Web Desc
Cytokine JAK-STAT Signaling in Immunity and Disease
Organizer(s): Curt M. Horvath, John J. O'Shea and Stephanie S. Watowich
Date: January 10 - 14, 2016
Location: Sheraton Steamboat Resort, Steamboat Springs, CO, USA
Sponsored by Incyte Corporation, Pfizer Inc. and Theravance Biopharma
Summary of Meeting:
Cytokines are important extracellular factors that direct a variety of biological responses in normal physiology and disease. Cytokine signaling is mediated in large part through four Janus kinase (JAK) proteins and seven Signal Transducer and Activator of Transcription (STAT) proteins, and these molecules intersect with a wide array of additional intracellular signals to drive significant global alterations in gene expression. Cytokine JAK-STAT pathways are intimately associated with innate and adaptive immunity, inflammation, stem cell and developmental biology, and diverse aspects of cancer biology. As JAK-STAT pathways produce both common and unique phenotypes critical for a vast range of biological phenomena, the basic understanding of how these signal transduction cascades are regulated, function and integrate with additional cellular responses has been continuously refined by discoveries of general and pathway-specific mechanisms. Furthermore, drug discovery efforts have produced small molecules targeting JAKs and STATs that are promising agents in clinical treatment of inflammation, arthritis and a variety of cancers. This meeting, coinciding with the 25th year of the discovery of JAK-STAT signaling, will couple invited speakers who have made significant contributions to allied disciplines with cytokine JAK-STAT veterans, with ample opportunities for short talks selected from submitted abstracts.
Scholarship Deadline: September 21 2015
Discounted Abstract Deadline: September 21 2015
Abstract Deadline: October 20 2015
Discounted Registration Deadline: November 10 2015
Keystone Symposia thanks our Sponsor(s) for generously supporting this meeting:
Incyte CorporationPfizer Inc.Theravance Biopharma
We gratefully acknowledge the generous grant for this conference provided by:

National Institute of Allergy and Infectious Diseases (NIAID)
Grant No. 1R13AI120498-01
The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
We appreciate the organizations that provide Keystone Symposia with additional support, such as marketing and advertising:

Click here to view more of these organizations
Special thanks to the following for their support of Keystone Symposia initiatives to increase participation at this meeting by scientists from underrepresented backgrounds:

Click here to view more of these organizations

Program

Sunday, January 10 | 4:00PM - 8:00PM
Arrival and Registration
Room: Foyer


Sunday, January 10 | 6:00PM - 8:00PM
Welcome Mixer
Room: Foyer
No registration fees are used to fund alcohol served at this function.

Monday, January 11 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Monday, January 11 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Storm Peak/Mt. Werner

Speaker 1 of 2
* Curt M. Horvath, Northwestern University, USA

Monday, January 11 | 8:00AM - 9:00AM
Welcome and Keynote Address
Room: Storm Peak/Mt. Werner

Speaker 2 of 2
John J. O'Shea, NIAMS, National Institutes of Health, USA
Jaks and Stats in Immunity and Disease

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 1 of 7
* Stephanie S. Watowich, University of Texas MD Anderson Cancer Center, USA

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 2 of 7
* Sandra Pellegrini, Institut Pasteur, France

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 3 of 7
K. Christopher Garcia, Stanford University School of Medicine, USA
Tuning Cytokine Receptor Signaling

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 4 of 7
Andrew Brooks, University of Queensland Diamantina Institute, Australia
Mechanism of JAK2 Activation by the Growth Hormone Receptor

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 5 of 7
Jeff Babon, Walter and Eliza Hall Institute of Medical Research, Australia
Inhibition of JAK/STAT Signaling by the SOCS Family of Proteins

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 6 of 7
Ryan D. Ferrao, Genentech, USA
Short Talk: Structural and Biophysical Characterization of a JAK1 Binding Motif Shared by Class II Cytokine Receptors: Breaking the “Box1” Code

Monday, January 11 | 9:00AM - 11:30AM
Receptor Activation and STAT Signaling
Room: Storm Peak/Mt. Werner

