Web Desc
Type 2 Immunity: Initiation, Maintenance, Homeostasis and Pathology
joint with Pathogenic Processes in Asthma and COPD
Organizer(s): Richard M. Locksley and Judith E. Allen
Date: January 10 - 15, 2013
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA
Supported by an educational donation provided by Amgen
Summary of Meeting:
Diseases associated with allergy and asthma are increasing in developed countries, with great consequences to healthcare costs. Often, these diseases reflect pathologic outcomes of type 2 immunity, and are characterized by infiltration of tissues with Th2 cells and eosinophils, by elevations in serum IgE and by alterations in epithelial and mucosal biology. These responses did not evolve to cause allergies, and clues to the evolutionary pressure to maintain this type of immune response may exist in the response to intestinal helminths, which cause chronic infestations in all vertebrate species on earth. This meeting will bring together scientists from diverse disciplines to discuss new findings in type 2 immunity that suggest close associations of these responses with tissue homeostasis, mucosal microbiomes and immune integrity that optimize overall fitness of the organism. The goals of this meeting are as follows: 1) to identify gaps in our understanding of type 2 immunity and facilitate future research advances in the field; 2) to promote the development of novel therapeutic strategies against diseases associated with type 2 immunity; and 3) to encourage cross-disciplinary collaborations and establish an ongoing dialogue for future research. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on Pathogenic Processes in Asthma and COPD, which will share a keynote address and two plenary sessions with this meeting.
Scholarship Deadline: September 10 2012
Discounted Abstract Deadline: September 10 2012
Abstract Deadline: October 10 2012
Discounted Registration Deadline: November 8 2012
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Educational donation provided by Amgen
We gratefully acknowledge additional support for this conference from:
The Rockefeller University Press - The Journal of Experimental Medicine
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Genentech, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI102504-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Thursday, January 10 | 3:00PM - 7:30PM
Arrival and Registration
Room: Sweeney Ballroom Foyer


Thursday, January 10 | 6:15PM - 7:15PM
Refreshments
Room: Sweeney F, Main Level Breakouts


Thursday, January 10 | 7:15PM - 8:30PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 1
Bart N. Lambrecht, VIB, Ghent University, Belgium
The Lung Dendritic Cell Network and the Response to Allergens

Friday, January 11 | 7:00AM - 8:00AM
Breakfast
Room: Main Level Breakouts


Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 1 of 8
* Judith E. Allen, University of Manchester, UK

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 2 of 8
Maria Yazdanbakhsh, Leiden University Medical Center, Netherlands
Human Helminth Infections, Immune Responses and Inflammatory Diseases

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 3 of 8
Ajay Chawla, Merck Research Labs, USA
Metabolic (Regenerative) Consequences of Type 2 Immunity

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 4 of 8
Andrew S. MacDonald, University of Manchester, UK
Short Talk: Epigenetic Control of Th2 Induction by Dendritic Cells

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 5 of 8
Ilaria Mosconi, EPFL SV GHI UPHARRIS, Switzerland
Short Talk: Differential Role of Peyer’s Patches and Mesenteric Lymph Nodes during Helminth Infection

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 6 of 8
Hermelijn H. Smits, Leiden University Center, Netherlands
Short Talk: Human Schistosome-Induced IL-10 Producing CD1dhi B Cells Regulate Effector T Cell Responses

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 7 of 8
Mark A. Travis, University of Manchester, UK
Short Talk: The TGFbeta-Activating Integrin alphavbeta8 on Dendritic Cells Regulates Type 2 Immunity in the Intestine to Promote Chronic Parasitic Infection

Friday, January 11 | 8:00AM - 11:00AM
Adaptations to Chronic Helminth Infection
Room: Sweeney Ballroom A-B

Speaker 8 of 8
Barbara Platzer, Novartis Institutes for BioMedical Research, USA
Short Talk: Dendritic Cells use IgE as an Antigen Sensor for Regulating Th2 Immunity

Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 7
* Donata Vercelli, University of Arizona, USA


Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 7
Sally Wenzel-Morganroth, University of Pittsburgh, USA
Emerging Concepts on Asthma Heterogeneity


Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 7
Fernando D. Martinez, University of Arizona, USA
Early-Life Origins of Chronic Obstructive Pulmonary Disease


Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 7
Avrum Spira, Boston University, USA
Molecular Insights into COPD via Transcriptomic Profiling


Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 7
Ian M. Adcock, Imperial College London, UK
Epigenetic Regulation of Lung Disease


Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 6 of 7
Peter McErlean, Kings College London, UK
Short Talk: Asthma Exacerbations during Acute Respiratory Illness are Characterized by Distinct Expression Profiles of Immunoregulatory and Cellular Repair Genes in the Nasal Mucosa


Friday, January 11 | 8:00AM - 11:15AM
New Insights into the Pathogenesis of Lung Diseases
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 7 of 7
Gabriela Wlasiuk, University of Arizona, USA
Short Talk: Epigenetic Predictors of Childhood Asthma are Detectable in the Methylome at Birth


Friday, January 11 | 9:20AM - 9:40AM
Coffee Break
Room: Sweeney F, Main Level Breakouts


Friday, January 11 | 11:15AM - 1:00PM
Poster Setup
Room: Sweeney Ballroom F


Friday, January 11 | 11:15AM - 4:30PM
On Own for Lunch and Recreation


Friday, January 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Sweeney Ballroom F


Friday, January 11 | 4:30PM - 5:00PM
Coffee Available
Room: Sweeney Ballroom F


Friday, January 11 | 5:00PM - 7:00PM
Regulating the Type 2 Cytokines
Room: Sweeney Ballroom A-B

Speaker 1 of 5
* Thomas A. Wynn, Pfizer, USA

Friday, January 11 | 5:00PM - 7:00PM
Regulating the Type 2 Cytokines
Room: Sweeney Ballroom A-B

Speaker 2 of 5
Dirk E. Smith, Insight Bioconsulting, USA
The Role of IL-33 in Regulating Innate Airway Inflammation

Friday, January 11 | 5:00PM - 7:00PM
Regulating the Type 2 Cytokines
Room: Sweeney Ballroom A-B

Speaker 3 of 5
Steven F. Ziegler, Benaroya Research Institute, USA
TSLP in the Regulation of Type 2 Immunity

Friday, January 11 | 5:00PM - 7:00PM
Regulating the Type 2 Cytokines
Room: Sweeney Ballroom A-B

Speaker 4 of 5
Richard M. Maizels, University of Glasgow, UK
Modulation of the Host Immune Response by Parasitic Helminths

Friday, January 11 | 5:00PM - 7:00PM
Regulating the Type 2 Cytokines
Room: Sweeney Ballroom A-B

Speaker 5 of 5
Toshinori Nakayama, Chiba University, Japan
Short Talk: Sox4 Acts as a Downstream Target of TGFbeta and Suppresses GATA3-Induced Th2 Cell Differentiation

Friday, January 11 | 5:00PM - 7:00PM
Infectious Origins of Lung Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 5
* Jay K. Kolls, Tulane School of Medicine, USA


Friday, January 11 | 5:00PM - 7:00PM
Infectious Origins of Lung Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 5
James E. Gern, University of Wisconsin, USA
Virus Infections and Asthma Inception and Exacerbation


Friday, January 11 | 5:00PM - 7:00PM
Infectious Origins of Lung Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 5
Sebastian L. Johnston, Imperial College London, UK
Mechanisms of Rhinovirus-Induced Exacerbations in Asthma and COPD


Friday, January 11 | 5:00PM - 7:00PM
Infectious Origins of Lung Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 5
Michael J. Holtzman, Washington University in St. Louis, USA
Epithelial-Immune Cell Collaboration for Chronic Airway Disease


