Web Desc
Diabetes and Metabolic Dysfunction
joint with Mitochondria, Metabolism and Heart Failure
Organizer(s): Jeffrey E. Pessin, Alan R. Saltiel and Deborah M. Muoio
Date: January 27 - February 01, 2015
Location: Santa Fe Community Convention Center, Santa Fe, NM, USA
Sponsored by Intercept Pharmaceuticals, Inc., the Journal of Molecular Cell Biology (JMCB), MedImmune, Novo Nordisk A/S and Pfizer Inc. Supported by an educational donation provided by Amgen.
Summary of Meeting:
Diabetes and obesity-related complications and associated metabolic disorders are major public health problems at the local, national and global levels. These metabolic defects underlie the basis for multiple debilitating diseases including heart disease, stroke, blindness, kidney disease, hypertension, neural degeneration, wound healing, amputations, periodontal disease and birth defects. This meeting will address several cutting-edge aspects of molecular, cellular, tissue and integrative system metabolism that account for the metabolic defects that occur in diabetes and obesity. Several of these themes overlap with the concurrent meeting on Mitochondria, Metabolism and Heart Failure and four concurrent sessions are planned addressing distinct and novel aspects of normal and dysregulation muscle (skeletal and cardiac) intracellular signaling, mitochondria function/dynamics, aging and energy balance. Leaders in each of these respective areas will not only address basic and integrative mechanisms in model systems, but several will address these issues in human pathology. The diabetes-specific sessions reflect several key aspects of metabolic dysregulation in which novel information is currently forthcoming, causing a paradigm shift compared to our previous understanding of these processes. These include new information about tissue cross-talk, the inter-relationship between the control of glucose production and fatty acid synthesis that underlies selective insulin resistance and the role of normal and dysregulated circadian rhythms on metabolic processes. These cutting-edge advances will provide a foundation for identifying future research directions.
Scholarship Deadline: October 1 2014
Discounted Abstract Deadline: October 1 2014
Abstract Deadline: October 28 2014
Discounted Registration Deadline: November 25 2014
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Educational donation provided by AmgenIntercept Pharmaceuticals, Inc.Journal of Molecular Cell Biology (JMCB)MedImmuneNovo Nordisk A/SPfizer Inc.
We gratefully acknowledge additional support for this conference from:
Journal of Lipid Research
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
PLOS
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Grant No. 5R13DK104616-01
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Tuesday, January 27 | 4:00PM - 8:00PM
Arrival and Registration
Room: Sweeney Ballroom Foyer


Tuesday, January 27 | 6:00PM - 8:00PM
Welcome Mixer
Room: Sweeney F
No registration fees are used to fund alcohol served at this function.

Wednesday, January 28 | 7:00AM - 9:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 2:00PM - 3:00PM
Poster Setup
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 2:30PM - 3:00PM
Coffee Available
Room: Sweeney Ballroom Foyer


Wednesday, January 28 | 3:00PM - 10:00PM
Poster Viewing
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 3:00PM - 4:00PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 3
* Jeffrey E. Pessin, Albert Einstein College of Medicine, USA

Wednesday, January 28 | 3:00PM - 4:00PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 3
* Richard N. Kitsis, Albert Einstein College of Medicine, USA

Wednesday, January 28 | 3:00PM - 4:00PM
Welcome and Keynote Address (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 3
Helen H. Hobbs, University of Texas Southwestern Medical Center, USA
Journal of Lipid Research Lectureship Introduced by JLR Associate Editor, Ira Goldberg. Orchestrating Fatty Acid Flux to Adipose Tissue during Feast and Famine

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 5
* Rong Tian, University of Washington, USA

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 5
Christopher B. Newgard, Duke University Medical Center, USA
Role of the Gut Microbiota in the Pathogenesis and Treatment of Cardiometabolic Diseases

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 5
E. Dale Abel, University of Iowa, Carver College of Medicine, USA
Insulin Signaling in the Heart

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 5
Eric N. Olson, University of Texas Southwestern Medical Center, USA
Muscular 'Mediators' of Metabolism

Wednesday, January 28 | 4:00PM - 7:00PM
Regulation of Metabolism (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 5
Lawrence Kazak, McGill University, Canada
Regulation of Heat Production by Various Shades of Fat: A Novel Thermogenic Pathway in Beige Fat

Wednesday, January 28 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts


Wednesday, January 28 | 7:30PM - 10:00PM
Poster Session 1
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 7
* Heidi M. McBride, McGill University, Canada

