Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
	The Global Virome in Health and Disease (2020C1)
Viral Immunity: Mechanisms and Consequences (2017B4)
Viral Immunity (2015A2)

Web Desc
Pathogenesis of Respiratory Viruses joint with Innate Immunity to Viral Infections Organizer(s): Adolfo García-Sastre and Peter J.M. Openshaw Date: January 19 - 24, 2014 Location: Keystone Resort, Keystone, CO, USA Sponsored by AstraZeneca Summary of Meeting: Respiratory viruses are a major cause of infectious disease and death in humans. The Keystone Symposia meeting on 'Pathogenesis of Respiratory Viruses' will discuss some of the latest advances in our understanding of the biology and pathogenesis of this group of viruses, including major human pathogens such as influenza viruses, respiratory syncytial virus, parainfluenza virus, rhinoviruses, coronaviruses and adenoviruses. There will be a special emphasis on influenza and respiratory syncytial virus. This meeting will bring together experts in virology, viral pathogenesis and viral immunity to discuss factors contributing to viral replication, tropism, disease and immunity in the respiratory tract. Opportunities for synergistic interactions will be significantly enhanced by the concurrent meeting on 'Innate Immunity to Viral Infections,' resulting in a more integrated view of viral disease and immunity. Scholarship Deadline: October 9 2013 Discounted Abstract Deadline: October 9 2013 Abstract Deadline: October 31 2013 Discounted Registration Deadline: November 19 2013 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Novartis Institutes for BioMedical Research We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI110083-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Pathogenesis of Respiratory Viruses

joint with Innate Immunity to Viral Infections

Organizer(s): Adolfo García-Sastre and Peter J.M. Openshaw

Date: January 19 - 24, 2014
Location: Keystone Resort, Keystone, CO, USA

Program


Sunday, January 19 \| 4:00PM - 8:00PM Arrival and Registration Room: Longs Peak Foyer
Monday, January 20 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud/Shavano
Monday, January 20 \| 8:00AM - 10:00AM Keynote Session (Joint) Room: Columbine Ballroom Speaker 1 of 3 * Adolfo García-Sastre, Mount Sinai School of Medicine, USA
Monday, January 20 \| 8:00AM - 10:00AM Keynote Session (Joint) Room: Columbine Ballroom Speaker 2 of 3 * Caetano Reis e Sousa, Francis Crick Institute, UK RLRs in Immunity to Viruses
Monday, January 20 \| 8:00AM - 10:00AM Keynote Session (Joint) Room: Columbine Ballroom Speaker 3 of 3 Peter M. Palese, Icahn School of Medicine at Mount Sinai, USA Why Do Influenza Viruses Undergo Antigenic Drift and Shift and What Can We Do About It?
Monday, January 20 \| 10:00AM - 10:20AM Coffee Break Room: Longs Peak Foyer
Monday, January 20 \| 10:20AM - 12:00PM Viral Entry and Replication Room: Quandary Peak Glycoprotein structure, viral entry and genome replication. Speaker 1 of 4 * Yoshihiro Kawaoka, University of Wisconsin / University of Tokyo, USA
Monday, January 20 \| 10:20AM - 12:00PM Viral Entry and Replication Room: Quandary Peak Glycoprotein structure, viral entry and genome replication. Speaker 2 of 4 Ian A. Wilson, The Scripps Research Institute, USA Structural Basis of Influenza HA Function and Neutralization
Monday, January 20 \| 10:20AM - 12:00PM Viral Entry and Replication Room: Quandary Peak Glycoprotein structure, viral entry and genome replication. Speaker 3 of 4 James E. Crowe, Jr., Vanderbilt University Medical Center, USA Host-Virus Interactions during RSV Infection
Monday, January 20 \| 10:20AM - 12:00PM Viral Entry and Replication Room: Quandary Peak Glycoprotein structure, viral entry and genome replication. Speaker 4 of 4 Robert A. Lamb, Northwestern University, USA The Mechanism of Entry into Cells by Membrane Fusion for Respiratory Negative Strand Viruses
