Web Desc
Epigenetic Marks and Cancer Drugs
Organizer(s): Ali Shilatifard
Date: March 20 - 25, 2013
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Sponsored by AVEO Oncology, Celgene Corporation, Genentech, Inc. and H3 Biomedicine Inc.
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Summary of Meeting:
To regulate the precise pattern of gene expression during development, eukaryotic cells have evolved to have multifaceted transcriptional machineries and chromatin states. The DNA within the eukaryotic nucleus is found in complex with histone proteins to form nucleosomes, the basic unit of chromatin. Detailed structural studies demonstrated that the N-terminal tails of each of the histones protrude outward beyond the gyres of DNA and can be posttranslationally modified. The modifications of histone tails could provide a landing pad for a diverse array of transcription factors, chromatin remodelers, and DNA-interacting proteins to regulate gene expression. Translocations and/or mutations in chromatin-modifying machineries that perturb the timing and/or pattern of gene expression can result in the pathogenesis of human diseases including cancer. Recent studies demonstrate that the misregulation of several of the histone-modifying enzymes can contribute to changes in the epigenetic state leading to disease development. Therefore, both the scientific and the pharmaceutical communities have concentrated on identifying the molecular function for many of the histone-modifying machineries and are in the process of developing small molecular inhibitors of their activities in the hope of their use for targeted therapeutics of cancer. This Keystone Symposia meeting on Epigenetic Marks and Cancer Drugs serves as a much-needed platform for bringing both the scientific and the pharmaceutical communities together to discuss recent advances in this very exciting area.
Scholarship Deadline: November 19 2012
Discounted Abstract Deadline: November 19 2012
Abstract Deadline: December 21 2012
Discounted Registration Deadline: January 22 2013
Abstacts when book is in proofing process


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
AVEO OncologyCelgene CorporationGenentech, Inc.H3 Biomedicine Inc.
We gratefully acknowledge additional support for this conference from:
Cell Signaling Technology, Inc.Epizyme, Inc.Novus Biologicals, Inc.ROCKLAND IMMUNOCHEMICALS, Inc.Zymo Research Corporation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Constellation Pharmaceuticals

Epizyme, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA177246-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Wednesday, March 20 | 4:00PM - 8:00PM
Arrival and Registration
Room: North Concourse


Thursday, March 21 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Thursday, March 21 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Anasazi Ballroom

Speaker 1 of 1
Stuart L. Schreiber, HHMI/Harvard University, USA
Linking Genetic Features of Human Cancers and Histone-Modifying Enzymes for Future Cancer Therapies

Thursday, March 21 | 9:00AM - 11:00AM
Chromosomes, Chromatin and Transcription I
Room: Anasazi Ballroom

Speaker 1 of 6
* Shelley L. Berger, University of Pennsylvania, USA

Thursday, March 21 | 9:00AM - 11:00AM
Chromosomes, Chromatin and Transcription I
Room: Anasazi Ballroom

Speaker 2 of 6
B. Franklin Pugh, Pennsylvania State University, USA
Hemisomes and Nucleosomal Assymeetry across the Saccharomyces cerevisiae Genome

Thursday, March 21 | 9:00AM - 11:00AM
Chromosomes, Chromatin and Transcription I
Room: Anasazi Ballroom

Speaker 3 of 6
Patrick Cramer, Max Planck Institute for Biophysical Chemistry, Germany
New Insights into the Mechanisms of Transcription and its Regulation

Thursday, March 21 | 9:00AM - 11:00AM
Chromosomes, Chromatin and Transcription I
Room: Anasazi Ballroom

Speaker 4 of 6
Anne Brunet, Stanford University, USA
Epigenetic Regulation of Aging

Thursday, March 21 | 9:00AM - 11:00AM
Chromosomes, Chromatin and Transcription I
Room: Anasazi Ballroom

Speaker 5 of 6
Siavash K. Kurdistani, University of California, Los Angeles, USA
Short Talk: Regulation of Intracellular pH by Histone Acetylation

Thursday, March 21 | 9:00AM - 11:00AM
Chromosomes, Chromatin and Transcription I
Room: Anasazi Ballroom

