Web Desc
Gut Microbiota Modulation of Host Physiology: The Search for Mechanism
Organizer(s): Fredrik Bäckhed, Ruth E. Ley and Yasmine Belkaid
Date: March 01 - 06, 2015
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc., Cell Research, Nestlé Institute of Health Sciences, Novartis Institutes for BioMedical Research and Theravance Biopharma
Summary of Meeting:
Over the past decade, it has become evident that the gut microbiome is an important environmental factor that affects many physiologic processes, such as cell proliferation and differentiation, behavior, immune function and metabolism. Moreover, it may contribute to a wide variety of diseases, including cancer, inflammatory diseases, metabolic diseases and responses to pathogens. This meeting will emphasize mechanistic understandings of the relationship between microbiota and host physiology, rather than simply characterize microbiota in different disease states. Speakers will address not only bacteria in the gut, but also fungi and microbiome on the skin and in the lung. The goal of the meeting is to facilitate the understanding by which mechanisms of the microbiota modulate host physiologic processes and increase our understanding of how an altered microbiota contributes to health and disease in humans. In addition, the broad representation of speakers from diverse fields, such as microbiology, immunology, physiology and infectious disease, is likely to foster new collaborations.
Scholarship Deadline: November 3 2014
Discounted Abstract Deadline: November 3 2014
Abstract Deadline: December 2 2014
Discounted Registration Deadline: January 5 2015
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Boehringer Ingelheim Pharmaceuticals, Inc.Cell ResearchNestlé Institute of Health SciencesNovartis Institutes for BioMedical ResearchTheravance Biopharma
We gratefully acknowledge additional support for this conference from:
Mucosal Immunology Studies Team (MIST)Research Diets, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 1R13DK104614-01
Funding for this conference was made possible (in part) by 1 R13 DK104614-01 from NIDDK. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 01 | 4:00PM - 8:00PM
Arrival and Registration
Room: Longs Peak Foyer


Sunday, March 01 | 6:00PM - 8:00PM
Welcome Mixer
Room: Longs Peak Foyer
No registration fees are used to fund alcohol served at this function.

Monday, March 02 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Monday, March 02 | 8:00AM - 8:15AM
Welcome Remarks
Room: Longs/Grays Peak

Speaker 1 of 3
Fredrik Bäckhed, University of Gothenburg, Sweden

Monday, March 02 | 8:00AM - 8:15AM
Welcome Remarks
Room: Longs/Grays Peak

Speaker 2 of 3
Ruth E. Ley, Max Planck Institute for Developmental Biology, Germany

Monday, March 02 | 8:00AM - 8:15AM
Welcome Remarks
Room: Longs/Grays Peak

Speaker 3 of 3
Yasmine Belkaid, NIAID, National Institutes of Health, USA

Monday, March 02 | 8:15AM - 9:15AM
Keynote Address
Room: Grays Peak

Speaker 1 of 2
* Fredrik Bäckhed, University of Gothenburg, Sweden

Monday, March 02 | 8:15AM - 9:15AM
Keynote Address
Room: Grays Peak

Speaker 2 of 2
Herbert (Skip) W. Virgin, Vir Biotechnology, USA
Role of the Virome and Virome-Bacterial Microbiome Interactions in Immunity and Disease

Monday, March 02 | 9:15AM - 11:00AM
Gut Microbiota and Metabolic Disease
Room: Longs/Grays Peak

Speaker 1 of 4
* Patrice D. Cani, Université Catholique de Louvain, Belgium

Monday, March 02 | 9:15AM - 11:00AM
Gut Microbiota and Metabolic Disease
Room: Longs/Grays Peak

Speaker 2 of 4
Naoko Ohtani, Osaka City University Graduate School of Medicine, Japan
Obesity-Induced Gut Microbial Metabolite, DCA, Promotes Liver Cancer through Senescence Secretome

Monday, March 02 | 9:15AM - 11:00AM
Gut Microbiota and Metabolic Disease
Room: Longs/Grays Peak

Speaker 3 of 4
Fredrik Bäckhed, University of Gothenburg, Sweden
Gut Microbiota and Type 2 Diabetes

