Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Cancer Metastasis: The Role of Metabolism, Immunity and the Microenvironment (2019M2)
Angiogenesis and Vascular Disease (2017Z3)

Web Desc
Metabolism and Angiogenesis joint with Tumor Metabolism Organizer(s): Peter F. Carmeliet and Michael Simons Date: March 16 - 21, 2014 Location: Whistler Conference Centre, Whistler, BC, Canada Supported by the Directors' Fund Summary of Meeting: Endothelial cells are required to be quiescent in healthy conditions while having the capacity to actively proliferate and migrate during angiogenic sprouting. The transition from quiescence to rapid proliferation requires metabolic reprogramming that is very similar to that seen in rapidly growing tumor cells. Therefore, the integration of the fields of angiogenesis, metabolism and cancer biology has become a very hot topic in biomedical research. Since blood vessels arose in evolution to deliver nutrients and oxygen, it is not surprising that angiogenesis and metabolism are closely linked. The interface of these fields also offers unprecedented opportunities for pro- and anti-angiogenic therapies. This Keystone Symposia meeting on Metabolism and Angiogenesis will enhance cross-talk between researchers in the fields of angiogenesis (vascular biology) and cellular metabolism with a view of understanding the underlying biology and for identifying opportunities for new therapeutic strategies. Opportunities for cross-fertilization of ideas and interdisciplinary interactions will be further strengthened by joint keynote and plenary sessions with the concurrent meeting on “Tumor Metabolism.” Scholarship Deadline: November 18 2013 Discounted Abstract Deadline: November 18 2013 Abstract Deadline: December 17 2013 Discounted Registration Deadline: January 15 2014 We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Regeneron Pharmaceuticals, Inc. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Cancer Institute (NCI) Grant No. 1R13CA183117-01 The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Metabolism and Angiogenesis

joint with Tumor Metabolism

Organizer(s): Peter F. Carmeliet and Michael Simons

Date: March 16 - 21, 2014
Location: Whistler Conference Centre, Whistler, BC, Canada

Supported by the Directors' Fund

Summary of Meeting:

Endothelial cells are required to be quiescent in healthy conditions while having the capacity to actively proliferate and migrate during angiogenic sprouting. The transition from quiescence to rapid proliferation requires metabolic reprogramming that is very similar to that seen in rapidly growing tumor cells. Therefore, the integration of the fields of angiogenesis, metabolism and cancer biology has become a very hot topic in biomedical research. Since blood vessels arose in evolution to deliver nutrients and oxygen, it is not surprising that angiogenesis and metabolism are closely linked. The interface of these fields also offers unprecedented opportunities for pro- and anti-angiogenic therapies. This Keystone Symposia meeting on Metabolism and Angiogenesis will enhance cross-talk between researchers in the fields of angiogenesis (vascular biology) and cellular metabolism with a view of understanding the underlying biology and for identifying opportunities for new therapeutic strategies. Opportunities for cross-fertilization of ideas and interdisciplinary interactions will be further strengthened by joint keynote and plenary sessions with the concurrent meeting on “Tumor Metabolism.”

