Web Desc
Mechanisms and Consequences of Invertebrate-Microbe Interactions
Organizer(s): Bruno Lemaitre, Nicole M. Gerardo and Jason Rasgon
Date: January 26 - 30, 2014
Location: Granlibakken Tahoe, Tahoe City, CA, USA
Supported by the Directors' Fund
Summary of Meeting:
Our understanding of invertebrate-microbe interactions has broadened dramatically in the past quarter century. At the mechanistic level, we have discovered immune mechanisms conserved across organisms. At the ecological level, we have gained appreciation for the complex spectrum of cooperative and detrimental interactions that hosts have with microbes. A comprehensive understanding of host-microbe interactions is integral to limiting the ability of organisms, particularly insects, to spread diseases that impact human health and destroy crops. Study of invertebrate-microbe interactions also provides insight into the role that beneficial microbes play in the health of all organisms. Despite advances, there is a need to integrate mechanistic, genomic, ecological and applied approaches. To date, few meetings have brought together researchers from across disciplines who are working on invertebrate-microbe symbioses. This symposium will host scientists studying diverse aspects of invertebrate-microbe interactions in different systems (e.g., squid, leeches, flies, nematodes, bees). Attendees will include molecular biologists studying immune mechanisms and evolutionary ecologists working on pest control in the field. Talks will focus on both beneficial and harmful microbial associations, allowing cross-fertilization of knowledge from one system to another and providing impetus for further fundamental advances and applied applications. The meeting goals include: 1) Incorporating speakers who work on diverse systems; 2) Engaging participants who are addressing these interactions from both the microbial and host perspectives; 3) Highlighting research that ranges in focus from molecular mechanisms to ecological-evolutionary aspects; 4) Increasing dialogue between researchers working on both beneficial and harmful microbial associations.
Scholarship Deadline: October 9 2013
Discounted Abstract Deadline: October 9 2013
Abstract Deadline: November 4 2013
Discounted Registration Deadline: November 25 2013
We gratefully acknowledge additional support for this conference from:
New England Biolabs, Inc.
$1 - $2,499

Entomological Society of America
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Entomological Society of America
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 26 | 4:00PM - 8:00PM
Arrival and Registration
Room: Pre Function


Sunday, January 26 | 6:00PM - 8:00PM
Refreshments
Room: Granhall


Monday, January 27 | 7:00AM - 8:00AM
Breakfast
Room: Granhall


Monday, January 27 | 8:00AM - 9:10AM
Keynote Address
Room: Mountain/Lake

Speaker 1 of 2
* Bruno Lemaitre, École Polytechnique Fédérale de Lausanne, Switzerland
Conference Introduction

Monday, January 27 | 8:00AM - 9:10AM
Keynote Address
Room: Mountain/Lake

Speaker 2 of 2
Nicole Dubilier, Max Planck Institute for Marine Microbiology, Germany
The Taming of Toxins: Symbionts of Deep-Sea Hydrothermal Vent Mussels Use an Arsenal of Highly Abundant and Diverse Toxins for Host Colonization and Persistence

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 1 of 7
* Jonathan Ewbank, Centre d'Immunologie de Marseille-Luminy, France

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 2 of 7
* Marcelo Jacobs-Lorena, Johns Hopkins Bloomberg School of Public Health, USA

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 3 of 7
Bruno Lemaitre, École Polytechnique Fédérale de Lausanne, Switzerland
Peptidoglycan Recognitions Proteins in Drosophila: An Overview with New Data

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 4 of 7
Emily Troemel, University of California, San Diego, USA
Perturbation of Core Processes Triggers Host Defense against Pathogen Infection in C. elegans

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 5 of 7
Juris A. Grasis, San Diego State University, USA
Coevolution of an Ancient Immune System with a Microbiota: Insights from the Hydra Holobiont

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 6 of 7
Will Wood, University of Edinburgh, UK
Short Talk: Detecting Damage and Developing Immunity in the Drosophila Embryo

Monday, January 27 | 9:10AM - 11:45AM
Advances in Understanding of Invertebrate Immunity
Room: Mountain/Lake

