Web Desc
Hypoxia: From Basic Mechanisms to Therapeutics
Organizer(s): Cormac T. Taylor, M. Celeste Simon, Sean P. Colgan and Roland H. Wenger
Date: May 12 - 17, 2015
Location: Royal Dublin Society, Dublin 4, Ireland
Organized in Collaboration with Science Foundation Ireland. Sponsored by Boehringer Ingelheim Pharmaceuticals, Inc.
For important information on the coronavirus, please click here
Summary of Meeting:
Tissue hypoxia occurs in a range of physiologic and pathophysiologic states. Consequently, the cellular response to hypoxia has important implications for both health and for diseases including (but not limited to) cancer, ischemia and chronic inflammation. Recently, the discovery and elucidation of specific hypoxia-inducible pathways has raised the possibility of developing new strategies for therapeutic benefit based on targeting hypoxia-sensitive pathways. The aim of this meeting is to disseminate up to date information on basic mechanisms of the cellular hypoxic response, discuss the impact of this response for health and disease and highlight the potential for developing new therapeutics based on our understanding of the pathways involved. It is anticipated that outcomes of this meeting will include the dissemination of new scientific knowledge, the discussion of new methodologies, the education of graduate students and fellows in the state-of-the-art and promoting new collaborations between clinicians, basic researchers and industrial partners. The Keystone Symposia Hypoxia meeting is widely accepted as the world’s leading conference addressing the topic and is a key date on the calendar for all researchers interested in this topic. We will bring together academic, clinical and industrial researchers to drive synergy through collaboration in developing the translational potential of targeting the HIF pathway for therapeutic benefit. This meeting will be held in conjunction with the European HypoxiaNET consortium.
Scholarship Deadline: January 13 2015
Discounted Abstract Deadline: January 13 2015
Abstract Deadline: February 12 2015
Discounted Registration Deadline: March 12 2015
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
BioLegend, Inc.Boehringer Ingelheim Pharmaceuticals, Inc.Science Foundation Ireland
We gratefully acknowledge additional support for this conference from:
Baker RuskinnBMG LABTECH Ltd.Coy Laboratory Products Inc.Don Whitley Scientific LimitedDove Medical Press LtdFáilte IrelandFibroGen IncorporatedLuxcel BioSciences Ltd.
Merck Serono/Merck
Oxford Optronix Ltd.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, May 12 | 4:00PM - 8:00PM
Arrival and Registration
Room: Hall 4 (Industries Hall)


Tuesday, May 12 | 6:00PM - 8:00PM
Welcome Mixer
Room: Hall 4 (Industries Hall)
No registration fees are used to fund alcohol served at this function.

Wednesday, May 13 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Wednesday, May 13 | 7:30AM - 8:00AM
Poster Setup
Room: Hall 4 (Industries Hall)


Wednesday, May 13 | 8:00AM - 5:00PM
Poster Viewing
Room: Hall 4 (Industries Hall)


Wednesday, May 13 | 8:00AM - 9:00AM
Keynote Address
Room: Hall 1 (Main Hall)

Speaker 1 of 2
* Cormac Taylor, University College Dublin, Ireland

Wednesday, May 13 | 8:00AM - 9:00AM
Keynote Address
Room: Hall 1 (Main Hall)

Speaker 2 of 2
Peter F. Carmeliet, University of Leuven, VIB, Belgium
Oxygen and Nutrient Metabolism in Neurovascular Processes in Health and Disease

Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 1 of 7
* Roland H. Wenger, University of Zürich, Switzerland

Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 2 of 7
Cormac Taylor, University College Dublin, Ireland
Regulation of Inflammatory Pathways by Hypoxia



Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 3 of 7
Sean P. Colgan, University of Colorado Denver, USA
HIF as a Target in Mucosal Inflammation

Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 4 of 7
Randall S. Johnson, University of Cambridge, UK
HIF and Vascular Disease

Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 5 of 7
Judith Sluimer, Maastricht University, Netherlands
Short Talk: Myeloid PHD2 Deficiency Impairs Collagen Degradation Enhancing Murine Atherosclerotic Plaque Stability

Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 6 of 7
Claudia Gerri, Max Planck Institute for Heart and Lung Research, Germany
Short Talk: Role of the HIF Pathway in Cardiovascular System Development in Zebrafish

Wednesday, May 13 | 9:00AM - 12:15PM
Hypoxia and Disease-Specific Targets
Room: Hall 1 (Main Hall)

