Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
Tuberculosis: Science Aimed at Ending the Epidemic (2021EK10)
Tuberculosis: Immunity and Immune Evasion (2020A2)
Tuberculosis: Mechanisms, Pathogenesis and Treatment (2019A3)
Tuberculosis: Translating Scientific Findings for Clinical and Public Health Impact (2018X7)
New Developments in Our Basic Understanding of Tuberculosis (2017A5)
Tuberculosis Co-Morbidities and Immunopathogenesis (2016B6)

Web Desc
Host Response in Tuberculosis joint with Granulomas in Infectious and Non-Infectious Diseases Organizer(s): JoAnne L. Flynn and Willem A. Hanekom Date: January 22 - 27, 2015 Location: Santa Fe Community Convention Center, Santa Fe, NM, USA Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation Summary of Meeting: Tuberculosis remains a major cause of morbidity and mortality globally. Control of the epidemic is hampered by limited understanding of basic processes underlying disease and protection. This symposium will focus on basic science in humans; major themes will include immune processes that have emerged as important for pathogenesis or protection. Translation of basic science advances into novel strategies to prevent and manage human tuberculosis will also be discussed. While preclinical progress will be addressed throughout the meeting, emphasis of direct relevance to human tuberculosis will be part of each presentation. The meeting will be held jointly with a Keystone Symposia meeting on “Granulomas in Infectious and Non-Infectious Diseases.” Granulomas are a pathologic hallmark of tuberculosis, so the pairing of these two meetings will enhance opportunities for interdisciplinary interactions and for learning about other granulomatous systems and providing insights into how this knowledge may be applied to our understanding of tuberculosis. The specific aims for this meeting are to: 1) Gather scientists interested in basic pathogenesis and immunologic responses in tuberculosis to present and discuss cutting-edge tuberculosis research; 2) Integrate basic and clinical research findings with a view to improving treatment and prevention of disease in humans; 3) Provide mentoring opportunities for junior scientists with senior scientists interested in tuberculosis research; and 4) Focus on gaps in knowledge about the events in natural infection, as well as vulnerability points for intervening in the infection process. Global Health Travel Award Deadline: August 19 2014 Scholarship Deadline: September 29 2014 Discounted Abstract Deadline: September 29 2014 Abstract Deadline: October 22 2014 Discounted Registration Deadline: November 20 2014 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: $2,500 - $9,999 We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI114099-01 Funding for this conference was made possible (in part) by 1 R13 AI 114099 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Host Response in Tuberculosis

joint with Granulomas in Infectious and Non-Infectious Diseases

Organizer(s): JoAnne L. Flynn and Willem A. Hanekom

Date: January 22 - 27, 2015
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA

Part of the Keystone Symposia Global Health Series, supported by the Bill & Melinda Gates Foundation

Summary of Meeting:

Tuberculosis remains a major cause of morbidity and mortality globally. Control of the epidemic is hampered by limited understanding of basic processes underlying disease and protection. This symposium will focus on basic science in humans; major themes will include immune processes that have emerged as important for pathogenesis or protection. Translation of basic science advances into novel strategies to prevent and manage human tuberculosis will also be discussed. While preclinical progress will be addressed throughout the meeting, emphasis of direct relevance to human tuberculosis will be part of each presentation. The meeting will be held jointly with a Keystone Symposia meeting on “Granulomas in Infectious and Non-Infectious Diseases.” Granulomas are a pathologic hallmark of tuberculosis, so the pairing of these two meetings will enhance opportunities for interdisciplinary interactions and for learning about other granulomatous systems and providing insights into how this knowledge may be applied to our understanding of tuberculosis. The specific aims for this meeting are to: 1) Gather scientists interested in basic pathogenesis and immunologic responses in tuberculosis to present and discuss cutting-edge tuberculosis research; 2) Integrate basic and clinical research findings with a view to improving treatment and prevention of disease in humans; 3) Provide mentoring opportunities for junior scientists with senior scientists interested in tuberculosis research; and 4) Focus on gaps in knowledge about the events in natural infection, as well as vulnerability points for intervening in the infection process.

