Web Desc
Neuroepigenetics
Organizer(s): Hongjun Song and Li-Huei Tsai
Date: February 22 - 26, 2015
Location: Eldorado Hotel & Spa, Santa Fe, NM, USA
Supported by the Directors' Fund
Summary of Meeting:
Following the completion of the Human Genome Project, much of biology’s focus has shifted from the raw sequence of genes to their regulation over time and in response to environmental stimuli, in which epigenetics represents a core mechanism. To date, an increasing body of evidence has surfaced indicating that multiple neurological disorders are, in part, caused by aberrant epigenetic modifications. While tremendous progress has been made in understanding epigenetic regulation of gene expression in the nervous system, researchers have yet to learn how the neural epigenome responds to positive (such as learning experiences, enriched environment) and negative (such as epilepsy, injury, stroke) signals as a whole and at the individual gene level, and how the epigenome is regulated at the molecular level. This knowledge is important to better understand normal brain development, plasticity and function and how the epigenome becomes malfunctioned in diseases. Different from proliferating cells commonly studied in epigegenetics, one major subject of the emerging new field of neuroepigenetics deals with various post-mitotic neurons. This Keystone Symposia meeting aims to bring together experts and pioneers in studying neuroepigenetics to provide an up-to-date and comprehensive picture of epigenetic mechanisms in neural development, plasticity, neuronal function and dysfunction. The program for this meeting is highly likely to attract a wide variety of investigators, many of whom might not otherwise interact.
Scholarship Deadline: October 21 2014
Discounted Abstract Deadline: October 21 2014
Abstract Deadline: November 19 2014
Discounted Registration Deadline: December 18 2014
We gratefully acknowledge additional support for this conference from:
Abcam plc
$1 - $2,499

neurogenetics (published by Springer)
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
neurogenetics (published by Springer)NeuroscientistNews
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Neurological Disorders and Stroke (NINDS)
Grant No. 1R13NS090818-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, February 22 | 4:00PM - 8:00PM
Arrival and Registration
Room: Eldorado Lobby


Sunday, February 22 | 6:00PM - 8:00PM
Welcome Mixer
Room: Zia Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, February 23 | 7:00AM - 8:00AM
Breakfast
Room: Zia Ballroom


Monday, February 23 | 7:30AM - 8:00AM
Poster Setup
Room: Zia Ballroom


Monday, February 23 | 8:00AM - 5:00PM
Poster Viewing
Room: Zia Ballroom


Monday, February 23 | 8:00AM - 9:40AM
Keynote Session
Room: Anasazi Ballroom

Speaker 1 of 4
* Hongjun Song, University of Pennsylvania, USA

Monday, February 23 | 8:00AM - 9:40AM
Keynote Session
Room: Anasazi Ballroom

Speaker 2 of 4
Fred H. Gage, The Salk Institute for Biological Studies, USA
Somatic Mosaicism in the Human Brain

Monday, February 23 | 8:00AM - 9:40AM
Keynote Session
Room: Anasazi Ballroom

Speaker 3 of 4
* Li-Huei Tsai, Massachusetts Institute of Technology, USA

Monday, February 23 | 8:00AM - 9:40AM
Keynote Session
Room: Anasazi Ballroom

Speaker 4 of 4
Michael E. Greenberg, Harvard Medical School, USA
Signaling Networks that Regulate Synapse Development and Cognitive Function

Monday, February 23 | 9:40AM - 10:00AM
Coffee Break
Room: Zia Concourse


Monday, February 23 | 10:00AM - 11:45AM
Epigenetic Mechanisms in Embryonic Development of the Nervou
s System

Room: Anasazi Ballroom

Speaker 1 of 4
* Lisa M. Monteggia, University of Texas Southwestern Medical Center, USA

Monday, February 23 | 10:00AM - 11:45AM
Epigenetic Mechanisms in Embryonic Development of the Nervou
s System

Room: Anasazi Ballroom

Speaker 2 of 4
Antonella Riccio, University College London, UK
Epigenetic Mechanisms of Neuronal Development

Monday, February 23 | 10:00AM - 11:45AM
Epigenetic Mechanisms in Embryonic Development of the Nervou
s System

Room: Anasazi Ballroom

Speaker 3 of 4
Peng Jin, Emory University School of Medicine, USA
Tet-Mediated Active DNA Demethylation in Neurogenesis

