Web Desc
Epigenomics
joint with DNA Methylation
Organizer(s): Bing Ren and Daniel Zilberman
Date: March 29 - April 03, 2015
Location: Keystone Resort, Keystone, CO, USA
Sponsored by Constellation Pharmaceuticals and Curemark LLC
Summary of Meeting:
Heritable, covalent modifications to DNA and histone proteins play an important role in an organism’s development and survival. Such epigenetic mechanisms have been increasingly linked to risks to a broad spectrum of human diseases. However, the exact function of epigenetic marks in development and disease pathogenesis remains to be better understood. With the help of recent technological advances in DNA sequencing technologies, epigenetic regulatory mechanisms have been investigated in a growing number of organisms at increasingly high resolution and scope. The results are an explosion in new genomic technologies, large-scale datasets and computational resources. The growing research field is now referred to as “epigenomics.” Epigenomics is still a young and growing field, and there are many challenges to investigators working on specific model organisms or disease who want to adopt this approach. This meeting is designed to capture the recent progress in the field in the same time bridge the technological gaps in the field, such as dataset availability, method adoption, data interpretation.
Scholarship Deadline: December 3 2014
Discounted Abstract Deadline: December 3 2014
Abstract Deadline: January 8 2015
Discounted Registration Deadline: January 29 2015
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Constellation PharmaceuticalsCuremark LLC
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
S. Karger A.G. - Medical Epigenetics
We gratefully acknowledge the generous grant for this conference provided by:

National Human Genome Research Institute (NHGRI)
Grant No. 1R13HG008333-01
Funding for this conference was made possible (in part) by 1 R13 HG 008333 - 01 from National Human Genome Research Institute (NHGRI) and the Office of the Director, National Institutes of Health (OD/NIH). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, March 29 | 4:00PM - 8:00PM
Arrival and Registration
Room: Longs Peak Foyer


Sunday, March 29 | 6:00PM - 8:00PM
Welcome Mixer
Room: Longs Peak Foyer
No registration fees are used to fund alcohol served at this function.

Monday, March 30 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Monday, March 30 | 8:00AM - 9:00AM
Keynote Address (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 2
* Daniel Zilberman, University of California, Berkeley, USA

Monday, March 30 | 8:00AM - 9:00AM
Keynote Address (Joint)
Room: Longs/Grays Peaks

Speaker 2 of 2
Adrian P. Bird, University of Edinburgh, UK
DNA Methylation and Other CpG Signaling

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 6
* Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research, Switzerland

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 2 of 6
Alexander Meissner, Max Planck Institute for Molecular Genetics, Germany
DNA Methylation Dynamics in Development and Disease

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 3 of 6
Steven E. Jacobsen, University of California, Los Angeles, USA
DNA Methylation in Flowering Plants

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 4 of 6
Ryan Lister, University of Western Australia, Australia
Short Talk: Large-Scale Interrogation of the Repressive Capacity of Human Promoter DNA Methylation by Genome-Wide Epigenomic Manipulation

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 5 of 6
Bradley R. Cairns, HHMI/University of Utah, USA
Chromatin-Transcription Dynamics in Developing Germline Stem Cells

Monday, March 30 | 9:00AM - 11:30AM
Genome-Wide DNA Methylation I (Joint)
Room: Longs/Grays Peaks

Speaker 6 of 6
Marie Classon, USA
Short Talk: A Heterochromatic State Required for the Survival of Drug-Tolerant Cancer Cell Populations

Monday, March 30 | 9:40AM - 10:00AM
Coffee Break
Room: Longs Peak Foyer


Monday, March 30 | 11:30AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Monday, March 30 | 11:30AM - 2:30PM
On Own for Lunch


Monday, March 30 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Monday, March 30 | 2:30PM - 4:30PM
Workshop 1: Roadmap Epigenomic Tutorial
Room: Longs/Grays Peaks
Designed to highlight resources generated by the NIH Roadmap Epigenomic Project and related international human epigenome projects from 10 countries. Speakers include investigators currently participating in these large-scale projects.
Speaker 1 of 1
* Ting Wang, Washington University, USA

