Web Desc
The Innate Immune Response in the Pathogenesis of Infectious Disease
Organizer(s): Ricardo T. Gazzineli, Gustavo P. Amarante-Mendes, Anne O'Garra and Alan Sher
Date: May 10 - 15, 2013
Location: Centro de Artes e Convenções (UFOP), Ouro Preto, Minas Gerais, Brazil
Organized as an international collaboration and with generous support from CNPq — the National Council for Scientific and Technological Development, Brazil, and FAPEMIG — Minas Gerais State Agency for Research Development. Part of the Keystone Symposia Global Health Series, travel awards supported by the Bill & Melinda Gates Foundation.
Summary of Meeting:
The rational development of immunological interventions that are effective for treating or preventing infectious diseases is still on its infancy. For decades, the majority of the studies on immunopathogenesis have dealt with physical damage and inflammation, primarily mediated by lymphocytes. The main focus of this Keystone Symposia meeting will be on the interface of the innate immune system and microbial pathogens and the role that it plays in protective versus deleterious immune responses and, thereby, of disease outcome. The program will promote discussions on fundamental concepts as well as new advances in the role of innate immunity in host resistance and pathogenesis of infectious diseases, with special emphasis on infections of the tropics. Investigators from different areas, such as biochemistry, cell biology, immunology, microbiology, parasitology, infectious diseases, tropical medicine and biotechnology will be included to encourage the discussion of interdisciplinary concepts and new directions for the field. This is the first of a series of Keystone Symposia meetings to be held in Brazil, and should also foster the participation of Latin American students and scientists. The close interaction of these participants with leading international experts in the field should lead to a stimulating atmosphere that we hope will promote the development of new South-North collaborations and research networks.
Global Health Travel Award Deadline: December 11 2012
Scholarship Deadline: January 7 2013
Discounted Abstract Deadline: January 7 2013
Abstract Deadline: February 4 2013
Discounted Registration Deadline: March 5 2013
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Bill & Melinda Gates FoundationCNPq - the National Council for Scientific and Technological Development, BrazilFAPEMIG - Minas Gerais State Agency for Development Research
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Dynavax Technologies Corporation
$2,500 - $9,999
S. Karger AG - Journal of Innate Immunity
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
S. Karger AG - Journal of Innate Immunity
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI106140-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Friday, May 10 | 3:00PM - 7:30PM
Arrival and Registration
Room: Foyer/Diamantina


Friday, May 10 | 6:15PM - 7:15PM
Refreshments
Room: Foyer/Diamantina


Friday, May 10 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Teatro Ouro Preto

Speaker 1 of 2
* Rodrigo Corrêa-Oliveira, FIOCRUZ, Brazil
Keystone Symposia Brazil and the Challenges of Global Tropical Diseases

Friday, May 10 | 7:15PM - 9:30PM
Welcome and Keynote Session
Room: Teatro Ouro Preto

Speaker 2 of 2
Jean-Laurent Casanova, Rockefeller University, USA
Toward a Genetic Theory of Infectious Diseases

Saturday, May 11 | 7:30AM - 8:30AM
Breakfast
Room: Your Lodging


Saturday, May 11 | 8:00AM - 10:00AM
Poster Setup
Room: Diamantina


Saturday, May 11 | 8:30AM - 11:30AM
Innate Immune Recognition
Room: Teatro Ouro Preto

Speaker 1 of 6
* Vishva M. Dixit, Genentech, Inc., USA
Non-Canonical Inflammasome Activation Targets Caspase-11

Saturday, May 11 | 8:30AM - 11:30AM
Innate Immune Recognition
Room: Teatro Ouro Preto

Speaker 2 of 6
Kate A. Fitzgerald, University of Massachusetts Medical School, USA
Regulation of Inflammatory Gene Expression by Long Noncoding RNAs

Saturday, May 11 | 8:30AM - 11:30AM
Innate Immune Recognition
Room: Teatro Ouro Preto

Speaker 3 of 6
Julie Magarian Blander, Weill Cornell Medicine, Cornell University, USA
Detecting and Responding to Microbial Viability

