Past Meeting | Keystone Symposia

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Vascular Biology and Human Diseases: From Molecular Pathways to Novel Therapeutics (2018J8)

Web Desc
Pulmonary Vascular Disease and Right Ventricular Dysfunction: Current Concepts and Future Therapies Organizer(s): Georg Hansmann, Stephen L. Archer and Margaret R. MacLean Date: September 10 - 15, 2012 Location: Portola Hotel & Spa, Monterey, CA, USA Sponsored by Bayer USA Foundation Summary of Meeting: Pulmonary arterial hypertension (PAH) is characterized by progressive obliteration of pulmonary arterioles leading to increased pulmonary vascular resistance, right heart failure and death in 40-60% of PAH patients five years after diagnosis. Proliferation, migration and resistance to apoptosis of vascular cells, as well as proliferative-inflammatory responses mediated by blood and fat cells, contribute to disease development. Despite more than 15 published randomized controlled trials (RCT) that demonstrated moderate effectiveness in improving exercise capacity, the approved PH drugs have not led to a cure. Hence, basic science and translational research focusing on the discovery of novel pathways in pulmonary vascular disease and right ventricular dysfunction, new drug targets, development of novel therapeutic paradigms, cell-based and pharmacotherapies, and their translation into RCTs, is urgently needed. This Keystone Symposia meeting will gather basic and clinical researchers working in the field of pulmonary vascular disease and right ventricular dysfunction. The focus is on basic science with strong impact on 1) our understanding of this fatal disease and 2) discoveries with great potential to be translated into clinical practice in the near future. Late-breaking clinical studies on novel PAH therapies will also be presented. Scholarship Deadline: June 7 2012 Discounted Abstract Deadline: June 7 2012 Abstract Deadline: June 21 2012 Discounted Registration Deadline: July 10 2012 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: American Heart Association's Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation American Heart Association's Council on Cardiovascular Disease in the Young $1 - $2,499 Pulmonary Circulation / Pulmonary Vascular Research Institute Pulmonary Hypertension Association We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Pulmonary Vascular Disease and Right Ventricular Dysfunction: Current Concepts and Future Therapies

Organizer(s): Georg Hansmann, Stephen L. Archer and Margaret R. MacLean

Date: September 10 - 15, 2012
Location: Portola Hotel & Spa, Monterey, CA, USA

Program


Monday, September 10 \| 4:00PM - 8:00PM Arrival and Registration Room: De Anza Foyer
Tuesday, September 11 \| 7:30AM - 8:30AM Breakfast Room: De Anza 1-2
Tuesday, September 11 \| 8:30AM - 9:30AM Welcome and Keynote Address Room: De Anza 3 Speaker 1 of 1 Stefanie Dimmeler, University of Frankfurt, Germany The Role of Stem Cells in Angiogenesis and Vascular Repair
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 1 of 7 * Duncan J. Stewart, Ottawa Hospital Research Institute, Canada
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 2 of 7 Stella Kourembanas, Children's Hospital Boston, Harvard Medical School, USA Role of Bone Marrow Stromal Cells in the Repair of Chronic Lung and Pulmonary Vascular Disease
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 3 of 7 Margaret R. MacLean, University of Glasgow, UK Serotonin and Estrogen in the Development of Pulmonary Arterial Hypertension
