Web Desc
Mechanisms of Pro-Inflammatory Diseases
joint with Innate Immunity and Determinants of Microbial Pathogenesis
Organizer(s): Virginia Pascual, Mark S. Anderson and Daniel Kastner
Date: April 19 - 24, 2015
Location: Resort at Squaw Creek, Olympic Valley, CA, USA
Sponsored by AbbVie Inc., Janssen R&D: Pharmaceutical Companies of Johnson & Johnson, Journal of Molecular Cell Biology (JMCB), Merck & Co., Inc. and Theravance Biopharma. Supported by an educational grant from Celgene Corporation.
For important information on the coronavirus, please click here
Summary of Meeting:
Inflammation is a physiological process that repairs tissues in response to harmful endogenous or exogenous stimuli and involves the movement of plasma and leukocytes to the injured site. While acute inflammatory responses are generally protective, chronic states of inflammation have detrimental consequences and lead to tissue destruction and disease. Indeed, chronic inflammatory diseases, such as MS, rheumatoid arthritis, inflammatory bowel disease, systemic lupus erythematosus, and diabetes are major clinical problems today. This meeting brings together clinical and basic scientists interested in inflammation and translational research with a view to understanding basic mechanisms of inflammation and identifying novel approaches for therapeutic intervention, leveraging recent advances in basic immunology, genomics and systems biology. A particular emphasis is on human autoimmune and autoinflammatory diseases. Opportunities for interdisciplinary interactions are significantly enhanced by the concurrent meeting on 'Innate Immunity and Determinants of Microbial Pathogenesis,' which shares a keynote address and three plenary sessions with this meeting.
Scholarship Deadline: December 18 2014
Discounted Abstract Deadline: December 18 2014
Abstract Deadline: January 21 2015
Discounted Registration Deadline: February 19 2015
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
AbbVie Inc.
Educational grant from Celgene Corporation
Janssen R&D: Pharmaceutical Companies of Johnson & JohnsonJournal of Molecular Cell Biology (JMCB)Merck & Co., Inc.Theravance Biopharma
We gratefully acknowledge additional support for this conference from:
R&D Systems, a Bio-Techne brand
We gratefully acknowledge additional in-kind support for this conference from those foregoing speaker expense reimbursements:

Amgen Inc.

Novartis Institutes for BioMedical Research
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:
The Journal of Rheumatology
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI115820-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, April 19 | 4:00PM - 8:00PM
Arrival and Registration
Room: Lobby Alcove


Sunday, April 19 | 6:00PM - 8:00PM
Welcome Mixer
Room: Lobby Alcove
No registration fees are used to fund alcohol served at this function.

Monday, April 20 | 7:00AM - 8:00AM
Breakfast
Room: Alpine Ballroom


Monday, April 20 | 8:00AM - 9:30AM
Keynote Session (Joint)
Room: Grand Sierra A-D

Speaker 1 of 3
* Robert L. Modlin, University of California, Los Angeles, USA
Introduction

Monday, April 20 | 8:00AM - 9:30AM
Keynote Session (Joint)
Room: Grand Sierra A-D

Speaker 2 of 3
Richard A. Flavell, HHMI/Yale University School of Medicine, USA
Inflammasomes in Health, Dysbiosis and Disease

Monday, April 20 | 8:00AM - 9:30AM
Keynote Session (Joint)
Room: Grand Sierra A-D

Speaker 3 of 3
Zhijian 'James' Chen, University of Texas Southwestern Medical Center, USA
Innate Immune Sensing of Cytosolic Nucleic Acids

Monday, April 20 | 9:40AM - 10:00AM
Coffee Break
Room: Sierra Prefunction


Monday, April 20 | 9:50AM - 12:00PM
Innate Immunity (Joint)
Room: Grand Sierra A-D

Speaker 1 of 6
* Virginia Pascual, Cornell University, USA

Monday, April 20 | 9:50AM - 12:00PM
Innate Immunity (Joint)
Room: Grand Sierra A-D

Speaker 2 of 6
Vishva M. Dixit, Genentech, Inc., USA
New Pathways of Inflammasome Activation

Monday, April 20 | 9:50AM - 12:00PM
Innate Immunity (Joint)
Room: Grand Sierra A-D

Speaker 3 of 6
Yong-Jun Liu, Sanofi, USA
Sensing of DNA and RNA

Monday, April 20 | 9:50AM - 12:00PM
Innate Immunity (Joint)
Room: Grand Sierra A-D

Speaker 4 of 6
Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA
NLRs in Inflammasome and Non-Inflammasome Functions

Monday, April 20 | 9:50AM - 12:00PM
Innate Immunity (Joint)
Room: Grand Sierra A-D

Speaker 5 of 6
Pedro Moura-Alves, Max Planck Institute for Infection Biology, Germany
Short Talk: PAMPing AhR

Monday, April 20 | 9:50AM - 12:00PM
Innate Immunity (Joint)
Room: Grand Sierra A-D

Speaker 6 of 6
Scott W. Canna, Children's Hospital of Pittsburgh, University of Pittsburgh, USA
Short Talk: Activating Mutations in NLRC4 Cause Recurrent Macrophage Activation Syndrome: Blame it on IL-18?