Monday, January 20 \| 10:20AM - 12:00PM Antiviral Strategies Across Taxa This session is from Innate Immunity Room: Longs/Grays Peaks Virus defense strategies in bacteria, plants and invertebrates, CRISPR RNAs, RNAi, death. Speaker 1 of 4 * Sara R. Cherry, University of Pennsylvania, USA
Monday, January 20 \| 10:20AM - 12:00PM Antiviral Strategies Across Taxa This session is from Innate Immunity Room: Longs/Grays Peaks Virus defense strategies in bacteria, plants and invertebrates, CRISPR RNAs, RNAi, death. Speaker 2 of 4 Luciano A. Marraffini, Rockefeller University, USA Tolerance during CRISPR-Cas Immunity: Domesticating the Virus
Monday, January 20 \| 10:20AM - 12:00PM Antiviral Strategies Across Taxa This session is from Innate Immunity Room: Longs/Grays Peaks Virus defense strategies in bacteria, plants and invertebrates, CRISPR RNAs, RNAi, death. Speaker 3 of 4 Jean-Luc Imler, Institut de Biologie Moléculaire et Cellulaire, France Sensing and Signaling Viral Infection in Drosophila
Monday, January 20 \| 10:20AM - 12:00PM Antiviral Strategies Across Taxa This session is from Innate Immunity Room: Longs/Grays Peaks Virus defense strategies in bacteria, plants and invertebrates, CRISPR RNAs, RNAi, death. Speaker 4 of 4 Shou-Wei Ding, University of California, Riverside, USA RNAi as an Antiviral Strategy across Species, including Vertebrates
Monday, January 20 \| 12:00PM - 1:00PM Poster Setup Room: Crestone/Red Cloud/Shavano
Monday, January 20 \| 12:00PM - 2:30PM On Own for Lunch and Recreation
Monday, January 20 \| 1:00PM - 10:00PM Poster Viewing Room: Crestone/Red Cloud/Shavano
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 1 of 10 * James E. Crowe, Jr., Vanderbilt University Medical Center, USA
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 2 of 10 * Cecilia Johansson, Imperial College London, UK
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 3 of 10 Victor Stalinraj, Erasmus Medical Center, Netherlands Characterization of DPP4 as the Functional Receptor for Middle East Respiratory Syndrome Coronavirus
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 4 of 10 Monika Bajorek, Imperial College London, UK Human RSV M Protein Interactions with Host Proteins Reveal New Cellular Ligands Involved in Viral Nuclear Localization and Innate Defense
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 5 of 10 Kavestri Yegambaram, University of Auckland, New Zealand Protein Interactions Underpinning Movement of the Viral Polymerase Diverge in the Paramyxovirinae
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 6 of 10 Patricia S. Domingues, University of Glasgow, UK Non-Canonical Interplay between Influenza Virus and the Host SUMO System
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 7 of 10 Raymond J. Pickles, University of North Carolina, Chapel Hill, USA Respiratory Syncytial Virus NS2 Protein Promotes Shedding of Virus-Infected Epithelial Cells Resulting in Acute Distal Airway Obstruction
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 8 of 10 Christopher Brooke, NIAID, National Institutes of Health, USA Illuminating the Dark Matter of Influenza A Virus Infection: Dynamic Viral Gene Expression Patterns within the “Non-Infectious” Virus Population
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 9 of 10 Nicholas S. Heaton, Icahn School of Medicine at Mount Sinai, USA Genome-Wide Mutagenesis of Influenza Virus: Unique Plasticity of the Hemagglutinin and NS1 Proteins
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Virus-Host Interactions Room: Quandary Peak Speaker 10 of 10 Hugh D. Mitchell, Pacific Northwest National Laboratory, USA Integration of Proteomics Data Focuses Pathogenicity Pathways from Influenza Infection
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 1 of 8 * John Hiscott, Vaccine & Gene Therapy Institute of Florida, USA
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 2 of 8 David E. Levy, New York University School of Medicine, USA Regulation of IFN Production and Response during Viral Infections
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 3 of 8 Eva-Katharina Pauli, Boston College, USA USP15 Promotes RIG-I Antiviral Signaling by Stabilizing TRIM25
