Past Meeting | Keystone Symposia

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Tuberculosis: Immunity and Immune Evasion (2020A2)

Web Desc
Granulomas in Infectious and Non-Infectious Diseases joint with Host Response in Tuberculosis Organizer(s): Thomas A. Wynn, Paul Kaye and Vishva M. Dixit Date: January 22 - 27, 2015 Location: Santa Fe Community Convention Center, Santa Fe, NM, USA Sponsored by Genentech, Inc. Summary of Meeting: This meeting will address the basic mechanisms of granulomatous inflammation and will focus on several chronic inflammatory diseases in which persistent granuloma formation is the central pathogenic mechanism of disease. The meeting will run in parallel with another on “Host Response in Tuberculosis,” and will include two joint plenary sessions where both audiences will meet together. Granulomas form when the immune system attempts to wall-off substances that it perceives as foreign but is unable to eliminate. These substances include infectious organisms such as bacteria and fungi as well as other known foreign materials. In some cases, however, the offending antigen is unknown as in sarcoidosis. A granuloma is therefore a special type of inflammation, typically an organized collection of macrophages that occurs in a wide variety of infectious and non-infectious diseases including schistosomiasis, histoplasmosis, cryptococcosis, Crohn’s disease, sarcoidosis and rheumatoid arthritis. The goal of this Keystone Symposia meeting is to bring together researchers, clinicians and members of the pharmaceutical industry to discuss the basic mechanics of granuloma formation, elucidate common pathogenic mechanisms and identify novel areas of therapeutic intervention for the large number of chronic granulomatous diseases. Scholarship Deadline: September 29 2014 Discounted Abstract Deadline: September 29 2014 Abstract Deadline: October 22 2014 Discounted Registration Deadline: November 20 2014 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Genentech, Inc. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Granulomas in Infectious and Non-Infectious Diseases

joint with Host Response in Tuberculosis

Organizer(s): Thomas A. Wynn, Paul Kaye and Vishva M. Dixit

Date: January 22 - 27, 2015
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA

Program


Thursday, January 22 \| 4:00PM - 8:00PM Arrival and Registration Room: Sweeney Ballroom Foyer
Thursday, January 22 \| 6:00PM - 8:00PM Welcome Mixer Room: Sweeney F No registration fees are used to fund alcohol served at this function.
Friday, January 23 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 7:30AM - 8:00AM Poster Setup Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 8:00AM - 5:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 8:00AM - 9:00AM Keynote Address Room: Coronado / DeVargas Speaker 1 of 2 * Thomas A. Wynn, Pfizer, USA
Friday, January 23 \| 8:00AM - 9:00AM Keynote Address Room: Coronado / DeVargas Speaker 2 of 2 Alberto Mantovani, Humanitas University, Italy Macrophage Plasticity and Polarization in Granulomatous Inflammation
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity Room: Coronado / DeVargas Speaker 1 of 4 Paul Kaye, University of York, UK Understanding Granuloma Heterogeneity in Visceral Leishmaniasis
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity Room: Coronado / DeVargas Speaker 2 of 4 Martin Rottenberg, Karolinska Institutet, Sweden SOCS3 in either Myeloid or T Cells Conveys Resistance to Infection with Mycobacterium tuberculosis
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity Room: Coronado / DeVargas Speaker 3 of 4 Jean-Laurent Casanova, Rockefeller University, USA Toward a Genetic Theory of Childhood Infectious Diseases
Friday, January 23 \| 9:00AM - 11:15AM Granulomas Associated with Type-1 Immunity Room: Coronado / DeVargas Speaker 4 of 4 Evelina Guirado, Ohio State University, USA Short Talk: Characterization of Host and Microbial Determinants in Individuals with Latent Tuberculosis Infection Using a Human Granuloma Model
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung This session is from Tuberculosis Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 1 of 5 * Alan Sher, NIAID, National Institutes of Health, USA
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung This session is from Tuberculosis Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 2 of 5 David M. Lewinsohn, Oregon Health & Science University, USA MAITs and Protection Against TB
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung This session is from Tuberculosis Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 3 of 5 Henry Charles Mwandumba, Liverpool School of Tropical Medicine, UK TB/HIV Interactions in the Airways