Monday, February 23 | 10:00AM - 11:45AM
Epigenetic Mechanisms in Embryonic Development of the Nervou
s System

Room: Anasazi Ballroom

Speaker 4 of 4
Jürgen A. Knoblich, Institute of Molecular Biotechnology, Austria
Proliferation Control and Tumorigenesis in Neural Stem Cell Lineages

Monday, February 23 | 11:45AM - 12:45PM
Lunch
Room: Zia Ballroom


Monday, February 23 | 12:15PM - 2:30PM
Poster Session 1
Room: Zia Ballroom


Monday, February 23 | 2:30PM - 3:30PM
Workshop 1: NIH Grants
Room: Anasazi Ballroom

Speaker 1 of 3
* Hongjun Song, University of Pennsylvania, USA

Monday, February 23 | 2:30PM - 3:30PM
Workshop 1: NIH Grants
Room: Anasazi Ballroom

Speaker 2 of 3
Robert D. Riddle, NINDS, National Institutes of Health, USA

Monday, February 23 | 2:30PM - 3:30PM
Workshop 1: NIH Grants
Room: Anasazi Ballroom

Speaker 3 of 3
Andrea C. Beckel-Mitchener, NIMH, National Institutes of Health, USA

Monday, February 23 | 3:30PM - 4:30PM
Workshop 2: High-Throughput Sequencing for Neuroepigenetics
Room: Anasazi Ballroom

Speaker 1 of 4
* Kinichi Nakashima, Kyushu University, Japan

Monday, February 23 | 3:30PM - 4:30PM
Workshop 2: High-Throughput Sequencing for Neuroepigenetics
Room: Anasazi Ballroom

Speaker 2 of 4
Menno P. Creyghton, Hubrecht Institute, Netherlands
Charting Enhancer Networks in the Human and Non-Human Primate Brain

Monday, February 23 | 3:30PM - 4:30PM
Workshop 2: High-Throughput Sequencing for Neuroepigenetics
Room: Anasazi Ballroom

Speaker 3 of 4
Matthew A. Lalli, University of California, Santa Barbara, USA
Transcriptome Profiling of Williams Syndrome iPSC Neurodevelopment Reveals a Critical Defect in Cell-Cycle Exit of Neural Stem Cells

Monday, February 23 | 3:30PM - 4:30PM
Workshop 2: High-Throughput Sequencing for Neuroepigenetics
Room: Anasazi Ballroom

Speaker 4 of 4
Tie-Yuan Zhang, Douglas Mental Health University Institute, McGill University, Canada
Next-Generation Sequencing Analysis Indicates Maternal Care Differentially Influences Epigenomic Regulation in the Hippocampal Dentate Gyrus of Rats

Monday, February 23 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Monday, February 23 | 5:00PM - 7:00PM
Epigenetic Mechanisms in Adult Neurogenesis
Room: Anasazi Ballroom

Speaker 1 of 6
* Isabelle M. Mansuy, University and ETH Zürich, Switzerland

Monday, February 23 | 5:00PM - 7:00PM
Epigenetic Mechanisms in Adult Neurogenesis
Room: Anasazi Ballroom

Speaker 2 of 6
Jeffrey S. Nye, Johnson & Johnson, USA
Translation of Neuroepigenetics Discoveries to Neurotherapeutics: An Industry Perspective

Monday, February 23 | 5:00PM - 7:00PM
Epigenetic Mechanisms in Adult Neurogenesis
Room: Anasazi Ballroom

Speaker 3 of 6
Xiang-Dong Fu, University of California, San Diego, USA
Critical Barriers for Neuronal Induction and Maturation in Human Cells

Monday, February 23 | 5:00PM - 7:00PM
Epigenetic Mechanisms in Adult Neurogenesis
Room: Anasazi Ballroom

Speaker 4 of 6
Vidya Ramesh, Helmholtz Center Munich, Germany
Short Talk: Uhrf1/Np95 Acts a Key Regulator of Neural Stem Cell Differentiation in vivo

Monday, February 23 | 5:00PM - 7:00PM
Epigenetic Mechanisms in Adult Neurogenesis
Room: Anasazi Ballroom

Speaker 5 of 6
Anne Schaefer, Mount Sinai School of Medicine, USA
Short Talk: Epigenetic Control of Neuronal Specification and Function by PRC2