Scholarship Deadline: November 18 2013

Discounted Abstract Deadline: November 18 2013

Abstract Deadline: December 17 2013

Discounted Registration Deadline: January 15 2014

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Regeneron Pharmaceuticals, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Cancer Institute (NCI)
Grant No. 1R13CA183117-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Sunday, March 16 \| 4:00PM - 8:00PM Arrival and Registration Room: Sea to Sky Foyer
Monday, March 17 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A
Monday, March 17 \| 8:00AM - 9:30AM Keynote Session (Joint) Room: Sea to Sky B/C Speaker 1 of 2 M. Celeste Simon, University of Pennsylvania, USA Oxygen, Lipids and Cancer Cell Metabolism
Monday, March 17 \| 8:00AM - 9:30AM Keynote Session (Joint) Room: Sea to Sky B/C Speaker 2 of 2 Steven L. McKnight, University of Texas Southwestern Medical Center, USA Acetate Consumption as a Potential Vulnerability of Certain Types of Human Tumors
Monday, March 17 \| 9:30AM - 9:50AM Coffee Break Room: Foyer
Monday, March 17 \| 9:50AM - 12:30PM Novel Metabolic Pathways in Cancer I (Joint) Room: Sea to Sky B/C Speaker 1 of 5 Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA Metabolic Pathways Important for Tumor Growth and Survival
Monday, March 17 \| 9:50AM - 12:30PM Novel Metabolic Pathways in Cancer I (Joint) Room: Sea to Sky B/C Speaker 2 of 5 David M. Sabatini, Whitehead Institute for Biomedical Research, USA Amino Acids, Sugars and Cancer Metabolism
Monday, March 17 \| 9:50AM - 12:30PM Novel Metabolic Pathways in Cancer I (Joint) Room: Sea to Sky B/C Speaker 3 of 5 Karen H. Vousden, Francis Crick Institute, UK p53-Pathway Mediated Metabolic Regulation
Monday, March 17 \| 9:50AM - 12:30PM Novel Metabolic Pathways in Cancer I (Joint) Room: Sea to Sky B/C Speaker 4 of 5 Ralph J. DeBerardinis, University of Texas Southwestern Medical Center, USA Metabolic Versatility in Cancer Cells
Monday, March 17 \| 9:50AM - 12:30PM Novel Metabolic Pathways in Cancer I (Joint) Room: Sea to Sky B/C Speaker 5 of 5 Douglas R. Green, St. Jude Children's Research Hospital, USA Balancing Act: Caspases and RIP Kinases in Cell Death and Development
Monday, March 17 \| 12:30PM - 1:00PM Poster Setup Room: Sea to Sky A
Monday, March 17 \| 12:30PM - 5:00PM On Own for Lunch and Recreation
Monday, March 17 \| 1:00PM - 10:00PM Poster Viewing Room: Sea to Sky A
Monday, March 17 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Monday, March 17 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Bidirectional Cross-Talk Room: Sea to Sky B Speaker 1 of 5 * Adrian L. Harris, University of Oxford, Weatherall Institute of Molecular Medicine, UK
Monday, March 17 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Bidirectional Cross-Talk Room: Sea to Sky B Speaker 2 of 5 Zoltan P. Arany, University of Pennsylvania, USA Endothelial PGC-1alpha Mediates Vascular Dysfunction in Diabetes
Monday, March 17 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Bidirectional Cross-Talk Room: Sea to Sky B Speaker 3 of 5 Massimo Santoro, Vesalius Research Center, Belgium Novel Non-Mitochondrial Redox Regulator in Endothelial Cells
Monday, March 17 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Bidirectional Cross-Talk Room: Sea to Sky B Speaker 4 of 5 Luisa Iruela-Arispe, University of California, Los Angeles, USA Endothelial VEGFR2 Signaling in Diabetes
Monday, March 17 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Bidirectional Cross-Talk Room: Sea to Sky B Speaker 5 of 5 Markus Jabs, German Cancer Research Center, Germany Short Talk: Notch Signaling Regulates Systemic Energy Metabolism
Monday, March 17 \| 5:00PM - 7:00PM Succinate Dehydrogenase and Fumarate Hydratase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 5 * Matthew G. Vander Heiden, Massachusetts Institute of Technology, USA
Monday, March 17 \| 5:00PM - 7:00PM Succinate Dehydrogenase and Fumarate Hydratase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 5 Patrick J. Pollard, University of Edinburgh, UK Oncometabolites: Linking Altered Metabolism With Cancer?
Monday, March 17 \| 5:00PM - 7:00PM Succinate Dehydrogenase and Fumarate Hydratase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 5 Eyal Gottlieb, Technion - Israel Institute of Technology, Israel Revealing New Metabolic Networks in FH-Deficient Tumors
