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Web Desc
Inflammatory Diseases: Recent Advances in Basic and Translational Research and Therapeutic Treatments joint with Emerging Cytokine Networks Organizer(s): Chen Dong, Tadamitsu Kishimoto and Richard A. Flavell Date: January 17 - 22, 2014 Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada Sponsored by Biogen Idec, Boehringer Ingelheim Pharmaceuticals, Inc., Janssen R&D: Pharmaceutical Companies of Johnson & Johnson, Novo Nordisk A/S and Pfizer Inc. Summary of Meeting: Chronic inflammatory diseases represent a major threat to the health of our society. In the past several years, there have been advancements in understanding the immunological basis for inflammatory diseases and in identifying the cellular components and molecular pathways underlying their pathogenesis. Systems approaches have been taken in translational research of human patients. In addition, new biological and small molecule drugs have been tested with different degrees of success. The goal of this meeting is review these advances and to provide a single forum for basic, clinical and industrial experts to consider opportunities for further development of concepts, systems and therapeutics. This will be achieved by: 1) covering multiple types of inflammatory diseases that affect multiple organs; 2) gathering basic scientists, translational researchers and pharmaceutical investigators in the same setting; and 3) featuring roundtable discussion on future improvements in animal models and approaches to study human diseases and drug responses. We anticipate that this meeting will foster discussion on common pathways in inflammatory diseases, common methodology in studying human diseases and common challenges in designing the best medicine and clinical trials. Scholarship Deadline: October 8 2013 Discounted Abstract Deadline: October 8 2013 Abstract Deadline: October 30 2013 Discounted Registration Deadline: November 18 2013 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: GlaxoSmithKline Novartis Institutes for BioMedical Research Novartis Pharma AG We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Inflammatory Diseases: Recent Advances in Basic and Translational Research and Therapeutic Treatments

joint with Emerging Cytokine Networks

Organizer(s): Chen Dong, Tadamitsu Kishimoto and Richard A. Flavell

Date: January 17 - 22, 2014
Location: Fairmont Hotel Vancouver, Vancouver, BC, Canada

Sponsored by Biogen Idec, Boehringer Ingelheim Pharmaceuticals, Inc., Janssen R&D: Pharmaceutical Companies of Johnson & Johnson, Novo Nordisk A/S and Pfizer Inc.

Summary of Meeting:

Chronic inflammatory diseases represent a major threat to the health of our society. In the past several years, there have been advancements in understanding the immunological basis for inflammatory diseases and in identifying the cellular components and molecular pathways underlying their pathogenesis. Systems approaches have been taken in translational research of human patients. In addition, new biological and small molecule drugs have been tested with different degrees of success. The goal of this meeting is review these advances and to provide a single forum for basic, clinical and industrial experts to consider opportunities for further development of concepts, systems and therapeutics. This will be achieved by: 1) covering multiple types of inflammatory diseases that affect multiple organs; 2) gathering basic scientists, translational researchers and pharmaceutical investigators in the same setting; and 3) featuring roundtable discussion on future improvements in animal models and approaches to study human diseases and drug responses. We anticipate that this meeting will foster discussion on common pathways in inflammatory diseases, common methodology in studying human diseases and common challenges in designing the best medicine and clinical trials.

Scholarship Deadline: October 8 2013

Discounted Abstract Deadline: October 8 2013

Abstract Deadline: October 30 2013

Discounted Registration Deadline: November 18 2013

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

Boehringer Ingelheim Pharmaceuticals, Inc.

