Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
B Cell Renaissance: Epigenetics, Regulation and Immunotherapy (2020X1)
B Cells: Mechanisms in Immunity and Autoimmunity (2018E4)
B Cells and T Follicular Helper Cells - Controlling Long-Lived Immunity (2017D2)
B Cells at the Intersection of Innate and Adaptive Immunity (2016E3)
The Golden Anniversary of B Cell Discovery (2015X6)
Biology of B Cell Responses (2014Q4)

Web Desc
B Cell Development and Function joint with HIV Vaccines Organizer(s): Max D. Cooper, Andrea Cerutti and Carola G. Vinuesa Date: February 10 - 15, 2013 Location: Keystone Resort, Keystone, CO, USA Sponsored by Onyx Pharmaceuticals, Inc. For important information on the coronavirus, please click here Summary of Meeting: This meeting will provide an overview of the most recent advances in the biology of B cells. In addition to covering the function of B cells under steady-state conditions and infection, the meeting will provide an update on the alterations of B cells in autoimmunity, leukemia and lymphoma. The mechanisms by which B cells crosstalk with different components of the innate and adaptive immune systems and the contribution of distinct B cell subsets to systemic and mucosal immunity remain unclear, particularly in humans. This meeting has the following specific aims: 1) to define the factors involved in B cell lineage specification and reprogramming; 2) to elucidate the evolution and mechanisms of the processes underpinning antibody gene diversification; 3) to better understand the B cell pathways required for systemic and mucosal antibody responses against T cell-dependent and T cell-independent antigens; 4) to clarify the mechanisms by which antibodies provide protection against HIV; 5) to broaden our understanding of the molecular alterations associated with autoimmune and neoplastic B cell disorders; and 6) to provide an interactive forum to involve early stage investigators and highlight their discoveries. By addressing these problems, this meeting will not only generate new knowledge on the biology of B cells in health and disease states, but it will also provide a framework for investigators and clinicians to generate new ideas, initiate new collaborations, and eventually introduce changes in clinical practice. In addition, this meeting will provide a unique opportunity to “take a closer look” at B cells by linking experts in B cell biology with experts in stem cell biology, comparative immunology, molecular biology, and in vivo imaging. Additional opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on HIV Vaccines, which will share a keynote session and two plenary sessions with this meeting. Scholarship Deadline: October 10 2012 Discounted Abstract Deadline: October 10 2012 Abstract Deadline: November 12 2012 Discounted Registration Deadline: December 10 2012 Abstacts when book is in proofing process Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI104097-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

B Cell Development and Function

joint with HIV Vaccines

Organizer(s): Max D. Cooper, Andrea Cerutti and Carola G. Vinuesa

Date: February 10 - 15, 2013
Location: Keystone Resort, Keystone, CO, USA

Program


Sunday, February 10 \| 3:00PM - 7:30PM Arrival and Registration Room: Longs Peak Foyer
Sunday, February 10 \| 6:15PM - 7:15PM Refreshments Room: Longs Peak Foyer
Sunday, February 10 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Columbine Ballroom Speaker 1 of 4 * Max D. Cooper, Emory University, USA
Sunday, February 10 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Columbine Ballroom Speaker 2 of 4 * Georgia D. Tomaras, Duke University Medical Center, USA
Sunday, February 10 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Columbine Ballroom Speaker 3 of 4 Myron S. Cohen, University of North Carolina at Chapel Hill, USA HIV Prevention 2013: Preparing for a Vaccine
Sunday, February 10 \| 7:15PM - 9:30PM Welcome and Keynote Session (Joint) Room: Columbine Ballroom Speaker 4 of 4 Michel C. Nussenzweig, HHMI/Rockefeller University, USA The Human Antibody Response to HIV
Monday, February 11 \| 7:00AM - 8:00AM Breakfast Room: Colorado Rockies Ballroom
Monday, February 11 \| 8:00AM - 11:15AM B Cell Genesis Room: Longs/Grays Peaks Speaker 1 of 6 * Max D. Cooper, Emory University, USA Evolution of Adaptive Immunity in Vertebrates
Monday, February 11 \| 8:00AM - 11:15AM B Cell Genesis Room: Longs/Grays Peaks Speaker 2 of 6 Rudolf Grosschedl, Max Planck Institute of Immunobiology and Epigenetics, Germany Mechanisms Underlying Transcriptional Control of B Cell Differentiation
Monday, February 11 \| 8:00AM - 11:15AM B Cell Genesis Room: Longs/Grays Peaks Speaker 3 of 6 Tasuku Honjo, Kyoto University Graduate School of Medicine, Japan Acquired Immunity, Genome Instability, and Cancer
