 of 10
Alan D. Guerrero, NIDDK, National Institutes of Health, USA
IL-2 Inhibits Dendritic Cell Development by Acting on Precursors and Altering DC-Associated Transcription Factors

Monday, March 04 | 2:30PM - 4:30PM
Workshop 1: Transcriptional Control of DC Development and Fu
nction
Room: Grays Peak

Speaker 10 of 10
Evangelos Andreakos, Biomedical Research Foundation-Academy of Athens, Greece
IL-28A (IFN-lambda2) Modulates Lung DC Function to Promote Th1 Immune Skewing and Suppress Allergic Airway Disease

Monday, March 04 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 1 of 4
Hideki Ueno, Icahn School of Medicine at Mount Sinai, USA
Functional Specialization of Human DC Subsets

Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 2 of 4
Nir Hacohen, Massachusetts General Hospital, USA
Genes and Networks Underlying Dendritic Cell Activation

Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 3 of 4
* Bali Pulendran, Stanford University School of Medicine, USA
Systems Vaccinology: Enabling Rational Vaccine Design with Systems Biology

Monday, March 04 | 5:00PM - 7:00PM
Transcriptional Control of DC Development and Function
Room: Grays Peak

Speaker 4 of 4
Shalin H. Naik, Walter & Eliza Hall Institute, Australia
Short Talk: Single Hematopoietic Progenitor Tracing Reveals Dendritic Cells Are a Distinct Lineage

Monday, March 04 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Monday, March 04 | 7:30PM - 10:00PM
Poster Session 1
Room: Shavano/Torreys


Tuesday, March 05 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 1 of 7
* Bart N. Lambrecht, VIB, Ghent University, Belgium
Dendritic Cells and the Unfolded Protein Response

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 2 of 7
* Averil I. Ma, University of California, San Francisco, USA
Ubiquitination and DC Functions

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 3 of 7
Davor Frleta, Mt. Sinai Medical Center, USA
Short Talk: HIV-1 Infection-Induced Apoptotic Microparticles Inhibit Human Dendritic Cells via CD44

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 4 of 7
Pablo Vargas, Institut Curie, France
Short Talk: Developmental Regulation of Dendritic Cell Migration

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 5 of 7
Lesley Ann Smyth, King's College London, UK
Short Talk: Intercellular Transfer of Regulatory T Cell Specific MicroRNA to Dendritic Cells Leads to Modulation of Dendritic Cell Function

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 6 of 7
Diana Matheoud, Université de Montréal, Canada
Short Talk: Leishmania Inhibits Crosspresentation through the Cleavage of VAMP8

Tuesday, March 05 | 8:00AM - 11:00AM
Cell Biology and Antigen Processing
Room: Grays Peak

Speaker 7 of 7
Marianne L. Boes, University Medical Centre, Netherlands
Short Talk: Potentiation of Cross-Presentation by Human Blood and Lymphoid Tissue BDCA-3+ Dendritic Cells

Tuesday, March 05 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 05 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Tuesday, March 05 | 11:00AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Tuesday, March 05 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 1 of 10
* Nicolas Manel, Institut Curie, France

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 2 of 10
* Peter T. Lee, Immunity, Cell Press, USA

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 3 of 10
Yasuyuki Saito, Kobe University Graduate School of Medicine, Japan
Dendritic Cell Homeostasis Is Maintained by Non-Hematopoietic and T Cell-Produced Flt3-Ligand in Steady-State and during Antigen-Specific Immune Responses

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 4 of 10
Sonja I. Buschow, Nijmegen Centre for Molecular Life Sciences, Netherlands
The Human Dendritic Cell Phagosome Proteome: Novel Players and Implications for the Regulation of Receptor Mediation Phagocytosis

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 5 of 10
Cary D. Austin, Genentech, Inc., USA
Mice with Conditional Deletion of NF-kappaB–Inducing Kinase (NIK) in Dendritic Cells Show Defective CD40-Dependent Antigen Cross-Priming of CD8+ T Cells

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 6 of 10
Jeoung-Sook Shin, University of California, San Francisco, USA
Ubiquitin-Mediated MHCII Turnover Promotes Dendritic Cell Selection of Natural Regulatory T Cells

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 7 of 10
Zhe Wang, Purdue University, USA
Critical Role of Linear Ubiquitin Regulator SHARPIN in NF-kappaB Signaling and Induction of TH1 Cells by Dendritic Cells