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

GlaxoSmithKline

Novartis Institutes for BioMedical Research

Novartis Pharma AG

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Friday, January 17 \| 4:00PM - 8:00PM Arrival and Registration Room: British/Columbia Foyer
Saturday, January 18 \| 7:30AM - 8:30AM Breakfast Room: Pacific Ballroom
Saturday, January 18 \| 8:30AM - 10:30AM Keynote Session (Joint) Room: British/Columbia Ballroom Speaker 1 of 4 * Daniel J. Cua, Janssen Pharmaceutical Companies of Johnson & Johnson, USA
Saturday, January 18 \| 8:30AM - 10:30AM Keynote Session (Joint) Room: British/Columbia Ballroom Speaker 2 of 4 * Chen Dong, Tsinghua University, China
Saturday, January 18 \| 8:30AM - 10:30AM Keynote Session (Joint) Room: British/Columbia Ballroom Speaker 3 of 4 Ruslan Medzhitov, HHMI/Yale University School of Medicine, USA Inflammation
Saturday, January 18 \| 8:30AM - 10:30AM Keynote Session (Joint) Room: British/Columbia Ballroom Speaker 4 of 4 Fiona M. Powrie, University of Oxford, UK Cytokine Network Regulating Adaptive and Innate Immunity
Saturday, January 18 \| 10:30AM - 10:50AM Coffee Break Room: British/Columbia Foyer
Saturday, January 18 \| 10:50AM - 12:15PM Cytokine Regulation of Inflammation (Joint) Room: British/Columbia Ballroom Speaker 1 of 4 * Tadamitsu Kishimoto, Osaka University, Japan
Saturday, January 18 \| 10:50AM - 12:15PM Cytokine Regulation of Inflammation (Joint) Room: British/Columbia Ballroom Speaker 2 of 4 Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA The NLR Gene Family and Cytokines
Saturday, January 18 \| 10:50AM - 12:15PM Cytokine Regulation of Inflammation (Joint) Room: British/Columbia Ballroom Speaker 3 of 4 David Artis, Weill Cornell Medical College, USA Regulation of Barrier Immunity
Saturday, January 18 \| 10:50AM - 12:15PM Cytokine Regulation of Inflammation (Joint) Room: British/Columbia Ballroom Speaker 4 of 4 Christoph Wilhelm, University of Bonn, Germany Short Talk: Adaptation of Innate Lymphoid Cells to Nutrient Deprivation Promotes Type 2 Barrier Immunity
Saturday, January 18 \| 12:15PM - 1:00PM Poster Setup Room: Pacific Ballroom
Saturday, January 18 \| 12:15PM - 5:00PM On Own for Lunch and Recreation
Saturday, January 18 \| 1:00PM - 10:00PM Poster Viewing Room: Pacific Ballroom
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 9 * Rene de Waal Malefyt, Merck Research Labs, USA
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 9 Yosuke Kumamoto, Rutgers New Jersey Medical School, USA CD301b+ Dermal DCs Are Required for Th2 Cell Immunity
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 9 Marina Babic Cac, German Rheumatism Research Centre, Germany The Activating Receptor NKG2D Regulates IL-10 Expression in Th1 Cells
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 9 Mei Li, Institut de Génétique et de Biologie Moleculaire et Cellulaire, France Skin Thymic Stromal Lymphopoietin Initiates Th2 Responses through an Orchestrated Immune Cascade
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 9 Julien J. Karrich, Erasmus University Medical Center, Netherlands Characterization of Plet1-Expressing DCs in the Intestine and Their Role in Controlling IL22-Driven Mucosal Innate Immunity
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 6 of 9 Jochem H.J. Bernink, Tytgat Institute, Netherlands Mononuclear Phagocytes Regulate the Balance between Group 1 and Group 3 Innate Lymphoid Cells in Mucosal Tissues
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 7 of 9 Christina Chang, The Salk Institute, USA REV-ERBs as Negative Regulators of the Th17 Immune Response