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung This session is from Tuberculosis Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 4 of 5 Gerhard Walzl, Stellenbosch University, South Africa Human TB Treatment Response Studies Using PET/CT Imaging: Inconvenient Observations
Friday, January 23 \| 9:00AM - 11:15AM Immunity in the Lung This session is from Tuberculosis Room: Sweeney Ballroom A-D Events in the airway and interactions with early cells influence outcome. Speaker 5 of 5 Wendy A. Burgers, University of Cape Town, South Africa Short Talk: Defects in Multiple Mycobacterial T Helper Subsets in Blood and Lungs in Early HIV Infection
Friday, January 23 \| 9:40AM - 10:00AM Coffee Break Room: Sweeney Ballroom Foyer
Friday, January 23 \| 11:15AM - 12:15PM Lunch
Friday, January 23 \| 12:00PM - 2:30PM Poster Session 1 Room: Sweeney F, Main Level Breakouts
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology Room: Coronado / DeVargas Speaker 1 of 6 * Matyas Sandor, University of Wisconsin, USA
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology Room: Coronado / DeVargas Speaker 2 of 6 Matthew McPeek, East Carolina University, USA MicroRNAs Targeting PPAR? Pathways Are Elevated in Bronchoalveolar Lavage (BAL) Cells from Sarcoidosis Patients and from Mice Bearing Carbon Nanotube Induced Granulomas
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology Room: Coronado / DeVargas Speaker 3 of 6 Marie Lipoldova, Institute of Molecular Genetics, Czech Republic Analysis of Granuloma Formation and Characteristics Using Defined Genomic Constructs
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology Room: Coronado / DeVargas Speaker 4 of 6 Deepak Kaushal, Texas Biomedical Research Institute, USA Role of Sensor Kinase DosS in Virulence of Mycobacterium tuberculosis in C3HeB/FeJ Mice with Classical Granulomatous Lesions
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology Room: Coronado / DeVargas Speaker 5 of 6 Teresa A. Hudock, Tulane National Primate Research Center, USA Transcriptome Analysis of Mycobacterium tuberculosis in Primate Lung Granulomas
Friday, January 23 \| 2:30PM - 4:30PM Workshop 1: Basic Biology Room: Coronado / DeVargas Speaker 6 of 6 Albert Byungyun Jeon, Colorado State University, USA Reversal of Phenotypic and Genotypic Antimicrobial Drug Resistance in Mycobacterium tuberculosis with 2 Aminoimadazole-Based Small Molecule Adjuvants
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 1 of 9 * Christopher M. Sassetti, University of Massachusetts Medical School, USA
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 2 of 9 * Brian C. VanderVen, Cornell University, USA Chemical Screening against Mycobacterium tuberculosis in Macrophages Identifies Inhibitors of Cholesterol Utilization
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 3 of 9 Frederick K. Balagaddé, K-RITH KwaZulu-Natal Research Institute for TB & HIV, South Africa Confinement-Induced Drug-Tolerance in Microfluidic Bioreactors
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 4 of 9 Robert Blomgran, Linköping University, Sweden Pharmacological Inhibition of mTORC1 Is Not the Treatment for HIV Mycobacterium tuberculosis Co-Infection
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 5 of 9 Meenal Datta, Massachusetts General Hospital/Harvard Medical School, USA Anti-VEGF Treatment Normalizes Tuberculosis Granuloma Vasculature and Improves Small Molecule Delivery
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 6 of 9 Scott M. Irwin, Colorado State University, USA Bedaquiline and its Metabolite Display Reduced Penetration into Caseous Necrotic Pulmonary Lesions in C3HeB/FeJ Mice
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 7 of 9 Ekta Lachmandas, Radboud University Medical Center, Netherlands Rewiring of Cellular Metabolism via the AKT/mTOR Pathway Forms the Basis of Host Defense against Mycobacterium tuberculosis
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 8 of 9 Tige R. Rustad, Seattle BioMed, USA The Wiring Diagram of Mycobacterium tuberculosis: Generating and Using an Experimentally-Derived Transcriptional Regulatory Map
Friday, January 23 \| 2:30PM - 4:30PM Workshop: Novel Approaches to Treatment of Tuberculosis This session is from Tuberculosis Room: Sweeney Ballroom A-D Speaker 9 of 9 Suraj P. Parihar, University of Cape Town, South Africa Role of Statins against Mycobacterium tuberculosis Infection
Friday, January 23 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease Room: Coronado / DeVargas Speaker 1 of 5 * Paul Kaye, University of York, UK
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease Room: Coronado / DeVargas Speaker 2 of 5 Margherita T. Cantorna, Pennsylvania State University, USA The Implications of Vitamin D Status on T Cells, the Microbiome and Crohn’s Disease
