Past Meeting | Keystone Symposia

This meeting took place in the past. Here is a list of meetings that are related:
	Innate Immune Receptors: Roles in Immunology and Beyond (2019M1)
Innate and Non-Classical Immune Cells in Cancer Immunotherapy (2019C5)
Regulation and Dysregulation of Innate Immunity in Disease (2018B9)
Type I Interferon: Friend and Foe Alike (2017X6)
Pattern Recognition Signaling: From Innate Immunity to Inflammatory Disease (2017X5)
Nucleic Acid Sensing Pathways: Innate Immunity, Immunobiology and Therapeutics (2016E2)

Web Desc
Innate Immunity and Determinants of Microbial Pathogenesis joint with Mechanisms of Pro-Inflammatory Diseases Organizer(s): Robert L. Modlin, Jenny P.Y. Ting and Foo Y. Liew Date: April 19 - 24, 2015 Location: Resort at Squaw Creek, Olympic Valley, CA, USA Sponsored by BioLegend, Inc. Summary of Meeting: With the emergence of drug-resistant organisms, advances in immunology, insights gained from understanding the normal and disease microbiome, and rapid technological advances including high-throughput sequencing and robotics, the time is ripe to hold a second Keystone Symposia meeting on this topic like the one held in 2000. This meeting focuses on innate and adaptive immunity to microbial infections. Microbial infections pose major health problems worldwide, but also represent extraordinary models to study immune regulation. Important advances in immunology have been made in recent years and have led to a new understanding of host-pathogen interactions. This conference explores the interaction of the innate and adaptive immune response in host defense against microbial infection. This meeting aims to bring together immunologists who study basic mechanisms and those who study infectious agents to formulate new strategies to control some of the world’s most deadly diseases. Scholarship Deadline: December 18 2014 Discounted Abstract Deadline: December 18 2014 Abstract Deadline: January 21 2015 Discounted Registration Deadline: February 19 2015 Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting: We gratefully acknowledge additional support for this conference from: We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements: Dynavax Technologies Corporation Genentech, Inc. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: We gratefully acknowledge the generous grant for this conference provided by: National Institute of Allergy and Infectious Diseases (NIAID) Grant No. 1R13AI116010-01 Funding for this conference was made possible (in part) by 1 R13 AI 116010 - 01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising: Click here to view more of these organizations Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds: Click here to view more of these organizations

Web Desc

Innate Immunity and Determinants of Microbial Pathogenesis

joint with Mechanisms of Pro-Inflammatory Diseases

Organizer(s): Robert L. Modlin, Jenny P.Y. Ting and Foo Y. Liew

Date: April 19 - 24, 2015
Location: Resort at Squaw Creek, Olympic Valley, CA, USA

Program


Sunday, April 19 \| 4:00PM - 8:00PM Arrival and Registration Room: Lobby Alcove
Sunday, April 19 \| 6:00PM - 8:00PM Welcome Mixer Room: Lobby Alcove No registration fees are used to fund alcohol served at this function.
Monday, April 20 \| 7:00AM - 8:00AM Breakfast Room: Alpine Ballroom
Monday, April 20 \| 8:00AM - 9:30AM Keynote Session (Joint) Room: Grand Sierra A-D Speaker 1 of 3 * Robert L. Modlin, University of California, Los Angeles, USA Introduction
Monday, April 20 \| 8:00AM - 9:30AM Keynote Session (Joint) Room: Grand Sierra A-D Speaker 2 of 3 Richard A. Flavell, HHMI/Yale University School of Medicine, USA Inflammasomes in Health, Dysbiosis and Disease
Monday, April 20 \| 8:00AM - 9:30AM Keynote Session (Joint) Room: Grand Sierra A-D Speaker 3 of 3 Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA Innate Immune Sensing of Cytosolic Nucleic Acids
Monday, April 20 \| 9:40AM - 10:00AM Coffee Break Room: Sierra Prefunction
Monday, April 20 \| 9:50AM - 12:00PM Innate Immunity (Joint) Room: Grand Sierra A-D Speaker 1 of 6 * Virginia Pascual, Cornell University, USA
Monday, April 20 \| 9:50AM - 12:00PM Innate Immunity (Joint) Room: Grand Sierra A-D Speaker 2 of 6 Vishva M. Dixit, Genentech, Inc., USA New Pathways of Inflammasome Activation
Monday, April 20 \| 9:50AM - 12:00PM Innate Immunity (Joint) Room: Grand Sierra A-D Speaker 3 of 6 Yong-Jun Liu, Sanofi, USA Sensing of DNA and RNA
Monday, April 20 \| 9:50AM - 12:00PM Innate Immunity (Joint) Room: Grand Sierra A-D Speaker 4 of 6 Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA NLRs in Inflammasome and Non-Inflammasome Functions
Monday, April 20 \| 9:50AM - 12:00PM Innate Immunity (Joint) Room: Grand Sierra A-D Speaker 5 of 6 Pedro Moura-Alves, Max Planck Institute for Infection Biology, Germany Short Talk: PAMPing AhR
Monday, April 20 \| 9:50AM - 12:00PM Innate Immunity (Joint) Room: Grand Sierra A-D Speaker 6 of 6 Scott W. Canna, Children's Hospital of Pittsburgh, University of Pittsburgh, USA Short Talk: Activating Mutations in NLRC4 Cause Recurrent Macrophage Activation Syndrome: Blame it on IL-18?
