Web Desc
Immunity to Veterinary Pathogens: Informing Vaccine Development
Organizer(s): William T. Golde, Wendy C. Brown and Ivan Morrison
Date: January 20 - 25, 2015
Location: Keystone Resort, Keystone, CO, USA
Supported by the Directors' Fund
For important information on the coronavirus, please click here
Summary of Meeting:
The need for more effective vaccines to protect food animals against infectious diseases has never been greater. Pressures on food sources are predicted to reach a critical state in a few decades, resulting in food shortages, especially in the developing world. While there is a long history of using vaccination to control animal diseases, the most notable success being the eradication of rinderpest, there are many important diseases for which no effective vaccines are available. Advances in genomic technologies, coupled with improved knowledge of the cellular and molecular events involved in the immune response, provide exciting new opportunities for vaccine development. However, effective exploitation of these advances needs to be based on an understanding of the immune responses that mediate effective immunity against the target pathogens. While laboratory animal models have proved invaluable in elucidating fundamental immunological principles, the results of vaccination studies have often failed to translate to larger animal species and humans. Hence, there is a need to study the target diseases in their natural hosts. Animals also provide valuable experimental models for studies of zoonotic pathogens that cause disease in both animals and humans (e.g., TB and influenza), as well as closely related pathogens that cause similar diseases in animals and humans. This meeting seeks to highlight the value of studying immune responses to infectious disease in animals not only to develop control measures for animal diseases but also to advance knowledge that may be more widely applicable for vaccine development. Understanding the immune response in veterinary species holds the promise of accelerating vaccine development for food animals, companion pets and clearly humans, directly addressing the One World, One Health concept emerging in vaccine research.
Scholarship Deadline: September 29 2014
Discounted Abstract Deadline: September 29 2014
Abstract Deadline: October 21 2014
Discounted Registration Deadline: November 19 2014
Abstacts when book is in proofing process


We gratefully acknowledge additional support for this conference from:
Zoetis
We gratefully acknowledge the generous grant for this conference provided by:

US Department of Agriculture (USDA)
Grant No. 2015-67015-22933
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the National Institute of Food and Agriculture, USDA; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, January 20 | 4:00PM - 8:00PM
Arrival and Registration
Room: Keystone Lodge Lobby


Tuesday, January 20 | 6:00PM - 8:00PM
Welcome Mixer
Room: Keystone Lodge-Bighorn Bar
No registration fees are used to fund alcohol served at this function.

Wednesday, January 21 | 7:00AM - 8:00AM
Breakfast
Room: Crestone


Wednesday, January 21 | 8:00AM - 9:00AM
Keynote Address
Room: Red Cloud
Overview of the field of veterinary immunology and the relation of animal health to human health, especially as it relates to infectious diseases.
Speaker 1 of 1
Linda J. Saif, Ohio State University, USA
Gut Reactions to Rotavirus Vaccines: Novel Strategies to Improve Efficacy in Piglets and Infants

Wednesday, January 21 | 9:00AM - 11:15AM
The Role of gamma/delta T Cells in Innate and Acquired Immun
ity

Room: Red Cloud
This session will highlight the unique and informative data being generated on gamma delta T cells in cattle and swine where this cell subset is 30% of PBMC in young animals, compared to 5-10% in humans and are not present in mouse circulating lymphocytes.
Speaker 1 of 6
* Wendy C. Brown, Washington State University, USA

Wednesday, January 21 | 9:00AM - 11:15AM
The Role of gamma/delta T Cells in Innate and Acquired Immun
ity

Room: Red Cloud
This session will highlight the unique and informative data being generated on gamma delta T cells in cattle and swine where this cell subset is 30% of PBMC in young animals, compared to 5-10% in humans and are not present in mouse circulating lymphocytes.
Speaker 2 of 6
* Douglas F. Antczak, Cornell University, USA

Wednesday, January 21 | 9:00AM - 11:15AM
The Role of gamma/delta T Cells in Innate and Acquired Immun
ity

