Web Desc
DNA Methylation
joint with Epigenomics
Organizer(s): Alexander Meissner and Dirk Schübeler
Date: March 29 - April 03, 2015
Location: Keystone Resort, Keystone, CO, USA
Supported by the Directors' Fund
Summary of Meeting:
DNA methylation is essential for mammalian development and plays an important regulatory role in many organisms including plants. Major advances have been made in functionally studying the key players involved in establishing and maintaining DNA methylation as well as mapping its genome-wide location. Many gaps remain toward a complete understanding in particular in diseases. In this meeting experts in the field provide the latest insights from plants to mammalian development. A further focus is the relevance of DNA methylation for cancer biology and how it may lead to more advanced diagnostics and treatments in the clinic.
Scholarship Deadline: December 3 2014
Discounted Abstract Deadline: December 3 2014
Abstract Deadline: January 8 2015
Discounted Registration Deadline: January 29 2015
We gratefully acknowledge additional support for this conference from:
TriLink BiotechnologiesZymo Research Corporation
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

New England Biolabs, Inc.
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Environmental Health Sciences (NIEHS)
Grant No. 1R13ES025502-01
Funding for this conference was made possible (in part) by 1R13ES025502-01 from the NIH Common Fund and the National Institute of Environmental Health Sciences. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 29 | 4:00PM - 8:00PM
Arrival and Registration
Room: Longs Peak Foyer


Sunday, March 29 | 6:00PM - 8:00PM
Welcome Mixer
Room: Longs Peak Foyer
No registration fees are used to fund alcohol served at this function.

Monday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Monday, March 30 | 8:00AM - 9:00AM
Keynote Address (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 2
* Daniel Zilberman, University of California, Berkeley, USA

Monday, March 30 | 8:00AM - 9:00AM
Keynote Address (Joint)
Room: Longs/Grays Peaks

Speaker 2 of 2
Adrian P. Bird, University of Edinburgh, UK
DNA Methylation and Other CpG Signaling

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 6
* Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research, Switzerland

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 2 of 6
Alexander Meissner, Max Planck Institute for Molecular Genetics, Germany
DNA Methylation Dynamics in Development and Disease

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 3 of 6
Steven E. Jacobsen, University of California, Los Angeles, USA
DNA Methylation in Flowering Plants

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 4 of 6
Ryan Lister, University of Western Australia, Australia
Short Talk: Large-Scale Interrogation of the Repressive Capacity of Human Promoter DNA Methylation by Genome-Wide Epigenomic Manipulation

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 5 of 6
Bradley R. Cairns, HHMI/University of Utah, USA
Chromatin-Transcription Dynamics in Developing Germline Stem Cells

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 6 of 6
Marie Classon, USA
Short Talk: A Heterochromatic State Required for the Survival of Drug-Tolerant Cancer Cell Populations

Monday, March 30 | 9:40AM - 10:00AM
Coffee Break
Room: Longs Peak Foyer


Monday, March 30 | 11:30AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Monday, March 30 | 11:30AM - 5:00PM
On Own for Lunch


Monday, March 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Roadmap Epigenomic Tutorial
This session is from Epigenomics
Room: Longs/Grays Peaks
Designed to highlight resources generated by the NIH Roadmap Epigenomic Project and related international human epigenome projects from 10 countries. Speakers include investigators currently participating in these large-scale projects.
Speaker 1 of 1
* Ting Wang, Washington University, USA


Monday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
Room: Quandary Peak

Speaker 1 of 6
* Anne C. Ferguson-Smith, University of Cambridge, UK

Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
Room: Quandary Peak

Speaker 2 of 6
Wolf Reik, Babraham Institute, UK
Epigenetic Reprogramming in Mammalian Development

Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
Room: Quandary Peak

Speaker 3 of 6
Matthew C. Lorincz, University of British Columbia, Canada
Impact of LTR Retrotransposons on the Transcriptome and Methylome in the Mouse Germline

Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
Room: Quandary Peak

Speaker 4 of 6
Jonathan I. Gent, University of Georgia, USA
Short Talk: RNA-Directed DNA Methylation in Suppression of Intronic Transposons: Minimizing Collateral Damage on Host Gene Expression

Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
Room: Quandary Peak

Speaker 5 of 6
Marius Walter, Institut Curie, France
Short Talk: Transposon Regulation upon Acute Loss of DNA Methylation

Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
Room: Quandary Peak

Speaker 6 of 6
Vincent Colot, École Normale Supérieure, France
Molecular and Developmental Basis of Progressive DNA Methylation across Generations

Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 6
* Barbara J. Meyer, University of California, Berkeley, USA


Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 2 of 6
Steven Henikoff, Fred Hutchinson Cancer Research Center, USA
Nucleosome Barriers to Transcription


Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 3 of 6
Alicia N. Schep, Stanford University, USA
Short Talk: NucleoATAC: Structured ATAC-seq Signal Around Nucleosomes Enables High-Resolution Nucleosome Positioning


Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 4 of 6
B. Franklin Pugh, Pennsylvania State University, USA
Genome-Wide Organization of Chromatin


Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 5 of 6
Jeffrey N. McKnight, Fred Hutchinson Cancer Research Center, USA
Short Talk: Global Relocalization of the Rpd3 Histone Deacetylase Drives Quiescence Entry in S. cerevisiae


Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 6 of 6
Jason D. Lieb, University of Chicago, USA
Evidence for Lamin A Function at Enhancers, with Implications for Hutchinson-Gilford Progeria


Monday, March 30 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, March 30 | 7:30PM - 10:00PM
Poster Session 1
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 1 of 8
* Margaret A. Goodell, Baylor College of Medicine, USA

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 2 of 8
Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA
FBXL10 Defends Polycomb-Bound Genes Against Hypermethylation

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 3 of 8
Xiaodong Cheng, Emory University, USA
Generation, Recognition and Erasure (GRE) of 5-Methylcytosine and its Oxidative Derivatives

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 4 of 8
Sriharsa Pradhan, New England Biolabs, USA
Regulation of DNMT1 Stability and Activity by Reader, Writer, Eraser and MicroRNA

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 5 of 8
Jiahao Huang, Babraham Institute, UK
Short Talk: Histone Modifiers Maintain Fidelity of de novo DNA Methylation in Growing Oocytes

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 6 of 8
Jafar Sharif, RIKEN IMS, Japan
Short Talk: Protracted NP95 Binding to Hemimethylated DNA Disrupts SETDB1-Mediated Proviral Silencing

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 7 of 8
Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Genome Reprogramming by Histone Variants and Small RNA

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
Room: Quandary Peak

Speaker 8 of 8
Manu J. Dubin, Gregor Mendel Institute, Austria
Short Talk: DNA Methylation Variation in Arabidopsis Has a Genetic Basis and Shows Evidence of Local Adaptation

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 7
* Bas van Steensel, Netherlands Cancer Institute, Netherlands


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 2 of 7
Barbara J. Meyer, University of California, Berkeley, USA
Condensin-Driven Remodeling of X-Chromosome Topology during Dosage Compensation


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 3 of 7
Elphège P. Nora, University of California San Francisco, USA
Short Talk: Life without CTCF (at Least for a Short While)


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 4 of 7
Sarah Elderkin, Babraham Institute, UK
Short Talk: Polycomb Repressive Complex PRC1 Spatially Constrains the Mouse Embryonic Stem Cell Genome to Regulate Pluripotency


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 5 of 7
Iestyn Whitehouse, Memorial Sloan Kettering Cancer Center, USA
Chromatin Assembly: A View from the Lagging Strand


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 6 of 7
Natasha E. Weiser, University of Michigan, USA
Short Talk: MORC-1 Regulates Endogenous Small RNAs, Chromatin Organization and Germline Immortality


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 7 of 7
Manolis Kellis, Massachusetts Institute of Technology, Broad Institute, USA
Interplay between Chromatin State, Regulator Binding and Regulatory Motifs


