Web Desc
Mitochondria, Metabolism and Heart Failure
joint with Diabetes and Metabolic Dysfunction
Organizer(s): Richard N. Kitsis, Gerald W. Dorn II and Rong Tian
Date: January 27 - February 01, 2015
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA
Sponsored by Bayer HealthCare Pharmaceuticals and Takeda Pharmaceutical Company Limited. Supported by an educational donation provided by Amgen.
Summary of Meeting:
The most common causes of heart failure are coronary artery disease, high blood pressure and diabetes. Mitochondrial perturbations have been associated with heart failure itself, and with most of the other preceding risk factors. In some cases, mitochondrial dysfunction may play a causal role while in others mitochondria are a central target responsible for organ dysfunction. nderstanding mitochondrial pathophysiology and identifying ways to ameliorate mitochondrial dysfunction are critical to therapy for cardiovascular disease. Therefore, the overall objectives of this meeting are to: (1) Mechanistically connect the fundamental biology of metabolism and mitochondrial function with the pathogenesis of heart failure, a major cause of morbidity and mortality in the world; and (2) Increase basic understanding of metabolism and mitochondrial function using observations in cardiac muscle, a traditional platform for these studies. The ongoing convergence of the cardiac metabolism and mitochondrial biology fields provides a particularly cogent rationale for this meeting; moreover, large gaps of knowledge exist in this area such as the precise molecular signaling that connects metabolism and energy sensing with mitochondrial function, and the roles of basic mitochondrial processes (e.g., biogenesis, fission, fusion, mitophagy, maintenance of mitochondrial genome integrity) in metabolism and heart failure. These deficiencies in fundamentally important scientific knowledge and their clinical implications for a common and lethal disease confer exceptional significance on this conference. Opportunities for interdisciplinary interactions will be significantly enhanced by the concurrent meeting on “Diabetes and Metabolic Dysfunction,” which will share a keynote address and three plenary sessions.
Scholarship Deadline: October 1 2014
Discounted Abstract Deadline: October 1 2014
Abstract Deadline: October 28 2014
Discounted Registration Deadline: November 25 2014
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Educational donation provided by AmgenBayer HealthCare PharmaceuticalsTakeda Pharmaceutical Company Limited
We gratefully acknowledge additional support for this conference from:

American Heart Association's Councils on Basic CV Sciences, and CV Disease in the Young
HypOxygenJournal of Lipid Research
We gratefully acknowledge the generous grant for this conference provided by:

National Heart, Lung, and Blood Institute (NHLBI)
Grant No. 1R13HL126460-01
Funding for this conference was made possible (in part) by 1R13HL126460-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, January 27 | 4:00PM - 8:00PM
Arrival and Registration
Room: Sweeney Ballroom Foyer


Tuesday, January 27 | 6:00PM - 8:00PM
Welcome Mixer
Room: Sweeney F
No registration fees are used to fund alcohol served at this function.

Wednesday, January 28 | 7:00AM - 9:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 2:00PM - 3:00PM
Poster Setup
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 2:30PM - 3:00PM
Coffee Available
Room: Sweeney Ballroom Foyer


Wednesday, January 28 | 3:00PM - 10:00PM
Poster Viewing
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 3:00PM - 4:00PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 3
* Jeffrey E. Pessin, Albert Einstein College of Medicine, USA

Wednesday, January 28 | 3:00PM - 4:00PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 3
* Richard N. Kitsis, Albert Einstein College of Medicine, USA

Wednesday, January 28 | 3:00PM - 4:00PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 3
Helen H. Hobbs, University of Texas Southwestern Medical Center, USA
Journal of Lipid Research Lectureship Introduced by JLR Associate Editor, Ira Goldberg. Orchestrating Fatty Acid Flux to Adipose Tissue during Feast and Famine

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 5
* Rong Tian, University of Washington, USA

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 5
Christopher B. Newgard, Duke University Medical Center, USA
Role of the Gut Microbiota in the Pathogenesis and Treatment of Cardiometabolic Diseases