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 7
Richard J. Youle, NINDS, National Institutes of Health, USA
Damage Control: How PINK1 and Parkin Survey Mitochondrial Fidelity and Respond with Selective Autophagy

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 7
Jennifer A. Lippincott-Schwartz, Howard Hughes Medical Institute - Janelia Farm, USA
Roles of Lipid Droplet Lipolysis, Autophagy and Mitochondrial Fusion Dynamics in Fatty Acid Trafficking within Cells

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 7
Orian S. Shirihai, University of California, Los Angeles, USA
Mitochondrial Dynamics and Quality Control, a Conflict of Interest

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 7
Gerald W. Dorn, II, Washington University School of Medicine, USA
Mitochondrial Dynamics, Mitochondrial Quality Control and Heart Disease

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 7
Luca Scorrano, University of Padova, Italy
Keeping Mitochondria Cristae in Shape to Control Organ Damage and Metabolism

Thursday, January 29 | 8:00AM - 12:00PM
Mitochondrial Quality Control (Joint)
Room: Sweeney Ballroom A-E

Speaker 7 of 7
Peipei Ping, University of California, Los Angeles, USA
Data Science Approaches for Mitochondrial Discoveries

Thursday, January 29 | 9:50AM - 10:10AM
Coffee Break
Room: Sweeney Ballroom Foyer


Thursday, January 29 | 12:00PM - 1:00PM
Poster Setup
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 12:00PM - 4:30PM
On Own for Lunch


Thursday, January 29 | 1:00PM - 10:00PM
Poster Viewing
Room: Sweeney F, Main Level Breakouts


Thursday, January 29 | 4:00PM - 4:30PM
Coffee Available
Room: Sweeney Ballroom Foyer


Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 1 of 7
* Alan R. Saltiel, University of California, San Diego, USA

Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 2 of 7
Deborah M. Muoio, Duke University Medical Center, USA
Nutrient-Induced Mitochondrial Stress and Metabolic Inflexibility in Skeletal Muscle



Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 3 of 7
Morris J. Birnbaum, Uninversity of Pennsylvania and Pfizer, Inc, USA
Non-Autonomous Regulation of Hepatic Glucose Output by Insulin

Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 4 of 7
Domenico Accili, Columbia University, USA
FOXO Signaling and Hepatic Glucose Production

Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 5 of 7
Marc R. Montminy, The Salk Institute for Biological Studies, USA
Regulation of Hepatic Gluconeogenesis by the CREB Pathway

Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 6 of 7
Carl S. Thummel, University of Utah School of Medicine, USA
Short Talk: The Molecular Basis of MODY1 and its Regulation by HNF4

Thursday, January 29 | 4:30PM - 7:20PM
Mechanisms of Dysregulated Glucogenogenesis
Room: Sweeney Ballroom A-B

Speaker 7 of 7
Alexander S. Banks, Harvard Medical School, USA
Short Talk: Therapeutic Resolution of Insulin Resistance via MEK/ERK Inhibition and Reversal of PPARgamma Serine 273 Phosphorylation

Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 1 of 6
* Sihem Boudina, University of Utah School of Medicine, USA


Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 2 of 6
Rong Tian, University of Washington, USA
Metabolic Remodeling of the Heart


Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 3 of 6
E. Douglas Lewandowski, University of Illinois at Chicago College of Medicine, USA
Remodeled Metabolism In and Around the Failing Heart


Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 4 of 6
Daniel P. Kelly, University of Pennsylvania, USA
Deciphering the Metabolic Basis of Heart Failure


Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 5 of 6
Edward T. Chouchani, Dana-Farber Cancer Institute, USA
Short Talk: Ischemic Accumulation of Succinate Controls Reperfusion Injury through Mitochondrial ROS


Thursday, January 29 | 4:30PM - 7:00PM
Metabolism Under Stress in Heart Disease and Diabetes
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 6 of 6
Benjamin A. Olenchock, Brigham and Women’s Hospital, USA
Short Talk: Inhibition of the Prolyl Hydroxylase EglN1 Is Sufficient for Local and Remote Cardiac Ischemic Protection: Role of Tryptophan Metabolism


Thursday, January 29 | 7:05PM - 8:05PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts
No registration fees are used to fund alcohol served at this function.