Speaker 7 of 7
Tim R. Hercus, University of South Australia and SA Pathology, Australia
Short Talk: Function of the Beta Common Family of Cytokines

Monday, January 11 | 9:40AM - 10:00AM
Coffee Break
Room: Foyer


Monday, January 11 | 11:30AM - 1:00PM
Poster Setup
Room: Sunshine


Monday, January 11 | 11:30AM - 2:30PM
On Own for Lunch


Monday, January 11 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine


Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 1 of 10
* David E. Levy, New York University School of Medicine, USA

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 2 of 10
* Thomas A.F. Decker, Vienna Biocenter, University of Vienna, Austria

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 3 of 10
Nancy Au-Yeung, Northwestern University, USA
Chromatin Regulation of Type I Interferon-Stimulated Genes

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 4 of 10
Teresa D. Collins, University of Florida, USA
A Suppressor of Cytokine Signaling-1 Mimetic Peptide Ameliorates Lupus Pathology through Interferon-gamma Signaling Inhibition

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 5 of 10
Christine Delgado, University of Colorado Anschutz Medical Campus, USA
JAK1 and CK2 Mediate Immune Suppressive Effects of Type I Interferons and May be a Target for Host-Directed Therapy of Bacterial Infection

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 6 of 10
Nathalie M. Grandvaux, Université de Montréal, Canada
A Novel STAT2/IRF9-Dependent Pathway Mediates the Synergistic Action of IFNbeta+TNFalpha to Regulate Delayed Antiviral and Immunoregulatory Genes

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 7 of 10
Srinivasan Rengachari, EMBL-Grenoble, France
Structural Insights into ISGF3 Assembly

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 8 of 10
Kelly Shepardson, Montana State University, USA
Type I Interferons Regulate Host Susceptibility to Post-Influenza Bacterial Superinfection via STAT6

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 9 of 10
Prerak Trivedi, St. Vincent’s Institute, Australia
Preclinical Characterization of JAK1/JAK2 Inhibitors for Treatment of Type 1 Diabetes

Monday, January 11 | 2:30PM - 4:30PM
Workshop 1: All Things Interferon
Room: Storm Peak/Mt. Werner

Speaker 10 of 10
Joshua D. Milner, Columbia University, USA
Germline STAT Mutations Cause Abnormal Cross-Regulation in Disease Pathogenesis

Monday, January 11 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Monday, January 11 | 5:00PM - 7:00PM
Chromatin and Gene Regulation
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
* George R. Stark, Case Western Reserve University, USA

Monday, January 11 | 5:00PM - 7:00PM
Chromatin and Gene Regulation
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
Sandra Pellegrini, Institut Pasteur, France
Fine Tuning of Type I Interferon Response in Humans and Mice

Monday, January 11 | 5:00PM - 7:00PM
Chromatin and Gene Regulation
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
Uwe Vinkemeier, University of Nottingham Medical School, UK
STAT Protein Polymerization and its Role in Cytokine-Dependent Gene Transcription

Monday, January 11 | 5:00PM - 7:00PM
Chromatin and Gene Regulation
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
Jennifer Grandis, University of California, San Francisco, USA
Targeting STAT3 Signaling in Head and Neck Cancer

Monday, January 11 | 5:00PM - 7:00PM
Chromatin and Gene Regulation
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Yue Xiong, University of North Carolina at Chapel Hill, USA
Short Talk: The Function and Mechanism of TET DNA Dioxygenases in JAK-STAT Signaling and Antiviral Infection

Monday, January 11 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Monday, January 11 | 7:30PM - 10:00PM
Poster Session 1
Room: Sunshine


Tuesday, January 12 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 1 of 8
* John J. O'Shea, NIAMS, National Institutes of Health, USA

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 2 of 8
* Lionel B. Ivashkiv, Hospital for Special Surgery, New York, USA

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 3 of 8
Stuart G. Tangye, Garvan Institute of Medical Research, Australia
Regulation of Lymphocyte Activation and Effector Functions

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 4 of 8
Susan M. Kaech, The Salk Institute, USA
Fattening Up T Cell Memory