Monday, February 11 \| 8:00AM - 11:15AM B Cell Genesis Room: Longs/Grays Peaks Speaker 4 of 6 Frederick W. Alt, Boston Children's Hospital, USA V(D)J Recombination, IgH Class Switch Recombination, and Genomic Instability
Monday, February 11 \| 8:00AM - 11:15AM B Cell Genesis Room: Longs/Grays Peaks Speaker 5 of 6 Bao Q. Vuong, City College of New York, CUNY, USA Short Talk: A DNA Double Strand Break and Phosphorylation-Dependent Positive Feedback Loop Promotes Class Switch Recombination
Monday, February 11 \| 8:00AM - 11:15AM B Cell Genesis Room: Longs/Grays Peaks Speaker 6 of 6 Patricia J. Gearhart, NIA, National Institutes of Health, USA Short Talk: Transcriptional Stalling of RNA Polymerase II Gives AID Access to Immunoglobulin Variable Genes
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 7 * James A. Hoxie, University of Pennsylvania, USA
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 7 David H. O'Connor, University of Wisconsin-Madison, USA Understanding SIV Control in Macaques with Restricted Genetic Diversity
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 7 Genoveffa Franchini, NCI, National Institutes of Health, USA Innate and Adaptive Immune Correlate of Protection Against SIVmac251
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 7 Kevin O. Saunders, Duke University, USA Short Talk: Lasting Protection Against SHIV by VRC01 Protein Immunoprophylaxis in Indian Rhesus Macaques
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 7 * Jeffrey D. Lifson, Leidos Biomedical Research, Inc., USA Recent Developments in Non-human Primate Models for AIDS-related Vaccine Studies
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 7 Sallie R. Permar, Duke University Medical Center, USA Immune Protection against Postnatal HIV-1/SIV Transmission
Monday, February 11 \| 8:00AM - 11:15AM Protective Responses in Animal Models This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 7 David B. Weiner, Wistar Institute, USA Short Talk: Non-Human Primate Challenge Model to Study the Role of Serum and Vaginal IgA in Acquisition of Infection
Monday, February 11 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Monday, February 11 \| 10:00AM - 10:00AM On Own for Lunch and Recreation
Monday, February 11 \| 11:15AM - 12:45PM Hands On Computer Workshop on Los Alamos Sequence Database a nd Tools This session is from HIV Vaccines Room: Castle Peaks Maximum attendance: 60. Interested participants must sign up at the meeting on a first-come, first-serve basis. Instructor: Brian Foley, Los Alamos National Laboratory
Monday, February 11 \| 11:15AM - 1:00PM Poster Setup Room: Colorado Rockies Ballroom
Monday, February 11 \| 1:00PM - 10:00PM Poster Viewing Room: Colorado Rockies Ballroom
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 1 of 8 * † David J. Rawlings, University of Washington, Seattle Children's Hospital Research Institute, USA
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 2 of 8 Anupam Banerjee, University of Pennsylvania, USA Transcriptional Repression of Gata3 Is Essential for Early B Cell Commitment
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 3 of 8 Matteo Villa, MPI Immunobiology and Epigenetics, Germany The Role of Aryl Hydrocarbon Receptor in B Cell-Mediated Immunity
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 4 of 8 * Mary Ellen Conley, University of Tennessee College of Medicine, USA A Dominant Negative Mutation in the Transcription Factor E2A in Patients with Agammaglobulinemia
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 5 of 8 Stéphane J. C. Mancini, INSERM, France The Development of the Pro-B and Pre-B Cell Subsets Depends on Distinct Bone Marrow Stromal Cell Niches
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 6 of 8 Thomas Beck, Yale University, USA Molecular Mechanisms of Developing B Cell Egress from the Bone Marrow
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 7 of 8 Andre Limnander, Regeneron, USA Unraveling the Molecular Mechanisms of Developmental Checkpoints during B Cell Selection in the Bone Marrow
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: B Cell Development and Signaling Room: Longs/Gray Peaks Speaker 8 of 8 Marc Schwartz, Dana Farber Cancer Institute / Broad Institute, USA The Role of CD40 in Peripheral B Cell Development
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 9 * George K. Lewis, University of Maryland, USA
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 9 * Mark Connors, NIAID, National Institutes of Health, USA
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 9 James E. Voss, The Scripps Research Institute, USA SIV Vaccine Induces Local AntibodyProduction and Delivery Correlate with Protection in Female Reproductive Tract Protection.