Room: Red Cloud
This session will highlight the unique and informative data being generated on gamma delta T cells in cattle and swine where this cell subset is 30% of PBMC in young animals, compared to 5-10% in humans and are not present in mouse circulating lymphocytes.
Speaker 3 of 6
Mark Jutila, Montana State University, USA
Enhancing the Innate Lymphocyte Response with Plant and Microbial Products

Wednesday, January 21 | 9:00AM - 11:15AM
The Role of gamma/delta T Cells in Innate and Acquired Immun
ity

Room: Red Cloud
This session will highlight the unique and informative data being generated on gamma delta T cells in cattle and swine where this cell subset is 30% of PBMC in young animals, compared to 5-10% in humans and are not present in mouse circulating lymphocytes.
Speaker 4 of 6
Randy E. Sacco, National Animal Disease Center, US Department of Agriculture, USA
Influence of gammadelta T Cells on the Immunopathology of Bovine Respiratory Syncytial Virus

Wednesday, January 21 | 9:00AM - 11:15AM
The Role of gamma/delta T Cells in Innate and Acquired Immun
ity

Room: Red Cloud
This session will highlight the unique and informative data being generated on gamma delta T cells in cattle and swine where this cell subset is 30% of PBMC in young animals, compared to 5-10% in humans and are not present in mouse circulating lymphocytes.
Speaker 5 of 6
Janice C. Telfer, University of Massachusetts, USA
WC1 Is a Hybrid gammadelta TCR Coreceptor and Pattern Recognition Receptor for Pathogenic Bacteria

Wednesday, January 21 | 9:00AM - 11:15AM
The Role of gamma/delta T Cells in Innate and Acquired Immun
ity

Room: Red Cloud
This session will highlight the unique and informative data being generated on gamma delta T cells in cattle and swine where this cell subset is 30% of PBMC in young animals, compared to 5-10% in humans and are not present in mouse circulating lymphocytes.
Speaker 6 of 6
Efrain Guzman, Pirbright Institute, UK
Short Talk: Bovine gamma delta T Cells Are a Major Regulatory T Cell Subset

Wednesday, January 21 | 9:40AM - 10:00AM
Coffee Break
Room: Crestone Foyer


Wednesday, January 21 | 11:15AM - 1:00PM
Poster Setup
Room: Crestone


Wednesday, January 21 | 11:15AM - 2:30PM
On Own for Lunch


Wednesday, January 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Crestone


Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 1 of 8
* Dirk Werling, Royal Veterinary College, UK

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 2 of 8
* Paul M. Coussens, Michigan State University, USA

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 3 of 8
Ellis J. Powell, USDA ARS, USA
Increased Percentages of Functional NK Cells in Pigs with Severe Combined Immune Deficiency (SCID) Caused by Natural Mutations in the Artemis Gene

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 4 of 8
Bianca Libanori Artiaga, University of Florida, USA
Targeting NKT Cells to Enhance Immunity: A Novel Swine Model

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 5 of 8
Tomohiro Okagawa, Hokkaido University, Japan
A Novel Strategy for Immunotherapy of Paratuberculosis in Cattle: Regulation of T-Cell Response to Mycobacterium avium subspecies paratuberculosis by the Blockade of Immunoinhibitory Receptors

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 6 of 8
Satoru Konnai, Hokkaido University, Japan
Increases of Cells Expressing PD-1 and PD-L1 in Bovine Leukemia Virus Infection and Enhancement of Anti-Viral Immune Responses in vitro via its Blockade

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 7 of 8
Michael C. Rahe, University of Minnesota, USA
Cytokine-Mediated Proliferation and Differentiation of Porcine B Cells into Ig Secreting Plasma Cells

Wednesday, January 21 | 2:30PM - 4:30PM
Workshop 1: Immune Function and Regulation
Room: Red Cloud

Speaker 8 of 8
Mark S. Fife, Pirbright Institute, UK
Chicken Interferon-Inducible Transmembrane (IFITM) Proteins Are Functional and Actively Restrict Avian Viruses

