Web Desc
Big Data in Biology
Organizer(s): Lincoln D. Stein, Doreen Ware and Michael Schatz
Date: March 23 - 25, 2014
Location: Fairmont San Francisco, San Francisco, California, USA
Sponsored by H3 Biomedicine Inc. and Nestlé Institute of Health Sciences
For important information on the coronavirus, please click here
Summary of Meeting:
Biology has arrived at an interesting juncture. The last decade has seen an unprecedented explosion in the amount of information generated by the biological research community, and a concomitant rise in the challenges of sharing, archiving, integrating and analyzing it. This is particularly acute in genomics, where next generation sequencing technologies are accelerating faster than Moore's Law. Serendipitously, this explosion of biological data has come at the same time that computer scientists have developed scalable data management solutions for handling the vastness of the internet; solutions including distributed file systems, cloud computing, and algorithms for efficient data-intensive computation across multiple machines. This conference will bring together biologists and computer scientists from industry and academia to discuss the challenges and trends in this quickly evolving field. The goals include: * Surveying data and computation challenges in the fields of genomics, medical genetics, neuroinformatics, biological imaging and agronomics. * Identifying critical bottlenecks in distributing biological data to the community. * Discussing solutions to growing problem of data sets that are 'too big to download.' * Debating the tension between community access to personal genomic data sets (e.g. cancer genomes) and potential impact on patient privacy. What makes this conference unique is that it examines a common problem, 'How do we handle big data?' across multiple research specialties that rarely interact. We are bringing together plant scientists, medical geneticists, genomicists, microscopists and neurobiologists. The expected outcome is a greater understanding of the challenges each field faces, and the solutions that they have found.
Scholarship Deadline: November 19 2013
Discounted Abstract Deadline: November 19 2013
Abstract Deadline: December 18 2013
Discounted Registration Deadline: January 21 2014
Abstacts when book is in proofing process


Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
H3 Biomedicine Inc.Nestlé Institute of Health Sciences
$2,500 - $9,999
Big Data journal from Mary Ann Liebert, Inc. Publishers
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
Big Data Journal from Mary Ann Liebert, Inc. Publishers
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 23 | 6:00PM - 8:00PM
Registration and Refreshments
Room: Cirque


Monday, March 24 | 7:00AM - 8:30AM
Arrival and Registration
Room: Garden Room


Monday, March 24 | 8:00AM - 8:30AM
Breakfast
Room: Gold Room


Monday, March 24 | 8:30AM - 9:30AM
Keynote Address: Cancer Hub
Room: Venetian Room

Speaker 1 of 2
* Lincoln D. Stein, Ontario Institute for Cancer Research, Canada
Opening Remarks

Monday, March 24 | 8:30AM - 9:30AM
Keynote Address: Cancer Hub
Room: Venetian Room

Speaker 2 of 2
David Haussler, University of California, Santa Cruz, USA
Large-Scale Cancer Genomics

Monday, March 24 | 9:30AM - 12:00PM
Databases and Clouds I
Room: Venetian Room

Speaker 1 of 4
Laura Clarke, European Bioinformatics Institute, UK
The 1000 Genomes Project, Community Access and Management for Large Scale Public Data

Monday, March 24 | 9:30AM - 12:00PM
Databases and Clouds I
Room: Venetian Room

Speaker 2 of 4
Dan Stanzione, University of Texas at Austin, USA
The iPlant Collaborative: Cyberinfrastructure for 21st Century Biology

Monday, March 24 | 9:30AM - 12:00PM
Databases and Clouds I
Room: Venetian Room

Speaker 3 of 4
Jill P. Mesirov, Broad Institute, USA
GenomeSpace: A Community Web Environment for Genomic Analysis Across Diverse Bioinformatic Tools

Monday, March 24 | 9:30AM - 12:00PM
Databases and Clouds I
Room: Venetian Room

Speaker 4 of 4
Francis Ouellette, Génome Québec, Canada
Short Talk: FGED: The Functional Genomics Data Society

Monday, March 24 | 10:10AM - 10:30AM
Coffee Break
Room: Gold Room


Monday, March 24 | 12:00PM - 1:00PM
Poster Setup
Room: Gold Room


Monday, March 24 | 12:00PM - 1:00PM
Lunch
Room: Gold Room


Monday, March 24 | 1:00PM - 2:15PM
Databases and Clouds II
Room: Venetian Room

Speaker 1 of 3
* Michael Schatz, Cold Spring Harbor Laboratory, USA

Monday, March 24 | 1:00PM - 2:15PM
Databases and Clouds II
Room: Venetian Room

Speaker 2 of 3
Andrew Carroll, DNAnexus, USA
Insights from the Genomic Analysis of 10,940 Exomes and 3,751 Whole Genomes Demystifying Running at Scale and the Scientific