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease Room: Coronado / DeVargas Speaker 3 of 5 R Balfour Balfour Sartor, University of North Carolina - Chapel Hill, USA Granulomatous Enterocolitis and Inflammation in Crohn's Disease: Intersection of Functionally Abnormal Bacteria and Defective Innate and Adaptive Immune Responses
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease Room: Coronado / DeVargas Speaker 4 of 5 Andreea Geamanu, Wayne State University, USA Short Talk: Metabolomics Links Alterations in Fatty Acid Metabolism, Inflammation and Gut Microbiota in Sarcoidosis
Friday, January 23 \| 5:00PM - 7:00PM Infectious and Non-Infectious Granulomatous Disease Room: Coronado / DeVargas Speaker 5 of 5 Damien J.C. Montamat-Sicotte, McGill Research Institute RI-MUHC, Canada Short Talk: NOD2: Innate Immunity, Bacterial Infection and Chronic Inflammation
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection This session is from Tuberculosis Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 1 of 5 * Henry Charles Mwandumba, Liverpool School of Tropical Medicine, UK
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection This session is from Tuberculosis Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 2 of 5 Thomas R. Hawn, University of Washington, USA Innate Immunogenetics of TB in Humans
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection This session is from Tuberculosis Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 3 of 5 Vojo Deretic, University of New Mexico Health Sciences Center, USA Autophagy in Tuberculosis
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection This session is from Tuberculosis Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 4 of 5 Sabine Ehrt, Weill Cornell Medical College, USA Survival in the Phagosome: Resist to Persist
Friday, January 23 \| 5:00PM - 7:00PM Early Events after TB Infection This session is from Tuberculosis Room: Sweeney Ballroom A-D Early events in the infectious process. Speaker 5 of 5 Ludovic P. Desvignes, New York University School of Medicine, USA Short Talk: Dynamics of Early Growth and Spread of Mycobacterium tuberculosis in vivo Reveal Sequential Infection of Myeloid Cell Populations
Saturday, January 24 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 1 of 8 * Vishva M. Dixit, Genentech, Inc., USA
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 2 of 8 JoAnne L. Flynn, University of Pittsburgh School of Medicine, USA Heterogeneity: Global and Local
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 3 of 8 Gilla Kaplan, University of Cape Town, South Africa Lesion-Specific Immune Activation in Granulomas of Patients with Pulmonary Tuberculosis
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 4 of 8 Thomas A. Wynn, Pfizer, USA Mechanisms of Fibrosis
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 5 of 8 Lalita Ramakrishnan, University of Cambridge, UK Mechanisms and Consequences of Tuberculous Granuloma Necrosis
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 6 of 8 Shahin Shafiani, Center for Infectious Disease Research, USA Short Talk: Foxp3+ Regulatory T Cells Are Host-Protective during Chronic Tuberculosis and Promote a Pathogen-Specific Immune Response
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 7 of 8 Philana Ling Lin, University of Pittsburgh, USA Short Talk: Spatial Patterns of Granuloma Development Differ between Infection and Reactivation
Saturday, January 24 \| 8:00AM - 11:30AM Pathogenic Mechanisms in Chronic Granulomatous Disease (Join t) Room: Sweeney Ballroom A-D Speaker 8 of 8 Igor B. Kramnik, Boston University, USA Short Talk: Necrosis in Granulomas: Mechanism and Therapeutic Approaches
Saturday, January 24 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom Foyer
Saturday, January 24 \| 11:00AM - 5:00PM On Own for Lunch
Saturday, January 24 \| 11:30AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakouts
Saturday, January 24 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Saturday, January 24 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation Room: Coronado / DeVargas Speaker 1 of 5 * P'ng Loke, New York University School of Medicine, USA
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation Room: Coronado / DeVargas Speaker 2 of 5 Peter J. Murray, Max-Planck-Institut für Biochemie, Germany Amino Acid Metabolism by Innate Immune Cells in Granulomatous Inflammation
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation Room: Coronado / DeVargas Speaker 3 of 5 Frederic Geissmann, Memorial Sloan Kettering Cancer Center, USA Langerhans Cell Histiocytosis, a Pediatric Granulomatous Disease