Tuesday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 31 | 11:30AM - 5:00PM
On Own for Lunch


Tuesday, March 31 | 11:45AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
Room: Quandary Peak

Speaker 1 of 6
* Matthew C. Lorincz, University of British Columbia, Canada

Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
Room: Quandary Peak

Speaker 2 of 6
Joseph F. Costello, University of California, San Francisco, USA
The Function of Intermediate DNA Methylation

Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
Room: Quandary Peak

Speaker 3 of 6
Wenfeng An, South Dakota State University, USA
Short Talk: Retrotransposing Single-Copy Sequences into the Mouse Genome Reveals Sloping Shores: A Graded Influence of Hypomethylated CpG Islands on Flanking CpG Sites

Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
Room: Quandary Peak

Speaker 4 of 6
Marisa S. Bartolomei, University of Pennsylvania Perelman School of Medicine, USA
Insulators, CTCF and DNA Methylation in Imprinted Gene Clusters

Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
Room: Quandary Peak

Speaker 5 of 6
Anne C. Ferguson-Smith, University of Cambridge, UK
Genomic Imprinting and Parental-Origin Effects

Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
Room: Quandary Peak

Speaker 6 of 6
Claude Becker, Max Planck Institute for Developmental Biology, Germany
Short Talk: Maternal Transmission of Increased Salt Stress Tolerance in Arabidopsis Is Linked to DNA Methylation

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 7
* Manolis Kellis, Massachusetts Institute of Technology, Broad Institute, USA


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 2 of 7
Joanna Wysocka, Stanford University, USA
Retroelement Reactivation in Human Preimplantation Development


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 3 of 7
Christopher W. Ng, Massachusetts Institute of Technology, USA
Short Talk: Epigenetic Ensembles Presage Transcriptional Changes in Differentiation and Disease


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 4 of 7
Karine G. Le Roch, University of California, Riverside, USA
Short Talk: Association between Chromatin Structure, Gene Regulation and Pathogenicity in the Human Malaria Parasite, Plasmodium falciparum


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 5 of 7
Andrew Dimond, Babraham Institute, UK
Short Talk: Developmental Gene Promoters Establish Poised Enhancer Contacts in Embryonic Stem Cells


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 6 of 7
Jeremie F. Poschmann, Genome Institute of Singapore, Singapore
Short Talk: Large-Scale Mapping of Chromatin-Altering Polymorphisms Reveals Molecular Drivers of Human Disease


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 7 of 7
John A. Stamatoyannopoulos, Altius Institute for Biomedical Sciences, USA
Encoding Epigenesis


Tuesday, March 31 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, March 31 | 7:30PM - 10:00PM
Poster Session 2
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 1 of 7
Margaret A. Goodell, Baylor College of Medicine, USA
DNMT3A in Normal and Malignant Hematopoiesis

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 2 of 7
Peter A. Jones, Van Andel Research Institute, USA
Cancer Therapy

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 3 of 7
Benjamin Leadem, NIDDK, National Institutes of Health, USA
Short Talk: Novel Inhibitors of KDM5 Family Proteins Synergize with DNMT Inhibitors to Regulate Gene Expression and Inhibit Proliferation of Breast Cancer Cells

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 4 of 7
Jeanne F. Loring, The Scripps Research Institute, USA
Dynamics of DNA Methylation in Human Pluripotent Stem Cell Differentiation

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 5 of 7
Ralf Gilsbach, University of Freiburg, Germany
Short Talk: Stage-Specific Gene Expression Programs in Cardiomyocytes Rely on Dynamic CpG-Methylation or Polycomb Repressive Marks

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 6 of 7
Amos Tanay, Weizmann Institute, Israel
Single-Cell Transcriptional and Epigenomic Approaches to Complex Cell Populations

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
Room: Quandary Peak

Speaker 7 of 7
Yvette A. Luyten, New England Biolabs, USA
Short Talk: Bacterial DNA Methyltransferases: A New “Class” of Type I Restriction Modification Enzymes Utilizing Two Distinct DNA Methyltransferase Genes

