Autoimmunity and Tolerance

Organizer(s): Jane L. Grogan, Joanne L. Viney and Gerald T. Nepom

Sponsored by AbbVie Inc., AstraZeneca, BioLegend, Inc., Genentech, Inc., NeoStem, Inc. and Novo Nordisk A/S

Summary of Meeting:

Understanding immune regulation in autoimmunity and tolerance is important for delivering therapies to patients with uncontrolled autoimmune disease. Therefore, the goal of this Keystone Symposia meeting is to bring together scientists and clinicians to discuss what we are learning from pre-clinical mouse models and patient studies. In this regard, the past decade has seen the translation of our fundamental understanding of the immune response into clinical studies, with some success and also some failures. These clinical outcomes, coupled with more sophisticated techniques available to interrogate the human immune response, allow us to reassess and further explore pathways that are driving autoimmune disease. In this symposium, we cover the pathways in immunity and tolerance that lead to loss of immunological control, dysregulated immune responses and chronic inflammatory disease. We cover preclinical and clinical aspects of a diverse number of autoimmune and inflammatory diseases including lupus, multiple sclerosis, inflammatory bowel disease, psoriasis, transplantation and rheumatoid arthritis. Each session is designed to include a basic research talk followed by a mechanistic talk on mouse and human and clinical translation.

Scholarship Deadline: October 2 2014

Discounted Abstract Deadline: October 2 2014

Abstract Deadline: November 4 2014

Discounted Registration Deadline: December 3 2014

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

We gratefully acknowledge additional support for this conference from:

We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Amgen Inc.

Biogen Idec

Genentech, Inc.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI114057-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

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Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

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