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 5
E. Dale Abel, University of Iowa, Carver College of Medicine, USA
Insulin Signaling in the Heart

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 5
Eric N. Olson, University of Texas Southwestern Medical Center, USA
Muscular 'Mediators' of Metabolism

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 5
Lawrence Kazak, McGill University, Canada
Regulation of Heat Production by Various Shades of Fat: A Novel Thermogenic Pathway in Beige Fat

Wednesday, January 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 7:30PM - 10:00PM
Poster Session 1
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 7
* Heidi M. McBride, McGill University, Canada

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 7
Richard J. Youle, NINDS, National Institutes of Health, USA
Damage Control: How PINK1 and Parkin Survey Mitochondrial Fidelity and Respond with Selective Autophagy

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 7
Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA
Roles of Lipid Droplet Lipolysis, Autophagy and Mitochondrial Fusion Dynamics in Fatty Acid Trafficking within Cells

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 7
Orian S. Shirihai, University of California, Los Angeles, USA
Mitochondrial Dynamics and Quality Control, a Conflict of Interest

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 7
Gerald W. Dorn, II, Washington University School of Medicine, USA
Mitochondrial Dynamics, Mitochondrial Quality Control and Heart Disease

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 7
Luca Scorrano, University of Padova, Italy
Keeping Mitochondria Cristae in Shape to Control Organ Damage and Metabolism

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 7 of 7
Peipei Ping, University of California, Los Angeles, USA
Data Science Approaches for Mitochondrial Discoveries

Thursday, January 29 | 9:50AM - 10:10AM
Coffee Break
Room: Sweeney Ballroom Foyer


Thursday, January 29 | 12:00PM - 1:00PM
Poster Setup
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 12:00PM - 4:30PM
On Own for Lunch


Thursday, January 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 4:00PM - 4:30PM
Coffee Available
Room: Sweeney Ballroom Foyer


Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
Room: Sweeney Ballroom C-E

Speaker 1 of 6
* Sihem Boudina, University of Utah School of Medicine, USA

Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
Room: Sweeney Ballroom C-E

Speaker 2 of 6
Rong Tian, University of Washington, USA
Metabolic Remodeling of the Heart

Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
Room: Sweeney Ballroom C-E

Speaker 3 of 6
E. Douglas Lewandowski, University of Illinois at Chicago College of Medicine, USA
Remodeled Metabolism In and Around the Failing Heart

Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
Room: Sweeney Ballroom C-E

Speaker 4 of 6
Daniel P. Kelly, University of Pennsylvania, USA
Deciphering the Metabolic Basis of Heart Failure

Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
Room: Sweeney Ballroom C-E

Speaker 5 of 6
Edward T. Chouchani, Dana-Farber Cancer Institute, USA
Short Talk: Ischemic Accumulation of Succinate Controls Reperfusion Injury through Mitochondrial ROS

Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
Room: Sweeney Ballroom C-E

Speaker 6 of 6
Benjamin A. Olenchock, Brigham and Women’s Hospital, USA
Short Talk: Inhibition of the Prolyl Hydroxylase EglN1 Is Sufficient for Local and Remote Cardiac Ischemic Protection: Role of Tryptophan Metabolism

Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 1 of 7
* Alan R. Saltiel, University of California, San Diego, USA


Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 2 of 7
Deborah M. Muoio, Duke University Medical Center, USA
Nutrient-Induced Mitochondrial Stress and Metabolic Inflexibility in Skeletal Muscle



Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 3 of 7
Morris J. Birnbaum, Uninversity of Pennsylvania and Pfizer, Inc, USA
Non-Autonomous Regulation of Hepatic Glucose Output by Insulin


Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 4 of 7
Domenico Accili, Columbia University, USA
FOXO Signaling and Hepatic Glucose Production


Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 5 of 7
Marc R. Montminy, The Salk Institute for Biological Studies, USA
Regulation of Hepatic Gluconeogenesis by the CREB Pathway


Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 6 of 7
Carl S. Thummel, University of Utah School of Medicine, USA
Short Talk: The Molecular Basis of MODY1 and its Regulation by HNF4


Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 7 of 7
Alexander S. Banks, Harvard Medical School, USA
Short Talk: Therapeutic Resolution of Insulin Resistance via MEK/ERK Inhibition and Reversal of PPARgamma Serine 273 Phosphorylation


Thursday, January 29 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts
No registration fees are used to fund alcohol served at this function.