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 9 Justin Pollara, Duke University, USA Synergy between C1 Conformational and Anti-V2 Monoclonal Antibodies for Cell Surface Binding and ADCC
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 9 Chiara Orlandi, University of Maryland, USA Potent ADCC Mediated by Human Monoclonal Antibodies (mAbs) Against Multiple Conserved Epitopes of HIV-Env
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 9 Ross W. Lindsay, Stemline Therapeutics, USA An Inactivated Viral Vaccine that Displays Conformationally Intact HIV-1 Envelope Trimers Elicits Neutralizing Antibodies
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 9 Andrew McGuire, Fred Hutchinson Cancer Research Center, USA Engaging of the Germline BCRs of Anti-HIV bNAbs with Modified Recombinant Env Immunogens
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 8 of 9 Andrew B. Ward, The Scripps Research Institute, USA Evaluating HIV Envelope Trimers as Structural Scaffolds and Immunogens
Monday, February 11 \| 2:30PM - 4:30PM Workshop 1: Antibody Effector Functions and Env Based Immuno gen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 9 of 9 Joseph R. Francica, Vaccine Research Center, National Institutes of Health, USA Genetic Assessment of B Cell Responses in NHP following HIV Env Immunization
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 1 of 8 * Patrick C. Wilson, University of Chicago, USA
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 2 of 8 * George Georgiou, University of Texas at Austin, USA
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 3 of 8 Robert W. Maul, NIA, National Institutes of Health, USA B Cell Receptor Stimulation Induces Uracil DNA Glycosylase and Inhibits Class Switch Recombination
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 4 of 8 Leng-Siew Yeap, Boston Children's Hospital, USA Mechanisms by which DNA Sequences Influence Activation Induced Cytidine Deaminase (AID) Activity in Somatic Hypermutation and Class Switch Recombination
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 5 of 8 Jeroen E. Guikema, Academic Medical Center Amsterdam, Netherlands Genome-Wide Analysis of RAG-Induced DNA Breaks in Developing B Cells
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 6 of 8 Stephen P. Methot, Institut de Recherches Cliniques de Montreal, Canada Differentiating the Roles of Activation Induced Deaminase Cytoplasmic Retention and Nuclear Export
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 7 of 8 Menno C. van Zelm, Monash University, Australia B Cell Antigen Receptor and CD40 Signaling Together Direct Human Antibody Maturation and Selection
Monday, February 11 \| 2:30PM - 4:30PM Workshop 2: Molecular Basis of Antibody Diversification Room: Castle Peaks Speaker 8 of 8 Maria A. Curotto de Lafaille, New York University School of Medicine, USA How the Failure-to-Thrive of IgE Germinal Centers Cells Paves the Way for the Unique Role of Sequential Switching in Generating IgE Plasma Cells
Monday, February 11 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Monday, February 11 \| 5:00PM - 7:15PM Early Events in B Cell Activation Room: Longs/Grays Peaks Speaker 1 of 5 * Facundo D. Batista, Massachusetts Institute of Technology and Harvard University, USA Dynamic Imaging of Lymphocyte Activation - From Single Molecule to Living Tissue
Monday, February 11 \| 5:00PM - 7:15PM Early Events in B Cell Activation Room: Longs/Grays Peaks Speaker 2 of 5 Michael Reth, Albert-Ludwigs University Freiburg, Germany Role of Protein Islands for the Activation of B Cells
Monday, February 11 \| 5:00PM - 7:15PM Early Events in B Cell Activation Room: Longs/Grays Peaks Speaker 3 of 5 Susan K. Pierce, NIAID, National Institutes of Health, USA How B Cells Remember
Monday, February 11 \| 5:00PM - 7:15PM Early Events in B Cell Activation Room: Longs/Grays Peaks Speaker 4 of 5 Michael C. Carroll, Boston Children's Hospital, Harvard Medical School, USA Short Talk: Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Binding and Activation
Monday, February 11 \| 5:00PM - 7:15PM Early Events in B Cell Activation Room: Longs/Grays Peaks Speaker 5 of 5 Victor L.J. Tybulewicz, Francis Crick Institute, UK Short Talk: The B Cell Antigen Receptor Transduces Signals from the BAFF Receptor Required for B Cell Survival
Monday, February 11 \| 5:00PM - 7:00PM Potentially Protective Responses in Human Clinical Trials This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 6 * Georgia D. Tomaras, Duke University Medical Center, USA
Monday, February 11 \| 5:00PM - 7:00PM Potentially Protective Responses in Human Clinical Trials This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 6 * Lawrence Corey, Fred Hutchinson Cancer Research Center, USA
Monday, February 11 \| 5:00PM - 7:00PM Potentially Protective Responses in Human Clinical Trials This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 6 Merlin L. Robb, Walter Reed Army Institute of Research, USA Military HIV Research Program Clinical Studies and the Search for Correlates
Monday, February 11 \| 5:00PM - 7:00PM Potentially Protective Responses in Human Clinical Trials This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 6 Glenda E. Gray, South African Medical Research Council, South Africa Efficacy Trials in South Africa: Factors Affecting Vaccine Induced Immune Response in HIV Clinical Trials
