Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
HIV Vaccines (2019X7)
Progress and Pathways Toward an Effective HIV Vaccine (2018J6)
HIV Vaccines (2017C9)
HIV Vaccines (2016X8)
HIV Vaccines (2015X5)

Web Desc
HIV Vaccines: Adaptive Immunity and Beyond joint with HIV Pathogenesis - Virus vs. Host Organizer(s): Nicole Frahm, Susan W. Barnett and Galit Alter Date: March 09 - 14, 2014 Location: Fairmont Banff Springs, Banff, AB, Canada Sponsored by Sangamo BioSciences, Inc. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation Summary of Meeting: The HIV vaccine field has undergone dramatic changes over the last several years: from the failure of the promising MRKAd5-HIV-1 vaccine to provide any protection from acquisition or disease progression to the first demonstration that an HIV vaccine can actually show efficacy with a regimen that was predicted to fail in RV144. Following these developments, the field has turned from T-cell based vaccines favored for the late nineties/early 2000s back to antibody-inducing strategies, although with a reduced focus on broadly neutralizing antibodies since these were not detected in RV144 vaccinees. This meeting aims at bringing the cellular and humoral factions together to work on a holistic approach to HIV vaccination: induction of antibodies – both binding and neutralizing – to prevent infection; a safety net of CD8 T-cell responses to control viral replication in those hosts that do become infected; and CD4 T cell help for both effector arms. In addition, we seek to provide a better understanding of the interplay of innate immune responses and the resulting adaptive response, as well as a closer look at the signals that are crucial for the induction of long-lasting memory responses. This comprehensive approach to vaccinology will be complemented by a thorough portrayal of HIV transmission, both from the viral perspective as well as the portal of entry; and by a closer look of how vaccines interact with the host’s genetic profile. Taken together, this meeting will bring scientists from all denominations together to tackle the design of a new generation of highly effective HIV vaccines. Global Health Travel Award Deadline: October 8 2013 Scholarship Deadline: November 7 2013 Discounted Abstract Deadline: November 7 2013 Abstract Deadline: December 11 2013 Discounted Registration Deadline: January 10 2014 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Novartis Vaccines and Diagnostics We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI110241-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

HIV Vaccines: Adaptive Immunity and Beyond

joint with HIV Pathogenesis - Virus vs. Host

Organizer(s): Nicole Frahm, Susan W. Barnett and Galit Alter

Date: March 09 - 14, 2014
Location: Fairmont Banff Springs, Banff, AB, Canada

Sponsored by Sangamo BioSciences, Inc. Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

Summary of Meeting:

The HIV vaccine field has undergone dramatic changes over the last several years: from the failure of the promising MRKAd5-HIV-1 vaccine to provide any protection from acquisition or disease progression to the first demonstration that an HIV vaccine can actually show efficacy with a regimen that was predicted to fail in RV144. Following these developments, the field has turned from T-cell based vaccines favored for the late nineties/early 2000s back to antibody-inducing strategies, although with a reduced focus on broadly neutralizing antibodies since these were not detected in RV144 vaccinees. This meeting aims at bringing the cellular and humoral factions together to work on a holistic approach to HIV vaccination: induction of antibodies – both binding and neutralizing – to prevent infection; a safety net of CD8 T-cell responses to control viral replication in those hosts that do become infected; and CD4 T cell help for both effector arms. In addition, we seek to provide a better understanding of the interplay of innate immune responses and the resulting adaptive response, as well as a closer look at the signals that are crucial for the induction of long-lasting memory responses. This comprehensive approach to vaccinology will be complemented by a thorough portrayal of HIV transmission, both from the viral perspective as well as the portal of entry; and by a closer look of how vaccines interact with the host’s genetic profile. Taken together, this meeting will bring scientists from all denominations together to tackle the design of a new generation of highly effective HIV vaccines.

Global Health Travel Award Deadline: October 8 2013

Scholarship Deadline: November 7 2013

Discounted Abstract Deadline: November 7 2013

Abstract Deadline: December 11 2013

Discounted Registration Deadline: January 10 2014

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Novartis Vaccines and Diagnostics