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 8 of 9 Sergei P. Atamas, University of Maryland School of Medicine, USA Functionally Distinct Cytokine Patterns Evoked by Precursor and Mature IL-33
Saturday, January 18 \| 2:30PM - 4:30PM Workshop 1 This session is from Emerging Cytokines Room: British Ballroom Speaker 9 of 9 Brian T. Edelson, Washington University School of Medicine, USA Bhlhe40 Regulates T Cell Cytokine Production and Is Essential for Autoimmune Neuroinflammation
Saturday, January 18 \| 4:30PM - 5:00PM Coffee Available Room: British/Columbia Foyer
Saturday, January 18 \| 5:00PM - 7:15PM New Targets and Treatment in Allergic Diseases Room: Columbia Ballroom Speaker 1 of 6 * Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA
Saturday, January 18 \| 5:00PM - 7:15PM New Targets and Treatment in Allergic Diseases Room: Columbia Ballroom Speaker 2 of 6 Yong-Jun Liu, Sanofi, USA Regulators of Th2 Immunity
Saturday, January 18 \| 5:00PM - 7:15PM New Targets and Treatment in Allergic Diseases Room: Columbia Ballroom Speaker 3 of 6 Rene de Waal Malefyt, Merck Research Labs, USA Talk Title to be Announced
Saturday, January 18 \| 5:00PM - 7:15PM New Targets and Treatment in Allergic Diseases Room: Columbia Ballroom Speaker 4 of 6 John G. Matthews, Genentech, Inc., USA Lebrikizumab (Anti-IL-13) Treatment for Asthma
Saturday, January 18 \| 5:00PM - 7:15PM New Targets and Treatment in Allergic Diseases Room: Columbia Ballroom Speaker 5 of 6 Hongbo Chi, St. Jude Children's Research Hospital, USA Short Talk: mTORC1-Dependent Metabolic Programming of Exit from Quiescence Underlies T Cell Fate Decisions and Inflammation
Saturday, January 18 \| 5:00PM - 7:15PM New Targets and Treatment in Allergic Diseases Room: Columbia Ballroom Speaker 6 of 6 Emily Hams, Trinity College Dublin, Ireland Short Talk: Type 2 Innate Lymphoid Cells Regulate Obesity in Mice
Saturday, January 18 \| 5:00PM - 7:00PM Regulation of Tissue-Resident ILC and T Cells This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 5 * Richard M. Locksley, HHMI/University of California, San Francisco, USA
Saturday, January 18 \| 5:00PM - 7:00PM Regulation of Tissue-Resident ILC and T Cells This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 5 Hergen Spits, University of Amsterdam, Netherlands Regulation of Development and Function of Human ILC
Saturday, January 18 \| 5:00PM - 7:00PM Regulation of Tissue-Resident ILC and T Cells This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 5 Yasmine Belkaid, NIAID, National Institutes of Health, USA Compartmentalized and Systemic Control of Tissue Immunity by Commensals
Saturday, January 18 \| 5:00PM - 7:00PM Regulation of Tissue-Resident ILC and T Cells This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 5 Hilde Cheroutre, La Jolla Institute for Allergy and Immunology, USA New Emerging Transcription Factor- and Cytokine Networks at the Mucosal Interface of the Intestine
Saturday, January 18 \| 5:00PM - 7:00PM Regulation of Tissue-Resident ILC and T Cells This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 5 Michael G. Constantinides, The Scripps Research Institute, USA Short Talk: A Committed Precursor to Innate Lymphoid Cells
Saturday, January 18 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Pacific Ballroom
Saturday, January 18 \| 7:30PM - 10:00PM Poster Session 1 Room: Pacific Ballroom
Sunday, January 19 \| 7:30AM - 8:30AM Breakfast Room: Pacific Ballroom
Sunday, January 19 \| 8:00AM - 8:30AM Poster Setup Room: Pacific Ballroom
Sunday, January 19 \| 8:30AM - 7:00PM Poster Viewing Room: Pacific Ballroom
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 1 of 8 * Yong-Jun Liu, Sanofi, USA
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 2 of 8 Shimon Sakaguchi, Osaka University, Japan Roles of Treg Cells in Inflammation