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation Room: Coronado / DeVargas Speaker 4 of 5 Vishva M. Dixit, Genentech, Inc., USA Necroptosis - Role in Inflammation
Saturday, January 24 \| 5:00PM - 7:00PM Role of Myeloid Cells in Granuloma Formation Room: Coronado / DeVargas Speaker 5 of 5 Keke C. Fairfax, University of Utah, USA Short Talk: Schistosoma mansoni Infection Induces Anti-Atherogenic Transcriptional Changes in Hepatic Macrophages
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells This session is from Tuberculosis Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 1 of 5 * Jennifer Philips, Washington University School of Medicine, USA
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells This session is from Tuberculosis Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 2 of 5 Sarah M. Fortune, Harvard TH Chan School of Public Health, USA Dissecting Bacterial Survival, Replication and Mutation in the Host Environment
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells This session is from Tuberculosis Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 3 of 5 W. Henry Boom, Case Western Reserve University, USA Evasion of T Cell Immunity by Mycobacterium tuberculosis
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells This session is from Tuberculosis Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 4 of 5 Christopher M. Sassetti, University of Massachusetts Medical School, USA Systematic Genetic Approaches to Understand TB Pathogenesis
Saturday, January 24 \| 5:00PM - 7:00PM Bacterial Interactions with Host Cells This session is from Tuberculosis Room: Sweeney Ballroom A-D Mycobacterium tuberculosis interactions with host Speaker 5 of 5 Jordi B. Torrelles, Ohio State University, USA Short Talk: Lung Mucosa Lining Fluid Modifies Mycobacterium tuberculosis to Reprogram Neutrophil Killing Mechanisms to Preserve the Anti-Inflammatory Integrity of the Lung
Saturday, January 24 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Saturday, January 24 \| 7:30PM - 10:00PM Poster Session 2 Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity Room: Coronado / DeVargas Speaker 1 of 6 * Padmini Salgame, Rutgers University, USA
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity Room: Coronado / DeVargas Speaker 2 of 6 Edward J. Pearce, Max Planck Institute of Immunobiology and Epigenetics, Germany Metabolic Reprogramming of Myeloid Cells during Granuloma Formation
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity Room: Coronado / DeVargas Speaker 3 of 6 William C. Gause, Rutgers New Jersey Medical School, USA Regulation of Type-2 Inflammation and Pathology in the Lung and Gut during Nematode Infection
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity Room: Coronado / DeVargas Speaker 4 of 6 P'ng Loke, New York University School of Medicine, USA Alternatively Activated Macrophages during Granuloma Formation in Schistosomiasis
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity Room: Coronado / DeVargas Speaker 5 of 6 Michael H. Hsieh, Children's National Medical Center, USA Type-2 Granulomas and Bladder Cancer
Sunday, January 25 \| 8:00AM - 11:00AM Granulomas Associated with Type-2 Immunity Room: Coronado / DeVargas Speaker 6 of 6 Jessica C. Jang, University of California, Riverside, USA Short Talk: Human Resistin Is Induced in Multiple Helminth Infections and Promotes Proinflammatory Cytokines and Monocyte-Rich Lung Granulomas
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 1 of 7 * Tom H. M. Ottenhoff, Leiden University Medical Center, Netherlands
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 2 of 7 Thomas J. Scriba, University of Cape Town, South Africa Prospective Correlates of Risk of TB Disease
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 3 of 7 Katrin D. Mayer-Barber, NIAID, National Institutes of Health, USA Inflammatory Cytokine Networks during TB
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 4 of 7 January Weiner, Max Planck Institute of Infection Biology, Germany TB Biomarkers Across Cohorts and Sample Types
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 5 of 7 Joel D. Ernst, University of California, San Francisco, USA Antigen Conservation and Diversity in Human Tuberculosis
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 6 of 7 Rustin Lovewell, University of Massachusetts Medical School, USA Short Talk: The Role of Neutrophils in Progressive Tuberculosis
Sunday, January 25 \| 8:00AM - 11:15AM Risk of TB Disease This session is from Tuberculosis Room: Sweeney Ballroom A-D Factors that influence risk of disease Speaker 7 of 7 Diane Joyce Ordway, Colorado State University, USA Short Talk: BCG Efficacy in Guinea Pigs Naturally Exposed to Patients with Tuberculosis
Sunday, January 25 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom Foyer