Monday, March 30 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
Room: Longs/Grays Peaks

Speaker 1 of 6
* Barbara J. Meyer, University of California, Berkeley, USA

Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
Room: Longs/Grays Peaks

Speaker 2 of 6
Steven Henikoff, Fred Hutchinson Cancer Research Center, USA
Nucleosome Barriers to Transcription

Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
Room: Longs/Grays Peaks

Speaker 3 of 6
Alicia N. Schep, Stanford University, USA
Short Talk: NucleoATAC: Structured ATAC-seq Signal Around Nucleosomes Enables High-Resolution Nucleosome Positioning

Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
Room: Longs/Grays Peaks

Speaker 4 of 6
B. Franklin Pugh, Pennsylvania State University, USA
Genome-Wide Organization of Chromatin

Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
Room: Longs/Grays Peaks

Speaker 5 of 6
Jeffrey N. McKnight, Fred Hutchinson Cancer Research Center, USA
Short Talk: Global Relocalization of the Rpd3 Histone Deacetylase Drives Quiescence Entry in S. cerevisiae

Monday, March 30 | 5:00PM - 7:15PM
Nucleosome Dynamics
Room: Longs/Grays Peaks

Speaker 6 of 6
Jason D. Lieb, University of Chicago, USA
Evidence for Lamin A Function at Enhancers, with Implications for Hutchinson-Gilford Progeria

Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 6
* Anne C. Ferguson-Smith, University of Cambridge, UK


Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 6
Wolf Reik, Babraham Institute, UK
Epigenetic Reprogramming in Mammalian Development


Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 6
Matthew C. Lorincz, University of British Columbia, Canada
Impact of LTR Retrotransposons on the Transcriptome and Methylome in the Mouse Germline


Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 6
Jonathan I. Gent, University of Georgia, USA
Short Talk: RNA-Directed DNA Methylation in Suppression of Intronic Transposons: Minimizing Collateral Damage on Host Gene Expression


Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
This session is from DNA Methylation
Room: Quandary Peak

Speaker 5 of 6
Marius Walter, Institut Curie, France
Short Talk: Transposon Regulation upon Acute Loss of DNA Methylation


Monday, March 30 | 5:00PM - 7:15PM
DNA Methylation in Early Development
This session is from DNA Methylation
Room: Quandary Peak

Speaker 6 of 6
Vincent Colot, École Normale Supérieure, France
Molecular and Developmental Basis of Progressive DNA Methylation across Generations


Monday, March 30 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, March 30 | 7:30PM - 10:00PM
Poster Session 1
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 1 of 7
* Bas van Steensel, Netherlands Cancer Institute, Netherlands

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 2 of 7
Barbara J. Meyer, University of California, Berkeley, USA
Condensin-Driven Remodeling of X-Chromosome Topology during Dosage Compensation

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 3 of 7
Elphège P. Nora, University of California San Francisco, USA
Short Talk: Life without CTCF (at Least for a Short While)

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 4 of 7
Sarah Elderkin, Babraham Institute, UK
Short Talk: Polycomb Repressive Complex PRC1 Spatially Constrains the Mouse Embryonic Stem Cell Genome to Regulate Pluripotency

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 5 of 7
Iestyn Whitehouse, Memorial Sloan Kettering Cancer Center, USA
Chromatin Assembly: A View from the Lagging Strand

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 6 of 7
Natasha E. Weiser, University of Michigan, USA
Short Talk: MORC-1 Regulates Endogenous Small RNAs, Chromatin Organization and Germline Immortality

Tuesday, March 31 | 8:00AM - 11:00AM
Functional Chromatin Domains
Room: Longs/Grays Peaks

Speaker 7 of 7
Manolis Kellis, Massachusetts Institute of Technology, Broad Institute, USA
Interplay between Chromatin State, Regulator Binding and Regulatory Motifs

Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 8
* Margaret A. Goodell, Baylor College of Medicine, USA


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 8
Timothy H. Bestor, Columbia University College of Physicians and Surgeons, USA
FBXL10 Defends Polycomb-Bound Genes Against Hypermethylation


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 8
Xiaodong Cheng, Emory University, USA
Generation, Recognition and Erasure (GRE) of 5-Methylcytosine and its Oxidative Derivatives


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 8
Sriharsa Pradhan, New England Biolabs, USA
Regulation of DNMT1 Stability and Activity by Reader, Writer, Eraser and MicroRNA


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 5 of 8
Jiahao Huang, Babraham Institute, UK
Short Talk: Histone Modifiers Maintain Fidelity of de novo DNA Methylation in Growing Oocytes


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 6 of 8
Jafar Sharif, RIKEN IMS, Japan
Short Talk: Protracted NP95 Binding to Hemimethylated DNA Disrupts SETDB1-Mediated Proviral Silencing


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 7 of 8
Robert A. Martienssen, Cold Spring Harbor Laboratory, USA
Genome Reprogramming by Histone Variants and Small RNA


Tuesday, March 31 | 8:00AM - 11:45AM
Regulation and Reading of DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 8 of 8
Manu J. Dubin, Gregor Mendel Institute, Austria
Short Talk: DNA Methylation Variation in Arabidopsis Has a Genetic Basis and Shows Evidence of Local Adaptation


Tuesday, March 31 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Tuesday, March 31 | 11:00AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 11:00AM - 2:30PM
On Own for Lunch


Tuesday, March 31 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Tuesday, March 31 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 1 of 7
* Manolis Kellis, Massachusetts Institute of Technology, Broad Institute, USA

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 2 of 7
Joanna Wysocka, Stanford University, USA
Retroelement Reactivation in Human Preimplantation Development

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 3 of 7
Christopher W. Ng, Massachusetts Institute of Technology, USA
Short Talk: Epigenetic Ensembles Presage Transcriptional Changes in Differentiation and Disease

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 4 of 7
Karine G. Le Roch, University of California, Riverside, USA
Short Talk: Association between Chromatin Structure, Gene Regulation and Pathogenicity in the Human Malaria Parasite, Plasmodium falciparum

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 5 of 7
Andrew Dimond, Babraham Institute, UK
Short Talk: Developmental Gene Promoters Establish Poised Enhancer Contacts in Embryonic Stem Cells

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 6 of 7
Jeremie F. Poschmann, Genome Institute of Singapore, Singapore
Short Talk: Large-Scale Mapping of Chromatin-Altering Polymorphisms Reveals Molecular Drivers of Human Disease

Tuesday, March 31 | 5:00PM - 7:15PM
Chromatin Regulation of Development
Room: Longs/Grays Peaks

Speaker 7 of 7
John A. Stamatoyannopoulos, Altius Institute for Biomedical Sciences, USA
Encoding Epigenesis

Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 6
* Matthew C. Lorincz, University of British Columbia, Canada


Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 6
Joseph F. Costello, University of California, San Francisco, USA
The Function of Intermediate DNA Methylation


Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 6
Wenfeng An, South Dakota State University, USA
Short Talk: Retrotransposing Single-Copy Sequences into the Mouse Genome Reveals Sloping Shores: A Graded Influence of Hypomethylated CpG Islands on Flanking CpG Sites


Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 6
Marisa S. Bartolomei, University of Pennsylvania Perelman School of Medicine, USA
Insulators, CTCF and DNA Methylation in Imprinted Gene Clusters


Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 5 of 6
Anne C. Ferguson-Smith, University of Cambridge, UK
Genomic Imprinting and Parental-Origin Effects


Tuesday, March 31 | 5:00PM - 7:15PM
Intermediate and Allele-Specific DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 6 of 6
Claude Becker, Max Planck Institute for Developmental Biology, Germany
Short Talk: Maternal Transmission of Increased Salt Stress Tolerance in Arabidopsis Is Linked to DNA Methylation