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 4 of 7 Paul M. Hassoun, Johns Hopkins University, USA Cross-Talk between Macrophages, Granulocytes and Vascular Cells in Pulmonary Vascular Diseases
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 5 of 7 Mark L. Ormiston, University of Cambridge, UK Short Talk: Impaired Natural Killer Cell Phenotype and Function in Pulmonary Arterial Hypertension and Animal Models of Disease
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 6 of 7 Izabela M. Chrobak, Boston University School of Medicine, USA Short Talk: Endothelial GATA6 Deficiency Promotes Pulmonary Arterial Hypertension
Tuesday, September 11 \| 9:30AM - 12:45PM The Role of Stem Cells, Progenitor and Differentiated Blood Cells in Pulmonary Vascular Disease and Repair Room: De Anza 3 Speaker 7 of 7 Duncan J. Stewart, Ottawa Hospital Research Institute, Canada Progenitor Cell Transplantation for Pulmonary Hypertension
Tuesday, September 11 \| 10:50AM - 11:10AM Coffee Break Room: De Anza Foyer
Tuesday, September 11 \| 12:45PM - 1:15PM Poster Setup Room: De Anza 1-2
Tuesday, September 11 \| 12:45PM - 2:30PM On Own for Lunch and Recreation
Tuesday, September 11 \| 1:15PM - 10:00PM Poster Viewing Room: De Anza 1-2
Tuesday, September 11 \| 2:30PM - 4:30PM Workshop 1: How to Translate Basic Research Findings into Im provement of Patient Care - The Role of Industry Room: De Anza 3 Speaker 1 of 5 Lynn Raju Punnoose, New York Presbyterian Weill Cornell, USA Lessons from Computerized Models on Right Ventricular Assist Devices in Pulmonary Arterial Hypertension
Tuesday, September 11 \| 2:30PM - 4:30PM Workshop 1: How to Translate Basic Research Findings into Im provement of Patient Care - The Role of Industry Room: De Anza 3 Speaker 2 of 5 Evelyn M. Horn, Weill Cornell, USA Support for the Failing RV in PAH
Tuesday, September 11 \| 2:30PM - 4:30PM Workshop 1: How to Translate Basic Research Findings into Im provement of Patient Care - The Role of Industry Room: De Anza 3 Speaker 3 of 5 Matthew Thomas, Novartis Institutes for BioMedical Research, UK Anti-Remodeling Therapies for Pulmonary Arterial Hypertension: Challenges for Drug Discovery
Tuesday, September 11 \| 2:30PM - 4:30PM Workshop 1: How to Translate Basic Research Findings into Im provement of Patient Care - The Role of Industry Room: De Anza 3 Speaker 4 of 5 * Stuart Rich, University of Chicago Medical Center, USA Panelist
Tuesday, September 11 \| 2:30PM - 4:30PM Workshop 1: How to Translate Basic Research Findings into Im provement of Patient Care - The Role of Industry Room: De Anza 3 Speaker 5 of 5 Timothy M. Moore, NHLBI, National Institutes of Health, USA Panelist
Tuesday, September 11 \| 4:30PM - 5:00PM Coffee Available Room: De Anza Foyer
Tuesday, September 11 \| 5:00PM - 7:00PM Growth Factors, TGF-beta/BMP Signaling and Pulmonary Vascula r Disease Room: De Anza 3 Speaker 1 of 6 * Georg Hansmann, Hannover Medical School, Germany
Tuesday, September 11 \| 5:00PM - 7:00PM Growth Factors, TGF-beta/BMP Signaling and Pulmonary Vascula r Disease Room: De Anza 3 Speaker 2 of 6 * Paul M. Hassoun, Johns Hopkins University, USA
Tuesday, September 11 \| 5:00PM - 7:00PM Growth Factors, TGF-beta/BMP Signaling and Pulmonary Vascula r Disease Room: De Anza 3 Speaker 3 of 6 Marc Humbert, Hôpital Antoine-Béclère, AP-HP, France New Insights into the Role of Cytokines, Chemokines and Growth Factors in Pulmonary Arterial Hypertension