Monday, April 20 | 12:00PM - 1:00PM
Poster Setup
Room: Alpine Ballroom


Monday, April 20 | 12:00PM - 2:30PM
On Own for Lunch


Monday, April 20 | 1:00PM - 10:00PM
Poster Viewing
Room: Alpine Ballroom


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 1 of 7
* Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 2 of 7
Irving C. Allen, Virginia Tech, USA
NLRX1 Attenuates Inflammation and Tumorigenesis through the Negative Regulation of AKT and NF-kappaB Signaling

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 3 of 7
Po-Lin Huang, Academia Sinica, Taiwan
Skeletal Muscle IL-15/IL-15Ralpha Promotes CD8+ T-Cell Function and Autoimmune Myositis

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 4 of 7
Sebastian Günther, University of Maryland School of Medicine, USA
Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 5 of 7
Teja Celhar, Singapore Immunology Network, Singapore
Elimination of the NLRP3 Inflammasome Prevents the Development of Lupus-Associated Traits in a Mouse Model of Autoimmunity

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 6 of 7
Rachel A. Gottschalk, NIAID, National Institutes of Health, USA
Distinct Sensitivities of NFkappaB and MAPK to TLR Ligation Support Robust Low-Noise Inflammatory Responses

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: Innate Immunity and Disease
Room: Grand Sierra CD

Speaker 7 of 7
Sebastien Tauzin, University of Wisconsin-Madison, USA
Redox and Src Family Kinase Signaling Control Macrophage-Mediated Resolution of Inflammation

Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 9
* Jae U. Jung, Keck School of Medicine of University of Southern California, USA


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 9
Emily M. Eshleman, University of Colorado School of Medicine, USA
Myeloid Cell IFNGR1 Down Regulation Exacerbates Bacterial Infections


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 9
Matteo Gentili, Institut Curie, France
Intercellular Transmission of Innate Immune Signaling by Packaging of the Second Messenger cGAMP in Viral Particles


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 9
Jarrod S. Johnson, Seattle Biomedical Research Institute, USA
HIV-1 Alters the Threshold for Type I Interferon Signaling in Dendritic Cells


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 9
Ken Chung-Ren Pang, Walter and Eliza Hall Institute of Medical Research, Australia
Sidt2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 9
Jan Rehwinkel, Weatherall Institute of Molecular Medicine, University of Oxford, UK
Lentiviruses Transfer the Antiviral Second Messenger cGAMP between Cells


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 7 of 9
Beiyun Caitlin Liu, Tufts University, USA
Type-I IFN-Independent Induction and Activation of Caspase-11 toward L. pneumophila


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 8 of 9
Clinton J. Bradfield, NIH, USA
Human GBPs Recognize a New Class of DAMPs to Mobilize Cell-Autonomous Immunity to Bacterial Pathogens


Monday, April 20 | 2:30PM - 4:30PM
Workshop 1: IFN
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 9 of 9
Jessica F. Almine, University of Dundee, UK
IFI16 and cGAS Co-Operate in DNA Sensing in Human Keratinocytes


Monday, April 20 | 4:30PM - 5:00PM
Coffee Available
Room: Sierra Prefunction


Monday, April 20 | 5:00PM - 7:00PM
Innate Triggers of Adaptive Immunity
Room: Grand Sierra CD

Speaker 1 of 5
* John J. O'Shea, NIAMS, National Institutes of Health, USA

Monday, April 20 | 5:00PM - 7:00PM
Innate Triggers of Adaptive Immunity
Room: Grand Sierra CD

Speaker 2 of 5
Mark S. Anderson, University of California, San Francisco, USA
Control of Immune Tolerance by Aire-Expressing Cells

Monday, April 20 | 5:00PM - 7:00PM
Innate Triggers of Adaptive Immunity
Room: Grand Sierra CD

Speaker 3 of 5
Hideki Ueno, Icahn School of Medicine at Mount Sinai, USA
T Follicular Helper Cells in Autoimmunity in Humans

Monday, April 20 | 5:00PM - 7:00PM
Innate Triggers of Adaptive Immunity
Room: Grand Sierra CD

Speaker 4 of 5
Averil I. Ma, University of California, San Francisco, USA
Short Talk: A20 Restricts IL1b Ubiquitination and NLRP3 Inflammasome Activity

Monday, April 20 | 5:00PM - 7:00PM
Innate Triggers of Adaptive Immunity
Room: Grand Sierra CD