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI110241-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 09 \| 4:00PM - 8:00PM Arrival and Registration Room: Van Horne Foyer
Sunday, March 09 \| 4:30PM - 6:00PM Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endg ame Room: Shaughnessy Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.
Monday, March 10 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Monday, March 10 \| 8:00AM - 9:00AM Opening Addresses (Joint) Room: Van Horne Ballroom A/B Speaker 1 of 4 * Nicole Frahm, Bill & Melinda Gates Medical Research Institute, USA
Monday, March 10 \| 8:00AM - 9:00AM Opening Addresses (Joint) Room: Van Horne Ballroom A/B Speaker 2 of 4 * J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill, USA
Monday, March 10 \| 8:00AM - 9:00AM Opening Addresses (Joint) Room: Van Horne Ballroom A/B Speaker 3 of 4 Myron S. Cohen, University of North Carolina at Chapel Hill, USA Integrated HIV Prevention Strategies: High Time for a Synergistic Approach
Monday, March 10 \| 8:00AM - 9:00AM Opening Addresses (Joint) Room: Van Horne Ballroom A/B Speaker 4 of 4 Carl W. Dieffenbach, NIAID, National Institutes of Health, USA The Big Questions: The Basic Research Progress Needed to Help Control the HIV/AIDS Pandemic
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 1 of 7 * James A. Hoxie, University of Pennsylvania, USA
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 2 of 7 * Thomas Musich, Armed Forces Research Institute of Medical Sciences, Thailand
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 3 of 7 J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill, USA Mechanistic Analysis of Vaginal HIV Transmission and Prevention
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 4 of 7 Peter A. Anton, David Geffen School of Medicine at UCLA, USA Rectal HIV Transmission
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 5 of 7 Ashley T. Haase, University of Minnesota, USA Virus-Host Immune Interactions at the Portal of Entry and Vaccine Design to Prevent HIV-1 Transmission to Women
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 6 of 7 Thomas J. Hope, Northwestern University, USA Short Talk: Hotspots of SIV Infection in the Female Reproductive Tract after Vaginal Exposure of Rhesus macaques to Single Round Dual Reporter Vector
Monday, March 10 \| 9:00AM - 11:30AM Portals of Entry and Sites of Dissemination (Joint) Room: Van Horne Ballroom A/B Speaker 7 of 7 Samuel K. Lai, University of North Carolina at Chapel Hill, USA Short Talk: Influence of Vaginal Microbiota on the Diffusional Barrier Properties of Cervicovaginal Mucus against HIV
Monday, March 10 \| 9:40AM - 10:00AM Coffee Break Room: Van Horne Foyer
Monday, March 10 \| 11:30AM - 1:00PM Poster Setup Room: Mezzanine 2
Monday, March 10 \| 11:30AM - 2:30PM On Own for Lunch and Recreation
Monday, March 10 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 1 of 10 * Marjorie Robert-Guroff, NCI, National Institutes of Health, USA
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 2 of 10 * Thomas J. Hope, Northwestern University, USA
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 3 of 10 Liang Shang, University of Minnesota, USA Immune Complex – Fc Receptor Interactions Reduce Inflammatory Responses at the Genital Mucosa as a Correlate of SIV Vaccine-Induced Protection
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 4 of 10 Yichuan Wang, NCI, National institutes of Health, USA Vaginal Type-II Mucosa Acts as an Inductive Site for the Generation of Primary CD8+ T Cell Mucosal Immune Responses
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 5 of 10 Genoveffa Franchini, NCI, National Institutes of Health, USA Modulation of the RAS Pathways as a Biomarker of Protection Against HIV and as a Means to Improve Vaccine Efficacy
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 6 of 10 Rena D. Astronomo, Fred Hutchinson Cancer Research Center, USA Neutrophils May Provide Front-Line Antibody Effector Functions in the Cervical But Not the Vaginal Mucosa
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 7 of 10 Béhazine Combadiere, Centre d'Immunologie et des Maladies Infectieuses, France Cutaneous Routes for HIV Vaccination Strategies
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 8 of 10 Sampa Santra, Harvard Medical School, USA Simian-Human Immunodeficiency Viruses with Transmitted/Founder Clade C HIV-1 Envelopes
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 9 of 10 Thorsten Demberg, NCI, National Institutes of Health, USA Phenotyping and Characterization of Mucosal Memory B-Cell Populations in the SIV/SHIV Rhesus macaque Model
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Mucosal Immunity Room: Van Horne Ballroom A/B Speaker 10 of 10 Thomas Musich, Armed Forces Research Institute of Medical Sciences, Thailand Purification and Functional Characterization of Mucosal IgA from Vaccinated and SIV-Infected Rhesus macaques
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 10 * Roberto F. Speck, University of Zurich, Switzerland
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 10 * Frank Kirchhoff, University of Ulm, Germany