Speaker 7 of 7
Maria-Carla Saleh, Institut Pasteur, France
Short Talk: Evidence of Long-Lasting Antiviral Immunity in Insects

Monday, January 27 | 9:40AM - 10:00AM
Coffee Break
Room: Pre Function


Monday, January 27 | 11:45AM - 1:00PM
Poster Setup
Room: Bay


Monday, January 27 | 11:45AM - 2:30PM
On Own for Lunch and Recreation


Monday, January 27 | 1:00PM - 10:00PM
Poster Viewing
Room: Bay


Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 1 of 10
* Takema Fukatsu, National Institute of Advanced Industrial Science and Technology, Japan

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 2 of 10
* Heidi Goodrich-Blair, University of Wisconsin-Madison, USA

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 3 of 10
Cleo Pietschke, Zoological Institute of the CAU Kiel, Germany
Hydra Polyps Inactivate Quorum Sensing Molecules of Colonizing Bacteria by a Novel Mechanism

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 4 of 10
Katherine M. Buckley, University of Toronto, Canada
Characterization of a Gut-Associated Innate Immune Response in a Simple Invertebrate Using a Gene Regulatory Network Approach

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 5 of 10
Robert M. Brucker, Vanderbilt University, USA
Phylosymbiosis and the Hologenome Concept of Evolution

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 6 of 10
Hirotaka Kanuka, Jikei University School of Medicine, Japan
Odor-Based Mechanical Transmission of Bacteria by Fly Feces

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 7 of 10
Jiyeun Kate Kim, Pusan National University, South Korea
Two Faces of the Lipopolysaccharide O-Antigen of Burkholderia Gut Symbiont in Association with Host Stink Bug

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 8 of 10
Jeremy Herren, International Centre of Insect Physiology and Ecology, icipe, Kenya
The Mechanistic Basis of Interactions between Endosymbiotic Spiroplasma and Host Drosophila

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 9 of 10
Wolfgang J. Miller, Medical University of Vienna, Austria
The Impact of Endosymbiotic Wolbachia on Drosophila Olfaction, Sexual Behavior and Speciation

Monday, January 27 | 2:30PM - 4:30PM
Workshop
Room: Mountain/Lake

Speaker 10 of 10
James Angus Chandler, California Academy of Sciences, USA
Characterization of the Aedes aegypti Microbiota Using RNA Metagenomics

Monday, January 27 | 4:30PM - 5:00PM
Coffee Available
Room: Pre Function


Monday, January 27 | 5:00PM - 7:00PM
Pathogens and Biocontrol
Room: Mountain/Lake

Speaker 1 of 5
* Emily Troemel, University of California, San Diego, USA

Monday, January 27 | 5:00PM - 7:00PM
Pathogens and Biocontrol
Room: Mountain/Lake

Speaker 2 of 5
Raymond J. St. Leger, University of Maryland, USA
Using Entomopathogenic Fungi to Control Arthropod-Borne Pathogens

Monday, January 27 | 5:00PM - 7:00PM
Pathogens and Biocontrol
Room: Mountain/Lake

Speaker 3 of 5
Heidi Goodrich-Blair, University of Wisconsin-Madison, USA
Causes and Consequences of Intestinal Colonization Explored in a Nematode-Bacterium Symbiosis

Monday, January 27 | 5:00PM - 7:00PM
Pathogens and Biocontrol
Room: Mountain/Lake

Speaker 4 of 5
Jonathan Ewbank, Centre d'Immunologie de Marseille-Luminy, France
Host-Fungus Interactions Modeled in C. elegans

Monday, January 27 | 5:00PM - 7:00PM
Pathogens and Biocontrol
Room: Mountain/Lake

Speaker 5 of 5
Joshua Meisel, Massachusetts Institute of Technology, USA
Short Talk: Microbe-Induced Changes of Neuronal TGF-beta Signaling Promote Pathogen Avoidance Behavior in C. elegans