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 4 of 8 Sun Hur, Harvard Medical School, USA RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent and Ubiquitin-Independent Manner
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 5 of 8 Hao-Sen Chiang, National Taiwan University, Taiwan GEF-H1 Mediates Microtubule-Dependent Sensing of Nucleic Acids for Antiviral Host Defenses
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 6 of 8 Chen Seng Ng, Kyoto University, Japan Encephalomyocarditis Virus Disrupts Stress Granules, the Critical Platform for Triggering Antiviral Innate Immune Responses
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 7 of 8 Søren Riis Paludan, University of Aarhus, Denmark Gammaherpesviruses Evade Innate Immune Activation via Cytosolic DNA Sensors to Allow Establishment of Chronic Infection
Monday, January 20 \| 2:30PM - 4:30PM Workshop 1: Innate Virus Sensors This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 8 of 8 Pingwei Li, Texas A&M University, USA Cyclic GMP-AMP Synthase is Activated by Double-Stranded DNA- Induced Oligomerization
Monday, January 20 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Monday, January 20 \| 5:00PM - 7:00PM Virus-Host Interactions Room: Quandary Peak Host factors required for replication, impact of viral infection in cell functions. Speaker 1 of 5 * Tracy Hussell, University of Manchester, UK
Monday, January 20 \| 5:00PM - 7:00PM Virus-Host Interactions Room: Quandary Peak Host factors required for replication, impact of viral infection in cell functions. Speaker 2 of 5 Yoshihiro Kawaoka, University of Wisconsin / University of Tokyo, USA Influenza Virus Pathogenesis and Transmission
Monday, January 20 \| 5:00PM - 7:00PM Virus-Host Interactions Room: Quandary Peak Host factors required for replication, impact of viral infection in cell functions. Speaker 3 of 5 Ursula J. Buchholz, NIAID, National Institutes of Health, USA Evasion of the Adaptive Immune Response by HRSV and HMPV
Monday, January 20 \| 5:00PM - 7:00PM Virus-Host Interactions Room: Quandary Peak Host factors required for replication, impact of viral infection in cell functions. Speaker 4 of 5 J. Kenneth Baillie, University of Edinburgh, UK Host Genetic Susceptibility and Viral Pathogenesis
Monday, January 20 \| 5:00PM - 7:00PM Virus-Host Interactions Room: Quandary Peak Host factors required for replication, impact of viral infection in cell functions. Speaker 5 of 5 Sharon K. Kuss, University of Texas Southwestern Medical Center, USA Short Talk: Influenza A Virus RNA Splicing is Regulated by Cellular Proteins NS1-BP and hnRNP K
Monday, January 20 \| 5:00PM - 7:00PM Effector Responses and Viral Evasion This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 1 of 5 * Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA
Monday, January 20 \| 5:00PM - 7:00PM Effector Responses and Viral Evasion This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 2 of 5 Sara R. Cherry, University of Pennsylvania, USA Autophagy Nutrient Signaling and Antiviral Defenses
Monday, January 20 \| 5:00PM - 7:00PM Effector Responses and Viral Evasion This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 3 of 5 Kanako Kuniyoshi, iOsaka University, Japan Short Talk: Pivotal Role of RNA-Binding E3 Ubiquitin Ligase Mex3c in RIG-I-Mediated Antiviral Innate Immunity
Monday, January 20 \| 5:00PM - 7:00PM Effector Responses and Viral Evasion This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 4 of 5 Michael Gale, Jr., University of Washington, USA Differential Innate Antiviral Effector Responses Impart Outcome of Pathogenic and Nonpathogenic Flavivirus Infection
Monday, January 20 \| 5:00PM - 7:00PM Effector Responses and Viral Evasion This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 5 of 5 Andrew G. Bowie, Trinity College Dublin, Ireland Unexpected Roles for the TLR Adaptors TRAM and SARM in Anti-Viral Gene Induction
Monday, January 20 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud/Shavano