Speaker 5 of 5
Simone Caielli, Baylor Institute for Immunology Research, USA
Short Talk: Oxidized Mitochondrial DNA Is a Powerful Activator of Human pDCs and Induces a Lupus-Specific CD4 T Cell Phenotype

Monday, April 20 | 5:00PM - 7:00PM
Innate Immune Sensing and Consequences in Microbial Infectio
n
This session is from Innate Immunity

Room: Grand Sierra AB

Speaker 1 of 5
* Alan Sher, NIAID, National Institutes of Health, USA


Monday, April 20 | 5:00PM - 7:00PM
Innate Immune Sensing and Consequences in Microbial Infectio
n
This session is from Innate Immunity

Room: Grand Sierra AB

Speaker 2 of 5
Jae U. Jung, Keck School of Medicine of University of Southern California, USA
Roles of Pattern Recognizing Receptors and Autophagy in Antiviral Immune Response


Monday, April 20 | 5:00PM - 7:00PM
Innate Immune Sensing and Consequences in Microbial Infectio
n
This session is from Innate Immunity

Room: Grand Sierra AB

Speaker 3 of 5
Stanley M. Lemon, University of North Carolina at Chapel Hill, USA
Type 1 Interferon Responses Determine Permissiveness and Host Species Range of Human Hepatitis A Virus


Monday, April 20 | 5:00PM - 7:00PM
Innate Immune Sensing and Consequences in Microbial Infectio
n
This session is from Innate Immunity

Room: Grand Sierra AB

Speaker 4 of 5
Genhong Cheng, University of California, Los Angeles, USA
Balancing Inflammatory Responses during Acute and Chronic Infections


Monday, April 20 | 5:00PM - 7:00PM
Innate Immune Sensing and Consequences in Microbial Infectio
n
This session is from Innate Immunity

Room: Grand Sierra AB

Speaker 5 of 5
Arun K. Mankan, University of Bonn, Institute of Molecular Medicine, Germany
Short Talk: Cytosolic RNA:DNA Hybrids Activate the cGAS-STING Axis


Monday, April 20 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Alpine Ballroom
No registration fees are used to fund alcohol served at this function.

Monday, April 20 | 7:30PM - 10:00PM
Poster Session 1
Room: Alpine Ballroom


Tuesday, April 21 | 7:00AM - 8:00AM
Breakfast
Room: Alpine Ballroom


Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 1 of 7
* Foo Y. Liew, University of Glasgow, UK

Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 2 of 7
Akira Shizuo, Osaka University, Japan
Control of the Inflammatory and Immune Responses by the Ribonuclease, Regnase-1

Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 3 of 7
Daniel Kastner, National Institutes of Health, USA
Dissecting New Inflammatory Pathways through Genetics

Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 4 of 7
Virginia Pascual, Cornell University, USA
Novel Insights into Human SLE Pathogenesis

Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 5 of 7
Robert L. Modlin, University of California, Los Angeles, USA
Innate Immunity in TB

Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 6 of 7
Hubertus Hochrein, Bavarian Nordic, Germany
Short Talk: IFN-lambda Production of CD8 cDCs in Response to DNA-Viruses, Transfected dsDNA or Cyclic-di-Nucleotides Depends on STING

Tuesday, April 21 | 8:00AM - 11:15AM
Innate Immunity in Inflammation and Disease (Joint)
Room: Grand Sierra A-D

Speaker 7 of 7
Seth L. Masters, Walter and Eliza Hall Institute, Australia
Short Talk: Aberrant Actin Depolymerization Triggers the Pyrin Inflammasome and Autoinflammatory Disease that Is Dependent on IL-18, not IL-1beta

Tuesday, April 21 | 9:20AM - 9:40AM
Coffee Break
Room: Sierra Prefunction


Tuesday, April 21 | 11:15AM - 1:00PM
Poster Setup
Room: Alpine Ballroom


Tuesday, April 21 | 11:15AM - 2:30PM
On Own for Lunch


Tuesday, April 21 | 1:00PM - 10:00PM
Poster Viewing
Room: Alpine Ballroom


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 1 of 9
* Raphaela Theresia Goldbach-Mansky, NIAID, National Institutes of Health, USA

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 2 of 9
Nagaraj Kerur, University of Kentucky, USA
Innate Immune Mechanisms of Alu RNA-Induced Age-Related Macular Degeneration

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 3 of 9
Siobhán A-L Smith, Royal College of Surgeons in Ireland, Ireland
Altered miRNA Expression in Monocytes Contributes to Dysregulated IL-16 Levels in SLE

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 4 of 9
Marcel F. Nold, Monash University, Australia
Serum Interleukin 38 Is Associated with Disease Severity and Organ Involvement in Systemic Lupus Erythematosus

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 5 of 9
Romain F. Banchereau, Baylor Institute for Immunology Research, USA
Longitudinal Immunoprofiling of SLE Patients Identifies Transcriptional Biomarkers of Disease Activity and Response to Treatment