Monday, February 11 \| 5:00PM - 7:00PM Potentially Protective Responses in Human Clinical Trials This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 6 Barney S. Graham, NIAID, National Institutes of Health, USA Active and Passive Immunity Against HIV
Monday, February 11 \| 5:00PM - 7:00PM Potentially Protective Responses in Human Clinical Trials This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 6 Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA Short Talk: RV144-Induced V1V2 Antibodies Reactive with Multiple Subtypes Correlated with Decreased Risk of HIV-1 Infection
Monday, February 11 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Colorado Rockies Ballroom
Monday, February 11 \| 7:30PM - 10:00PM Poster Session 1 Room: Colorado Rockies Ballroom
Tuesday, February 12 \| 7:00AM - 8:00AM Breakfast Room: Colorado Rockies Ballroom
Tuesday, February 12 \| 8:00AM - 11:15AM B Cell Evolution and Repertoire Selection Room: Longs/Grays Peaks Speaker 1 of 6 * Ana Cumano, Pasteur Institute, France Lineage Commitment in Fetal Hematopoiesis
Tuesday, February 12 \| 8:00AM - 11:15AM B Cell Evolution and Repertoire Selection Room: Longs/Grays Peaks Speaker 2 of 6 Michael S. Neuberger, Medical Research Council, UK The AID/APOBEC Family of DNA Deaminases: Balancing Immunity versus Cancer
Tuesday, February 12 \| 8:00AM - 11:15AM B Cell Evolution and Repertoire Selection Room: Longs/Grays Peaks Speaker 3 of 6 Garnett H. Kelsoe, Duke University and Medical Center, USA Genetic Control of the First Tolerance Checkpoint in B Cells
Tuesday, February 12 \| 8:00AM - 11:15AM B Cell Evolution and Repertoire Selection Room: Longs/Grays Peaks Speaker 4 of 6 Hedda Wardemann, German Cancer Research Center, Germany An Atlas of the Murine B Cell Repertoire: From Immunoglobulin Sequence to B Cell Differentiation State and Histo-Anatomical Localization
Tuesday, February 12 \| 8:00AM - 11:15AM B Cell Evolution and Repertoire Selection Room: Longs/Grays Peaks Speaker 5 of 6 Ziv Shulman, Weizmann Institute, Israel Short Talk: T Follicular Helper Cell Dynamics in Germinal Centers
Tuesday, February 12 \| 8:00AM - 11:15AM B Cell Evolution and Repertoire Selection Room: Longs/Grays Peaks Speaker 6 of 6 Christopher D. C. Allen, University of California, San Francisco, USA Short Talk: IgE-Expressing B Cells Are Restrained by an Intrinsic Cell Fate Predisposition
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 7 * Barbara L. Shacklett, University of California, Davis, USA
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 7 * Daniel C. Douek, NIAID, National Institutes of Health, USA
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 7 Ronald N. Germain, NIAID, National Institutes of Health, USA Imaging Immune Cell Dynamics and Function
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 7 Jacob D. Estes, Oregon Health and Science University, USA Early Events following SIV Mucosal Challenge
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 7 Shane Crotty, La Jolla Institute for Immunology, USA Designing Vaccines: The Role of CD4 follicular T-helper Cells
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 7 Mario Roederer, NIAID, National Institutes of Health, USA Single Cell Transcriptomics: Measuring Quality and Quantity
Tuesday, February 12 \| 8:00AM - 11:00AM Quality of Immune Response (Immune Geography and Memory) This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 7 Qingsheng Li, University of Nebraska Center for Virology, USA Short Talk: Distribution and Dissemination of Transmitted SIV Viruses in the Early Infection of Rhesus macaques via Anal/Rectal Route
Tuesday, February 12 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Tuesday, February 12 \| 10:00AM - 10:00AM On Own for Lunch and Recreation
Tuesday, February 12 \| 11:00AM - 12:30PM Hands On Computer Workshop on Los Alamos Immunology Database and Tools This session is from HIV Vaccines Room: Castle Peaks Maximum attendance: 60. Interested participants must sign up at the meeting on a first-come, first-serve basis. Instructor: Brian Foley, Los Alamos National Laboratory
Tuesday, February 12 \| 11:15AM - 1:00PM Poster Setup Room: Colorado Rockies Ballroom
Tuesday, February 12 \| 1:00PM - 10:00PM Poster Viewing Room: Colorado Rockies Ballroom
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 1 of 10 * Leonidas Stamatatos, Fred Hutchinson Cancer Research Center, USA
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 2 of 10 * Jonathan W. Yewdell, NIAID, National Institutes of Health, USA
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 3 of 10 David Nemazee, The Scripps Research Institute, USA Knock-In Mice Expressing Broadly Neutralizing HIV Antibodies b12 and 4E10
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 4 of 10 Katherine Nicholas, Vanderbilt University Medical Center, USA The Effect of Chronic HIV-1 Infection on pTFH Cells
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 5 of 10 Josiane Chagnon-Choquet, Université de Montréal, Canada Maintenance of Breg Capacity and Increased LT-alpha Expression by First Line MZ-Like B Cells Is Associated with Control of HIV Disease Progression
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 6 of 10 Adam K. Wheatley, University of Melbourne, Australia Prime-Boost Vaccination Against Influenza H5N1 Elicits the Expansion of Potentially Neutralizing H5/H1 Cross-Reactive Memory B Cells