Global Health Travel Award Deadline: August 19 2014

Scholarship Deadline: September 29 2014

Discounted Abstract Deadline: September 29 2014

Abstract Deadline: October 22 2014

Discounted Registration Deadline: November 20 2014

Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:

$2,500 - $9,999

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI114099-01
Funding for this conference was made possible (in part) by 1 R13 AI 114099 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations

Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program


Thursday, January 22 \| 4:00PM - 8:00PM Arrival and Registration Room: Sweeney Ballroom Foyer
Thursday, January 22 \| 6:00PM - 8:00PM Welcome Mixer Room: Sweeney F No registration fees are used to fund alcohol served at this function.
Friday, January 23 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 7:30AM - 8:00AM Poster Setup Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 8:00AM - 5:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 8:00AM - 9:00AM Keynote Address Room: Sweeney Ballroom A-D Setting the stage for addressing tuberculosis from a human perspective--from basic to clinical research. Speaker 1 of 2 * JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA
Friday, January 23 \| 8:00AM - 9:00AM Keynote Address Room: Sweeney Ballroom A-D Setting the stage for addressing tuberculosis from a human perspective--from basic to clinical research. Speaker 2 of 2 Clifton E. Barry III, NIAID, National Institutes of Health, USA Human Tuberculosis: The Movie
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 1 of 5 * Alan Sher, NIAID, National Institutes of Health, USA
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 2 of 5 David M. Lewinsohn, Oregon Health & Science University, USA MAITs and Protection Against TB
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 3 of 5 Henry Charles Mwandumba, Liverpool School of Tropical Medicine, UK TB/HIV Interactions in the Airways
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 4 of 5 Gerhard Walzl, Stellenbosch University, South Africa Human TB Treatment Response Studies Using PET/CT Imaging: Inconvenient Observations
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 5 of 5 Wendy A. Burgers, University of Cape Town, South Africa Short Talk: Defects in Multiple Mycobacterial T Helper Subsets in Blood and Lungs in Early HIV Infection
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 4 Paul Kaye, University of York, UK Understanding Granuloma Heterogeneity in Visceral Leishmaniasis
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 4 Martin Rottenberg, Karolinska Institutet, Sweden SOCS3 in either Myeloid or T Cells Conveys Resistance to Infection with Mycobacterium tuberculosis
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 4 Jean-Laurent Casanova, Rockefeller University, USA Toward a Genetic Theory of Childhood Infectious Diseases
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 4 Evelina Guirado, Ohio State University, USA Short Talk: Characterization of Host and Microbial Determinants in Individuals with Latent Tuberculosis Infection Using a Human Granuloma Model
Friday, January 23 \| 9:40AM - 10:00AM Coffee Break Room: Sweeney Ballroom Foyer
Friday, January 23 \| 11:15AM - 12:15PM Lunch
Friday, January 23 \| 12:00PM - 2:30PM Poster Session 1 Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 1 of 9 * Christopher M. Sassetti, University of Massachusetts Medical School, USA
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 2 of 9 * Brian C. VanderVen, Cornell University, USA Chemical Screening against Mycobacterium tuberculosis in Macrophages Identifies Inhibitors of Cholesterol Utilization
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 3 of 9 Frederick K. Balagaddé, K-RITH KwaZulu-Natal Research Institute for TB & HIV, South Africa Confinement-Induced Drug-Tolerance in Microfluidic Bioreactors
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 4 of 9 Robert Blomgran, Linköping University, Sweden Pharmacological Inhibition of mTORC1 Is Not the Treatment for HIV Mycobacterium tuberculosis Co-Infection
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 5 of 9 Meenal Datta, Massachusetts General Hospital/Harvard Medical School, USA Anti-VEGF Treatment Normalizes Tuberculosis Granuloma Vasculature and Improves Small Molecule Delivery
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 6 of 9 Scott M. Irwin, Colorado State University, USA Bedaquiline and its Metabolite Display Reduced Penetration into Caseous Necrotic Pulmonary Lesions in C3HeB/FeJ Mice