Tuesday, September 11 \| 5:00PM - 7:00PM Growth Factors, TGF-beta/BMP Signaling and Pulmonary Vascula r Disease Room: De Anza 3 Speaker 4 of 6 Kenneth D. Bloch, Massachusetts General Hospital, USA Role of BMPR-2 and BMP Signaling in PAH - Lessons from Murine Models
Tuesday, September 11 \| 5:00PM - 7:00PM Growth Factors, TGF-beta/BMP Signaling and Pulmonary Vascula r Disease Room: De Anza 3 Speaker 5 of 6 Mark P. de Caestecker, Vanderbilt University, USA Short Talk: Chemical Chaperones Correct BMP Receptor Processing Errors in Hereditary Pulmonary Arterial Hypertension (HPAH)
Tuesday, September 11 \| 5:00PM - 7:00PM Growth Factors, TGF-beta/BMP Signaling and Pulmonary Vascula r Disease Room: De Anza 3 Speaker 6 of 6 Patricia A. Thistlethwaite, University of California, San Diego, USA Notch Signaling in Pulmonary Vascular Disease
Tuesday, September 11 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: De Anza 1-2
Tuesday, September 11 \| 7:30PM - 10:00PM Poster Session 1 Room: De Anza 1-2
Wednesday, September 12 \| 7:30AM - 8:30AM Breakfast Room: De Anza 1-2
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 1 of 7 * Stephen L. Archer, Queen's University, Canada
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 2 of 7 Peter F. Carmeliet, University of Leuven, VIB, Belgium Vascular Metabolomics
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 3 of 7 Georg Hansmann, Hannover Medical School, Germany The Protective Role of PPARgamma in Pulmonary Vascular Disease
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 4 of 7 Evangelos D. Michelakis, University of Alberta Hospital, Canada Mitochondrial Modulators in Pulmonary Arterial Hypertension
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 5 of 7 Yong-Hu Fang, University of Chicago, USA Short Talk: Inhibition of Glutaminolysis by 6-Diazo-5-Oxo-l-Norleucine (DON) Improves Right Ventricular Function in Monocrotaline Induced Pulmonary Hypertension
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 6 of 7 Kirsty M. Mair, University of Glasgow, UK Short Talk: Beneficial Effects of an Aromatase Inhibitor in Established Hypoxia-Induced Pulmonary Arterial Hypertension
Wednesday, September 12 \| 8:30AM - 11:45AM Metabolic Regulators in Pulmonary Vascular Disease Room: De Anza 3 Speaker 7 of 7 Nicholas Morrell, University of Cambridge, UK Generation of Patient-Derived Induced Pluripotent Stem Cells to Study BMP Receptor Dysfunction
Wednesday, September 12 \| 9:50AM - 10:10AM Coffee Break Room: De Anza Foyer
Wednesday, September 12 \| 11:45AM - 1:00PM Poster Setup Room: De Anza 1-2
Wednesday, September 12 \| 11:45AM - 2:30PM On Own for Lunch and Recreation
Wednesday, September 12 \| 1:00PM - 10:00PM Poster Viewing Room: De Anza 1-2
Wednesday, September 12 \| 2:30PM - 4:30PM Workshop 2: MicroRNAs and iPS Cells - Novel Tools and Target s in Cardiovascular Biology and Pulmonary Vascular Research Room: De Anza 3 Speaker 1 of 6 * Nicholas Morrell, University of Cambridge, UK
Wednesday, September 12 \| 2:30PM - 4:30PM Workshop 2: MicroRNAs and iPS Cells - Novel Tools and Target s in Cardiovascular Biology and Pulmonary Vascular Research Room: De Anza 3 Speaker 2 of 6 Jenny Grieve, University of Glasgow, UK The Role of miR-451 in the Development of Pulmonary Arterial Hypertension (PAH)
Wednesday, September 12 \| 2:30PM - 4:30PM Workshop 2: MicroRNAs and iPS Cells - Novel Tools and Target s in Cardiovascular Biology and Pulmonary Vascular Research Room: De Anza 3 Speaker 3 of 6 Kylie M. Drake, Cleveland Clinic, USA Treatment with Chloroquine Rescues Smad-Mediated microRNA Processing in Heritable Pulmonary Arterial Hypertension