Wednesday, January 21 | 4:30PM - 5:00PM
Coffee Available
Room: Crestone Foyer


Wednesday, January 21 | 5:00PM - 7:00PM
Innate Responses to Infection
Room: Red Cloud
The early and often effective immune response to infection as well as to adjuvants in vaccine formulations is mediated by the cells of the innate immune system including dendritic cells, natural killer (NK) cells and gamma/delta T cells. This session will focus on DCs and NK as another session focuses on the gamma delta T cells.
Speaker 1 of 6
* William T. Golde, Moredun Research Institute, UK

Wednesday, January 21 | 5:00PM - 7:00PM
Innate Responses to Infection
Room: Red Cloud
The early and often effective immune response to infection as well as to adjuvants in vaccine formulations is mediated by the cells of the innate immune system including dendritic cells, natural killer (NK) cells and gamma/delta T cells. This session will focus on DCs and NK as another session focuses on the gamma delta T cells.
Speaker 2 of 6
* Cynthia L. Baldwin, University of Massachusetts, USA

Wednesday, January 21 | 5:00PM - 7:00PM
Innate Responses to Infection
Room: Red Cloud
The early and often effective immune response to infection as well as to adjuvants in vaccine formulations is mediated by the cells of the innate immune system including dendritic cells, natural killer (NK) cells and gamma/delta T cells. This session will focus on DCs and NK as another session focuses on the gamma delta T cells.
Speaker 3 of 6
Artur Summerfield, Institute of Virology and Immunology, Switzerland
Plasmacytoid Dendritic Cells in the Early Response to Infection

Wednesday, January 21 | 5:00PM - 7:00PM
Innate Responses to Infection
Room: Red Cloud
The early and often effective immune response to infection as well as to adjuvants in vaccine formulations is mediated by the cells of the innate immune system including dendritic cells, natural killer (NK) cells and gamma/delta T cells. This session will focus on DCs and NK as another session focuses on the gamma delta T cells.
Speaker 4 of 6
John A. Hammond, Pirbright Institute, UK
Genetics of Natural Killer Cell Receptors in Cattle

Wednesday, January 21 | 5:00PM - 7:00PM
Innate Responses to Infection
Room: Red Cloud
The early and often effective immune response to infection as well as to adjuvants in vaccine formulations is mediated by the cells of the innate immune system including dendritic cells, natural killer (NK) cells and gamma/delta T cells. This session will focus on DCs and NK as another session focuses on the gamma delta T cells.
Speaker 5 of 6
David A. Hume, University of Edinburgh, UK
The Role of Macrophages in Innate Immunity following Infection

Wednesday, January 21 | 5:00PM - 7:00PM
Innate Responses to Infection
Room: Red Cloud
The early and often effective immune response to infection as well as to adjuvants in vaccine formulations is mediated by the cells of the innate immune system including dendritic cells, natural killer (NK) cells and gamma/delta T cells. This session will focus on DCs and NK as another session focuses on the gamma delta T cells.
Speaker 6 of 6
Dirk Werling, Royal Veterinary College, UK
Short Talk: Differences in Inflammasome Activation between Cow Breeds Impact on Bacterial Killing

Wednesday, January 21 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Crestone
No registration fees are used to fund alcohol served at this function.

Wednesday, January 21 | 7:30PM - 10:00PM
Poster Session 1
Room: Crestone


Thursday, January 22 | 7:00AM - 8:00AM
Breakfast
Room: Crestone


Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 1 of 7
* Randy E. Sacco, National Animal Disease Center, US Department of Agriculture, USA

Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 2 of 7
* Gregers Jungersen, Technical University of Denmark, Denmark

Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 3 of 7
David W. Pascual, University of Florida, USA
Mucosal Vaccines for Brucellosis

Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 4 of 7
Crystal L. Loving, US Department of Agriculture, ARS, National Animal Disease Center, USA
Provocation versus Protection – Immune Responses and Differential Outcomes following Influenza Virus Vaccination and Challenge in Pigs

Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 5 of 7
Massimo Amadori, Istituto Zooprofilattico Sperimentale della Lombardia e dell’Emilia-Romagna, Italy
Immunoprophylaxis in Intensive Farming Systems: The Way Forward

Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 6 of 7
Armin Saalmüller, Inst Immunology, University Veterinary Medicine, Veinna, Austria
Immune Response of Porcine CD4+ T Cells following Infection with Influenza- or PRRS Virus

Thursday, January 22 | 8:00AM - 11:00AM
Mucosal Immune Responses to Infection
Room: Red Cloud
This session will explore the unique aspects of mucosal immune responses to infections with enteric and respiratory pathogens.
Speaker 7 of 7
Heidi Mikkelsen, National Veterinary Institute, Technical University of Denmark, Denmark
Short Talk: Vaccination with Peptides of Mycobacterium avium subspecies paratuberculosis (MAP) Reduces MAP Burden of Infected Goats

Thursday, January 22 | 9:20AM - 9:40AM
Coffee Break
Room: Crestone Foyer


Thursday, January 22 | 11:00AM - 1:00PM
Poster Setup
Room: Crestone


Thursday, January 22 | 11:00AM - 5:00PM
On Own for Lunch


Thursday, January 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Crestone


Thursday, January 22 | 4:30PM - 5:00PM
Coffee Available
Room: Crestone Foyer


Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 1 of 7
* Armin Saalmüller, Inst Immunology, University Veterinary Medicine, Veinna, Austria

Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 2 of 7
* David W. Pascual, University of Florida, USA

Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 3 of 7
Kristien Van Reeth, Universiteit Ghent, Belgium
Cross-Protection Studies with Diverse Swine Influenza Viruses: A Case for Revising Cross-Protective Immunity between Influenza A Viruses

Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 4 of 7
María Montoya, Centre de Recerca en Sanitat Animal and The Pirbright Institute, UK
Immune Response to Influenza Infection of Swine, Friend or Foe?

Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 5 of 7
Jesús Hernández, Centro de Investigación en Alimentación y Desarrollo, Mexico
Influenza Transmission in Swine and Birds

Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 6 of 7
Ignacio Mena, Icahn School of Medicine at Mount Sinai, USA
Short Talk: Recombinant Newcastle Disease Viruses Expressing swine and Avian Influenza Hemagglutinins Induce Protective Antibody Responses in Pigs and Chickens

Thursday, January 22 | 5:00PM - 7:15PM
Immune Responses to Swine and Avian Influenza
Room: Red Cloud
Understanding the immunopathology and epidemiology of influenza infections in reservoir species is central to the design and deployment of new vaccines to control this zoonotic disease.
Speaker 7 of 7
Elma Z. Tchilian, Pirbright Institute, UK
Short Talk: Immune Responses to a Candidate Universal Influenza Vaccine in Pigs

Thursday, January 22 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Crestone
No registration fees are used to fund alcohol served at this function.

Thursday, January 22 | 7:30PM - 10:00PM
Poster Session 2
Room: Crestone


Friday, January 23 | 7:00AM - 8:00AM
Breakfast
Room: Crestone


Friday, January 23 | 8:00AM - 11:00AM
Analysis of Immune Responses to Vector-Borne Pathogens
Room: Red Cloud
Arthropod borne diseases have a unique landscape of immunopathology and immune responses that will be highlighted in this session. For the livestock diseases, there are major adverse impacts on populations in tropical, developing countries and loss of livestock results in severe effects on food sources in these regions.
Speaker 1 of 6
* Samuel James Black, University of Massachusetts, USA

Friday, January 23 | 8:00AM - 11:00AM
Analysis of Immune Responses to Vector-Borne Pathogens
Room: Red Cloud
Arthropod borne diseases have a unique landscape of immunopathology and immune responses that will be highlighted in this session. For the livestock diseases, there are major adverse impacts on populations in tropical, developing countries and loss of livestock results in severe effects on food sources in these regions.
Speaker 2 of 6
* Vish Nene, International Livestock Research Institute, Kenya