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 3 of 8 Chen Dong, Tsinghua University, China Regulation and Modulation of Th17 and Tfh Cells in Inflammation
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 4 of 8 K. Frank Austen, Harvard Medical School, USA Integration of Three Cysteinyl Leukotriene Receptors and their Preferred Ligands into Models of Dectin-2-Dependent ‘Asthma’
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 5 of 8 Wanjun Chen, NIDCR, National Institutes of Health, USA TGF-beta and Regulatory T Cells in Immune Responses and Inflammation
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 6 of 8 Bin Li, Shanghai Institute of Immunology, China Short Talk: Posttranslational Regulation of FOXP3 and Treg Stability Under Inflammation
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 7 of 8 Yisong Wan, University of North Carolina at Chapel Hill, USA Short Talk: An Unexpected Essential Function of Smad4 for T Cell Function and Autoimmunity
Sunday, January 19 \| 8:30AM - 12:00PM T Cells in Inflammatory Diseases Room: Columbia Ballroom Speaker 8 of 8 Xi Yang, University of Pittsburgh, USA Short Talk: ATF4 Is Induced by ROS and Regulates Th1 and Th17 Responses
Sunday, January 19 \| 8:30AM - 11:30AM Initial Cellular Sensors of Stress and Injury This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 5 * Hergen Spits, University of Amsterdam, Netherlands
Sunday, January 19 \| 8:30AM - 11:30AM Initial Cellular Sensors of Stress and Injury This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 5 Richard M. Locksley, HHMI/University of California, San Francisco, USA Cytokine Networks in Type 2 Immunity
Sunday, January 19 \| 8:30AM - 11:30AM Initial Cellular Sensors of Stress and Injury This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 5 Gabriel Nuñez, University of Michigan, USA Pathogen Colonization and Allergic Skin Disease
Sunday, January 19 \| 8:30AM - 11:30AM Initial Cellular Sensors of Stress and Injury This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 5 Andreas Diefenbach, Charité – Universitätsmedizin Berlin, Germany Transcriptional Regulation of ILC Subsets
Sunday, January 19 \| 8:30AM - 11:30AM Initial Cellular Sensors of Stress and Injury This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 5 Marco Colonna, Washington University School of Medicine, USA Regulation of ILC and NK Subsets
Sunday, January 19 \| 9:50AM - 10:10AM Coffee Break Room: British/Columbia Foyer
Sunday, January 19 \| 12:00PM - 1:00PM Lunch Room: Pacific Ballroom
Sunday, January 19 \| 12:30PM - 3:00PM Poster Session 2 Room: Pacific Ballroom
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 9 * Marc Veldhoen, Faculdade de Medicina da Universidade de Lisboa Avenida, Portugal
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 9 Sylvia Cheung, University of British Columbia, Canada Interleukin-10 Triggers Rapid Anti-Inflammatory Responses through SHIP1
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 9 Sarah L. Gaffen, University of Pittsburgh, USA Feedback Inhibition of IL-17 Signal Transduction by A20/TNFAIP3 and the Anaphase Promoting Complex Protein 5
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 9 Heth R. Turnquist, University of Pittsburgh, USA IL-33 Promotes Dendritic Cell Expansion of a Distinct Foxp3+ Treg Subset Suppressing Type 1 Immunity
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 9 Matthew R. Hepworth, Institute of Immunology, USA Innate Lymphoid Cells Regulate CD4+ T Cell Responses to Commensal Bacteria via MHCII
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 6 of 9 Marina Saresella, Fondazione don C. Gnocchi IRCCS ONLUS, Italy Toll-Like Receptor 3 Differently Modulates Inflammation in Progressive or Benign Multiple Sclerosis