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 7 of 9 Ekta Lachmandas, Radboud University Medical Center, Netherlands Rewiring of Cellular Metabolism via the AKT/mTOR Pathway Forms the Basis of Host Defense against Mycobacterium tuberculosis
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 8 of 9 Tige R. Rustad, Seattle BioMed, USA The Wiring Diagram of Mycobacterium tuberculosis: Generating and Using an Experimentally-Derived Transcriptional Regulatory Map
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis Room: Sweeney Ballroom A-D Speaker 9 of 9 Suraj P. Parihar, University of Cape Town, South Africa Role of Statins against Mycobacterium tuberculosis Infection
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 6 * Matyas Sandor, University of Wisconsin, USA
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 6 Matthew McPeek, East Carolina University, USA MicroRNAs Targeting PPAR? Pathways Are Elevated in Bronchoalveolar Lavage (BAL) Cells from Sarcoidosis Patients and from Mice Bearing Carbon Nanotube Induced Granulomas
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 6 Marie Lipoldova, Institute of Molecular Genetics, Czech Republic Analysis of Granuloma Formation and Characteristics Using Defined Genomic Constructs
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 6 Deepak Kaushal, Texas Biomedical Research Institute, USA Role of Sensor Kinase DosS in Virulence of Mycobacterium tuberculosis in C3HeB/FeJ Mice with Classical Granulomatous Lesions
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 6 Teresa A. Hudock, Tulane National Primate Research Center, USA Transcriptome Analysis of Mycobacterium tuberculosis in Primate Lung Granulomas
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology This session is from Granulomas Room: Coronado / DeVargas Speaker 6 of 6 Albert Byungyun Jeon, Colorado State University, USA Reversal of Phenotypic and Genotypic Antimicrobial Drug Resistance in Mycobacterium tuberculosis with 2 Aminoimadazole-Based Small Molecule Adjuvants
Friday, January 23 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 1 of 5 * Henry Charles Mwandumba, Liverpool School of Tropical Medicine, UK
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 2 of 5 Thomas R. Hawn, University of Washington, USA Innate Immunogenetics of TB in Humans
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 3 of 5 Vojo Deretic, University of New Mexico Health Sciences Center, USA Autophagy in Tuberculosis
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 4 of 5 Sabine Ehrt, Weill Cornell Medical College, USA Survival in the Phagosome: Resist to Persist
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 5 of 5 Ludovic P. Desvignes, New York University School of Medicine, USA Short Talk: Dynamics of Early Growth and Spread of Mycobacterium tuberculosis in vivo Reveal Sequential Infection of Myeloid Cell Populations
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 5 * Paul Kaye, University of York, UK
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 5 Margherita T. Cantorna, Pennsylvania State University, USA The Implications of Vitamin D Status on T Cells, the Microbiome and Crohn’s Disease
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 5 R Balfour Balfour Sartor, University of North Carolina - Chapel Hill, USA Granulomatous Enterocolitis and Inflammation in Crohn's Disease: Intersection of Functionally Abnormal Bacteria and Defective Innate and Adaptive Immune Responses
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 5 Andreea Geamanu, Wayne State University, USA Short Talk: Metabolomics Links Alterations in Fatty Acid Metabolism, Inflammation and Gut Microbiota in Sarcoidosis
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 5 Damien J.C. Montamat-Sicotte, McGill Research Institute RI-MUHC, Canada Short Talk: NOD2: Innate Immunity, Bacterial Infection and Chronic Inflammation
Saturday, January 24 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 1 of 8 * Vishva M. Dixit, Genentech, Inc., USA
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 2 of 8 JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA Heterogeneity: Global and Local
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 3 of 8 Gilla Kaplan, University of Cape Town, South Africa Lesion-Specific Immune Activation in Granulomas of Patients with Pulmonary Tuberculosis