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 7 of 10 Hongyan Liao, University of Nebraska Medical Center, USA Dominant Production of Polyreactive Antibodies by Circulating Plasmablasts in HIV-Infected Individuals
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 8 of 10 Sarah F. Andrews, National Institutes of Health, USA Adaptibility of the Human Influenza-specific Antibody Response
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 9 of 10 Sean P. McBurney, Oregon Health Sciences University, USA Elicitation of MPER-Specific Neutralizing Antibodies following Vaccination with an MPER-Targeted Vaccine Strategy
Tuesday, February 12 \| 2:30PM - 4:30PM Joint Workshop: B Cell Responses to Vaccines and HIV Room: Longs/Grays Peaks Speaker 10 of 10 John B. Schell, Yale School of Medicine, USA An Env-Only Vaccine Does Not Provide Sterilizing Protection of Rhesus macaques Against High-Dose SIVsmE660 Challenge
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Mucosal B Cell Responses Room: Quandary Peak Speaker 1 of 6 * Sidonia Fagarasan, RIKEN Research Center for Allergy and Immunology, Japan
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Mucosal B Cell Responses Room: Quandary Peak Speaker 2 of 6 Samuel K. Lai, University of North Carolina at Chapel Hill, USA Mucosal Immunity Mediated by Antibody-Mucin Crosslinking
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Mucosal B Cell Responses Room: Quandary Peak Speaker 3 of 6 Georg F. Weber, University Hospital Erlangen, Germany Protective Function of Pleural B Cells in Pneumonia
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Mucosal B Cell Responses Room: Quandary Peak Speaker 4 of 6 Mats Bemark, Gothenburg University, Sweden Oral Immunization Induces Long-Lived Intestinal and Bone Marrow Plasma Cells and Memory B Cells Destined for Mucosal Homing
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Mucosal B Cell Responses Room: Quandary Peak Speaker 5 of 6 Øyvind Steinsbø, Oslo University Hospital - Rikshospitalet, Norway Limited Somatic Hypermutation in IgA of Transglutaminase 2 Specific as well as Gluten Specific Plasma Cells of Celiac Disease Intestinal Lesions
Tuesday, February 12 \| 2:30PM - 4:30PM Workshop 4: Mucosal B Cell Responses Room: Quandary Peak Speaker 6 of 6 Giuliana Magri, Institut Hospital del Mar d'Investigacions Médiques, Spain A Novel Subset of GM-CSF-Producing Innate Lymphoid Cells Links Splenic B Cell-Helper Neutrophils with Marginal Zone B Cells
Tuesday, February 12 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Tuesday, February 12 \| 5:00PM - 7:15PM Mucosal Antibody Responses (Joint) Room: Columbine Ballroom Speaker 1 of 6 * Barton F. Haynes, Duke University Medical Center, USA
Tuesday, February 12 \| 5:00PM - 7:15PM Mucosal Antibody Responses (Joint) Room: Columbine Ballroom Speaker 2 of 6 * Andrea Cerutti, Mount Sinai School of Medicine, USA Mucus and Goblet Cells : New Insights in Intestinal Homeostasis Homeostasis
Tuesday, February 12 \| 5:00PM - 7:15PM Mucosal Antibody Responses (Joint) Room: Columbine Ballroom Speaker 3 of 6 Sidonia Fagarasan, RIKEN Research Center for Allergy and Immunology, Japan IgA Synthesis: A Form of Functional Immune Adaptation Extending Beyond Gut
Tuesday, February 12 \| 5:00PM - 7:15PM Mucosal Antibody Responses (Joint) Room: Columbine Ballroom Speaker 4 of 6 Andrew J.S. Macpherson, University of Bern, Switzerland Mucosal and Systemic Antibody Responses to Commensal Microbes – Induction and Function
Tuesday, February 12 \| 5:00PM - 7:15PM Mucosal Antibody Responses (Joint) Room: Columbine Ballroom Speaker 5 of 6 Duane R. Wesemann, Harvard Medical School, USA Short Talk: Early B Lineage Cell Develompment in the Gut Lamina Propria
Tuesday, February 12 \| 5:00PM - 7:15PM Mucosal Antibody Responses (Joint) Room: Columbine Ballroom Speaker 6 of 6 Olga Malykhina, Northwestern University, USA Short Talk: Cervical and Cervicovaginal Mucus Show Differential Retention of IgA But Similar Retention of IgG -- Implication for HIV Vaccine
Tuesday, February 12 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Colorado Rockies Ballroom
Tuesday, February 12 \| 7:30PM - 10:00PM Poster Session 2 Room: Colorado Rockies Ballroom
Wednesday, February 13 \| 7:00AM - 8:00AM Breakfast Room: Colorado Rockies Ballroom
Wednesday, February 13 \| 8:00AM - 11:15AM Germinal Center, Plasma Cell and Memory B Cell Differentiati on Room: Longs/Grays Peaks Speaker 1 of 6 * Carola G. Vinuesa, Australian National University, Australia Regulation of Tfh Cell-Mediated Selection in Germinal Centers
Wednesday, February 13 \| 8:00AM - 11:15AM Germinal Center, Plasma Cell and Memory B Cell Differentiati on Room: Longs/Grays Peaks Speaker 2 of 6 Jason G. Cyster, HHMI/University of California, San Francisco, USA Lipid Cues and Cell Migration during the Humoral Immune Response
Wednesday, February 13 \| 8:00AM - 11:15AM Germinal Center, Plasma Cell and Memory B Cell Differentiati on Room: Longs/Grays Peaks Speaker 3 of 6 Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA Dendritic Cells and Macrophages Help the Generation of Human Plasma Cells
Wednesday, February 13 \| 8:00AM - 11:15AM Germinal Center, Plasma Cell and Memory B Cell Differentiati on Room: Longs/Grays Peaks Speaker 4 of 6 Tomohiro Kurosaki, Osaka University, Japan B Cell Intrinsic and Extrinsic Mechanisms for Rapid Responsiveness of IgG1 Type Memory B Cells