Monday, March 17 \| 5:00PM - 7:00PM Succinate Dehydrogenase and Fumarate Hydratase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 4 of 5 Navdeep S. Chandel, Northwestern University, USA Targeting Mitochondrial Metabolism for Cancer Therapy
Monday, March 17 \| 5:00PM - 7:00PM Succinate Dehydrogenase and Fumarate Hydratase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 5 of 5 Paul-Joseph Penaflor Aspuria, Atara Biotherapeutics, Inc., USA Short Talk: Succinate Dehydrogenase Inhibition Leads to Epithelial-Mesenchymal Transition and Reprogrammed Carbon Metabolism
Monday, March 17 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Monday, March 17 \| 7:30PM - 10:00PM Poster Session 1 Room: Sea to Sky A
Tuesday, March 18 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 1 of 8 * Luisa Iruela-Arispe, University of California, Los Angeles, USA
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 2 of 8 Michael Potente, Max Planck Institute for Heart and Lung Research, Germany Linking Angiogenesis and Metabolism through FOXO Transcription Factors
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 3 of 8 Peter F. Carmeliet, University of Leuven, VIB, Belgium Targeting Endothelial Metabolism: Principles and Strategies
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 4 of 8 Annika Keller, Zurich University Hospital, Switzerland Endothelial-Pericyte Signaling and Brain Disease
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 5 of 8 Hilary A. Coller, University of California, Los Angeles, USA Tumor Stromal Cells
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 6 of 8 Kari K. Alitalo, University of Helsinki, Finland VEGF-B in Metabolic Reprogramming and Cardiovascular Disease
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 7 of 8 Peter D. Westenskow, The Scripps Research Institute, USA Short Talk: Cone Photoreceptors Generate the Fatty Acid Amide Erucamide for Maintenance of the Ocular Vasculature
Tuesday, March 18 \| 8:00AM - 11:15AM Metabolism and Vascular Branching Room: Sea to Sky B Speaker 8 of 8 Pengchun Yu, Yale School of Medicine, USA Short Talk: Regulation of Lymphangiogenesis by FGF Signaling
Tuesday, March 18 \| 8:00AM - 11:15AM Isocitrate Dehydrogenase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 6 William G. Kaelin, Jr., Dana-Farber Cancer Institute, USA The von Hippel-Lindau Tumor Suppressor Protein: Insights into Oxygen Sensing and Cancer Metabolism
Tuesday, March 18 \| 8:00AM - 11:15AM Isocitrate Dehydrogenase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 6 Craig B. Thompson, Memorial Sloan Kettering Cancer Center, USA Epigenetic Control by Mutant IDH
Tuesday, March 18 \| 8:00AM - 11:15AM Isocitrate Dehydrogenase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 6 Elizabeth Maher, University of Texas Southwestern Medical Center, USA Metabolic Imaging of IDH Mutant Brain Tumors
Tuesday, March 18 \| 8:00AM - 11:15AM Isocitrate Dehydrogenase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 4 of 6 Kate Yen, Auron Therapeutics, USA AG-221 Offers a Survival Advantage in a Primary Human IDH2 Mutant AML Xenograft Model
Tuesday, March 18 \| 8:00AM - 11:15AM Isocitrate Dehydrogenase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 5 of 6 Christian Metallo, University of California, San Diego, USA Short Talk: Exploiting Oncogenic IDH Mutations to Identify Therapeutic Targets and Annotate Compartmentalized Pathway Function
Tuesday, March 18 \| 8:00AM - 11:15AM Isocitrate Dehydrogenase This session is from Tumor Metabolism Room: Sea to Sky C Speaker 6 of 6 Yoko Ogawara, National Cancer Center Research Institute, Japan Short Talk: Critical Roles of the IDH2 Mutation in Development and Maintenance of Acute Myeloid Leukemia
Tuesday, March 18 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Tuesday, March 18 \| 11:15AM - 1:00PM Poster Setup Room: Sea to Sky A
Tuesday, March 18 \| 11:15AM - 5:00PM On Own for Lunch and Recreation
Tuesday, March 18 \| 1:00PM - 10:00PM Poster Viewing Room: Sea to Sky A
Tuesday, March 18 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Tuesday, March 18 \| 5:00PM - 7:00PM Novel Metabolic Pathways in Cancer II Room: Sea to Sky B Speaker 1 of 6 * M. Celeste Simon, University of Pennsylvania, USA