Tuesday, March 31 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, March 31 | 7:30PM - 10:00PM
Poster Session 2
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 1 of 7
* Erez Lieberman-Aiden, Baylor College of Medicine, USA

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 2 of 7
Noam Kaplan, University of Massachusetts Medical School, USA
How the 1D Genome Encodes 3D Topologically Associating Domains

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 3 of 7
Edith Heard, European Molecular Biology Laboratory, Germany
The Dynamics of X-Chromosome Structure and Activity during X Inactivation

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 4 of 7
Suhas S.P. Rao, Baylor College of Medicine, USA
Short Talk: Extremely High-Resolution 3D Maps of Human and Mouse Genomes Across Lineages and during Differentiation Reveal Principles of Chromatin Looping

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 5 of 7
Bas van Steensel, Netherlands Cancer Institute, Netherlands
Mapping Genome – Nuclear Lamina Interactions in Single Cells

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 6 of 7
Peter Fraser, Florida State University, USA
Single Molecule Analyses of Chromosome Folding and Genome Organization by Single-Cell Hi-C

Wednesday, April 01 | 8:00AM - 11:15AM
Higher-Order Chromatin Organization
Room: Longs/Grays Peaks

Speaker 7 of 7
Robert A. Beagrie, MRC Clinical Sciences Centre, UK
Short Talk: Novel, Ligation-Free Method for Identifying Chromatin Interactions Genome-Wide

Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 7
Margaret A. Goodell, Baylor College of Medicine, USA
DNMT3A in Normal and Malignant Hematopoiesis


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 7
Peter A. Jones, Van Andel Research Institute, USA
Cancer Therapy


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 7
Benjamin Leadem, NIDDK, National Institutes of Health, USA
Short Talk: Novel Inhibitors of KDM5 Family Proteins Synergize with DNMT Inhibitors to Regulate Gene Expression and Inhibit Proliferation of Breast Cancer Cells


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 7
Jeanne F. Loring, The Scripps Research Institute, USA
Dynamics of DNA Methylation in Human Pluripotent Stem Cell Differentiation


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 5 of 7
Ralf Gilsbach, University of Freiburg, Germany
Short Talk: Stage-Specific Gene Expression Programs in Cardiomyocytes Rely on Dynamic CpG-Methylation or Polycomb Repressive Marks


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 6 of 7
Amos Tanay, Weizmann Institute, Israel
Single-Cell Transcriptional and Epigenomic Approaches to Complex Cell Populations


Wednesday, April 01 | 8:00AM - 11:45AM
Perturbations of DNA Methylation in Disease
This session is from DNA Methylation
Room: Quandary Peak

Speaker 7 of 7
Yvette A. Luyten, New England Biolabs, USA
Short Talk: Bacterial DNA Methyltransferases: A New “Class” of Type I Restriction Modification Enzymes Utilizing Two Distinct DNA Methyltransferase Genes


Wednesday, April 01 | 9:20AM - 9:40AM
Coffee Break
Room: Longs Peak Foyer


Wednesday, April 01 | 11:15AM - 1:00PM
Poster Setup
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, April 01 | 1:00PM - 10:00PM
Poster Viewing
Room: Colorado Rockies Ballroom


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 7
* Amos Tanay, Weizmann Institute, Israel


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 7
* Remo Rohs, University of Southern California, USA
Modeling of the Effect of DNA Methylation on DNA Shape and Protein-DNA Binding


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 7
Michael M. Hoffman, University of Toronto, Canada
Transcription Factor Binding in an Expanded Epigenetic Alphabet


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 7
Önder Kartal, University of Zürich, Switzerland
An Information-Theoretic Approach to Discover Differential DNA Methylation in Plants Suggests that Diversity Is Highest in the CG Context


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 5 of 7
Fabian Müller, Stanford University, USA
Computational Methods for the DEEP Characterization of DNA Methylation BLUEPRINTs