Monday, February 23 | 5:00PM - 7:00PM
Epigenetic Mechanisms in Adult Neurogenesis
Room: Anasazi Ballroom

Speaker 6 of 6
Sika Zheng, University of California, Riverside, USA
Short Talk: Alternative Splicing Reprogramming during Neuronal Maturation

Monday, February 23 | 7:00PM - 7:00PM
On Own for Dinner


Tuesday, February 24 | 7:00AM - 8:00AM
Breakfast
Room: Zia Ballroom


Tuesday, February 24 | 8:00AM - 11:00AM
Epigenetic Mechanisms Regulating Synapse Formation, Plastici
ty and Behavior

Room: Anasazi Ballroom

Speaker 1 of 6
* Michael E. Greenberg, Harvard Medical School, USA

Tuesday, February 24 | 8:00AM - 11:00AM
Epigenetic Mechanisms Regulating Synapse Formation, Plastici
ty and Behavior

Room: Anasazi Ballroom

Speaker 2 of 6
Li-Huei Tsai, Massachusetts Institute of Technology, USA
A Novel Mechanism Regulating the Expression of Early Response Genes in Neurons

Tuesday, February 24 | 8:00AM - 11:00AM
Epigenetic Mechanisms Regulating Synapse Formation, Plastici
ty and Behavior

Room: Anasazi Ballroom

Speaker 3 of 6
J. David Sweatt, University of Alabama at Birmingham, USA
Epigenetic Mechanisms in Associative Conditioning

Tuesday, February 24 | 8:00AM - 11:00AM
Epigenetic Mechanisms Regulating Synapse Formation, Plastici
ty and Behavior

Room: Anasazi Ballroom

Speaker 4 of 6
Lisa M. Monteggia, University of Texas Southwestern Medical Center, USA
Analysis of the Unique Roles of Individual HDACs in Behavior and Synaptic Plasticity

Tuesday, February 24 | 8:00AM - 11:00AM
Epigenetic Mechanisms Regulating Synapse Formation, Plastici
ty and Behavior

Room: Anasazi Ballroom

Speaker 5 of 6
Hongjun Song, University of Pennsylvania, USA
Activity-Induced Epigenetic Mechanisms in Synaptic and Behavior Plasticity

Tuesday, February 24 | 8:00AM - 11:00AM
Epigenetic Mechanisms Regulating Synapse Formation, Plastici
ty and Behavior

Room: Anasazi Ballroom

Speaker 6 of 6
Timothy Bredy, University of Queensland, Australia
Short Talk: Epitranscriptomic Mechanisms of Memory Stability

Tuesday, February 24 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Tuesday, February 24 | 11:00AM - 1:00PM
Poster Setup
Room: Zia Ballroom


Tuesday, February 24 | 11:00AM - 5:00PM
On Own for Lunch


Tuesday, February 24 | 1:00PM - 10:00PM
Poster Viewing
Room: Zia Ballroom


Tuesday, February 24 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Tuesday, February 24 | 5:00PM - 7:00PM
Molecular Mechanisms
Room: Anasazi Ballroom

Speaker 1 of 4
Isabelle M. Mansuy, University and ETH Zürich, Switzerland
Non-Genetic Inheritance of the Impact of Traumatic Stress across Generations in Mice

Tuesday, February 24 | 5:00PM - 7:00PM
Molecular Mechanisms
Room: Anasazi Ballroom

Speaker 2 of 4
Michael G. Rosenfeld, University of California, San Diego, USA
Enhancer, lncRNA and Architectural Codes of Regulated Transcriptional Programs Involved in Learning and Memory

Tuesday, February 24 | 5:00PM - 7:00PM
Molecular Mechanisms
Room: Anasazi Ballroom

Speaker 3 of 4
Paolo Sassone-Corsi, University of California, Irvine, USA
The Epigenetic Language of the Circadian Clock

Tuesday, February 24 | 5:00PM - 7:00PM
Molecular Mechanisms
Room: Anasazi Ballroom

Speaker 4 of 4
Alexander Nott, University of California, San Diego, USA
Short Talk: HDAC3 Mediates Epigenomic Regulation of Transcription Relevant to Autism-Associated Behaviors