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 8 of 10
Ilaria Tassi, Alector, USA
The NF-kappaB Regulator Bcl-3 Plays a Critical Role in the Initiation of Adaptive Immune Responses

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 9 of 10
Mitsuo Hashimoto, University of California, San Francisco, USA
The Role of alphanubeta8-Mediated Activation of TGF-beta by Fibroblasts in Directing Dendritic Cell Migration

Tuesday, March 05 | 2:30PM - 4:30PM
Workshop 2: Regulation of DC Function
Room: Grays Peak

Speaker 10 of 10
Guy Shakhar, Weizmann Institute of Science, Israel
Dynamic Imaging Reveals Promiscuous Cross-Presentation of Blood-Borne Antigens to Naïve CD8+ T Cells in the Bone Marrow

Tuesday, March 05 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 1 of 4
* Gwendalyn J. Randolph, Washington University, USA
Normal Dendritic Cell Mobilization to Lymph Nodes under Conditions of Severe Lymphatic Hypoplasia

Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 2 of 4
Reinhold Förster, Hannover Medical School, Germany
Lymph Node Homing of DCs, pDCs, and Activated T Cells via Afferent Lymphatics

Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 3 of 4
Michael Sixt, Institute of Science and Technology Austria, Austria
Cytoskeletal Dynamics of Dendritic Cells

Tuesday, March 05 | 5:00PM - 7:00PM
Molecular and Functional Aspects of DC Migration
Room: Grays Peak

Speaker 4 of 4
Stephanie C. Eisenbarth, Yale University, USA
Short Talk: NOD-Like Receptor NLRP10 Regulates Migration of CD11b-Positive Dendritic Cells

Tuesday, March 05 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Tuesday, March 05 | 7:30PM - 10:00PM
Poster Session 2
Room: Shavano/Torreys


Wednesday, March 06 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 1 of 5
Eicke Latz, University of Bonn, Germany
Inflammasome Activation in Macrophages and Dendritic Cells

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 2 of 5
* Laurence Zitvogel, Institut Gustave Roussy, France
Gut Microbiota Influences T Cell-Dependent Anticancer Immunity during Chemotherapy

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 3 of 5
Romina S. Goldszmid, NCI, National Institutes of Health, USA
Short Talk: Commensal Microbiota Modulates the Innate Response to Cancer Immunotherapy and Chemotherapy

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 4 of 5
* Yong-Jun Liu, Sanofi, USA
Biochemical Characterization of Nucleic Acid Sensors in Dendritic Cells

Wednesday, March 06 | 8:00AM - 11:15AM
DC Sensing of the Environment
Room: Grays Peak

Speaker 5 of 5
Nicolas Manel, Institut Curie, France
Short Talk: HIV Capsid Dissociates Cytosolic Sensing and Productive Infection in Dendritic Cells

Wednesday, March 06 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, March 06 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Wednesday, March 06 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Wednesday, March 06 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Wednesday, March 06 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 1 of 4
Brian D. Brown, Mount Sinai School of Medicine, USA
MicroRNA Control of DC Development

Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 2 of 4
* Marco Colonna, Washington University School of Medicine, USA
pDC in Host Defense

Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 3 of 4
Toshiaki Ohteki, Tokyo Medical and Dental University, Japan
New DC Progenitors with Prominent pDC Differentiation Potential

Wednesday, March 06 | 5:00PM - 7:00PM
Role of PDC in Immunity and Disease
Room: Grays Peak

Speaker 4 of 4
Miguel A. Sanjuan, Bristol-Myers Squibb Co., USA
Short Talk: LC3-Associated Phagocytosis Mediates IFN-alpha Secretion in Response to DNA-Immune Complexes

Wednesday, March 06 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Wednesday, March 06 | 7:30PM - 10:00PM
Poster Session 3
Room: Shavano/Torreys


Thursday, March 07 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 1 of 6
Matthew L. Albert, Genentech, Inc., USA
Influence of Cell Death on Tumor Immunity

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 2 of 6
* William R. Heath, University of Melbourne, Australia
Dendritic Cells, Receptors and Initiation of Immunity

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 3 of 6
* Steffen Jung, Weizmann Institute of Science, Israel
Critical Dendritic Cell / Macrophage Crosstalk in the Intestinal Lamina Propria

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 4 of 6
Hamida Hammad, Ghent University & VIB, Belgium
Role of Dendritic Cells in the Pathogenesis of Asthma