Monday, March 02 | 9:15AM - 11:00AM
Gut Microbiota and Metabolic Disease
Room: Longs/Grays Peak

Speaker 4 of 4
Megan T. Baldridge, Washington University School of Medicine, USA
Short Talk: Heritable Fecal IgA Levels Distinguish Extra-Chromosomal Phenotypic Variation

Monday, March 02 | 9:40AM - 10:00AM
Coffee Break
Room: Longs Peak Foyer


Monday, March 02 | 11:00AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Monday, March 02 | 11:00AM - 5:00PM
On Own for Lunch


Monday, March 02 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 1 of 9
* François Leulier, Institut de Génomique Fonctionnelle de Lyon, France

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 2 of 9
Jeremy J. Barr, Monash University, Australia
Bacteriophage as Mucosal Hunters

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 3 of 9
Juris A. Grasis, San Diego State University, USA
The Basal Metazoan Hydra as a Model for Host-Mucosa-Virome Interactions

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 4 of 9
Jennifer S. Hampton, University of Oregon, USA
Microbial Signaling Mechanisms Important for Pancreatic Beta Cell Expansion in Zebrafish

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 5 of 9
Siegfried Hapfelmeier, University of Bern, Switzerland
Next-Generation Models of Reversible Intestinal Colonization: Probing Mucosal Immunity

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 6 of 9
Carolyn Elya, University of California, Berkeley, USA
Employing Drosophila Melanogaster to Investigate How Gut Microbes affect Host Behavior

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 7 of 9
Kate P. Coyle, North Carolina State University, USA
Impact of Dietary Adaptation on Gastrointestinal Biology across Trophic Levels in Lake Malawi Cichlids

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 8 of 9
Claire Maynard, Durham University, UK
A Novel Mechanism to Improve Host Health by Intervening with Microbial Metabolism Discovered Using the C. elegans: E. coli Model

Monday, March 02 | 2:30PM - 4:30PM
Workshop 1: Novel Models to Study Host-Microbe Interactions
Room: Longs/Grays Peak

Speaker 9 of 9
Meng Wu, Washington University in St. Louis, USA
Identifying the Genetic Underpinnings of Niche in Human Gut Bacteria in Different Diet Contexts Using Multi-Taxon INSeq and Gnotobiotic Mice

Monday, March 02 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, March 02 | 5:00PM - 7:15PM
Microbiota-Diet Interactions
Room: Longs/Grays Peak

Speaker 1 of 5
Stanley L. Hazen, Cleveland Clinical Foundation, USA
Diet, Microbiota and Cardiometabolic Disease

Monday, March 02 | 5:00PM - 7:15PM
Microbiota-Diet Interactions
Room: Longs/Grays Peak

Speaker 2 of 5
Patrice D. Cani, Université Catholique de Louvain, Belgium
Gut Microbes, Host and Diet: Focus on a Novel Lipid Sensor

Monday, March 02 | 5:00PM - 7:15PM
Microbiota-Diet Interactions
Room: Longs/Grays Peak

Speaker 3 of 5
Amir Zarrinpar, University of California, San Diego and The Salk Institute, USA
Short Talk: Diet and Feeding Pattern Affect the Diurnal Dynamics of the Gut Microbiome

Monday, March 02 | 5:00PM - 7:15PM
Microbiota-Diet Interactions
Room: Longs/Grays Peak

Speaker 4 of 5
* Liping Zhao, Shanghai Jiao Tong University, China and Rutgers University, USA
Dysbiosis of Gut Microbiota as a Checkpoint for Obesity Development

Monday, March 02 | 5:00PM - 7:15PM
Microbiota-Diet Interactions
Room: Longs/Grays Peak

Speaker 5 of 5
Shirong Liu, Brigham and Women's Hospital/Harvard Medical School, USA
Short Talk: Identification of Fecal MicroRNAs and their Role in Regulating Gut Microbiota

Monday, March 02 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Monday, March 02 | 7:30PM - 10:00PM
Poster Session 1
Room: Shavano/Torreys


Tuesday, March 03 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 1 of 7
* Fiona M. Powrie, University of Oxford, UK

Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 2 of 7
Kenya Honda, Keio University School of Medicine, Japan
Regulation of T Cells by the Gut Microbiota

Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 3 of 7
Yasmine Belkaid, NIAID, National Institutes of Health, USA
Compartmentalized Control of Tissue Immunity by Commensals


Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 4 of 7
Dan R. Littman, HHMI/New York University School of Medicine, USA
Programming of T Cell Effector Functions by the Intestinal Microbiota

Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 5 of 7
Wendy S. Garrett, Harvard School of Public Health, USA
Short-Chain Fatty Acids and Regulatory T Cells

Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 6 of 7
Thaddeus S. Stappenbeck, Cleveland Clinic, USA
Short Talk: Regulation of Epithelial Turnover and Repair by Host-Virome Interactions

Tuesday, March 03 | 8:00AM - 11:15AM
Microbiota Induction of the Immune System I
Room: Longs/Grays Peak

Speaker 7 of 7
Thomas C. Fung, University of Pennsylvania, USA
Short Talk: A Lymphoid Tissue-Resident Commensal Bacterium Modulates Local Immune Responses in the Intestine

Tuesday, March 03 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 03 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Tuesday, March 03 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, March 03 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Tuesday, March 03 | 2:30PM - 4:30PM
Workshop 2: Cell Press Editors' Panel on How to Get Publishe
d
Room: Grays/Longs Peak


Tuesday, March 03 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 03 | 5:00PM - 7:00PM
Microbiota Induction of the Immune System II
Room: Longs/Grays Peak

Speaker 1 of 5
* Wendy S. Garrett, Harvard School of Public Health, USA

Tuesday, March 03 | 5:00PM - 7:00PM
Microbiota Induction of the Immune System II
Room: Longs/Grays Peak

Speaker 2 of 5
Gérard Eberl, Institut Pasteur, France
Regulation of RORgt+ T Cells by Microbiota and Diet

Tuesday, March 03 | 5:00PM - 7:00PM
Microbiota Induction of the Immune System II
Room: Longs/Grays Peak

Speaker 3 of 5
Fiona M. Powrie, University of Oxford, UK
Mucosal Inflammation: From IBD to Colon Cancer

Tuesday, March 03 | 5:00PM - 7:00PM
Microbiota Induction of the Immune System II
Room: Longs/Grays Peak

Speaker 4 of 5
Andrew J.S. Macpherson, University of Bern, Switzerland
Stratification of Intestinal Microbes

Tuesday, March 03 | 5:00PM - 7:00PM
Microbiota Induction of the Immune System II
Room: Longs/Grays Peak

Speaker 5 of 5
Duane R. Wesemann, Harvard Medical School, USA
Short Talk: Role of Microbes in B Cell Lymphopoiesis and Early Ig Repertoire Development

Tuesday, March 03 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Tuesday, March 03 | 7:30PM - 10:00PM
Poster Session 2
Room: Shavano/Torreys


Wednesday, March 04 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 1 of 8
* John F. Rawls, Duke University, USA

Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 2 of 8
David M. Underhill, Cedars-Sinai Medical Center, USA
Intestinal Fungi and their Role in Disease

Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 3 of 8
Julie A. Segre, National Institutes of Health, USA
Skin Microbiome: Bacterial, Fungal Diversity Across the Human Landscape

Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 4 of 8
François Leulier, Institut de Génomique Fonctionnelle de Lyon, France
Host/Lactobacilli Mutualism: 'Learning on the Fly'

Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 5 of 8
Marie-Claire Arrieta, University of Calgary, Canada
Short Talk: Early-Infancy Microbial and Metabolic Alterations Impact Risk of Asthma

Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 6 of 8
Anisa S. Ismail, Princeton University, USA
Short Talk: Identification of a Host-Produced Molecule that Mimics Autoinducer-2
(AI-2) Activity


Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 7 of 8
Elisabeth Kernbauer, New York University School of Medicine, USA
Short Talk: An Enteric Viral Infection Can Functionally Replace the Beneficial Cues Provided by Commensal Bacteria

Wednesday, March 04 | 8:00AM - 11:15AM
Emerging Areas of Host-Microbiome Interactions
Room: Longs/Grays Peak