Saturday, May 11 | 8:30AM - 11:30AM
Innate Immune Recognition
Room: Teatro Ouro Preto

Speaker 4 of 6
Egil Lien, University of Massachusetts Medical School, USA
Short Talk: Innate Immunity to Plague

Saturday, May 11 | 8:30AM - 11:30AM
Innate Immune Recognition
Room: Teatro Ouro Preto

Speaker 5 of 6
Sun Hur, Harvard Medical School, USA
Short Talk: Molecular Mechanism for Viral dsRNA Detection by MDA5 Filaments

Saturday, May 11 | 8:30AM - 11:30AM
Innate Immune Recognition
Room: Teatro Ouro Preto

Speaker 6 of 6
Jamie Lemon, University of Pennsylvania, USA
Short Talk: Cytosolic Access and Sensing of Components of Extracellular Bacteria by Macrophages

Saturday, May 11 | 9:50AM - 10:10AM
Coffee Break
Room: Diamantina


Saturday, May 11 | 11:30AM - 12:30PM
Lunch
Room: Diamantina


Saturday, May 11 | 12:00PM - 2:30PM
Poster Session 1
Room: Diamantina


Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 1 of 10
* Marcelo T. Bozza, Universidade Federal do Rio de Janeiro, Brazil

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 2 of 10
* Koichi S. Kobayashi, Texas A&M Health Science Center, USA

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 3 of 10
Jiaxi Wu, Regeneron,Inc., USA
Identification of Cyclic-GMP-AMP (cGAMP) and Cyclic-GMP-AMP Synthase (cGAS) as Important Cytosolic DNA Sensing Mediators

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 4 of 10
Andrea Puhar, Umeå University, Sweden
Shigella Effector IpgD Dampens Inflammation by Securing Hemichannel Closing through Production of PdtIns5P, Thereby Inhibiting Extracellular ATP-Mediated Endogenous Danger Signaling

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 5 of 10
Rune Hartmann, Aarhus University, Denmark
The Oligoadenylate Synthetase Like Protein (OASL) Enhances Viral Recognition and Interferon Production by Infected Cells

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 6 of 10
Warrison A. Andrade, Faculdade de Medicina de Ribeirão Preto - FMRP-USP, Brazil
Combined Action of Nucleic Acid-Sensing Toll-Like Receptors (TLRs) and TLR11/TLR12 Heterodimers Imparts Host Resistance to Toxoplasma gondii

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 7 of 10
Jane Rasaiyaah, University College London, UK
Inhibition of HIV-1-Cofactor Interactions Triggers Innate Sensors and Interferon Secretion

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 8 of 10
Anamelia Lorenzetti Bocca, Universidade de Brasília, Brazil
Beta-Glucan Reverts the Macrophage Inability to Kill Cryptococcus neoformans in vitro

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 9 of 10
Sterling C. Eckard, University of Washington, USA
Intracellular Nucleic Acid Metabolism Limits the RIG-I-Mediated Antiviral Response

Saturday, May 11 | 2:30PM - 4:30PM
Workshop 1: Innate Recognition and Signaling
Room: Teatro Ouro Preto

Speaker 10 of 10
Felix Meissner, Max Planck Institute of Biochemistry, Germany
Secretomics Defines How Proximal Adaptors of TLRs Regulate Inflammation

Saturday, May 11 | 4:30PM - 5:00PM
Coffee Available
Room: Diamantina


Saturday, May 11 | 5:00PM - 7:00PM
Innate Immunity in Vectors
Room: Teatro Ouro Preto

Speaker 1 of 4
* Elena A. Levashina, Max Planck Institute for Infection Biology, Germany
Mechanisms of Innate Resistance to Malaria Parasites in the Mosquito

Saturday, May 11 | 5:00PM - 7:00PM
Innate Immunity in Vectors
Room: Teatro Ouro Preto

Speaker 2 of 4
George Dimopoulos, Johns Hopkins University, USA
Innate and Microbiota-Mediated Control of Dengue Virus in Mosquitoes

Saturday, May 11 | 5:00PM - 7:00PM
Innate Immunity in Vectors
Room: Teatro Ouro Preto