Wednesday, September 12 \| 2:30PM - 4:30PM Workshop 2: MicroRNAs and iPS Cells - Novel Tools and Target s in Cardiovascular Biology and Pulmonary Vascular Research Room: De Anza 3 Speaker 4 of 6 Guillaume Margaillan, Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Canada miR-204 Accounts for HIF-1alpha Activation in Both Human and Experimental Pulmonary Arterial Hypertension
Wednesday, September 12 \| 2:30PM - 4:30PM Workshop 2: MicroRNAs and iPS Cells - Novel Tools and Target s in Cardiovascular Biology and Pulmonary Vascular Research Room: De Anza 3 Speaker 5 of 6 Allison R. Prewitt, Vanderbilt University, USA Caveolar Defects in Hereditary Pulmonary Arterial Hypertension (HPAH)
Wednesday, September 12 \| 2:30PM - 4:30PM Workshop 2: MicroRNAs and iPS Cells - Novel Tools and Target s in Cardiovascular Biology and Pulmonary Vascular Research Room: De Anza 3 Speaker 6 of 6 Edda Spiekerkoetter, Stanford University, USA FK506 - Identified in a High-Throughput Screen to Increase BMPR2 Signaling - Reverses Pulmonary Hypertension by Rescuing Endothelial Dysfunction
Wednesday, September 12 \| 4:30PM - 5:00PM Coffee Available Room: De Anza Foyer
Wednesday, September 12 \| 5:00PM - 7:00PM The Right Ventricle in Pulmonary Hypertension: Cardiomyocyte Function and Hemodynamic Performance Room: De Anza 3 Speaker 1 of 5 * Evangelos D. Michelakis, University of Alberta Hospital, Canada
Wednesday, September 12 \| 5:00PM - 7:00PM The Right Ventricle in Pulmonary Hypertension: Cardiomyocyte Function and Hemodynamic Performance Room: De Anza 3 Speaker 2 of 5 Stephen L. Archer, Queen's University, Canada Right Ventricular Function and Metabolism in Pulmonary Hypertension: Mechanisms and Potential Metabolic Therapies
Wednesday, September 12 \| 5:00PM - 7:00PM The Right Ventricle in Pulmonary Hypertension: Cardiomyocyte Function and Hemodynamic Performance Room: De Anza 3 Speaker 3 of 5 Titus Kühne, German Heart Institute, Germany Assessment of Right Ventricular Function by MRI and Pressure-Volume Loops
Wednesday, September 12 \| 5:00PM - 7:00PM The Right Ventricle in Pulmonary Hypertension: Cardiomyocyte Function and Hemodynamic Performance Room: De Anza 3 Speaker 4 of 5 Andrew Redington, Hospital for Sick Children, Canada Interactions between Right and Left Ventricle in Pulmonary Hypertension
Wednesday, September 12 \| 5:00PM - 7:00PM The Right Ventricle in Pulmonary Hypertension: Cardiomyocyte Function and Hemodynamic Performance Room: De Anza 3 Speaker 5 of 5 Simon C. Rowan, University College Dublin, Republic of Ireland, Ireland Short Talk: Haploinsufficiency of Gremlin Augments NOS Expression and Activity in the Hypoxic Pulmonary Circulation
Wednesday, September 12 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: De Anza 1-2
Wednesday, September 12 \| 7:30PM - 10:00PM Poster Session 2 Room: De Anza 1-2
Thursday, September 13 \| 7:30AM - 8:30AM Breakfast Room: De Anza 1-2
Thursday, September 13 \| 8:30AM - 11:30AM MicroRNAs in Proliferative Vascular Disease Room: De Anza 3 Speaker 1 of 6 * Margaret R. MacLean, University of Glasgow, UK
Thursday, September 13 \| 8:30AM - 11:30AM MicroRNAs in Proliferative Vascular Disease Room: De Anza 3 Speaker 2 of 6 Andrew H. Baker, University of Edinburgh, UK MicroRNAs in Vascular Remodeling and PAH
Thursday, September 13 \| 8:30AM - 11:30AM MicroRNAs in Proliferative Vascular Disease Room: De Anza 3 Speaker 3 of 6 Norbert F. Voelkel, Virginia Commonwealth University, USA Histone Deactylation in the Right Ventricle and Pulmonary Vasculature