Thursday, January 29 | 7:30PM - 10:00PM
Poster Session 2
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
Room: Sweeney Ballroom A-B

Speaker 1 of 6
* Christopher B. Newgard, Duke University Medical Center, USA

Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
Room: Sweeney Ballroom A-B

Speaker 2 of 6
Ronald M. Evans, HHMI/The Salk Institute, USA
Nuclear Receptors and the Hunger Game: From Feast to Famine

Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
Room: Sweeney Ballroom A-B

Speaker 3 of 6
John F. Rawls, Duke University, USA
Microbial Regulation of Intestinal Lipid Metabolism and Gene Expression

Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
Room: Sweeney Ballroom A-B

Speaker 4 of 6
C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA
New Insights into Insulin Signaling and Insulin Action in Muscle through Genetic Manipulation

Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
Room: Sweeney Ballroom A-B

Speaker 5 of 6
Gökhan S. Hotamisligil, Harvard School of Public Health, USA
Endoplasmic Reticulum and Mitochondria Integration in Response to Metabolic Stress

Friday, January 30 | 8:00AM - 11:20AM
Emerging Synergy between Metabolism and the Gut Microbiome
Room: Sweeney Ballroom A-B

Speaker 6 of 6
Gerard Karsenty, Columbia University Medical Center, USA
A Crosstalk between Glucose Uptake and Runx2 Determines the Onset of Osteoblast Differentiation and the Extent of Bone Formation

Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 1 of 8
* Konstantinos Drosatos, Temple University School of Medicine, USA


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 2 of 8
Roberta A. Gottlieb, Cedars-Sinai Medical Center, USA
Autophagy in Cardioprotection and Impact of Metabolic Syndrome


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 3 of 8
Åsa B. Gustafsson, University of California, San Diego, USA
MCL-1 as a Critical Regulator of Mitochondrial Function and Cell Death


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 4 of 8
Elizabeth Murphy, Cardiac Physiology Section Vascular Medicine Branch, NHLBI, NIH, USA
Calcium Regulation of Mitochondrial Function


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 5 of 8
Junichi Sadoshima, Rutgers New Jersey Medical School, USA
Ulk1 Plays a Crucial Role in Mitochondrial Autophagy in Cardiomyocytes


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 6 of 8
Christoph Maack, Universitätsklinikum des Saarlandes, Germany
Impact of the Mitochondrial/SR Interaction for Redox Regulation


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 7 of 8
Saptarsi M. Haldar, University of California, San Francisco, USA
Short Talk: Glucocorticoids Elicit Ergogenic Effects in Muscle via a Defined Transcriptional Pathway


Friday, January 30 | 8:00AM - 11:50AM
Cardiac Autophagy
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 8 of 8
Anja Karlstaedt, University of Texas Medical School at Houston, USA
Short Talk: Regulation of mTOR Activation during Acute Increases of Heart Work: The Role of Endogenous Substrates


Friday, January 30 | 9:40AM - 10:00AM
Coffee Break
Room: Sweeney Ballroom Foyer


Friday, January 30 | 11:20AM - 1:00PM
Poster Setup
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 11:20AM - 4:30PM
On Own for Lunch


Friday, January 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Sweeney F, Main Level Breakouts


Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 1 of 9
* Jeffrey E. Pessin, Albert Einstein College of Medicine, USA

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 2 of 9
Ronald N. Margolis, NIDDK, National Institutes of Health, USA
Biomedical Big Data: Data Discovery and the Digital Enterprise

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 3 of 9
Abdelilah Arredouani, Qatar Foundation, Qatar
Non-Targeted Metabolomic Profiling Score Improves the Early Prediction of Type 2 Diabetes in the Prospective D.E.S.I.R. Study

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 4 of 9
Ida Donkin, Copenhagen University, Denmark
Spermatozoa from Lean and Obese Humans Carry Distinct Epigenetic Signatures

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 5 of 9
Olga Gupta, University of Texas Southwestern Medical Center, USA
Transcriptome Profiling of Omental Adipose Mesothelial Cells Reveals Differentially Expressed Transcripts Related to Inflammation

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 6 of 9
Ondrej Kuda, Academy of Sciences of the Czech Republic, Czech Republic
Metabolipidomical Profiling of Adipose Tissue during Fatty Acid Re-Esterification

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 7 of 9
Xiaofeng Xin, Massachusetts Institute of Technology, USA
Systems Biology of Obesity-Induced Hepatic Insulin Resistance

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 8 of 9
Adam R. Wende, University of Alabama at Birmingham, USA
DNA Methylation and Corresponding Gene Expression Changes in the Diabetic Heart

Friday, January 30 | 2:30PM - 4:30PM
Workshop: Big Data to Knowledge (BD2K) (Joint)
Room: Sweeney Ballroom C-E