Speaker 6 of 6
Alejandro Vaquero, Bellvitge Institute for Biomedical Research, Spain
Short Talk: SirT2 Regulates Cell Cycle Progression and Genome Stability by Modulating Mitotic Deposition of H4K20 Methylation

Thursday, March 21 | 9:40AM - 10:00AM
Coffee Break
Room: Concourse


Thursday, March 21 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Thursday, March 21 | 11:00AM - 1:00PM
Poster Setup
Room: Pavilion


Thursday, March 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Pavilion


Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 1 of 7
* Mary Ann Osley, University of New Mexico School of Medicine, USA

Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 2 of 7
Masami Horikoshi, University of Tokyo, Japan
“Modification Web” and “Signal Router” Theories on Histone Modification System and their Application to Development of Cancer Drugs

Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 3 of 7
Cigall Kadoch, Dana-Farber Cancer Institute, Harvard Medical School, USA
Reversible Disruption of mSWI/SNF-Like BAF Complexes by the SS18-SSX Oncogenic Fusion in Synovial Sarcoma

Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 4 of 7
Gary Hon, University of Texas Southwestern Medical Center, USA
Whole Genome Bisulfite Sequencing Reveals Tissue-Specific DNA Methylation in a Normal Mouse

Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 5 of 7
Tal H. Salz, Johns Hopkins University, USA
hSET1 Regulates the Canonical Wnt-Signaling Pathway and Plays a Role in Colorectal Cancer

Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 6 of 7
Eleni Maniati, Queen Mary University of London, UK
Functional Effect of Aberrant Mll2/3 Gene Expression in Pancreatic Cancer

Thursday, March 21 | 2:30PM - 4:30PM
Workshop 1
Room: Anasazi Ballroom

Speaker 7 of 7
Cheng-Fu Kao, Academia Sinica, Taiwan
H2B Monoubiquitylation Regulates the Replication Stress Response

Thursday, March 21 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Thursday, March 21 | 5:00PM - 7:00PM
Chromosomes, Chromatin and Transcription II
Room: Anasazi Ballroom

Speaker 1 of 6
* Ali Shilatifard, Northwestern University, USA

Thursday, March 21 | 5:00PM - 7:00PM
Chromosomes, Chromatin and Transcription II
Room: Anasazi Ballroom

Speaker 2 of 6
Richard A. Young, Whitehead Institute for Biomedical Research, USA
Connecting Transcription, Chromatin and Cancer

Thursday, March 21 | 5:00PM - 7:00PM
Chromosomes, Chromatin and Transcription II
Room: Anasazi Ballroom

Speaker 3 of 6
Shiv I. S. Grewal, NCI, National Institutes of Health, USA
Epigenetic Genome Control by RNAi and Heterochromatin Proteins

Thursday, March 21 | 5:00PM - 7:00PM
Chromosomes, Chromatin and Transcription II
Room: Anasazi Ballroom

Speaker 4 of 6
Anne Schaefer, Mount Sinai School of Medicine, USA
Short Talk: PRC2 is Essential for Adult Brain Function

Thursday, March 21 | 5:00PM - 7:00PM
Chromosomes, Chromatin and Transcription II
Room: Anasazi Ballroom

Speaker 5 of 6
Johnathan R. Whetstine, Fox Chase Cancer Center, USA
Short Talk: Looking at Cancer through the Eyes of Histone Demethylases

Thursday, March 21 | 5:00PM - 7:00PM
Chromosomes, Chromatin and Transcription II
Room: Anasazi Ballroom

Speaker 6 of 6
Charles Lin, Baylor College of Medicine, USA
Short Talk: Transcription Amplification in Tumor Cells with Elevated c-Myc

Thursday, March 21 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pavilion


Thursday, March 21 | 7:30PM - 10:00PM
Poster Session 1
Room: Pavilion


Friday, March 22 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 1 of 8
* Shiv I. S. Grewal, NCI, National Institutes of Health, USA

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 2 of 8
Ali Shilatifard, Northwestern University, USA
Chromatin Modifications, Transcriptional Elongation Control and Childhood Leukemia