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 7 of 9 Peter Tougaard, University of Copenhagen, Denmark The Impact of the Cytokine TL1A on Gut Homeostasis in Mice
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 8 of 9 Jan-Eric Turner, Universitätsklinikum Hamburg-Eppendorf, Germany IL-9-Mediated Survival of Type 2 Innate Lymphoid Cells Promotes Damage Control in Helminth-Induced Lung Inflammation
Sunday, January 19 \| 2:30PM - 4:30PM Workshop 2 This session is from Emerging Cytokines Room: British Ballroom Speaker 9 of 9 Estefania Claudio, NIAID, National Institutes of Health, USA IL-25-Mediated Activation of Lung Dendritic Cells Is Central to House Dust Mite-Induced Generation of Th9 Cells and Airway Remodeling
Sunday, January 19 \| 4:30PM - 5:00PM Coffee Available Room: British/Columbia Foyer
Sunday, January 19 \| 5:00PM - 7:15PM Treatments with Small Molecules Room: Columbia Ballroom Speaker 1 of 5 * Virginia Pascual, Cornell University, USA
Sunday, January 19 \| 5:00PM - 7:15PM Treatments with Small Molecules Room: Columbia Ballroom Speaker 2 of 5 Andreas Billich, Novartis Institutes for BioMedical Research, Switzerland Fingolimod/FTY720 (Gilenya) in the Treatment of Multiple Sclerosis: Mode-of-Action and Clinical Experience
Sunday, January 19 \| 5:00PM - 7:15PM Treatments with Small Molecules Room: Columbia Ballroom Speaker 3 of 5 John Bertin, GlaxoSmithKline, USA Therapeutic Targeting of RIP1 Kinase and Necroptosis
Sunday, January 19 \| 5:00PM - 7:15PM Treatments with Small Molecules Room: Columbia Ballroom Speaker 4 of 5 Vanessa C. Taylor, Rigel Inc., USA Short Talk: Novel Small Molecule Inhibitors of Interleukin-1 Receptor Associated Kinase-1 and -4 (IRAK-1 and IRAK-4) Identified by Cell-Based Screening Are Effective in Rodent Models of Inflammation
Sunday, January 19 \| 5:00PM - 7:15PM Treatments with Small Molecules Room: Columbia Ballroom Speaker 5 of 5 Gordon Alton, Visionary Pharmaceuticals, USA Short Talk: RORgt Inverse Agonists for the Treatment of Inflammatory Bowel Disease
Sunday, January 19 \| 5:00PM - 7:00PM Cytokine Networks at Barrier Surfaces This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 5 * Sarah L. Gaffen, University of Pittsburgh, USA
Sunday, January 19 \| 5:00PM - 7:00PM Cytokine Networks at Barrier Surfaces This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 5 Jason G. Cyster, HHMI/University of California, San Francisco, USA EBI2 and Oxysterols in Immune Cell Guidance and Regulation
Sunday, January 19 \| 5:00PM - 7:00PM Cytokine Networks at Barrier Surfaces This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 5 Fumio Takei, University of British Columbia and BC Cancer Agency, Canada Cytokine Regulation of ILC2, Th2 Cells and Allergic Lung Inflammation
Sunday, January 19 \| 5:00PM - 7:00PM Cytokine Networks at Barrier Surfaces This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 5 Jay K. Kolls, Tulane School of Medicine, USA Adaptive and Innate Response in Respiratory Infection
Sunday, January 19 \| 5:00PM - 7:00PM Cytokine Networks at Barrier Surfaces This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 5 Jose Ordovas-Montanes, Boston Children's Hospital and Harvard Medical School, USA Short Talk: Sensory Nerve Fibers Drive Interleukin-23 Mediated Psoriasis-Like Skin Inflammation
Sunday, January 19 \| 7:15PM - 7:15PM On Own for Dinner
Monday, January 20 \| 7:30AM - 8:30AM Breakfast Room: Pacific Ballroom
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 1 of 8 * Shimon Sakaguchi, Osaka University, Japan
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 2 of 8 David A. Hafler, Yale University School of Medicine, USA From Genetics to Immune Targets