Sunday, January 25 \| 11:00AM - 1:00PM Poster Setup Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 11:00AM - 5:00PM On Own for Lunch
Sunday, January 25 \| 1:00PM - 10:00PM Poster Viewing Room: Sweeney F, Main Level Breakouts
Sunday, January 25 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung Room: Coronado / DeVargas Speaker 1 of 5 * Daniel L. Barber, NIAID, National Institutes of Health, USA
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung Room: Coronado / DeVargas Speaker 2 of 5 Randall J. Basaraba, Colorado State University, USA Granuloma-Targeted Therapy in the Treatment of Tuberculosis
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung Room: Coronado / DeVargas Speaker 3 of 5 Andrew P. Fontenot, University of Colorado Denver, USA Gene-Environment Interactions and the Development of Chronic Beryllium Disease
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung Room: Coronado / DeVargas Speaker 4 of 5 Luigina Romani, University di Perugia, Italy Chronic Inflammation in Fungal Diseases: From Basic Science to Therapeutic Intervention
Sunday, January 25 \| 5:00PM - 7:00PM Granulomatous Diseases of the Lung Room: Coronado / DeVargas Speaker 5 of 5 Bryce C. Asay, Colorado State University, USA Short Talk: Heterogeneity in Lesion Types in C3HeB/FeJ Mice Is Modulated by Specific Characteristics of the Mycobacterium tuberculosis Strain Used
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB This session is from Tuberculosis Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 1 of 5 * Shabaana A. Khader, Washington University School of Medicine, USA
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB This session is from Tuberculosis Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 2 of 5 John R. Chan, Albert Einstein College of Medicine, USA B Cells Promote Granulomatous Inflammation during Chronic Mycobacterium tuberculosis Infection
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB This session is from Tuberculosis Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 3 of 5 Andrea M. Cooper, University of Leicester, UK The Role of B Cells in Defining T Cell Location in TB
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB This session is from Tuberculosis Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 4 of 5 Galit Alter, MIT and Harvard University, USA A Case for Antibody Fc-Effector Function in Tb Containment
Sunday, January 25 \| 5:00PM - 7:00PM B Cells Responses to TB This session is from Tuberculosis Room: Sweeney Ballroom A-D The neglected lymphocyte in TB Speaker 5 of 5 Alan Bénard, Institut de Pharmacologie et de Biologie Structurale, France Short Talk: B Cells Modulate Inflammation during Mycobacterium tuberculosis Infection in a MyD88- and Type I Interferon-Dependent Manner
Sunday, January 25 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Sunday, January 25 \| 7:30PM - 10:00PM Poster Session 3 Room: Sweeney F, Main Level Breakouts
Monday, January 26 \| 7:00AM - 8:00AM Breakfast Room: Sweeney F, Main Level Breakouts
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 1 of 7 * Andrew P. Fontenot, University of Colorado Denver, USA
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 2 of 7 Annemarie H. Meijer, Leiden University, Netherlands In vivo Study of Anti-Mycobacterial Autophagy and Granuloma Formation in the Zebrafish Model
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 3 of 7 Ronald N. Germain, NIAID, National Institutes of Health, USA Live Imaging Anti-Mycobacterial Immunity
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 4 of 7 Matyas Sandor, University of Wisconsin, USA Mycobacterial Granuloma Dynamics: Repopulation, Reformation and Cellular Traffic
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 5 of 7 Steven M. Holland, NIAID, National Institutes of Health, USA Genetics and Treatment of Chronic Granulomatous Disease
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 6 of 7 Elsje Pienaar, University of Michigan, USA Short Talk: Interplay between Mycobacterial Metabolism and Granuloma Dynamics in Tuberculosis
Monday, January 26 \| 8:00AM - 11:15AM Computational Modeling, Imaging and Treatment Room: Coronado / DeVargas Speaker 7 of 7 David M. Tobin, Duke University School of Medicine, USA Short Talk: Interception of Host Angiogenic Signaling Limits Mycobacterial Growth
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 1 of 7 * Thomas Evans, TomegaVax, USA
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 2 of 7 Denise Kirschner, University of Michigan, USA A Novel Two-Pronged Approach to Biomarker Discovery in Tuberculosis
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 3 of 7 Willem A. Hanekom, Bill & Melinda Gates Foundation, USA Vaccines against TB: Where Are We Going?