Thursday, January 29 | 7:30PM - 10:00PM
Poster Session 2
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 1 of 8
* Konstantinos Drosatos, Temple University School of Medicine, USA

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 2 of 8
Roberta A. Gottlieb, Cedars-Sinai Medical Center, USA
Autophagy in Cardioprotection and Impact of Metabolic Syndrome

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 3 of 8
Åsa B. Gustafsson, University of California, San Diego, USA
MCL-1 as a Critical Regulator of Mitochondrial Function and Cell Death

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 4 of 8
Elizabeth Murphy, Cardiac Physiology Section Vascular Medicine Branch, NHLBI, NIH, USA
Calcium Regulation of Mitochondrial Function

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 5 of 8
Junichi Sadoshima, Rutgers New Jersey Medical School, USA
Ulk1 Plays a Crucial Role in Mitochondrial Autophagy in Cardiomyocytes

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 6 of 8
Christoph Maack, Universitätsklinikum des Saarlandes, Germany
Impact of the Mitochondrial/SR Interaction for Redox Regulation

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 7 of 8
Saptarsi M. Haldar, University of California, San Francisco, USA
Short Talk: Glucocorticoids Elicit Ergogenic Effects in Muscle via a Defined Transcriptional Pathway

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
Room: Sweeney Ballroom C-E

Speaker 8 of 8
Anja Karlstaedt, University of Texas Medical School at Houston, USA
Short Talk: Regulation of mTOR Activation during Acute Increases of Heart Work: The Role of Endogenous Substrates

Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 1 of 6
* Christopher B. Newgard, Duke University Medical Center, USA


Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 2 of 6
Ronald M. Evans, HHMI/The Salk Institute, USA
Nuclear Receptors and the Hunger Game: From Feast to Famine


Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 3 of 6
John F. Rawls, Duke University, USA
Microbial Regulation of Intestinal Lipid Metabolism and Gene Expression


Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 4 of 6
C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
New Insights into Insulin Signaling and Insulin Action in Muscle through Genetic Manipulation


Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 5 of 6
Gökhan S. Hotamisligil, Harvard School of Public Health, USA
Endoplasmic Reticulum and Mitochondria Integration in Response to Metabolic Stress


Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 6 of 6
Gerard Karsenty, Columbia University Medical Center, USA
A Crosstalk between Glucose Uptake and Runx2 Determines the Onset of Osteoblast Differentiation and the Extent of Bone Formation


Friday, January 30 | 9:40AM - 10:00AM
Coffee Break
Room: Sweeney Ballroom Foyer


Friday, January 30 | 11:15AM - 1:00PM
Poster Setup
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 12:00PM - 4:30PM
On Own for Lunch


Friday, January 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 1 of 9
* Jeffrey E. Pessin, Albert Einstein College of Medicine, USA

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 2 of 9
Ronald N. Margolis, NIDDK, National Institutes of Health, USA
Biomedical Big Data: Data Discovery and the Digital Enterprise

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 3 of 9
Abdelilah Arredouani, Qatar Foundation, Qatar
Non-Targeted Metabolomic Profiling Score Improves the Early Prediction of Type 2 Diabetes in the Prospective D.E.S.I.R. Study

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 4 of 9
Ida Donkin, Copenhagen University, Denmark
Spermatozoa from Lean and Obese Humans Carry Distinct Epigenetic Signatures

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 5 of 9
Olga Gupta, University of Texas Southwestern Medical Center, USA
Transcriptome Profiling of Omental Adipose Mesothelial Cells Reveals Differentially Expressed Transcripts Related to Inflammation