Wednesday, February 13 \| 8:00AM - 11:15AM Germinal Center, Plasma Cell and Memory B Cell Differentiati on Room: Longs/Grays Peaks Speaker 5 of 6 Christopher C. Goodnow, Garvan Institute of Medical Research, Australia Short Talk: Clonal Anergy, the Function of IgD, and Redemption of Self-Reactive Antibodies in Germinal Centers
Wednesday, February 13 \| 8:00AM - 11:15AM Germinal Center, Plasma Cell and Memory B Cell Differentiati on Room: Longs/Grays Peaks Speaker 6 of 6 Hai Qi, Tsinghua University, China Short Talk: Parenchymal Bystander B Cells Control ICOS-Dependent Follicular Recruitment of Helper T Cells
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 8 * Douglas F. Nixon, Weill Cornell Medicine, USA
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 8 * Stephen A. Migueles, NIAID, National Institutes of Health, USA
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 8 Hendrik Streeck, US Military HIV Research Program, USA HIV-Specific CD4 T-Cells
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 8 Olivier Lambotte, University Paris South, France T-cells in HIV Controllers and the Perspectives for HIV Cure Strategies
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 8 Bruce D. Walker, Ragon Institute of MGH, MIT and Harvard, USA Properties of Protective CD8 T Cell Responses
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 8 Barbara L. Shacklett, University of California, Davis, USA Mucosal T-Cell Responses and HIV Infection
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 8 Brenna J. Hill, Frederick National Laboratories, USA Short Talk: Characterization of SIV-Specific T Cells after Heterologous Mucosal Vaccination
Wednesday, February 13 \| 8:00AM - 11:15AM CD8 and CD4 T Cell Immunity This session is from HIV Vaccines Room: Quandary Peak Speaker 8 of 8 Tomas Hanke, University of Oxford, UK Short Talk: Targeting HIV-1 Where It Hurts: Phase I/ IIa Clinical Trials
Wednesday, February 13 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Wednesday, February 13 \| 10:00AM - 10:00AM On Own for Lunch and Recreation
Wednesday, February 13 \| 11:15AM - 1:00PM Poster Setup Room: Colorado Rockies Ballroom
Wednesday, February 13 \| 1:00PM - 10:00PM Poster Viewing Room: Colorado Rockies Ballroom
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 1 of 9 * Ulf Klein, Columbia University, USA
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 2 of 9 Alexander Dent, Indiana University School of Medicine, USA Dissecting the Role of BCL6 in Normal B Cells
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 3 of 9 Lisa G. Barnett, Genomics Institute of the Novartis Research Foundation, USA Temporally Defined Cognate T Cell-B Cell Interactions Regulate Germinal Center Development
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 4 of 9 Gabriel D. Victora, Rockefeller University, USA c-MYC Is Required for Germinal Center Selection and Cyclic Re-Entry
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 5 of 9 Zahra Sabouri, Australian National University, Australia Antibody Redemption: Removal of Self-Reactivity from IgD+ Anergic B Cells by Purifying Selection in Germinal Centers
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 6 of 9 Kai-Michael Toellner, University of Birmingham, UK Asymmetric B Cell Division Optimises Information Processing in Germinal Centres
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 7 of 9 * Carol E. Schrader, University of Massachusetts, USA AP Endonuclease 2 (APE2) Regulates the Expansion of Germinal Center B Cells by Protecting Against Oxidative Damage
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 8 of 9 Alberto Martin, University of Toronto, Canada Caspase 8 Activity Regulates Germinal Center B Cell Homeostasis and the Generation of High Affinity Antibodies
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 5: Germinal Center B Cell Response Room: Longs/Grays Peaks Speaker 9 of 9 Luise Humpert, Roche, Switzerland Functional Role of CXCR7 Expression on Late Germinal Center B Cells
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 1 of 9 * John C. Cambier, University of Colorado, USA
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 2 of 9 Wei Xu, Roche Innovation Center Zurich, Switzerland Identification of Human Granzyme B-Expressing Plasma Cells
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 3 of 9 Ignacio Sanz, Emory University, School of Medicine, USA Heterogeneity of Antibody Secreting Cell Subsets in Blood after Vaccination and Bone Marrow in Healthy Adults: Identification of Human Long-Lived Plasma Cells
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 4 of 9 Laura Ann George, University of Birmingham, UK Differential Regulation of IRF4 during Extrafollicular B Cell Differentiation, and its Role for Ig Class Switching
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 5 of 9 Mark Wright, Monash University, Australia Plasma Cells Require CD37-Dependent Integrin Signaling for Long-Term Survival
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 6 of 9 * Lynn M. Corcoran, Walter and Eliza Hall Institute of Medical Research, Australia The BTB-ZF Transcription Factor Zbtb20 Is Driven by Irf4 and Promotes Plasma Cell Differentiation
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 7 of 9 Deepta Bhattacharya, Washington University School of Medicine, USA Adjuvant-Specific Regulation of Long-Term Antibody Responses by Zbtb20
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 8 of 9 Daniel Radtke, University of Erlangen, Germany Grb2 Regulates B Cell Maturation, B Cell Memory Responses and Inhibits B Cell Ca2+ Signaling