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 6 of 7
Yaping Liu, Cincinnati Children's Hospital Medical Center, USA
meQTLFinder: A Bayesian Model to Detect meQTL by Using Chromatin States and Chromatin Interaction Prior Information


Wednesday, April 01 | 2:30PM - 4:30PM
Workshop: Modeling DNA Methylation
This session is from DNA Methylation
Room: Quandary Peak

Speaker 7 of 7
David Gokhman, Hebrew University of Jerusalem, Israel
Paleo-Epigenetics: Reconstructing the DNA Methylation Maps of Archaic Hominins


Wednesday, April 01 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
Room: Longs/Grays Peaks

Speaker 1 of 6
* John L. Rinn, University of Colorado Boulder, USA

Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
Room: Longs/Grays Peaks

Speaker 2 of 6
Amy E. Pasquinelli, University of California, San Diego, USA
The Primary Target of let-7 MicroRNA

Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
Room: Longs/Grays Peaks

Speaker 3 of 6
Haifan Lin, Yale University, USA
Multifaceted Roles of the Piwi-piRNA Pathway in Gene Regulation

Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
Room: Longs/Grays Peaks

Speaker 4 of 6
Alla Grishok, Columbia University Medical Center, USA
Short Talk: Connecting Euchromatin and Endogenous RNAi in C. elegans

Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
Room: Longs/Grays Peaks

Speaker 5 of 6
Sam (Guoping) Gu, Rutgers University, USA
Short Talk: siRNA-Mediated Chromatin Regulation and Multigenerational Homeostasis of Germline Gene Expression in C. elegans

Wednesday, April 01 | 5:00PM - 7:15PM
Small RNA
Room: Longs/Grays Peaks

Speaker 6 of 6
Craig S. Pikaard, HHMI/Indiana University, USA
RNA Silencing and Epigenetic Inheritance

Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 6
* Peter A. Jones, Van Andel Research Institute, USA


Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 6
Stephan Beck, University College London, UK
Insights from Methylome Analysis


Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 6
Peter W. Laird, Van Andel Research Institute, USA
Cancer Methylomes


Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 6
Michiel Vermeulen, Radboud University, Netherlands
Quantitative Interaction Proteomics for Epigenetics


Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
This session is from DNA Methylation
Room: Quandary Peak

Speaker 5 of 6
Xueguang Sun, Zymo Research Corp, USA
Short Talk: Mirror Bisulfite Sequencing (Mirror-Seq): A Novel Sequencing Method for Genome-Wide Profiling of 5-Hydroxymethylcytosine with Single-Base Resolution


Wednesday, April 01 | 5:00PM - 7:15PM
DNA Methylation as a Biomarker
This session is from DNA Methylation
Room: Quandary Peak

Speaker 6 of 6
Shinji Maegawa, Temple University, USA
Short Talk: DNA Methylation Drift as a Marker of Lifespan in Mammals


Wednesday, April 01 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, April 01 | 7:30PM - 10:00PM
Poster Session 3
Room: Colorado Rockies Ballroom


Thursday, April 02 | 7:00AM - 8:00AM
Breakfast
Room: Colorado Rockies Ballroom


Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 1 of 7
* Alexander Meissner, Max Planck Institute for Molecular Genetics, Germany

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 2 of 7
Joseph R. Ecker, The Salk Institute for Biological Studies, USA
Human Body Epigenome Maps Reveal Noncanonical DNA Methylation Variation

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 3 of 7
Bing Ren, Ludwig Institute for Cancer Research, USA
Integrative Analysis of Haplotype-Resolved Epigenomes across Human Tissues

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 4 of 7
Daniel Zilberman, University of California, Berkeley, USA
Molecular Co-Evolution of Genomes and Chromatin

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 5 of 7
Andrew G. Clark, Cornell University, USA
Short Talk: Analysis of Novel Marsupial-Specific Imprinted Genes and their DMRs in the Opossum, Monodelphis domestica

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 6 of 7
Camila O. dos Santos, Cold Spring Harbor Laboratory, USA
Short Talk: An Epigenetic Memory of Pregnancy in the Mouse Mammary Gland