Tuesday, February 24 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Zia Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, February 24 | 7:30PM - 10:00PM
Poster Session 2
Room: Zia Ballroom


Wednesday, February 25 | 7:00AM - 8:00AM
Breakfast
Room: Zia Ballroom


Wednesday, February 25 | 8:00AM - 11:00AM
The Role of Epigenetic Mechanisms in Brain Disorders and Rep
air

Room: Anasazi Ballroom

Speaker 1 of 6
* Antonella Riccio, University College London, UK

Wednesday, February 25 | 8:00AM - 11:00AM
The Role of Epigenetic Mechanisms in Brain Disorders and Rep
air

Room: Anasazi Ballroom

Speaker 2 of 6
Philip L. De Jager, Columbia University Medical Center, USA
An Integrative Approach to Deconstructing the Role of the Brain's Epigenome in Cognitive Aging

Wednesday, February 25 | 8:00AM - 11:00AM
The Role of Epigenetic Mechanisms in Brain Disorders and Rep
air

Room: Anasazi Ballroom

Speaker 3 of 6
Guo-li Ming, University of Pennsylvania, USA
Epigenetic Regulation in Regeneration and Repair after Injury

Wednesday, February 25 | 8:00AM - 11:00AM
The Role of Epigenetic Mechanisms in Brain Disorders and Rep
air

Room: Anasazi Ballroom

Speaker 4 of 6
Jenny Hsieh, University of Texas Southwestern Medical Center, USA
Transcriptional/Epigenetic Circuitry to Control Adult Hippocampal Neurogenesis

Wednesday, February 25 | 8:00AM - 11:00AM
The Role of Epigenetic Mechanisms in Brain Disorders and Rep
air

Room: Anasazi Ballroom

Speaker 5 of 6
Brooke H. Miller, University of Florida College of Medicine, USA
Short Talk: In vivo Analysis of the Effects of miR-132 on Epigenetic Factors Associated with Major Psychiatric Disorders

Wednesday, February 25 | 8:00AM - 11:00AM
The Role of Epigenetic Mechanisms in Brain Disorders and Rep
air

Room: Anasazi Ballroom

Speaker 6 of 6
Michael J. Ziller, Max Planck Institute of Psychiatry, Germany
Short Talk: Dissecting Neural Differentiation Regulatory Networks through Epigenetic Footprinting

Wednesday, February 25 | 9:20AM - 9:40AM
Coffee Break
Room: Zia Concourse


Wednesday, February 25 | 11:00AM - 5:00PM
On Own for Lunch


Wednesday, February 25 | 4:30PM - 5:00PM
Coffee Available
Room: Zia Concourse


Wednesday, February 25 | 5:00PM - 6:45PM
Epigenomes
Room: Anasazi Ballroom

Speaker 1 of 5
* Hongjun Song, University of Pennsylvania, USA

Wednesday, February 25 | 5:00PM - 6:45PM
Epigenomes
Room: Anasazi Ballroom

Speaker 2 of 5
* Li-Huei Tsai, Massachusetts Institute of Technology, USA

Wednesday, February 25 | 5:00PM - 6:45PM
Epigenomes
Room: Anasazi Ballroom

Speaker 3 of 5
Manolis Kellis, Massachusetts Institute of Technology, Broad Institute, USA
Conserved Epigenomic Signals in Mice and Humans Reveal Immune Basis of Alzheimer’s Disease

Wednesday, February 25 | 5:00PM - 6:45PM
Epigenomes
Room: Anasazi Ballroom

Speaker 4 of 5
Chuan He, University of Chicago, USA
Gene Expression Regulation through Reversible RNA and DNA Methylation

Wednesday, February 25 | 5:00PM - 6:45PM
Epigenomes
Room: Anasazi Ballroom

Speaker 5 of 5
Joseph R. Ecker, The Salk Institute for Biological Studies, USA
Epigenomic Signatures of Neuronal Cell Diversity in the Mammalian Brain

Wednesday, February 25 | 6:45PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Anasazi Ballroom


Wednesday, February 25 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Zia Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, February 25 | 8:00PM - 11:00PM
Entertainment
Room: Zia Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Wednesday, February 25 | 8:00PM - 11:00PM
Cash Bar
Room: Zia Ballroom


Thursday, February 26 | 10:25AM - 10:25AM
Departure


*Session Chair.