Monday, January 20 \| 7:30PM - 10:00PM Poster Session 1 Room: Crestone/Red Cloud/Shavano
Tuesday, January 21 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud/Shavano
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 1 of 7 * Charles M. Rice, Rockefeller University, USA
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 2 of 7 Teunis B.H. Geijtenbeek, University of Amsterdam, Netherlands C-Type Lectin Receptors as Virus Sensors or ‘Dupes’
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 3 of 7 Kate A. Fitzgerald, University of Massachusetts Medical School, USA Long Non-Coding RNA and Innate Immunity
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 4 of 7 Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA Innate Immune Sensing of Cytosolic DNA
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 5 of 7 Juris A. Grasis, San Diego State University, USA Short Talk: Viral Recognition in the Basal Metazoan Hydra
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 6 of 7 Akshay A. D'Cruz, Walter and Eliza Hall Institute of Medical Research, Australia Short Talk: A Two-Site Interaction Underpins TRIM25 Activation of the RIG-I Anti-Viral Response
Tuesday, January 21 \| 8:00AM - 11:15AM Virus Detection by the Host (Joint) Room: Columbine Ballroom Cell-intrinsic (RLRs, DNA sensors), cell-extrinsic (TLRs, CLRs). Speaker 7 of 7 Karl-Peter Hopfner, Ludwig-Maximilians-University Munich, Germany Talk Title to be Announced
Tuesday, January 21 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Tuesday, January 21 \| 11:15AM - 1:00PM Poster Setup Room: Crestone/Red Cloud/Shavano
Tuesday, January 21 \| 11:15AM - 5:00PM On Own for Lunch and Recreation
Tuesday, January 21 \| 1:00PM - 10:00PM Poster Viewing Room: Crestone/Red Cloud/Shavano
Tuesday, January 21 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Tuesday, January 21 \| 5:00PM - 7:00PM Innate Immunity in Pathogenesis Room: Quandary Peak Speaker 1 of 6 * Adolfo García-Sastre, Mount Sinai School of Medicine, USA
Tuesday, January 21 \| 5:00PM - 7:00PM Innate Immunity in Pathogenesis Room: Quandary Peak Speaker 2 of 6 * Ben Hale, University of Glasgow, UK
Tuesday, January 21 \| 5:00PM - 7:00PM Innate Immunity in Pathogenesis Room: Quandary Peak Speaker 3 of 6 Peter Staeheli, University of Freiburg, Germany Role of Interferon in Influenza Virus Defense
Tuesday, January 21 \| 5:00PM - 7:00PM Innate Immunity in Pathogenesis Room: Quandary Peak Speaker 4 of 6 Cecilia Johansson, Imperial College London, UK Interferon Responses to Respiratory Syncytial Virus (RSV) Infection
Tuesday, January 21 \| 5:00PM - 7:00PM Innate Immunity in Pathogenesis Room: Quandary Peak Speaker 5 of 6 Deborah J. Lenschow, Washington University School of Medicine, USA Regulation of the Host Response to Viral Infection by ISG15
Tuesday, January 21 \| 5:00PM - 7:00PM Innate Immunity in Pathogenesis Room: Quandary Peak Speaker 6 of 6 Amy C. Graham, Montana State University, USA Short Talk: Influenza A Virus Activates Mast Cells to Enhance Viral-Induced Pathology
Tuesday, January 21 \| 5:00PM - 7:00PM Signaling Responses to Virus Infection This session is from Innate Immunity Room: Longs/Grays Peaks MAVS, STING, inflammasome. Speaker 1 of 5 * Andrew G. Bowie, Trinity College Dublin, Ireland
Tuesday, January 21 \| 5:00PM - 7:00PM Signaling Responses to Virus Infection This session is from Innate Immunity Room: Longs/Grays Peaks MAVS, STING, inflammasome. Speaker 2 of 5 Yong-Jun Liu, Sanofi, USA Biochemical Characterization of Nucleic Acid Sensors in Dendritic Cells
Tuesday, January 21 \| 5:00PM - 7:00PM Signaling Responses to Virus Infection This session is from Innate Immunity Room: Longs/Grays Peaks MAVS, STING, inflammasome. Speaker 3 of 5 Kate L. Jeffrey, Harvard Medical School, USA Short Talk: Antiviral Defense in Mammals Mediated by Argonautes 2 and 4
Tuesday, January 21 \| 5:00PM - 7:00PM Signaling Responses to Virus Infection This session is from Innate Immunity Room: Longs/Grays Peaks MAVS, STING, inflammasome. Speaker 4 of 5 Glen N. Barber, University of Miami, USA STING at the Crossroads of Cell-Intrinsic DNA Sensing