Tuesday, March 18 \| 5:00PM - 7:00PM Novel Metabolic Pathways in Cancer II Room: Sea to Sky B Speaker 2 of 6 James M. Phang, NCI at Frederick, National Institutes of Health, USA The Proline Regulatory Axis: Metabolic Reprogramming in Cancer
Tuesday, March 18 \| 5:00PM - 7:00PM Novel Metabolic Pathways in Cancer II Room: Sea to Sky B Speaker 3 of 6 Yury I. Miller, University of California, San Diego, USA Cholesterol Efflux and Angiogenesis
Tuesday, March 18 \| 5:00PM - 7:00PM Novel Metabolic Pathways in Cancer II Room: Sea to Sky B Speaker 4 of 6 Hwee Ying Lim, National University of Singapore, Singapore Role of Lymphatic Vessels in Cholesterol Clearance and the Involvement of High-Density Lipoproteins in Regulating Lymphatic Function
Tuesday, March 18 \| 5:00PM - 7:00PM Novel Metabolic Pathways in Cancer II Room: Sea to Sky B Speaker 5 of 6 † Natalie Sheng Jie Lim, National University Singapore, Singapore Short Talk: Strategy to Enhance Angiogenesis: A Prolyl Hydroxylase Inhibitor and Lysophospholipid Approach
Tuesday, March 18 \| 5:00PM - 7:00PM Novel Metabolic Pathways in Cancer II Room: Sea to Sky B Speaker 6 of 6 Brian W. Wong, Washington University School of Medicine, USA Short Talk: Investigating the Metabolism of Venous and Lymphatic Endothelial Cells
Tuesday, March 18 \| 5:00PM - 7:00PM Lactate and Monocarboxylate Transporters This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 4 Ubaldo E. Martinez Outschoorn, Thomas Jefferson University/Frontiers, USA Talk Title to be Announced
Tuesday, March 18 \| 5:00PM - 7:00PM Lactate and Monocarboxylate Transporters This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 4 Jacques Pouysségur, University of Nice, France Targeting Lactate/H+ Symporters for Cancer Therapy
Tuesday, March 18 \| 5:00PM - 7:00PM Lactate and Monocarboxylate Transporters This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 4 John Kurhanewicz, University of California, San Francisco, USA Using in Vivo Hyperpolarized 13C MR Imaging for Measuring Metabolic Fluxes Important to Prostate Cancer Progression and Therapeutic Response
Tuesday, March 18 \| 5:00PM - 7:00PM Lactate and Monocarboxylate Transporters This session is from Tumor Metabolism Room: Sea to Sky C Speaker 4 of 4 Sunghee Park, Duke University Medical Center, USA Short Talk: PGC-1alpha/ERRalpha Regulates Lactate-Fueled Mitochondrial Oxidative Metabolism in Breast Cancer
Tuesday, March 18 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Tuesday, March 18 \| 7:30PM - 10:00PM Poster Session 2 Room: Sea to Sky A
Wednesday, March 19 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A
Wednesday, March 19 \| 7:30AM - 8:00AM Poster Setup Room: Sea to Sky A
Wednesday, March 19 \| 8:00AM - 7:00PM Poster Viewing Room: Sea to Sky A
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Anti-Angiogenic Therapy Room: Sea to Sky B Speaker 1 of 6 Dai Fukumura, Massachusetts General Hospital, USA Vascular Normalization and Metabolic Microenvironment
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Anti-Angiogenic Therapy Room: Sea to Sky B Speaker 2 of 6 Patrizia Agostinis, KU Leuven, Belgium Tumor Vessel Normalization by Chloroquine Independent on Autophagy Blockage
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Anti-Angiogenic Therapy Room: Sea to Sky B Speaker 3 of 6 Olivier Feron, Université Catholique de Louvain, Belgium Targeting Lactate and Glutamine Metabolism in Endothelial Cells
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Anti-Angiogenic Therapy Room: Sea to Sky B Speaker 4 of 6 Adrian L. Harris, University of Oxford, Weatherall Institute of Molecular Medicine, UK Metabolic Response to Anti-Angiogenic Therapy
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Anti-Angiogenic Therapy Room: Sea to Sky B Speaker 5 of 6 Guy Eelen, Vesalius Research Center, KU Leuven, Belgium Short Talk: Deletion of Glutamine Synthetase in Endothelial Cells Leads to Vessel Branching Defects
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Anti-Angiogenic Therapy Room: Sea to Sky B Speaker 6 of 6 Stephanie M. Cossette, Medical College of Wisconsin, USA Short Talk: Sucrose Non-Fermenting Related Kinase (SNRK) Is an AMPK Family Member that Is Essential for Cardiac Metabolism in vivo