Speaker 7 of 7
M. Celeste Simon, University of Pennsylvania, USA
Hypoxia, Lipids and Cancer: Surviving the Harsh Tumor Microenvironment

Wednesday, May 13 | 9:40AM - 10:00AM
Coffee Break
Room: Hall 4 (Industries Hall)


Wednesday, May 13 | 12:15PM - 1:00PM
Lunch
Room: Hall 4 (Industries Hall)


Wednesday, May 13 | 12:30PM - 2:30PM
Poster Session 1
Room: Hall 4 (Industries Hall)


Wednesday, May 13 | 2:30PM - 4:30PM
HypoxiaNET Workshop 1: Targeting Hypoxia-Sensitive Pathways
Room: Hall 1 (Main Hall)

Speaker 1 of 5
* Christopher J. Schofield, University of Oxford, UK
Perspectives on Iron Oxygenases as Therapeutic Targets

Wednesday, May 13 | 2:30PM - 4:30PM
HypoxiaNET Workshop 1: Targeting Hypoxia-Sensitive Pathways
Room: Hall 1 (Main Hall)

Speaker 2 of 5
Gail Walkinshaw, FibroGen, USA
Therapeutic Applications for HIF Prolyl Hydroxylase Inhibitors

Wednesday, May 13 | 2:30PM - 4:30PM
HypoxiaNET Workshop 1: Targeting Hypoxia-Sensitive Pathways
Room: Hall 1 (Main Hall)

Speaker 3 of 5
Laura Demopoulos, GlaxoSmithKline, USA
The Promise of HIF Prolyl Hydroxylase Inhibitors: Clinical Applications

Wednesday, May 13 | 2:30PM - 4:30PM
HypoxiaNET Workshop 1: Targeting Hypoxia-Sensitive Pathways
Room: Hall 1 (Main Hall)

Speaker 4 of 5
Ingo Flamme, Bayer Pharma AG, Germany
Mimicking Hypoxia to Treat Anemia:
HIF-Stabilizer BAY 85-3934 (Molidustat)


Wednesday, May 13 | 2:30PM - 4:30PM
HypoxiaNET Workshop 1: Targeting Hypoxia-Sensitive Pathways
Room: Hall 1 (Main Hall)

Speaker 5 of 5
Ivan Coulter, Sigmoid Pharma, Ireland
SmPill® Gastrointestinal Targeted Hydroxylase Inhibitors: HIF Where it Hurts

Wednesday, May 13 | 4:30PM - 5:00PM
Coffee Available
Room: Hall 4 (Industries Hall)


Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 1 of 7
* Margaret Ashcroft, University of Cambridge, UK

Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 2 of 7
Julie-Aurore Losman, Dana-Farber Cancer Institute, USA
Targeting Leukemia Cell Metabolism: Insights Gained from Studies of Mutant IDH

Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 3 of 7
Till Acker, University of Giessen, Germany
PHDs and Hallmarks of Cancer

Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 4 of 7
Amato J. Giaccia, Stanford University, USA
Suppression of PGC-1alpha Links the Clear Cell Phenotype with Tumor Growth in Renal Cell Carcinoma

Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 5 of 7
Emin Maltepe, University of California, San Francisco, USA
Short Talk: HIGD1A Regulation of Tumor Metabolism and Growth

Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 6 of 7
Cormac Taylor, University College Dublin, Ireland
Introduction to Salvador Moncada

Wednesday, May 13 | 5:00PM - 7:30PM
Hypoxia and Cancer
Room: Hall 1 (Main Hall)

Speaker 7 of 7
Salvador Moncada, University of Manchester, UK
Pursuing the Biology of O2/NO2 Interactions: Where Are We Now?

Wednesday, May 13 | 7:30PM - 7:30PM
On Own for Dinner


Thursday, May 14 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Thursday, May 14 | 7:30AM - 8:00AM
Poster Setup
Room: Hall 4 (Industries Hall)


Thursday, May 14 | 8:00AM - 5:00PM
Poster Viewing
Room: Hall 4 (Industries Hall)


Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 1 of 7
* Drorit Neumann, Tel-Aviv University, Israel

Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 2 of 7
Richard K. Bruick, University of Texas Southwestern Medical Center, USA
Administration of a Small Molecule HIF-2 Inhibitor Reduces Iron Overload in a Mouse Model of Hemochromatosis

Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 3 of 7
Jacques Pouysségur, University of Nice, France
Hypoxic Microenvironment and Control of Tumor Metabolism

Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 4 of 7
Gregg L. Semenza, Johns Hopkins University School of Medicine, USA
Hypoxia-Inducible Factors Support the Breast Cancer Stem Cell Phenotype

Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 5 of 7
Frank S. Lee, University of Pennsylvania School of Medicine, USA
Oxygen Sensing by PHD2

Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 6 of 7
Werner J. Kovacs, ETH Zurich, Switzerland
Short Talk: Hif-2alpha Promotes Degradation of Mammalian Peroxisomes by Selective Autophagy

Thursday, May 14 | 8:00AM - 11:15AM
HIF-Dependent Pathways
Room: Hall 1 (Main Hall)

Speaker 7 of 7
Cunming Duan, University of Michigan, USA
Short Talk: Dissecting Oxygen-Dependent and -Independent Actions of Hypoxia-Inducible Factor 3 Using CRISPR/Cas9-Based Gene Editing

Thursday, May 14 | 9:20AM - 9:40AM
Coffee Break
Room: Hall 4 (Industries Hall)


Thursday, May 14 | 11:15AM - 12:30PM
Lunch
Room: Hall 4 (Industries Hall)


Thursday, May 14 | 12:30PM - 2:30PM
Poster Session 2
Room: Hall 4 (Industries Hall)


Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 1 of 8
* Chris W. Pugh, University of Oxford, UK

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 2 of 8
Eoin Cummins, University College Dublin, Ireland
Oxygen and Carbon Dioxide Cross-Talk in the HIF Pathway

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 3 of 8
Louise E. Glover, University of Colorado, USA
Metabolic Regulation of Epithelial Autophagy in Mucosal Inflammation

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 4 of 8
David R. Mole, University of Oxford, UK
Pangenomic Studies of the HIF Transcriptional Response

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 5 of 8
Julián Aragonés Lopez, Research Institute Princesa, Spain
Role of HIF2alpha in Airway Response to Oxygen Fluctuations

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 6 of 8
Martin Schneider, University of Heidelberg, Germany
PHD-Inhibition in Surgery for Metastatic Colorectal Cancer

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 7 of 8
Edurne Berra, CIC bioGUNE, Spain
New Insights into HIF Homeostasis

Thursday, May 14 | 2:30PM - 4:30PM
HypoxiaNET Workshop 2
Room: Hall 1 (Main Hall)

Speaker 8 of 8
Norbert Weissmann, Justus-Liebig-University Giessen, Germany
Identification of Mechanisms Driving Hypoxia-Induced Pulmonary Hypertension and its Reversal

Thursday, May 14 | 4:30PM - 5:00PM
Coffee Available
Room: Hall 4 (Industries Hall)


Thursday, May 14 | 5:00PM - 7:00PM
HIF-Independent Pathways
Room: Hall 1 (Main Hall)

Speaker 1 of 5
* Edwin R. Chilvers, Cambridge University, UK

Thursday, May 14 | 5:00PM - 7:00PM
HIF-Independent Pathways
Room: Hall 1 (Main Hall)

Speaker 2 of 5
Navdeep S. Chandel, Northwestern University, USA
Mitochondria Regulate Hypoxic Signal Transduction

Thursday, May 14 | 5:00PM - 7:00PM
HIF-Independent Pathways
Room: Hall 1 (Main Hall)

Speaker 3 of 5
Joachim Fandrey, University Duisburg-Essen, Germany
HIF-Complexes

Thursday, May 14 | 5:00PM - 7:00PM
HIF-Independent Pathways
Room: Hall 1 (Main Hall)

Speaker 4 of 5
Moira K. Whyte, University of Edinburgh, Queen's Medical Research Institute, UK
Regulation of Neutrophil Energetics by Hypoxia and the HIF/Hydroxylase Pathway: Consequences for Innate Immune Responses

Thursday, May 14 | 5:00PM - 7:00PM
HIF-Independent Pathways
Room: Hall 1 (Main Hall)

Speaker 5 of 5
Safia Thaminy, ETH Zürich, Switzerland
Short Talk: A Systems-Based Approach to Understand the Mechanisms of Cancer Progression Under Hypoxia

Thursday, May 14 | 7:00PM - 7:00PM
On Own for Dinner


Friday, May 15 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Friday, May 15 | 7:30AM - 8:00AM
Poster Setup
Room: Hall 4 (Industries Hall)