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 5 of 8
Mark H. Kaplan, Indiana University School of Medicine, USA
Transcriptional Regulation of T Helper Cell Development

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 6 of 8
Joseph E. Craft, Yale University, USA
STAT Regulation of Follicular T Helper Cell Development and Differentiation

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 7 of 8
Tiphanie Vogel, Washington University in St. Louis, USA
Short Talk: Altered Phosphorylation Kinetics, Cellular Location and Transcriptional Activity of a STAT3 GOF Mutation in the DNA Binding Domain

Tuesday, January 12 | 8:00AM - 11:15AM
Immune Regulation
Room: Storm Peak/Mt. Werner

Speaker 8 of 8
Massimo G. Gadina, NIAMS, National Institutes of Health, USA
Short Talk: Tofacitinib Ameliorates Murine Lupus and its Associated Vascular Damage

Tuesday, January 12 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Tuesday, January 12 | 11:15AM - 1:00PM
Poster Setup
Room: Sunshine


Tuesday, January 12 | 11:15AM - 5:00PM
On Own for Lunch


Tuesday, January 12 | 1:00PM - 10:00PM
Poster Viewing
Room: Sunshine


Tuesday, January 12 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Tuesday, January 12 | 5:00PM - 7:00PM
Inflammation
Room: Storm Peak/Mt. Werner

Speaker 1 of 6
* Mark H. Kaplan, Indiana University School of Medicine, USA

Tuesday, January 12 | 5:00PM - 7:00PM
Inflammation
Room: Storm Peak/Mt. Werner

Speaker 2 of 6
* Joseph E. Craft, Yale University, USA

Tuesday, January 12 | 5:00PM - 7:00PM
Inflammation
Room: Storm Peak/Mt. Werner

Speaker 3 of 6
Stephanie S. Watowich, University of Texas MD Anderson Cancer Center, USA
Innate Immune Regulation by STAT3

Tuesday, January 12 | 5:00PM - 7:00PM
Inflammation
Room: Storm Peak/Mt. Werner

Speaker 4 of 6
Lionel B. Ivashkiv, Hospital for Special Surgery, New York, USA
Regulation of Macrophage Activation by STAT Signaling and Epigenetic Mechanisms

Tuesday, January 12 | 5:00PM - 7:00PM
Inflammation
Room: Storm Peak/Mt. Werner

Speaker 5 of 6
Simon A. Jones, Cardiff University School of Medicine, UK
Interleukin-6 Responses in Inflammation and Immunity

Tuesday, January 12 | 5:00PM - 7:00PM
Inflammation
Room: Storm Peak/Mt. Werner

Speaker 6 of 6
Chien-Kuo Lee, National Taiwan University, Taiwan
Short Talk: STAT1 Regulates Marginal Zone B Cell Differentiation in Response to Inflammation and Infection with Blood-Borne Streptococcus Pneumoniae

Tuesday, January 12 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Tuesday, January 12 | 7:30PM - 10:00PM
Poster Session 2
Room: Sunshine


Wednesday, January 13 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 1 of 7
* Serge Y. Fuchs, University of Pennsylvania, USA

Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 2 of 7
Alessandra Sacco, Sanford-Burnham-Prebys Medical Discovery Institute, USA
STAT3 Signaling Regulates Muscle Stem Cell Function

Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 3 of 7
Christine J. Watson, University of Cambridge, UK
The Role of Stat3 in Cell Fate Switching in Mammary Gland

Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 4 of 7
Sandra E. Nicholson, Walter and Eliza Hall Institute of Medical Research, Australia
SOCS Protein Regulation of NK Cell-Mediated Tumor Immunity

Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 5 of 7
* Erika A. Bach, New York University School of Medicine, USA
JAK-STAT Signaling in Drosophila Tumor Models

Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 6 of 7
Anthony R. Green, University of Cambridge, UK
Short Talk: Cytokine-Mediated Differentiation Reflects Genome-Wide Loss of a uSTAT Transcriptional Program

Wednesday, January 13 | 8:00AM - 11:15AM
Stem Cells and Development
Room: Storm Peak/Mt. Werner