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 6 of 9
Nelson Gekara, Umeå University, Sweden
DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 7 of 9
Nadia Jeremiah, Institute Imagine, France
An IntereSTING Germline Mutation Underlying a Familial Inflammatory Syndrome with Lupus-Like Manifestations

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 8 of 9
Dong-Ming Su, University of North Texas Health Science Center, USA
Thymic Involution Perturbs Negative Selection Leading to Increased Release of Self-Reactive T Cells that Induce Chronic Inflammation in the Elderly

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Biomarkers and Mechanisms of Disease
Room: Grand Sierra CD

Speaker 9 of 9
Hye-Lin Ha, NIAID, National Institutes of Health, USA
IL-17 Drives Psoriatic Inflammation via Distinct, Target Cell-Specific Mechanisms

Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 9
* John D. MacMicking, Yale University, USA


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 9
André Alves Dias, Oswaldo Cruz Foundation, Brazil
The Role of TLR9 Activation in the Host Immune Response during Type II Reaction in Leprosy


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 9
Robert O. Watson, Texas A&M Health Science Center, USA
cGAS Detects Mycobacterium tuberculosis DNA to Activate both Type I Interferon and Autophagy


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 9
Trude Helen Flo, Norwegian University of Science, Norway
Keap1 Regulates Inflammatory Signaling in M. avium-Infected Human Macrophages


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 9
Jennifer R. Honda, National Jewish Health, USA
Polar Lipids of Nontuberculous Mycobacteria Likely Contribute to Neutralization of Cathelicidin


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 9
Susan Realegeno, University of California, Los Angeles, USA
Identifying TLR and IFN-g Inducible Antimicrobial Responses Against Mycobacteria in Human Macrophages


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 7 of 9
Leonardo Ribeiro Batista Silva, Fundação Oswaldo Cruz, Brazil
Insulin-Like Growth Factor-I (IGF-I) Signaling Pathway Inhibits the STAT1 Activation via SOCS3 in Mycobacterium leprae-Stimulated Macrophases


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 8 of 9
Kirsten E. Wiens, New York University School of Medicine, USA
Differential Type I Interferon Induction by Distinct Mycobacterium tuberculosis Strains Despite Similar Access to the Host Cytosol


Tuesday, April 21 | 2:30PM - 4:30PM
Workshop 2: Mycobacteria
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 9 of 9
Chien-Hsiung Yu, University of Queensland Diamantina Institute, Australia
RP105 Dependent Activation of PI3Kdelta Promotes Cytokine Trafficking in Mycobacteria-Infected Macrophages


Tuesday, April 21 | 4:30PM - 5:00PM
Coffee Available
Room: Sierra Prefunction


Tuesday, April 21 | 5:00PM - 7:15PM
Sterile Nucleic Acid Sensing and Disease
Room: Grand Sierra CD

Speaker 1 of 5
* Mark S. Anderson, University of California, San Francisco, USA

Tuesday, April 21 | 5:00PM - 7:15PM
Sterile Nucleic Acid Sensing and Disease
Room: Grand Sierra CD

Speaker 2 of 5
Yanick Crow, University of Edinburgh, UK
Human Type I Interferonopathies

Tuesday, April 21 | 5:00PM - 7:15PM
Sterile Nucleic Acid Sensing and Disease
Room: Grand Sierra CD

Speaker 3 of 5
Gregory M. Barton, University of California, Berkeley, USA
Regulation of Toll-Like Receptors

Tuesday, April 21 | 5:00PM - 7:15PM
Sterile Nucleic Acid Sensing and Disease
Room: Grand Sierra CD

Speaker 4 of 5
Glen N. Barber, University of Miami, USA
STING and Sterile Inflammation

Tuesday, April 21 | 5:00PM - 7:15PM
Sterile Nucleic Acid Sensing and Disease
Room: Grand Sierra CD

Speaker 5 of 5
Matthew G. Blango, University of Utah, USA
Short Talk: Identification of Hyper-Edited, Immune-Relevant RNA in Activated Macrophages

Tuesday, April 21 | 5:00PM - 7:00PM
Innate Regulation of Adaptive Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 6
* Cathryn R. Nagler, University of Chicago, USA


Tuesday, April 21 | 5:00PM - 7:00PM
Innate Regulation of Adaptive Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 6
Foo Y. Liew, University of Glasgow, UK
The Role of Cytokines in Infection and Inflammation


Tuesday, April 21 | 5:00PM - 7:00PM
Innate Regulation of Adaptive Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 6
Alan Sher, NIAID, National Institutes of Health, USA
Cytokine and Lipid Mediator Cross-Talk in the Innate Immune Response to Mycobacterium tuberculosis