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 3 of 8 Virginia Pascual, Cornell University, USA Systemic Approaches in Systemic Disease
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 4 of 8 Farrah Kheradmand, Baylor College of Medicine, USA Smoke-Induced Reduction of PPAR-gamma Drives Emphysema
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 5 of 8 Howard L. Weiner, Brigham and Women’s Hospital, Harvard Medical School, USA Treatment of Inflammatory and Autoimmune Diseases by Mucosal Induction of Regulatory T Cells
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 6 of 8 Bryan J. Vander Lugt, Genentech, Inc., USA Short Talk: Transcriptional Programming of Dendritic Cells for Priming Immunogenic and Tolerogenic MHCII-Restricted T Cell Responses
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 7 of 8 Andrew P. Fontenot, University of Colorado Denver, USA Short Talk: Regulatory T Cells Modulate Granulomatous Inflammation in an HLA-DP2 Transgenic Murine Model of Beryllium-Induced Disease
Monday, January 20 \| 8:30AM - 12:00PM Translational Research Room: Columbia Ballroom Speaker 8 of 8 Colby Zaph, Monash University, Australia Short Talk: Epigenetic Regulation of ILC2 Development and Function
Monday, January 20 \| 8:30AM - 11:30AM Environmental Factors that Influence Immunity This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 6 * Jay K. Kolls, Tulane School of Medicine, USA
Monday, January 20 \| 8:30AM - 11:30AM Environmental Factors that Influence Immunity This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 6 Max D. Cooper, Emory University, USA Comparative Analysis of Alternative Adaptive Immune Systems
Monday, January 20 \| 8:30AM - 11:30AM Environmental Factors that Influence Immunity This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 6 Marc Veldhoen, Faculdade de Medicina da Universidade de Lisboa Avenida, Portugal EMBO Young Investigator Lecture: Influence of Environmental Factors on Lymphocyte Biology
Monday, January 20 \| 8:30AM - 11:30AM Environmental Factors that Influence Immunity This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 6 Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA Unexpected Targets and Triggers of Autoimmunity
Monday, January 20 \| 8:30AM - 11:30AM Environmental Factors that Influence Immunity This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 6 Federica Sallusto, Università della Svizzera Italiana & ETH Zurich, Switzerland Cytokine Regulation of Human T Cell Subsets
Monday, January 20 \| 8:30AM - 11:30AM Environmental Factors that Influence Immunity This session is from Emerging Cytokines Room: British Ballroom Speaker 6 of 6 Parizad Torabi-Parizi, National Institutes of Health, USA Short Talk: Imaging-Based Insights into Effector CD4+ T Cell Behavior in Peripheral Tissues
Monday, January 20 \| 9:50AM - 10:10AM Coffee Break Room: British/Columbia Foyer
Monday, January 20 \| 12:00PM - 1:00PM Poster Setup Room: Pacific Ballroom
Monday, January 20 \| 12:00PM - 5:00PM On Own for Lunch and Recreation
Monday, January 20 \| 1:00PM - 10:00PM Poster Viewing Room: Pacific Ballroom
Monday, January 20 \| 4:30PM - 5:00PM Coffee Available Room: British/Columbia Foyer
Monday, January 20 \| 5:00PM - 7:15PM Inflammation and Cancer Room: Columbia Ballroom Speaker 1 of 6 * Yisong Wan, University of North Carolina at Chapel Hill, USA
Monday, January 20 \| 5:00PM - 7:15PM Inflammation and Cancer Room: Columbia Ballroom Speaker 2 of 6 Michael Karin, University of California, San Diego, USA Liver Inflammation and Cancer