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Epigenetic Enzymes This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 5 Lucy A. Godley, University of Chicago, USA Regulation of Hematopoiesis by 5-Hydroxymethylcytosine
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Epigenetic Enzymes This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 5 Chuan He, University of Chicago, USA Epigenetic DNA and RNA Demethylation in Mammalian Regulation
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Epigenetic Enzymes This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 5 Anne Brunet, Stanford University, USA Metabolic and Epigenetic Regulation of Aging
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Epigenetic Enzymes This session is from Tumor Metabolism Room: Sea to Sky C Speaker 4 of 5 Paul Guilhamon, University College London Cancer Institute, UK Short Talk: Meta-Analysis of IDH-Mutant Cancers Identifies a New Interaction Partner for TET2
Wednesday, March 19 \| 8:00AM - 11:15AM Metabolism and Epigenetic Enzymes This session is from Tumor Metabolism Room: Sea to Sky C Speaker 5 of 5 Hong-Wu Chen, University of California, Davis, USA Short Talk: Reprogramming Metabolism for Cancer Therapeutic Resistance by Histone Methylases
Wednesday, March 19 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Wednesday, March 19 \| 11:15AM - 12:00PM Lunch Room: Sea to Sky A
Wednesday, March 19 \| 12:00PM - 2:30PM Poster Session 3 Room: Sea to Sky A
Wednesday, March 19 \| 2:30PM - 4:30PM Workshop: Monitoring Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 4 Hilary A. Coller, University of California, Los Angeles, USA Metabolism of Quiescent Cells
Wednesday, March 19 \| 2:30PM - 4:30PM Workshop: Monitoring Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 4 Linda C. Hsieh-Wilson, California Institute of Technology, USA The Interplay of Protein Glycosylation and Cancer Metabolism
Wednesday, March 19 \| 2:30PM - 4:30PM Workshop: Monitoring Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 4 Alan Saghatelian, The Salk Institute for Biological Studies, USA Protein-Metabolite Interactions
Wednesday, March 19 \| 2:30PM - 4:30PM Workshop: Monitoring Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 4 of 4 Sakino Toue, Ajinomoto Co., Inc, Japan Short Talk: MALDI-Imaging Mass Spectrometry Assisted by On-Tissue Chemical Derivatization for Visualizing Multiple Amino Acids in Human Colon Cancer Xenografts
Wednesday, March 19 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Wednesday, March 19 \| 5:00PM - 7:00PM Metabolism and Pathological Angiogenesis Room: Sea to Sky B Speaker 1 of 4 Yoshiaki Kubota, Keio University, Japan Oxidative Stress as a Target for Anti-Angiogenic Therapy
Wednesday, March 19 \| 5:00PM - 7:00PM Metabolism and Pathological Angiogenesis Room: Sea to Sky B Speaker 2 of 4 * Michael Simons, Yale University, USA Vascular Fate Determination
Wednesday, March 19 \| 5:00PM - 7:00PM Metabolism and Pathological Angiogenesis Room: Sea to Sky B Speaker 3 of 4 Massimiliano Mazzone, KU Leuven – VIB, Belgium Influence of Macrophage Metabolism on Vessel Shape: Implications for Cancer
Wednesday, March 19 \| 5:00PM - 7:00PM Metabolism and Pathological Angiogenesis Room: Sea to Sky B Speaker 4 of 4 Tony Walshe, Novartis, USA Short Talk: Mitochondrial Oxidative Phosphorylation and Redox Signaling Govern Endothelial Cell Fate Decisions
Wednesday, March 19 \| 5:00PM - 7:00PM Lipid Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 4 Daniel K. Nomura, University of California, Berkeley, USA Mapping Dyregulated Metabolic Pathways in Cancer Using Functional Proteomic and Metabolomic Platforms
Wednesday, March 19 \| 5:00PM - 7:00PM Lipid Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 4 Gerald Hoefler, Medical University of Graz, Austria Adipose Triglyceride Lipase (ATGL) is a Metabolic Tumor Suppressor Gene
Wednesday, March 19 \| 5:00PM - 7:00PM Lipid Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 4 Ernst R. Lengyel, University of Chicago, USA Crosstalk between Cancer Cells and Adipocytes