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 6: Plasma Cell and Memory B Cell Responses Room: Castle Peaks Speaker 9 of 9 Boaz Tirosh, Hebrew University, Israel mTORC1 Activation Promotes Plasma Cell Differentiation and Bypasses the Unfolded Protein Response for Immunoglobulin Secretion
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 1 of 9 * Ann Marshak-Rothstein, University of Massachusetts Medical School, USA
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 2 of 9 * Michael P. Cancro, University of Pennsylvania, USA
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 3 of 9 Joseph D. Dekker, University of Texas at Austin, USA Pathways and Mechanisms by which FOXP1 and BCL11A Contribute to Activated B Cell Diffuse Large B Cell Lymphoma (ABC-DLBCL)
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 4 of 9 Carel J. M. van Noesel, Academic Medical Center, Netherlands Antigen-Driven Lymphoma Growth: A Novel Mutated B-Cell Chronic Lymphocytic Leukemia Subset that Recognizes and Responds to Fungi
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 5 of 9 Saravanan Yuvaraj, Erasmus Medical Centrum, Netherlands The Role of Antigenic Stimulation in the Pathogenesis of Chronic Lymphocytic Leukemia
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 6 of 9 Simone Bürgler, Rikshospitalet and University of Oslo, Norway A Chronic Immune Response between B Cells and T Helper Cells Drives Chronic Lymphocytic Leukemia
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 7 of 9 Nataliya Yeremenko, Academic Medical Center, Netherlands The Role of Bob1 in Rheumatoid Arthritis: Potential Implications for Autoimmunity
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 8 of 9 Simanta Pathak, University of Texas Southwestern Medical Center, USA Overexpression of Fatty Acid Amide Hydrolase Promotes Peripheral B Cell Receptor Revision and Emergence of Polyreactive Antibodies in Lupus Prone Mice
Wednesday, February 13 \| 2:30PM - 4:30PM Workshop 7: Autoimmunity and Neoplasia Room: Quandary Peak Speaker 9 of 9 Nancy L. Monson, University of Texas Southwestern Medical Center, USA B Cells that Display a Particular Somatic Hypermutation Pattern in their Antibody Genes Are Unique to Patients with Multiple Sclerosis and Recognize Neurons and Astrocytes
Wednesday, February 13 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Wednesday, February 13 \| 5:00PM - 7:15PM Protective Antibody Responses Against HIV (Joint) Room: Columbine Ballroom Speaker 1 of 6 * Christiane Moog, INSERM and Université of Strasbourg, France
Wednesday, February 13 \| 5:00PM - 7:15PM Protective Antibody Responses Against HIV (Joint) Room: Columbine Ballroom Speaker 2 of 6 * Diane L. Bolton, US Military HIV Research Program, WRAIR, USA
Wednesday, February 13 \| 5:00PM - 7:15PM Protective Antibody Responses Against HIV (Joint) Room: Columbine Ballroom Speaker 3 of 6 Barton F. Haynes, Duke University Medical Center, USA Antibody Virus Co-evolution in Acutely Infected Patients Followed to Broadly Neutralizing Antibody Induction
Wednesday, February 13 \| 5:00PM - 7:15PM Protective Antibody Responses Against HIV (Joint) Room: Columbine Ballroom Speaker 4 of 6 Peter D. Kwong, NIAID, National Institutes of Health, USA Structural Biology of Sites of HIV-1 Vulnerability to Neutralizing Antibody
Wednesday, February 13 \| 5:00PM - 7:15PM Protective Antibody Responses Against HIV (Joint) Room: Columbine Ballroom Speaker 5 of 6 Dennis R. Burton, The Scripps Research Institute, USA Antibody Protection Against HIV: Broadly Neutralizing MAb PGT121
Wednesday, February 13 \| 5:00PM - 7:15PM Protective Antibody Responses Against HIV (Joint) Room: Columbine Ballroom Speaker 6 of 6 Georgia D. Tomaras, Duke University Medical Center, USA Spectrum of Vaccine-Elicited Humoral Responses
Wednesday, February 13 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Colorado Rockies Ballroom
Wednesday, February 13 \| 7:30PM - 10:00PM Poster Session 3 Room: Colorado Rockies Ballroom
Thursday, February 14 \| 7:00AM - 8:00AM Breakfast Room: Colorado Rockies Ballroom
Thursday, February 14 \| 8:00AM - 11:00AM MicroRNAs and B Cell Neoplasias Room: Longs/Grays Peaks Speaker 1 of 4 * Klaus Rajewsky, Max Delbrück Center for Molecular Medicine, Germany MicroRNAs in Normal and Neoplastic B Cells
Thursday, February 14 \| 8:00AM - 11:00AM MicroRNAs and B Cell Neoplasias Room: Longs/Grays Peaks Speaker 2 of 4 Maryaline Coffre, New York University School of Medicine, USA Short Talk: Role of RNAi in B Cell Development and Maturation
Thursday, February 14 \| 8:00AM - 11:00AM MicroRNAs and B Cell Neoplasias Room: Longs/Grays Peaks Speaker 3 of 4 Louis M. Staudt, NCI, National Institutes of Health, USA Therapeutic Efficacy of B Cell Receptor Signaling Inhibitors in Lymphoma
Thursday, February 14 \| 8:00AM - 11:00AM MicroRNAs and B Cell Neoplasias Room: Longs/Grays Peaks Speaker 4 of 4 David Baltimore, California Institute of Technology, USA MicroRNAs, Inflammation and Cancer
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 7 * Robert A. Seder, NIAID, National Institutes of Health, USA
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 7 * Gregg A. Dean, Colorado State University, USA
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 7 Peter Johannes Holst, BioInnovation Institute, Denmark Short Talk: MHC Class II Associated Invariant Chain as a Genetic Adjuvant in Virus Vectored Vaccines