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 3 of 8
Danny F. Reinberg, HHMI/New York University, USA
PRC1 in Drosophila and Mammals

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 4 of 8
Jürg Müller, Max Planck Institute of Biochemistry, Germany
Molecular Mechanisms of the Polycomb System

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 5 of 8
Peter Verrijzer, Erasmus University Medical Center, Netherlands
Antagonism between Polycomb and Trithorax in Development and Disease

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 6 of 8
Kami Ahmad, Harvard Medical School, USA
Short Talk: The Chromatin Configuration of Polycomb Response Elements (PREs) Define Epigenetic States

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 7 of 8
François Fuks, Université Libre de Bruxelles, Belgium
Short Talk: Molecular Basis of Tets: In Search of their Protein Partners

Friday, March 22 | 8:00AM - 11:00AM
Polycomb and Trithorax in Gene Expression and Cancer
Room: Anasazi Ballroom

Speaker 8 of 8
Zhiguo Zhang, Mayo Clinic, USA
Short Talk: Histone Modifications Regulate DNA Replication Coupled Nucleosome Assembly

Friday, March 22 | 9:20AM - 9:40AM
Coffee Break
Room: Concourse


Friday, March 22 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Friday, March 22 | 11:00AM - 1:00PM
Poster Setup
Room: Pavilion


Friday, March 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Pavilion


Friday, March 22 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Friday, March 22 | 5:00PM - 7:00PM
Histone Marks in Development and Cancer
Room: Anasazi Ballroom

Speaker 1 of 6
* Ramin Shiekhattar, University of Miami, USA

Friday, March 22 | 5:00PM - 7:00PM
Histone Marks in Development and Cancer
Room: Anasazi Ballroom

Speaker 2 of 6
Thomas Jenuwein, Max Planck Institute of Immunobiology and Epigenetics, Germany
Making and Breaking Heterochromatin

Friday, March 22 | 5:00PM - 7:00PM
Histone Marks in Development and Cancer
Room: Anasazi Ballroom

Speaker 3 of 6
Tony Kouzarides, University of Cambridge, UK
Chromatin Modification Pathways and their Role in Cancer

Friday, March 22 | 5:00PM - 7:00PM
Histone Marks in Development and Cancer
Room: Anasazi Ballroom

Speaker 4 of 6
Alexander Tarakhovsky, Rockefeller University, USA
Signaling Control of Epigenetic Fitness

Friday, March 22 | 5:00PM - 7:00PM
Histone Marks in Development and Cancer
Room: Anasazi Ballroom

Speaker 5 of 6
Shelley L. Berger, University of Pennsylvania, USA
Chromatin Landscape in Cellular Aging

Friday, March 22 | 5:00PM - 7:00PM
Histone Marks in Development and Cancer
Room: Anasazi Ballroom

Speaker 6 of 6
Mary Ann Osley, University of New Mexico School of Medicine, USA
Short Talk: The Histone Modification Landscape of Quiescent Yeast Cells Formed during Chronological Aging

Friday, March 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pavilion


Friday, March 22 | 7:30PM - 10:00PM
Poster Session 2
Room: Pavilion


Saturday, March 23 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 1 of 8
* B. Franklin Pugh, Pennsylvania State University, USA

Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 2 of 8
Yi Zhang, HHMI/Harvard Medical School, Children's Hospital Boston, USA
Role of Tet1-Mediated 5mC Oxidation in PGC Reprogramming and Meiosis

Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 3 of 8
Peter A. Jones, Van Andel Research Institute, USA
DNA Methylation and Cancer Therapy

Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 4 of 8
Jean-Pierre Issa, Temple University School of Medicine, USA
Epigenetic Reprogramming as Cancer Therapy

Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 5 of 8
Roger Greenberg, University of Pennsylvania, USA
Short Talk: Acetylation Determines Double-Strand Break Repair Choice and Response to PARP Inhibition

Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 6 of 8
Gregory David, New York University School of Medicine, USA
Short Talk: Epigenetic Regulation of Inflammation Modulates KRas-Driven Pancreatic Cancer Progression

Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 7 of 8
Diana Hargreaves, Stanford University, USA
Short Talk: BAF Complexes Cooperate with
Topoisomerase II alpha to Decatenate DNA