Wednesday, March 19 \| 5:00PM - 7:00PM Lipid Metabolism This session is from Tumor Metabolism Room: Sea to Sky C Speaker 4 of 4 Jurre J. Kamphorst, Rheos Medicines, USA Short Talk: Hypoxic and Ras-Transformed Cells Support Growth by Scavenging Fatty Acids from Lysophospholipids
Wednesday, March 19 \| 7:00PM - 7:00PM On Own for Dinner
Thursday, March 20 \| 7:00AM - 8:00AM Breakfast Room: Sea to Sky A
Thursday, March 20 \| 8:00AM - 11:00AM Novel Cancer Metabolic Targets (Joint) Room: Sea to Sky B/C Speaker 1 of 6 Almut Schulze, University of Würzburg/Theodor-Boveri Institute, Germany The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells
Thursday, March 20 \| 8:00AM - 11:00AM Novel Cancer Metabolic Targets (Joint) Room: Sea to Sky B/C Speaker 2 of 6 Jonathan Hurov, Agios Pharmaceuticals, USA Investigation of Glutaminase (GLS1) Dependency in Cancer Cells
Thursday, March 20 \| 8:00AM - 11:00AM Novel Cancer Metabolic Targets (Joint) Room: Sea to Sky B/C Speaker 3 of 6 Thomas O'Brien, Pfizer, USA and
Thursday, March 20 \| 8:00AM - 11:00AM Novel Cancer Metabolic Targets (Joint) Room: Sea to Sky B/C Speaker 4 of 6 Peter K. Jackson, Stanford University, USA Inhibiting Glycolysis with a New LDHA Inhibitor
Thursday, March 20 \| 8:00AM - 11:00AM Novel Cancer Metabolic Targets (Joint) Room: Sea to Sky B/C Speaker 5 of 6 Brooke M. Emerling, Sanford Burnham Prebys Medical Discovery Institute, USA Short Talk: Deletion of Phosphatidylinositol-5-Phosphate 4-Kinases Results in Impaired Growth of p53 Deficient Tumors by Mediating Changes in Metabolism
Thursday, March 20 \| 8:00AM - 11:00AM Novel Cancer Metabolic Targets (Joint) Room: Sea to Sky B/C Speaker 6 of 6 Kristen E.N. Scott, H. Lee Moffitt Cancer Center & Research Institute, USA Short Talk: De Novo Fatty Acid Synthesis Is Regulated by Myc and Is Required for B-Lymphoma Survival
Thursday, March 20 \| 9:20AM - 9:40AM Coffee Break Room: Foyer
Thursday, March 20 \| 11:00AM - 5:00PM On Own for Lunch and Recreation
Thursday, March 20 \| 4:30PM - 5:00PM Coffee Available Room: Foyer
Thursday, March 20 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Therapeutic Implications Room: Sea to Sky B Speaker 1 of 5 * Massimiliano Mazzone, KU Leuven – VIB, Belgium
Thursday, March 20 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Therapeutic Implications Room: Sea to Sky B Speaker 2 of 5 Sara Zanivan, CRUK Beatson Institute, UK Elucidating Endothelial Metabolism Using Quantitative Proteomics
Thursday, March 20 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Therapeutic Implications Room: Sea to Sky B Speaker 3 of 5 Ulrike Harjes, University of Oxford, UK Dll4-Notch and Foxo1 Co-Regulate Endothelial Fatty Acid Binding Protein 4
Thursday, March 20 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Therapeutic Implications Room: Sea to Sky B Speaker 4 of 5 Miguel Quintela-Fandino, Spanish National Cancer Research Centre, Spain Short Talk: Metabolic Synthetic Lethality: Antiangiogenic Treatment Plus Phenformin in Breast Cancer
Thursday, March 20 \| 5:00PM - 7:00PM Metabolism and Angiogenesis: Therapeutic Implications Room: Sea to Sky B Speaker 5 of 5 Anuradha Doddaballapur, Institute of Cardiovascular Regeneration, Germany Short Talk: Shear Stress and Krüppel-Like Factor 2 Regulate Endothelial Metabolism by Repressing PFKFB3
Thursday, March 20 \| 5:00PM - 7:00PM Novel Cancer Metabolic Targets II This session is from Tumor Metabolism Room: Sea to Sky C Speaker 1 of 3 Benjamin F. Cravatt III, The Scripps Research Institute, USA Crosstalk between Metabolic and Signaling Pathways in Cancer
Thursday, March 20 \| 5:00PM - 7:00PM Novel Cancer Metabolic Targets II This session is from Tumor Metabolism Room: Sea to Sky C Speaker 2 of 3 Sandaruwan Geeganage, Eli Lilly and Company, USA Targeting Metabolic Reprogramming for Cancer – A Pharma Perspective
Thursday, March 20 \| 5:00PM - 7:00PM Novel Cancer Metabolic Targets II This session is from Tumor Metabolism Room: Sea to Sky C Speaker 3 of 3 Nissim Hay, University of Illinois at Chicago, USA Targeting Glucose Metabolism for Cancer Therapy
Thursday, March 20 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sea to Sky A
Thursday, March 20 \| 8:00PM - 11:00PM Entertainment Room: Sea to Sky A
Thursday, March 20 \| 8:00PM - 11:00PM Cash Bar Room: Sea to Sky A
Friday, March 21 \| 10:25AM - 10:25AM Departure *Session Chair.