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 10 Atef F. Allam, Walter Reed Institute of Research, USA Characterization of B- and T Cells in the Gut Mucosa of Humanized DRAG Mice During HIV Infection
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 10 Timothy E. Dudek, Ragon Institute of MGH, MIT and Harvard, USA Immunization of Humanized BLT Mice Against HIV Influences Early Immune Responses and Viral Loads
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 10 Yanhui Cai, Tulane National Primate Research Center, USA SIV Infection of Lung Interstitial Macrophages Contributes to Tissue Damage and Inflammatory Responses in the Lung
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 10 Christopher A. Gaulke, University of California, Davis, USA SIV Induced Disruption of microRNA Expression in the Small Intestine Contributes to Epithelial Barrier Dysfunction
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 10 Jung Joo Hong, Korea Research Institute of Bioscience and Biotechnology, South Korea Early Lymphoid Responses and Germinal Center Formation Correlates with Lower Viral Load Set Points and Better Prognosis of SIV Infection
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 8 of 10 Luca Micci, Emory University, YNPRC, USA Interleukin-21 Reduces Residual Immune Activation in ART-Suppressed SIV-Infected Rhesus macaques by Restoring Intestinal Th17 and Th22 Cells
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 9 of 10 M. Christine Zink, Johns Hopkins University, USA Sustained Upregulation of Neurotoxic Kynurenine Pathway Metabolites in cART-Treated SIV-Infected Pigtailed Macaques: Impact on Neuroinflammation and Serotonin Metabolism
Monday, March 10 \| 2:30PM - 4:30PM Workshop 1: Role of Animal Models for HIV Research This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 10 of 10 Adrienne E. Swanstrom, University of Pennsylvania, USA In Vivo Evaluation of a Novel Variant of SIVmac Lacking CD4 Tropism
Monday, March 10 \| 3:30PM - 5:00PM Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endg ame Room: Shaughnessy Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.
Monday, March 10 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 1 of 7 * Rafael Cubas, Genentech, USA
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 2 of 7 * Hendrik Streeck, Military HIV Research Program, USA
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 3 of 7 Robert A. Seder, NIAID, National Institutes of Health, USA Development of a Malaria Vaccine: A Parable of Vaccine Delivery, Breadth of Antigens and Effector Cells
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 4 of 7 Mark K. Slifka, Oregon National Primate Research Center, Oregon Health & Science University, USA Potential Mechanisms for Sustaining Long-Term Humoral Immunity
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 5 of 7 Shane Crotty, La Jolla Institute for Immunology, USA Tfh Cells and Memory Tfh Cells
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 6 of 7 Diego J. Farfán-Arribas, University of Massachusetts Medical School, USA Short Talk: Evidence on the Involvement of Germinal Centers and T Follicular Helper Cells in DNA Immunization for HIV Vaccine Development
Monday, March 10 \| 5:00PM - 7:15PM Programming Durable Immunity Room: Van Horne Ballroom A/B Speaker 7 of 7 Ann J. Hessell, Oregon Health & Science University, USA Short Talk: Cross-Clade Neutralizing Antibodies and Envelope-Specific TFH Cell Responses Are Elicited in Macaques Co-Immunized with DNA and Protein Env Vaccines Derived from Multiple Subjects during Development of Breadth
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 8 * Quentin J. Sattentau, Sir William Dunn School of Pathology, UK
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 8 * Doris Wilflingseder, Insbruck Medical University, Austria
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 8 Welkin E. Johnson, Boston College, USA Genetic Barriers to Cross-Species Transmission and Emergence of Primate Immunodeficiency Viruses
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 8 Robert J. Gifford, University of Glasgow, UK The Evolution and Emergence of Lentiviral Pandemics since the Neolithic Era
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 8 Viviana Simon, Icahn School of Medicine at Mount Sinai, USA Short Talk: HIV Evolution in Humanized Mice
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 8 Li Wu, Ohio State University, USA Short Talk: Identification of Cellular Proteins Interacting with the Retroviral Restriction Factor SAMHD1
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 8 Thijs Booiman, University of Amsterdam, Netherlands Short Talk: The Effect of Genetic Variation in Trex1 on HIV-1 Disease Progression and in vitro HIV-1 Replication
Monday, March 10 \| 5:00PM - 7:15PM Host-Viral Co-Evolution This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 8 of 8 Angelique Hoelzemer, Ragon Institute of MGH, MIT and Harvard, USA Short Talk: Selection of a Distinct HIV-1 p24 Gag Sequence Polymorphism in KIR2DL3/HLA-C03:04+ Individuals Is Associated with Viral Escape from Recognition by KIR2DL3+ NK Cells*