Speaker 8 of 8
Jean-Marc Chatel, Micalis Institute, France
Short Talk: Identification of an Anti-Inflammatory Protein from Faecalibacterium prausnitzii, a Commensal Bacterium Deficient in Crohn's Disease

Wednesday, March 04 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, March 04 | 11:15AM - 1:00PM
Poster Setup
Room: Shavano/Torreys


Wednesday, March 04 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, March 04 | 1:00PM - 10:00PM
Poster Viewing
Room: Shavano/Torreys


Wednesday, March 04 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, March 04 | 5:00PM - 7:00PM
Mucus-Microbiota Interactions
Room: Longs/Grays Peak

Speaker 1 of 5
* Justin L. Sonnenburg, Stanford University, USA

Wednesday, March 04 | 5:00PM - 7:00PM
Mucus-Microbiota Interactions
Room: Longs/Grays Peak

Speaker 2 of 5
Gunnar C. Hansson, University of Gothenburg, Sweden
The Mucus Layer as First Line of Defense

Wednesday, March 04 | 5:00PM - 7:00PM
Mucus-Microbiota Interactions
Room: Longs/Grays Peak

Speaker 3 of 5
Lora V. Hooper, University of Texas Southwestern Medical Center, USA
Circadian Regulation of Intestinal Host-Microbe Interactions

Wednesday, March 04 | 5:00PM - 7:00PM
Mucus-Microbiota Interactions
Room: Longs/Grays Peak

Speaker 4 of 5
Eric C. Martens, University of Michigan Medical School, USA
Think Globally, Act Locally: Regulated Deployment of Diet and Mucus Polysaccharide Degradation by Gut Bacteria

Wednesday, March 04 | 5:00PM - 7:00PM
Mucus-Microbiota Interactions
Room: Longs/Grays Peak

Speaker 5 of 5
Hiutung Chu, California Institute of Technology, USA
Short Talk: Microbiota-Induced Autophagy Promotes Mucosal Tolerance

Wednesday, March 04 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Wednesday, March 04 | 7:30PM - 10:00PM
Poster Session 3
Room: Shavano/Torreys


Thursday, March 05 | 7:00AM - 8:00AM
Breakfast
Room: Shavano/Torreys


Thursday, March 05 | 8:00AM - 11:00AM
Gut Microbiota in Relation to Infectious Diseases
Room: Longs/Grays Peak

Speaker 1 of 6
* Lora V. Hooper, University of Texas Southwestern Medical Center, USA

Thursday, March 05 | 8:00AM - 11:00AM
Gut Microbiota in Relation to Infectious Diseases
Room: Longs/Grays Peak

Speaker 2 of 6
Wolf-Dietrich Hardt, ETH Zürich, Switzerland
Salmonella Diarrhea Results from Multiple Pathogen-Microbiota-Host Interactions

Thursday, March 05 | 8:00AM - 11:00AM
Gut Microbiota in Relation to Infectious Diseases
Room: Longs/Grays Peak

Speaker 3 of 6
Justin L. Sonnenburg, Stanford University, USA
Interactions between the Microbiota and Pathogenic Bacteria

Thursday, March 05 | 8:00AM - 11:00AM
Gut Microbiota in Relation to Infectious Diseases
Room: Longs/Grays Peak

Speaker 4 of 6
Gabriel Nuñez, University of Michigan, USA
Control of Enteric Pathogens by Host Immunity and the Microbiota

Thursday, March 05 | 8:00AM - 11:00AM
Gut Microbiota in Relation to Infectious Diseases
Room: Longs/Grays Peak

Speaker 5 of 6
Eric G. Pamer, University of Chicago, USA
Microbiota-Mediated Defense Against Intestinal Infection

Thursday, March 05 | 8:00AM - 11:00AM
Gut Microbiota in Relation to Infectious Diseases
Room: Longs/Grays Peak

Speaker 6 of 6
Mario M. Zaiss, École Polytechnique Fédérale de Lausanne, EPFL, Switzerland
Short Talk: Intestinal Helminths Modulate Allergic Inflammation Indirectly by Altering Bacterial Metabolism

Thursday, March 05 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, March 05 | 11:00AM - 5:00PM
On Own for Lunch