Tuesday, January 21 \| 5:00PM - 7:00PM Signaling Responses to Virus Infection This session is from Innate Immunity Room: Longs/Grays Peaks MAVS, STING, inflammasome. Speaker 5 of 5 Veit Hornung, Ludwig-Maximilians-University Munich, Germany Spreading of Antiviral Immunity via Gap Junctions
Tuesday, January 21 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud/Shavano
Tuesday, January 21 \| 7:30PM - 10:00PM Poster Session 2 Room: Crestone/Red Cloud/Shavano
Wednesday, January 22 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud/Shavano
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 1 of 7 * Peter J.M. Openshaw, Imperial College London, UK
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 2 of 7 Tracy Hussell, University of Manchester, UK Airway Immune Homeostasis
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 3 of 7 Andreas Wack, Francis Crick Institute, UK Short Talk: Interferon in Flu
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 4 of 7 Ricardo Rajsbaum, University of Texas Medical Branch, USA Short Talk: Activation of Ikk Epsilon
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 5 of 7 Harry B. Greenberg, Stanford University, USA Rotaviruses and Vaccines: Host Range, Pathogenesis and Innate Immunity - A Ménage a Trois
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 6 of 7 Nicholas W. Lukacs, University of Michigan, USA Talk Title to be Announced
Wednesday, January 22 \| 8:00AM - 11:00AM Induction of Immunity at Epithelial Surfaces (Joint) Room: Columbine Ballroom Dendritic cells, innate responses in the lung, inflammation. Speaker 7 of 7 Akiko Iwasaki, HHMI/Yale University School of Medicine, USA Linking Innate Recognition of Viruses to Adaptive Immunity
Wednesday, January 22 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Wednesday, January 22 \| 11:00AM - 1:00PM Poster Setup Room: Crestone/Red Cloud/Shavano
Wednesday, January 22 \| 11:00AM - 2:30PM On Own for Lunch and Recreation
Wednesday, January 22 \| 1:00PM - 10:00PM Poster Viewing Room: Crestone/Red Cloud/Shavano
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 1 of 10 * Adolfo García-Sastre, Mount Sinai School of Medicine, USA
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 2 of 10 * Ursula J. Buchholz, NIAID, National Institutes of Health, USA
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 3 of 10 Bas Baaten, Sanford-Burnham-Prebys Medical Discovery Institute, USA Antiviral Immunity to Influenza Virus at the Aged Nasal Mucosa
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 4 of 10 Tim Beaumont, AIMM Therapeutics, Netherlands Human B Cells Specific for the RSV F Prefusion Protein are Highly Prevalent and Efficiently Reduce Respiratory Tract Infection by RSV
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 5 of 10 Emily A. Hemann, University of Washington, USA The Contribution of Direct Infection of Pulmonary Plasmacytoid Dendritic Cells to Robust CD8 T Cell Responses in the Lungs during Influenza A Virus Infection
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 6 of 10 Rebecca J. Ortiz Marty, Nationwide Children's Hospital Research Institute, USA Epitope Specificity and Function of T-Cell Responses during Acute RSV Bronchiolitis and Memory in Children and Adults
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 7 of 10 Saranya Sridhar, Imperial College, UK CD8+ T Cells Correlate with Protection against Symptomatic Illness Following Natural Pandemic Influenza Infection in Humans
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 8 of 10 Jeffrey C. Boyington, NIAID, National Institutes of Health, USA Rational Design of an Influenza Hemagglutinin Stem Immunogen Enables Elicitation of Stem-Directed Neutralizing Antibodies
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 9 of 10 Nicole L. Kallewaard, MedImmune, USA Characterization of Novel Human Monoclonal Antibodies that Neutralize all Influenza A Viruses