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 4 of 7 D. Branch Moody, Brigham and Women's Hospital, USA Building Technology-Based T Cell Response to Non-Polymorphic CD1 Proteins
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 5 of 7 Robert A. Seder, NIAID, National Institutes of Health, USA What Is Needed to Protect Against TB?
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 6 of 7 Stephen M. Carpenter, Regeneron Pharmaceuticals, USA Short Talk: Heavily-Armed but Outnumbered: A Selective Loss of Memory CD8+ T Cells during Tuberculosis May Eclipse the Benefit of Vaccination
Monday, January 26 \| 8:00AM - 11:15AM Protective Immunity and Vaccines This session is from Tuberculosis Room: Sweeney Ballroom A-D Protection against TB Speaker 7 of 7 Guangwu Xu, Vaccine & Gene Therapy Inst, and the Oregon National Primate Research Ctr, OHSU, USA Short Talk: Cytomegalovirus Vector-Based Tuberculosis Vaccines Provide Superior Protection to BCG after Intra-Bronchial mTb Challenge of Indian-Origin Rhesus macaques
Monday, January 26 \| 9:20AM - 9:40AM Coffee Break Room: Sweeney Ballroom Foyer
Monday, January 26 \| 11:15AM - 2:30PM On Own for Lunch
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational Room: Coronado / DeVargas Speaker 1 of 6 * David M. Tobin, Duke University School of Medicine, USA
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational Room: Coronado / DeVargas Speaker 2 of 6 Delia Goletti, National Institute for Infectious Diseases, Italy Can Blood or Urine IP-10 Discriminate between Active and Non Active Tuberculosis in Children from High Endemic Areas?
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational Room: Coronado / DeVargas Speaker 3 of 6 Lobelia Samavati, Wayne State University School of Medicine, USA Development of a Sarcoidosis Library to Detect Sarcoidosis and Tuberculosis by a Panel of Novel Biomarkers
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational Room: Coronado / DeVargas Speaker 4 of 6 Daniel Torocsik, University of Debrecen, Hungary Immunohistochemical Characterization of FXIII-A+ Cells in Non-Infectious Granulomatous Skin Lesions
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational Room: Coronado / DeVargas Speaker 5 of 6 Javeed Ali Shah, University of Washington, USA TOLLIP Variants Are Associated with Susceptibility to Leprosy and Dermal Expression of TOLLIP and IL-1Ra in Nepal
Monday, January 26 \| 2:30PM - 4:30PM Workshop 2: Clinical and Translational Room: Coronado / DeVargas Speaker 6 of 6 Ho Namkoong, Keio University School of Medicine, Japan Clarithromycin Expands CD11b+Gr-1+Cells to Ameliorate Post-Influenza Pneumococcal Pneumonia
Monday, January 26 \| 4:30PM - 5:00PM Coffee Available Room: Sweeney Ballroom Foyer
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 1 of 5 * Willem A. Hanekom, Bill & Melinda Gates Foundation, USA
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 2 of 5 Padmini Salgame, Rutgers University, USA TB and Worms
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 3 of 5 Hardy Kornfeld, University of Massachusetts Medical School, USA TB and Diabetes
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 4 of 5 Jovvian George Parakkal, New York Blood Center-LFKRI, USA Short Talk: Influence of Helminth Infections on the Innate and Adaptive Immune Responses to Pulmonary Tuberculosis
Monday, January 26 \| 5:00PM - 7:00PM TB and Co-Morbidities (Joint) Room: Sweeney Ballroom A-D Interactions of TB with other diseases Speaker 5 of 5 Robert J. Wilkinson, University of Cape Town, South Africa Talk Title to be Announced
Monday, January 26 \| 7:00PM - 7:30PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Sweeney Ballroom A-D
Monday, January 26 \| 7:30PM - 8:30PM Social Hour with Lite Bites Room: Sweeney F, Main Level Breakouts No registration fees are used to fund alcohol served at this function.
Monday, January 26 \| 8:00PM - 11:00PM Entertainment Room: Sweeney F, Main Level Breakouts Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Monday, January 26 \| 8:00PM - 11:00PM Cash Bar Room: Sweeney F, Main Level Breakouts
Tuesday, January 27 \| 10:25AM - 10:25AM Departure *Session Chair.