Speaker 7 of 7
Zachary C. Murphy, University of Rochester, USA
Short Talk: JAK-STAT Signaling Regulates the Survival and Terminal Maturation of Embryonic Erythroid Cells Downstream of EpoR

Wednesday, January 13 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Wednesday, January 13 | 11:15AM - 5:00PM
On Own for Lunch


Wednesday, January 13 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Wednesday, January 13 | 5:00PM - 7:00PM
Infection and Disease
Room: Storm Peak/Mt. Werner

Speaker 1 of 6
* Alessandra Sacco, Sanford-Burnham-Prebys Medical Discovery Institute, USA

Wednesday, January 13 | 5:00PM - 7:00PM
Infection and Disease
Room: Storm Peak/Mt. Werner

Speaker 2 of 6
* Christine J. Watson, University of Cambridge, UK

Wednesday, January 13 | 5:00PM - 7:00PM
Infection and Disease
Room: Storm Peak/Mt. Werner

Speaker 3 of 6
Thomas A.F. Decker, Vienna Biocenter, University of Vienna, Austria
JAK STAT Cooperation with the NFkB Pathway in the Regulation of Host Responses and Innate Immunity to Bacteria

Wednesday, January 13 | 5:00PM - 7:00PM
Infection and Disease
Room: Storm Peak/Mt. Werner

Speaker 4 of 6
Curt M. Horvath, Northwestern University, USA
Activation and Inhibition Mechanisms in IFN-JAK-STAT Signaling and Innate Antiviral Immunity

Wednesday, January 13 | 5:00PM - 7:00PM
Infection and Disease
Room: Storm Peak/Mt. Werner

Speaker 5 of 6
David E. Levy, New York University School of Medicine, USA
Mitochondrial STAT3 Supports Malignant Transformation through Metabolic Reprogramming

Wednesday, January 13 | 5:00PM - 7:00PM
Infection and Disease
Room: Storm Peak/Mt. Werner

Speaker 6 of 6
Serge Y. Fuchs, University of Pennsylvania, USA
Short Talk: Type 1 Interferons as Effectors of Genotoxic and Proteotoxic Stress: Role in Accelerated Aging and Diabetes

Wednesday, January 13 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Rainbow/Twilight
No registration fees are used to fund alcohol served at this function.

Thursday, January 14 | 7:00AM - 8:00AM
Breakfast
Room: Foyer/Rainbow/Twilight


Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 1 of 8
* Uwe Vinkemeier, University of Nottingham Medical School, UK

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 2 of 8
* Andrew Brooks, University of Queensland Diamantina Institute, Australia

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 3 of 8
Ajay Chawla, Merck Research Labs, USA
Innate Mechanisms of Thermogenesis

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 4 of 8
Ross L. Levine, Memorial Sloan Kettering Cancer Center, USA
Role of JAK-STAT Pathway Activation in MPN Pathogenesis and Therapeutic Response

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 5 of 8
Andrew Larner, Virginia Commonwealth University, USA
STAT3 Rapidly Exits and Re-Enters the Mitochondria in Cells Exposed to Oxidative Stress or Cytokines

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 6 of 8
Tony Tiganis, Monash University, Australia
PTPs and STATs in Obesity and Cancer

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 7 of 8
Jesse Balic, Hudson Institute of Medical Research, Australia
Short Talk: Requirement for STAT3 Serine 727 Phosphorylation in Gastric Tumourigenesis

Thursday, January 14 | 8:00AM - 11:15AM
Metabolic Disease and Cancer
Room: Storm Peak/Mt. Werner

Speaker 8 of 8
Marcin T. Kortylewski, Beckman Research Institute, City of Hope, USA
Short Talk: Cell-Selective Oligonucleotide STAT3 Inhibitors for Cancer Immunotherapy

Thursday, January 14 | 9:20AM - 9:40AM
Coffee Break
Room: Foyer


Thursday, January 14 | 11:15AM - 2:30PM
On Own for Lunch


Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 1 of 10
* Veronika Sexl, University of Veterinary Medicine, Austria

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 2 of 10
* Ross L. Levine, Memorial Sloan Kettering Cancer Center, USA