Friday, May 15 | 8:00AM - 5:00PM
Poster Viewing
Room: Hall 4 (Industries Hall)


Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 1 of 7
* L. Eric Huang, University of Utah, USA

Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 2 of 7
Peter J. Ratcliffe, University of Oxford, UK
Genomic Analysis of the Response to Hypoxia

Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 3 of 7
Sonia Rocha, University of Liverpool, UK
Role of Prolyl-Hydroxylases in the Control of the Cell Cycle and Related Processes

Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 4 of 7
Johanna Myllyharju, University of Oulu, Finland
Prolyl 4-Hydroxylases and the Hypoxic Response

Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 5 of 7
Daniel J. Peet, University of Adelaide, Australia
Hypoxic Signaling by FIH-Mediated Asparaginyl Hydroxylation

Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 6 of 7
Mathew Coleman, University of Birmingham, UK
Short Talk: Characterization of FIH-Related Protein Hydroxylases

Friday, May 15 | 8:00AM - 11:15AM
Hydroxylases and the Hypoxia Response
Room: Hall 1 (Main Hall)

Speaker 7 of 7
Qing Zhang, UT Southwestern Medical Center, USA
Short Talk: Control of NRF-PGC1alpha Complex and Mitochondrial Function by EglN2 in Breast Cancer

Friday, May 15 | 9:20AM - 9:40AM
Coffee Break
Room: Hall 4 (Industries Hall)


Friday, May 15 | 11:15AM - 12:30PM
Lunch
Room: Hall 4 (Industries Hall)


Friday, May 15 | 12:30PM - 2:30PM
Poster Session 3
Room: Hall 4 (Industries Hall)


Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 1 of 8
* Patrick Henry Maxwell, University of Cambridge, UK
Will HIF Hydroxylase Inhibitors Be Useful Medicines?

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 2 of 8
Agnes Görlach, German Heart Center Munich, TU Munich, Germany
MAP Kinase Signaling and the Response to Hypoxia

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 3 of 8
Ben Wielockx, Technical University of Dresden, Germany
The PHD2-HIF2alpha-EPO Axis: A Central Regulator of Erythropoiesis and Beyond

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 4 of 8
Peppi Koivunen, University of Oulu, Finland
HIF Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 5 of 8
Eric L. Campbell, UK
Epithelial-Derived HIF-Dependent Factors Coordinate Resolution of Colitis

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 6 of 8
Thomas Kietzmann, University of Oulu, Finland
Fbw7 and USP28-Dependent Degradation of HIFs: Old Features and Novel Aspects

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 7 of 8
Sarah R. Walmsley, University of Edinburgh, Queen's Medical Research Institute, UK
How Hypoxia and Hypoxic Pre-Conditioning Modify Outcomes of Bacterial Infection

Friday, May 15 | 2:30PM - 4:30PM
HypoxiaNET Workshop 3
Room: Hall 1 (Main Hall)

Speaker 8 of 8
Silvia Pastorekova, Biomedical Research Center, Slovak Academy of Sciences, Slovakia
Soluble Ectodomain of the Hypoxia-Induced Carbonic Anhydrase IX: More than
a Circulating Cancer Biomarker


Friday, May 15 | 4:30PM - 5:00PM
Coffee Available
Room: Hall 4 (Industries Hall)


Friday, May 15 | 5:00PM - 7:15PM
Hypoxia and Genetics
Room: Hall 1 (Main Hall)

Speaker 1 of 6
* Peter A. Robbins, University of Oxford, UK

Friday, May 15 | 5:00PM - 7:15PM
Hypoxia and Genetics
Room: Hall 1 (Main Hall)

Speaker 2 of 6
Roland H. Wenger, University of Zürich, Switzerland
Regulation of the EPO Gene

Friday, May 15 | 5:00PM - 7:15PM
Hypoxia and Genetics
Room: Hall 1 (Main Hall)

Speaker 3 of 6
Lorenz Poellinger, Karolinska Institutet, Sweden
Epigenetic Mechanisms Regulating the Hypoxic Response

Friday, May 15 | 5:00PM - 7:15PM
Hypoxia and Genetics
Room: Hall 1 (Main Hall)

Speaker 4 of 6
Josef Prchal, University of Utah, USA
HIF as a Target in Erythropoiesis

Friday, May 15 | 5:00PM - 7:15PM
Hypoxia and Genetics
Room: Hall 1 (Main Hall)