Speaker 9 of 9
Dietrich Rein, Metanomics Health, Germany
Validation of a Metabolomics-Based Biomarker for Heart Failure with Reduced Ejection Fraction

Friday, January 30 | 4:00PM - 4:30PM
Coffee Available
Room: Sweeney Ballroom Foyer


Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
Room: Sweeney Ballroom A-B

Speaker 1 of 6
* C. Ronald Kahn, Joslin Diabetes Center and Harvard Medical School, USA

Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
Room: Sweeney Ballroom A-B

Speaker 2 of 6
Barbara B. Kahn, Beth Israel Deaconess Medical Center, Harvard Medical School, USA
Discovery of a Novel Class of Naturally-Occurring Lipids with Anti-Diabetic and Anti-Inflammatory Effects

Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
Room: Sweeney Ballroom A-B

Speaker 3 of 6
Michael P. Czech, University of Massachusetts Medical School, USA
Adipose Lipogenesis in Control of Glucose Tolerance

Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
Room: Sweeney Ballroom A-B

Speaker 4 of 6
Catherine Postic, INSERM Institut Cochin, France
ChREBP and Liver Steatosis

Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
Room: Sweeney Ballroom A-B

Speaker 5 of 6
Alan R. Saltiel, University of California, San Diego, USA
Energy Expenditure Mediated by the Non-Canonical IKB Kinases

Friday, January 30 | 4:30PM - 7:05PM
Mechanisms of Dysregulated Lipogenesis
Room: Sweeney Ballroom A-B

Speaker 6 of 6
Praveen Sethupathy, Cornell University, USA
Short Talk: MicroRNA-Mediated Control of Metabolic Homeostasis

Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 1 of 6
* Qiangrong Liang, New York Institute of Technology, College of Osteopathic Medicine, USA


Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 2 of 6
Paolo Bernardi, University of Padova Medical School, Italy
The Mitochondrial Permeability Transition Pore


Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 3 of 6
Jeffery D. Molkentin, Cincinnati Children's Hospital Medical Center, USA
New Model of Mitochondrial Permeability Transition Pore (MPTP) Formation and Regulated Necrosis in the Heart


Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 4 of 6
Kinya Otsu, UK
Mitochondria, Cell Death and Inflammation


Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 5 of 6
Wendy M. McKimpson, Columbia University, USA
The Apoptosis Inhibitor ARC Alleviates the ER Stress Response to Promote Beta-Cell Survival in Diabetes


Friday, January 30 | 4:30PM - 7:00PM
Mitochondria and Endoplasmic Reticulum-Mediated Cell Death
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 6 of 6
Maik Hüttemann, Wayne State University, USA
Short Talk: Regulation of Mitochondrial Respiration and Apoptosis by Cytochrome c Phosphorylation


Friday, January 30 | 7:05PM - 8:05PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts
No registration fees are used to fund alcohol served at this function.

Friday, January 30 | 7:30PM - 10:00PM
Poster Session 3
Room: Sweeney F, Main Level Breakouts


Saturday, January 31 | 7:00AM - 8:00AM
Breakfast
Room: Sweeney F, Main Level Breakouts


Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 1 of 6
* Deborah M. Muoio, Duke University Medical Center, USA

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 2 of 6
David A. Sinclair, Harvard Medical School, USA
Coupling Nuclear and Mitochondrial Transcription

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 3 of 6
Douglas C. Wallace, Children's Hospital of Philadelphia, USA
Mitochondrial Mutations and Human Disease

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 4 of 6
Johan Auwerx, École Polytechnique Fédérale de Lausanne, Switzerland
Mitochondrial Function, Metabolism and Aging


Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 5 of 6
Heidi M. McBride, McGill University, Canada
Redox Control of Mitochondrial Plasticity, Uncovering New Mechanisms that Link Function to Form

Saturday, January 31 | 8:00AM - 11:00AM
Mitochondria, Metabolism and Aging (Joint)
Room: Sweeney Ballroom A-E

Speaker 6 of 6
Peter S. Rabinovitch, University of Washington, USA
Short Talk: Short-Term Treatment with Mitochondrial Protective Peptide SS-31 Reverses Cardiac Aging in Mice

Saturday, January 31 | 9:20AM - 9:40AM
Coffee Break
Room: Sweeney Ballroom Foyer


Saturday, January 31 | 11:00AM - 4:30PM
On Own for Lunch


Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 1 of 9
* Jeffrey E. Pessin, Albert Einstein College of Medicine, USA