Monday, April 20 \| 12:00PM - 1:00PM Poster Setup Room: Alpine Ballroom
Monday, April 20 \| 12:00PM - 5:00PM On Own for Lunch
Monday, April 20 \| 1:00PM - 10:00PM Poster Viewing Room: Alpine Ballroom
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 1 of 9 * Jae U. Jung, Keck School of Medicine of University of Southern California, USA
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 2 of 9 Emily M. Eshleman, University of Colorado School of Medicine, USA Myeloid Cell IFNGR1 Down Regulation Exacerbates Bacterial Infections
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 3 of 9 Matteo Gentili, Institut Curie, France Intercellular Transmission of Innate Immune Signaling by Packaging of the Second Messenger cGAMP in Viral Particles
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 4 of 9 Jarrod S. Johnson, Seattle Biomedical Research Institute, USA HIV-1 Alters the Threshold for Type I Interferon Signaling in Dendritic Cells
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 5 of 9 Ken Chung-Ren Pang, Walter and Eliza Hall Institute of Medical Research, Australia Sidt2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 6 of 9 Jan Rehwinkel, Weatherall Institute of Molecular Medicine, University of Oxford, UK Lentiviruses Transfer the Antiviral Second Messenger cGAMP between Cells
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 7 of 9 Beiyun Caitlin Liu, Tufts University, USA Type-I IFN-Independent Induction and Activation of Caspase-11 toward L. pneumophila
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 8 of 9 Clinton J. Bradfield, NIH, USA Human GBPs Recognize a New Class of DAMPs to Mobilize Cell-Autonomous Immunity to Bacterial Pathogens
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: IFN Room: Grand Sierra AB Speaker 9 of 9 Jessica F. Almine, University of Dundee, UK IFI16 and cGAS Co-Operate in DNA Sensing in Human Keratinocytes
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 7 * Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 7 Irving C. Allen, Virginia Tech, USA NLRX1 Attenuates Inflammation and Tumorigenesis through the Negative Regulation of AKT and NF-kappaB Signaling
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 7 Po-Lin Huang, Academia Sinica, Taiwan Skeletal Muscle IL-15/IL-15Ralpha Promotes CD8+ T-Cell Function and Autoimmune Myositis
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 7 Sebastian Günther, University of Maryland School of Medicine, USA Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 7 Teja Celhar, Singapore Immunology Network, Singapore Elimination of the NLRP3 Inflammasome Prevents the Development of Lupus-Associated Traits in a Mouse Model of Autoimmunity
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 6 of 7 Rachel A. Gottschalk, NIAID, National Institutes of Health, USA Distinct Sensitivities of NFkappaB and MAPK to TLR Ligation Support Robust Low-Noise Inflammatory Responses
Monday, April 20 \| 2:30PM - 4:30PM Workshop 1: Innate Immunity and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 7 of 7 Sebastien Tauzin, University of Wisconsin-Madison, USA Redox and Src Family Kinase Signaling Control Macrophage-Mediated Resolution of Inflammation
Monday, April 20 \| 4:30PM - 5:00PM Coffee Available Room: Sierra Prefunction
Monday, April 20 \| 5:00PM - 7:00PM Innate Immune Sensing and Consequences in Microbial Infectio n Room: Grand Sierra AB Speaker 1 of 5 * Alan Sher, NIAID, National Institutes of Health, USA
Monday, April 20 \| 5:00PM - 7:00PM Innate Immune Sensing and Consequences in Microbial Infectio n Room: Grand Sierra AB Speaker 2 of 5 Jae U. Jung, Keck School of Medicine of University of Southern California, USA Roles of Pattern Recognizing Receptors and Autophagy in Antiviral Immune Response
Monday, April 20 \| 5:00PM - 7:00PM Innate Immune Sensing and Consequences in Microbial Infectio n Room: Grand Sierra AB Speaker 3 of 5 Stanley M. Lemon, University of North Carolina at Chapel Hill, USA Type 1 Interferon Responses Determine Permissiveness and Host Species Range of Human Hepatitis A Virus
Monday, April 20 \| 5:00PM - 7:00PM Innate Immune Sensing and Consequences in Microbial Infectio n Room: Grand Sierra AB Speaker 4 of 5 Genhong Cheng, University of California, Los Angeles, USA Balancing Inflammatory Responses during Acute and Chronic Infections
Monday, April 20 \| 5:00PM - 7:00PM Innate Immune Sensing and Consequences in Microbial Infectio n Room: Grand Sierra AB Speaker 5 of 5 Arun K. Mankan, University of Bonn, Institute of Molecular Medicine, Germany Short Talk: Cytosolic RNA:DNA Hybrids Activate the cGAS-STING Axis
Monday, April 20 \| 5:00PM - 7:00PM Innate Triggers of Adaptive Immunity This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 5 * John J. O'Shea, NIAMS, National Institutes of Health, USA