Thursday, March 05 | 2:30PM - 4:30PM
Panel: The Integrative Human Microbiome Project (iHMP): Dyna
mic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease
Room: Longs/Grays Peaks
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 1 of 4
Robert W. Karp, National Institutes of Health, USA

Thursday, March 05 | 2:30PM - 4:30PM
Panel: The Integrative Human Microbiome Project (iHMP): Dyna
mic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease
Room: Longs/Grays Peaks
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 2 of 4
Gregory A. Buck, Virginia Commonwealth University, USA

Thursday, March 05 | 2:30PM - 4:30PM
Panel: The Integrative Human Microbiome Project (iHMP): Dyna
mic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease
Room: Longs/Grays Peaks
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 3 of 4
Curtis Huttenhower, Harvard School of Public Health, USA

Thursday, March 05 | 2:30PM - 4:30PM
Panel: The Integrative Human Microbiome Project (iHMP): Dyna
mic Analysis of Microbiome-Host Omics Profiles during Periods of Human Health and Disease
Room: Longs/Grays Peaks
The Integrative Human Microbiome Project (iHMP) is the second phase of the National Institute of Health (NIH) Common Fund's Human Microbiome Project (HMP) program. The mission of the overall HMP is to generate resources to permit comprehensive characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease. In this phase of the program, the iHMP is creating integrated longitudinal datasets of biological properties from both the microbiome and host from three different cohort studies of microbiome-associated conditions using multiple 'omics' technologies. Tools, datasets and other resources from the first phase of the project are available at the HMP DACC. During this session, we will provide an overview of the data and resources freely available to the research community as derived from the three iHMP projects: 1) the Multi-Omic Microbiome Study: Pregnancy Initiative (MOMS-PI) at Virginia Commonwealth University, 2) the Inflammatory Bowel Disease Multi'omic Data (IBDMDB) resource from the Broad Institute and a nation-wide research tam, and 3) Integrated Personal 'Omics Profiling (IPOP) from Stanford University and the Jackson Laboratory for Genomic Medicine. For more information or to get involved with the iHMP, please see http://hmp2.org.
Speaker 4 of 4
Wenyu Zhou, Stanford University, USA

Thursday, March 05 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, March 05 | 5:00PM - 6:45PM
Microbiome Interactions with Host Genetics: Future Insights
to New Mechanisms

Room: Longs/Grays Peak

Speaker 1 of 4
* Gabriel Nuñez, University of Michigan, USA

Thursday, March 05 | 5:00PM - 6:45PM
Microbiome Interactions with Host Genetics: Future Insights
to New Mechanisms

Room: Longs/Grays Peak

Speaker 2 of 4
Jens Walter, APC Microbiome Ireland. University College Cork, Ireland
Bacterial Genetic Factors that Determine Host-Specific Colonization: The Case of Lactobacilli

Thursday, March 05 | 5:00PM - 6:45PM
Microbiome Interactions with Host Genetics: Future Insights
to New Mechanisms

Room: Longs/Grays Peak

Speaker 3 of 4
John F. Rawls, Duke University, USA
Microbial Regulation of Intestinal Lipid Metabolism and Gene Expression

Thursday, March 05 | 5:00PM - 6:45PM
Microbiome Interactions with Host Genetics: Future Insights
to New Mechanisms

Room: Longs/Grays Peak

Speaker 4 of 4
Ruth E. Ley, Max Planck Institute for Developmental Biology, Germany
Host Genetics Analyses of Microbiome Composition: Gene Screens for Identifying Novel Mechanisms

Thursday, March 05 | 6:45PM - 7:15PM
Meeting Wrap-Up
Room: Longs/Grays Peak
Organizers will discuss outcomes, future directions and present their choice of poster award.

Thursday, March 05 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Shavano/Torreys
No registration fees are used to fund alcohol served at this function.

Thursday, March 05 | 8:00PM - 11:00PM
Entertainment
Room: Shavano/Torreys
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, March 05 | 8:00PM - 11:00PM
Cash Bar
Room: Shavano/Torreys


Friday, March 06 | 10:25AM - 10:25AM
Departure


*Session Chair.