Monday, January 20 \| 5:00PM - 7:15PM Inflammation and Cancer Room: Columbia Ballroom Speaker 3 of 6 Raymond N. DuBois, Arizona State University, USA The Role of Inflammation and Inflammatory Mediators in Progression of Colorectal Cancer
Monday, January 20 \| 5:00PM - 7:15PM Inflammation and Cancer Room: Columbia Ballroom Speaker 4 of 6 Lisa M. Coussens, Oregon Health & Science University, USA Inflammation and Cancer: Immune Cells as Targets for Anti-Cancer Therapy
Monday, January 20 \| 5:00PM - 7:15PM Inflammation and Cancer Room: Columbia Ballroom Speaker 5 of 6 Sacha J. Holland, Rigel, Inc., USA Short Talk: Protein Kinase C (PKC) Family Inhibitor R896 and PKC-theta-Selective Inhibitor R683 Block T Cell Activation and Suppress Immune-Mediated Disease in Rodents
Monday, January 20 \| 5:00PM - 7:15PM Inflammation and Cancer Room: Columbia Ballroom Speaker 6 of 6 Shu-Hsia Chen, Mount Sinai School of Medicine, USA Short Talk: CMTM4, a Novel Chemokine Regulator that Controls Inflammatory Responses in Tumor Microenvironment
Monday, January 20 \| 5:00PM - 7:00PM Cellular Intrinsic Factors that Influence Cytokine Responses This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 5 * Yasmine Belkaid, NIAID, National Institutes of Health, USA
Monday, January 20 \| 5:00PM - 7:00PM Cellular Intrinsic Factors that Influence Cytokine Responses This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 5 Fan Pan, Johns Hopkins University School of Medicine, USA Hypoxia Response and Th17 Regulation
Monday, January 20 \| 5:00PM - 7:00PM Cellular Intrinsic Factors that Influence Cytokine Responses This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 5 Silvia Monticelli, Institute for Research in Biomedicine, Switzerland Regulation of IL-17 Production in Recently Activated Human Th17 Cells
Monday, January 20 \| 5:00PM - 7:00PM Cellular Intrinsic Factors that Influence Cytokine Responses This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 5 K. Mark Ansel, University of California, San Francisco, USA MicroRNA Regulation in Immunity
Monday, January 20 \| 5:00PM - 7:00PM Cellular Intrinsic Factors that Influence Cytokine Responses This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 5 Kiyoshi Hirahara, Graduate School of Medicine, Chiba University, Japan Short Talk: Asymmetry of STAT Action to Define Specificity and Redundancy of IL-27 and IL-6 Signals
Monday, January 20 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Pacific Ballroom
Monday, January 20 \| 7:30PM - 10:00PM Poster Session 3 Room: Pacific Ballroom
Tuesday, January 21 \| 7:30AM - 8:30AM Breakfast Room: Pacific Ballroom
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 1 of 7 * Vijay K. Kuchroo, Brigham and Women's Hospital, Harvard Medical School, USA
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 2 of 7 Tadamitsu Kishimoto, Osaka University, Japan IL-6: A Balance between Arid5a and Regnase-1 in Autoimmune Inflammatory Disease
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 3 of 7 Dhavalkumar D. Patel, UCB S.A., Belgium Treatment of Inflammatory Diseases with Anti-IL17
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 4 of 7 Daniel J. Cua, Janssen Pharmaceutical Companies of Johnson & Johnson, USA Targeting IL-23 in Inflammatory Disorders
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 5 of 7 Ira Mellman, Genentech, Inc., USA Targeting the PD1/PDL1 Axis for Cancer Immunotherapy Alone and in Combination
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 6 of 7 Fabian Buller, Neurimmune AG, Switzerland Short Talk: COVA322: A Novel, Bispecific TNF/IL-17A Inhibitor for the Treatment of Inflammatory Diseases Moving toward the Clinic