Thursday, April 02 | 8:00AM - 11:15AM
Genome-Wide DNA Methylation II (Joint)
Room: Longs/Grays Peaks

Speaker 7 of 7
Dirk Schübeler, Friedrich Miescher Institute for Biomedical Research, Switzerland
Sequence and Chromatin Determinants of DNA Methylation

Thursday, April 02 | 9:40AM - 10:00AM
Coffee Break
Room: Longs Peak Foyer


Thursday, April 02 | 11:15AM - 2:30PM
On Own for Lunch


Thursday, April 02 | 2:30PM - 4:30PM
Workshop 2: ENCODE Datasets Tutorial
Room: Longs/Grays Peaks

Speaker 1 of 1
* Feng Yue, Pennsylvania State University, USA

Thursday, April 02 | 4:30PM - 5:00PM
Coffee Available
Room: Longs Peak Foyer


Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
Room: Longs/Grays Peaks

Speaker 1 of 6
* Amy E. Pasquinelli, University of California, San Diego, USA

Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
Room: Longs/Grays Peaks

Speaker 2 of 6
John L. Rinn, University of Colorado Boulder, USA
RNA-Binding Proteins Interact Specifically with Transposable Element Sequence in Human Genes

Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
Room: Longs/Grays Peaks

Speaker 3 of 6
Jindan Yu, Northwestern University Feinberg School of Medicine, USA
Short Talk: LncRNA HOTAIR Enhances the Androgen Receptor-Mediated Transcriptional Program and Drives Castration-Resistant Prostate Cancer

Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
Room: Longs/Grays Peaks

Speaker 4 of 6
L. Stirling Churchman, Harvard Medical School, USA
Short Talk: High-Resolution Architecture of Human Transcriptional Activity Revealed by Native Elongating Transcript Sequencing

Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
Room: Longs/Grays Peaks

Speaker 5 of 6
Gilad Fuchs, Weizmann Institute of Science, Israel
Short Talk: Cotranscriptional Histone H2B Monoubiquitylation Is Tightly Coupled with RNA Polymerase II Elongation Rate

Thursday, April 02 | 5:00PM - 7:00PM
Long Noncoding RNA
Room: Longs/Grays Peaks

Speaker 6 of 6
Mitchell Guttman, California Institute of Technology, USA
lncRNAs: Function and Mechanism in Controlling Cellular Identity

Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
This session is from DNA Methylation
Room: Quandary Peak

Speaker 1 of 4
* Xiaodong Cheng, Emory University, USA


Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
This session is from DNA Methylation
Room: Quandary Peak

Speaker 2 of 4
Frédéric L. Chedin, University of California, Davis, USA
Epigenomics Signatures of R-Loop Forming Regions


Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
This session is from DNA Methylation
Room: Quandary Peak

Speaker 3 of 4
Chuan He, University of Chicago, USA
Genome-Wide Sequencing of 5hmC and 5fC


Thursday, April 02 | 5:00PM - 7:00PM
DNA Methylation Turnover
This session is from DNA Methylation
Room: Quandary Peak

Speaker 4 of 4
Salvatore Oliviero, Human Genetics Foundation, HuGeF, Italy
Short Talk: Single-Base Resolution Analysis of 5-Formyl and 5-Carboxyl Cytosine Reveals DNA Methylation/Demethylation Dynamics in the Mammalian Genome


Thursday, April 02 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Longs/Grays Peak


Thursday, April 02 | 7:00PM - 7:15PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
This session is from DNA Methylation
Room: Quandary Peak


Thursday, April 02 | 7:15PM - 8:15PM
Social Hour with Lite Bites
Room: Colorado Rockies Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, April 02 | 8:00PM - 11:00PM
Entertainment
Room: Colorado Rockies Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, April 02 | 8:00PM - 11:00PM
Cash Bar
Room: Colorado Rockies Ballroom


Friday, April 03 | 10:25AM - 10:25AM
Departure


*Session Chair.