Monday, April 20 \| 5:00PM - 7:00PM Innate Triggers of Adaptive Immunity This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 5 Mark S. Anderson, University of California, San Francisco, USA Control of Immune Tolerance by Aire-Expressing Cells
Monday, April 20 \| 5:00PM - 7:00PM Innate Triggers of Adaptive Immunity This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 5 Hideki Ueno, Icahn School of Medicine at Mount Sinai, USA T Follicular Helper Cells in Autoimmunity in Humans
Monday, April 20 \| 5:00PM - 7:00PM Innate Triggers of Adaptive Immunity This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 5 Averil I. Ma, University of California, San Francisco, USA Short Talk: A20 Restricts IL1b Ubiquitination and NLRP3 Inflammasome Activity
Monday, April 20 \| 5:00PM - 7:00PM Innate Triggers of Adaptive Immunity This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 5 Simone Caielli, Baylor Institute for Immunology Research, USA Short Talk: Oxidized Mitochondrial DNA Is a Powerful Activator of Human pDCs and Induces a Lupus-Specific CD4 T Cell Phenotype
Monday, April 20 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Alpine Ballroom No registration fees are used to fund alcohol served at this function.
Monday, April 20 \| 7:30PM - 10:00PM Poster Session 1 Room: Alpine Ballroom
Tuesday, April 21 \| 7:00AM - 8:00AM Breakfast Room: Alpine Ballroom
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 1 of 7 * Foo Y. Liew, University of Glasgow, UK
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 2 of 7 Akira Shizuo, Osaka University, Japan Control of the Inflammatory and Immune Responses by the Ribonuclease, Regnase-1
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 3 of 7 Daniel Kastner, National Institutes of Health, USA Dissecting New Inflammatory Pathways through Genetics
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 4 of 7 Virginia Pascual, Cornell University, USA Novel Insights into Human SLE Pathogenesis
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 5 of 7 Robert L. Modlin, University of California, Los Angeles, USA Innate Immunity in TB
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 6 of 7 Hubertus Hochrein, Bavarian Nordic, Germany Short Talk: IFN-lambda Production of CD8 cDCs in Response to DNA-Viruses, Transfected dsDNA or Cyclic-di-Nucleotides Depends on STING
Tuesday, April 21 \| 8:00AM - 11:15AM Innate Immunity in Inflammation and Disease (Joint) Room: Grand Sierra A-D Speaker 7 of 7 Seth L. Masters, Walter and Eliza Hall Institute, Australia Short Talk: Aberrant Actin Depolymerization Triggers the Pyrin Inflammasome and Autoinflammatory Disease that Is Dependent on IL-18, not IL-1beta
Tuesday, April 21 \| 9:20AM - 9:40AM Coffee Break Room: Sierra Prefunction
Tuesday, April 21 \| 11:15AM - 1:00PM Poster Setup Room: Alpine Ballroom
Tuesday, April 21 \| 11:15AM - 12:15PM On Own for Lunch
Tuesday, April 21 \| 1:00PM - 10:00PM Poster Viewing Room: Alpine Ballroom
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 1 of 9 * John D. MacMicking, Yale University, USA
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 2 of 9 André Alves Dias, Oswaldo Cruz Foundation, Brazil The Role of TLR9 Activation in the Host Immune Response during Type II Reaction in Leprosy
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 3 of 9 Robert O. Watson, Texas A&M Health Science Center, USA cGAS Detects Mycobacterium tuberculosis DNA to Activate both Type I Interferon and Autophagy
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 4 of 9 Trude Helen Flo, Norwegian University of Science, Norway Keap1 Regulates Inflammatory Signaling in M. avium-Infected Human Macrophages
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 5 of 9 Jennifer R. Honda, National Jewish Health, USA Polar Lipids of Nontuberculous Mycobacteria Likely Contribute to Neutralization of Cathelicidin
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 6 of 9 Susan Realegeno, University of California, Los Angeles, USA Identifying TLR and IFN-g Inducible Antimicrobial Responses Against Mycobacteria in Human Macrophages
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 7 of 9 Leonardo Ribeiro Batista Silva, Fundação Oswaldo Cruz, Brazil Insulin-Like Growth Factor-I (IGF-I) Signaling Pathway Inhibits the STAT1 Activation via SOCS3 in Mycobacterium leprae-Stimulated Macrophases
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 8 of 9 Kirsten E. Wiens, New York University School of Medicine, USA Differential Type I Interferon Induction by Distinct Mycobacterium tuberculosis Strains Despite Similar Access to the Host Cytosol