Tuesday, April 21 | 5:00PM - 7:00PM
Innate Regulation of Adaptive Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 6
Marco Colonna, Washington University School of Medicine, USA
Innate Lymphoid Cells in Immunity


Tuesday, April 21 | 5:00PM - 7:00PM
Innate Regulation of Adaptive Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 6
Jesse C. Nussbaum, University of California, San Francisco, USA
Short Talk: Group 2 Innate Lymphocytes Are Early Effectors that Cooperate with Adaptive Immunity after Helminth Infection


Tuesday, April 21 | 5:00PM - 7:00PM
Innate Regulation of Adaptive Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 6
Andrea Ablasser, Ecole Polytechnique Fédérale de Lausanne, Switzerland
Short Talk:


Tuesday, April 21 | 7:15PM - 8:00PM
Social Hour with Lite Bites
Room: Alpine Ballroom
No registration fees are used to fund alcohol served at this function.

Tuesday, April 21 | 7:30PM - 10:00PM
Poster Session 2
Room: Alpine Ballroom


Wednesday, April 22 | 7:00AM - 8:00AM
Breakfast
Room: Alpine Ballroom


Wednesday, April 22 | 8:00AM - 11:00AM
Novel Players in the Control of Inflammation
Room: Grand Sierra CD

Speaker 1 of 5
* Daniel Kastner, National Institutes of Health, USA

Wednesday, April 22 | 8:00AM - 11:00AM
Novel Players in the Control of Inflammation
Room: Grand Sierra CD

Speaker 2 of 5
Luke A. J. O'Neill, Trinity Biomedical Sciences Institute, Ireland
Metabolic Control of Inflammtion

Wednesday, April 22 | 8:00AM - 11:00AM
Novel Players in the Control of Inflammation
Room: Grand Sierra CD

Speaker 3 of 5
Michael L. Stitzel, The Jackson Laboratory for Genomic Medicine, USA
Enhancers and Type II Diabetes

Wednesday, April 22 | 8:00AM - 11:00AM
Novel Players in the Control of Inflammation
Room: Grand Sierra CD

Speaker 4 of 5
Thirumala-Devi Kanneganti, St. Jude Children's Research Hospital, USA
Regulators of Inflammatory Responses

Wednesday, April 22 | 8:00AM - 11:00AM
Novel Players in the Control of Inflammation
Room: Grand Sierra CD

Speaker 5 of 5
Benjamin Fowler, University of Kentucky, USA
Short Talk: Nucleoside Reverse Transcriptase Inhibitors Possess Intrinsic Anti-Inflammatory Activity

Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 7
* Yasmine Belkaid, NIAID, National Institutes of Health, USA


Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 7
Alan Aderem, Center for Infectious Disease Research, USA
A Systems Approach to Dissecting Immunity


Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 7
Ronald N. Germain, NIAID, National Institutes of Health, USA
Single Cell and Systems Level Analysis and Modeling of Innate Immunity


Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 7
Iain D.C. Fraser, NIAID, National Institutes of Health, USA
Interrogating Immune Signaling Systems with High-Throughput, High-Content Screening


Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 7
T. Sam Xiao, Case Western Reserve University, USA
Short Talk: Structure and Regulation of IFI16


Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 7
Roi Avraham, Broad Institute, USA
Short Talk: Single Cell Expression Analysis Reveals Co-Variation of Bacterial and Host Factors that Control Infection Outcome


Wednesday, April 22 | 8:00AM - 11:00AM
Systems Biology/Immunomics of Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 7 of 7
Johan Van Weyenbergh, KU Leuven, Belgium
Short Talk: Systemic and in situ Transcriptomics Reveal an Innate/Type I IFN Link between Oxidative Burst, Cell Death and Inflammation in Human Cutaneous Leishmaniasis


Wednesday, April 22 | 9:20AM - 9:40AM
Coffee Break
Room: Sierra Prefunction


Wednesday, April 22 | 11:00AM - 1:00PM
Poster Setup
Room: Alpine Ballroom


Wednesday, April 22 | 11:00AM - 2:30PM
On Own for Lunch


Wednesday, April 22 | 1:00PM - 10:00PM
Poster Viewing
Room: Alpine Ballroom


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 1 of 9
* Yanick Crow, University of Edinburgh, UK

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 2 of 9
Sarah L. Doyle, Trinity College Dublin, Ireland
IL-18 Immunotherapy for Neovascular AMD; Tolerability and Efficacy in Non-Human Primates

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 3 of 9
Kate Schroder, University of Queensland, Australia
Neutrophil Inflammasomes Selectively Drive IL-1beta Maturation but not Cell Death

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 4 of 9
Eric P. Hanson, National Institutes of Health, USA
Recruitment of A20 by the C-Terminal Ubiquitin-Binding Domain of NEMO Prevents Severe Inflammatory Disease in Humans