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Host Responses Room: Quandary Peak Speaker 10 of 10 M. Gordon Joyce, US Military HIV Research Program, USA Structure-Based Respiratory Syncytial Virus Vaccine Design
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 1 of 8 * Søren Riis Paludan, University of Aarhus, Denmark
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 2 of 8 Curt M. Horvath, Northwestern University, USA Genomic Analysis Reveals Novel Sites of Virus-Induced RNA Transcription
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 3 of 8 Saumendra N. Sarkar, University of Pittsburgh Cancer Institute, USA Mechanisms of Antiviral Activity of Human OASL
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 4 of 8 Jennifer H. Stuart, University of Cambridge, UK Dual Mechanisms of Inhibition of Interferon Responses by Vaccinia Virus Protein C6
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 5 of 8 John Hiscott, Vaccine & Gene Therapy Institute of Florida, USA Host Restriction Factor SAMHD1 Limits Human Retrovirus Infection of Monocytes via STING-Mediated Apoptosis
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 6 of 8 John W. Schoggins, University of Texas Southwestern Medical Center, USA Expression Screens Identify a Viral Bias in Interferon-Induced Effector Specificity and a Requirement for cGAS in Antiviral Immunity
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 7 of 8 Sumana Sanyal, University of Hong Kong, Hong Kong Viral Exploitation of Host Intracellular Trafficking Pathways upon Interferon Induction
Wednesday, January 22 \| 2:30PM - 4:30PM Workshop 2: Antiviral Strategies This session is from Innate Immunity Room: Longs/Grays Peaks Speaker 8 of 8 Silke Paust, Baylor College of Medicine, USA Vaccine Induced Memory NK Cells Protect from Lethal Influenza Infection
Wednesday, January 22 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Wednesday, January 22 \| 5:00PM - 7:00PM Specific Immunity: The Good and the Bad Room: Quandary Peak Speaker 1 of 5 * Kanta Subbarao, WHO Collaborating Centre for Reference and Research on Influenza, Australia
Wednesday, January 22 \| 5:00PM - 7:00PM Specific Immunity: The Good and the Bad Room: Quandary Peak Speaker 2 of 5 Peter J.M. Openshaw, Imperial College London, UK Immunity to Respiratory Syncytial Virus (RSV) Infection
Wednesday, January 22 \| 5:00PM - 7:00PM Specific Immunity: The Good and the Bad Room: Quandary Peak Speaker 3 of 5 Patrick C. Wilson, University of Chicago, USA Diversity Drives the Human B Cell Response to Influenza
Wednesday, January 22 \| 5:00PM - 7:00PM Specific Immunity: The Good and the Bad Room: Quandary Peak Speaker 4 of 5 Ethan C. Settembre, Novartis Vaccines, USA Improving the Global Influenza Vaccine System
Wednesday, January 22 \| 5:00PM - 7:00PM Specific Immunity: The Good and the Bad Room: Quandary Peak Speaker 5 of 5 Cory J. Knudson, University of Iowa, USA Short Talk: Memory CD8 T Cells Provide Protection against Respiratory Syncytial Virus Infection at the Cost of Severe Pulmonary Immunopathology
Wednesday, January 22 \| 5:00PM - 7:00PM Defense from Retroviruses This session is from Innate Immunity Room: Longs/Grays Peaks Cell-intrinsic barriers to exogenous retroviruses and endogenous retroelements (APOBECs, TRIMs, tetherin, TREX1, SAMHD1). Speaker 1 of 5 * Alexander Tarakhovsky, Rockefeller University, USA
Wednesday, January 22 \| 5:00PM - 7:00PM Defense from Retroviruses This session is from Innate Immunity Room: Longs/Grays Peaks Cell-intrinsic barriers to exogenous retroviruses and endogenous retroelements (APOBECs, TRIMs, tetherin, TREX1, SAMHD1). Speaker 2 of 5 Stephen P. Goff, Columbia University, USA Silencing of Retroviral DNAs in Embryonic Stem Cells: Transacting Proteins, Chromatin Modifications, and Timing