Monday, January 27 | 7:00PM - 8:00PM
Dinner
Room: Granhall


Monday, January 27 | 7:30PM - 10:00PM
Poster Session 1
Room: Bay


Monday, January 27 | 8:00PM - 9:00PM
Social Hour
Room: Bay


Tuesday, January 28 | 7:00AM - 8:00AM
Breakfast
Room: Granhall


Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 1 of 7
* Margaret J. McFall-Ngai, University of Hawai‘i at Manoa, USA

Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 2 of 7
Nancy A. Moran, University of Texas at Austin, USA
Gut Microbial Communities in Honey Bees and Bumble Bees

Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 3 of 7
Won-Jae Lee, Seoul National University, South Korea
Bacterial Uracil and DUOX Activation in Gut-Microbe Symbiosis and Dysbiosis in Drosophila

Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 4 of 7
Takema Fukatsu, National Institute of Advanced Industrial Science and Technology, Japan
Evolutionary Origins of Mutualistic Bacterial Symbionts in Natural Insect Populations: From Free-Living through Facultative to Obligate Associations

Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 5 of 7
Nicole M. Gerardo, Emory University, USA
The Complex Interplay of Protective Facultative Symbionts and Host Immunity

Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 6 of 7
Hassan S. Salem, Max Planck Institute for Chemical Ecology, Germany
Short Talk: The Elemental Value of Gut Symbionts to the Vitamin Metabolism of Firebugs

Tuesday, January 28 | 8:00AM - 11:15AM
Understanding the Function of Complex Host-Associated Microb
ial Communities

Room: Mountain/Lake

Speaker 7 of 7
Julie C. Reveillaud, Marine Biological Laboratory, USA
Short Talk: Host-Specificity Among Abundant and Rare Taxa in the Sponge Microbiome

Tuesday, January 28 | 9:20AM - 9:40AM
Coffee Break
Room: Pre Function


Tuesday, January 28 | 11:15AM - 1:00PM
Poster Setup
Room: Bay


Tuesday, January 28 | 11:15AM - 5:00PM
On Own for Lunch and Recreation


Tuesday, January 28 | 1:00PM - 10:00PM
Poster Viewing
Room: Bay


Tuesday, January 28 | 4:30PM - 5:00PM
Coffee Available
Room: Pre Function


Tuesday, January 28 | 5:00PM - 7:00PM
Establishment of Host-Microbe Associations
Room: Mountain/Lake

Speaker 1 of 6
* Nicole M. Gerardo, Emory University, USA

Tuesday, January 28 | 5:00PM - 7:00PM
Establishment of Host-Microbe Associations
Room: Mountain/Lake

Speaker 2 of 6
* Nancy A. Moran, University of Texas at Austin, USA

Tuesday, January 28 | 5:00PM - 7:00PM
Establishment of Host-Microbe Associations
Room: Mountain/Lake

Speaker 3 of 6
Margaret J. McFall-Ngai, University of Hawai‘i at Manoa, USA
First Words: The Initial Molecular Dialogue between Host and Symbiont during Establishment of a Partnership

Tuesday, January 28 | 5:00PM - 7:00PM
Establishment of Host-Microbe Associations
Room: Mountain/Lake

Speaker 4 of 6
Joerg Graf, University of Connecticut, USA
Temporal Dynamics of Microbe-Host Interactions in the Digestive Tract of the Medicinal Leech

Tuesday, January 28 | 5:00PM - 7:00PM
Establishment of Host-Microbe Associations
Room: Mountain/Lake

Speaker 5 of 6
Marcelo Jacobs-Lorena, Johns Hopkins Bloomberg School of Public Health, USA
Fighting Malaria with Engineered Symbiotic Bacteria from Vector Mosquitoes

Tuesday, January 28 | 5:00PM - 7:00PM
Establishment of Host-Microbe Associations
Room: Mountain/Lake

Speaker 6 of 6
Larry J. Dishaw, University of South Florida, USA
Short Talk: Ciona intestinalis and the Evolution of Chordate Gut-Microbial Interactions

Tuesday, January 28 | 7:00PM - 8:00PM
Dinner
Room: Granhall


Tuesday, January 28 | 7:30PM - 10:00PM
Poster Session 2
Room: Bay


Tuesday, January 28 | 8:00PM - 9:00PM
Social Hour
Room: Bay


Wednesday, January 29 | 7:00AM - 8:00AM
Breakfast
Room: Granhall


Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 1 of 8
* Jason L. Rasgon, Pennsylvania State University, USA

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 2 of 8
* Serap Aksoy, Yale University School of Public Health, USA

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 3 of 8
Frank Jiggins, UK
Why Do Insects Vary in Susceptibility to Infection?