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 5 of 6
Carl Allen, Baylor College of Medicine, USA
Short Talk: BRAF-V600E Is Identified in Circulating Myelomonocytic Precursors in Patients with High-Risk Langerhans Cell Histiocytosis

Thursday, March 07 | 8:00AM - 11:15AM
Role of DC in Pathogenesis
Room: Grays Peak

Speaker 6 of 6
Jesse Warren Williams, Washington University, USA
Short Talk: Interferon Regulatory Factor 4 (IRF4) in Dendritic Cells (DCs) Promotes Th2 Responses and Regulates IL-10 and IL-33 Production

Thursday, March 07 | 9:00AM - 9:20AM
Coffee Break
Room: Longs Peak Foyer


Thursday, March 07 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 1 of 10
* Florent Ginhoux, Singapore Immunology Network, Singapore

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 2 of 10
* Zoltan Fehervari, Nature Publishing Group, UK

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 3 of 10
Heidi A. Schreiber, Rockefeller University, USA
Comparing pre-DC and Monocyte-Derived Cell Heterogeneity and Function in Non-Lymphoid Organs

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 4 of 10
Wing-Hong Kwan, Mount Sinai School of Medicine, USA
Complement Proteins Produced by Dendritic Cells Control Effector T Cell Differentiation and Regulatory T Cell Function

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 5 of 10
Sotaro Ochiai, Malaghan Institute of Medical Research, New Zealand
TSLP-Dependent and Independent Induction of Th2 Responses via Dermal Dendritic Cells

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 6 of 10
Juliana Idoyaga, Rockefeller University, USA
Specialized Role of Migratory Dendritic Cells in Peripheral Tolerance Induction

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 7 of 10
Nir Yogev, University of Mainz, Germany
Dendritic Cells Control CNS Autoimmunity by Induction of Tregs through PD-L/PD-1 Interaction

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 8 of 10
Nathalie Bendriss-Vermare, Cancer Research Center of Lyon, France
Plasmacytoid Dendritic Cells Deficient in IFN-alpha Production Promote the Amplification of FOXP3+ Regulatory T Cells though ICOS/ICOS-L Interaction in Breast Cancer

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 9 of 10
Suryasarathi Dasgupta, Takeda California, Inc., USA
Critical Role of Plasmacytoid Dendritic Cells in Immunoregulation Initiated by a Commensal Microbial Polysaccharide

Thursday, March 07 | 2:30PM - 4:30PM
Workshop 3: Role of DC in Pathogenesis
Room: Grays Peak

Speaker 10 of 10
Teja Celhar, Singapore Immunology Network, Singapore
Enhanced RNA-Sensing in Dendritic Cells (DCs) Is Required for the Development of Severe Disease in SLE-Prone Mice

Thursday, March 07 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, March 07 | 5:00PM - 6:30PM
Harnessing DC Biology to Advance Disease Therapies
Room: Grays Peak

Speaker 1 of 4
* Ira Mellman, Genentech, Inc., USA

Thursday, March 07 | 5:00PM - 6:30PM
Harnessing DC Biology to Advance Disease Therapies
Room: Grays Peak

Speaker 2 of 4
* A. Karolina Palucka, The Jackson Laboratory for Genomic Medicine, USA
Reprogramming the Immune Environment in Cancer via Dendritic Cells

Thursday, March 07 | 5:00PM - 6:30PM
Harnessing DC Biology to Advance Disease Therapies
Room: Grays Peak

Speaker 3 of 4
Bana Jabri, University of Chicago, USA
DC in Celiac Disease

Thursday, March 07 | 5:00PM - 6:30PM
Harnessing DC Biology to Advance Disease Therapies
Room: Grays Peak

Speaker 4 of 4
Franck J. Barrat, Hospital for Special Surgery, USA
TLR Recognition of Self Nucleic Acids in Acute and Chronic Inflammation

Thursday, March 07 | 6:30PM - 7:15PM
Concluding Remarks

Speaker 1 of 1
Ira Mellman, Genentech, Inc., USA
Translating DC Biology into Medicine

Thursday, March 07 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys


Thursday, March 07 | 8:00PM - 11:00PM
Entertainment
Room: Shavano/Torreys


Thursday, March 07 | 8:00PM - 11:00PM
Cash Bar
Room: Shavano/Torreys


Friday, March 08 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.