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 6 of 9
Ondrej Kuda, Academy of Sciences of the Czech Republic, Czech Republic
Metabolipidomical Profiling of Adipose Tissue during Fatty Acid Re-Esterification

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 7 of 9
Xiaofeng Xin, Massachusetts Institute of Technology, USA
Systems Biology of Obesity-Induced Hepatic Insulin Resistance

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 8 of 9
Adam R. Wende, University of Alabama at Birmingham, USA
DNA Methylation and Corresponding Gene Expression Changes in the Diabetic Heart

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 9 of 9
Dietrich Rein, Metanomics Health, Germany
Validation of a Metabolomics-Based Biomarker for Heart Failure with Reduced Ejection Fraction

Friday, January 30 | 4:00PM - 4:30PM
Coffee Available
Room: Sweeney Ballroom Foyer


Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
Room: Sweeney Ballroom C-E

Speaker 1 of 6
* Qiangrong Liang, New York Institute of Technology, College of Osteopathic Medicine, USA

Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
Room: Sweeney Ballroom C-E

Speaker 2 of 6
Paolo Bernardi, University of Padova Medical School, Italy
The Mitochondrial Permeability Transition Pore

Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
Room: Sweeney Ballroom C-E

Speaker 3 of 6
Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
New Model of Mitochondrial Permeability Transition Pore (MPTP) Formation and Regulated Necrosis in the Heart

Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
Room: Sweeney Ballroom C-E

Speaker 4 of 6
Kinya Otsu, UK
Mitochondria, Cell Death and Inflammation

Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
Room: Sweeney Ballroom C-E

Speaker 5 of 6
Wendy M. McKimpson, Columbia University, USA
The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote Beta-Cell Survival in Diabetes

Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
Room: Sweeney Ballroom C-E

Speaker 6 of 6
Maik Hüttemann, Wayne State University, USA
Short Talk: Regulation of Mitochondrial Respiration and Apoptosis by Cytochrome c Phosphorylation

Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 1 of 6
* C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA


Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 2 of 6
Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Discovery of a Novel Class of Naturally-Occurring Lipids with Anti-Diabetic and Anti-Inflammatory Effects


Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 3 of 6
Michael P. Czech, University of Massachusetts Medical School, USA
Adipose Lipogenesis in Control of Glucose Tolerance


Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 4 of 6
Catherine Postic, INSERM Institut Cochin, France
ChREBP and Liver Steatosis


Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 5 of 6
Alan R. Saltiel, University of California, San Diego, USA
Energy Expenditure Mediated by the Non-Canonical IKB Kinases


Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 6 of 6
Praveen Sethupathy, Cornell University, USA
Short Talk: MicroRNA-Mediated Control of Metabolic Homeostasis


Friday, January 30 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts
No registration fees are used to fund alcohol served at this function.

Friday, January 30 | 7:30PM - 10:00PM
Poster Session 3
Room: Sweeney F, Main Level Breakouts


Saturday, January 31 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 6
* Deborah M. Muoio, Duke University Medical Center, USA

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 6
David A. Sinclair, Harvard Medical School, USA
Coupling Nuclear and Mitochondrial Transcription

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 6
Douglas C. Wallace, Children's Hospital of Philadelphia, USA
Mitochondrial Mutations and Human Disease

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 6
Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland
Mitochondrial Function, Metabolism and Aging


Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 6
Heidi M. McBride, McGill University, Canada
Redox Control of Mitochondrial Plasticity, Uncovering New Mechanisms that Link Function to Form

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 6
Peter S. Rabinovitch, University of Washington, USA
Short Talk: Short-Term Treatment with Mitochondrial Protective Peptide SS-31 Reverses Cardiac Aging in Mice

Saturday, January 31 | 9:20AM - 9:40AM
Coffee Break
Room: Sweeney Ballroom Foyer


Saturday, January 31 | 11:00AM - 4:30PM
On Own for Lunch


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 1 of 9
* Jeffrey E. Pessin, Albert Einstein College of Medicine, USA