Wednesday, January 22 \| 5:00PM - 7:00PM Defense from Retroviruses This session is from Innate Immunity Room: Longs/Grays Peaks Cell-intrinsic barriers to exogenous retroviruses and endogenous retroelements (APOBECs, TRIMs, tetherin, TREX1, SAMHD1). Speaker 3 of 5 Maroof Hasan, Novartis Institutes for BioMedical Research, Switzerland Short Talk: Tail-Anchored TREX1 Prevents Liberation of Free Glycans with Immunogenic Potential through a DNase-Independent Function
Wednesday, January 22 \| 5:00PM - 7:00PM Defense from Retroviruses This session is from Innate Immunity Room: Longs/Grays Peaks Cell-intrinsic barriers to exogenous retroviruses and endogenous retroelements (APOBECs, TRIMs, tetherin, TREX1, SAMHD1). Speaker 4 of 5 Jan Rehwinkel, Weatherall Institute of Molecular Medicine, University of Oxford, UK Nucleotide Starvation: A SAMHD1-Dependent Strategy for Cell-Intrinsic Anti-Retroviral Defense
Wednesday, January 22 \| 5:00PM - 7:00PM Defense from Retroviruses This session is from Innate Immunity Room: Longs/Grays Peaks Cell-intrinsic barriers to exogenous retroviruses and endogenous retroelements (APOBECs, TRIMs, tetherin, TREX1, SAMHD1). Speaker 5 of 5 Jeremy Luban, University of Massachusetts Medical School, USA TRIM5 is an Innate Immune Sensor for the HIV-1 Capsid Protein Lattice
Wednesday, January 22 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud/Shavano
Wednesday, January 22 \| 7:30PM - 10:00PM Poster Session 3 Room: Crestone/Red Cloud/Shavano
Thursday, January 23 \| 7:00AM - 8:00AM Breakfast Room: Crestone/Red Cloud/Shavano
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 1 of 8 * Monika Bajorek, Imperial College London, UK
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 2 of 8 Adolfo García-Sastre, Mount Sinai School of Medicine, USA Subversion of Innate Pathways by Influenza Virus
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 3 of 8 * Thomas J. Braciale, University of Virginia, USA Respiratory Dendritic Cells in the Control of Anti-Viral Effector and Memory T Cell Responses
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 4 of 8 Jonathan A. McCullers, University of Tennessee Health Sciences Center, USA The Importance of Virus-Mediated Immune Dysfunction in Secondary Bacterial Pneumonia following Influenza
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 5 of 8 Lance K. Blevins, Wake Forest School of Medicine, USA Short Talk: Coinfection with S. Pneumoniae Results in Decreases in Both the Quality and Quantity of Influenza Specific CD8+ T Cells
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 6 of 8 Agnieszka Rynda-Apple, Montana State University, USA Short Talk: Regulation of IFN-? by IL-13 Dictates the Susceptibility to Secondary Post-Influenza MRSA Pneumonia
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 7 of 8 Charles J. Russell, St. Jude Children's Research Hospital, USA Short Talk: Dynamics of Primary Parainfluenza Virus Infection and Protection from Reinfection are Determined by the Mode of Transmission while Pathogenesis is Determined by Distinct Viral and Host Factors
Thursday, January 23 \| 8:00AM - 11:15AM Virulence and Coinfections Room: Quandary Peak Speaker 8 of 8 Denise E. de Almeida Nagata, University of Michigan, USA Short Talk: Epigenetic Control by TGFbeta1-Inducible SMYD3 H3K4 Methyltransferase Influences iTreg Development and Respiratory Syncytial Virus-Related Disease Progression
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 1 of 7 * Veit Hornung, Ludwig-Maximilians-University Munich, Germany
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 2 of 7 Alexander Tarakhovsky, Rockefeller University, USA Epigenetic Regulation of Antiviral Immunity
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 3 of 7 Andreas Pichlmair, Max-Planck Institute of Biochemistry, Germany Nucleic Acid Binding Proteins with Antiviral Properties
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 4 of 7 Maria-Carla Saleh, Institut Pasteur, France Short Talk: Evidence of Long-Lasting Antiviral Immunity in Insects
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 5 of 7 Charles M. Rice, Rockefeller University, USA Antiviral Activities of Interferon-Stimulated Genes