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 7
* Erez Lieberman-Aiden, Baylor College of Medicine, USA


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 2 of 7
Noam Kaplan, University of Massachusetts Medical School, USA
How the 1D Genome Encodes 3D Topologically Associating Domains


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 3 of 7
Edith Heard, European Molecular Biology Laboratory, Germany
The Dynamics of X-Chromosome Structure and Activity during X Inactivation


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 4 of 7
Suhas S.P. Rao, Baylor College of Medicine, USA
Short Talk: Extremely High-Resolution 3D Maps of Human and Mouse Genomes Across Lineages and during Differentiation Reveal Principles of Chromatin Looping


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 5 of 7
Bas van Steensel, Netherlands Cancer Institute, Netherlands
Mapping Genome – Nuclear Lamina Interactions in Single Cells


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 6 of 7
Peter Fraser, Florida State University, USA
Single Molecule Analyses of Chromosome Folding and Genome Organization by Single-Cell Hi-C


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 7 of 7
Robert A. Beagrie, MRC Clinical Sciences Centre, UK
Short Talk: Novel, Ligation-Free Method for Identifying Chromatin Interactions Genome-Wide


Wednesday, April 01 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, April 01 | 11:30AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 11:30AM - 2:30PM
On Own for Lunch


Wednesday, April 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 1 of 7
* Amos Tanay, Weizmann Institute, Israel

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 2 of 7
* Remo Rohs, University of Southern California, USA
Modeling of the Effect of DNA Methylation on DNA Shape and Protein-DNA Binding

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 3 of 7
Michael M. Hoffman, University of Toronto, Canada
Transcription Factor Binding in an Expanded Epigenetic Alphabet

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 4 of 7
Önder Kartal, University of Zürich, Switzerland
An Information-Theoretic Approach to Discover Differential DNA Methylation in Plants Suggests that Diversity Is Highest in the CG Context

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 5 of 7
Fabian Müller, Stanford University, USA
Computational Methods for the DEEP Characterization of DNA Methylation BLUEPRINTs

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 6 of 7
Yaping Liu, Cincinnati Children's Hospital Medical Center, USA
meQTLFinder: A Bayesian Model to Detect meQTL by Using Chromatin States and Chromatin Interaction Prior Information

Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
Room: Quandary Peak

Speaker 7 of 7
David Gokhman, Hebrew University of Jerusalem, Israel
Paleo-Epigenetics: Reconstructing the DNA Methylation Maps of Archaic Hominins

Wednesday, April 01 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
Room: Quandary Peak

Speaker 1 of 6
* Peter A. Jones, Van Andel Research Institute, USA

Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
Room: Quandary Peak

Speaker 2 of 6
Stephan Beck, University College London, UK
Insights from Methylome Analysis

Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
Room: Quandary Peak

Speaker 3 of 6
Peter W. Laird, Van Andel Research Institute, USA
Cancer Methylomes

Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
Room: Quandary Peak

Speaker 4 of 6
Michiel Vermeulen, Radboud University, Netherlands
Quantitative Interaction Proteomics for Epigenetics

Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
Room: Quandary Peak

Speaker 5 of 6
Xueguang Sun, Zymo Research Corp, USA
Short Talk: Mirror Bisulfite Sequencing (Mirror-Seq): A Novel Sequencing Method for Genome-Wide Profiling of 5-Hydroxymethylcytosine with Single-Base Resolution

Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
Room: Quandary Peak

Speaker 6 of 6
Shinji Maegawa, Temple University, USA
Short Talk: DNA Methylation Drift as a Marker of Lifespan in Mammals

Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 6
* John L. Rinn, University of Colorado Boulder, USA


Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 2 of 6
Amy E. Pasquinelli, University of California, San Diego, USA
The Primary Target of let-7 MicroRNA


Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 3 of 6
Haifan Lin, Yale University, USA
Multifaceted Roles of the Piwi-piRNA Pathway in Gene Regulation


Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 4 of 6
Alla Grishok, Columbia University Medical Center, USA
Short Talk: Connecting Euchromatin and Endogenous RNAi in C. elegans


Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 5 of 6
Sam (Guoping) Gu, Rutgers University, USA
Short Talk: siRNA-Mediated Chromatin Regulation and Multigenerational Homeostasis of Germline Gene Expression in C. elegans


Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 6 of 6
Craig S. Pikaard, HHMI/Indiana University, USA
RNA Silencing and Epigenetic Inheritance


Wednesday, April 01 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, April 01 | 7:30PM - 10:00PM
Poster Session 3
Room: Colorado Rockies Ballroom


Thursday, April 02 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 7
* Alexander Meissner, Max Planck Institute for Molecular Genetics, Germany

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 2 of 7
Joseph R. Ecker, The Salk Institute for Biological Studies, USA
Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 3 of 7
Bing Ren, Ludwig Institute for Cancer Research, USA
Integrative Analysis of Haplotype-Resolved Epigenomes across Human Tissues

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 4 of 7
Daniel Zilberman, University of California, Berkeley, USA
Molecular Co-Evolution of Genomes and Chromatin

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 5 of 7
Andrew G. Clark, Cornell University, USA
Short Talk: Analysis of Novel Marsupial-Specific Imprinted Genes and their DMRs in the Opossum, Monodelphis domestica

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 6 of 7
Camila O. dos Santos, Cold Spring Harbor Laboratory, USA
Short Talk: An Epigenetic Memory of Pregnancy in the Mouse Mammary Gland

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 7 of 7
Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research, Switzerland
Sequence and Chromatin Determinants of DNA Methylation

Thursday, April 02 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Thursday, April 02 | 11:15AM - 5:00PM
On Own for Lunch


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 2: ENCODE Datasets Tutorial
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 1
* Feng Yue, Pennsylvania State University, USA


Thursday, April 02 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
Room: Quandary Peak

Speaker 1 of 4
* Xiaodong Cheng, Emory University, USA

Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
Room: Quandary Peak

Speaker 2 of 4
Frédéric L. Chedin, University of California, Davis, USA
Epigenomics Signatures of R-Loop Forming Regions

Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
Room: Quandary Peak

Speaker 3 of 4
Chuan He, University of Chicago, USA
Genome-Wide Sequencing of 5hmC and 5fC

Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
Room: Quandary Peak

Speaker 4 of 4
Salvatore Oliviero, Human Genetics Foundation, HuGeF, Italy
Short Talk: Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals DNA Methylation/Demethylation Dynamics in the Mammalian Genome

Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 1 of 6
* Amy E. Pasquinelli, University of California, San Diego, USA


Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 2 of 6
John L. Rinn, University of Colorado Boulder, USA
RNA-Binding Proteins Interact Specifically with Transposable Element Sequence in Human Genes


Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 3 of 6
Jindan Yu, Northwestern University Feinberg School of Medicine, USA
Short Talk: LncRNA HOTAIR Enhances the Androgen Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer


Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 4 of 6
L. Stirling Churchman, Harvard Medical School, USA
Short Talk: High-Resolution Architecture of Human Transcriptional Activity Revealed by Native Elongating Transcript Sequencing


Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 5 of 6
Gilad Fuchs, Weizmann Institute of Science, Israel
Short Talk: Cotranscriptional Histone H2B Monoubiquitylation Is Tightly Coupled with RNA Polymerase II Elongation Rate


Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
This session is from Epigenomics
Room: Longs/Grays Peaks

Speaker 6 of 6
Mitchell Guttman, California Institute of Technology, USA
lncRNAs: Function and Mechanism in Controlling Cellular Identity


Thursday, April 02 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Quandary Peak


Thursday, April 02 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from Epigenomics
Room: Longs/Grays Peak


Thursday, April 02 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, April 02 | 8:00PM - 11:00PM
Entertainment
Room: Colorado Rockies Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, April 02 | 8:00PM - 11:00PM
Cash Bar
Room: Colorado Rockies Ballroom


Friday, April 03 | 10:25AM - 10:25AM
Departure


*Session Chair.