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Mycobacteria Room: Grand Sierra AB Speaker 9 of 9 Chien-Hsiung Yu, University of Queensland Diamantina Institute, Australia RP105 Dependent Activation of PI3Kdelta Promotes Cytokine Trafficking in Mycobacteria-Infected Macrophages
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 9 * Raphaela Theresia Goldbach-Mansky, NIAID, National Institutes of Health, USA
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 9 Nagaraj Kerur, University of Kentucky, USA Innate Immune Mechanisms of Alu RNA-Induced Age-Related Macular Degeneration
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 9 Siobhán A-L Smith, Royal College of Surgeons in Ireland, Ireland Altered miRNA Expression in Monocytes Contributes to Dysregulated IL-16 Levels in SLE
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 9 Marcel F. Nold, Monash University, Australia Serum Interleukin 38 Is Associated with Disease Severity and Organ Involvement in Systemic Lupus Erythematosus
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 9 Romain F. Banchereau, Baylor Institute for Immunology Research, USA Longitudinal Immunoprofiling of SLE Patients Identifies Transcriptional Biomarkers of Disease Activity and Response to Treatment
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 6 of 9 Nelson Gekara, Umeå University, Sweden DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 7 of 9 Nadia Jeremiah, Institute Imagine, France An IntereSTING Germline Mutation Underlying a Familial Inflammatory Syndrome with Lupus-Like Manifestations
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 8 of 9 Dong-Ming Su, University of North Texas Health Science Center, USA Thymic Involution Perturbs Negative Selection Leading to Increased Release of Self-Reactive T Cells that Induce Chronic Inflammation in the Elderly
Tuesday, April 21 \| 2:30PM - 4:30PM Workshop 2: Biomarkers and Mechanisms of Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 9 of 9 Hye-Lin Ha, NIAID, National Institutes of Health, USA IL-17 Drives Psoriatic Inflammation via Distinct, Target Cell-Specific Mechanisms
Tuesday, April 21 \| 4:30PM - 5:00PM Coffee Available Room: Sierra Prefunction
Tuesday, April 21 \| 5:00PM - 7:00PM Innate Regulation of Adaptive Immunity Room: Grand Sierra AB Speaker 1 of 6 * Cathryn R. Nagler, University of Chicago, USA
Tuesday, April 21 \| 5:00PM - 7:00PM Innate Regulation of Adaptive Immunity Room: Grand Sierra AB Speaker 2 of 6 Foo Y. Liew, University of Glasgow, UK The Role of Cytokines in Infection and Inflammation
Tuesday, April 21 \| 5:00PM - 7:00PM Innate Regulation of Adaptive Immunity Room: Grand Sierra AB Speaker 3 of 6 Alan Sher, NIAID, National Institutes of Health, USA Cytokine and Lipid Mediator Cross-Talk in the Innate Immune Response to Mycobacterium tuberculosis
Tuesday, April 21 \| 5:00PM - 7:00PM Innate Regulation of Adaptive Immunity Room: Grand Sierra AB Speaker 4 of 6 Marco Colonna, Washington University School of Medicine, USA Innate Lymphoid Cells in Immunity
Tuesday, April 21 \| 5:00PM - 7:00PM Innate Regulation of Adaptive Immunity Room: Grand Sierra AB Speaker 5 of 6 Jesse C. Nussbaum, University of California, San Francisco, USA Short Talk: Group 2 Innate Lymphocytes Are Early Effectors that Cooperate with Adaptive Immunity after Helminth Infection
Tuesday, April 21 \| 5:00PM - 7:00PM Innate Regulation of Adaptive Immunity Room: Grand Sierra AB Speaker 6 of 6 Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne, Switzerland Short Talk:
Tuesday, April 21 \| 5:00PM - 7:15PM Sterile Nucleic Acid Sensing and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 5 * Mark S. Anderson, University of California, San Francisco, USA
Tuesday, April 21 \| 5:00PM - 7:15PM Sterile Nucleic Acid Sensing and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 5 Yanick Crow, University of Edinburgh, UK Human Type I Interferonopathies
Tuesday, April 21 \| 5:00PM - 7:15PM Sterile Nucleic Acid Sensing and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 5 Gregory M. Barton, University of California, Berkeley, USA Regulation of Toll-Like Receptors
Tuesday, April 21 \| 5:00PM - 7:15PM Sterile Nucleic Acid Sensing and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 5 Glen N. Barber, University of Miami, USA STING and Sterile Inflammation
Tuesday, April 21 \| 5:00PM - 7:15PM Sterile Nucleic Acid Sensing and Disease This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 5 Matthew G. Blango, University of Utah, USA Short Talk: Identification of Hyper-Edited, Immune-Relevant RNA in Activated Macrophages
Tuesday, April 21 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Alpine Ballroom No registration fees are used to fund alcohol served at this function.