Friday, January 23 | 8:00AM - 11:00AM
Analysis of Immune Responses to Vector-Borne Pathogens
Room: Red Cloud
Arthropod borne diseases have a unique landscape of immunopathology and immune responses that will be highlighted in this session. For the livestock diseases, there are major adverse impacts on populations in tropical, developing countries and loss of livestock results in severe effects on food sources in these regions.
Speaker 3 of 6
Ivan Morrison, University of Edinburgh, UK
CD8 T Cells Mediate Immunity in Cattle that Survive Infections with Theileria parva

Friday, January 23 | 8:00AM - 11:00AM
Analysis of Immune Responses to Vector-Borne Pathogens
Room: Red Cloud
Arthropod borne diseases have a unique landscape of immunopathology and immune responses that will be highlighted in this session. For the livestock diseases, there are major adverse impacts on populations in tropical, developing countries and loss of livestock results in severe effects on food sources in these regions.
Speaker 4 of 6
Jayne Raper, Hunter College, USA
Introducing Genetic Resistance for Trypanasomiasis into Sheep and Cattle

Friday, January 23 | 8:00AM - 11:00AM
Analysis of Immune Responses to Vector-Borne Pathogens
Room: Red Cloud
Arthropod borne diseases have a unique landscape of immunopathology and immune responses that will be highlighted in this session. For the livestock diseases, there are major adverse impacts on populations in tropical, developing countries and loss of livestock results in severe effects on food sources in these regions.
Speaker 5 of 6
Robert H. Mealey, Washington State University, USA
Challenges Facing Chemotherapeutic and Immune Control of Theileria equi

Friday, January 23 | 8:00AM - 11:00AM
Analysis of Immune Responses to Vector-Borne Pathogens
Room: Red Cloud
Arthropod borne diseases have a unique landscape of immunopathology and immune responses that will be highlighted in this session. For the livestock diseases, there are major adverse impacts on populations in tropical, developing countries and loss of livestock results in severe effects on food sources in these regions.
Speaker 6 of 6
Wendy C. Brown, Washington State University, USA
Dysfunctional CD4 T-Cell Responses during Anaplasma marginale Infection

Friday, January 23 | 9:20AM - 9:40AM
Coffee Break
Room: Crestone Foyer


Friday, January 23 | 11:00AM - 1:00PM
Poster Setup
Room: Crestone


Friday, January 23 | 11:00AM - 2:30PM
On Own for Lunch


Friday, January 23 | 1:00PM - 10:00PM
Poster Viewing
Room: Crestone


Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 1 of 9
* W. Ray Waters, National Animal Disease Center, USA

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 2 of 9
* Timothy Connelley, University of Edinburgh, UK

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 3 of 9
Elizabeth Rieder, Agricultural Research Service, US Department of Agriculture, USA
Marker Foot-and-Mouth Disease Vaccine Platform: A Safe and Potentially Low-Cost Option for Global Production of Inactivated FMDV Vaccines

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 4 of 9
Douglas F. Antczak, Cornell University, USA
Identification of Peptide Motifs for Equine Major Histocompatibility Complex Class I Molecules

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 5 of 9
Mital Pandya, University of Vermont, USA
Identification of Peptides from Foot-and-Mouth Disease Virus Structural Proteins Bound by Bovine Leukocyte Antigen (BoLA) Class I Molecules

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 6 of 9
Simon Welner, National Veterinary Institute, Technical University of Denmark, Denmark
Bioinformatics Prediction of Swine MHC Class I Epitopes from Porcine Reproductive and Respiratory Syndrome Virus

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 7 of 9
Jean-Pierre Y. Scheerlinck, University of Melbourne, Australia
Immune Memory Resilience, a New Way of Evaluating Adjuvants

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 8 of 9
Charlotte R. Bell, Roslin Institute, University of Edinburgh, UK
Haematopoietic Depletion in Vaccine-Induced Bovine Neonatal Pancytopenia (BNP) Depends on the Titre and Specificity of Alloantibody and Levels of MHC I Expression

Friday, January 23 | 2:30PM - 4:30PM
Workshop 2: Antigen Identification and Vaccine Formulation
Room: Red Cloud