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 2 of 9
Hyokjoon Kwon, Albert Einstein College of Medicine, USA
High Fat Diet-Induced Interleukin-13 Modulates Inflammation and Insulin Resistance

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 3 of 9
Yun Sok Lee, University of California, San Diego, USA
Saturated Fatty Acids Induce Uncoupled Mitochondrial Respiration and Trigger HIF-1alpha Causing Inflammation and Insulin Resistance in Obesity

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 4 of 9
Rubén García-Martín, Dresden University of Technology, Germany
Adipocyte Hypoxia-Inducible Factor 2 Protects from Whitening of the Brown Adipose Tissue and Metabolic Dysregulation in the Course of Diet-Induced Obesity

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 5 of 9
Sagar P. Bapat, University of California, San Francisco, USA
Fat Regulatory T Cells Drive Age-Associated Insulin Resistance

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 6 of 9
Prameladevi Chinnasamy, Einstein College of Medicine, Montefiore Medical Center, USA
Allograft Inflammatory Factor-1 in Obesity and Type II Diabetes

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 7 of 9
Caroline Tao, Amgen, USA
Dichotomous Role of Adipocyte Toll-Like Receptor 4 on Insulin Sensitivity

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 8 of 9
Sojin Lee, University of Pittsburgh School of Medicine, Children's Hosp of Pittsburgh, USA
FoxO1 Dictates M1 vs. M2 Polarization and Integrates Inflammation to Insulin Resistance in Diabetes

Saturday, January 31 | 2:00PM - 4:00PM
Workshop: Inflammation in Diabetes, Obesity and Insulin Resi
stance
Room: Sweeney Ballroom A-B

Speaker 9 of 9
Hye Eun Lee, Catholic University of Korea, South Korea
Suppression of NLRP3 Inflammasome Activation by Caffeic Acid Phenethyl Ester and its Significance in Modulation of Metabolic Diseases

Saturday, January 31 | 4:00PM - 4:30PM
Coffee Available
Room: Sweeney Ballroom Foyer


Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
Room: Sweeney Ballroom A-B

Speaker 1 of 5
* Michael P. Czech, University of Massachusetts Medical School, USA

Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
Room: Sweeney Ballroom A-B

Speaker 2 of 5
Mitchell A. Lazar, Perelman School of Medicine, University of Pennsylvania, USA
Integrating Metabolism Around the Clock

Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
Room: Sweeney Ballroom A-B

Speaker 3 of 5
Joseph T. Bass, Northwestern University, USA
Circadian Control of Metabolic Signaling

Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
Room: Sweeney Ballroom A-B

Speaker 4 of 5
Ueli Schibler, University of Geneva, Switzerland
Systemic Regulation of Circadian Gene Expression

Saturday, January 31 | 4:30PM - 6:45PM
Circadian Rhythms in Metabolic Networks
Room: Sweeney Ballroom A-B

Speaker 5 of 5
Jorge L. Ruas, Karolinska Institutet, Sweden
Short Talk: A Molecular Mechanism for Skeletal Muscle - Brain Crosstalk that Protects from Stress-Induced Depression

Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 1 of 4
* Maha Abdellatif, University of Medicine & Dentistry of New Jersey, USA


Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 2 of 4
Ira J. Goldberg, New York University, USA
Lipid Uptake, the Route to Lipid Droplet Formation and Cardiomyocyte Toxicity


Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 3 of 4
Kenneth Walsh, University of Virginia School of Medicine, USA
Molecular Links between Metabolic and Cardiovascular Diseases


Saturday, January 31 | 4:30PM - 6:30PM
Toxins and Protectors of the Myocardium
This session is from Mitochondria
Room: Sweeney Ballroom C-E

Speaker 4 of 4
Lorrie A. Kirshenbaum, University of Manitoba, Canada
Bnip3 Mediated Loss of Mitochondrial UCP3-Cytochrome c Oxidase Complexes Underlies Respiratory Defects and Cardiac Failure in Anthracycline Cardiotoxicity


Saturday, January 31 | 6:45PM - 7:45PM
Social Hour with Lite Bites
Room: Sweeney F, Main Level Breakouts
No registration fees are used to fund alcohol served at this function.

Saturday, January 31 | 7:45PM - 11:00PM
Cash Bar
Room: Sweeney F, Main Level Breakouts


Saturday, January 31 | 8:00PM - 11:00PM
Entertainment
Room: Sweeney F, Main Level Breakouts
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Sunday, February 01 | 10:25AM - 10:25AM
Departure


*Session Chair.