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 5 of 9
Peter R. Bunyard, Redx Pharma, UK
Genetic Deletion of GPR18 Enhances Immune Responses to Pathogenic and Antigenic Challenge

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 6 of 9
Todd Douglas, McGill University, Canada
Inflammatory Caspases in the Pathogenesis of Chronic Proliferative Dermatitis in Mice

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 7 of 9
Kiyoshi Hirahara, Graduate School of Medicine, Chiba University, Japan
Asymmetry of STAT Action in Driving IL-27 and IL-6 Transcriptional Outputs and Cytokine Specificity

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 8 of 9
Alma-Martina Cepika, Stanford School of Medicine, USA
A Blood Stimulation Assay Identifies Monocyte Hyperresponsiveness to Pro-Inflammatory Stimuli in Systemic-Onset Juvenile Idiopathic Arthritis

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3
Room: Grand Sierra CD

Speaker 9 of 9
Irina Alexandra Leaf, Biogen, USA
Pericyte MyD88 Controls Inflammatory and Fibrotic Responses to Tissue Injury

Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 9
* Laurel L. Lenz, University of Colorado, USA


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 9
Jon A. Hagar, University of North Carolina at Chapel Hill, USA
Endotoxin Signaling Potentiates Insulin-Induced Acute Hypoglycemia


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 9
Damien Arnoult, Hopital Paul Brousse, France
Endomembranes Act as Platforms for Ubiquitylated Components of NF-kappaB and IRF3 Signaling


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 9
Marina Zaitseva, Center for Biologics Evaluation and Research, USA
Critical Role of GPR14 Receptor in Prostaglandin Production by Human Monocytes in Response to MDP


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 9
Sarah E. Clark, University of Colorado, USA
Regulation of Natural Killer Cell IL-10 Production during Listeria Infection


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 9
Mathias S. Dick, University of Basel, Switzerland
Oligomerization of ASC Serves as Signal Amplification Mechanism for Inflammasomes


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 7 of 9
Naohiro Inohara, University of Michigan Medical School, USA
Interleukin-22 Bridges Local Inflammation to Systemic Protection Against Pathobionts after Pathogen-Induced Intestinal Damage


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 8 of 9
Marijke Keestra-Gounder, University of Colorado Denver, USA
The ER Stress-Induced Pro-Inflammatory Response Is Mediated by the NOD1/NOD2 Signaling Pathway


Wednesday, April 22 | 2:30PM - 4:30PM
Workshop 3: Effector Function
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 9 of 9
Shie-Liang Hsieh, Academia Sinica, Taiwan
Modulation of Influenza Virus-Induced Macrophage Activation by Decoy Receptor 3 (DcR3)


Wednesday, April 22 | 4:30PM - 5:00PM
Coffee Available
Room: Sierra Prefunction


Wednesday, April 22 | 5:00PM - 7:00PM
Epigenetic Control of Inflammation
Room: Grand Sierra CD

Speaker 1 of 4
Howard Y. Chang, Stanford University, USA
LncRNAs and Inflammation

Wednesday, April 22 | 5:00PM - 7:00PM
Epigenetic Control of Inflammation
Room: Grand Sierra CD

Speaker 2 of 4
Alexander Tarakhovsky, Rockefeller University, USA
Epigenetic Control of Inflammatory Cascades

Wednesday, April 22 | 5:00PM - 7:00PM
Epigenetic Control of Inflammation
Room: Grand Sierra CD

Speaker 3 of 4
John J. O'Shea, NIAMS, National Institutes of Health, USA
Epigenetic Control of T Cell Fate

Wednesday, April 22 | 5:00PM - 7:00PM
Epigenetic Control of Inflammation
Room: Grand Sierra CD

Speaker 4 of 4
Chrysothemis Brown, Sloan Kettering Institute, USA
Short Talk: Epigenetic Regulation of Th1 Plasticity by Retinoic Acid: A New Paradigm for the Ontogeny of Pathogenic Th17 Cells

Wednesday, April 22 | 5:00PM - 7:00PM
Microbiome and Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 5
* Alan Aderem, Center for Infectious Disease Research, USA


Wednesday, April 22 | 5:00PM - 7:00PM
Microbiome and Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 5
Cathryn R. Nagler, University of Chicago, USA
Innate Immune Regulation of Sensitization to Dietary Antigens by Commensal Bacteria


Wednesday, April 22 | 5:00PM - 7:00PM
Microbiome and Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 5
Yasmine Belkaid, NIAID, National Institutes of Health, USA
T Cell Commensals


Wednesday, April 22 | 5:00PM - 7:00PM
Microbiome and Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 5
Sarkis K. Mazmanian, California Institute of Technology, USA
The Gut Microbiome Signals through Genetic Pathways Linked to IBD


Wednesday, April 22 | 5:00PM - 7:00PM
Microbiome and Innate Immunity
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 5
Richard I. Tapping, University of Illinois, USA
Short Talk: Toll-Like Receptor 10 Is a B-Cell Intrinsic Suppressor of Adaptive Humoral Immune Responses


Wednesday, April 22 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Alpine Ballroom
No registration fees are used to fund alcohol served at this function.