Monday, March 24 | 1:00PM - 2:15PM
Databases and Clouds II
Room: Venetian Room

Speaker 3 of 3
John Overington, Medicines Discovery Catapult, UK
Spanning Molecular and Genomic Data in Drug Discovery

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 1 of 8
* Doreen Ware, Cold Spring Harbor Laboratory, USA

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 2 of 8
Michael Schatz, Cold Spring Harbor Laboratory, USA

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 3 of 8
David Haussler, University of California, Santa Cruz, USA

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 4 of 8
Laura Clarke, European Bioinformatics Institute, UK

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 5 of 8
Jill P. Mesirov, Broad Institute, USA

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 6 of 8
Andrew Carroll, DNAnexus, USA

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 7 of 8
Lincoln D. Stein, Ontario Institute for Cancer Research, Canada

Monday, March 24 | 2:15PM - 4:00PM
Panel: Big Data Challenges and Solutions: Control Access to
Individual Genomes
Room: Venetian Room

Speaker 8 of 8
Mark Gerstein, Yale University, USA

Monday, March 24 | 2:15PM - 7:00PM
Poster Viewing
Room: Gold Room


Monday, March 24 | 4:00PM - 5:00PM
Social Hour
Room: Gold Room


Monday, March 24 | 5:00PM - 7:00PM
Poster Session
Room: Gold Room


Tuesday, March 25 | 8:00AM - 8:30AM
Breakfast
Room: Gold Room


Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 1 of 8
* Doreen Ware, Cold Spring Harbor Laboratory, USA

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 2 of 8
Lincoln D. Stein, Ontario Institute for Cancer Research, Canada
The International Cancer Genome Consortium Database

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 3 of 8
Ajay Royyuru, IBM T.J. Watson Research Center, USA
Genome Analysis with IBM Watson

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 4 of 8
Mark Gerstein, Yale University, USA
Human Genome Analysis

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 5 of 8
Stuart Young, Annai Systems Inc., USA
The BioCompute Farm: Colocated Compute for Cancer Genomics

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 6 of 8
Robert L. Grossman, University of Chicago, USA
Short Talk: An Overview of the Bionimbus Protected Data Cloud

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 7 of 8
Adam Butler, Wellcome Trust Sanger Institute, UK
Short Talk: Pan-Cancer Analysis of Somatic Variation from Whole Genome ICGC / TCGA Datasets

Tuesday, March 25 | 8:30AM - 12:00PM
Personal Genomes
Room: Venetian Room

Speaker 8 of 8
Maya M. Kasowski, Howard Hughes Medical Institute, USA
Short Talk: Extensive Variation in Chromatin States Across Humans

Tuesday, March 25 | 9:50AM - 10:10AM
Coffee Break
Room: Gold Room


Tuesday, March 25 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.

Tuesday, March 25 | 12:00PM - 1:00PM
Lunch
Room: Gold Room


Tuesday, March 25 | 1:00PM - 3:00PM
Imaging/Pharmacogenomics
Room: Venetian Room

Speaker 1 of 4
Susan Sunkin, Allen Institute for Brain Science, USA
Allen Brain Atlas: An Integrated Neuroscience Resource

Tuesday, March 25 | 1:00PM - 3:00PM
Imaging/Pharmacogenomics
Room: Venetian Room

Speaker 2 of 4
Jason R. Swedlow, University of Dundee, Scotland
The Open Microscopy Environment: Open Source Image Informatics for the Biological Sciences

Tuesday, March 25 | 1:00PM - 3:00PM
Imaging/Pharmacogenomics
Room: Venetian Room

Speaker 3 of 4
Douglas P.W. Russell, University of Oxford, UK
Short Talk: Decentralizing Image Informatics

Tuesday, March 25 | 1:00PM - 3:00PM
Imaging/Pharmacogenomics
Room: Venetian Room

Speaker 4 of 4
* Michael Schatz, Cold Spring Harbor Laboratory, USA
Scalable Solutions for Next-Gen Sequence Analysis

Tuesday, March 25 | 3:00PM - 3:15PM
Closing Remarks

Speaker 1 of 1
Michael Schatz, Cold Spring Harbor Laboratory, USA