Tuesday, January 21 \| 8:30AM - 11:45AM Targeting Immune Modulators in Autoimmunity and Cancer (Join t) Room: British/Columbia Ballroom Speaker 7 of 7 Daniel Hawiger, St. Louis University, USA Short Talk: Long-Lasting Immune Tolerance Mediated by Dendritic Cells Depends on Functions of Homeodomain Only Protein (Hopx) in Peripherally Induced Regulatory T Cells
Tuesday, January 21 \| 9:50AM - 10:10AM Coffee Break Room: British/Columbia Foyer
Tuesday, January 21 \| 11:45AM - 5:00PM On Own for Lunch and Recreation
Tuesday, January 21 \| 4:30PM - 5:00PM Coffee Available Room: British/Columbia Foyer
Tuesday, January 21 \| 5:00PM - 7:15PM Immune Tolerance Re-Establishment Room: Columbia Ballroom Speaker 1 of 6 * Wanjun Chen, NIDCR, National Institutes of Health, USA
Tuesday, January 21 \| 5:00PM - 7:15PM Immune Tolerance Re-Establishment Room: Columbia Ballroom Speaker 2 of 6 Jeffrey A. Bluestone, University of California, San Francisco, USA Anti-CD3, Tregs and Treg-Friendly Therapeutics to Induce Tolerance
Tuesday, January 21 \| 5:00PM - 7:15PM Immune Tolerance Re-Establishment Room: Columbia Ballroom Speaker 3 of 6 Bruce R. Blazar, University of Minnesota, USA The Use of ex vivo Expanded Regulatory T Cells (Tregs) for the Prevention of Graft-versus-Host Disease (GVHD)
Tuesday, January 21 \| 5:00PM - 7:15PM Immune Tolerance Re-Establishment Room: Columbia Ballroom Speaker 4 of 6 Stephen D. Miller, Northwestern University Medical School, USA MARCO-Targeting Carboxylated PLG Nanoparticles Promote Tolerance Induction and Suppression of Inflammatory Monocytes
Tuesday, January 21 \| 5:00PM - 7:15PM Immune Tolerance Re-Establishment Room: Columbia Ballroom Speaker 5 of 6 Hazel Claire Poyntz, Malaghan Institute of Medical Research, New Zealand Short Talk: Intestinal Microbial Composition as Immunotherapy for Allergy Prevention
Tuesday, January 21 \| 5:00PM - 7:15PM Immune Tolerance Re-Establishment Room: Columbia Ballroom Speaker 6 of 6 Helena Kiefel, Second Genome, Inc., USA Short Talk: Intestinal T Cell Expression of a G-Protein-Coupled Receptor for Short Chain Fatty Acids: Role in T Cell Homeostasis and Colitis
Tuesday, January 21 \| 5:00PM - 7:00PM Clinical Application of Immune Modulators This session is from Emerging Cytokines Room: British Ballroom Speaker 1 of 5 * Silvia Monticelli, Institute for Research in Biomedicine, Switzerland
Tuesday, January 21 \| 5:00PM - 7:00PM Clinical Application of Immune Modulators This session is from Emerging Cytokines Room: British Ballroom Speaker 2 of 5 John J. O'Shea, NIAMS, National Institutes of Health, USA Targeting Cytokine Signaling: That's a Fact, Jak
Tuesday, January 21 \| 5:00PM - 7:00PM Clinical Application of Immune Modulators This session is from Emerging Cytokines Room: British Ballroom Speaker 3 of 5 Adrian C. Hayday, King's College London School of Medicine, UK The Contribution of gamma delta T Cells to Afferent Immunogenicity in Mice and in the Clinic
Tuesday, January 21 \| 5:00PM - 7:00PM Clinical Application of Immune Modulators This session is from Emerging Cytokines Room: British Ballroom Speaker 4 of 5 Maria Grazia Roncarolo, Stanford University School of Medicine, USA Cell-Based Immune Therapy for Tolerance Induction
Tuesday, January 21 \| 5:00PM - 7:00PM Clinical Application of Immune Modulators This session is from Emerging Cytokines Room: British Ballroom Speaker 5 of 5 Hosahalli Subramanya, Aurigene Discovery Technologies Ltd., India Short Talk: Efficacy of Novel and Selective RORgamma Inverse Agonists in Psoriasis and Asthma Models
Tuesday, January 21 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Pacific Ballroom
Tuesday, January 21 \| 8:00PM - 11:00PM Entertainment Room: Pacific Ballroom
Tuesday, January 21 \| 8:00PM - 11:00PM Cash Bar Room: Pacific Ballroom
Wednesday, January 22 \| 10:25AM - 10:25AM Departure *Session Chair.