Monday, March 10 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mezzanine 2
Monday, March 10 \| 7:30PM - 10:00PM Poster Session 1 Room: Mezzanine 2
Tuesday, March 11 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Tuesday, March 11 \| 7:30AM - 8:00AM Poster Setup Room: Mezzanine 2
Tuesday, March 11 \| 8:00AM - 7:00PM Poster Viewing Room: Mezzanine 2
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 1 of 8 * Anne-Sophie M. Dugast, Ragon Institute of MGH, MIT and Harvard, USA
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 2 of 8 * Adrian B. McDermott, National Institutes of Health, USA
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 3 of 8 William H. Robinson, Stanford University School of Medicine, USA Protective B Cell Responses
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 4 of 8 Gabriel D. Victora, Rockefeller University, USA Cellular Dynamics and Clonal Selection in the Germinal Center
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 5 of 8 Jonathan W. Yewdell, NIAID, National Institutes of Health, USA Translating Information for MHC Class Immunosurveillance
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 6 of 8 Susan W. Barnett, Bill & Melinda Gates Foundation, USA Non-Viral Delivery of Self-Amplifying mRNA: A Versatile Synthetic Vaccine Platform for HIV
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 7 of 8 Kelly D. Moynihan, Third Rock Ventures, USA Short Talk: Lymph-Node Targeting of Molecular Vaccines through “Albumin Hitchhiking”
Tuesday, March 11 \| 8:00AM - 11:00AM Inducing Protective Immunity Room: Van Horne Ballroom A/B Speaker 8 of 8 Joseph G. Jardine, The Scripps Research Institute, USA Short Talk: Design of Germline-Targeted Immunogens with Enhanced Breadth for VRC01-Class Precursors
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 8 * Eric Hunter, Emory University, USA
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 8 * Gilda Tachedjian, Burnet Institute, Australia
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 8 Wesley I. Sundquist, University of Utah School of Medicine, USA HIV Assembly and Egress
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 8 Vineet N. KewalRamani, NCI, National Institutes of Health, USA HIV Entry and Nuclear Translocation
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 8 Fadila Bouamr, NIAID, National Institutes of Health, USA The Host and HIV Exit
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 8 Janice E. Clements, Johns Hopkins University, USA Macrophages Contribute to the Latent Viral Reservoir in Tissues of cART Suppressed SIV-Infected Macaques
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 8 Peijun Zhang, University of Oxford, UK Short Talk: Structural Mechanisms of HIV-1 Capsid Assembly and Maturation
Tuesday, March 11 \| 8:00AM - 11:15AM Viral Entry/Exit and Host Genetics This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 8 of 8 Amy Hulme, Northwestern University, USA Short Talk: Viral and Cellular Factors Affect HIV-1 Uncoating
Tuesday, March 11 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Tuesday, March 11 \| 11:15AM - 12:15PM Lunch Room: Mezzanine 2
Tuesday, March 11 \| 12:00PM - 2:30PM Poster Session 2 Room: Mezzanine 2
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 1 of 7 * Carl W. Dieffenbach, NIAID, National Institutes of Health, USA
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 2 of 7 Galit Alter, MIT and Harvard University, USA
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 3 of 7 Peter A. Anton, David Geffen School of Medicine at UCLA, USA
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 4 of 7 Myron S. Cohen, University of North Carolina at Chapel Hill, USA
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 5 of 7 Magdalena E. Sobieszczyk, Columbia University, USA
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 6 of 7 David M. Margolis, University of North Carolina at Chapel Hill, USA
Tuesday, March 11 \| 2:30PM - 4:30PM Panel 1: HIV/AIDS: Strategies for an Endgame (Joint) Room: Van Horne Ballroom A/B Keystone Symposia is pleased to present a panel discussion on the topic of 'HIV/AIDS: Strategies for an Endgame' moderated by Dr. Carl Dieffenbach, Director of the Division of AIDS Research at NIAID. The panel builds on discussions from our first virtual, live webcast on the same topic, originally broadcast in December of 2013, and offers opportunities for audience participation. The original webcast is being shown several times during the current meeting in the Shaughnessy Room and can also be viewed online at any time at www.visualwebcaster.com/KSHIV. Speaker 7 of 7 Thomas C. Quinn, NIAID and Johns Hopkins University, USA
Tuesday, March 11 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 1 of 7 * Richard A. Koup, NIAID, National Institutes of Health, USA
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 2 of 7 * Edward A. Berger, NIAID, National Institutes of Health, USA
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 3 of 7 Beatrice H. Hahn, University of Pennsylvania, USA Phenotypic Properties of Transmitted Founder HIV-1