Wednesday, April 22 | 7:30PM - 10:00PM
Poster Session 3
Room: Alpine Ballroom


Thursday, April 23 | 7:00AM - 8:00AM
Breakfast
Room: Alpine Ballroom


Thursday, April 23 | 8:00AM - 11:15AM
Therapeutic Interventions in Autoinflammation and Autoimmuni
ty

Room: Grand Sierra CD

Speaker 1 of 6
Raphaela Theresia Goldbach-Mansky, NIAID, National Institutes of Health, USA
Targeted Therapies in Autoinflammatory Diseases

Thursday, April 23 | 8:00AM - 11:15AM
Therapeutic Interventions in Autoinflammation and Autoimmuni
ty

Room: Grand Sierra CD

Speaker 2 of 6
* Jacques F. Banchereau, The Jackson Laboratory for Genomic Medicine, USA
Differential Activation of Myeloid Cells by Vaccines in Humans

Thursday, April 23 | 8:00AM - 11:15AM
Therapeutic Interventions in Autoinflammation and Autoimmuni
ty

Room: Grand Sierra CD

Speaker 3 of 6
Dhavalkumar D. Patel, UCB S.A., Belgium
IL17 Blockade in Psoriasis and Other Autoimmune Diseases

Thursday, April 23 | 8:00AM - 11:15AM
Therapeutic Interventions in Autoinflammation and Autoimmuni
ty

Room: Grand Sierra CD

Speaker 4 of 6
Christoph Klein, Ludwig-Maximilians-University, Germany
Human Genetic Defects Predisposing to Hyperinflammation in the Intestinal Tract

Thursday, April 23 | 8:00AM - 11:15AM
Therapeutic Interventions in Autoinflammation and Autoimmuni
ty

Room: Grand Sierra CD

Speaker 5 of 6
Donghai Wang, Duke University Medical Center, USA
Short Talk: From Cholesterol Biosynthesis to Inflammation Molecular Pathogenesis of Mevalonate Kinase Deficiency

Thursday, April 23 | 8:00AM - 11:15AM
Therapeutic Interventions in Autoinflammation and Autoimmuni
ty

Room: Grand Sierra CD

Speaker 6 of 6
John A. Mo, AstraZeneca, Sweden
Short Talk: Radical Scavenging Nanoparticles for the Treatment of IBD

Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 7
* Akiko Iwasaki, HHMI/Yale University School of Medicine, USA


Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 7
Hana Golding, US Food and Drug Administration, USA
Impact of Adjuvants on Antibody Repertoires and Affinity Maturation Against Pandemic Influenza Vaccines


Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 7
Eva Harris, University of California, Berkeley, USA
Antibodies to Dengue Virus Non-Structural Protein 1 Protect Against Endothelial Permeability and Lethal Vascular Leak


Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 7
Robert L. Coffman, Dynavax Technologies, USA
Systems Biology Analysis of the Human Response to Hepatitis B Vaccines Using Alum or CpG Oligonucleotide Adjuvants


Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 7
John D. MacMicking, Yale University, USA
Discovery of IFN-Induced GBPs in Inflammasome-Mediated Host Defense


Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 7
Margherita Coccia, GlaxoSmithKline Vaccines, Belgium
Short Talk: Innate Immune Mechanisms and Early NK Cell Activation as a Result of MPL and QS-21 Combination Controls the Adjuvant Effect Induced by the Human Adjuvant System AS01


Thursday, April 23 | 8:00AM - 11:15AM
Intervention/Vaccines
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 7 of 7
Ugo D'Oro, GlaxoSmithKline Vaccines, Italy
Short Talk: The Novel Adjuvant Alum-TLR7 Is Able to Potentiate the Immune Response to Glycoconjugate Vaccines


Thursday, April 23 | 9:20AM - 9:40AM
Coffee Break
Room: Sierra Prefunction


Thursday, April 23 | 11:15AM - 2:30PM
On Own for Lunch


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 1 of 9
* Christoph Klein, Ludwig-Maximilians-University, Germany

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 2 of 9
James S. Rush, Novartis Pharma AG, Switzerland
A Novel, Blocking, Fc-Silent Anti-CD40 Monoclonal Antibody Prolongs Non-Human Primate Renal Allograft Survival in the Absence of B Cell Depletion

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 3 of 9
Gerard M. McGeehan, Syndax Pharmaceuticals, USA
The RORgammat Blocker, VTP-43742, Suppresses Th17 Activity Providing Greater Benefit than IL-17A Blockade in an EAE Model of Autoimmunity