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 2 of 9
Hyokjoon Kwon, Albert Einstein College of Medicine, USA
High Fat Diet-Induced Interleukin-13 Modulates Inflammation and Insulin Resistance


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 3 of 9
Yun Sok Lee, University of California, San Diego, USA
Saturated Fatty Acids Induce Uncoupled Mitochondrial Respiration and Trigger HIF-1alpha Causing Inflammation and Insulin Resistance in Obesity


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 4 of 9
Rubén García-Martín, Dresden University of Technology, Germany
Adipocyte Hypoxia-Inducible Factor 2 Protects from Whitening of the Brown Adipose Tissue and Metabolic Dysregulation in the Course of Diet-Induced Obesity


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 5 of 9
Sagar P. Bapat, University of California, San Francisco, USA
Fat Regulatory T Cells Drive Age-Associated Insulin Resistance


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 6 of 9
Prameladevi Chinnasamy, Einstein College of Medicine, Montefiore Medical Center, USA
Allograft Inflammatory Factor-1 in Obesity and Type II Diabetes


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 7 of 9
Caroline Tao, Amgen, USA
Dichotomous Role of Adipocyte Toll-Like Receptor 4 on Insulin Sensitivity


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 8 of 9
Sojin Lee, University of Pittsburgh School of Medicine, Children's Hosp of Pittsburgh, USA
FoxO1 Dictates M1 vs. M2 Polarization and Integrates Inflammation to Insulin Resistance in Diabetes


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 9 of 9
Hye Eun Lee, Catholic University of Korea, South Korea
Suppression of NLRP3 Inflammasome Activation by Caffeic Acid Phenethyl Ester and its Significance in Modulation of Metabolic Diseases


Saturday, January 31 | 4:00PM - 4:30PM
Coffee Available
Room: Sweeney Ballroom Foyer


Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
Room: Sweeney Ballroom C-E

Speaker 1 of 4
* Maha Abdellatif, University of Medicine & Dentistry of New Jersey, USA

Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
Room: Sweeney Ballroom C-E

Speaker 2 of 4
Ira J. Goldberg, New York University, USA
Lipid Uptake, the Route to Lipid Droplet Formation and Cardiomyocyte Toxicity

Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
Room: Sweeney Ballroom C-E

Speaker 3 of 4
Kenneth Walsh, University of Virginia School of Medicine, USA
Molecular Links between Metabolic and Cardiovascular Diseases

Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
Room: Sweeney Ballroom C-E

Speaker 4 of 4
Lorrie A. Kirshenbaum, University of Manitoba, Canada
Bnip3 Mediated Loss of Mitochondrial UCP3-Cytochrome c Oxidase Complexes Underlies Respiratory Defects and Cardiac Failure in Anthracycline Cardiotoxicity

Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 1 of 5
* Michael P. Czech, University of Massachusetts Medical School, USA


Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 2 of 5
Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA
Integrating Metabolism Around the Clock


Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 3 of 5
Joseph T. Bass, Northwestern University, USA
Circadian Control of Metabolic Signaling


Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 4 of 5
Ueli Schibler, University of Geneva, Switzerland
Systemic Regulation of Circadian Gene Expression


Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
This session is from Diabetes/Metabolic Dysfunction
Room: Sweeney Ballroom A-B

Speaker 5 of 5
Jorge L. Ruas, Karolinska Institutet, Sweden
Short Talk: A Molecular Mechanism for Skeletal Muscle - Brain Crosstalk that Protects from Stress-Induced Depression


Saturday, January 31 | 6:30PM - 7:30PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts
No registration fees are used to fund alcohol served at this function.

Saturday, January 31 | 7:30PM - 11:00PM
Cash Bar
Room: Sweeney F, Main Level Breakouts


Saturday, January 31 | 8:00PM - 11:00PM
Entertainment
Room: Sweeney F, Main Level Breakouts
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Sunday, February 01 | 10:25AM - 10:25AM
Departure


*Session Chair.