Friday, January 11 | 5:00PM - 7:00PM
Infectious Origins of Lung Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 5
Derek E. Byers, Washington University, USA
Short Talk: Predominant Role of IL-33 as the Upstream Inducer of IL-13-Mediated Chronic Airway Disease


Friday, January 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts


Friday, January 11 | 7:30PM - 10:00PM
Poster Session 1
Room: Sweeney Ballroom F


Saturday, January 12 | 7:00AM - 8:00AM
Breakfast
Room: Main Level Breakouts


Saturday, January 12 | 7:30AM - 8:00AM
Poster Setup
Room: Sweeney Ballroom F


Saturday, January 12 | 8:00AM - 5:00PM
Poster Viewing
Room: Sweeney Ballroom F


Saturday, January 12 | 8:00AM - 11:00AM
Innate Helper Cells in Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 6
* David Voehringer, University Hospital of Erlangen, Germany

Saturday, January 12 | 8:00AM - 11:00AM
Innate Helper Cells in Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 6
Andrew N. J. McKenzie, MRC Laboratory of Molecular Biology, UK
IL-25 and IL-33 Regulation of ILC2 in Protective Immunity and Allergy

Saturday, January 12 | 8:00AM - 11:00AM
Innate Helper Cells in Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 6
Hergen Spits, University of Amsterdam, Netherlands
The Spectrum of Human Innate Lymphoid Cells

Saturday, January 12 | 8:00AM - 11:00AM
Innate Helper Cells in Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 6
Richard M. Locksley, HHMI/University of California, San Francisco, USA
Function-Marking the Cells of Allergic Immunity

Saturday, January 12 | 8:00AM - 11:00AM
Innate Helper Cells in Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 6
Shigeo Koyasu, Keio University School of Medicine, Japan
Critical Role of GATA3 in the Differentiation and Function Natural Helper Cells, a Member of the Group 2 ILCs

Saturday, January 12 | 8:00AM - 11:00AM
Innate Helper Cells in Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 6
Laurel Monticelli, Weill Cornell Medicine, USA
Short Talk: Innate Lymphoid Cells Promote Airway Epithelial Repair through the Amphiregulin-EGFR Pathway

Saturday, January 12 | 9:20AM - 9:40AM
Coffee Break
Room: Sweeney F, Main Level Breakouts


Saturday, January 12 | 11:00AM - 12:00PM
Lunch
Room: Sweeney F, Main Level Breakouts


Saturday, January 12 | 12:00PM - 2:30PM
Poster Session 2
Room: Sweeney Ballroom F


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 8
* Clare M. Lloyd, Imperial College London, UK


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 8
Jennifer L. Ather, University of Vermont, USA
Serum Amyloid A Downregulates Bim Expression and Caspase-3 Activation in Serum-Starved Bone Marrow Derived Dendritic Cells and Induces Glucocorticoid Resistance in CD4+ T Cells


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 8
Sofia Tousa, Biomedical Research Foundation of the Academy of Athens, Greece
Activin-A-Induced Human Regulatory T Cells: Novel Controllers of Allergic Asthma


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 8
Elizabeth A. Jacobsen, Mayo Clinic, USA
Activated Pulmonary Eosinophils Are Necessary for Th2 Pulmonary Inflammation


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 8
Hiromasa Inoue, Kagoshima University, Japan
Role of Leukotriene B4 Receptor BLT2 in Allergic Airway Inflammation


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 6 of 8
Purvi Mehrotra, Indiana University School of Medicine, USA
PARP-14 and its Enzyme Activity Regulates Th2 Differentiation and Allergic Airway Disease


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 7 of 8
David J. Cousins, King's College London, UK
In vitro Differentiation and Transcriptome Profiling of Human Th9 Cells


Saturday, January 12 | 2:30PM - 4:30PM
Workshop 1: Molecular Regulation of Allergic Responses
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 8 of 8
Tao Liu, Brigham and Women’s Hospital, Harvard Medical School, USA
Deficiency of Inducible PGE2 is Sufficient to Cause Aspirin Sensitivity in the Setting of Pulmonary Inflammation