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 4 of 9
Xiaoyi Yuan, Baylor College of Medicine, USA
Complement C1q Regulates Inflammatory Responses in Cigarette Smoke-Induced Emphysema

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 5 of 9
Holly Legault, Biogen Idec, USA
Characterization of Novel IRAK4 Small Molecule Inhibitors

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 6 of 9
Elizabeth K. Brint, University College Cork, Ireland
An Anti-Tumorigenic Role for the IL-33/ST2 Axis in Colon Cancer

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 7 of 9
Sanja Arandjelovic, University of Virginia, USA
Engulfment Protein ELMO1 as a Novel Regulator of Rheumatoid Arthritis

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 8 of 9
Lucile E. Wrenshall, Wright State University, USA
Dimeric IL-2 Induces Necrosis of Interleukin-2 Receptor Positive Cells

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Novel Therapies for Inflammatory Diseases
Room: Grand Sierra CD

Speaker 9 of 9
Johanna Hol, Oslo University Hospital, Rikshospitalet, Norway
Inhibition of Endothelial Notch Signaling Attenuates Inflammation

Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 1 of 9
* Sarkis K. Mazmanian, California Institute of Technology, USA


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 2 of 9
Manuella Bouttier, McGill University, Canada
Genomics Analysis Reveals Elevated LXRalpha Signaling Reduces M. tuberculosis Viability


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 3 of 9
Irina Tikhanovich, University of Kansas Medical Center, USA
Dynamic Arginine Methylation of TRAF6 Regulates TLR Signaling


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 4 of 9
Sakthimala Jagadeesan, MGH/Harvard Medical School, USA
Genome-Wide Screen Identifies Genes Involved in Gut Immunity and Homeostasis in C. elegans


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 5 of 9
Anneliese O. Speak, Wellcome Trust Sanger Institute, UK
High-Throughput Mutant Mouse Characterization Is a Powerful Tool to Identify Novel Immune Phenotypes


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 6 of 9
Jacob S. Yount, Ohio State University, USA
Chemoproteomics Reveals Toll-Like Receptor Fatty Acylation


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 7 of 9
Petr Broz, University of Lausanne, Switzerland
GBPs Promote AIM2 Inflammasome Activation during Francisella Infection by Inducing Cytosolic Bacteriolysis and DNA Release


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 8 of 9
Claudia A. Nold-Petry, MIMR-PHI Institute of Medical Research, Australia
IL-37 Requires the Receptors IL-18Ralpha and IL-1R8 (SIGIRR) to Carry out its Multi-Faceted Anti-Inflammatory Program on Innate Signal Transduction


Thursday, April 23 | 2:30PM - 4:30PM
Workshop 4: Systems Biology/Cytokine Pathway
This session is from Innate Immunity
Room: Grand Sierra AB

Speaker 9 of 9
Helene Minyi Liu, National Taiwan University, Taiwan
Deacetylation-Dependent Regulation of RIG-I Activation by the HDAc6 Deacetylase Mediates Innate Anti-Viral Immunity


Thursday, April 23 | 4:30PM - 5:00PM
Coffee Available
Room: Sierra Prefunction


Thursday, April 23 | 5:00PM - 6:45PM
Targets for Immunotherapy (Joint)
Room: Grand Sierra A-D

Speaker 1 of 4
* Hana Golding, US Food and Drug Administration, USA

Thursday, April 23 | 5:00PM - 6:45PM
Targets for Immunotherapy (Joint)
Room: Grand Sierra A-D

Speaker 2 of 4
Thomas A. Waldmann, National Institutes of Health, USA
IL-15 in the Life and Death of Lymphocytes—Implications for Immunotherapy of Cancer and Autoimmune Disease

Thursday, April 23 | 5:00PM - 6:45PM
Targets for Immunotherapy (Joint)
Room: Grand Sierra A-D

Speaker 3 of 4
Maria Grazia Roncarolo, Stanford University School of Medicine, USA
Tr1 Cells in Inflammatory Diseases

Thursday, April 23 | 5:00PM - 6:45PM
Targets for Immunotherapy (Joint)
Room: Grand Sierra A-D

Speaker 4 of 4
Akiko Iwasaki, HHMI/Yale University School of Medicine, USA
Innate Defense Against Influenza Virus Infection

Thursday, April 23 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
Room: Grand Sierra A-D

Speaker 1 of 1
Jenny P.Y. Ting, University of North Carolina at Chapel Hill, USA
Closing Remarks

Thursday, April 23 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Alpine Ballroom
No registration fees are used to fund alcohol served at this function.

Thursday, April 23 | 8:00PM - 11:00PM
Entertainment
Room: Alpine Ballroom
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, April 23 | 8:00PM - 11:00PM
Cash Bar
Room: Alpine Ballroom


Friday, April 24 | 10:23AM - 10:23AM
Departure


*Session Chair
†Invited, not yet responded.