Tuesday, April 21 \| 7:30PM - 10:00PM Poster Session 2 Room: Alpine Ballroom
Wednesday, April 22 \| 7:00AM - 8:00AM Breakfast Room: Alpine Ballroom
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 1 of 7 * Yasmine Belkaid, NIAID, National Institutes of Health, USA
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 2 of 7 Alan Aderem, Center for Infectious Disease Research, USA A Systems Approach to Dissecting Immunity
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 3 of 7 Ronald N. Germain, NIAID, National Institutes of Health, USA Single Cell and Systems Level Analysis and Modeling of Innate Immunity
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 4 of 7 Iain D.C. Fraser, NIAID, National Institutes of Health, USA Interrogating Immune Signaling Systems with High-Throughput, High-Content Screening
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 5 of 7 Tsan Sam Xiao, Case Western Reserve University, USA Short Talk: Structure and Regulation of IFI16
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 6 of 7 Roi Avraham, Broad Institute, USA Short Talk: Single Cell Expression Analysis Reveals Co-Variation of Bacterial and Host Factors that Control Infection Outcome
Wednesday, April 22 \| 8:00AM - 11:00AM Systems Biology/Immunomics of Innate Immunity Room: Grand Sierra AB Speaker 7 of 7 Johan Van Weyenbergh, KU Leuven, Belgium Short Talk: Systemic and in situ Transcriptomics Reveal an Innate/Type I IFN Link between Oxidative Burst, Cell Death and Inflammation in Human Cutaneous Leishmaniasis
Wednesday, April 22 \| 8:00AM - 11:00AM Novel Players in the Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 5 * Daniel Kastner, National Institutes of Health, USA
Wednesday, April 22 \| 8:00AM - 11:00AM Novel Players in the Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 5 Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland Metabolic Control of Inflammtion
Wednesday, April 22 \| 8:00AM - 11:00AM Novel Players in the Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 5 Michael L. Stitzel, The Jackson Laboratory for Genomic Medicine, USA Enhancers and Type II Diabetes
Wednesday, April 22 \| 8:00AM - 11:00AM Novel Players in the Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 5 Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA Regulators of Inflammatory Responses
Wednesday, April 22 \| 8:00AM - 11:00AM Novel Players in the Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 5 Benjamin Fowler, University of Kentucky, USA Short Talk: Nucleoside Reverse Transcriptase Inhibitors Possess Intrinsic Anti-Inflammatory Activity
Wednesday, April 22 \| 9:20AM - 9:40AM Coffee Break Room: Sierra Prefunction
Wednesday, April 22 \| 11:00AM - 1:00PM Poster Setup Room: Alpine Ballroom
Wednesday, April 22 \| 11:00AM - 5:00PM On Own for Lunch
Wednesday, April 22 \| 1:00PM - 10:00PM Poster Viewing Room: Alpine Ballroom
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 1 of 9 * Laurel L. Lenz, University of Colorado, USA
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 2 of 9 Jon A. Hagar, University of North Carolina at Chapel Hill, USA Endotoxin Signaling Potentiates Insulin-Induced Acute Hypoglycemia
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 3 of 9 Damien Arnoult, Hopital Paul Brousse, France Endomembranes Act as Platforms for Ubiquitylated Components of NF-kappaB and IRF3 Signaling
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 4 of 9 Marina Zaitseva, Center for Biologics Evaluation and Research, USA Critical Role of GPR14 Receptor in Prostaglandin Production by Human Monocytes in Response to MDP
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 5 of 9 Sarah E. Clark, University of Colorado, USA Regulation of Natural Killer Cell IL-10 Production during Listeria Infection
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 6 of 9 Mathias S. Dick, University of Basel, Switzerland Oligomerization of ASC Serves as Signal Amplification Mechanism for Inflammasomes
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 7 of 9 Naohiro Inohara, University of Michigan Medical School, USA Interleukin-22 Bridges Local Inflammation to Systemic Protection Against Pathobionts after Pathogen-Induced Intestinal Damage