Saturday, January 12 | 4:30PM - 5:00PM
Coffee Available
Room: Sweeney Ballroom F


Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 1 of 7
* Richard M. Locksley, HHMI/University of California, San Francisco, USA

Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 2 of 7
K. Mark Ansel, University of California San Francisco, USA
MicroRNA Regulation of TFH and Th2 Cell Development

Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 3 of 7
Shane Crotty, La Jolla Institute for Immunology, USA
The Relationship between Th2 and Tfh Cells: Defining Characteristics of Tfh Cell Differentiation and Function

Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 4 of 7
Matthew D. Taylor, University of Edinburgh, UK
Short Talk: Th2 Cell Intrinsic Hypo-Responsiveness Determines Susceptibility to Helminth Infection via the PD-1/PD-L2 Pathway

Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 5 of 7
Fabienne Andris, Université Libre de Bruxelles, Belgium
Short Talk: The Capacity of Th2 Lymphocytes to Deliver B Cell Help Requires Expression of the Transcription Factor STAT3

Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 6 of 7
Nicholas van Panhuys, NIAID, National Institutes of Health, USA
Short Talk: TCR Strength of Signal is Upstream of and Dominates Over Cytokine Effects in Controlling CD4+ T Cell Polarization in Vivo

Saturday, January 12 | 5:00PM - 7:15PM
Adaptive Th2 and TFH Cells
Room: Sweeney Ballroom A-B

Speaker 7 of 7
Christopher D. C. Allen, University of California, San Francisco, USA
Short Talk: Regulation of IgE+ B Cell Responses Revealed by Novel Fluorescent Reporter Mice

Saturday, January 12 | 5:00PM - 7:00PM
Role of Th17 Cells in the Regulation of Lung Immunity
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 5
* Hergen Spits, University of Amsterdam, Netherlands


Saturday, January 12 | 5:00PM - 7:00PM
Role of Th17 Cells in the Regulation of Lung Immunity
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 5
Jay K. Kolls, Tulane School of Medicine, USA
Th17 Cells in the Regulation of Lung Immunity


Saturday, January 12 | 5:00PM - 7:00PM
Role of Th17 Cells in the Regulation of Lung Immunity
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 5
Susan V. Lynch, University of California, San Francisco, USA
Airway Microbiota and Lung Disease


Saturday, January 12 | 5:00PM - 7:00PM
Role of Th17 Cells in the Regulation of Lung Immunity
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 5
Marsha Wills-Karp, Johns Hopkins Bloomberg School of Public Health, USA
Colonization with Segmented Filamentous Bacteria Drives Severe Asthma through an IL-17A-Dependent Mechanism


Saturday, January 12 | 5:00PM - 7:00PM
Role of Th17 Cells in the Regulation of Lung Immunity
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 5
Saheli Chowdhury, Academic Medical Center, Netherlands
Short Talk: Exposure to IL-17 Reveals Defective mRNA Degradation by Bronchial Epithelial Cells in 70% of Patients with Asthma


Sunday, January 13 | 7:00AM - 8:00AM
Breakfast
Room: Main Level Breakouts


Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 1 of 7
* Hajime Karasuyama, Tokyo Medical and Dental University, Graduate School, Japan

Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 2 of 7
Wenjun Ouyang, Amgen, Inc., USA
Regulation and Function of IL-22 on Epithelial Cells

Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 3 of 7
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Commensal-Pathogen Interactions in Skin Immunity

Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 4 of 7
Sabine Eming, University of Cologne, Germany
Tissue Repair and Type 2 Immunity

Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 5 of 7
De' Broski R. Herbert, University of Pennsylvania, USA
Short Talk: Trefoil Factor 2 Initiates IL-33 Production for Non-Canonical Type 2 Immunity against Murine Hookworm Infection

Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 6 of 7
Soichiro Yoshikawa, Tokyo Medical and Dental University, Japan
Short Talk: Mechanisms Underlying the Recruitment, Accumulation and Activation of Basophils at Tick-Feeding Sites for Protective Immunity to Tick Re-Infestation

Sunday, January 13 | 8:00AM - 11:15AM
Commensals, Immunity and Epithelial Homeostasis
Room: Sweeney Ballroom A-B

Speaker 7 of 7
P'ng Loke, NYU School of Medicine, USA
Short Talk: Type 2 Immunity in Helminth Treatment for Inflammatory Bowel Diseases

Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 7
* Fernando D. Martinez, University of Arizona, USA


Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 7
Jeffrey A. Whitsett, Cincinnati Children's Hospital Medical Center, USA
Epigenetic and Genetic Regulation of Goblet Cell Metaplasia and Antiviral Innate Immunity by FOXA3


Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 7
Paul W. Noble, Cedars-Sinai Medical Center, USA
Matrix Regulation of Lung Injury, Inflammation and Repair


Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 7
Stephanie C. Eisenbarth, Yale University, USA
NOD-Like Receptors and the Regulation of Lung Inflammation


Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 7
Joanne L. Wright, University of British Columbia, Canada
Cigarette Smoke Induced COPD - Use of Animal Models


Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 6 of 7
Hesam Movassagh, University of Manitoba, Canada
Short Talk: Semaphorin 3E Inhibits Human Airway Smooth Muscle Cell Proliferation and Migration


Sunday, January 13 | 8:00AM - 11:15AM
Lung Development, Repair and Remodeling
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 7 of 7
Sejal Saglani, Imperial College London, UK
Short Talk: Interleukin-33 Promotes Airway Remodelling in Paediatric Severe Steroid Resistant Asthma


Sunday, January 13 | 9:20AM - 9:40AM
Coffee Break
Room: Sweeney F, Main Level Breakouts


Sunday, January 13 | 11:15AM - 1:00PM
Poster Setup
Room: Sweeney Ballroom F


Sunday, January 13 | 11:15AM - 4:30PM
On Own for Lunch and Recreation


Sunday, January 13 | 1:00PM - 10:00PM
Poster Viewing
Room: Sweeney Ballroom F


Sunday, January 13 | 4:30PM - 5:00PM
Coffee Available
Room: Sweeney Ballroom F


Sunday, January 13 | 5:00PM - 7:00PM
Myeloid Cells in Tissue Homeostasis
Room: Sweeney Ballroom A-B

Speaker 1 of 5
* Richard M. Maizels, University of Glasgow, UK

Sunday, January 13 | 5:00PM - 7:00PM
Myeloid Cells in Tissue Homeostasis
Room: Sweeney Ballroom A-B

Speaker 2 of 5
Judith E. Allen, University of Manchester, UK
Macrophages in Helminth Infection: Where Inflammation is Anti-Inflammatory

Sunday, January 13 | 5:00PM - 7:00PM
Myeloid Cells in Tissue Homeostasis
Room: Sweeney Ballroom A-B

Speaker 3 of 5
David Voehringer, University Hospital of Erlangen, Germany
Eosinophil and Basophil Responses to Allergens and Helminths

Sunday, January 13 | 5:00PM - 7:00PM
Myeloid Cells in Tissue Homeostasis
Room: Sweeney Ballroom A-B

Speaker 4 of 5
Hajime Karasuyama, Tokyo Medical and Dental University, Graduate School, Japan
Basophil as a Crucial Player in Acquired Immune Responses

Sunday, January 13 | 5:00PM - 7:00PM
Myeloid Cells in Tissue Homeostasis
Room: Sweeney Ballroom A-B

Speaker 5 of 5
Carla V. Rothlin, Yale University, USA
Short Talk: TAMing Type 2 Immunity

Sunday, January 13 | 5:00PM - 7:00PM
Mechanisms of Chronic Obstructive Pulmonary Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 5
* Sebastian L. Johnston, Imperial College London, UK