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 7 Nina Bhardwaj, Icahn School of Medicine at Mount Sinai, USA HIV-DC interactions
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 7 Persephone Borrow, University of Oxford, UK Innate Immune Pressure on Transmitted HIV-1
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 7 Karin Loré, Karolinska Institutet, Sweden Innate mechanisms by which Vaccine Adjuvants Influence HIV Env Immunity in Non-Human Primates
Thursday, February 14 \| 8:00AM - 11:00AM New Concepts in Innate Immunity and Stimulation This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 7 Xu Yu, Massachusetts General Hospital, USA Short Talk: LILRB2 Interaction with HLA Class I Correlates with Outcomes of HIV-1 Infection
Thursday, February 14 \| 9:00AM - 9:20AM Coffee Break Room: Longs Peak Foyer
Thursday, February 14 \| 10:00AM - 10:00AM On Own for Lunch and Recreation
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 8 * Nicole Frahm, Bill & Melinda Gates Medical Research Institute, USA
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 8 * Spyros A. Kalams, Vanderbilt University Medical Center, USA
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 8 Kristin L. Boswell, NIAID, National Institutes of Health, USA Characterization of Peripheral TFH-like Cells in HIV Infection
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 8 Rafael Cubas, Genentech, USA Impaired Peripheral Tfh-mediated B-cell Function Affects Humoral Defenses in Chronic HIV Infected Individuals
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 8 Colin Havenar-Daughton, Vir Biotechnology, USA Ability to Generate HIV-1 Neutralizing Antibodies Is Correlated with Increases in Activated Memory B Cells and Peripheral T Follicular Helper Cells
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 8 Antje Heit, Fred Hutchinson Cancer Research Center, USA HVTN-Tested Candidate HIV Vaccines Induce Early Plasmablast and Tfh-Like Responses in Peripheral Blood
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 8 Kristin Hollister, Indiana University School of Medicine, USA Enhanced Expansion of Follicular T Helper Cells following Vaccination with gp120-Encoding DNA
Thursday, February 14 \| 2:30PM - 4:30PM Workshop 3: CD4+ T Cell Help This session is from HIV Vaccines Room: Quandary Peak Speaker 8 of 8 Patricia Bourguignon, GlaxoSmithKline Vaccines, Belgium Co-Administration of an Adjuvanted HIV-1 Gag-Pol-Nef Fusion Protein (F4/AS01) and Adenovirus-35 Gag-RT-Int-Nef (Ad35-GRIN) Induces Potent, Polyfunctional CD4 and CD8 T-Cell Responses
Thursday, February 14 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Thursday, February 14 \| 5:00PM - 7:00PM Autoimmunity and Regulatory B Cells Room: Longs/Grays Peaks Speaker 1 of 4 * Betty Diamond, Feinstein Institute for Medical Research, USA Negative Regulation of Peripheral Autoreactive B Cells
Thursday, February 14 \| 5:00PM - 7:00PM Autoimmunity and Regulatory B Cells Room: Longs/Grays Peaks Speaker 2 of 4 Robert Brink, Garvan Institute of Medical Research, Australia Censoring Self-Reactive B Cells in the Germinal Center Reaction
Thursday, February 14 \| 5:00PM - 7:00PM Autoimmunity and Regulatory B Cells Room: Longs/Grays Peaks Speaker 3 of 4 Edgar G. Engleman, Stanford University School of Medicine, USA B Cells and Insulin Resistance
Thursday, February 14 \| 5:00PM - 7:00PM Autoimmunity and Regulatory B Cells Room: Longs/Grays Peaks Speaker 4 of 4 Claude-Agnès Reynaud, Necker-Paris Medical School, France Short Talk: B-Cell Depletion in Immune Thrombocytopenia Induces the Settlement of Splenic Long-Lived Plasma Cells
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 1 of 7 * Marie Pancera, Fred Hutchinson Cancer Research Center, USA
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 2 of 7 John R. Mascola, NIAID, National Institutes of Health, USA Genetics of Antibody Elicitation
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 3 of 7 Ruth M. Ruprecht, Texas Biomedical Research Institute, USA Passive Immunization against Mucosal R5 SHIV Transmission with Different Isotypes of Human Neutralizing Monoclonal Antibodies
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 4 of 7 Nicole A. Doria-Rose, NIAID, National Institutes of Health, USA Short Talk: Highly Potent V2-Directed Antibodies with Exceptionally Long CDRH3 that Neutralize HIV-1 Subtype C Viruses
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 5 of 7 Rebecca M. Lynch, George Washington University, USA Short Talk: Effective HIV-1 Neutralization at the CD4-Binding Site through Loop-Based Modes of Antibody Recognition
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 6 of 7 William Schief, International AIDS Vaccine Initiative and The Scripps Research Institute, USA Epitope-Focused HIV Vaccine Design
Thursday, February 14 \| 5:00PM - 7:00PM Antibody Genomics and Immunogen Design This session is from HIV Vaccines Room: Quandary Peak Speaker 7 of 7 * Quentin J. Sattentau, Sir William Dunn School of Pathology, UK Chemical Modification of Env for HIV-1 Vaccine Design
Thursday, February 14 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Colorado Rockies Ballroom
Thursday, February 14 \| 8:00PM - 11:00PM Entertainment Room: Colorado Rockies Ballroom
Thursday, February 14 \| 8:00PM - 11:00PM Cash Bar Room: Colorado Rockies Ballroom
Friday, February 15 \| 10:23AM - 10:23AM Departure *Session Chair †Invited, not yet responded.