Speaker 9 of 9
Preben Boysen, Norwegian University of Life Sciences, Norway
Transient Recruitment of Inflammatory Monocytes and Early Activation of Lymphocytes in the Draining Lymph Node of Calves following Injection of a Saponin-Based Adjuvant

Friday, January 23 | 4:30PM - 5:00PM
Coffee Available
Room: Crestone Foyer


Friday, January 23 | 5:00PM - 7:00PM
Immunodeficiency Virus Infections in Veterinary Species
Room: Red Cloud
Originally described in veterinary species, the study of immunodeficiency viruses has been greatly aided by studying these infections in cats, monkeys and horses.
Speaker 1 of 6
* Christopher K. Tuggle, Iowa State University, USA

Friday, January 23 | 5:00PM - 7:00PM
Immunodeficiency Virus Infections in Veterinary Species
Room: Red Cloud
Originally described in veterinary species, the study of immunodeficiency viruses has been greatly aided by studying these infections in cats, monkeys and horses.
Speaker 2 of 6
* Jayne Raper, Hunter College, USA

Friday, January 23 | 5:00PM - 7:00PM
Immunodeficiency Virus Infections in Veterinary Species
Room: Red Cloud
Originally described in veterinary species, the study of immunodeficiency viruses has been greatly aided by studying these infections in cats, monkeys and horses.
Speaker 3 of 6
Simon M. Barratt-Boyes, University of Pittsburgh, USA
Immunopathology of Simian Immunodeficiency Virus Infection

Friday, January 23 | 5:00PM - 7:00PM
Immunodeficiency Virus Infections in Veterinary Species
Room: Red Cloud
Originally described in veterinary species, the study of immunodeficiency viruses has been greatly aided by studying these infections in cats, monkeys and horses.
Speaker 4 of 6
Hannah J. Barbian, University of Pennsylvania, USA
Short Talk: Broad and Potent Neutralization of Simian Immunodeficiency Viruses from Chimpanzees and Gorillas by Host Receptor Antibodies and CD4 Immunoadhesins

Friday, January 23 | 5:00PM - 7:00PM
Immunodeficiency Virus Infections in Veterinary Species
Room: Red Cloud
Originally described in veterinary species, the study of immunodeficiency viruses has been greatly aided by studying these infections in cats, monkeys and horses.
Speaker 5 of 6
Sue VandeWoude, Colorado State University, USA
Antibody Repertoire following Feline Immunodeficiency Virus Infection and Novel Vaccine Delivery

Friday, January 23 | 5:00PM - 7:00PM
Immunodeficiency Virus Infections in Veterinary Species
Room: Red Cloud
Originally described in veterinary species, the study of immunodeficiency viruses has been greatly aided by studying these infections in cats, monkeys and horses.
Speaker 6 of 6
Mia J. Smith, Colorado State University, USA
Short Talk: A Novel Viral Immune Evasion Mechanism Suppresses the PI3-Kinase Signaling Pathway by Induction of Expression of PTEN in B Cells

Friday, January 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Crestone
No registration fees are used to fund alcohol served at this function.

Friday, January 23 | 7:30PM - 10:00PM
Poster Session 3
Room: Crestone


Saturday, January 24 | 7:00AM - 8:00AM
Breakfast
Room: Crestone


Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 1 of 8
* John Barlow, University of Vermont, USA

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 2 of 8
* Chris Chase, South Dakota State University, USA

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 3 of 8
H. Martin Vordermeier, Animal Health & Veterinary Laboratories Agency, UK
Antigen Mining Strategies to Identify Diagnostic and Sub-Unit Vaccine Antigens of Protective of Mycobacterium bovis: Successes and Challenges

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 4 of 8
Paul M. Coussens, Michigan State University, USA
Immune Dysregulation and Regulatory T Cell Responses of Cattle to Infection with Mycobacterium avium subspecies paratuberculosis