Sunday, January 13 | 5:00PM - 7:00PM
Mechanisms of Chronic Obstructive Pulmonary Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 5
Shyam Biswal, Johns Hopkins University, USA
Oxidative Stress Regulation of Lung Inflammation in COPD


Sunday, January 13 | 5:00PM - 7:00PM
Mechanisms of Chronic Obstructive Pulmonary Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 5
Augustine Choi, Harvard Medical School, USA
Regulation and Function of Autophagy in COPD


Sunday, January 13 | 5:00PM - 7:00PM
Mechanisms of Chronic Obstructive Pulmonary Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 5
Farrah Kheradmand, Baylor College of Medicine, USA
Autoreactive T Cells in The Pathophysiology of Human and Mouse Emphysema


Sunday, January 13 | 5:00PM - 7:00PM
Mechanisms of Chronic Obstructive Pulmonary Disease
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 5
Chandran Nagaraj, Ludwig Boltzmann Institute for Lung Vascular Research, Austria
Short Talk: p22phox Regulates House Dust Mite (HDM) Induced Allergic Airway Inflammation


Sunday, January 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts


Sunday, January 13 | 7:30PM - 10:00PM
Poster Session 3
Room: Sweeney Ballroom F


Monday, January 14 | 7:00AM - 8:00AM
Breakfast
Room: Main Level Breakouts


Monday, January 14 | 8:00AM - 11:00AM
Initiating Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 6
* Andrew N. J. McKenzie, MRC Laboratory of Molecular Biology, UK

Monday, January 14 | 8:00AM - 11:00AM
Initiating Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 6
Jean-Philippe Girard, Institute of Pharmacology and Structural Biology, France
IL-33 Processing and Activation by Inflammatory Proteases

Monday, January 14 | 8:00AM - 11:00AM
Initiating Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 6
Marco Idzko, University Hospital Freiburg, Germany
ATP and P2X Receptors in Type 2 Immunity

Monday, January 14 | 8:00AM - 11:00AM
Initiating Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 6
Jack A. Elias, Yale School of Medicine, USA
Chitinase-like Moieties in Lung Inflammation, Injury and Repair

Monday, January 14 | 8:00AM - 11:00AM
Initiating Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 6
Laura J. Simpson, Stanford University, USA
Short Talk: miRNA Expression in CD4 T Cells from Asthmatic Airways

Monday, January 14 | 8:00AM - 11:00AM
Initiating Type 2 Immunity (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 6
Takehiko Shibata, University of Michigan Medical School, USA
Short Talk: Gas6/TAM Signaling Differentially Modulates Chronic Fungal Asthma with the Expansion of Myeloid Regulatory Cell Subsets in Mice

Monday, January 14 | 9:00AM - 9:20AM
Coffee Break
Room: Sweeney F, Main Level Breakouts


Monday, January 14 | 11:00AM - 4:30PM
On Own for Lunch and Recreation


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 7
* Marsha Wills-Karp, Johns Hopkins Bloomberg School of Public Health, USA


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 7
Charles S. Dela Cruz, Yale University, USA
Cigarette Smoke Exposure Enhances Interleukin-15, NK and CD8 T Cell Responses during Influenza Virus Infection in Models of COPD


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 7
Sumit Ghosh, North Dakota State University, USA
Hyaluronic Acid Impacts B Lymphocyte Recruitment and Function in a Murine Fungal Allergic Asthma Model


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 7
Amali E. Samarasinghe, University of Tennessee Health Science Center, USA
Allergic Eosinophils Enhance Anti-Viral Defenses in a Murine Co-Morbidity Model of Asthma and Influenza


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 7
Tamlyn Peel, Imperial College London, UK
IL-17 Modulation of Rhinovirus-Induced Allergic Airways Disease


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 6 of 7
Lara Ravanetti, Academic Medical Center, Netherlands
Influenza-Induced Exacerbation in a Murine Chronic House Dust Mite (HDM) Asthma Model