Speaker 3 of 4
Simona Paro, IBMC-CNRS/Université de Strasbourg, France
Short Talk: Sensing Viral Nucleic Acids by the Innate Immune System: Lessons from Drosophila

Saturday, May 11 | 5:00PM - 7:00PM
Innate Immunity in Vectors
Room: Teatro Ouro Preto

Speaker 4 of 4
David L. Sacks, NIAID, National Institutes of Health, USA
Influence of Vector Transmission on the Innate Immune Response to Leishmania major

Saturday, May 11 | 7:00PM - 7:00PM
On Own for Dinner


Sunday, May 12 | 7:30AM - 8:30AM
Breakfast
Room: Your Lodging


Sunday, May 12 | 8:30AM - 11:45AM
Innate Lymphoid Cells (ILC) and Mucosal Immunity
Room: Teatro Ouro Preto

Speaker 1 of 6
* Fiona M. Powrie, University of Oxford, UK
IL-23-Driven Cellular and Molecular Pathways that Promote Intestinal Inflammation and Colon Cancer

Sunday, May 12 | 8:30AM - 11:45AM
Innate Lymphoid Cells (ILC) and Mucosal Immunity
Room: Teatro Ouro Preto

Speaker 2 of 6
David Artis, Weill Cornell Medical College, USA
Regulation of Innate and Adaptive Immunity at Barrier Surfaces

Sunday, May 12 | 8:30AM - 11:45AM
Innate Lymphoid Cells (ILC) and Mucosal Immunity
Room: Teatro Ouro Preto

Speaker 3 of 6
Dan R. Littman, HHMI/New York University School of Medicine, USA
Microbiota-Host Interactions in T Cell Homeostasis and Autoimmune Disease

Sunday, May 12 | 8:30AM - 11:45AM
Innate Lymphoid Cells (ILC) and Mucosal Immunity
Room: Teatro Ouro Preto

Speaker 4 of 6
Marco Colonna, Washington University School of Medicine, USA
Innate Lymphoid Cells in Mucosal Immunity

Sunday, May 12 | 8:30AM - 11:45AM
Innate Lymphoid Cells (ILC) and Mucosal Immunity
Room: Teatro Ouro Preto

Speaker 5 of 6
Lucille Rankin, Walter and Eliza Hall Institute of Medical Research, Australia
Short Talk: T-bet Is Required for the Development of NKp46+ Innate Lymphoid Cells via a Notch Dependent Pathway

Sunday, May 12 | 8:30AM - 11:45AM
Innate Lymphoid Cells (ILC) and Mucosal Immunity
Room: Teatro Ouro Preto

Speaker 6 of 6
Kevin J. Maloy, University of Oxford, UK
Nlrp3 Inflammasome Activation in the Intestinal Epithelium Protects Against a Mucosal Pathogen

Sunday, May 12 | 9:50AM - 10:10AM
Coffee Break
Room: Diamantina


Sunday, May 12 | 11:45AM - 1:00PM
Poster Setup
Room: Diamantina


Sunday, May 12 | 11:45AM - 11:45AM
On Own for Lunch and Recreation


Sunday, May 12 | 4:30PM - 5:00PM
Coffee Available
Room: Diamantina


Sunday, May 12 | 5:00PM - 7:15PM
Effector Mechanisms
Room: Teatro Ouro Preto

Speaker 1 of 5
* Arturo Zychlinsky, Max Planck Institute for Infection Biology, Germany
NETs – From Infection to Autoimmunity

Sunday, May 12 | 5:00PM - 7:15PM
Effector Mechanisms
Room: Teatro Ouro Preto

Speaker 2 of 5
Judith E. Allen, University of Manchester, UK
Macrophages in Helminth Infection

Sunday, May 12 | 5:00PM - 7:15PM
Effector Mechanisms
Room: Teatro Ouro Preto

Speaker 3 of 5
Jonathan Howard, Instituto Gulbenkian de Ciência, Portugal
Genetic Basis of Innate Immune Control of a Parasitic Disease