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 8 of 9 Marijke Keestra-Gounder, University of Colorado Denver, USA The ER Stress-Induced Pro-Inflammatory Response Is Mediated by the NOD1/NOD2 Signaling Pathway
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3: Effector Function Room: Grand Sierra AB Speaker 9 of 9 Shie-Liang Hsieh, Academia Sinica, Taiwan Modulation of Influenza Virus-Induced Macrophage Activation by Decoy Receptor 3 (DcR3)
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 9 * Yanick Crow, University of Edinburgh, UK
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 9 Sarah L. Doyle, Trinity College Dublin, Ireland IL-18 Immunotherapy for Neovascular AMD; Tolerability and Efficacy in Non-Human Primates
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 9 Kate Schroder, University of Queensland, Australia Neutrophil Inflammasomes Selectively Drive IL-1beta Maturation but not Cell Death
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 9 Eric P. Hanson, National Institutes of Health, USA Recruitment of A20 by the C-Terminal Ubiquitin-Binding Domain of NEMO Prevents Severe Inflammatory Disease in Humans
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 9 Peter R. Bunyard, Redx Pharma, UK Genetic Deletion of GPR18 Enhances Immune Responses to Pathogenic and Antigenic Challenge
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 6 of 9 Todd Douglas, McGill University, Canada Inflammatory Caspases in the Pathogenesis of Chronic Proliferative Dermatitis in Mice
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 7 of 9 Kiyoshi Hirahara, Graduate School of Medicine, Chiba University, Japan Asymmetry of STAT Action in Driving IL-27 and IL-6 Transcriptional Outputs and Cytokine Specificity
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 8 of 9 Alma-Martina Cepika, Stanford School of Medicine, USA A Blood Stimulation Assay Identifies Monocyte Hyperresponsiveness to Pro-Inflammatory Stimuli in Systemic-Onset Juvenile Idiopathic Arthritis
Wednesday, April 22 \| 2:30PM - 4:30PM Workshop 3 This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 9 of 9 Irina Alexandra Leaf, Biogen, USA Pericyte MyD88 Controls Inflammatory and Fibrotic Responses to Tissue Injury
Wednesday, April 22 \| 4:30PM - 5:00PM Coffee Available Room: Sierra Prefunction
Wednesday, April 22 \| 5:00PM - 7:00PM Microbiome and Innate Immunity Room: Grand Sierra AB Speaker 1 of 5 * Alan Aderem, Center for Infectious Disease Research, USA
Wednesday, April 22 \| 5:00PM - 7:00PM Microbiome and Innate Immunity Room: Grand Sierra AB Speaker 2 of 5 Cathryn R. Nagler, University of Chicago, USA Innate Immune Regulation of Sensitization to Dietary Antigens by Commensal Bacteria
Wednesday, April 22 \| 5:00PM - 7:00PM Microbiome and Innate Immunity Room: Grand Sierra AB Speaker 3 of 5 Yasmine Belkaid, NIAID, National Institutes of Health, USA T Cell Commensals
Wednesday, April 22 \| 5:00PM - 7:00PM Microbiome and Innate Immunity Room: Grand Sierra AB Speaker 4 of 5 Sarkis K. Mazmanian, California Institute of Technology, USA The Gut Microbiome Signals through Genetic Pathways Linked to IBD
Wednesday, April 22 \| 5:00PM - 7:00PM Microbiome and Innate Immunity Room: Grand Sierra AB Speaker 5 of 5 Richard I. Tapping, University of Illinois, USA Short Talk: Toll-Like Receptor 10 Is a B-Cell Intrinsic Suppressor of Adaptive Humoral Immune Responses
Wednesday, April 22 \| 5:00PM - 7:00PM Epigenetic Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 4 Howard Y. Chang, Stanford University, USA LncRNAs and Inflammation
Wednesday, April 22 \| 5:00PM - 7:00PM Epigenetic Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 4 Alexander Tarakhovsky, Rockefeller University, USA Epigenetic Control of Inflammatory Cascades
Wednesday, April 22 \| 5:00PM - 7:00PM Epigenetic Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 4 John J. O'Shea, NIAMS, National Institutes of Health, USA Epigenetic Control of T Cell Fate
Wednesday, April 22 \| 5:00PM - 7:00PM Epigenetic Control of Inflammation This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 4 Chrysothemis Brown, Sloan Kettering Institute, USA Short Talk: Epigenetic Regulation of Th1 Plasticity by Retinoic Acid: A New Paradigm for the Ontogeny of Pathogenic Th17 Cells
Wednesday, April 22 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Alpine Ballroom No registration fees are used to fund alcohol served at this function.