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 4 of 8 Thomas A. Wynn, Pfizer, USA Mechanisms of Fibrosis
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 5 of 8 Lalita Ramakrishnan, University of Cambridge, UK Mechanisms and Consequences of Tuberculous Granuloma Necrosis
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 6 of 8 Shahin Shafiani, Center for Infectious Disease Research, USA Short Talk: Foxp3+ Regulatory T Cells Are Host-Protective during Chronic Tuberculosis and Promote a Pathogen-Specific Immune Response
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 7 of 8 Philana Ling Lin, University of Pittsburgh, USA Short Talk: Spatial Patterns of Granuloma Development Differ between Infection and Reactivation
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 8 of 8 Igor B. Kramnik, Boston University, USA Short Talk: Necrosis in Granulomas: Mechanism and Therapeutic Approaches
Saturday, January 24 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom Foyer
Saturday, January 24 \| 11:00AM - 5:00PM On Own for Lunch
Saturday, January 24 \| 11:30AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakouts
Saturday, January 24 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Saturday, January 24 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 1 of 5 * Jennifer Philips, Washington University School of Medicine, USA
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 2 of 5 Sarah M. Fortune, Harvard TH Chan School of Public Health, USA Dissecting Bacterial Survival, Replication and Mutation in the Host Environment
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 3 of 5 W. Henry Boom, Case Western Reserve University, USA Evasion of T Cell Immunity by Mycobacterium tuberculosis
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 4 of 5 Christopher M. Sassetti, University of Massachusetts Medical School, USA Systematic Genetic Approaches to Understand TB Pathogenesis
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 5 of 5 Jordi B. Torrelles, Ohio State University, USA Short Talk: Lung Mucosa Lining Fluid Modifies Mycobacterium tuberculosis to Reprogram Neutrophil Killing Mechanisms to Preserve the Anti-Inflammatory Integrity of the Lung
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 5 * P'ng Loke, New York University School of Medicine, USA
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 5 Peter J. Murray, Max-Planck-Institut für Biochemie, Germany Amino Acid Metabolism by Innate Immune Cells in Granulomatous Inflammation
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 5 Frederic Geissmann, Memorial Sloan Kettering Cancer Center, USA Langerhans Cell Histiocytosis, a Pediatric Granulomatous Disease
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 5 Vishva M. Dixit, Genentech, Inc., USA Necroptosis - Role in Inflammation
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 5 Keke C. Fairfax, University of Utah, USA Short Talk: Schistosoma mansoni Infection Induces Anti-Atherogenic Transcriptional Changes in Hepatic Macrophages
Saturday, January 24 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Saturday, January 24 \| 7:30PM - 10:00PM Poster Session 2 Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 1 of 7 * Tom H. M. Ottenhoff, Leiden University Medical Center, Netherlands
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 2 of 7 Thomas J. Scriba, University of Cape Town, South Africa Prospective Correlates of Risk of TB Disease
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 3 of 7 Katrin D. Mayer-Barber, NIAID, National Institutes of Health, USA Inflammatory Cytokine Networks during TB
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 4 of 7 January Weiner, Max Planck Institute of Infection Biology, Germany TB Biomarkers Across Cohorts and Sample Types
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 5 of 7 Joel D. Ernst, University of California, San Francisco, USA Antigen Conservation and Diversity in Human Tuberculosis
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 6 of 7 Rustin Lovewell, University of Massachusetts Medical School, USA Short Talk: The Role of Neutrophils in Progressive Tuberculosis
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 7 of 7 Diane Joyce Ordway, Colorado State University, USA Short Talk: BCG Efficacy in Guinea Pigs Naturally Exposed to Patients with Tuberculosis
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 6 * Padmini Salgame, Rutgers University, USA