Sunday, May 12 | 5:00PM - 7:15PM
Effector Mechanisms
Room: Teatro Ouro Preto

Speaker 4 of 5
Dario S. Zamboni, University of São Paulo, Brazil
Short Talk: Inflammasome-Mediated Innate Immune Responses to Leishmania

Sunday, May 12 | 5:00PM - 7:15PM
Effector Mechanisms
Room: Teatro Ouro Preto

Speaker 5 of 5
Lynda M. Stuart, Bill & Melinda Gates Foundation, USA
Short Talk: Activation of Caspase-1 by the NLRP3 Inflammasome Regulates NOX2 to Control Phagosome Function

Sunday, May 12 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Diamantina


Sunday, May 12 | 7:30PM - 10:00PM
Poster Session 2
Room: Diamantina


Monday, May 13 | 7:30AM - 8:30AM
Breakfast
Room: Your Lodging


Monday, May 13 | 8:30AM - 11:45AM
Innate Cytokines Influencing Adaptive Immunity and Inflammat
ion

Room: Teatro Ouro Preto

Speaker 1 of 6
* Alan Sher, NIAID, National Institutes of Health, USA
TLR12: A New Player in Innate Recognition and Host Resistance to Protozoan Infection

Monday, May 13 | 8:30AM - 11:45AM
Innate Cytokines Influencing Adaptive Immunity and Inflammat
ion

Room: Teatro Ouro Preto

Speaker 2 of 6
Robert L. Coffman, Dynavax Technologies, USA
Clinical Applications of Innate Immune Signals

Monday, May 13 | 8:30AM - 11:45AM
Innate Cytokines Influencing Adaptive Immunity and Inflammat
ion

Room: Teatro Ouro Preto

Speaker 3 of 6
Kingston H.G. Mills, Trinity Biomedical Sciences Institute (TBSI), Ireland
Innate Determinates of Th1/Th17 versus Treg Cells

Monday, May 13 | 8:30AM - 11:45AM
Innate Cytokines Influencing Adaptive Immunity and Inflammat
ion

Room: Teatro Ouro Preto

Speaker 4 of 6
Edgar M. Carvalho, Universidade Federal da Bahia, Brazil
Innate Determinants in the Control and Pathology of Human Tegumentary Leishmaniasis

Monday, May 13 | 8:30AM - 11:45AM
Innate Cytokines Influencing Adaptive Immunity and Inflammat
ion

Room: Teatro Ouro Preto

Speaker 5 of 6
Katrijn Neyt, VIB, Ghent University, Belgium
Short Talk: The Innate Cytokine IL-1alpha Is Necessary and Sufficient for Formation of Tertiary Lymphoid Tissues following Influenza A Virus Infection

Monday, May 13 | 8:30AM - 11:45AM
Innate Cytokines Influencing Adaptive Immunity and Inflammat
ion

Room: Teatro Ouro Preto

Speaker 6 of 6
Andreas Wack, Francis Crick Institute, UK
Short Talk: Pathogenic Potential of Type I IFN in Influenza Infection

Monday, May 13 | 9:50AM - 10:10AM
Coffee Break
Room: Diamantina


Monday, May 13 | 9:50AM - 10:10AM
Poster Setup
Room: Diamantina


Monday, May 13 | 11:30AM - 12:30PM
Lunch
Room: Diamantina


Monday, May 13 | 12:00PM - 2:30PM
Poster Session 3
Room: Diamantina


Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 1 of 10
* Sergio Costa Oliveira, Universidade Federal de Minas Gerais, Brazil

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 2 of 10
* Kevin J. Maloy, University of Oxford, UK

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 3 of 10
David Sancho, CNIC-Fundación Centro Nacional de Investigaciones Cardiovasculares, Spain
Recognition of Leishmania Parasites by the Macrophage-Inducible C-Type Lectin Mincle Subverts Adaptive Immunity and Promotes Susceptibility to Infection

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 4 of 10
Jennifer Palomo, CNRS - INEM - UMR7355, France
Type I Interferons Contribute to Orchestrate IFNgamma Dependent Development of Experimental Cerebral Malaria