Thursday, September 13 \| 8:30AM - 11:30AM MicroRNAs in Proliferative Vascular Disease Room: De Anza 3 Speaker 4 of 6 Sebastien Bonnet, Université Laval, Canada Role for DNA Repair and miRNAs in the Epigenetics Abnormalities Seen in PAH
Thursday, September 13 \| 8:30AM - 11:30AM MicroRNAs in Proliferative Vascular Disease Room: De Anza 3 Speaker 5 of 6 Pawel Stankiewicz, Baylor College of Medicine, USA Short Talk: Deletions of lncRNAs Cause a Lethal Lung Developmental Disorder Showing Parent of Origin Effects
Thursday, September 13 \| 8:30AM - 11:30AM MicroRNAs in Proliferative Vascular Disease Room: De Anza 3 Speaker 6 of 6 Roxane Paulin, University of Alberta, Canada Short Talk: A MicroRNA Signature Characterizing the Transition from a Compensated to a Decompensated Right Ventricle
Thursday, September 13 \| 9:50AM - 10:10AM Coffee Break Room: De Anza Foyer
Thursday, September 13 \| 11:30AM - 2:30PM On Own for Lunch and Recreation
Thursday, September 13 \| 2:30PM - 3:00PM Coffee Available Room: De Anza Foyer
Thursday, September 13 \| 3:00PM - 5:00PM Innovative Clinical PAH Trials Room: De Anza 3 Speaker 1 of 6 Evangelos D. Michelakis, University of Alberta Hospital, Canada and
Thursday, September 13 \| 3:00PM - 5:00PM Innovative Clinical PAH Trials Room: De Anza 3 Speaker 2 of 6 Martin R. Wilkins, Imperial College London, UK Dichloroacetate (DCA) for the Treatment of Pulmonary Hypertension
Thursday, September 13 \| 3:00PM - 5:00PM Innovative Clinical PAH Trials Room: De Anza 3 Speaker 3 of 6 Stuart Rich, University of Chicago Medical Center, USA Clinical Trial Design Issues in Pulmonary Hypertension
Thursday, September 13 \| 3:00PM - 5:00PM Innovative Clinical PAH Trials Room: De Anza 3 Speaker 4 of 6 Mark R. Nicolls, Stanford University School of Medicine, USA Targeting Immunity in the Treatment of PAH: The Rituximab SSc-PAH Trial
Thursday, September 13 \| 3:00PM - 5:00PM Innovative Clinical PAH Trials Room: De Anza 3 Speaker 5 of 6 * Marc Humbert, Hôpital Antoine-Béclère, AP-HP, France Panelist
Thursday, September 13 \| 3:00PM - 5:00PM Innovative Clinical PAH Trials Room: De Anza 3 Speaker 6 of 6 Duncan J. Stewart, Ottawa Hospital Research Institute, Canada Panelist
Thursday, September 13 \| 5:00PM - 6:00PM Social Hour with Lite Bites Room: De Anza 1-2
Thursday, September 13 \| 6:00PM - 6:00PM On Own for Dinner
Friday, September 14 \| 7:30AM - 8:30AM Breakfast Room: De Anza 1-2
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 1 of 7 * Stella Kourembanas, Children's Hospital Boston, Harvard Medical School, USA
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 2 of 7 * Mark A. Krasnow, Stanford University School of Medicine, USA Building the Pulmonary Artery
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 3 of 7 Bernard Thébaud, Ottawa Hospital Research Institute, Canada Progenitor Cells in Diaphragmatic Hernia, Pulmonary Hypoplasia and PH Associated with Neonatal Lung Injury
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 4 of 7 Jane A. Mitchell, Imperial College London, UK The Role of PPAR beta/delta in Pulmonary Hypertension
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 5 of 7 Lei Zhou, Texas Heart Institute, USA Short Talk: ELPC-Based Prostacyclin Gene Therapy Rescues Monocrotaline-Induced Pulmonary Arterial Hypertension
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 6 of 7 Stuart W. Jamieson, University of California, San Diego Medical Center, USA Pulmonary Hypertension as a Result of Chronic Pulmonary Embolism-Surgical Treatment