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 6 Edward J. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany Metabolic Reprogramming of Myeloid Cells during Granuloma Formation
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 6 William C. Gause, Rutgers New Jersey Medical School, USA Regulation of Type-2 Inflammation and Pathology in the Lung and Gut during Nematode Infection
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 6 P'ng Loke, New York University School of Medicine, USA Alternatively Activated Macrophages during Granuloma Formation in Schistosomiasis
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 6 Michael H. Hsieh, Children's National Medical Center, USA Type-2 Granulomas and Bladder Cancer
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity This session is from Granulomas Room: Coronado / DeVargas Speaker 6 of 6 Jessica C. Jang, University of California, Riverside, USA Short Talk: Human Resistin Is Induced in Multiple Helminth Infections and Promotes Proinflammatory Cytokines and Monocyte-Rich Lung Granulomas
Sunday, January 25 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom Foyer
Sunday, January 25 \| 11:15AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 11:15AM - 5:00PM On Own for Lunch
Sunday, January 25 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 1 of 5 * Shabaana A. Khader, Washington University School of Medicine, USA
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 2 of 5 John R. Chan, Albert Einstein College of Medicine, USA B Cells Promote Granulomatous Inflammation during Chronic Mycobacterium tuberculosis Infection
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 3 of 5 Andrea M. Cooper, University of Leicester, UK The Role of B Cells in Defining T Cell Location in TB
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 4 of 5 Galit Alter, MIT and Harvard University, USA A Case for Antibody Fc-Effector Function in Tb Containment
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 5 of 5 Alan Bénard, Institut de Pharmacologie et de Biologie Structurale, France Short Talk: B Cells Modulate Inflammation during Mycobacterium tuberculosis Infection in a MyD88- and Type I Interferon-Dependent Manner
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 5 * Daniel L. Barber, NIAID, National Institutes of Health, USA
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 5 Randall J. Basaraba, Colorado State University, USA Granuloma-Targeted Therapy in the Treatment of Tuberculosis
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 5 Andrew P. Fontenot, University of Colorado Denver, USA Gene-Environment Interactions and the Development of Chronic Beryllium Disease
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 5 Luigina Romani, University di Perugia, Italy Chronic Inflammation in Fungal Diseases: From Basic Science to Therapeutic Intervention
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 5 Bryce C. Asay, Colorado State University, USA Short Talk: Heterogeneity in Lesion Types in C3HeB/FeJ Mice Is Modulated by Specific Characteristics of the Mycobacterium tuberculosis Strain Used
Sunday, January 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Sunday, January 25 \| 7:30PM - 10:00PM Poster Session 3 Room: Sweeney F, Main Level Breakouts
Monday, January 26 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 1 of 7 * Thomas Evans, TomegaVax, USA
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 2 of 7 Denise Kirschner, University of Michigan, USA A Novel Two-Pronged Approach to Biomarker Discovery in Tuberculosis
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 3 of 7 Willem A. Hanekom, Bill & Melinda Gates Foundation, USA Vaccines against TB: Where Are We Going?
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 4 of 7 D. Branch Moody, Brigham and Women's Hospital, USA Building Technology-Based T Cell Response to Non-Polymorphic CD1 Proteins
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 5 of 7 Robert A. Seder, NIAID, National Institutes of Health, USA What Is Needed to Protect Against TB?
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 6 of 7 Stephen M. Carpenter, Regeneron Pharmaceuticals, USA Short Talk: Heavily-Armed but Outnumbered: A Selective Loss of Memory CD8+ T Cells during Tuberculosis May Eclipse the Benefit of Vaccination
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines Room: Sweeney Ballroom A-D Protection against TB Speaker 7 of 7 Guangwu Xu, Vaccine & Gene Therapy Inst, and the Oregon National Primate Research Ctr, OHSU, USA Short Talk: Cytomegalovirus Vector-Based Tuberculosis Vaccines Provide Superior Protection to BCG after Intra-Bronchial mTb Challenge of Indian-Origin Rhesus macaques