Saturday, March 23 | 8:00AM - 11:00AM
DNA Methylation in Development and Cancer
Room: Anasazi Ballroom

Speaker 8 of 8
Li-Jung Juan, Academia Sinica, Taiwan
Short Talk: Mechanisms of DNA Demethylation Enzymes TET Family Proteins in Suppressing Tumor Malignancy

Saturday, March 23 | 9:20AM - 9:40AM
Coffee Break
Room: Concourse


Saturday, March 23 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Saturday, March 23 | 11:00AM - 1:00PM
Poster Setup
Room: Pavilion


Saturday, March 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Pavilion


Saturday, March 23 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Saturday, March 23 | 5:00PM - 7:00PM
Enhancers and ncRNAs in Development and Cancer
Room: Anasazi Ballroom

Speaker 1 of 5
* Peter Verrijzer, Erasmus University Medical Center, Netherlands

Saturday, March 23 | 5:00PM - 7:00PM
Enhancers and ncRNAs in Development and Cancer
Room: Anasazi Ballroom

Speaker 2 of 5
Ramin Shiekhattar, University of Miami, USA
Brave New World of Noncoding RNA

Saturday, March 23 | 5:00PM - 7:00PM
Enhancers and ncRNAs in Development and Cancer
Room: Anasazi Ballroom

Speaker 3 of 5
Jeannie T. Lee, Massachusetts General Hospital / Harvard Medical School, USA
Xist RNA in the Establishment and Maintenance of X Chromosome Inactivation

Saturday, March 23 | 5:00PM - 7:00PM
Enhancers and ncRNAs in Development and Cancer
Room: Anasazi Ballroom

Speaker 4 of 5
Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Inheritance and Reprogramming of Heterochromatin with Small RNA

Saturday, March 23 | 5:00PM - 7:00PM
Enhancers and ncRNAs in Development and Cancer
Room: Anasazi Ballroom

Speaker 5 of 5
Celso A. Espinoza, AbbVie Inc., USA
Short Talk: Architectural Studies of Intramolecular Interactions between Enhancers and Promoters via ChIP-HiC

Saturday, March 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Pavilion


Saturday, March 23 | 7:30PM - 10:00PM
Poster Session 3
Room: Pavilion


Sunday, March 24 | 7:00AM - 8:00AM
Breakfast
Room: Eldorado Court


Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 1 of 8
* Kapil N. Bhalla, MD Anderson Cancer Center, USA

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 2 of 8
Robert N. Eisenman, Fred Hutchinson Cancer Research Center, USA
Cooperative Transcriptional Regulation of Metabolism Mediated by the Myc-Max/MondoA-Mlx Network

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 3 of 8
Michael D. Cole, Dartmouth Medical School, USA
An Epigenetic Model for Myc Autoregulation and Gene Repression

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 4 of 8
Bruno Amati, Italian Institute of Technology and European Institute of Oncology, Italy
Epigenome and Transcriptome Regulation in Myc-Driven Tumors

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 5 of 8
James E. Bradner, Novartis Institutes for BioMedical Research, USA
Targeting Gene Regulatory Pathways

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 6 of 8
Lin-Feng Chen, University of Illinois at Urbana-Champaign, USA
Short Talk: Brd4 Maintains Constitutively Active NF-kappaB in Cancer Cells by Binding to Acetylated RelA

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 7 of 8
Junwei Shi, Cold Spring Harbor Laboratory, USA
Short Talk: Collaboration between the BAF Complex and Brd4 Maintains Myc Expression in Leukemia

Sunday, March 24 | 8:00AM - 11:00AM
Myc, Transcriptional Regulation and Development
Room: Anasazi Ballroom

Speaker 8 of 8
Katherine A. Jones, The Salk Institute, USA
Short Talk: Beta-Catenin Ubiquitylation and Release from LEF-1/TCF by a Novel alpha-Catenin:APC Complex