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 4 of 7 Bette Tina Marie Korber, Los Alamos National Laboratory, USA Using Signatures of Neutralizing Antibodies to Inform Vaccine Design
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 5 of 7 Andrew B. Ward, The Scripps Research Institute, USA High-Resolution Cryo-EM Studies of HIV-1 Env
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 6 of 7 Dan H. Barouch, Beth Israel Deaconess Medical Center, USA Short Talk: Prospects for Monoclonal Antibody Therapy for HIV-1
Tuesday, March 11 \| 5:00PM - 7:15PM Tackling Global HIV Diversity Room: Van Horne Ballroom A/B Speaker 7 of 7 Devin Sok, International AIDS Vaccine Initiative, USA Short Talk: Promiscuous Glycan Site Recognition by Antibodies to the High-Mannose Patch of gp120 Facilitates Broader Neutralization of HIV
Tuesday, March 11 \| 5:00PM - 7:00PM Mechanistic Models of Pathogenesis and Disease This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 6 * Heinrich Gottlinger, University of Massachusetts Medical School, USA
Tuesday, March 11 \| 5:00PM - 7:00PM Mechanistic Models of Pathogenesis and Disease This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 6 * Shokrollah Elahi, University of Alberta, Canada
Tuesday, March 11 \| 5:00PM - 7:00PM Mechanistic Models of Pathogenesis and Disease This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 6 Richard T. D'Aquila, Northwestern University, USA APOBEC3s versus Vif-Positive HIV-1: Tipping the Balance toward Virus Control
Tuesday, March 11 \| 5:00PM - 7:00PM Mechanistic Models of Pathogenesis and Disease This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 6 Timothy W. Schacker, University of Minnesota, USA The Natural History of HIV Infection in Lymphatic Tissues
Tuesday, March 11 \| 5:00PM - 7:00PM Mechanistic Models of Pathogenesis and Disease This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 6 Anthony L. Cunningham, Westmead Institute for Medical Research, Australia Short Talk: HIV Inhibits Interferon Production in Macrophages and Dendritic Cells but Exerts Other Antiviral Mechanisms
Tuesday, March 11 \| 5:00PM - 7:00PM Mechanistic Models of Pathogenesis and Disease This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 6 Anna Aldovini, Boston Children's Hospital and Harvard Medical School, USA Short Talk: HIV-1 Tat Engagement of Different Promoters in Different Cell Types Results in Apoptosis of CD4+ T Cells and Activation of ISG Linked to Immune Activation in Antigen Presenting Cells
Tuesday, March 11 \| 7:15PM - 7:15PM On Own for Dinner
Wednesday, March 12 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 1 of 8 * Genoveffa Franchini, NCI, National Institutes of Health, USA
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 2 of 8 * Jeffrey Robert Schneider, Northwestern University, USA
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 3 of 8 Silke Paust, Baylor College of Medicine, USA NK Memory to Experimental HIV Vaccines in Mice and Humanized Mice
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 4 of 8 Galit Alter, MIT and Harvard University, USA Fc-Signatures of Functional HIV-Specific Antibodies
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 5 of 8 Penny L. Moore, University of the Witwatersrand and National Institute for Communicable Diseases, South Africa Evolution of V1V2 Broad Neutralizing Antibodies during HIV-1 Infection
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 6 of 8 Louis J. Picker, Oregon Health & Science University, USA Effector Memory T-Cell Targeted Vaccines
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 7 of 8 Susan Johnson, US Military HIV Research Program, USA Short Talk: HIV-Specific Cytolytic CD4 T Cells Are Distinct from Th1 Cells and Preserved in HIV Infection
Wednesday, March 12 \| 8:00AM - 11:15AM Novel Mechanisms for Vaccine-Induced Protection Room: Van Horne Ballroom A/B Speaker 8 of 8 Anna Aldovini, Boston Children's Hospital and Harvard Medical School, USA Short Talk: Resistance to Infection, Early and Persistent Suppression of SIVmac251 Viremia and Significant Reduction of Tissue Viral Burden after Mucosal Vaccination in Females Rhesus macaques
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 8 * Paul R. Clapham, University of Massachusetts Medical School, USA
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 8 * Jaisri R. Lingappa, University of Washington, USA
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 8 Michael Emerman, Fred Hutchinson Cancer Research Center, USA How Ancient Host-Virus Interactions Shaped the Modern HIV-1 Pandemic in Humans
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 8 Theodora Hatziioannou, Aaron Diamond AIDS Research Center (ADARC), USA Restriction Factors and the Adaptation of HIV-1 to Non-Human Primates
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 8 Andrea Cimarelli, CIRI, International Center for Infectology Research, France Exploring the Multiple Layers of Complexity Existing during the Early Phases of Infection of Myeloid Cells by Primate Lentiviruses
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 8 Reuben S. Harris, University of Minnesota, USA Natural Resistance to HIV Infection by Select APOBEC3H Haplotypes