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 5 of 10
Maria Bellio, Universidade Federal do Rio de Janeiro, Brazil
Intrinsic IL-18R1 Signaling Pathway Plays a Crucial Role in Th1 Cell Expansion in Mice Infected with Trypanosoma cruzi

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 6 of 10
Catalina D. Alba Soto, Universidad de Buenos Aires, Argentina
Impairment of Natural Killer (NK) Cells Editing of Immature Dendritic Cells (DC) by Infection with a Virulent Trypanosoma cruzi Population

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 7 of 10
Gregory F. Sonnenberg, Weill Cornell Medicine, USA
Innate Lymphoid Cells Are Critical Regulators of Host Immune Responses to Bacteria and Intestinal Homeostasis

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 8 of 10
Shie-Liang Hsieh, Academia Sinica, Taiwan
C-Type Lectin 5A (CLEC5A) Is Critical for the Pathogenesis of Flaviviral Infections

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 9 of 10
Catherine L. Kennedy, University of Melbourne, Australia
Fas Signaling in Immune Defense Against the Intestinal Pathogen, Citrobacter rodentium

Monday, May 13 | 2:30PM - 4:30PM
Workshop 2: Cytokines, Inflammation and Pathogenesis
Room: Teatro Ouro Preto

Speaker 10 of 10
Monica Macal, Five Prime Therapeutics, Inc, USA
TLR7 Is Required for Both Plasmacytoid Dendritic Cell IFN-I Production and Subsequent Exhaustion during Chronic Viral Infection

Monday, May 13 | 4:30PM - 5:00PM
Coffee Available
Room: Diamantina


Monday, May 13 | 5:00PM - 7:15PM
Innate Signals in Disease Pathogenesis
Room: Teatro Ouro Preto

Speaker 1 of 5
Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA
Innate Immune Sensing and Signaling of Cytosolic DNA through a Cyclic Dinucleotide Pathway

Monday, May 13 | 5:00PM - 7:15PM
Innate Signals in Disease Pathogenesis
Room: Teatro Ouro Preto

Speaker 2 of 5
Douglas Golenbock, University of Massachusetts Medical School, USA
DNA Sensing Drives the Innate Immune Response in Malaria

Monday, May 13 | 5:00PM - 7:15PM
Innate Signals in Disease Pathogenesis
Room: Teatro Ouro Preto

Speaker 3 of 5
* Anne O'Garra, Francis Crick Institute, UK
The Immune Response in Tuberculosis: From Mouse Models to Human Disease

Monday, May 13 | 5:00PM - 7:15PM
Innate Signals in Disease Pathogenesis
Room: Teatro Ouro Preto

Speaker 4 of 5
Corey A. Balinsky, NIAID, National Institutes of Health, USA
Short Talk: NF45 Interacts with Dengue Virus Capsid Protein and Modulates Induction of Interferon Beta

Monday, May 13 | 5:00PM - 7:15PM
Innate Signals in Disease Pathogenesis
Room: Teatro Ouro Preto

Speaker 5 of 5
Sergio Costa Oliveira, Universidade Federal de Minas Gerais, Brazil
Short Talk: Critical Role of ASC Inflammasomes and Bacterial Type IV Secretion System in Caspase-1 Activation and Host Innate Resistance to Brucella abortus Infection

Monday, May 13 | 7:15PM - 7:15PM
On Own for Dinner


Tuesday, May 14 | 7:30AM - 8:30AM
Breakfast
Room: Your Lodging


Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 1 of 7
Douglas R. Green, St. Jude Children's Research Hospital, USA
Dead on Arrival: How Caspases Promote and Prevent Cell Death

Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 2 of 7
* Ricardo T. Gazzinelli, Fundação Oswaldo Cruz-CPqRR, Brazil
NLRP12/NLRP3-Dependent Caspase-1 Driven Inflammation in Malaria

Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 3 of 7
Maya Saleh, McGill University, Canada
cIAP2 Protects Mice from Alveolar Epithelial Injury during Influenza A Virus Infection

Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 4 of 7
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Inflammasome-Dependent and -Independent Regulation of IL-1 Cytokines in Inflammatory Disease

Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 5 of 7
Karina R. Bortoluci, Federal University of São Paulo, Brazil
Short Talk: Inflammasome-Independent Cell Death Induced by Cytosolic flagellin

Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 6 of 7
Edward A. Miao, University of North Carolina at Chapel Hill, USA
Non-Canonical Inflammasome Activation of Caspase-11 Protects Against Cytosolic Bacteria

Tuesday, May 14 | 8:30AM - 12:00PM
Cell Death in Host Resistance and Pathogenesis of Infectious
Diseases

Room: Teatro Ouro Preto

Speaker 7 of 7
Mohamed Lamkanfi, Ghent University, Belgium
Short Talk: Regulation of Nlrp3 Inflammasome Activation by the Ubiquitin-Editing Enzyme A20

Tuesday, May 14 | 9:50AM - 10:10AM
Coffee Break
Room: Diamantina


Tuesday, May 14 | 11:30AM - 11:30AM
On Own for Lunch and Recreation


Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 1 of 9
* Gustavo P. Amarante-Mendes, Universidade de São Paulo, Brazil

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 2 of 9
* Clare E. Bryant, University of Cambridge, UK
A Critical Link between Innate Immunity and Cellular Mechanics to Control Bacterial Load in Macrophages

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 3 of 9
Petr Broz, University of Lausanne, Switzerland
Caspase-11 Increases Susceptibility to Salmonella Infection in the Absence of Caspase-1

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 4 of 9
William J. Kaiser, Emory University School of Medicine, USA
Virus Inhibition of Caspase 8 Restricts Pathogenesis via RIP3-Dependent Programmed Necrosis

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 5 of 9
Marco A. Ataíde, Universidade Federal de Minas Gerais, Brazil
CD14dimCD16+ Monocytes Are a Main Source of Active Caspase-1 and IL-1beta Release during Plasmodium vivax Malaria

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 6 of 9
Vijay Pancholi, Ohio State University College of Medicine, USA
Group A Streptococcus Ser/Thr Phosphatase-Mediated Apoptosis of Human Respiratory Cells

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 7 of 9
Mordechay Gerlic, Sackler Faculty of Medicine, Tel Aviv University, Israel
EBV-miR-BART15 Regulates the Nlrp3 Inflammasome and IL-1beta Production

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 8 of 9
Ivan Tattoli, University of Toronto, Canada
mTOR Signaling and Metabolic Stress Response Pathways in the Host Response to Intracellular Bacteria

Tuesday, May 14 | 2:30PM - 4:30PM
Workshop 3: Cell Death and Pathogenesis
Room: Teatro Ouro Preto

Speaker 9 of 9
Larissa D. Cunha, Ribeirao Preto Medical School, University of Sao Paulo, Brazil
Coxiella burnetii Inhibits Inflammasome Activation through a Dot/Icm-Dependent Effector Protein

Tuesday, May 14 | 4:30PM - 5:00PM
Coffee Available
Room: Diamantina


Tuesday, May 14 | 5:00PM - 6:15PM
Immunological Adjuvants and Vaccines
Room: Teatro Ouro Preto

Speaker 1 of 2
* Jorge Kalil, Instituto Butantan, Brazil
Dengue Vaccine Candidates

Tuesday, May 14 | 5:00PM - 6:15PM
Immunological Adjuvants and Vaccines
Room: Teatro Ouro Preto

Speaker 2 of 2
Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA
Harnessing Human Dendritic Cell Subsets and Follicular Helper T Cell Subsets for Next Generation Vaccines

Tuesday, May 14 | 6:15PM - 7:00PM
Closing Keynote Address
Room: Teatro Ouro Preto

Speaker 1 of 1
Michel C. Nussenzweig, HHMI/Rockefeller University, USA
Targeting Dendritic Cells in Malaria Vaccine

Tuesday, May 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Diamantina


Tuesday, May 14 | 8:00PM - 11:00PM
Entertainment
Room: Diamantina


Tuesday, May 14 | 8:00PM - 11:00PM
Cash Bar
Room: Diamantina


Wednesday, May 15 | 10:25AM - 10:25AM
Departure


*Session Chair.