Friday, September 14 \| 8:30AM - 11:45AM Pulmonary Hypertension in Parenchymal Lung and Thromboemboli c Diseases Room: De Anza 3 Speaker 7 of 7 Aiko Ogawa, National Hospital Organization Okayama Medical Center, Japan Short Talk: Thrombin Induces Proliferation of Cells from Patients with Chronic Thromboembolic Pulmonary Hypertension via Akt/mTOR Pathway
Friday, September 14 \| 9:50AM - 10:10AM Coffee Break Room: De Anza Foyer
Friday, September 14 \| 11:45AM - 2:30PM On Own for Lunch and Recreation
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 1 of 7 * Martin R. Wilkins, Imperial College London, UK
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 2 of 7 Alex M.K. Rothman, University of Sheffield, UK Whole Blood miRNA Expression in Pulmonary Arterial Hypertension (PAH) Reveals Down-Regulation of MicroRNA-140-5p in Idiopathic and Scleroderma-Associated PAH
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 3 of 7 Jessie R. Lavoie, Ottawa Hospital Research Institute, Canada Proteomic Analysis Identifies Translationally Controlled Tumor Protein (TCTP) as a Potential Novel Mediator of Occlusive Vascular Remodeling in Pulmonary Arterial Hypertension
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 4 of 7 Ferhaan Ahmad, University of Iowa, USA Pulmonary Arterial Hypertension Induces Gene Expression Changes in the Right Ventricle in Advance of Right Ventricular Failure that Are More Severe in Female Rats
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 5 of 7 Giovanna Frazziano, Ri.MED Foundation/ISMETT, Italy Nox-Derived ROS Is Increased in a Model of Pressure Overload in Mouse Right Ventricle
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 6 of 7 Elena A. Goncharova, University of Pennsylvania, USA mTORC2 Coordinates Energy Metabolism, Proliferation and Survival of Vascular Smooth Muscle Cells in Idiopathic PAH
Friday, September 14 \| 2:30PM - 4:30PM Workshop 3: Vascular Metabolomics and Proteomics: Where Are the Novel Biomarkers for Pulmonary Vascular Diseases? Room: De Anza 3 Speaker 7 of 7 Kathryn N. Farrow, Northwestern University, USA Disruption of cGMP Signaling in Small Pulmonary Arteries Occurs Rapidly and Persists in BPD Mice with Pulmonary Hypertension
Friday, September 14 \| 4:30PM - 5:00PM Coffee Available Room: De Anza Foyer
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 1 of 7 * Georg Hansmann, Hannover Medical School, Germany
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 2 of 7 * Margaret R. MacLean, University of Glasgow, UK
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 3 of 7 * Stephen L. Archer, Queen's University, Canada
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 4 of 7 Karim Christian El Kasmi, Boehringer Ingelheim Pharma, Germany Chronic Inflammation, Autoimmunity and Epigenetics: A Critical Drug-Targetable Triumvirate in Pulmonary Hypertension
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 5 of 7 Martin R. Wilkins, Imperial College London, UK Novel Biomarkers for Pulmonary Vascular Disease and Right Ventricular Dysfunction
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 6 of 7 Stephen L. Archer, Queen's University, Canada
Friday, September 14 \| 5:00PM - 7:00PM Pulmonary Arterial Hypertension - Current Concepts and Futur e Therapies Room: De Anza 3 Speaker 7 of 7 Timothy M. Moore, NHLBI, National Institutes of Health, USA Panelist
Friday, September 14 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: De Anza 1-2
Friday, September 14 \| 8:00PM - 11:00PM Entertainment Room: De Anza 1-2
Friday, September 14 \| 8:00PM - 11:00PM Cash Bar Room: De Anza 1-2
Saturday, September 15 \| 10:25AM - 10:25AM Departure *Session Chair.