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 8 Daniel Claiborne, Ragon Institute of MGH, MIT, and Harvard, USA Short Talk: Protective HLA Alleles Reduce Markers of Gut Damage and Microbial Translocation and Influence Early Inflammatory Cytokine Profiles
Wednesday, March 12 \| 8:00AM - 11:15AM Host-Virus Interactions and Responses This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 8 of 8 Rui Andre Raposo, George Washington University, USA Short Talk: Increased Expression of Host Restriction Factors in HLA-B57+ Individuals*
Wednesday, March 12 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Wednesday, March 12 \| 11:15AM - 12:45PM Hands-On Computer Session on Los Alamos HIV Sequence Databas e Room: Beatty Maximum attendance: 60 Interested participants may sign up at the meeting on a first-come, first-serve basis. Speaker 1 of 3 * Brian T. Foley, Los Alamos National Lab, USA
Wednesday, March 12 \| 11:15AM - 12:45PM Hands-On Computer Session on Los Alamos HIV Sequence Databas e Room: Beatty Maximum attendance: 60 Interested participants may sign up at the meeting on a first-come, first-serve basis. Speaker 2 of 3 * Bette Tina Marie Korber, Los Alamos National Laboratory, USA
Wednesday, March 12 \| 11:15AM - 12:45PM Hands-On Computer Session on Los Alamos HIV Sequence Databas e Room: Beatty Maximum attendance: 60 Interested participants may sign up at the meeting on a first-come, first-serve basis. Speaker 3 of 3 * Will Fischer, Los Alamos National Laboratory, USA
Wednesday, March 12 \| 11:15AM - 1:00PM Poster Setup Room: Mezzanine 2
Wednesday, March 12 \| 12:45PM - 2:30PM On Own for Lunch and Recreation
Wednesday, March 12 \| 1:00PM - 10:00PM Poster Viewing Room: Mezzanine 2
Wednesday, March 12 \| 2:30PM - 4:30PM Panel 2: Functions of Protective Antibodies Room: Van Horne Ballroom A/B Speaker 1 of 6 Stephen J. Kent, University of Melbourne, Australia
Wednesday, March 12 \| 2:30PM - 4:30PM Panel 2: Functions of Protective Antibodies Room: Van Horne Ballroom A/B Speaker 2 of 6 Margaret E. Ackerman, Dartmouth College, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Panel 2: Functions of Protective Antibodies Room: Van Horne Ballroom A/B Speaker 3 of 6 Nancy L. Haigwood, Oregon Health & Science University, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Panel 2: Functions of Protective Antibodies Room: Van Horne Ballroom A/B Speaker 4 of 6 Ruth M. Ruprecht, Texas Biomedical Research Institute, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Panel 2: Functions of Protective Antibodies Room: Van Horne Ballroom A/B Speaker 5 of 6 James Arthos, NIAID, National Institutes of Health, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Panel 2: Functions of Protective Antibodies Room: Van Horne Ballroom A/B Speaker 6 of 6 * Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 10 * Brenda L. Fredericksen, NIAID, National Institutes of Health, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 10 * Pamela J. Skinner, University of Minnesota, USA
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 10 Joe Casazza, NIAID, National Institutes of Health, USA Identification of HIV-Infected CD4+ T Cells using HIV RNA and Broadly Neutralizing Antibodies
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 10 Andrew N. Harman, Westmead Institute, Australia The Role of Mucosal Dendritic Cells in HIV Infection
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 10 Rosa Camacho, Instituto Nacional de Enfermedades Respiratorias, Mexico TNFalpha Overproduction by Conventional Dendritic Cells in Viremic versus Controller HIV Subjects
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 10 Alexandre Deshiere, Laval University, Canada Transcriptomic and Proteomic Screening of Host Genes Modulated by HIV-1 in Human Macrophages: A Highly Sensitive Strategy for the Identification of New Susceptibility/Restriction Factors
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 10 Katharina Borm, Burnet Institute, Australia Envelope Glycoprotein Determinants of Macrophages Tropism during Progressive HIV-1 Subtype C Infection
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 8 of 10 Maria Paz Gonzalez-Perez, UMASS, USA HIV-1 R5 Envelopes from Brain and Immune Tissue of AIDS Patients with Normal Neurology are Less Functional and Less Macrophage-Tropic Compared to those in HAD Patients
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 9 of 10 Sheila M. Keating, GigaGen, USA Cerebrospinal Fluid and Blood Inflammatory Biomarkers are Differentially Elevated in HIV and Neurological Disease
Wednesday, March 12 \| 2:30PM - 4:30PM Workshop 2: It Is All in the Head: HIV, Macs, DCs and the CN S This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 10 of 10 David R. Graham, Johns Hopkins School of Medicine, USA A Combined Proteomics and Metabolomics Study of CSF from HAND Patients Under cART Therapy Reveals Evidence for Ongoing Macrophage Activation and Pertubations in Glutamate Metabolism
Wednesday, March 12 \| 3:30PM - 5:00PM Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endg ame Room: Shaughnessy Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.