Sunday, March 24 | 9:20AM - 9:40AM
Coffee Break
Room: Concourse


Sunday, March 24 | 10:00AM - 10:00AM
On Own for Lunch and Recreation


Sunday, March 24 | 2:30PM - 4:30PM
Workshop 2
Room: Anasazi Ballroom

Speaker 1 of 6
* Roger Greenberg, University of Pennsylvania, USA

Sunday, March 24 | 2:30PM - 4:30PM
Workshop 2
Room: Anasazi Ballroom

Speaker 2 of 6
Klaas Kok, University Medical Center Groningen, Netherlands
The Impact of SETD2-Inactivating Mutations and Loss of H3K36 Trimethylation on Gene Expression in Clear Cell Renal Cell Carcinoma Progenitor Cells

Sunday, March 24 | 2:30PM - 4:30PM
Workshop 2
Room: Anasazi Ballroom

Speaker 3 of 6
Hao A. Duong, Harvard Medical School, USA
Temporal Coordination of Histone De-Acetylase and Methyl-Transferase in Circadian Transcriptional Repression

Sunday, March 24 | 2:30PM - 4:30PM
Workshop 2
Room: Anasazi Ballroom

Speaker 4 of 6
Seung Hyuk Choi, The Salk Institute, USA
Role for alpha-Catenin in APC-Mediated Repression at Wnt Target Genes

Sunday, March 24 | 2:30PM - 4:30PM
Workshop 2
Room: Anasazi Ballroom

Speaker 5 of 6
Emily A. Clough, NIDDK, National Institutes of Health, USA
The H4K16 Histone Acetyltransferase Chameau Is a Putative Target of Doublesex

Sunday, March 24 | 2:30PM - 4:30PM
Workshop 2
Room: Anasazi Ballroom

Speaker 6 of 6
Anil K. Panigrahi, Baylor College of Medicine, USA
Dissecting the Role of H3K79 Methylation in Transcription Elongation and Leukemia

Sunday, March 24 | 4:30PM - 5:00PM
Coffee Available
Room: Concourse


Sunday, March 24 | 5:00PM - 7:15PM
Transcription, Chromatin and Epigenetics in Cancer Therapy
Room: Anasazi Ballroom

Speaker 1 of 6
* Robert N. Eisenman, Fred Hutchinson Cancer Research Center, USA

Sunday, March 24 | 5:00PM - 7:15PM
Transcription, Chromatin and Epigenetics in Cancer Therapy
Room: Anasazi Ballroom

Speaker 2 of 6
Laurie A. Boyer, Massachusetts Institute of Technology, USA
Developmental Transitions in Heart Development

Sunday, March 24 | 5:00PM - 7:15PM
Transcription, Chromatin and Epigenetics in Cancer Therapy
Room: Anasazi Ballroom

Speaker 3 of 6
Robert J. Gould, Fulcrum Therapeutics, USA
Drugging the Human Methylome: Discovery and Characterization of Inhibitors of Protein Methyltransferases for the Treatment of Genetically Defined Cancers

Sunday, March 24 | 5:00PM - 7:15PM
Transcription, Chromatin and Epigenetics in Cancer Therapy
Room: Anasazi Ballroom

Speaker 4 of 6
Patrick Trojer, Constellation Pharmaceuticals, USA
Targeting Histone Lysine Methylation in Cancer

Sunday, March 24 | 5:00PM - 7:15PM
Transcription, Chromatin and Epigenetics in Cancer Therapy
Room: Anasazi Ballroom

Speaker 5 of 6
Marie Classon, USA
Short Talk: Chromatin Modifications and the Establishment of Drug-Tolerance

Sunday, March 24 | 5:00PM - 7:15PM
Transcription, Chromatin and Epigenetics in Cancer Therapy
Room: Anasazi Ballroom

Speaker 6 of 6
Kapil N. Bhalla, MD Anderson Cancer Center, USA
Short Talk: Highly Effective Combination of LSD1 Antagonist SP-2509 and Pan-HDAC Inhibitor Against Human AML Cells

Sunday, March 24 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Pavilion


Sunday, March 24 | 8:00PM - 11:00PM
Entertainment
Room: Pavilion


Sunday, March 24 | 8:15PM - 11:00PM
Cash Bar
Room: Pavilion


Monday, March 25 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.