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 6 of 7 Sonja M. Best, NIAID, National Institutes of Health, USA Short Talk: The Mechanism of Type I Interferon Antagonism by NS5 from Encephalitic Flaviviruses, TBEV and WNV
Thursday, January 23 \| 8:00AM - 11:15AM IFNs and ISGs This session is from Innate Immunity Room: Longs/Grays Peaks Innate IFNs (a/b lambda) and their receptors, ISGs and their antiviral effects (mechanism of action, importance in infections, etc.) Speaker 7 of 7 Gaya K. Amarasinghe, Washington University in St. Louis, USA A Structural Element at the 5'-End of Viral RNA Antagonizes IFIT1-Mediated Cell-Intrinsic Immunity
Thursday, January 23 \| 9:20AM - 9:40AM Coffee Break Room: Longs Peak Foyer
Thursday, January 23 \| 11:15AM - 5:00PM On Own for Lunch and Recreation
Thursday, January 23 \| 4:30PM - 5:00PM Coffee Available Room: Longs Peak Foyer
Thursday, January 23 \| 5:00PM - 7:00PM Regulation and Resolution of Inflammation Room: Quandary Peak Immunoregulation, resolvins Speaker 1 of 5 * Peter J.M. Openshaw, Imperial College London, UK
Thursday, January 23 \| 5:00PM - 7:00PM Regulation and Resolution of Inflammation Room: Quandary Peak Immunoregulation, resolvins Speaker 2 of 5 Bali Pulendran, Stanford University School of Medicine, USA Systems Vaccinology: Enabling Rational Vaccine Design with Systems Biology
Thursday, January 23 \| 5:00PM - 7:00PM Regulation and Resolution of Inflammation Room: Quandary Peak Immunoregulation, resolvins Speaker 3 of 5 Bruce D. Levy, Brigham and Women's Hospital, USA Specialized Pro-Resolving Mediators Promote the Resolution of Pathogen-Mediated Inflammation
Thursday, January 23 \| 5:00PM - 7:00PM Regulation and Resolution of Inflammation Room: Quandary Peak Immunoregulation, resolvins Speaker 4 of 5 Luis Enjuanes, CNB-Spanish National Research Council, Spain MERS and SARS Pathogenesis and Vaccines
Thursday, January 23 \| 5:00PM - 7:00PM Regulation and Resolution of Inflammation Room: Quandary Peak Immunoregulation, resolvins Speaker 5 of 5 Ryan A. Langlois, University of Minnesota, USA Short Talk: Long-Term Influenza A Virus Infected Cells are Critical for Repair of Respiratory Damage
Thursday, January 23 \| 5:00PM - 7:00PM Antiviral Innate Immunity in Disease This session is from Innate Immunity Room: Longs/Grays Peaks Inflammation and immunopathology, interferonopathies (AGS, lupus). Speaker 1 of 5 * Caetano Reis e Sousa, Francis Crick Institute, UK
Thursday, January 23 \| 5:00PM - 7:00PM Antiviral Innate Immunity in Disease This session is from Innate Immunity Room: Longs/Grays Peaks Inflammation and immunopathology, interferonopathies (AGS, lupus). Speaker 2 of 5 Yanick Crow, University of Edinburgh, UK Human Type I Interferonopathies
Thursday, January 23 \| 5:00PM - 7:00PM Antiviral Innate Immunity in Disease This session is from Innate Immunity Room: Longs/Grays Peaks Inflammation and immunopathology, interferonopathies (AGS, lupus). Speaker 3 of 5 Carla V. Rothlin, Yale University, USA Negative Regulation of Type I Interferons
Thursday, January 23 \| 5:00PM - 7:00PM Antiviral Innate Immunity in Disease This session is from Innate Immunity Room: Longs/Grays Peaks Inflammation and immunopathology, interferonopathies (AGS, lupus). Speaker 4 of 5 Roland W. Kolbeck, MedImmune, LLC, USA New Approaches to the Treatment of Interferon-Driven Autoimmunity
Thursday, January 23 \| 5:00PM - 7:00PM Antiviral Innate Immunity in Disease This session is from Innate Immunity Room: Longs/Grays Peaks Inflammation and immunopathology, interferonopathies (AGS, lupus). Speaker 5 of 5 Romain Bouziat, Genentech, Inc., USA Short Talk: Role of Reoviral Infections and Type 1 Interferon in Celiac Disease
Thursday, January 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Crestone/Red Cloud/Shavano
Thursday, January 23 \| 8:00PM - 11:00PM Entertainment Room: Crestone/Red Cloud/Shavano
Thursday, January 23 \| 8:00PM - 11:00PM Cash Bar Room: Crestone/Red Cloud/Shavano
Friday, January 24 \| 10:25AM - 10:25AM Departure *Session Chair.