Wednesday, March 12 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Wednesday, March 12 \| 5:00PM - 7:15PM Engineering Protective Immune Responses Room: Van Horne Ballroom A/B Speaker 1 of 6 * Rena D. Astronomo, Fred Hutchinson Cancer Research Center, USA
Wednesday, March 12 \| 5:00PM - 7:15PM Engineering Protective Immune Responses Room: Van Horne Ballroom A/B Speaker 2 of 6 * Mark Connors, NIAID, National Institutes of Health, USA
Wednesday, March 12 \| 5:00PM - 7:15PM Engineering Protective Immune Responses Room: Van Horne Ballroom A/B Speaker 3 of 6 William Schief, International AIDS Vaccine Initiative and The Scripps Research Institute, USA Vaccines to Induce Broadly Neutralizing Antibodies
Wednesday, March 12 \| 5:00PM - 7:15PM Engineering Protective Immune Responses Room: Van Horne Ballroom A/B Speaker 4 of 6 Nicholas M. Valiante, Novartis Vaccines and Diagnostics, USA Minimal Essential Adjuvants: A Rational Approach for Optimizing Small Molecules as Vaccine Adjuvants
Wednesday, March 12 \| 5:00PM - 7:15PM Engineering Protective Immune Responses Room: Van Horne Ballroom A/B Speaker 5 of 6 Mario Roederer, NIAID, National Institutes of Health, USA Antigenic Heterogeneity of Clonal Envelopes: A Novel Immune Evasion Mechanism
Wednesday, March 12 \| 5:00PM - 7:15PM Engineering Protective Immune Responses Room: Van Horne Ballroom A/B Speaker 6 of 6 Louise Scharf, California Institute of Technology, USA Short Talk: A New Site of Broad Vulnerability on the HIV-1 Envelope Spike Defined by a Patient-Derived Antibody
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 7 * Charles R. Rinaldo, University of Pittsburgh, USA
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 7 * John C. Tilton, Case Western Reserve University, USA
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 7 Dan R. Littman, HHMI/New York University School of Medicine, USA Immue Homeostasis and Commensal Bacteria
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 7 Nichole R. Klatt, University of Miami, USA Kinetics of Mucosal Dysfunction after SIV Infection of Rhesus macaques
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 7 Satya Dandekar, University of California, Davis, USA HIV Pathogenesis: The GALT
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 7 Brent E. Palmer, University of Colorado Health Sciences Center, USA Short Talk: Alterations in the Gut Microbiota Associated with HIV Infection
Wednesday, March 12 \| 5:00PM - 7:15PM HIV, the Microbiome and the Mucosa This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 7 Hannah J. Barbian, University of Pennsylvania, USA Short Talk: Evaluating the Enteric Virome as a Marker of Disease Progression in SIVcpz Infected Wild-Living Chimpanzees
Wednesday, March 12 \| 7:15PM - 8:15PM Social Hour with Lite Bites Room: Mezzanine 2
Wednesday, March 12 \| 7:30PM - 10:00PM Poster Session 3 Room: Mezzanine 2
Thursday, March 13 \| 7:00AM - 8:00AM Breakfast Room: Mezzanine 2
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 1 of 8 * Liang Shang, University of Minnesota, USA
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 2 of 8 * William A. Paxton, Institute of Infection and Global Health, UK
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 3 of 8 Nicole Frahm, Bill & Melinda Gates Medical Research Institute, USA Immunogenicity of HIV Vaccine Candidates in the HIV Vaccine Trials Network (HVTN)
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 4 of 8 Magdalena E. Sobieszczyk, Columbia University, USA Lessons from HVTN 505 Efficacy Trial of a DNA/rAd5 HIV Preventive Vaccine
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 5 of 8 Jerome H. Kim, International Vaccine Institute, South Korea RV144 and HIV Acquisition: Insights and New Questions
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 6 of 8 Thomas C. Quinn, NIAID and Johns Hopkins University, USA The Impact of Combination Prevention on the HIV Pandemic
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 7 of 8 Susan Zolla-Pazner, Icahn School of Medicine at Mount Sinai, USA Short Talk: IgG V3-Specific Antibody (Ab) Reactivity in Plasma from RV144: Implications for Vaccine Efficacy
Thursday, March 13 \| 8:00AM - 11:15AM From Concepts to Implementation Room: Van Horne Ballroom A/B Speaker 8 of 8 Iskra Tuero, Universidad Peruana Cayetano Heredia, Peru Short Talk: SIV Trimeric versus Monomeric Env-Induced Antibodies and Delayed SIV Acquisition in Vaccinated Female Rhesus macaques
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 1 of 8 * Robert W. Buckheit, Jr., ImQuest BioSciences, Inc., USA
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 2 of 8 * Linda Chelico, University of Saskatchewan, Canada
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 3 of 8 Daria J. Hazuda, Merck Research Laboratories, USA New Drug Targets in the Search for an HIV Cure
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 4 of 8 David M. Margolis, University of North Carolina at Chapel Hill, USA HIV Eradication Approaches
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 5 of 8 Hiroyu Hatano, University of California, San Francisco, USA HIV Persistence in 'Elite' Controllers