Wednesday, April 22 \| 7:30PM - 10:00PM Poster Session 3 Room: Alpine Ballroom
Thursday, April 23 \| 7:00AM - 8:00AM Breakfast Room: Alpine Ballroom
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 1 of 7 * Akiko Iwasaki, HHMI/Yale University School of Medicine, USA
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 2 of 7 Hana Golding, US Food and Drug Administration, USA Impact of Adjuvants on Antibody Repertoires and Affinity Maturation Against Pandemic Influenza Vaccines
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 3 of 7 Eva Harris, Division of Infectious Diseases and Vaccinology, School of Public Health, USA Antibodies to Dengue Virus Non-Structural Protein 1 Protect Against Endothelial Permeability and Lethal Vascular Leak
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 4 of 7 Robert L. Coffman, Dynavax Technologies, USA Systems Biology Analysis of the Human Response to Hepatitis B Vaccines Using Alum or CpG Oligonucleotide Adjuvants
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 5 of 7 John D. MacMicking, Yale University, USA Discovery of IFN-Induced GBPs in Inflammasome-Mediated Host Defense
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 6 of 7 Margherita Coccia, GlaxoSmithKline Vaccines, Belgium Short Talk: Innate Immune Mechanisms and Early NK Cell Activation as a Result of MPL and QS-21 Combination Controls the Adjuvant Effect Induced by the Human Adjuvant System AS01
Thursday, April 23 \| 8:00AM - 11:15AM Intervention/Vaccines Room: Grand Sierra AB Speaker 7 of 7 Ugo D'Oro, GlaxoSmithKline Vaccines, Italy Short Talk: The Novel Adjuvant Alum-TLR7 Is Able to Potentiate the Immune Response to Glycoconjugate Vaccines
Thursday, April 23 \| 8:00AM - 11:15AM Therapeutic Interventions in Autoinflammation and Autoimmuni ty This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 6 Raphaela Theresia Goldbach-Mansky, NIAID, National Institutes of Health, USA Targeted Therapies in Autoinflammatory Diseases
Thursday, April 23 \| 8:00AM - 11:15AM Therapeutic Interventions in Autoinflammation and Autoimmuni ty This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 6 * Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA Differential Activation of Myeloid Cells by Vaccines in Humans
Thursday, April 23 \| 8:00AM - 11:15AM Therapeutic Interventions in Autoinflammation and Autoimmuni ty This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 6 Dhavalkumar D. Patel, UCB S.A., Belgium IL17 Blockade in Psoriasis and Other Autoimmune Diseases
Thursday, April 23 \| 8:00AM - 11:15AM Therapeutic Interventions in Autoinflammation and Autoimmuni ty This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 6 Christoph Klein, Ludwig-Maximilians-University, Germany Human Genetic Defects Predisposing to Hyperinflammation in the Intestinal Tract
Thursday, April 23 \| 8:00AM - 11:15AM Therapeutic Interventions in Autoinflammation and Autoimmuni ty This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 6 Donghai Wang, Duke University Medical Center, USA Short Talk: From Cholesterol Biosynthesis to Inflammation Molecular Pathogenesis of Mevalonate Kinase Deficiency
Thursday, April 23 \| 8:00AM - 11:15AM Therapeutic Interventions in Autoinflammation and Autoimmuni ty This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 6 of 6 John A. Mo, AstraZeneca, Sweden Short Talk: Radical Scavenging Nanoparticles for the Treatment of IBD
Thursday, April 23 \| 9:20AM - 9:40AM Coffee Break Room: Sierra Prefunction
Thursday, April 23 \| 11:15AM - 5:00PM On Own for Lunch
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 1 of 9 * Sarkis K. Mazmanian, California Institute of Technology, USA
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 2 of 9 Manuella Bouttier, McGill University, Canada Genomics Analysis Reveals Elevated LXRalpha Signaling Reduces M. tuberculosis Viability
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 3 of 9 Irina Tikhanovich, University of Kansas Medical Center, USA Dynamic Arginine Methylation of TRAF6 Regulates TLR Signaling
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 4 of 9 Sakthimala Jagadeesan, MGH/Harvard Medical School, USA Genome-Wide Screen Identifies Genes Involved in Gut Immunity and Homeostasis in C. elegans
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 5 of 9 Anneliese O. Speak, Wellcome Trust Sanger Institute, UK High-Throughput Mutant Mouse Characterization Is a Powerful Tool to Identify Novel Immune Phenotypes