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 5 of 8
Gregers Jungersen, Technical University of Denmark, Denmark
Short Talk: A Recombinant Multi-Stage Vaccine against Paratuberculosis Significantly Reduces Bacterial Level in Tissues without Interference in Diagnostics

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 6 of 8
Kumudika I. de Silva, University of Sydney, Australia
Short Talk: CD4+ T Cells, gammadelta T Cells and B Cells Are Associated with Non-Responsiveness to Vaccination in Mycobacterium avium subspecies paratuberculosis Infection

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 7 of 8
Jayne C. Hope, University of Edinburgh, UK
Innate Immune Responses and Bovine Tuberculosis

Saturday, January 24 | 8:00AM - 11:15AM
Immune Responses to Mycobacterium Infection
Room: Red Cloud
Bovine tuberculosis is a cause of significant morbidity and mortality in cattle in developing countries and is also zoonotic for the farmer. Control of M. bovis and other mycobacterial infections is a high priority to elevating small holder farmers to more stable food and income sources. Speakers in this session will address recent work analyzing innate and adaptive immune responses to these infections.
Speaker 8 of 8
W. Ray Waters, National Animal Disease Center, USA
Vaccine Approaches for Bovine Tuberculosis: Correlates of Protection and Relevance to Human Tuberculosis

Saturday, January 24 | 9:20AM - 9:40AM
Coffee Break
Room: Crestone Foyer


Saturday, January 24 | 11:15AM - 5:00PM
On Own for Lunch


Saturday, January 24 | 4:30PM - 5:00PM
Coffee Available
Room: Crestone Foyer


Saturday, January 24 | 5:00PM - 6:45PM
Veterinary Vaccines for the 21st Century
Room: Red Cloud
This session will highlight new, cutting-edge approaches to designing vaccines for livestock and new technologies to assess vaccine performance that will lead to the accelerated development of veterinary vaccines.
Speaker 1 of 5
* Ivan Morrison, University of Edinburgh, UK

Saturday, January 24 | 5:00PM - 6:45PM
Veterinary Vaccines for the 21st Century
Room: Red Cloud
This session will highlight new, cutting-edge approaches to designing vaccines for livestock and new technologies to assess vaccine performance that will lead to the accelerated development of veterinary vaccines.
Speaker 2 of 5
* Linda J. Saif, Ohio State University, USA

Saturday, January 24 | 5:00PM - 6:45PM
Veterinary Vaccines for the 21st Century
Room: Red Cloud
This session will highlight new, cutting-edge approaches to designing vaccines for livestock and new technologies to assess vaccine performance that will lead to the accelerated development of veterinary vaccines.
Speaker 3 of 5
William T. Golde, Moredun Research Institute, UK
Analysis of the Adaptive Immune Response to Foot-and-Mouth Disease Virus (FMDV) following Infection or Vaccination of Cattle or Swine

Saturday, January 24 | 5:00PM - 6:45PM
Veterinary Vaccines for the 21st Century
Room: Red Cloud
This session will highlight new, cutting-edge approaches to designing vaccines for livestock and new technologies to assess vaccine performance that will lead to the accelerated development of veterinary vaccines.
Speaker 4 of 5
Timothy Connelley, University of Edinburgh, UK
Tracking T-Cell Responses at a Clonal Level following T. parva Infection

Saturday, January 24 | 5:00PM - 6:45PM
Veterinary Vaccines for the 21st Century
Room: Red Cloud
This session will highlight new, cutting-edge approaches to designing vaccines for livestock and new technologies to assess vaccine performance that will lead to the accelerated development of veterinary vaccines.
Speaker 5 of 5
Vish Nene, International Livestock Research Institute, Kenya
Design of Recombinant Vaccines for East Coast Fever (ECF) via Reverse Immunology

Saturday, January 24 | 6:45PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Red Cloud


Saturday, January 24 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Crestone
No registration fees are used to fund alcohol served at this function.

Saturday, January 24 | 8:00PM - 11:00PM
Entertainment
Room: Crestone
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Saturday, January 24 | 8:00PM - 11:00PM
Cash Bar
Room: Crestone


Sunday, January 25 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.