Speaker 5 of 6
Ian Frew, University of Zürich, Switzerland
Short Talk: Hif1a and Hif2a Are Both Required for the Formation of Vhl-Deficient Renal Cysts and Tumours

Friday, May 15 | 5:00PM - 7:15PM
Hypoxia and Genetics
Room: Hall 1 (Main Hall)

Speaker 6 of 6
Michail Sitkovsky, Northeastern University, USA
Short Talk: Conceptually Novel “Anti-A2A-Adenosinergic” Molecular Motivation to Oxygenate Hypoxic Tumors in Combination with Immunotherapies of Cancer

Friday, May 15 | 7:15PM - 7:15PM
On Own for Dinner


Saturday, May 16 | 7:00AM - 8:00AM
Breakfast
Room: Individual Hotel


Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 1 of 8
* Paul McLoughlin, University College Dublin, Ireland

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 2 of 8
Max Gassmann, University of Zürich, Switzerland
Erythropoietin through Evolution, a Speculative View

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 3 of 8
Dörthe M. Katschinski, Georg August University, Germany
Impact of Hypoxia and the Prolyl-4-Hydroxylase Domain Enzymes on Endocytosis and Cell Migration

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 4 of 8
José López-Barneó, University of Seville, Spain
Carotid Body Oxygen Sensing

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 5 of 8
Volker H. Haase, Vanderbilt University, USA
Mouse Models of Disrupted Oxygen Sensing

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 6 of 8
Nanduri R. Prabhakar, University of Chicago, USA
Interplay between Gas Messengers: A Key Step in Carotid Body O2 Sensing

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 7 of 8
Paul Moynagh, National University of Ireland, Maynooth, Ireland
Short Talk: The E3 Ubiquitin Ligase Pellino3 Acts as a Regulator of HIF-1alpha and IL-1beta Expression in Insulin Resistance

Saturday, May 16 | 8:00AM - 11:45AM
Physiology of Hypoxic Pathways
Room: Hall 1 (Main Hall)

Speaker 8 of 8
Elizabeth J. Campbell, University of Otago, Christchurch, New Zealand
Short Talk: Using Physiological and Pharmacological Ascorbate to Manipulate HIF-1 Activity in Gulo-/- Mice

Saturday, May 16 | 9:20AM - 9:40AM
Coffee Break
Room: Hall 4 (Industries Hall)


Saturday, May 16 | 11:45AM - 4:30PM
On Own for Lunch


Saturday, May 16 | 4:30PM - 5:00PM
Coffee Available
Room: Hall 4 (Industries Hall)


Saturday, May 16 | 5:00PM - 7:00PM
Hypoxia and Inflammation
Room: Hall 1 (Main Hall)

Speaker 1 of 5
* Thorsten Cramer, RWTH Aachen University, Germany

Saturday, May 16 | 5:00PM - 7:00PM
Hypoxia and Inflammation
Room: Hall 1 (Main Hall)

Speaker 2 of 5
Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Metabolic Reprogramming in Innate Immunity and Inflammation - A Critical Role for HIF-1alpha

Saturday, May 16 | 5:00PM - 7:00PM
Hypoxia and Inflammation
Room: Hall 1 (Main Hall)

Speaker 3 of 5
Massimiliano Mazzone, KU Leuven – VIB, Belgium
Influence on Vessel Shape of Macrophage Metabolism in the Tumor Hypoxic Niche

Saturday, May 16 | 5:00PM - 7:00PM
Hypoxia and Inflammation
Room: Hall 1 (Main Hall)

Speaker 4 of 5
Yatrik Shah, University of Michigan, USA
Intestinal HIF2alpha Signaling: A Critical Regulator of Intestinal Inflammation and Colon Cancer

Saturday, May 16 | 5:00PM - 7:00PM
Hypoxia and Inflammation
Room: Hall 1 (Main Hall)

Speaker 5 of 5
Christian Stockmann, University of Zurich, Switzerland
Short Talk: The Hypoxic Response in Natural Killer Cells: Impact on Cancer Immune Surveillance and Tumor Angiogenesis

Saturday, May 16 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Hall 1 (Main Hall)


Saturday, May 16 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Hall 4 (Industries Hall)
No registration fees are used to fund alcohol served at this function.

Saturday, May 16 | 8:00PM - 11:00PM
Entertainment
Room: Hall 4 (Industries Hall)
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Saturday, May 16 | 8:00PM - 11:00PM
Cash Bar
Room: Hall 4 (Industries Hall)


Sunday, May 17 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.