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 6 of 8 Steven Wolinsky, Northwestern University, USA Persistent HIV-1 Replication and Evolution in Drug Sanctuaries within Peripheral Lymphoid Organ Compartments in Patients on Combination Antiretroviral Therapy
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 7 of 8 Edward A. Berger, NIAID, National Institutes of Health, USA Short Talk: Novel CD4-Based Chimeric Antigen Receptors: Toward an HIV Functional Cure Using Genetically Modified CD8+ T Cells
Thursday, March 13 \| 8:00AM - 11:15AM Reservoirs, Latency, Reactivation and Eradication This session is from HIV Pathogenesis Room: Van Horne Ballroom C Speaker 8 of 8 Scott G. Kitchen, University of California, Los Angeles AIDS Institute, USA Short Talk: Engineering Stem Cells with Chimeric Antigen Receptors for HIV-Specific T Cell Immunity
Thursday, March 13 \| 9:20AM - 9:40AM Coffee Break Room: Van Horne Foyer
Thursday, March 13 \| 11:15AM - 12:45PM Hands-On Computer Session on Los Alamos HIV Immunology Datab ase Room: Beatty Maximum attendance: 60 Interested participants may sign up at the meeting on a first-come, first-serve basis. Speaker 1 of 3 * Brian T. Foley, Los Alamos National Lab, USA
Thursday, March 13 \| 11:15AM - 12:45PM Hands-On Computer Session on Los Alamos HIV Immunology Datab ase Room: Beatty Maximum attendance: 60 Interested participants may sign up at the meeting on a first-come, first-serve basis. Speaker 2 of 3 * Bette Tina Marie Korber, Los Alamos National Laboratory, USA
Thursday, March 13 \| 11:15AM - 12:45PM Hands-On Computer Session on Los Alamos HIV Immunology Datab ase Room: Beatty Maximum attendance: 60 Interested participants may sign up at the meeting on a first-come, first-serve basis. Speaker 3 of 3 * Will Fischer, Los Alamos National Laboratory, USA
Thursday, March 13 \| 12:45PM - 2:30PM On Own for Lunch and Recreation
Thursday, March 13 \| 2:30PM - 4:30PM Panel 3: Triggering Protective B-Cell Responses Room: Van Horne Ballroom A/B Speaker 1 of 6 * George K. Lewis, University of Maryland, USA
Thursday, March 13 \| 2:30PM - 4:30PM Panel 3: Triggering Protective B-Cell Responses Room: Van Horne Ballroom A/B Speaker 2 of 6 M. Anthony Moody, Duke University Medical Center, USA
Thursday, March 13 \| 2:30PM - 4:30PM Panel 3: Triggering Protective B-Cell Responses Room: Van Horne Ballroom A/B Speaker 3 of 6 Rogier W. Sanders, University of Amsterdam and Weill Cornell Medical College, Netherlands Neutralizing Antibodies Induced by a Soluble Cleaved HIV Envelope Trimer, BG505 SOSIP.664 gp140
Thursday, March 13 \| 2:30PM - 4:30PM Panel 3: Triggering Protective B-Cell Responses Room: Van Horne Ballroom A/B Speaker 4 of 6 Jens P. Wrammert, Emory University, USA Interrogating SIV/HIV Specific Plasmablast Responses in Rhesus macaques
Thursday, March 13 \| 2:30PM - 4:30PM Panel 3: Triggering Protective B-Cell Responses Room: Van Horne Ballroom A/B Speaker 5 of 6 Alejandro Balazs, Massachusetts General Hospital, USA
Thursday, March 13 \| 2:30PM - 4:30PM Panel 3: Triggering Protective B-Cell Responses Room: Van Horne Ballroom A/B Speaker 6 of 6 Burton E. Barnett, Genomics Institute of the Novartis Research Foundation, USA
Thursday, March 13 \| 3:30PM - 5:00PM Keystone Symposia Webcast - HIV/AIDS: Strategies for an Endg ame Room: Shaughnessy Taped rebroadcast of the first virtual Keystone Symposia event. This can also be viewed online at any time at www.visualwebcaster.com/KSHIV.
Thursday, March 13 \| 4:30PM - 5:00PM Coffee Available Room: Van Horne Foyer
Thursday, March 13 \| 5:00PM - 6:45PM Cellular and Genetic Therapies for HIV/AIDS (Joint) Room: Van Horne Ballroom A/B Speaker 1 of 5 * Nicole Frahm, Bill & Melinda Gates Medical Research Institute, USA
Thursday, March 13 \| 5:00PM - 6:45PM Cellular and Genetic Therapies for HIV/AIDS (Joint) Room: Van Horne Ballroom A/B Speaker 2 of 5 * J. Victor Garcia-Martinez, University of North Carolina at Chapel Hill, USA
Thursday, March 13 \| 5:00PM - 6:45PM Cellular and Genetic Therapies for HIV/AIDS (Joint) Room: Van Horne Ballroom A/B Speaker 3 of 5 Robert F. Siliciano, Johns Hopkins University School of Medicine, USA Prospects for HIV Eradication
Thursday, March 13 \| 5:00PM - 6:45PM Cellular and Genetic Therapies for HIV/AIDS (Joint) Room: Van Horne Ballroom A/B Speaker 4 of 5 Nicolas Chomont, Université de Montréal, Canada HIV Persistence during ART: What Can We Learn from CD4 T Cell Homeostasis?
Thursday, March 13 \| 5:00PM - 6:45PM Cellular and Genetic Therapies for HIV/AIDS (Joint) Room: Van Horne Ballroom A/B Speaker 5 of 5 Jerome A. Zack, University of California, Los Angeles, USA Novel Means for Eliminating Latent HIV Reservoirs
Thursday, March 13 \| 6:45PM - 7:30PM Keynote Address (Joint) Room: Van Horne Ballroom A/B Speaker 1 of 1 Mark M. Davis, Stanford University School of Medicine, USA
Thursday, March 13 \| 7:30PM - 8:30PM Social Hour with Lite Bites Room: Mezzanine 2
Thursday, March 13 \| 8:00PM - 11:00PM Entertainment Room: Mezzanine 2
Thursday, March 13 \| 8:00PM - 11:00PM Cash Bar Room: Mezzanine 2
Friday, March 14 \| 10:25AM - 10:25AM Departure *Session Chair.