Monday, January 14 | 2:30PM - 4:30PM
Workshop 2: Viral Infections and Exacerbations of Lung Disea
se
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 7 of 7
Kristen N. Kindrachuk, National Institutes of Health, USA
Muc5ac-Deficiency Exacerbates Bleomycin-Induced Airway Inflammation


Monday, January 14 | 4:30PM - 5:00PM
Coffee Available
Room: Sweeney Ballroom F


Monday, January 14 | 5:00PM - 7:15PM
Pathologic Syndromes
Room: Sweeney Ballroom A-B

Speaker 1 of 6
* Yasmine Belkaid, NIAID, National Institutes of Health, USA

Monday, January 14 | 5:00PM - 7:15PM
Pathologic Syndromes
Room: Sweeney Ballroom A-B

Speaker 2 of 6
Stuart G. Tangye, Garvan Institute of Medical Research, Australia
Lymphocyte Defects in Hyper-IgE Syndromes

Monday, January 14 | 5:00PM - 7:15PM
Pathologic Syndromes
Room: Sweeney Ballroom A-B

Speaker 3 of 6
Thomas A. Wynn, Pfizer, USA
Macrophages and Mucins in the Pathogenesis of Type 2 Immunity

Monday, January 14 | 5:00PM - 7:15PM
Pathologic Syndromes
Room: Sweeney Ballroom A-B

Speaker 4 of 6
Lawren C. Wu, Amgen Inc., USA
Therapeutic Targeting of IgE-Switched Cells in Asthma

Monday, January 14 | 5:00PM - 7:15PM
Pathologic Syndromes
Room: Sweeney Ballroom A-B

Speaker 5 of 6
Mark S. Wilson, Genentech, Inc., USA
Short Talk: miR-182 and miR-10a Are Key Regulators of Treg Specialisation and Stability during Th2 and Th1-Associated Inflammation

Monday, January 14 | 5:00PM - 7:15PM
Pathologic Syndromes
Room: Sweeney Ballroom A-B

Speaker 6 of 6
Adam Matson, University of Connecticut Health Center, USA
Short Talk: Maternal Allergy Is Associated with Surface-Bound IgE on Cord Blood Basophils

Monday, January 14 | 5:00PM - 7:00PM
Therapeutic Opportunities in Asthma and COPD
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 1 of 5
* Sally Wenzel-Morganroth, University of Pittsburgh, USA


Monday, January 14 | 5:00PM - 7:00PM
Therapeutic Opportunities in Asthma and COPD
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 2 of 5
Aili Lazaar, GlaxoSmithKline, USA
Challenges and Opportunities in COPD Drug Development


Monday, January 14 | 5:00PM - 7:00PM
Therapeutic Opportunities in Asthma and COPD
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 3 of 5
John G. Matthews, Genentech, Inc., USA
Treatment of Adult Asthmatics with the Anti-IL-13 Lebrikizumab


Monday, January 14 | 5:00PM - 7:00PM
Therapeutic Opportunities in Asthma and COPD
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 4 of 5
Alison L. Budelsky, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Blockade of IL-17RA in Asthma


Monday, January 14 | 5:00PM - 7:00PM
Therapeutic Opportunities in Asthma and COPD
This session is from Asthma and COPD
Room: Sweeney Ballroom C-E

Speaker 5 of 5
Sofie Lock Johansson, Institut for Molecular Medicine, Denmark
Short Talk: Microfibril Associated Protein 4 (MFAP4) Is Associated to Dyspnea and the Composite BODE Index in COPD


Monday, January 14 | 7:15PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts


Monday, January 14 | 8:00PM - 11:00PM
Entertainment
Room: Sweeney F, Main Level Breakouts


Monday, January 14 | 8:00PM - 11:00PM
Cash Bar
Room: Sweeney F, Main Level Breakouts


Tuesday, January 15 | 10:25AM - 10:25AM
Departure


*Session Chair.