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 4 of 8
Todd A. Schlenke, Reed College, USA
Drosophila-Wasp Coevolution: From Ecology to Mechanism

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 5 of 8
Brian P. Lazzaro, Cornell University, USA
Complexity in the Function and Evolution of Insect Immunity

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 6 of 8
David S. Schneider, Stanford University School of Medicine, USA
Warping Disease Space to Improve Recovery from Infections

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 7 of 8
Rebecca P. Duncan, University of Miami, USA
Short Talk: Dynamic Recruitment of Amino Acid Transporters to the Insect-Symbiont Interface

Wednesday, January 29 | 8:00AM - 11:15AM
Ecology and Evolution of Host Immune Defense
Room: Mountain/Lake

Speaker 8 of 8
Marilou P. Sison-Mangus, University of California, Santa Cruz, USA
Short Talk: The Acquisition of Microbiota and their Consequences in the Life History Traits of the Crustacean Model, Daphnia

Wednesday, January 29 | 9:20AM - 9:40AM
Coffee Break
Room: Pre Function


Wednesday, January 29 | 11:15AM - 5:00PM
On Own for Lunch and Recreation


Wednesday, January 29 | 4:30PM - 5:00PM
Coffee Available
Room: Pre Function


Wednesday, January 29 | 5:00PM - 7:00PM
Hosts, Symbionts and Insect Vectors
Room: Mountain/Lake

Speaker 1 of 6
* David S. Schneider, Stanford University School of Medicine, USA

Wednesday, January 29 | 5:00PM - 7:00PM
Hosts, Symbionts and Insect Vectors
Room: Mountain/Lake

Speaker 2 of 6
* Nicole Dubilier, Max Planck Institute for Marine Microbiology, Germany

Wednesday, January 29 | 5:00PM - 7:00PM
Hosts, Symbionts and Insect Vectors
Room: Mountain/Lake

Speaker 3 of 6
Serap Aksoy, Yale University School of Public Health, USA
Tsetse Flies, Trypanosomes and Endosymbionts

Wednesday, January 29 | 5:00PM - 7:00PM
Hosts, Symbionts and Insect Vectors
Room: Mountain/Lake

Speaker 4 of 6
George Dimopoulos, Johns Hopkins University, USA
Blocking Human Pathogens with the Mosquito Microbiome

Wednesday, January 29 | 5:00PM - 7:00PM
Hosts, Symbionts and Insect Vectors
Room: Mountain/Lake

Speaker 5 of 6
Jason L. Rasgon, Pennsylvania State University, USA
Symbiont-Mediated Control of Insect Vectors: Mechanisms of Wolbachia-Induced Pathogen Suppression in Anopheles Mosquitoes

Wednesday, January 29 | 5:00PM - 7:00PM
Hosts, Symbionts and Insect Vectors
Room: Mountain/Lake

Speaker 6 of 6
Guillaume Carissimo, Institut Pasteur, France
Short Talk: Midgut Immunity of Anopheles gambiae to Arbovirus Infection

Wednesday, January 29 | 7:00PM - 7:15PM
Closing Remarks
Room: Mountain/Lake

Speaker 1 of 1
Jason L. Rasgon, Pennsylvania State University, USA

Wednesday, January 29 | 7:15PM - 8:15PM
Dinner
Room: Granhall


Wednesday, January 29 | 7:15PM - 8:15PM
Social Hour
Room: Granhall


Wednesday, January 29 | 8:00PM - 11:00PM
Entertainment
Room: Granhall


Wednesday, January 29 | 8:00PM - 11:00PM
Cash Bar
Room: Granhall


Thursday, January 30 | 10:25AM - 10:25AM
Departure


*Session Chair.