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 6 of 9 Jacob S. Yount, Ohio State University, USA Chemoproteomics Reveals Toll-Like Receptor Fatty Acylation
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 7 of 9 Petr Broz, University of Lausanne, Switzerland GBPs Promote AIM2 Inflammasome Activation during Francisella Infection by Inducing Cytosolic Bacteriolysis and DNA Release
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 8 of 9 Claudia A. Nold-Petry, MIMR-PHI Institute of Medical Research, Australia IL-37 Requires the Receptors IL-18Ralpha and IL-1R8 (SIGIRR) to Carry out its Multi-Faceted Anti-Inflammatory Program on Innate Signal Transduction
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Systems Biology/Cytokine Pathway Room: Grand Sierra AB Speaker 9 of 9 Helene Minyi Liu, National Taiwan University, Taiwan Deacetylation-Dependent Regulation of RIG-I Activation by the HDAc6 Deacetylase Mediates Innate Anti-Viral Immunity
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 1 of 9 * Christoph Klein, Ludwig-Maximilians-University, Germany
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 2 of 9 James S. Rush, Novartis Pharma AG, Switzerland A Novel, Blocking, Fc-Silent Anti-CD40 Monoclonal Antibody Prolongs Non-Human Primate Renal Allograft Survival in the Absence of B Cell Depletion
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 3 of 9 Gerard M. McGeehan, Syndax Pharmaceuticals, USA The RORgammat Blocker, VTP-43742, Suppresses Th17 Activity Providing Greater Benefit than IL-17A Blockade in an EAE Model of Autoimmunity
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 4 of 9 Xiaoyi Yuan, Baylor College of Medicine, USA Complement C1q Regulates Inflammatory Responses in Cigarette Smoke-Induced Emphysema
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 5 of 9 Holly Legault, Biogen Idec, USA Characterization of Novel IRAK4 Small Molecule Inhibitors
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 6 of 9 Elizabeth K. Brint, University College Cork, Ireland An Anti-Tumorigenic Role for the IL-33/ST2 Axis in Colon Cancer
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 7 of 9 Sanja Arandjelovic, University of Virginia, USA Engulfment Protein ELMO1 as a Novel Regulator of Rheumatoid Arthritis
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 8 of 9 Lucile E. Wrenshall, Wright State University, USA Dimeric IL-2 Induces Necrosis of Interleukin-2 Receptor Positive Cells
Thursday, April 23 \| 2:30PM - 4:30PM Workshop 4: Novel Therapies for Inflammatory Diseases This session is from Pro-Inflammatory Diseases Room: Grand Sierra CD Speaker 9 of 9 Johanna Hol, Oslo University Hospital, Rikshospitalet, Norway Inhibition of Endothelial Notch Signaling Attenuates Inflammation
Thursday, April 23 \| 4:30PM - 5:00PM Coffee Available Room: Sierra Prefunction
Thursday, April 23 \| 5:00PM - 6:45PM Targets for Immunotherapy (Joint) Room: Grand Sierra A-D Speaker 1 of 4 * Hana Golding, US Food and Drug Administration, USA
Thursday, April 23 \| 5:00PM - 6:45PM Targets for Immunotherapy (Joint) Room: Grand Sierra A-D Speaker 2 of 4 Thomas A. Waldmann, National Institutes of Health, USA IL-15 in the Life and Death of Lymphocytes—Implications for Immunotherapy of Cancer and Autoimmune Disease
Thursday, April 23 \| 5:00PM - 6:45PM Targets for Immunotherapy (Joint) Room: Grand Sierra A-D Speaker 3 of 4 Maria Grazia Roncarolo, Stanford University School of Medicine, USA Tr1 Cells in Inflammatory Diseases
Thursday, April 23 \| 5:00PM - 6:45PM Targets for Immunotherapy (Joint) Room: Grand Sierra A-D Speaker 4 of 4 Akiko Iwasaki, HHMI/Yale University School of Medicine, USA Innate Defense Against Influenza Virus Infection
Thursday, April 23 \| 6:45PM - 7:00PM Meeting Wrap-Up: Outcomes and Future Directions (Organizers) Room: Grand Sierra A-D Speaker 1 of 1 Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA Closing Remarks
Thursday, April 23 \| 7:00PM - 8:00PM Social Hour with Lite Bites Room: Alpine Ballroom No registration fees are used to fund alcohol served at this function.
Thursday, April 23 \| 8:00PM - 11:00PM Entertainment Room: Alpine Ballroom Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.
Thursday, April 23 \| 8:00PM - 11:00PM Cash Bar Room: Alpine Ballroom
Friday, April 24 \| 10:25AM - 10:25AM Departure *Session Chair.