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 3 of 10
Etty (Tika) Benveniste, University of Alabama at Birmingham, USA
Role of the JAK/STAT Pathway in Parkinson's Disease

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 4 of 10
Dirk Fahrenkamp, RWTH Aachen University, Germany
Intramolecular Hydrophobic Interactions are Critical Mediators of STAT5 Dimerization

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 5 of 10
John S. McMurray, M.D. Anderson Cancer Center, USA
Targeting the SH2 Domain of STAT6: Potent Therapeutics for Asthma

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 6 of 10
Claudia Mertens, Rockefeller University, USA
Mutations in the Linker Domain Affect Phospho STAT3 Function and Suggest Targets for Interrupting STAT3

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 7 of 10
Jan Pencik, LBI-CR & Medical University of Vienna, Austria
Loss of IL-6/Stat3 Signaling Drives Metastatic Prostate Cancer in Mice and Men

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 8 of 10
Tiiu Saarne, AstraZeneca R&D Gothenburg, Sweden
Topical Administration of JAK1-Selective Inhibitor Reduces Airway Inflammation

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 9 of 10
Haiyan S. Li, University of Texas MD Anderson Cancer Center, USA
Dendritic Cell-Mediated Anti-Tumor Immunity is Restrained by STAT3 Suppression of Id2

Thursday, January 14 | 2:30PM - 4:30PM
Workshop 2: Therapeutic Targeting of JAK-STAT Pathways
Room: Storm Peak/Mt. Werner

Speaker 10 of 10
Rich Woessner, Blueprint Medicines, USA
Response to Checkpoint Inhibitor Antibodies is Enhanced by the Addition of STAT3 Antisense Treatment in Preclinical Tumor Models

Thursday, January 14 | 4:30PM - 5:00PM
Coffee Available
Room: Foyer


Thursday, January 14 | 5:00PM - 6:45PM
Cancer Microenvironment and Therapeutics
Room: Storm Peak/Mt. Werner

Speaker 1 of 5
* Andrew Larner, Virginia Commonwealth University, USA

Thursday, January 14 | 5:00PM - 6:45PM
Cancer Microenvironment and Therapeutics
Room: Storm Peak/Mt. Werner

Speaker 2 of 5
* Sandra E. Nicholson, Walter and Eliza Hall Institute of Medical Research, Australia

Thursday, January 14 | 5:00PM - 6:45PM
Cancer Microenvironment and Therapeutics
Room: Storm Peak/Mt. Werner

Speaker 3 of 5
Veronika Sexl, University of Veterinary Medicine, Austria
JAK-STAT in NK Cells: For the Better or Worse in Tumour Surveillance?

Thursday, January 14 | 5:00PM - 6:45PM
Cancer Microenvironment and Therapeutics
Room: Storm Peak/Mt. Werner

Speaker 4 of 5
George R. Stark, Case Western Reserve University, USA
Novel Paradigms for STAT-Mediated Gene Regulation

Thursday, January 14 | 5:00PM - 6:45PM
Cancer Microenvironment and Therapeutics
Room: Storm Peak/Mt. Werner

Speaker 5 of 5
Giorgio G. Inghirami, Weill Cornell Medical College, USA
The Pathogenetic Role of JAK/STAT Signaling Pathway in T-Cell Lymphoma

Thursday, January 14 | 6:45PM - 7:00PM
Meeting Wrap-Up: Outcomes and Future Directions
Room: Storm Peak/Mt. Werner

Speaker 1 of 1
* James E. Darnell, Rockefeller University, USA

Thursday, January 14 | 7:00PM - 8:00PM
Social Hour with Lite Bites
Room: Foyer/Sunshine
No registration fees are used to fund alcohol served at this function.

Thursday, January 14 | 8:00PM - 11:00PM
Entertainment
Room: Sunshine
Entertainment is not subsidized by conference registration fees nor any U.S. federal government grants. Funding for this expense is provided by other revenue sources.

Thursday, January 14 | 8:00PM - 11:00PM
Cash Bar
Room: Sunshine


Friday, January 15 | 10:25AM - 10:25AM
Departure


*Session Chair.