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 7 * Andrew P. Fontenot, University of Colorado Denver, USA
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 7 Annemarie H. Meijer, Leiden University, Netherlands In vivo Study of Anti-Mycobacterial Autophagy and Granuloma Formation in the Zebrafish Model
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 7 Ronald N. Germain, NIAID, National Institutes of Health, USA Live Imaging Anti-Mycobacterial Immunity
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 7 Matyas Sandor, University of Wisconsin, USA Mycobacterial Granuloma Dynamics: Repopulation, Reformation and Cellular Traffic
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 7 Steven M. Holland, NIAID, National Institutes of Health, USA Genetics and Treatment of Chronic Granulomatous Disease
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 6 of 7 Elsje Pienaar, University of Michigan, USA Short Talk: Interplay between Mycobacterial Metabolism and Granuloma Dynamics in Tuberculosis
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment This session is from Granulomas Room: Coronado / DeVargas Speaker 7 of 7 David M. Tobin, Duke University School of Medicine, USA Short Talk: Interception of Host Angiogenic Signaling Limits Mycobacterial Growth
Monday, January 26 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom Foyer
Monday, January 26 \| 11:15AM - 2:30PM On Own for Lunch
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational This session is from Granulomas Room: Coronado / DeVargas Speaker 1 of 6 * David M. Tobin, Duke University School of Medicine, USA
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational This session is from Granulomas Room: Coronado / DeVargas Speaker 2 of 6 Delia Goletti, National Institute for Infectious Diseases, Italy Can Blood or Urine IP-10 Discriminate between Active and Non Active Tuberculosis in Children from High Endemic Areas?
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational This session is from Granulomas Room: Coronado / DeVargas Speaker 3 of 6 Lobelia Samavati, Wayne State University School of Medicine, USA Development of a Sarcoidosis Library to Detect Sarcoidosis and Tuberculosis by a Panel of Novel Biomarkers
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational This session is from Granulomas Room: Coronado / DeVargas Speaker 4 of 6 Daniel Torocsik, University of Debrecen, Hungary Immunohistochemical Characterization of FXIII-A+ Cells in Non-Infectious Granulomatous Skin Lesions
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational This session is from Granulomas Room: Coronado / DeVargas Speaker 5 of 6 Javeed Ali Shah, University of Washington, USA TOLLIP Variants Are Associated with Susceptibility to Leprosy and Dermal Expression of TOLLIP and IL-1Ra in Nepal
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational This session is from Granulomas Room: Coronado / DeVargas Speaker 6 of 6 Ho Namkoong, Keio University School of Medicine, Japan Clarithromycin Expands CD11b+Gr-1+Cells to Ameliorate Post-Influenza Pneumococcal Pneumonia
Monday, January 26 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 1 of 5 * Willem A. Hanekom, Bill & Melinda Gates Foundation, USA
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 2 of 5 Padmini Salgame, Rutgers University, USA TB and Worms
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 3 of 5 Hardy Kornfeld, University of Massachusetts Medical School, USA TB and Diabetes
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 4 of 5 Jovvian George Parakkal, New York Blood Center-LFKRI, USA Short Talk: Influence of Helminth Infections on the Innate and Adaptive Immune Responses to Pulmonary Tuberculosis
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 5 of 5 Robert J. Wilkinson, University of Cape Town, South Africa Talk Title to be Announced
Monday, January 26 \| 7:00PM - 7:30PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Sweeney Ballroom A-D
Monday, January 26 \| 7:30PM - 8:30PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Monday, January 26 \| 8:00PM - 11:00PM Entertainment Room: Sweeney F, Main Level Breakouts Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Monday, January 26 \| 8:00PM - 11:00PM Cash Bar Room: Sweeney F, Main Level Breakouts
Tuesday, January 27 \| 10:25AM - 10:25AM Departure *Session Chair.